2015 March

Archive for March, 2015

Mixed pics at Making Strides Spinal Cord Injury Re – Video

March 29th, 2015

Mixed pics at Making Strides Spinal Cord Injury Re

By: Yogi Sanchez

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Mixed pics at Making Strides Spinal Cord Injury Re - Video

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G-CSF: From granulopoietic stimulant to bone marrow stem …

March 29th, 2015

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I dont have time for glamour Aminah Sagoe

March 29th, 2015

Aminah Sagoe

Aminah Sagoe recently developed a skincare range called Emmaus. She opens up on why she set up the brand

Q: How did you delve into skincare treatment?

A: The inspiration came about while I was trying to treat my skin condition called keratosis pilaris, aka chicken skin. It is a common skin condition that causes rough patches and small, acne-like bumps, usually on the arms, thighs, cheeks and buttocks. The bumps are usually white, sometimes red, and generally do not hurt or itch. The condition can be frustrating because it is difficult to treat. In my quest to find a cure, I developed a skin care range to treat the condition. I have always been a product junkie.

Q: How long did this take?

A: It took 22 months of research to come up with these products. It has been very hectic but we kept going with the flow. It can be used by both sexes and it is the first natural skincare line in this part of the world to mix plant stem cells with natural ingredients. It can be used by people with eczema, psoriasis, scaly skin and uneven skin tone but it doesnt bleach. The ingredients are extremely healthy and safe for the skin. The three step range consists of the pampering smiling beads body wash, touch of love mini towels and a soothing softness bliss body lotion that nourishes and protects the skin

Q: What does Emmaus mean?

A: It is a biblical word and signifies a rebirth or a new beginning. I am a convert; I was born a Muslim but I am now a Christian. I got converted after I got married to my husband who is a Christian. I was in my late 20s when I picked up the Bible, read it and believed. Believing in Christ has brought me so much joy, peace and clarity.

Q: What are some of the challenges you faced while developing the products?

A: The formulation took so long to be formulated because it is made up of natural products and preservatives. At some point, we had issues where one product will interact with another and that took a lot of time to fix. The products do not bleach or alter your skin colour. The process took 15 months to complete.

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I dont have time for glamour Aminah Sagoe

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Stem-cell therapy for dogs draws support, detractors

March 29th, 2015

Deltona retiree Paul Jaynes was heartbroken when his 9-year-old Labrador, Cookie, suddenly stopped walking last year. The once-athletic dog struggled to stand and, if she moved at all, collapsed after a few steps.

He carried his 90-pound companion to his truck, drove her to the vet and braced himself for the bad news. Surely she couldn't live like this.

Instead, his veterinarian told him about a newly available procedure involving stem cells. In a single day, the vet said, they could remove the cells from Cookie's fatty tissues, process them and re-inject them into her joints. She could go home immediately.

"It was very dramatic," Jaynes says. "The day after surgery, she was standing. She was hesitant, but she was standing and walking a little. I thought: 'Are you kidding me?' Within a week, she was almost back to her old self."

That was last September, and six months later Cookie is still going strong, Jaynes says. While he has no doubts about the treatment, though, some veterinarians worry that marketing of stem-cell therapy for animals has gotten ahead of the scientific research needed to validate its use.

The results, while sometimes promising, are not universal.

"Most of what you hear is anecdotal 'Oh, I tried this, and it helped my dog,'" says Dr. Jeffrey Peck, a veterinary surgeon at Affiliated Veterinary Specialists, based in Maitland. "This has grown in its marketing exponentially greater than it has grown in evidence."

Much of his practice is in orthopedics typically, dogs with hip dysplasia or arthritis. He tried using stem-cell therapy with his patients in 2008 but dropped it after a dozen cases in which he saw no improvement.

"I don't refuse to do it if a client really wants to try, but I give them my disclaimer," he says. "I tell them: 'I don't think I'm going to hurt anything. But I doubt I'm going to help anything either.'"

At $1,400 to $3,000 for the procedure, most pet owners opt out, he says.

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Stem-cell therapy for dogs draws support, detractors

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UAB Researcher Probes Role of a Master Gene in Skeletal Formation

March 29th, 2015

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Newswise BIRMINGHAM, Ala. Amjad Javed, Ph.D., of the University of Alabama at Birmingham, has taken a major step forward in understanding the bone development function of a gene called runx2, which could lead to future ways to speed bone healing, aid bone bioengineering, stem osteoporosis and reduce arthritis.

Javed, a professor in the UAB School of Dentistrys Department of Oral and Maxillofacial Surgery, says the results will contribute to future personalized medicine. This month, Javed presented this work to a standing-room-only audience at the International Association for Dental Research Annual Meeting in Boston. The work was published recently in two articles in the Journal of Bone and Mineral Research.

It was well-known that the deletion of both copies of the runx2 gene is lethal and the organism cannot form bone, teeth or cartilage.

To learn about the function of runx2 in specific cells types, Javed and his colleagues developed mice in which both copies of the runx2 gene were removed in only one of two key cells for bone tissue either chondrocytes or osteoblasts.

Our objective was to dissect and tease out which cell is really contributing what in bone development, Javed said. Runx2 is vital. But when we talk up personalized medicine, we need to identify which specialized cells to target within bone tissue.

Study of these mice (technically known as the next-generation conditional knockout runx2 model) shows that chondrocytes and osteoblasts have surprisingly different functions in bone formation during gestation or after birth:

Chondrocytes are involved in bone mineralization during embryonic development. Osteoblasts are involved in bone growth during postnatal development. This is a major step forward in understanding the biology of bones the dynamic, complex organs that are actively remodeled throughout life. Bones have cartilage-producing cells (chondrocytes), bone-creating cells (osteoblasts), bone-eating cells (osteoclasts), neuronal cells and blood-forming (hematopoietic) cells. Connective tissue and muscle surround the bones.

Chondrocytes Javeds model began with the cartilage-producing cells. We first removed the runx2 gene in chondrocytes, cells that are fundamental for every cartilage tissue in the body, Javed said. Our first surprise was lethality at birth.

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UAB Researcher Probes Role of a Master Gene in Skeletal Formation

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Human embryo modifications must be halted, scientists urge – Video

March 29th, 2015

Human embryo modifications must be halted, scientists urge
New warnings about genetic engineering are now coming from the very people trying to advance the field. Click here for the full story: http://www.cbc.ca/news/health/human-embryo-modifications-must...

By: The National

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Human embryo modifications must be halted, scientists urge - Video

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Process of Genetic Engineering – Video

March 29th, 2015

Process of Genetic Engineering

By: Almagul Tapayeva

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Process of Genetic Engineering - Video

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BABOR Launches Innovative Anti-Aging Collection ReVersive

March 28th, 2015

Delray Beach, FL (PRWEB) March 27, 2015

Inspired by the latest advances in skin aging, BABORs Research and Innovation Center has developed a groundbreaking new skincare innovation: the anti-aging collection ReVersive, with the ultra-effective RE-YOUTH COMPLEX.

ReVersive is unique, as it contains a high-performance formula with four active ingredients that interact in perfect synergy. Designed as a complete anti-aging system, ReVersive restores youthful radiance and luminosity, leaving the complexion looking firmer and smoother with a beautifully even appearance.

VISIBLE EFFECTS FOR TIMELESSLY BEAUTIFUL SKIN

In a recent study conducted by the independent research organization, Derma Consult, the ReVersive collection showed impressive results. Testing was conducted on 100 women, aged 35 to 67, and in just 4 weeks time users reported the following exciting results:

99% MORE YOUTHFUL APPEARANCE 87% ENHANCED RADIANCE 90% FIRMER SKIN

THE RE-YOUTH COMPLEX

March 28th, 2015

EVEN without surgery, one can now experience a dramatic improvement and even cure on health concerns such as diabetes, cancer, HIV, and cardiovascular diseases. This is through the stem cell technology and telomere science.

Dr. Marc Lavaro Jr., an expert on general & ocular oncology, general & ocular pharmacology, pediatric ophthalmic medicine, and Science of Epigenetics said these new technology are considered as breakthrough which repairs and rejuvenates the cells.

Lavaro, head of a molecular biology research in Gifu Prefecture, Japan and Osato Research Institute, Tokyo Japan stressed that stem cell is a kind of cell that can duplicate all kinds of cell which is why it can repair a damaged heart for instance.

In his book entitled 278+ Growth Factors which he is set to publish, he also mentioned that there are also certain organs which do not regenerate like the heart and brain but through stem cells it can revitalize.

Growth factors are stem cell stimulators that address medical conditions including diseases. Each growth factor is equivalent to 1 disease. For example, in a tumor kidney problem, stem cells produce growth factors to combat it.

Another technology is the telomere science under science of Epigenetics. Telomere is part of the chromosome and it protects it. It is responsible for the cell division and daily produces new cell to replace the dead cells.

Ang cell natin is designed to last forever but and pag-ikli ng telomere ang cause of sickness. Pero pwede na siyang marepair. Activator enzyme siya kaya reverse telomere rejuvenate cell, Lavaro explained.

The good news is the stem technology is now in the market and it comes in the form of liquid gel, capsule, and syrup. This is produced by Jeunesse , an exclusive patent pending stem cell technology advance technology, science of epigenetics, and stem cell science technology. It is also cheaper compared to the old stem technology wherein one has to pay for at least 700,000 to more than one million pesos per shot.

Jeunesse is a product of medical research conducted by Dr. Nathan Newman, the father of stem cell technology and world renowned for his cosmetic surgery and innovator of stem cell lift cutting edge cosmetic surgery, without cutting.

Dapat conscious tayo sa health natin at alamin ang tinatake natin if nagwowork talaga o hype lamang ng company, Lavaro added.

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Sungduan: Growth factors

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UCI team gets $5 million to create stem cell treatment for Huntington’s disease

March 28th, 2015

Irvine, Calif., March 26, 2015 -- Leslie Thompson of the Sue & Bill Gross Stem Cell Research Center at UC Irvine has been awarded $5 million by the California Institute for Regenerative Medicine to continue her CIRM-funded effort to develop stem cell treatments for Huntington's disease.

The grant supports her next step: identifying and testing stem cell-based treatments for HD, an inherited, incurable and fatal neurodegenerative disorder. In this project, Thompson and her colleagues will establish an HD therapy employing human embryonic stem cells that can be evaluated in clinical trials.

Over the past seven years, Thompson, a UCI professor of psychiatry & human behavior and neurobiology & behavior, and her team have used CIRM funding to produce stem cell lines "reprogrammed" from the skin cells of individuals carrying the Huntington's genetic mutation in order to study the disease. In addition, they conducted basic and early-stage transitional studies to develop a stem cell-based technique to treat areas of the brain susceptible to HD.

"These stem cells offer a possible long-term treatment approach that could relieve the tremendous suffering experienced by HD patients and their families," said Thompson, who's also affiliated with UCI's Institute for Memory Impairments and Neurological Disorders (UCI MIND). "We appreciate CIRM and the millions of people in the state of California for generously supporting breakthrough stem cell research."

With this award, CIRM has granted Thompson $10.3 million for her HD work. Overall, UCI has received $105 million from the state-funded agency.

Thompson said that her group has identified a highly promising neural stem cell line that shows disease-modifying activity in HD mice. These neural stem cells were grown from human embryonic stem cells at UC Davis. The researchers also will conduct essential preclinical efficacy and safety studies in HD mice with these cells.

Over the span of the 2-year grant, Thompson said, the goal is to finalize work that will lead to a pre-investigational-new-drug meeting with the Food & Drug Administration and a path forward for clinical trials with the neural stem cells.

"This investment will let us further test the early promise shown by these projects," said Jonathan Thomas, chair of the CIRM governing board. "Preclinical work is vital in examining the feasibility, potential effectiveness and safety of a therapy before we try it on people. These projects all showed compelling evidence that they could be tremendously beneficial to patients. We want to help them build on that earlier research and move the projects to the next level."

HD is a devastating degenerative brain disorder with no disease-modifying treatment or cure. Current approaches only address certain symptoms of HD and do not change its course.

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UCI team gets $5 million to create stem cell treatment for Huntington's disease

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My message in a bottle, writes Lisa Ray

March 27th, 2015

My bone marrow began sending me messages long before I Learned to listen..I was exhausted, pale, drained, and tired all of the time. I eventually landed myself in the emergency room, and was handed a full membership to the cancer club. I was diagnosed with multiple myeloma, an incurable blood cancer.

That was June 23, 2009.

As it turned out I was very fortunate. I beat the statistical odds and circumstances were in my favour. After four months of chemo and steroids, I was able to use my own stem cells in what is called an autologous stell cell transplant.

My stem cell transplant was a journey to my very core. It's like witnessing a rebirth. It's awe-inspiring and essential. Visualizing those 'yellow' cells stream their way back into my bone marrow opened my eyes to the singular power stem cells bring into our world.

But I was also reminded of Michael Pinto the undertaker in Bombay.

'Grave Problems Resurrected here'

That's so not gonna happen. Not on my resurrection.

My passage through illness taught me that the knowledge of the curative properties of stem cells needs to be shared to offer hope of renewed life. If you knew what medical science can do with stem cells, and if you saw what I did in the labs, through microscropes, you too would feel like using both hands to scoop those secrets out into the world.

Occasionally I gloss over my past cancer club membership--my treatment, my illnessbut then I am remember what a profound reboot my body has gone through, and I remember why. It's true that the deepest crises are moments of great opportunity; an event that shocks you into seeing with your heart. It is a place that combines survival with celebration.

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My message in a bottle, writes Lisa Ray

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Pause Hydra Creme -Menopause Skin care – Video

March 27th, 2015

Pause Hydra Creme -Menopause Skin care
Menopause Skin Care By http://www.phytomone.com/menopause-skin-care/ Benefits of Pause Hydra Crme *Specifically designed for menopausal skin *Uses rich source of plant hormones to correct...

By: Phytomone Ltd

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Pause Hydra Creme -Menopause Skin care - Video

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The Florida Center for Brain Tumor Research and Accelerate Brain Cancer Cure Award $350,000 to Florida-Based Researchers

March 27th, 2015

Washington, DC (PRWEB) March 27, 2015

The Florida Center for Brain Tumor Research (FCBTR), in partnership with Accelerate Brain Cancer Cure (ABC2), awarded $350,000 to support brain cancer research at three leading Florida institutions: University of Florida, The Scripps Research Institute and H. Lee Moffitt Cancer Center and Research Institute. The awards support studies with a clear development path and potential to provide meaningful improvements in treatment outcomes for patients in the near future.

The awards fund research in areas on the cutting edge of scientific inquiry, including development of innovative gene, virus, nanoparticle, and immunity-based therapies. The 4 award recipients, in alphabetical order, are

This year, the FCBTR/ABC2 Grants Program received a record number of applications. Twenty-three applications were received from researchers at six centers, including Mayo Clinic, Moffitt, Scripps, University of Florida, University of Miami, and University of West Florida.

The Florida legislature is to be congratulated, again, on establishing a program, the Florida Center for Brain Tumor Research, which continues to bring the worlds best brain tumor scientists to our state, said Dr. William Friedman, Chairman of Neurosurgery at the University of Florida. It has been an honor to collaborate with ABC2 on this important scientific endeavor for Florida.

"Were honored to partner with FCBTR to build a world-class brain cancer research network in Florida," said Max Wallace, CEO of Accelerate Brain Cancer Cure. "Thanks to the fundraising support from patients, families and loved ones participating in ABC2s Florida Brain Cancer 5k, were able to commit significant funding directly into research that holds the potential to hasten the discovery of a cure."

Since 2006, the FCBTR at the Evelyn F. and William L. McKnight Brain Institute of the University of Florida has worked with hospitals statewide to collect tissue and disseminate data on brain tumors, creating a powerful tool to facilitate clinical trials, funding opportunities and research collaborations. In addition to providing brain tumor tissue for research to Floridas scientists, FCBTR participated in The Cancer Genome Atlas, the research program that has helped set the standards for characterizing the genomic underpinnings of dozens of cancers on a large scale. Since its founding in 2001, ABC2 has fueled advancement in the field by funding outstanding and novel translational research to world-renowned researchers and creating novel collaborations with the medical community and academia, industry and government. Together, since 2010, FCBTR and ABC2 have together funded more than $925,000 in Florida-based brain tumor research.

About The Florida Center for Brain Tumor Research The Florida Center for Brain Tumor Research is a collaborative effort and its Scientific Advisory Council includes top researchers from H. Lee Moffitt Cancer Center and Research Institute, Mayo Clinic, University of Florida, Cleveland Clinic Florida, Scripps Research Institute, UFHealth Cancer Center Orlando Health, University of Miami and a representative of neurosurgeons in private practice. FCBTR has sponsored statewide Brain Tumor Biomedical Technology Summits to encourage collaboration. To learn more, please visit http://fcbtr.ufl.edu/

About Accelerate Brain Cancer Cure Accelerate Brain Cancer Cure is a venture philanthropy 501(c) (3) nonprofit organization that drives cutting-edge research and treatments for brain tumors. Through strategic partnerships with medical research centers, early-stage biotechnology companies and large multi-national pharmaceutical companies ABC2 has awarded more than $20 million in brain tumor research funding to highly qualified investigators and physician-scientists from 42 institutions and companies. The organization works to raise awareness about brain cancer and promotes advancements in critical scientific research through research grants and partnerships. To learn more, please visit http://www.abc2.org.

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The Florida Center for Brain Tumor Research and Accelerate Brain Cancer Cure Award $350,000 to Florida-Based Researchers

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Scientists Spot Gene Tied to Severe Autism in Girls

March 27th, 2015

By Dennis Thompson HealthDay Reporter

WEDNESDAY, March 25, 2015 (HealthDay News) -- Researchers say they've discovered a new genetic cause of autism, singling out a rare gene mutation that appears to hamper normal brain development early on in powerful ways.

The gene, CTNND2, provides instructions for making a protein called delta-catenin, which plays crucial roles in the nervous system, said senior author Aravinda Chakravarti, a professor in the Johns Hopkins University School of Medicine's Institute of Genetic Medicine.

His research team found that a group of girls with severe autism carried CTNND2 mutations that appeared to reduce the effectiveness of delta-catenin, potentially affecting their neurological development.

"There are many, many proteins that in fact 'moonlight,' doing many, many different things," Chakravarti said. "Maybe the severity of the effect of delta-catenin comes from the fact that when you lose function of this protein, you lose not just one function but many functions. Although that remains to be shown, it is strongly implicated by our study."

Autism spectrum disorder is a neurological and developmental disorder that begins early in life. The cause is not known, although scientists suspect genes play a role.

The researchers discovered the CTNND2 gene's link to autism using an approach that focuses on rare and extreme cases of autism, according to the study released online March 25 in the journal Nature.

By focusing on extreme cases, they believe they will discover genes that have a more powerful effect on brain development and help explain the root causes of autism.

"If we study rare and extreme forms, they are both genetic and they represent very early neurodevelopmental events," Chakravarti said.

The researchers chose to study girls with autism because they are far less likely to have autism than boys. When girls do develop the disorder, their symptoms tend to be severe.

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Scientists Spot Gene Tied to Severe Autism in Girls

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