Mayo researcher Abba Zubair is sending stem cells for study on the International Space Station – Florida Times-Union
Posted: February 17, 2017 at 12:41 pm
As a boy growing up in Nigeria, Abba Zubair dreamed of becoming an astronaut.
But as he prepared to apply to college, an adviser told him to find a different path.
He said it may be a long time before Nigeria sends rockets and astronauts into space, so I should consider something more practical, Zubair saud.
He decided to become a physician, and is currently the medical and scientific director of the Cell Therapy Laboratory at the Mayo Clinic in Jacksonville. And while hell almost certainly never get to make a journey outside the Earths atmosphere himself, if the weather stays good Saturday hell be sending a payload into space.
A SpaceX Falcon 9 rocket is scheduled to launch at 10:01 a.m. Saturday from the Kennedy Space Center on a cargo delivery mission to the International Space Station. Among the cargo it will be carrying are several samples of donated adult stem cells from Zubairs research lab.
Zubair believes adult stem cells, extracted from bone marrow, are the future of regenerative medicine. Currently at the Mayo Clinic in Jacksonville they are being used in clinical trials to treat knee injuries and transplanted lungs.
But a big problem with using stem cells to treat illnesses is that it may require up to 200 million cells to treat a human being and the cells take a long time to reproduce. Based on studies using simulators on Earth, Zubair believes that the stem cells will more quickly mass produce in microgravity.
Thats the hypothesis hell be testing as the stem cells from his lab spend a month aboard the space station. Astronauts will conduct experiments measuring changes in the cells. They will then be returned on an unmanned rocket and Zubair will continue to study them in his lab.
We want to understand the process by which stem cells divide so we can grow them at a faster rate and also so we can suppress them when treating cancer, he said.
Zubair became interested in the idea of sending stem cells into space four years ago, when he learned of a request for proposals that involved medicine and outer space. Hes been trying to arrange to send stem cells into space for three years.
In May 2015, he sent stem cells to the edge of space as a hot-air balloon carried a capsule filled with cells from his lab to about 100,000 feet then dropped the capsule. The idea was to test how the cells handled re-entry into the Earths atmosphere.
It turned out well, he said. The cells were alive and functioning.
Zubair was supported in that effort as he is being supported in sending cells to the space station by the Center for Applied Spacee Technology. Its chief executive is Larry Harvey, a retired Navy pilot and former astronaut candidate who lives in Orange Park.
While stem cells have myriad potential medical applications, one that particularly interests Zubair is the use of them in treating stroke patients. Its a personal cause to Zubair, whose mother died of a stroke in 1997.
Weve shown that an infusion of stem cells at the site of stroke improves the inflammation and also secretes factors for the regeneration of neurons and blood vessels, he said.
Zubair hasnt entirely given up on his old dream of being an astronaut. Hes applied for the civilian astronaut program. But he doesnt expect that to happen.
Im not sure I made the cut, he said. I just wanted to apply.
And he realizes what a long, strange trip hes made.
I have come so far from Africa to here, he said, and now Im sending stem cells into space.
Charlie Patton: (904) 359-4413
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