Archive for the ‘Crispr’ Category

Here's a helpful hint for you: Ignore the market volatility. If you watch your stocks continually, the up-and-down swings could make you a nervous wreck. Invest with a long-term perspective, and the temporary market gyrations will be much less bothersome.

The good news is that there are plenty of stocks that provide opportunities to deliver excellent long-term returns. Here are three stocks that could even double your money within the next few years.

Image source: Getty Images.

CRISPR Therapeutics (NASDAQ:CRSP) isn't too far away from doubling this year, with its shares up close to 80%. But the biotech stock should still have plenty of room to run.

You'll want to especially watch CRISPR Therapeutics' lead pipeline candidate, CTX001. CRISPR and its big partner Vertex Pharmaceuticalsare currently evaluating the gene-editing therapy in early stage clinical studies targeting rare blood diseases beta-thalassemia and sickle cell disease. The companies have already reported encouraging preliminary results from these studies and expect to announce additional data in the next few months. CTX001 holds the potential to essentially cure these diseases.

CRISPR Therapeutics also has a big opportunity with its three allogeneic chimeric antigen receptor T-cell (CAR-T) therapies in early stage clinical testing. Allogeneic CAR-T therapies use immune cells called T-cells from healthy individuals that are genetically engineered to target specific types of cancer then infused into sick patients. Current CAR-T therapies on the market use the sick patients' own T-cells -- an approach that's a lot slower and costlier than allogeneic therapies should be. CRISPR expects to report results from its early stage trial of one its CAR-T therapies, CTX110, by the end of this year.

Sure, there's a real risk that CRISPR Therapeutics' gene-editing programs will flop. But so far, investors have plenty of reasons to be cautiously optimistic. If CTX001 or any of the company's allogeneic CAR-T therapies succeed in clinical testing, CRISPR Therapeutics should easily double in the not-too-distant future.

Fastly (NYSE:FSLY) has taken investors on a really wild ride so far in 2020. The tech stock has had seven swings of at least 20% in just the last three months. But even with the turbulence, Fastly is still up more than 350% year to date.

The company's name hints at its underlying business. Fastly focuses on speeding up the delivery of apps and data over the internet through content delivery networks (CDNs) and edge computing. CDNs reduce the physical distance between servers and end users with a widespread distributed platform of servers. Edge computing takes a somewhat similar approach by moving app and data processing close to the cloud's edge -- the point where corporate networks connect with the cloud.

Fastly's addressable market currently totals more than $35 billion. It could grow much bigger than that with the unstoppable migration of apps to the cloud. Fastly has less than 1% of this market right now, giving the company a massive growth opportunity.

The company's biggest customer is TikTok, the video-sharing social network that has been at the center of a political firestorm recently. Until a deal is completely finalized to separate TikTok from its China-based owner ByteDance, Fastly's shares could remain highly volatile. However, Fastly's long-term prospects look great.

If you have any doubts about how hot the U.S. cannabis market is, just look atInnovative Industrial Properties (NYSE:IIPR). IIP's shares have soared more than 60% so far this year and have skyrocketed close to 600% over the last three years.

IIP ranks as the leading real estate investment trust (REIT) focused on the medical cannabis industry. It buys properties from medical cannabis operators, then turns around and leases the properties back to the operators. This helps tenants raise cash while giving IIP a steady revenue stream.

The way for IIP to double is pretty simple: Keep doing what it has been doing. IIP currently owns 63 medical cannabis properties in 16 states, up from 46 properties in 14 states at the end of 2019. The company's attractive dividend, which currently yields nearly 3.8%, makes it even easier for IIP to deliver tremendous returns for investors.

It's possible that the legalization of marijuana at the federal level in the U.S. could pave the way for more rivals to enter IIP's market. However, marijuana legalization isn't a slam dunk by any means. And even if IIP faces increased competition in the future, the growth in the overall U.S. cannabis market should enable this stock to continue its winning ways.

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3 Stocks That Could Double Your Money - The Motley Fool

Dublin, Sept. 30, 2020 (GLOBE NEWSWIRE) -- The "Global Precision Medicine Market: Focus on Ecosystem, Technology, Application, Country Data (21 Countries), and Competitive Landscape - Analysis and Forecast, 2020-2030" report has been added to ResearchAndMarkets.com's offering.

Global Precision Medicine Market to Reach $278.61 Billion by 2030

Precision medicine refers to the medicine developed as per an individual's genetic profile. It provides guidance regarding the prevention, diagnosis, and treatment of diseases. The segmentation of the population is done depending on the genome structure of the individuals and their compatibility with a specific drug molecule.

In the precision medicine market, the application of molecular biology is to study the cause of a patient's disease at the molecular level, so that target-based therapies or individualized therapies can be applied to cure the patient's health-related problems.

This industry is gaining traction due to the increasing awareness about healthcare among individuals, integration of smart devices such as smartphones and tablets into healthcare, and increasing collaborations and agreements of IT firms with the diagnostics and biopharmaceutical companies for the development of precision diagnostic tools.

Within the research report, the market is segmented on the basis of product type, ecosystem application, and region, which highlight value propositions and business models useful for industry leaders and stakeholders. The research also comprises country-level analysis, go-to-market strategies of leading players, future opportunities, among others, to detail the scope and provide 360-degree coverage of the domain.

Key Topics Covered:

1 Product Definition

2 Research Scope

3 Research Methodology

4 Global Precision Medicine Market Overview4.1 Market Definition4.2 Precision Medicine: A Frontier in the Genesis of Patient-centric Medicine4.3 Precision Medicine: Remodeling the One-Size-Fits-All Theory to Individually Tailored Therapy4.4 Initiatives and Programs4.5 Precision Medicine: Enabling Technologies and Applications4.5.1 Innovators4.5.1.1 3D DNA Printing4.5.1.1.1 Introduction4.5.1.1.2 Role of 3D DNA Printing4.5.1.2 RNA-Seq4.5.1.2.1 Introduction4.5.1.2.2 Role of RNA-Seq in Precision Medicine4.5.1.2.3 Key Players4.5.1.3 4D Molecular Imaging4.5.1.3.1 Introduction4.5.1.3.2 Role of 4D Molecular Imaging in Precision Medicine4.5.1.3.3 Key Players4.5.2 Early Adopters4.5.2.1 CRISPR4.5.2.1.1 Introduction4.5.2.1.2 Role of CRISPR in Precision Medicine4.5.2.1.3 Key Players4.5.2.2 Blockchain4.5.2.3 Imaging Informatics4.5.3 Early Majority4.5.3.1 Artificial Intelligence (AI)4.5.3.2 Circulating Free DNA (cfDNA)4.5.3.3 Big Data4.5.3.4 Next-Generation Sequencing (NGS)4.5.3.5 Health Informatics4.5.3.6 Bioinformatics4.5.4 Late Majority4.5.4.1 Polymerase Chain Reactions (PCR)4.5.4.2 Microarray4.6 COVID-19 Impact on the Global Precision Medicine Market

5 Market Dynamics5.1 Overview5.2 Market Drivers5.2.1 Advancement of Sequencing Technologies5.2.2 Rising Prevalence of Chronic Diseases5.2.3 Growing Demand for Preventive Care5.2.4 Shifting the Significance in Medicine, from Reaction to Prevention5.2.5 Reducing Adverse Drug Reactions Through Pharmacogenomics Test5.2.6 Potential to Reduce the Overall Healthcare Cost Across the Globe5.3 Market Restraints5.3.1 Unified Framework for Data Integration5.3.2 Limited Knowledge about Molecular Mechanism/ Interaction5.3.3 Lack of Robust Reimbursement Landscape5.3.4 Regulatory Hurdles5.4 Market Opportunities5.4.1 Targeted Gene Therapy5.4.2 Expansion into the Emerging Markets5.4.3 Collaboration and Partnerships Across Value Chain to Accelerate the Market Entry

6 Industry Insights6.1 Patent Analysis6.2 Legal Requirements and Regulations6.3 Pipeline Analysis6.4 Legal Requirements and Framework by the FDA6.5 Legal Requirements and Framework by the EMA6.6 Legal Requirements and Framework by the MHLW

7 Competitive Landscape7.1 Synergistic Activities7.1.1 Product launches, Enhancements, and Upgradation7.1.2 Product Approvals7.1.3 Mergers and Acquisitions7.1.4 Business Expansion7.2 Market Share Analysis7.2.1 Market Share Analysis by Applied Sciences, 20197.2.2 Market Share Analysis by Precision Diagnostics, 20197.2.3 Market Share Analysis by Precision Therapeutics, 20197.2.4 Market Share Analysis by Digital Health and IT, 2019

8 Global Precision Medicine Market (by Ecosystem)8.1 Overview8.2 Applied Sciences8.2.1 Genomics8.2.2 Global Precision Medicine Genomics Market (by Technology)8.2.2.1 Polymerase Chain Reaction (PCR)8.2.2.2 Next-Generation Sequencing (NGS)8.2.2.3 Genome Editing8.2.2.4 Other Technologies8.2.3 Pharmacogenomics8.2.4 Other Applied Sciences8.3 Precision Diagnostics8.3.1 Molecular Diagnostics (MDx)8.3.2 Global Precision Medicine Molecular Diagnostics Market (by Type)8.3.2.1 Non-Invasive Prenatal Testing (NIPT)8.3.2.2 Companion Diagnostics8.3.2.3 Liquid Biopsy8.3.2.4 Other Molecular Diagnostics8.3.3 Medical Imaging8.3.3.1 Global Precision Medicine Medical Imaging Market (by Type)8.3.3.1.1 Imaging Analytics8.3.3.1.2 Imaging Computer-Aided Detection (CADx)8.3.3.2 Global Precision Medicine Medical Imaging Market (by Region)8.4 Digital Health and Information Technology8.4.1 Global Precision Medicine Digital Health and Information Technology Market (by Type)8.4.1.1 Clinical Decision Support Systems (CDSS)8.4.1.2 Big Data Analytics8.4.1.3 IT Infrastructure8.4.1.4 Genomics Informatics8.4.1.5 In-Silico Informatics8.4.1.6 Mobile Health8.5 Precision Therapeutics8.5.1 Global Precision Medicine Therapeutics Market (by Type)8.5.1.1 Clinical Trials8.5.1.2 Cell Therapy8.5.1.3 Drug Discovery and Research8.5.1.4 Gene Therapy

9 Global Precision Medicine Market (by Application)9.1 Overview9.2 Oncology9.2.1 Cancer Precision Medicine Drugs and Indications9.3 Infectious Diseases9.3.1 Infectious Diseases Precision Medicine Drugs and Indications9.4 Neurology9.4.1 Neurology Precision Medicine Drugs and Indications9.5 Cardiovascular9.5.1 Cardiovascular Precision Medicine Drugs/Tests/ and Indications9.6 Lifestyle and Endocrinology9.6.1 Endocrinology Precision Medicine Drugs and Indications9.7 Gastroenterology9.7.1 Gastroenterology Precision Medicine Drugs and Indications9.8 Other Applications9.8.1 Precision Drugs for Other Applications

10 Global Precision Medicine Market, (by Region)

11 Company Profiles11.1 Company Overview11.2 Role of Abbott Laboratories in Global Precision Medicine Market11.3 Financials11.4 Key Insights About Financial Health of the Company

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Global Precision Medicine Market 2020-2030: Remodeling the One-Size-Fits-All Theory to Individually Tailored Therapy - GlobeNewswire

The report is an all-inclusive research study of the global CRISPR And CRISPR-Associated (Cas) Genes Market taking into accounts the growth factors, recent trends, developments, opportunities, and competitive landscape. The CRISPR And CRISPR-Associated (Cas) Genes Market analyst and researchers have done a wide analysis of the global CRISPR And CRISPR-Associated (Cas) Genes Market with the help of research methodologies such as PESTLE and Porters Five Forces breakdown. They have provided exact and consistent market data and useful recommendations with an aim to help the players gain an insight into the overall current and upcoming market scenario.

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Leading manufacturers of CRISPR And CRISPR-Associated (Cas) Genes Market:

Caribou BiosciencesAddgeneCRISPR THERAPEUTICSMerck KGaAMirus Bio LLCEditas MedicineTakara Bio USAThermo Fisher ScientificHorizon Discovery GroupIntellia TherapeuticsGE Healthcare Dharmacon

The report presents a detailed competitive landscape along with a comprehensive analysis of the market share and size, product range, product innovation, technological advancements, and market patterns. The CRISPR And CRISPR-Associated (Cas) Genes Market report incorporates the study of recent developments in the market, such as product launches, mergers, acquisitions, collaborations, joint ventures, and partnerships, among others. The report offers a futuristic outlook of the market scenario for the forecast period of 2020-2026. The CRISPR And CRISPR-Associated (Cas) Genes Market regional analysis covers North America, Europe, Latin America, Asia-Pacific, and Middle East & Africa.

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CRISPR And CRISPR-Associated (Cas) Genes Market can be segmented into Product Types as

Genome EditingGenetic engineeringgRNA Database/Gene LibrarCRISPR PlasmidHuman Stem CellsGenetically Modified Organisms/CropsCell Line Engineering

CRISPR And CRISPR-Associated (Cas) Genes Market can be segmented into Applications as

Biotechnology CompaniesPharmaceutical CompaniesAcademic InstitutesResearch and Development Institutes

To breakdown the huge study that spreads through geographies, products, and end-use segments, among other market-specific segments, the authors present the CAGR of each segment during the years of anticipate. CAGR is a simplistic illustration of enlargement that visibly projects which segment register the highest/least growth through the forecast period 2020-2026.

The newest report about the CRISPR And CRISPR-Associated (Cas) Genes market provides a thorough estimate of the business vertical in question, alongside a brief overview of the industry segments. An extremely workable estimation of the present industry scenario has been delivering in the study, and the CRISPR And CRISPR-Associated (Cas) Genes market size with regards to the revenue and volume have also been mention.

Do You Have Any Query Or Specific Requirement? Ask to Our Industry[emailprotected]:

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Highlights of the Report

Table of Contents:

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CRISPR And CRISPR-Associated (Cas) Genes Market Comprehensive Study Explores Huge Growth with Demand by Forecast 2024 - The Market Records

Global Genome Editing Market: Overview

Also known as genome editing with engineered nucleases (GEEN), genome editing is a method of altering DNA within a cell in a safe manner. The technique is also used for removing, adding, or modifying DNA in the genome. By thus editing the genome, it is possible to change the primary characteristic features of an organism or a cell.

The global genome editing market can be segmented on the basis of delivery method, technology, application, and geography. By technology, the global genome editing market can be segmented into Flp-In, CRISPR, PiggyBac, and ZFN. Based on delivery method, in vivo and ex vivo can be the two broad segments of the global genome editing market. By application, the global genome editing market can be categorized into medicine, academic research, and biotechnology.

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Global Genome Editing Market: Key Trends

Since genome editing is gaining rising adoption in the domain of scientific research for attaining a better understanding of biological aspects of organisms and how they work, the global genome editing market is likely to promise considerable growth over the forthcoming years. More importantly, genome editing is being used by medical technologies, where it can be used for modifying human blood cells which can then be placed back in the body for treating conditions such as AIDS and leukemia. The technology can also be potentially utilized to combat infections such as MRSA as well as simple genetic disorders including hemophilia and muscular dystrophy.

Global Genome Editing Market: Market Potential

As more easy-to-use and flexible genome technologies are being developed, greater potential of genome editing is being recognized across bioprocessing and treatment modalities. For instance, in May 2017, MilliporeSigma announced that it successfully developed a novel genome editing tool which can make the CRISPR system more productive, specific, and flexible. The researchers thus have a more number of experimental options along with faster results.

All this can lead to a growing rate of drug development, enabling access to more advanced therapies. Proxy-CRISPR, the new technique, makes access to earlier inaccessible aspects of the genome possible. As most of the existing CRISPR systems cannot manage without re-engineering of human cells, the new method is expected to gain more popularity by virtue of the elimination of the need for re-engineering, simplifying the procedures.

Several other market players are focusing on clinical studies with a view to produce effective treatments for different health conditions. For example, another major genome editing firm, Editas Medicine, Inc. announced the results of its pre-clinical study displaying the success of the CEP290 gene present in the retina of primates in the same month. With the positive results of the study, the companys belief in the vast potential of its candidate in the treatment of a genetically inherited retinal degenerative disease, Leber congenital amaurosis type 10, affecting childrens eyesight has been reinforced.

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Global Genome Editing Market: Regional Outlook

By geography, the global genome editing market can be segmented into Latin America, Europe, Asia Pacific, the Middle East and Africa, and North America. North America registered the highest growth in the past, and has been claiming the largest portion of the global genome editing market presently. The extraordinary growth of this region can be attributed to greater adoption of cutting edge technologies across several research organizations. The U.S., being the hub of research activities, is expected to emerge as the leading contributor. Asia Pacific is also likely to witness tremendous demand for genome editing over the forthcoming period, assisting the expansion of the global genome editing market.

Global Genome Editing Market: Competitive Analysis

CRISPR THERAPEUTICS, Caribou Biosciences, Inc., Sigma Aldrich Corporation, Sangamo, Intellia Therapeutics, Inc., Editas Medicine, Thermo Fisher Scientific, Inc., and Recombinetics, Inc are some of the key firms operating in the global genome editing market.

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Genome Editing Market Poised to Expand at a Robust Pace Over 2025 - The Daily Chronicle

On September 10, 2020, the Patent Trial and Appeal Board (PTAB) decided key motions in Interference No. 106,115,University of California v. Broad Institute. The interference involves 10 patent applications of the University of California (The Regents of the University of California, University of Vienna, and Emmanuelle Charpentier, collectively referred to as "UC") and 13 patents and one patent application of Broad Institute (The Broad Institute, Massachusetts Institute of Technology, and Presidents and Fellows of Harvard College, collectively referred to as "Broad"), all directed to the use of CRISPR-Cas9 to edit eukaryotic genomes. Broad and UC had argued these motions before the PTAB in May 2020.1

This decision is the latest turn in a long battle between Broad and UC. In a previous round of interference, Broad was able to secure its U.S. patents covering CRISPR-Cas9 in eukaryotes. The current interference puts these patents in question again. If UC prevails, Broad would lose its CRISPR-Cas9 eukaryote patents. Notably, UC also owns patents generally directed to CRISPR-Cas9 and not particularly to eukaryotes, which are not involved in this interference. Even if UC loses this interference, its general CRISPR-Cas9 patent claims would remain unaffected.

The PTAB decision recognized Broad as having the earliest effective filing date, but turned down its request to call off the current interference altogether. While the former gives Broad an advantage in proving it invented first, the latter appears to be a significant setback. The decision thus does not settle the dispute, but rather moves it to the next stage, where each party may submit actual evidence, such as lab notebooks, to prove they invented the disputed CRISPR-eukaryote system first. This stage may be rather long and complicated, and the parties may face increased pressure to settle.

A patent interference is a proceeding formerly used to determine who first invented a claimed invention. Interferences were phased out in a 2012 legislation, but patents or applications with effective filing dates before March 2013 still can be subject to an interference. To simplify the proofs of first invention, the disputed invention is defined in a "count" based on the parties' claims.

Details

Interference No. 106,115 is the second interference between Broad and UC over the CRISPR-Cas9 technology. The first interference between the parties ended in 2018 after an appeal, with the conclusion that the parties' claims did not in fact interfere because Broad's invention, directed to CRISPR-Cas9 in eukaryotic cells, would not have been obvious in light of UC's invention, which claims the CRISPR-Cas9 system generically. The current interference was triggered by new claims UC filed shortly after conclusion of the first interference, which have essentially the same scope as Broad's claims that survived the first interference. The patent examiner decided the new UC claims were allowable except for a potential interference with Broad's claims, and the PTAB subsequently declared the second interference on June 24, 2019.

The PTAB's decision on September 10 mainly addressed three issues: 1) whether the PTAB should recognize either party's first provisional application as its earliest effective filing date; 2) whether the first interference as affirmed by the Federal Circuit should bar or "estop" the current interference; and 3) whether Broad's request for a broader "count" should be granted.

Regarding the earliest effective filing date, each party requested the benefit of its first provisional application. Having the earliest recognized filing date makes one party the "senior party," which means the party is presumed to be the first inventora big advantage in a priority contest. Any other party would be a "junior party." In the current decision, the PTAB found that Broad's first provisional application, filed December 12, 2012, provided a constructive reduction to practice of an embodiment within the count, and UC's request for benefit to its first priority date was denied. The PTAB held that UC's earlier applications lacked discussion of PAM sequences, sample target DNA sequences, and special instructions or conditions necessary to accommodate the eukaryotic cellular environment. The PTAB found that these failings were not overcome until UC's third provisional application, which was filed on January 28, 2013. Accordingly, the PTAB redeclared the interference with Broad as the senior party and UC as the junior party.

On the estoppel issue, Broad requested judgment against UC because the earlier interference should have decided all issues between the parties. Broad argued that UC should be barred from pursuing its new claims, because Broad's claims involved in the two proceedings are the same, and the same issues based on the same facts were already litigated in the first interference. The PTAB denied Broad's request, explaining that the first interference did not involve priority or patentability of either party, and did not decide those issues, much less all issues that may be argued before the Board. The PTAB was also not persuaded that the counts in the two interferences were directed to the same subject matter. In reaching its decision, the PTAB had to distinguish several USPTO authorities, which might provide Broad with procedural arguments on appeal if it loses priority.

On the third issue, Broad moved for the PTAB to interpret its claims broadly and to broaden the current count defining the scope of disputed subject matter and the proofs for priority. Any claim involved in the interference that is not patentably distinct from the count is grouped with the count. As a result, the losing party would lose any claims patentably indistinct from the count. In the current interference, the original count was directed to a eukaryotic cell comprising CRISPR-Cas9 system with a single guide RNA. Broad requested PTAB to construe its claims reciting "guide RNA" as encompassing both single guide RNA and dual guide RNA, and to substitute the original count with one that covers both single and dual guide RNAs. Broad presumably requested this change because its earliest proofs of invention involved the use of dual guide RNA. The PTAB considered the parties' arguments and declarations and denied these motions, mainly based on Broad's own applications, which stated that "chimeric RNA," "chimeric guide RNA," "single guide RNA,"all of which mean a single guideand the term "guide RNA" are used interchangeably.

Broad moved alternatively for numerous claimsclaims that do not recite a single guide, claims that recite a Cas9 derived from a different species than that was in the provisional applications, and claims that recite two nuclear localization sequencesto be deemed outside of the scope of the original count. The PTAB held that Broad's arguments that these claims were patentably distinct from the count were not supported.

Both UC and Broad have remarked on the PTAB's decision. A UC spokesperson noted that the university, while disagreeing with the accordance of benefits, is pleased that the PTAB has ruled in its favor in most instances, and "remains confident that the PTAB will ultimately recognize that [UC and its affiliated research team] was first to invent the CRISPR-Cas9 technology in eukaryotic cells."2Broad, on the other hand, largely called for a settlement for the parties to move beyond the disputes and "focus on using CRISPR technology to solve today's real-world problems."3

While the PTAB decision declared Broad as the senior party, Broad's priority date is only 47 days before UC's. The interference will now move to the priority phase, where each party may present evidencefor example, actual lab recordsto establish its actual date of the invention. The PTAB has provided time periods for submission of priority motions and oppositions to the motions. These time periods go until May 7, 2021, after which an oral hearing may be ordered. Although Broad won the status of senior party, the retention of the (narrower) original count might impair Broad's ability to contest priority, and certainly its inability to convince the PTAB to end the interference without a priority contest appears to be a significant setback for Broad. This mix of outcomeswith Broad receiving an advantage on priority but with UC prevailing on the terms of the priority contestleaves both parties with considerable uncertainty, possibly increasing pressure to settle.

[1] Patent Trial and Appeal Board Hears Argument in CRISPR Patent Priority Dispute, Wilson Sonsini Alert, https://www.wsgr.com/en/insights/patent-trial-and-appeal-board-hears-argument-in-crispr-patent-priority-dispute.html.

[2] See Jon Cohen, The Latest Round In The CRISPR Patent Battle Has an Apparent Victor, but The Fight Continues, Science (September 11, 2020), https://www.sciencemag.org/news/2020/09/latest-round-crispr-patent-battle-has-apparent-victor-fight-continues.

[3] For Journalists: Statements and Background on the Crispr Patent Process, Broad Communications, https://www.broadinstitute.org/crispr/journalists-statement-and-background-crispr-patent-process (last updated September 10, 2020).

See the article here:
Patent Trial and Appeal Board Issues Decision on CRISPR Patent Priority Dispute - JD Supra

The research study presented in this report offers complete and intelligent analysis of the competition, segmentation, dynamics, and geographical advancement of the Global Japan CRISPR/Cas9 Market. The research study has been prepared with the use of in-depth qualitative and quantitative analyses of the global Japan CRISPR/Cas9 market. We have also provided absolute dollar opportunity and other types of market analysis on the global Japan CRISPR/Cas9 market.

It takes into account the CAGR, value, volume, revenue, production, consumption, sales, manufacturing cost, prices, and other key factors related to the global Japan CRISPR/Cas9 market. All findings and data on the global Japan CRISPR/Cas9 market provided in the report are calculated, gathered, and verified using advanced and reliable primary and secondary research sources. The regional analysis offered in the report will help you to identify key opportunities of the global Japan CRISPR/Cas9 market available in different regions and countries.

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The authors of the report have segmented the global Japan CRISPR/Cas9 market as per product, application, and region. Segments of the global Japan CRISPR/Cas9 market are analyzed on the basis of market share, production, consumption, revenue, CAGR, market size, and more factors. The analysts have profiled leading players of the global Japan CRISPR/Cas9 market, keeping in view their recent developments, market share, sales, revenue, areas covered, product portfolios, and other aspects.

segment by Type, the product can be split intoGenome EditingGenetic engineeringgRNA Database/Gene LibrarCRISPR PlasmidHuman Stem CellsGenetically Modified Organisms/CropsCell Line Engineering

Market segment by Application, split intoBiotechnology CompaniesPharmaceutical CompaniesAcademic InstitutesResearch and Development Institutes

Based on regional and country-level analysis, the CRISPR/Cas9 market has been segmented as follows:North AmericaUnited StatesCanadaEuropeGermanyFranceU.K.ItalyRussiaNordicRest of EuropeAsia-PacificChinaJapanSouth KoreaSoutheast AsiaIndiaAustraliaRest of Asia-PacificLatin AmericaMexicoBrazilMiddle East & AfricaTurkeySaudi ArabiaUAERest of Middle East & Africa

In the competitive analysis section of the report, leading as well as prominent players of the global CRISPR/Cas9 market are broadly studied on the basis of key factors. The report offers comprehensive analysis and accurate statistics on revenue by the player for the period 2015-2020. It also offers detailed analysis supported by reliable statistics on price and revenue (global level) by player for the period 2015-2020.The key players covered in this studyCaribou BiosciencesIntegrated DNA Technologies (IDT)CRISPR TherapeuticsMerckMirus BioEditas MedicineTakara BioThermo Fisher ScientificHorizon Discovery GroupIntellia TherapeuticsAgilent TechnologiesCellectaGenScriptGeneCopoeiaSynthego

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Japan CRISPR/Cas9 Market Size and Forecast

In terms of region, this research report covers almost all the major regions across the globe such as North America, Europe, South America, the Middle East, and Africa and the Asia Pacific. Europe and North America regions are anticipated to show an upward growth in the years to come. While Japan CRISPR/Cas9 Market in Asia Pacific regions is likely to show remarkable growth during the forecasted period. Cutting edge technology and innovations are the most important traits of the North America region and thats the reason most of the time the US dominates the global markets. Japan CRISPR/Cas9 Market in South, America region is also expected to grow in near future.

The Japan CRISPR/Cas9 Market report highlights is as follows:

This Japan CRISPR/Cas9 market report provides complete market overview which offers the competitive market scenario among major players of the industry, proper understanding of the growth opportunities, and advanced business strategies used by the market in the current and forecast period.

This Japan CRISPR/Cas9 Market report will help a business or an individual to take appropriate business decision and sound actions to be taken after understanding the growth restraining factors, market risks, market situation, market estimation of the competitors.

The expected Japan CRISPR/Cas9 Market growth and development status can be understood in a better way through this five-year forecast information presented in this report

This Japan CRISPR/Cas9 Market research report aids as a broad guideline which provides in-depth insights and detailed analysis of several trade verticals.

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Japan CRISPR/Cas9 Market size and Key Trends in terms of volume and value 2019-2026 - The Daily Chronicle

ZUG, Switzerland and CAMBRIDGE, Mass. and BOSTON, Sept. 22, 2020 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (Nasdaq: CRSP) and Vertex Pharmaceuticals Incorporated(Nasdaq: VRTX) today announced the European Medicines Agency (EMA) has granted Priority Medicines (PRIME) designation to CTX001, an investigational, autologous, ex vivo CRISPR/Cas9 gene-edited therapy for the treatment of severe sickle cell disease (SCD).

PRIME is a regulatory mechanism that provides early and proactive support to developers of promising medicines, to optimize development plans and speed up evaluations so these medicines can reach patients faster. The goal of PRIME is to help patients benefit as early as possible from innovative new therapies that have demonstrated the potential to significantly address an unmet medical need. PRIME designation was granted based on clinical data from CRISPR and Vertexs ongoing Phase 1/2 trial of CTX001 in patients with severe SCD.

About CTX001CTX001 is an investigational, autologous, ex vivo CRISPR/Cas9 gene-edited therapy that is being evaluated for patients suffering from transfusion-dependent beta thalassemia (TDT) or severe SCD, in which a patients hematopoietic stem cells are engineered to produce high levels of fetal hemoglobin (HbF; hemoglobin F) in red blood cells. HbF is a form of the oxygen-carrying hemoglobin that is naturally present at birth, which then switches to the adult form of hemoglobin. The elevation of HbF by CTX001 has the potential to alleviate transfusion requirements for TDT patients and reduce painful and debilitating sickle crises for SCD patients.

Based on progress in this program to date, CTX001 has been granted Regenerative Medicine Advanced Therapy (RMAT), Fast Track, and Orphan Drug designations from the U.S. Food and Drug Administration (FDA), and Orphan Drug Designation from the European Commission, for both TDT and SCD.

CTX001 is being developed under a co-development and co-commercialization agreement between CRISPR Therapeutics and Vertex. CTX001 is the most advanced gene-editing approach in development for TDT and SCD.

About CLIMB-111The ongoing Phase 1/2 open-label trial, CLIMB-Thal-111, is designed to assess the safety and efficacy of a single dose of CTX001 in patients ages 12 to 35 with TDT. The trial will enroll up to 45 patients and follow patients for approximately two years after infusion. Each patient will be asked to participate in a long-term follow-up trial.

About CLIMB-121The ongoing Phase 1/2 open-label trial, CLIMB-SCD-121, is designed to assess the safety and efficacy of a single dose of CTX001 in patients ages 12 to 35 with severe SCD. The trial will enroll up to 45 patients and follow patients for approximately two years after infusion. Each patient will be asked to participate in a long-term follow-up trial.

About the Gene-Editing Process in These TrialsPatients who enroll in these trials will have their own hematopoietic stem and progenitor cells collected from peripheral blood. The patients cells will be edited using the CRISPR/Cas9 technology. The edited cells, CTX001, will then be infused back into the patient as part of a stem cell transplant, a process which involves, among other things, a patient being treated with myeloablative busulfan conditioning. Patients undergoing stem cell transplants may also encounter side effects (ranging from mild to severe) that are unrelated to the administration of CTX001. Patients will initially be monitored to determine when the edited cells begin to produce mature blood cells, a process known as engraftment. After engraftment, patients will continue to be monitored to track the impact of CTX001 on multiple measures of disease and for safety.

About the CRISPR-Vertex CollaborationCRISPR Therapeutics and Vertex entered into a strategic research collaboration in 2015 focused on the use of CRISPR/Cas9 to discover and develop potential new treatments aimed at the underlying genetic causes of human disease. CTX001 represents the first treatment to emerge from the joint research program. CRISPR Therapeutics and Vertex will jointly develop and commercialize CTX001 and equally share all research and development costs and profits worldwide.

About CRISPR TherapeuticsCRISPR Therapeutics is a leading gene editing company focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. CRISPR/Cas9 is a revolutionary gene editing technology that allows for precise, directed changes to genomic DNA. CRISPR Therapeutics has established a portfolio of therapeutic programs across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine and rare diseases. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic collaborations with leading companies including Bayer, Vertex Pharmaceuticals and ViaCyte, Inc. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Cambridge, Massachusetts, and business offices in San Francisco, California and London, United Kingdom. For more information, please visit http://www.crisprtx.com.

CRISPR Therapeutics Forward-Looking Statement This press release may contain a number of forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, as well as statements regarding CRISPR Therapeutics expectations about any or all of the following: (i) the status of clinical trials (including, without limitation, the expected timing of data releases) and discussions with regulatory authorities related to product candidates under development by CRISPR Therapeutics and its collaborators, including expectations regarding the benefits of PRIME designation; (ii) the expected benefits of CRISPR Therapeutics collaborations; and (iii) the therapeutic value, development, and commercial potential of CRISPR/Cas9 gene editing technologies and therapies. Without limiting the foregoing, the words believes, anticipates, plans, expects and similar expressions are intended to identify forward-looking statements. You are cautioned that forward-looking statements are inherently uncertain. Although CRISPR Therapeutics believes that such statements are based on reasonable assumptions within the bounds of its knowledge of its business and operations, forward-looking statements are neither promises nor guarantees and they are necessarily subject to a high degree of uncertainty and risk. Actual performance and results may differ materially from those projected or suggested in the forward-looking statements due to various risks and uncertainties. These risks and uncertainties include, among others: potential impacts due to the coronavirus pandemic, such as the timing and progress of clinical trials; the potential for initial and preliminary data from any clinical trial and initial data from a limited number of patients (as is the case with CTX001 at this time) not to be indicative of final trial results; the potential that CTX001 clinical trial results may not be favorable; that future competitive or other market factors may adversely affect the commercial potential for CTX001; uncertainties regarding the intellectual property protection for CRISPR Therapeutics technology and intellectual property belonging to third parties, and the outcome of proceedings (such as an interference, an opposition or a similar proceeding) involving all or any portion of such intellectual property; and those risks and uncertainties described under the heading Risk Factors in CRISPR Therapeutics most recent annual report on Form 10-K, quarterly report on Form 10-Q and in any other subsequent filings made by CRISPR Therapeutics with the U.S. Securities and Exchange Commission, which are available on the SEC's website at http://www.sec.gov. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date they are made. CRISPR Therapeutics disclaims any obligation or undertaking to update or revise any forward-looking statements contained in this press release, other than to the extent required by law.

About VertexVertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has multiple approved medicines that treat the underlying cause of cystic fibrosis (CF) a rare, life-threatening genetic disease and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational small molecule medicines in other serious diseases where it has deep insight into causal human biology, including pain, alpha-1 antitrypsin deficiency and APOL1-mediated kidney diseases. In addition, Vertex has a rapidly expanding pipeline of genetic and cell therapies for diseases such as sickle cell disease, beta thalassemia, Duchenne muscular dystrophy and type 1 diabetes mellitus.

Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London, UK. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia and Latin America. Vertex is consistently recognized as one of the industry's top places to work, including 10 consecutive years on Science magazine's Top Employers list and top five on the 2019 Best Employers for Diversity list by Forbes. For company updates and to learn more about Vertex's history of innovation, visit http://www.vrtx.com or follow us on Facebook, Twitter, LinkedIn, YouTube and Instagram.

Vertex Special Note Regarding Forward-Looking StatementsThis press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, including, without limitation, statements regarding CTX001s PRIME designation or its development, the potential benefits of CTX001, our plans and expectations for our clinical trials and clinical trial sites, and the status of our clinical trials of our product candidates under development by us and our collaborators, including activities at the clinical trial sites and potential outcomes. While Vertex believes the forward-looking statements contained in this press release are accurate, these forward-looking statements represent the company's beliefs only as of the date of this press release and there are a number of risks and uncertainties that could cause actual events or results to differ materially from those expressed or implied by such forward-looking statements. Those risks and uncertainties include, among other things, that data from the company's development programs, including its programs with its collaborators, may not support registration or further development of its compounds due to safety, efficacy or other reasons, and other risks listed under Risk Factors in Vertex's annual report and subsequent quarterly reports filed with the Securities and Exchange Commission and available through the company's website at http://www.vrtx.com. Vertex disclaims any obligation to update the information contained in this press release as new information becomes available.(VRTX-GEN)

CRISPR Therapeutics Investor Contact:Susan Kim, +1 617-307-7503susan.kim@crisprtx.com

CRISPR Therapeutics Media Contact:Rachel EidesWCG on behalf of CRISPR+1 617-337-4167reides@wcgworld.com

Vertex Pharmaceuticals IncorporatedInvestors:Michael Partridge, +1 617-341-6108orZach Barber, +1 617-341-6470orBrenda Eustace, +1 617-341-6187

Media:mediainfo@vrtx.comorU.S.: +1 617-341-6992orHeather Nichols: +1 617-839-3607orInternational: +44 20 3204 5275

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CRISPR Therapeutics and Vertex Pharmaceuticals Announce Priority Medicines (PRIME) Designation Granted by the European Medicines Agency (EMA) to...

"The CRISPR QC applications clearly demonstrate that our differentiated, high value, Cardean Transistor technology can be manufactured at scale and adopted to pressing market applications with major unmet needs." - Rob Lozuk, CBO of Cardea

SAN DIEGO (PRWEB) September 22, 2020

CRISPR QC, a pioneer in streamlining CRISPR quality control testing, announced today the launch of CRISPR-BIND, a rapid and highly sensitive tool to characterize gRNA and CRISPR-Cas interactions. CRISPR-BIND is the first in a suite of Quality Control capabilities. Built upon Cardeas Biology-gated Transistors (Cardean Transistors) and an automated, high throughput liquid handler, CRISPR-BIND generates highly sensitive electronic signals rather than optics or labels to enhance CRISPR researchers ability to perform rapid assessments of gRNA Cas interactions directly at the lab bench. This includes, but is not limited to, monitoring the interactions and stability of a variety of modified gRNAs with engineered Cas enzymes. CRISPR QC will commercialize CRISPR-BIND in the United States along with the world leading CRISPR experts at COBO Technologies who will offer the product across Europe.

There is a high demand in the European market to rapidly characterize gRNAs and Cas variants for CRISPR-based applications, says Jens-Ole Bock, CEO and Founder of COBO Technologies. This powerful and innovative CRISPR QC platform will support the growing need for new sensitive QC solutions in the pharma and biotech segments and add an important new tool to the CRISPR research community.

CRISPR QC is Cardeas first commercial partner and CRISPR-BIND is the first of a series of CRISPR QC applications that will come out of the partnership.

"Upcoming product generations will offer alternate ways and perspectives on what the optimal guide RNA and Cas combination will be in varying environmental conditions and provide the user with insight to the ideal solutions for different CRISPR applications. Users will be able to both work in amplicons of rare samples, as well as in whole genomic unamplified DNA, says Rob Lozuk, CBO of Cardea. The CRISPR QC applications clearly demonstrate that our differentiated, high value, Cardean Transistor technology can be manufactured at scale and adopted to pressing market applications with major unmet needs. In addition, were thrilled to be working with CRISPR QC to develop this breakthrough technology and partner with COBO Technologies as their European distributor to ensure global access to these innovative technologies.

This is the first of many commercial partnerships coming out of the Cardea Innovation Partnership Program, says Michael Heltzen, CEO and Co-founder of Cardea. Im pleased with the markets response and we will continue to partner with world leading companies to deliver breakthrough applications to disrupt markets.

CRISPR-BIND will initially be available to a select number of industry leaders and CRISPR-focused academic research groups. For more information about CRISPR-BIND, visit CRISPR QCs website.

About Cardea BioCardea is linking biology directly up to computers for the very first time by building a Tech+Bio Infrastructure and offering chipsets based on proprietary Biology-gated Transistors, or Cardean Transistors. These transistors leverage graphene, a nanomaterial that in contrast to the common semiconductor material silicon, is biocompatible and a near perfect conductor due to only being one atom thick. It that way replaces optical static observations with interactive live-streams of multi-omics signal analysis, representing a new life science observation paradigm where multi-omics data-streams will be the new norm instead of most of the current standard technologies that are single-omics frozen-in-time datasets. Together with their Innovation Partners, Cardea can link biology directly to compute power and convert real-time biological signals to digital information, allowing for immediate biological insight and a new generation of applications Linking up to Life.

About CRISPR QCCRISPR QC is pioneering streamlined CRISPR quality control tools to accelerate research while improving accuracy and performance. With capabilities stretching from optimizing CRISPR designs and identifying the most optimal conditions to determining binding interactions and running quantitative analysis of amplicons and whole genomic DNA, their services save researchers both time and resources. Powered by Cardea and built upon automated high throughput liquid handling systems, their platform is optics-free and entirely electronic to eliminate risk of human errors and biology-distorting sample preparation.

Partnership inquiries Rob LozukChief Business Officerpublicrelations@cardeabio.com

Media inquiriesAmanda ZimmerMarketing Managermarketing@cardeabio.com

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Cardea Bio Announces Global Launch of First Proprietary Powered by Cardea Product in Partnership with CRISPR QC - PR Web

Dublin, Sept. 21, 2020 (GLOBE NEWSWIRE) -- The "Global CRISPR & Cas Genes Market Size, Share & Trends Analysis by Product & Service (Vector-based Cas, DNA-free Cas, Cell Line Engineering), Application, End Use, and Segment Forecasts 2020-2027" report has been added to ResearchAndMarkets.com's offering.

The global clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) genes market size is expected to reach USD 4.88 billion by 2027, expanding at a CAGR of 16.6% from 2020 to 2027.

CRISPR & Cas Genes Market Report Highlights

The product segment is anticipated to dominate the market throughout the forecast period. This is attributed to the presence of enhanced individual products that can serve multiple purposes including genome engineering, specific genome cleavage using gRNAs, easy gene knockouts, along with reduced off-target cutting, and increased specificity

Cell line engineering services accounted for the largest market share in 2019. The development of this technology has simplified the genome engineering process to a large extent

In biomedical applications, genome engineering held the largest revenue share in 2019 as a result of an increase in the adoption of genome editing techniques for modifications in germline and therapeutics development

Recent advancements in CRISPR/Cas genome editing allow targeted modification in crops, thereby promising crop improvement and revenue generation in the market

A significant number of research studies carried out to develop disease-specific novel therapies and the presence of a huge clinical pipeline that integrates the application of this gene-editing technology are expected to boost revenue generation for the biotechnology and pharmaceutical companies segment

Asia Pacific is anticipated to witness the fastest growth over the forecast period. China holds a significant position in the CRISPR market and is increasingly exploring genome-editing for the development of medicines. The country has launched several CRISPER-based clinical trials, especially for cancer treatment.

Rise in the adoption of CRISPR technology in epigenetics, therapeutics, human germline editing, plant genome editing, and other fields of biotechnology is expected to drive the market.

Presence of a large number of service providers that provide knockout, knock-in, gene repression, gene activation, and other cell line engineering services propel the growth of cell line engineering services. In biomedical applications, genome engineering held the largest revenue share in 2019. Adoption of gene editing techniques for human- and non-human-based genomic engineering is one of the key factors that drive the segment.

The molecular scissor can facilitate the detection of viruses, allowing the development of cost-effective, robust, and rapid point-of-care diagnostics. It allows the detection of viruses at a level of molecular concentration that researchers rarely assess. Sherlock Bioscience estimated that a CRISPR-powered diagnostic test would be available in the future at a reasonable price. In recent times, the most important innovation has been the development of a test for COVID-19.

In March 2020, Mesa Biotech announced FDA authorization for its Accula device, a hand-held COVID-19 diagnostic test. Similarly, in April 2020, CSIR lab announced the development of a paper-strip test for Covid-19 that uses CRISPR-Cas9 to target and identifies the genomic sequences of the virus. Unlike the PCR tests, this test is available at a very low price, USD 6.59 (INR 1 = USD 0.013). Therefore, such initiatives are expected to encourage other players to leverage this crisis and launch novel products.

Key Topics Covered:

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Chapter 1 Research Methodology

Chapter 2 Executive Summary2.1 Market Snapshot, 2019 (USD Million)

Chapter 3 Crispr And Cas Genes Market Variables, Trends & Scope3.1 Market Trends & Outlook3.2 Market Segmentation & Scope3.3 Market Lineage Outlook3.3.1 Parent Market Outlook3.3.2 Related/Ancillary Market Outlook3.4 Crispr And Cas Genes: Patent Landscape3.4.1 By End - Use Settings3.4.2 By Variants Of Crispr Enzymes3.5 Penetration And Growth Prospect Mapping, By Biomedical Applications, 20193.6 Potential Threat Analysis To Crispr Technology3.6.1 Variations In The Crispr System3.7 Investors Perspective Analysis3.8 User Perspective Analysis3.9 Technology Mapping In Crispr Genome Editing Workflow3.10 Developments And Innovations For Analysis Of Off - Target Effects3.11 Crispr Technologies: Clinical Penetration3.11.1 Human Therapeutics3.11.2 Diagnostics3.11.3 Microbiome Research And Drug Resistance3.11.4 Animal Disease Models

Chapter 4 Industry Outlook4.1 Market Dynamics4.1.1 Market Driver Analysis4.1.1.1 Rising Adoption In Diverse Fields Of Biotechnology4.1.1.1.1 Epigenetics4.1.1.1.2 Medicine4.1.1.1.3 Human Germline Editing4.1.1.1.4 Tool For Qualitative And Quantitative Plant Genome Editing4.1.1.2 Technological Advancements In Crispr4.1.1.3 Introduction Of Anti - Crispr Protein4.1.1.4 Ongoing Competition For Crispr Commercialization4.1.2 Market Restraint Analysis4.1.2.1 Off - Target Effects Of Crispr Technology4.1.2.2 Intellectual Property Disputes Pertaining To Cas4.1.2.3 Ethical Concerns And Implications With Respect To Human Genome Editing4.1.3 Market Opportunity Analysis4.1.3.1 Expanding Gene & Cell Therapy Area4.1.3.2 Government Fund In Genomic R&D4.1.4 Market Challenge Analysis4.1.4.1 Risks Pertaining To The Usage Of Genetically Modified Food4.2 Policy Making & Regulation For Genetic Modification Using Crispr4.3 Porter's Five Forces Analysis4.4 SWOT Analysis, By Factor (Political & Legal, Economic, And Technological)

Chapter 5 Competitive Landscape5.1 Companies (Diagnostic & Drug Developers) Leveraging Gene Editing Technologies5.2 Major Deals & Strategic Alliances Analysis5.3 Market Entry Strategies5.3.1 Crispr Therapeutics: Business Translation5.3.2 Crispr Gene Editing Companies' Toolboxes5.4 Crispr And Cas Genes Market: Pipeline Analysis5.4.1 Editas Medicine5.4.2 Intellia Therapeutics, Inc.5.4.3 Crispr Therapeutics5.4.4 Caribou Biosciences, Inc.5.4.5 Egenesis5.4.6 Beam Therapeutics5.4.7 Ksq Therapeutics5.4.8 Cibus

Chapter 6 Product & Service Business Analysis6.1 Crispr And Cas Genes Market: Product & Service Movement Analysis6.2 By Product6.2.1 Global Crispr And Cas Genes Products Market, 2016 - 2027 (USD Million)6.2.2 Kits & Enzymes6.2.3 Global Crispr And Cas Genes Kits And Enzymes Market, 2016 - 2027 (USD Million)6.2.3.1 Vector - Based Cas96.2.3.2 Dna - Free Cas96.2.4 Libraries6.2.5 Design Tools6.2.6 Antibodies6.2.7 Others6.3 By Service6.3.1 Global Crispr And Cas Genes Service Market, 2016 - 2027 (USD Million)6.3.2 Cell Line Engineering6.3.3 Grna Design6.3.4 Microbial Gene Editing6.3.5 Dna Synthesis

Chapter 7 Application Business Analysis7.1 Crispr And Cas Genes Market: Application Movement Analysis7.2 Biomedical7.2.1 Global Crispr And Cas Genes Market For Biomedical, 2016 - 2027 (USD Million)7.2.2 Genome Engineering7.2.3 Disease Model Studies7.2.4 Functional Genomics7.2.5 Epigenetics7.2.6 Others7.3 Agriculture

Chapter 8 End - Use Business Analysis8.1 Crispr And Cas Genes Market: End - Use Movement Analysis8.1.1 Biotechnology & Pharmaceutical Companies8.1.2 Academics & Government Research Institutes8.1.3 Contract Research Organizations (Cros)

Chapter 9 Regional Business Analysis

Chapter 10 Company Profiles

Astrazeneca

Addgene

Caribou Biosciences, Inc.

Cellectis

Crispr Therapeutics

Editas Medicine, Inc.

Egenesis

F. Hoffmann - La Roche Ltd.

Horizon Discovery Group Plc

Genscript

Danaher Corporation

Intellia Therapeutics, Inc.

Lonza

Merck Kgaa

New England Biolabs

Takara Bio, Inc.

Thermo Fisher Scientific, Inc.

Synthego

Mammoth Biosciences

Inscripta, Inc.

Cibus

Beam Therapeutics

PlanteditVertex Pharmaceuticals Incorporated

Hera Biolabs

Origene Technologies, Inc.

Recombinetics, Inc.

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Global $4.88 Bn CRISPR & Cas Genes Market to 2027: Opportunities in the Expanding Gene & Cell Therapy Area & Government Fund In Genomic R&D - Yahoo...

With 75 percent of current S&P 500 companies expected to disappear until 2027, according to research by McKinsey. The only constant in our world is changing, the pace of change has been expediting significantly over the past years, fueled by huge investments in technology and science, easier access to truly global markets, and a general cultural shift towards innovation among other key drivers are helping to rise of CRISPR Genome Editing market.

This CRISPR Genome Editing research study presented by AMR aims at providing facts necessary to understand market dynamics and to capitalize on them, presenting the CRISPR Genome Editing research study with 118 number of pages and global key trends that can help clients in their CRISPR Genome Editing business to achieve more Goal, Desired Growth with making new business strategies to gain in the market.

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CRISPR Genome Editing Market Research study offers a comprehensive evaluation of the Market and comprises a future trend, current growth factors, focused opinions, details, and industry certified market data, sales, revenue, production and forecast and more.

CRISPR Genome Editing Market competitive landscape and Profile of Market Leaders

This market research study includes compiling intelligence data and structured and professional company profiles which will benefit to analyze competitors, a potential takeover target and Identifying leading market players across markets and find potential target markets.

Moreover, this market report provides in-depth analyses of CRISPR Genome Editing market and display significant data regarding key companies, consumers, market developments, and the competitive landscape focusing Editas Medicine, CRISPR Therapeutics, Horizon Discovery, Sigma-Aldrich, Genscript, Sangamo Biosciences, Lonza Group, Integrated DNA Technologies, New England Biolabs, Origene Technologies, Transposagen Biopharmaceuticals, Thermo Fisher Scientific, Caribou Biosciences, Precision Biosciences, Cellectis, Intellia Therapeutics.

CRISPR Genome Editing Market Segmentation by Product Type and Application

The CRISPR Genome Editing report focuses on consumers behaviors at a specific requirement by end-use, usage pattern providing more insights about its competitive landscape such as By Product Type(Genetic Engineering, Gene Library, Human Stem Cells) and Application(Biotechnology Companies, Pharmaceutical Companies).

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CRISPR Genome Editing Market Segmentation by Regions

This market research study presents dive deep into CRISPR Genome Editing and turn complex insights into ready-to-use analyses for you.

The research report is about the economic effects of the CRISPR Genome Editing market. This report reveals that there more economic benefits to North America, Europe, Asia Pacific (includes Asia & Oceania separately), the Middle East and Africa (MEA), and Latin America region, as well as other positive commercial and social effects.

Key Points Covered in CRISPR Genome Editing Market Report:

13.Current and historical revenues

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Market trends and outlook coupled with factors driving and restraining the growth of the CRISPR Genome Editing market - The Daily Chronicle

GlobalCRISPR and CAS Gene MarketResearch Report is a resource, which provides current as well as upcoming technical and financial details of the industry to 2027. This report gives you so important and essentials data of Market size, share, trends, Growth, applications, forecast and cost analysis. Delivery development in North America, China, Europe, and South East Asia, Japan as well as in the Globe. The report proves to be indispensable when it comes to market definition, classifications, applications and engagements.

The market report also computes the market size and revenue generated from the sales. The industry analysis report presents the key statistics on the market status of global and regional manufacturers and also acts as a valuable source of leadership and direction. What is more, the CRISPR and CAS Gene market report analyses and provides historic data along with the current performance of the market.

Get a Free Sample Copy of the CRISPR and CAS Gene Market Report with Latest Industry Trends @https://www.coherentmarketinsights.com/insight/request-sample/2598

Global CRISPR and CAS Gene Market competition by Top Key Players: Caribou Biosciences Inc., CRISPR Therapeutics, Mirus Bio LLC, Editas Medicine, Takara Bio Inc., Synthego, Thermo Fisher Scientific, Inc., GenScript, Addgene, Merck KGaA (Sigma-Aldrich), Integrated DNA Technologies, Inc., Transposagen Biopharmaceuticals, Inc., OriGene Technologies, Inc., New England Biolabs, Dharmacon, Cellecta, Inc., Agilent Technologies, and Applied StemCell, Inc.

CRISPR and CAS Gene Market section by Region:

Segmentation: The report has been separated into different categories, such as product type, application, end user, and region. Every segment is evaluated based on the CAGR, share and growth potential. In the regional analysis, the report highlights the prospective region, which should generate opportunities in the global CRISPR and CAS Gene market in the years to come. This segmented analysis will surely prove to be a useful tool for readers, stakeholders and market participants to get a full picture of the CRISPR and CAS Gene global market and its growth potential in the years to come.

The CRISPR and CAS Gene Market report offers a plethora of insights which include:

Changing consumption patterns among individuals globally.

Historical and future progress of the global CRISPR and CAS Gene market.

Region-wise and country-wise segmentation of the CRISPR and CAS Gene market to understand the revenue, and growth lookout in these areas.

Accurate Year-on-Year growth of the global CRISPR and CAS Gene market.

Important trends, including proprietary technologies, ecological conservation, and globalization affecting the global CRISPR and CAS Gene market.

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Important Information that can be extracted from the Report:

Assessment of the COVID-19 impact on the growth of the CRISPR and CAS Gene Market

Successful market entry strategies formulated by emerging market players

Pricing and marketing strategies adopted by established market players

Country-wise assessment of the CRISPR and CAS Gene Market in key regions

Year-on-Year growth of each market segment over the forecast period 2026

The CRISPR and CAS Gene Market report considers the following years to predict market growth:

Historic Year: 2014 2018

Base Year: 2019

Estimated Year: 2020

Forecast Year: 2020 2027

The Global CRISPR and CAS Gene Market is displayed in 13 Chapters:

Chapter 1: Market Overview, Drivers, Restraints and Opportunities

Chapter 2: Market Competition by Manufacturers

Chapter 3: Production by Regions

Chapter 4: Consumption by Regions

Chapter 5: Production, By Types, Revenue and Market share by Types

Chapter 6: Consumption, By Applications, Market share (%) and Growth Rate by Applications

Chapter 7: Complete profiling and analysis of Manufacturers

Chapter 8: Manufacturing cost analysis, Raw materials analysis, Region-wise manufacturing expenses

Chapter 9: Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10: Marketing Strategy Analysis, Distributors/Traders

Chapter 11: Market Effect Factors Analysis

Chapter 12: Market Forecast

Chapter 13: CRISPR and CAS Gene Research Findings and Conclusion, Appendix, methodology and data source

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CRISPR and CAS Gene Market Growth Analysis with Top Players Caribou Biosciences Inc., CRISPR Therapeutics, Mirus Bio LLC, Editas Medicine, Takara Bio...

Final Report will add the analysis of the impact of COVID-19 on this industry.

Global Crispr And Crispr-Associated (Cas) Genes Market Research Report 2020-2025 is a historical overview and in-depth study on the current & future market of the Crispr And Crispr-Associated (Cas) Genes industry. The report represents a basic overview of the Crispr And Crispr-Associated (Cas) Genes market share, competitor segment with a basic introduction of key vendors, top regions, product types, and end industries. This report gives a historical overview of the Crispr And Crispr-Associated (Cas) Genes market trends, growth, revenue, capacity, cost structure, and key drivers analysis.

Get a Sample PDF of report @ https://www.industryresearch.biz/enquiry/request-sample/16203415

In Chapter 2.4 of the report, we share our perspectives for the impact of COVID-19 from the long and short term.In chapter 3.4, we provide the influence of the crisis on the industry chain, especially for marketing channels.In chapters 8-13, we update the timely industry economic revitalization plan of the country-wise government.

The report mainly studies the Crispr And Crispr-Associated (Cas) Genes market size, recent trends and development status, as well as investment opportunities, market dynamics (such as driving factors, restraining factors), and industry news (like mergers, acquisitions, and investments). Technological innovation and advancement will further optimize the performance of the product, making it more widely used in downstream applications. Moreover, Porters Five Forces Analysis (potential entrants, suppliers, substitutes, buyers, industry competitors) provides crucial information for knowing the Crispr And Crispr-Associated (Cas) Genes market.

TO UNDERSTAND HOW COVID-19 IMPACT IS COVERED IN THIS REPORT

Key players in the global Crispr And Crispr-Associated (Cas) Genes market covered in Chapter 5:

Global Crispr And Crispr-Associated (Cas) Genes Industry 2020 Market Research Report also provides exclusive vital statistics, data, information, trends and competitive landscape details in this niche sector.

Top Countries Data Covered in Crispr And Crispr-Associated (Cas) Genes Market Report are United States, Canada, Mexico, Germany, UK, France, Italy, Spain, Russia, China, Japan, South Korea, Australia, India, Southeast Asia, Saudi Arabia, UAE, Egypt, Nigeria, South Africa, Brazil, Argentina, Columbia, Chile, and Others

Scope of the Crispr And Crispr-Associated (Cas) Genes Market Report:

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Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2015-2025) of the following regions are covered in Chapter 8-13:

In Chapter 6, on the basis of types, the Crispr And Crispr-Associated (Cas) Genes market from 2015 to 2025 is primarily split into:

In Chapter 7, on the basis of applications, the Crispr And Crispr-Associated (Cas) Genes market from 2015 to 2025 covers:

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Global Crispr And Crispr-Associated (Cas) Genes Market providing information such as company profiles, product picture and specification, capacity, production, price, cost, revenue and contact information. Upstream raw materials and equipment and downstream demand analysis are also carried out. The Global Crispr And Crispr-Associated (Cas) Genes market development trends and marketing channels are analyzed. Finally, the feasibility of new investment projects is assessed and overall research conclusions offered.

Some of the key questions answered in this report:

With tables and figures helping analyze worldwide Global Crispr And Crispr-Associated (Cas) Genes market growth factors, this research provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market.

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Years considered for this report:

Key Points from TOC:

1 Market Overview1.1 Product Definition and Market Characteristics1.2 Global Crispr And Crispr-Associated (Cas) Genes Market Size1.3 Market Segmentation1.4 Global Macroeconomic Analysis1.5 SWOT Analysis

2. Market Dynamics2.1 Market Drivers2.2 Market Constraints and Challenges2.3 Emerging Market Trends2.4 Impact of COVID-192.4.1 Short-term Impact2.4.2 Long-term Impact

3 Associated Industry Assessment3.1 Supply Chain Analysis3.2 Industry Active Participants3.2.1 Suppliers of Raw Materials3.2.2 Key Distributors/Retailers3.3 Alternative Analysis3.4 The Impact of Covid-19 From the Perspective of Industry Chain

4 Market Competitive Landscape4.1 Industry Leading Players4.2 Industry News4.2.1 Key Product Launch News4.2.2 M&A and Expansion Plans

5 Analysis of Leading Companies5.1 Company 15.1.1 Company 1 Company Profile5.1.2 Company 1 Business Overview5.1.3 Company 1 Crispr And Crispr-Associated (Cas) Genes Sales, Revenue, Average Selling Price and Gross Margin (2015-2020)5.1.4 Company 1 Crispr And Crispr-Associated (Cas) Genes Products Introduction

5.2 Company 25.2.1 Company 2 Company Profile5.2.2 Company 2 Business Overview5.2.3 Company 2 Crispr And Crispr-Associated (Cas) Genes Sales, Revenue, Average Selling Price and Gross Margin (2015-2020)5.2.4 Company 2 Crispr And Crispr-Associated (Cas) Genes Products Introduction

5.3 Company 35.3.1 Company 3 Company Profile5.3.2 Company 3 Business Overview5.3.3 Company 3 Crispr And Crispr-Associated (Cas) Genes Sales, Revenue, Average Selling Price and Gross Margin (2015-2020)5.3.4 Company 3 Crispr And Crispr-Associated (Cas) Genes Products Introduction

5.4 Company 45.4.1 Company 4 Company Profile5.4.2 Company 4 Business Overview5.4.3 Company 4 Crispr And Crispr-Associated (Cas) Genes Sales, Revenue, Average Selling Price and Gross Margin (2015-2020)5.4.4 Company 4 Crispr And Crispr-Associated (Cas) Genes Products Introduction

6 Market Analysis and Forecast, By Product Types6.1 Global Crispr And Crispr-Associated (Cas) Genes Sales, Revenue and Market Share by Types (2015-2020)6.2 Global Crispr And Crispr-Associated (Cas) Genes Market Forecast by Types (2020-2025)6.3 Global Crispr And Crispr-Associated (Cas) Genes Sales, Price and Growth Rate by Types (2015-2020)6.4 Global Crispr And Crispr-Associated (Cas) Genes Market Revenue and Sales Forecast, by Types (2020-2025)

7 Market Analysis and Forecast, By Applications7.1 Global Crispr And Crispr-Associated (Cas) Genes Sales, Revenue and Market Share by Applications (2015-2020)7.2 Global Crispr And Crispr-Associated (Cas) Genes Market Forecast by Applications (2020-2025)7.3 Global Revenue, Sales and Growth Rate by Applications (2015-2020)7.4 Global Crispr And Crispr-Associated (Cas) Genes Market Revenue and Sales Forecast, by Applications (2020-2025)

8 Market Analysis and Forecast, By Regions8.1 Global Crispr And Crispr-Associated (Cas) Genes Sales by Regions (2015-2020)8.2 Global Crispr And Crispr-Associated (Cas) Genes Market Revenue by Regions (2015-2020)8.3 Global Crispr And Crispr-Associated (Cas) Genes Market Forecast by Regions (2020-2025)Continued.

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Crispr And Crispr-Associated (Cas) Genes Market Size 2020 Explosive Factors of Revenue By Industry Statistics, Progression Status, Emerging Demands,...

The Global CRISPR Market research report presentation is a decisive gateway into unfurling various significant events and developments prevalent in the market spectrum that collectively usher into a flourishing growth outlook in the global CRISPR market. Optimum research hint that the aforementioned market is likely to register a robust growth, reaching over xx million USD through the forecast span, 2020-26, maintaining a steady CAGR valuation of xx% throughout.

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According to meticulous primary and secondary research endeavors on the part of our in-house research experts, the global CRISPR market is likely to emerge from the catastrophic after-effects of the unprecedented COVID-19 pandemic that has severely crippled businesses and paralyzed industries globally. However, post dedicated research initiatives, research suggests an optimistic comeback, suggesting healthy growth at the end of 2026.

Key Manufacturers Analysis:

Intellia Therapeutics, Inc.Transposagen Biopharmaceuticals, Inc.GenScript Biotech CorporationThermo Fisher Scientific, Inc.GE Healthcare Dharmacon IncIntegrated DNA Technologies, Inc.CRISPR TherapeuticsAddgene

The report segregates the market into various segments such as type and application that continue to remain prominent growth influencers in global CRISPR market. To evoke resilient market specific growth factors that constantly shape growth prospects in global CRISPR market, this ardent research report sheds light on market segmentation based on which this research presentation aims to equip report readers with versatile understanding about potential market segments that encourage sustainable revenue generation despite stringent competition.

CRISPR Market Analysis by Types:

Design ToolsPlasmid and VectorCas9 and g-RNADelivery System Products

CRISPR Market Analysis by Applications:

Genome EditingGenetic EngineeringGMO and CropsHuman Stem CellsOthers

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Global CRISPR Market: Regional Review

1. The report is designed to adequately highlight a detailed matrix of region-wise and country-specific classification, depicting volume specific production details as well as refers to consumption patterns, further proceeding with minute details related to revenue generation and growth progress throughout the growth tenure, 2020-26.2. Additionally, in the report on global CRISPR market, research initiatives have suggested significant developments encompassing significant developments across diverse regions as well as countries that enable successful growth prognosis through the forecast span, 2020-26.3. The report draws specific references of country-specific developments across both emerging and developed economies alike that collectively contribute towards uncompromised and healthy growth trail in the global CRISPR market throughout the forecast span.4. The CRISPR market report is systematically classified into graphs, charts and statistical presentation to mimic steady growth.

Report Investment Guide:

1. This meticulous research documentation endeavors to offer extensive overview of the industry and studies the CRISPR market at a multi-faceted perspective.2. The report in order to uphold real time market status is hovering mainly across important areas such as real time market growth status to encourage accurate market specific decisions.3. The CRISPR report is focusing specifically across a range of key development areas such as dynamic segmentation, cross sectional analysis of the target market.4. This elaborate report also is a ready-to-go market specific document encompassing regional overview, opportunity mapping, and competition analysis.

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Global CRISPR Market 2020 Size, Growth Drivers, SWOT Analysis, 2026 Key Companies Overview- Intellia Therapeutics, Inc., Transposagen...

A2Z Market Research announces the release of the Gene Editing Tools Market research report. The market is predicted to grow at a healthy pace in the coming years. Gene Editing Tools Market 2020 research report presents an analysis of market size, share, and growth, trends, cost structure, statistical and comprehensive data of the global market. The Market report offers remarkable data regarding the industrys growth parameters, the current state of the market in terms of analysis of possible economic situations, and macroeconomic analysis.

Gene Editing is a type of genetic engineering in which DNA is inserted, deleted, modified, or replaced in the genome of a living organism. .This process requires specialized tools to be carried out and is generally undertaken in different labs with the help of engineered nucleases. The global gene-editing tool market is expected to register significant growth in the near future attributed to the rise in the prevalence of cancer and genetic disorders such as sickle cell diseases, Alzheimers disease, and others, for which there are close to none or very limited therapy options available, along with other genetic and metabolic disorders such as diabetes, obesity, and others. Gene Editing Tools Market is growing at a CAGR of +18% during the forecast period 2020-2026.

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The top companies in this report include:

Thermofisher Scientific, CRISPR Therapeutics, Editas Medicine, NHGRI, Intellia Therapeutics, Merck KGaA, and others.

This report provides an in-depth review of the current state of the Gene Editing Tools market, daring its growth and all other essential elements in all of the major markets of the county.It presents a gigantic amount of market data, compiled using myriad primary and secondary research practices.The data in this report has been reduced on a business basis using various systematic methods.

For a comprehensive analysis, the Gene Editing Tools market is segmented by product type, region, and application. Due to its regional focus, the market is alien to North America, Europe, Asia-Pacific, the Middle East, and Africa as well as Latin America. Major companies are working on distributing their products and services across different regions. In addition, procurements and associations from some of the leading organizations. All of the factors intended to drive the global marketplace are examined in depth.

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This report gives an in-depth and broad understanding of the Gene Editing Tools Market. With exact data cover all key features of the current market, this report offers widespread data from leading companies. Appreciative of the market state by amenability of correct historical data regarding each and every sector for the forecast period is mentioned. Driving forces, restraints, and opportunities are given to help give an improved picture of this market investment for the forecast period of 2020 to 2027.

Key Factors Impacting Market Growth:

o Convergence of data with accuracy and high speedo Rising demand for efficient computingo Increasing opportunities through improved research, computation, and data analysis performanceso High price and data security issues

The main questions answered in the report are:

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Gene Editing Tools Market to Witness a Pronounce Growth During 2020-2027 | Top Manufacturers: Thermofisher Scientific, CRISPR Therapeutics, Editas...

CRISPR Technology Industry 2020 Market Research Report A new report added by DeepResearchReports.com to its research database. CRISPR Technology Market is segmented by Regions/Countries. All the key market aspects that influence the CRISPR Technology market currently and will have an impact on it have been assessed and propounded in the CRISPR Technology market research status and development trends reviewed in the new report.

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The economical unrest across the globe due to Covid19 pandemic has affected different industries. Several businesses have gone through revenue hassles. It has impacted many product launches and marketing strategies to an extent that numerous industries and global businesses were compelled to either cease, halt or even shut their operations. Now, when businesses are trying to refurbish their existence across the globe, a ready referral guide in the form of market research report can help in providing a direction with the useful information about the market dynamics.

Next, learn how to build the strategy and business case to implement. Learn about CRISPR Technology market and how it can provide value to your business. In this market, you will find the competitive scenario of the major market players focusing on their sales revenue, customer demands, company profile, import/export scenario, business strategies that will help the emerging market segments in making major business decisions. This report also studies the global market competition landscape, market drivers and trends, opportunities and challenges, risks and entry barriers, sales channels, distributors and Porters Five Forces Analysis.

About the report:

The new tactics of CRISPR Technology market report offers a comprehensive market breakdown on the basis of value, volume, CAGR, and Y-o-Y growth. For business robust expansion, the report suggests new tools and technology development will drive to boom in the near future by 2026. The CRISPR Technology market report provides a comprehensive outline of Invention, Industry Requirement, technology and production analysis considering major factors such as revenue, investments and business growth.

This report for CRISPR Technology Market discovers diverse topics such as regional market scope, product-market various applications, market size according to a specific product, CRISPR Technology sales and revenue by region, manufacturing cost analysis, industrial chain, market effect factors Analysis, and more.

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Table of Contents

Chapter 1 CRISPR Technology Market OverviewChapter 2 Global CRISPR Technology Competition by Players/Suppliers, Type and ApplicationChapter 3 United States CRISPR Technology (Volume, Value and Sales Price)Chapter 4 China CRISPR Technology (Volume, Value and Sales Price)Chapter 5- Europe CRISPR Technology (Volume, Value and Sales Price)Chapter 6 Japan CRISPR Technology (Volume, Value and Sales Price)Chapter 7 Southeast Asia CRISPR Technology (Volume, Value and Sales Price)Chapter 8 India CRISPR Technology (Volume, Value and Sales Price)Chapter 9 Global CRISPR Technology Players/Suppliers Profiles and Sales DataChapter 10 CRISPR Technology Manufacturing Cost AnalysisChapter 11 Industrial Chain, Sourcing Strategy and Downstream BuyersChapter 12 Marketing Strategy Analysis, Distributors/TradersChapter 13 Market Effect Factors AnalysisChapter 14 Global CRISPR Technology Market Forecast (2020-2026)Chapter 15 Research Findings and ConclusionChapter 16 Appendix

Key Questions Answered in this Report:

What is the market size of the CRISPR Technologyindustry?This report covers the historical market size of the industry (2013-2019), and forecasts for 2020 and the next 5 years. Market size includes the total revenues of companies.

What is the outlook for the CRISPR Technologyindustry?This report has over a dozen market forecasts (2020 and the next 5 years) on the industry, including total sales, a number of companies, attractive investment opportunities, operating expenses, and others.

What industry analysis/data exists for the CRISPR Technologyindustry?This report covers key segments and sub-segments, key drivers, restraints, opportunities, and challenges in the market and how they are expected to impact the CRISPR Technologyindustry. Take a look at the table of contents below to see the scope of analysis and data on the industry.

How many companies are in the CRISPR Technologyindustry?This report analyzes the historical and forecasted number of companies, locations in the industry, and breaks them down by company size over time. The report also provides company rank against its competitors with respect to revenue, profit comparison, operational efficiency, cost competitiveness, and market capitalization.

What are the financial metrics for the industry?This report covers many financial metrics for the industry including profitability, Market value- chain, and key trends impacting every node with reference to the companys growth, revenue, return on sales, etc.

What are the most important benchmarks for the CRISPR Technologyindustry?Some of the most important benchmarks for the industry include sales growth, productivity (revenue), operating expense breakdown, span of control, organizational make-up. All of which youll find in this market report.

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Covid-19 Impact on CRISPR Technology Market to Witness Huge Growth by 2026: Future Development and Top Manufacturers Analysis - Verdant News

Fact.MR has recently added a new research report on the global CRISPR and Cas Genes market size to its repository. This report aims to help readers in understanding key technologies as well as product developments in this market during the forecast period of 2020 to 2026. Analysts at Fact.MR highlight that the global CRISPR and Cas Genes market will show growth at a prominent CAGR of 21.2% during the period of analysis.

This report intends to offer an in-depth analysis of various important aspects such as opportunities, drivers, challenges, and restraints of the global CRISPR and Cas Genes market. In addition to this, it provides detailed data on various key players working in this market together with important data on their diverse business strategies to maintain their prominent market position.

The overall share, volume, and other additional important information of important players is also precisely presented in the latest report on the global CRISPR and Cas Genes market. Apart from this, readers get a clear idea about emerging players and the competitive landscape of the market for CRISPR and Cas Genes during the forecast period of 2020 to 2026. This aside, the report covers important data on strengths, weaknesses, and threats of all important vendors in the global CRISPR and Cas Genes market.

The report on the global CRISPR and Cas Genes market offers detailed analysis on various activities that impact on the growth of this market. Thus, the report includes reliable data on partnerships, new product launches, mergers, and acquisitions occurring in the global CRISPR and Cas Genes market during the period of analysis.

To know more about this market trends, drivers, regional analysis request a sample @ https://www.factmr.com/connectus/sample?flag=S&rep_id=4823

Fact.MRs latest report delivers a complete study of the impact of COVID-19 on the CRISPR and Cas Genes market in the present situation. At the same time, it gives readers an idea about the potential effects of the COVID-19 pandemic during the forecast period of 2020 to 2026. The report gives region-wise as well as country-wise data related to the impact of COVID-19 on the growth of the global CRISPR and Cas Genes market. Apart from this, the report talks about diverse strategies executed by industry leaders to deal with this critical situation. This information is intended to assist all key entities while handling critical situations and continuing the work successfully during this pandemic.

The global CRISPR and Cas Genes market study delivers data on the present market situation on regional as well as global levels. In addition to this, it offers forecasts on market development during the assessment period. To offer this top-notch study, the analysts at Fact.MR has utilized diverse industrial as well as digitalization tools. These tools have helped them to present futuristic insights to readers on the global CRISPR and Cas Genes market. In addition to this, the report covers a basic overview of the CRISPR and Cas Genes market and its taxonomy. This data helps in improving the overall reader experience.

Depending on product type, the CRISPR and Cas Genes market report is divided into the following segments:

Based on end-use, the CRISPR and Cas Genes market report is bifurcated into:

Major players profiled in the report on the global CRISPR and Cas Genes market include:

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Key regions covered in the global CRISPR and Cas Genes market report are:

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CRISPR and Cas Genes Market to Witness Positive Growth owing to Outbreak of COVID-19, Projects Fact.MR - The Cloud Tribune

Researchers say they have potentially developed a new, more convenient tests for the coronavirus that uses the genetic technology known as CRISPR and could produce results in less than an hour.

The researchers at Massachusetts Institute of Technology and the Broad Institute say the new test, known as STOPCovid, was found to be as accurate as the current molecular test known as aPCR test. They tested 400 patient samples and the new test was found to detect 93% of positive cases.Their findings were published in theNew England Journal of Medicine this week.

"We found that we could essentially match the gold standard," said Jonathan Gootenberg, a McGovern Institute fellow at MIT. "This could be done very rapidly and without expensive instrumentation."

Omar Abudayyeh, another MIT McGovern fellow working on the research, said the test is sensitive and can detect even a low amount of the virus. He said the testing would be most useful as a regular diagnostic tool that would be repeatedly test patients.

"If you're cheap enough and easy enough to run every day, you're going to capture someone when their viral load is high enough that you'll be able to take them out into quarantine before they can spread," Abudayyeh said.

The researchers useda CRISPR-based process to concentrate viral genetic material in a test sample. They said that would eliminate the need for the testing materials that are currently in short supply because of the pandemic, and a commercial lab would not have to process the results.

"Using these technologies will really allow for much more rapid testing down from days to sometimes less than an hour," said MIT McGovern fellow Jonathan Gootenberg. "That would enable a drastic change in how the tracing and handling of the pandemic is done."

They hope to further simplify the test so it can be used by patients at home. Gootenberg said they are working with clinical test developers to have this type of test on the market in a few months.

The researchers worked with other scientists at the University of Washington, Fred Hutchinson Cancer Research Center, Brigham and Women's Hospital, and the Ragon Institute.

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MIT, Harvard Researchers Say They're Close To A New Rapid COVID Test - WBUR

An opioid-blocking vaccine could spare many people a lifetime of drug addiction, if and when its developed. COVID-19 exposed Africas inability to mitigate a pandemic; the silver lining is that it focused a spotlight on neglected tropical diseases that plague countries on the continent. Researchers in Israel are using CRISPR gene editing to improve cannabis production, helping ensure a stable supply of medical marijuana for patients all over the world.

Podcast: Play in new window | Download

Subscribe: Apple Podcasts | Android |

Join geneticist Kevin Folta and GLP editor Cameron English on this episode of Science Facts and Fallacies as they break down these latest news stories:

A vaccine for opioid addiction could spare many people a lifetime of drug decadency, and all the tragic side effects that come with it. Three candidate vaccines are currently undergoing clinical trials, but a new study suggests that such a drug may not be effective when its most needed, because the bodys immune system may counteract the vaccines effect.

Drug policy reform advocates have also challenged the ethics of developing an opioid vaccine. Why, they ask, should the federal government invest money in a speculative vaccine when it could fund proven harm-reduction strategies that ultimately reduce drug use? Moreover, could people convicted of drug offenses be required to get an opioid immunization, and who would pay for it?

Plagued by conflict, corrupt governments, poverty and lacking health care infrastructure, Africa was woefully unprepared to combat the coronavirus that rapidly made its way across the globe early in 2020. COVID-19 didnt strike Africa as hard as it did other parts of the world, fortunately enough, but it has highlighted a critical and often overlooked problem in Africa: neglected tropical diseases (NTDs).

As the name implies, these conditions get little attention from the international medical community, because they primarily afflict people in poor countries. A small contingency of infectious disease experts and philanthropies is committed to helping governments tackle the problem, however Africa ultimately has to reform its political institutions and invest in the health care infrastructure that can prevent and treat NTDs.

Researchers are improving all sorts of crops with CRISPR gene editing: everything from wheat, tomatoes and applesto cannabis. A biotech startup in Israel is utilizing the powerful new breeding technique to develop disease-resistant marijuana that can be easily grown from seed (instead of cloned) under greenhouse conditions, the goal being to produce a more stable supply of medical-grade cannabis for patients all over the world.

Subscribe to the Science Facts and Fallacies Podcast on iTunes and Spotify.

Kevin M. Folta is a professor in the Horticultural Sciences Department at the University of Florida. Follow Professor Folta on Twitter @kevinfolta

Cameron J. English is the GLPs managing editor. BIO. Follow him on Twitter @camjenglish

Continued here:
Podcast: CRISPR-edited weed; opioid addiction vaccine; Africa's neglected diseases - Genetic Literacy Project

CRISPR Therapeutics (NASDAQ:CRSP) has had a great run on the share market with its stock up by a significant 19% over the last three months. However, we decided to pay attention to the companys fundamentals which dont appear to give a clear sign about the companys financial health. Specifically, we decided to study CRISPR Therapeutics ROE in this article.

Return on equity or ROE is an important factor to be considered by a shareholder because it tells them how effectively their capital is being reinvested. Simply put, it is used to assess the profitability of a company in relation to its equity capital.

View our latest analysis for CRISPR Therapeutics

The formula for return on equity is:

Return on Equity = Net Profit (from continuing operations) Shareholders Equity

So, based on the above formula, the ROE for CRISPR Therapeutics is:

2.1% = US$20m US$911m (Based on the trailing twelve months to June 2020).

The return is the income the business earned over the last year. So, this means that for every $1 of its shareholders investments, the company generates a profit of $0.02.

Thus far, we have learned that ROE measures how efficiently a company is generating its profits. Based on how much of its profits the company chooses to reinvest or retain, we are then able to evaluate a companys future ability to generate profits. Assuming everything else remains unchanged, the higher the ROE and profit retention, the higher the growth rate of a company compared to companies that dont necessarily bear these characteristics.

It is quite clear that CRISPR Therapeutics ROE is rather low. Even compared to the average industry ROE of 14%, the companys ROE is quite dismal. Hence, the flat earnings seen by CRISPR Therapeutics over the past five years could probably be the result of it having a lower ROE.

Next, on comparing with the industry net income growth, we found that CRISPR Therapeutics reported growth was lower than the industry growth of 27% in the same period, which is not something we like to see.

The basis for attaching value to a company is, to a great extent, tied to its earnings growth. What investors need to determine next is if the expected earnings growth, or the lack of it, is already built into the share price. Doing so will help them establish if the stocks future looks promising or ominous. Is CRISPR Therapeutics fairly valued compared to other companies? These 3 valuation measures might help you decide.

CRISPR Therapeutics doesnt pay any dividend, meaning that potentially all of its profits are being reinvested in the business. However, this doesnt explain why the company hasnt seen any growth. So there could be some other explanations in that regard. For instance, the companys business may be deteriorating.

Overall, we have mixed feelings about CRISPR Therapeutics. Even though it appears to be retaining most of its profits, given the low ROE, investors may not be benefitting from all that reinvestment after all. The low earnings growth suggests our theory correct. That being so, the latest analyst forecasts show that the company will continue to see an expansion in its earnings. To know more about the companys future earnings growth forecasts take a look at this free report on analyst forecasts for the company to find out more.

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This article by Simply Wall St is general in nature. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned. *Interactive Brokers Rated Lowest Cost Broker by StockBrokers.com Annual Online Review 2020

Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team@simplywallst.com.

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CRISPR Therapeutics AGs (NASDAQ:CRSP) Stock Is Rallying But Financials Look Ambiguous: Will The Momentum Continue? - Simply Wall St

MONDAY 14th September

August transfers from Alibaba show Ant Financial inheriting up to one quarter of the e-commerce giants US portfolio, making it a patent power in its own right. Read more here

The Supreme People's Court hasgranted Chinas first anti-suit injunction in a patent case, ordering Conversant not to enforce aGerman sales ban it won against Huawei in August. Read more here

In extraordinary step, DOJ antitrust head Makan Delrahim calls onthe IEEE to consider changes tolicensing rules which have been bitterly opposed by many top SEP owners. Read more here

TUESDAY 15th September

The Broad Institute has been handed a significant win by the PTAB in its ongoing CRISPR patent battle with UCAL Berkeley. Read more here

Confronting critical challenges, Taiwan's tech companies must find a way to create patent value - IAMspeaks with IP leaders from Foxconn, AU Optronics and others. Read more here

Ireland-based Solas OLED flexes its financial muscle and accuses group of tech giants of infringing patents that originated with Casio. Read more here

WEDNESDAY 16th September

The High Court of Australia could overturn a 112-year-old doctrine of patent exhaustion precedent in a much-awaited ruling that will havebroad commercial implications. Read more here

Speaking at IPBC Connect, the EPO and USPTO leaders say covid-induced changes are here to stay and warn of decreased user engagement caused by the pandemic. Read more here

Efficient infringement is an anathema to Apple, says company CEO Cook in letter to Congressman that also praises the eBay decision and calls for further study of the plague of PAEs. Read more here

THURSDAY 17th September

Ninestar, part of a formidable stable of Chinese companies focused on printing technology, is back in Canons crosshairs after a successful defence against the Japanese giant at the ITC. Read more here

There is growing pressure on US federal agencies and government departments to enforce the patents they own, especially in the life sciences arena. Read more here

The covered business method programme at the PTAB has ended, but efforts to extend it are now being made as influential banking group eyes broader conversation about patents. Read more here

FRIDAY 18th September

Settlements worth hundreds of millions of dollars with the likes of Apple and Samsung have put Korean university KAIST in the licensing big leagues. Read more here

The technological and geographic scope of InterDigitals patent portfolio means new chief licensing officer Eeva Hakoranta has a lot to play with. Read more here

Companies implementing 5G standards must consider the licensing implications of a large chunk of patents that currently lie under the radar. Read more here

SATURDAY 19th September

In this weeks Saturday Opinion, Scott Cleland argues that Googles most effective revenue growth engines have all depended, to an extent at least, on infringing IP owned by leading competitors. Read more here

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China's first anti-suit injunction; Apple CEO rejects efficient infringement; CRISPR patent battle latest; EPO and USPTO heads' covid warning; CBM...

This article was originally published here

Nat Commun. 2020 Sep 18;11(1):4711. doi: 10.1038/s41467-020-18575-6.

ABSTRACT

The recent outbreak of novel coronavirus (SARS-CoV-2) causing COVID-19 disease spreads rapidly in the world. Rapid and early detection of SARS-CoV-2 facilitates early intervention and prevents the disease spread. Here, we present an All-In-One Dual CRISPR-Cas12a (AIOD-CRISPR) assay for one-pot, ultrasensitive, and visual SARS-CoV-2 detection. By targeting SARS-CoV-2s nucleoprotein gene, two CRISPR RNAs without protospacer adjacent motif (PAM) site limitation are introduced to develop the AIOD-CRISPR assay and detect the nucleic acids with a sensitivity of few copies. We validate the assay by using COVID-19 clinical swab samples and obtain consistent results with RT-PCR assay. Furthermore, a low-cost hand warmer (~$0.3) is used as an incubator of the AIOD-CRISPR assay to detect clinical samples within 20 min, enabling an instrument-free, visual SARS-CoV-2 detection at the point of care. Thus, our method has the significant potential to provide a rapid, sensitive, one-pot point-of-care assay for SARS-CoV-2.

PMID:32948757 | DOI:10.1038/s41467-020-18575-6

Originally posted here:
Ultrasensitive and visual detection of SARS-CoV-2 using all-in-one dual CRISPR-Cas12a assay - DocWire News

ReportsnReports added Latest Emerging Gene Therapies Market Research Report offers crucial data on numerous market situations, for example, ability improvement elements, elements controlling the advancement, market possibilities, and risks to the global market. Also, the report widely facilities round competitive evaluation of Emerging Gene Therapies Market. The competitive evaluation section includes key producers, recent players, providers, market strategies, ability chances, operation panorama, and evaluation of the traits of the Emerging Gene Therapies Market.

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AmgenGilead SciencesNovartisSanofiGlaxoSmithKlinePfizer

Emerging Gene Therapies Market Report provides a comprehensive overview of the emerging gene therapy market. The report discusses gene therapy and the technology behind gene editing, outlining the advantages, limitations and current evidence for the platforms under development. The report discusses relevant clinical studies targeting specific therapeutic indications and highlights examples of current challenges within the field, with a focus on therapies that target the eye, liver, and blood.

Additionally, the report provides a background to the CRISPR patent litigation, a key factor within the gene editing company landscape. It provides profiles of six companies developing gene editing platforms, considers the gene therapy interests of the main pharmaceutical companies, and discusses current regulatory trends in the development of gene therapies.

Emerging Gene Therapies Market Report explores how emerging gene editing products will compete with established products, their relative competitive strengths, and upcoming value inflection points within the field.

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Table of Contents1.1 List of Tables 71.2 List of Figures 82 Introduction 102.1 Gene Therapy Definitions 102.2 Report Coverage the Emerging Gene Therapy Pipeline 112.3 History of Gene Therapy 122.4 Limitations of Gene Transfer 132.5 The Development of Targeted Gene Editing 132.6 Overview of Gene Editing Platforms 132.6.1 Zinc Fingers (1996) 132.6.2 Transcription Activator-Like Effectors (2011) 142.6.3 The CRISPR/Cas System (2013) 152.6.4 Effectors for Targeting Domains 192.6.5 Comparison of Gene Editing Systems 192.6.6 Summary of Gene Editing Systems 192.7 Overview of In Vivo Gene Therapy 212.7.1 Editing is Dependent on Cell Type, Stage, and Repair Pathway 212.7.2 Delivery 212.7.3 Emerging Safety Concerns with Editing Platforms 242.7.4 Editing Products are Reliant on the Target Cells Cycle Stage and DNA Repair Machinery 272.7.5 Advantages of Gene Editing over Gene Transfer 282.7.6 Integration into Safe Harbor Sites 282.7.7 The Increasing Complexity of Gene Therapy 302.7.8 Summary of In Vivo Gene Therapy 313 Gene Therapy Near Term Product Pipeline 333.1 Leber Congenital Amaurosis 333.1.1 Unmet Need 333.1.2 Molecular Genetics 333.1.3 Luxturna (Voretigene neparvovec) 333.1.4 Editas Medicine: EDIT-101 353.1.5 Trial Design 363.1.6 EDIT-101 and Off-Target Effects 373.1.7 The Potential Advantage of EDIT-101 is the Longevity of its Therapeutic Effect 373.1.8 Summary LCA 383.2 Choroideremia 383.3 Hurler Syndrome (MPS I) 393.3.1 Key Clinical Studies 403.3.2 Regenex: RGX-111 403.3.3 Sangamo Therapeutics: SB-318 403.4 Hunter Syndrome (MPS II) 413.4.1 Unmet Need 413.4.2 Sangamo Therapeutics: SB-913 413.4.3 Immusoft Corporation: Cell Therapy 433.5 Sanfilippo Syndrome (MPS III) 433.5.1 Lysogene: LYS-SAF302 433.6 Summary MPS Disorders 443.7 Hemophilia 443.7.1 Hemophilia A 463.7.2 Summary Hemophilia A 503.7.3 Hemophilia B 513.7.4 Summary Hemophilia B 533.8 Hemoglobinopathies 543.8.1 Beta Thalassemia: Unmet Need 543.8.2 Beta Thalassemia: Molecular Genetics 553.8.3 Sickle Cell Disease: Unmet Need 563.8.4 Sickle Cell Disease: Molecular Genetics 563.9 Cellular Therapies for Hemoglobinopathies 573.9.1 Blue Bird Bio: BB-305 (LentiGlobin) 573.9.2 Sangamo: ST-400 603.9.3 CRISPR Therapeutics: CTX-001 613.9.4 Summary: Cellular Therapies for Hemoglobinopathies 623.10 Duchenne Muscular Dystrophy 633.10.1 Unmet Need 633.10.2 Molecular Genetics 633.10.3 ExonDys 51 Sarepta Therapeutics 643.10.4 Solid BioSciences: SGT-001 663.10.5 Exonics Therapeutics: CRISPR Approach 673.10.6 Summary Duchenne Muscular Dystrophy 684 Competitive Landscape 694.1 Regulatory Considerations for Developing Gene Therapy Products 694.1.1 Product Characteristics 694.1.2 Clinical Study Design for Gene Therapy Products 694.1.3 Disease specific guidance 704.1.4 Reimbursement and Payment 714.1.5 Summary Regulatory Considerations 724.2 Intellectual Property CRISPR/Cas 724.2.1 Licensing, Exploitation, and MPEG Pool 744.3 Company Analysis: Gene Editing Companies 754.3.1 Sangamo Therapeutics 754.3.2 CRISPR Therapeutics 794.3.3 Casebia Therapeutics 814.3.4 Editas Medicine 824.3.5 Intellia Therapeutics 844.3.6 Homology Medicines 864.4 Company Analysis: Pharma 874.4.1 Amgen 874.4.2 Gilead Sciences 874.4.3 Novartis 874.4.4 Sanofi 884.4.5 GlaxoSmithKline 884.4.6 Pfizer 885 Appendix 895.1 References 895.2 Report Methodology 98

and more

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Emerging Gene Therapies Market Report- Technological, Clinical, Regulatory and Competitive Landscape | Amgen, Gilead Sciences - The Daily Chronicle

With an ever-growing CRISPR genome-editing toolbox, scientists are creating crops that can resist diseases and pests, withstand global warming, and offer better nutrition. The emergence of this technology offers a crucial opportunity for renewed public engagement around crop engineering. In order to actualize the potential of CRISPR-edited food, we must work together to create and share strategies for productive dialogue. This article identifies one area of necessary improvement in communication and public engagement.

Describing how CRISPR-edited crops are arguably more natural than GMOs, or how these crops could potentially use fewer chemicals than their GMO predecessors reinforces pervasive societal suspicions of GMOs. If we think that engineered crops will play a key role in addressing environmental and public health issues, then promoting CRISPR-edited crops at the expense of GMOs is short-sighted. Instead, we must use CRISPR as a new avenue for renewing productive discourse with the public. CRISPR offers a way to bring everyone back to the table, reintroducing voices into vital conversations that will impact us all.

The question, Is this safe? captures this tension between distancing CRISPR from GMOs in order to separate a new technology from its polarized relative, while not discarding GMOs and avoiding difficult conversations. Science communicators can use the question Is this safe? as a case study to further identify problematic practices and offer strategies for communication alternatives. Before answering this question, we must better understand the consumers decision-making process.

The processes behind engineering a CRISPR-edited crop and a GMO share many commonalities and, in some instances, lead to nearly identical outcomes .

In the wake of an incoming wave of CRISPR-edited crops, communicators have an opportunity to renew conversations surrounding what is natural, and in doing so, address concerns about naturalness and safety. For science communicators, do we suggest that CRISPR-edited crops are more natural? Do we explain how brands with a natural label dont always align with what consumers think they are buying? Or do we do we zoom out and try to separate natural from safe, so we dont tacitly buy into notions that GMOs are all unsafe?

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Promoting CRISPR crops at the expense of GMOs is short-sighted when we need both - Genetic Literacy Project

Myotonic dystrophy type I (DM1) is the most common type of adult-onset muscular dystrophy. DM1 is caused by mutations in the DMPK gene. A normal DMPK gene has 3 to 37 repetitions of the CTG sequence, while in DM1, there are hundreds to thousands of repetitions of this sequence. When a DMPK gene with too many CTG repeats is transcribed, the resulting RNA is too long. This abnormally long RNA is toxic to cells, and those affected experience progressive muscle wasting and weakness.

CRISPR-Cas9 is a technique increasingly used in efforts to correct the genetic defects that cause a variety of diseases. Now a research team from the University of California, San Diego (UCSD), School of Medicine, reports they redirected the technique to modify RNA in a method they call RNA-targeting Cas9 (RCas9), to eliminate the toxic RNA and almost fully reverse symptoms in a mouse model of myotonic dystrophy.

Their findings, The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1, was published in Nature Biomedical Engineering and led by Gene Yeo, PhD, professor of cellular and molecular medicine at UCSD School of Medicine.

Myotonic dystrophy is part of a group of inherited disorders called muscular dystrophies. There are two major types of myotonic dystrophy: type 1 and type 2. The muscle weakness associated with type 1 particularly affects muscles farthest from the center of the body, such as those of the lower legs, hands, neck, and face. Muscle weakness in type 2 primarily involves muscles close to the center of the body, such as those of the neck, shoulders, elbows, and hips. The two types of myotonic dystrophy are caused by mutations in different genes.

Many other severe neuromuscular diseases, such as Huntingtons and ALS, are also caused by similar RNA buildup, explained Yeo. There are no cures for these diseases. Yeo led the study with collaborators at Locanabio and the University of Florida.

CRISPR-Cas9 works by directing Cas9 to cut a specific target gene, allowing researchers to inactivate or replace the gene. However, the Cas9 in the RCas9 method is guided to an RNA molecule instead of DNA. In a previous study, Yeo and his team established RCas9 as a means to track RNA in living cells in a programmable manner without genetically encoded tags. In a 2017 study, in lab models and patient-derived cells, the researchers used RCas9 to eliminate 95% of the abnormal RNA linked to myotonic dystrophy type 1 and type 2, one type of ALS and Huntingtons disease.

In the current study, the method goes further, by reversing myotonic dystrophy type 1 in a mouse model of the disease. Toxic RNAs expressed from such repetitive sequences can be eliminated using CRISPR-mediated RNA targeting, yet evidence of its in vivo efficacy and durability is lacking, noted the researchers. Here, using adult and neonatal mouse models of DM1, we show that intramuscular or systemic injections of adeno-associated virus (AAV) vectors encoding nuclease-dead Cas9 and a single-guide RNA targeting CUG repeats results in the expression of the RNA-targeting Cas9 for up to three months, redistribution of the RNA-splicing protein muscleblind-like splicing regulator 1, elimination of foci of toxic RNA, reversal of splicing biomarkers and amelioration of myotonia.

The researchers packaged RCas9 in a non-infectious virus. They then gave the mice a single dose of the therapy or a placebo. RCas9 reduced the abnormal RNA repeats by more than 50%, varying a bit depending on the tissue, and the treated myotonic dystrophy mice became indistinguishable from healthy mice.

To prevent the potential of the RCas9 proteins, developing an immune reaction in the mice, the researchers tried suppressing the mices immune systems briefly during treatment. As a result, they were surprised to see that they successfully prevented immune reaction and clearance. The researchers did not see signs of muscle damage, but found an increase in the activity of genes involved in new muscle formation.

Yeo believes the findings will open a new avenue of understanding and lead the way for treating other genetic diseases. This opens up the floodgates to start testing RNA-targeting CRISPR-Cas9 as a potential approach to treat other human genetic diseasesthere are at least 20 caused by buildup of repetitive RNAs, Yeo added.

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Muscular Dystrophy Condition in Mice Reversed by RNA-Targeting Cas9 - Genetic Engineering & Biotechnology News

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Sherlock Biosciences, an Engineering Biology company dedicated to making diagnostic testing better, faster and more affordable, today announced the formation of The 221b Foundation, a nonprofit organization committed to addressing the global COVID-19 pandemic by enabling access to intellectual property associated with the companys SHERLOCK CRISPR-based technology. Proceeds from any company or third-party sales of SHERLOCK CRISPR COVID-19 products will support racial and gender diversity in science, technology, engineering, and mathdisciplines collectively known as STEM.

The 221b Foundations initial leadership includes board members Rahul Dhanda, co-founder, president and CEO of Sherlock Biosciences, and Mark Jefferson, assistant dean for community engagement and equity at Harvard Law School.

COVID-19 has undoubtably had a devastating impact on the world. At the same time, there are organizations such as Sherlock that have benefitted by rapidly responding to address the pandemic, which has accelerated our companys innovation and overall plans, said Dhanda. The 221b Foundation is our way of giving back, furthering our commitment to racial and gender diversity especially within the Black Community in STEM, while also sharing our progress with other organizations that can join in the fight against this global pandemic.

The Foundations first partner in this effort is Scratch, the programming language and online community designed for young people ages 8-16. Used in more than 150 countries and available in more than 40 languages, Scratch is committed to helping young people think creatively, reason systematically and work collaboratively. Scratch, which was originally developed at MIT, will dedicate this funding to programs that benefit the Black, Latinx and Native American communities, along with young women and girls.

We are excited to partner with The 221b Foundation to advance our efforts to further equity in computer science education, particularly supporting young people from communities that face systemic inequities and injustice, said Champika Fernando, acting executive director of Scratch. Our commitment to equity and justice throughout all of our work, from the design of our creative coding tools and online community to our outreach programs that support schools and educators, aligns perfectly with The 221b Foundations mission. We look forward to working together to further our shared goal of ensuring representation and equity in STEM throughout the world.

COVID-19 and diversity issues are major crises of our time, both of which are ravaging institutions throughout the world, said Jefferson. I am excited to help The 221b Foundation lead a proactive effort to alleviate the social and healthcare burden through scientific development, educational support and community outreach.

About SHERLOCK

SHERLOCK is a method for single molecule detection of nucleic acid targets and stands for Specific High Sensitivity Enzymatic Reporter unLOCKing. SHERLOCK utilizes CRISPR as a method for smart amplicon detection and can be adapted for use with existing diagnostic instruments, improving time to result due to the technologys large multiplex capacity. When a specific sequence of DNA or RNA is present, the CRISPR enzyme is activated and, much like a pair of scissors, starts cutting nearby genetic material, releasing a fluorescent signal that indicates a positive result.

About The 221b Foundation

The 221b Foundation was founded with the dual mission to assist in the eradication of COVID-19, while supporting racial and gender diversity in STEM. By providing support and intellectual property that enables both non-profit and for-profit entities to develop CRISPR-based diagnostic testing, The 221b Foundation seeks to aid in the fight against the global COVID-19 pandemic while furthering access and diversity in STEM industries. Led by industry experts in the fields of diagnostic testing, STEM and diversity, The 221b Foundation envisions a world where advances in CRISPR technology fuel the innovations that will put an end to the COVID-19 pandemic. For more information, please visit: 221bfoundation.org.

About Sherlock Biosciences

Sherlock Biosciences is dedicated to making molecular diagnostics better, faster and more affordable through Engineering Biology platforms. The company is developing applications of SHERLOCK, a CRISPR-based method to detect and quantify specific genetic sequences, and INSPECTRTM, a Synthetic Biology-based molecular diagnostics platform that is instrument-free. SHERLOCK and INSPECTR can be used in virtually any setting without complex instrumentation, opening up a wide range of potential applications in areas including precision oncology, infection identification, food safety, at-home tests, and disease detection in the field. In May 2020, the company received Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA) for its Sherlock CRISPR SARS-CoV-2 kit, the first FDA-authorized use of CRISPR technology. For more information visit Sherlock.bio.

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Sherlock Biosciences Launches The 221b Foundation to Address the COVID-19 Pandemic and Equity in STEM - Business Wire