Archive for the ‘Gene Therapy Research’ Category

Advanced Genetics | Minecraft | 1.6.4 | A Quick Guide to Start
Get it Here: http://www.minecraftforum.net/topic/1988826-172164-forge-advanced-genetics-mod/ Attack Of The B-Team - http://www.technicpack.net/attack-of-the-...

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Genetics - Why Most Of What I #39;m Going To Tell You Is Wrong: Dr. Thomas Merritt at TEDxLaurentianU
Dr. Thomas Merritt explores the relationship between our place in time and the scientific knowledge scientists have generated and acquired up until that part...

By: TEDx Talks

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Genetics - Why Most Of What I'm Going To Tell You Is Wrong: Dr. Thomas Merritt at TEDxLaurentianU - Video

Amsterdam Weed Review - ORANGENESIA (Amnesia Haze X Agent Orange) - Lady Sativa Genetics 2014
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Amsterdam Weed Review - ORANGENESIA (Amnesia Haze X Agent Orange) - Lady Sativa Genetics 2014 - Video

The Professor D Burger Show - Genetics
DNA and Genetics Biology Project 2014. Edited by: Rahul Chaliparambil Scripted by: Preston Henning Directed by: Donavan See.

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The Professor D Burger Show - Genetics - Video

Top Scientists and Mothers Appeal to Congress for Breakthrough Therapy
Note: This video was originally posted here: http://youtu.be/DTZizFZOtQY Health staffers from over 80 Congressional offices together with agency and industry...

By: The Race to Yes

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Top Scientists and Mothers Appeal to Congress for Breakthrough Therapy - Video

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A decade and a half after a series of tragic setbacks led to critical reevaluations, scientists say gene therapy is ready to enter the clinic

Gene therapy may finally be living up to its early promise. In the past six years the experimental procedure for placing healthy genes wherever they are needed in the body has restored sight in about 40 people with a hereditary form of blindness. Doctors have seen unprecedented results among another 120-plus patients with various cancers of the bloodseveral of whom remain free of malignancy three years after treatment. Researchers have also used gene therapy to enable a few men with hemophilia, a sometimes fatal bleeding disorder, to go longer without dangerous incidents or the need for high doses of clotting drugs.

The positive results are even more impressive considering that the field of gene therapy essentially ground to a halt 15 years ago, following the untimely death of Jesse Gelsinger, a teenager with a rare digestive disorder. Gelsinger's immune system reacted to the gene treatment he received by launching a counterattack of unexpected ferocity that killed him. Gene therapy's preliminary successes in the 1990s, it turns out, had fueled unreasonably high expectations among doctors and researchersand perhaps a bit of hubris.

2014 Scientific American, a Division of Nature America, Inc.

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Gene Therapy's Second Act

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Techniques for getting past the immune system are key to safe and effective treatment

Advances in gene therapy over the past 15 years are finally allowing investigators to safely treat a growing number of carefully selected patients with a broad range of defective or missing genes, as reported by Ricki Lewis in the March issue of Scientific American. One of the biggest obstacles researchers have learned to overcome is the immune systems propensity to over-react when thousands of copies of the stripped-down viruses carrying normal genes are injected into the body, mistakenly treating them as foreign invaders.

Lewis describes the problem and various solutions that are being used in detail in her article. This animation, created by Cortical Studios and Cyberfish, demonstrates one technique that scientists now use to circumvent the immune system in the liver.

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How Gene Therapy Targets Liver Cells [Video]

London (PRWEB UK) 3 March 2014

Researchers at Oxford University have discovered that by replacing a missing gene into the retina, they can prevent cells from degenerating. Scientists hope that early intervention with the surgical treatment will halt progression of the devastating disorder before patients are entirely robbed of their sight. (http://bit.ly/1gOIohJ)

Superintendent Pharmacist at ChemistDirect, Omar El-Gohary, said: A lot of degenerative eye diseases result from faulty genes. Gene therapy is a new development, which uses technology to replace the defective genes with a normal working copy, with a single injection.

It is the first time gene therapy has successfully been applied to the light-sensitive photoreceptors of the retina, the digital camera at the back of the eye.

Results from the preliminary results done by Oxford University researchers has shown that from the first six patients to take part, two men with advanced stages of choroideremia, (a degenerative retinal disease which leads to loss in sight) experienced dramatic improvements to their sight.

A third of diseases which affect the eyes are genetic in origin and scientists are confident the therapy could be adapted to help patients with other illnesses.

El-Gohary added: Factors other than genetics contributing to the development of eye related diseases can be mutations, which can occur with age and trigger macular disease. The treatment is the same; to replace the faulty gene with a functioning one.

There are currently 500,000 people in Britain with age-related degenerative macular disease, with one in 20 people over 65 suffering from the disease. This pioneering technology could make an enormous difference to the lives of thousands. (http://bit.ly/1fhvH1I)

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Chemist Direct discusses Gene therapy that offers hope to thousands of people suffering from degenerative blindness

Right AC Joint SVF Injection Shoulder | Stem Cell Therapy | Stem Cell Injection
Eterna MD specializes in stem cell therapy and treatment. This particular case stem cells were injected into the right AC Joint in the shoulder through an ul...

By: Eterna MD Regenerative Medicine

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Right AC Joint SVF Injection Shoulder | Stem Cell Therapy | Stem Cell Injection - Video

The stem cell therapy delivering incredible results to severe MS sufferers
BEDRIDDEN AND WHEELCHAIR-BOUND TO WALKING - the extraordinary cutting edge treatment transforming lives. Telecast date: Wednesday 26 February 2014.

By: Channel Seven Perth

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The stem cell therapy delivering incredible results to severe MS sufferers - Video

Scientists have uncovered gene mutations that slash the risk of Type 2 diabetes regardless of age and weight, offering drugmakers a novel target to combat one of the major health threats confronting the modern world.

About 347 million people globally, including 25.8 million in the U.S., have diabetes, according to the World Health Organization. The Type 2 form, tied to excess weight and a sedentary lifestyle, is soaring as obesity rates rise. The ailment occurs when the body cant control blood-sugar levels with insulin made naturally by the pancreas.

The research, funded in part by Pfizer Inc., may give the New York-based drugmaker a wedge into a diabetes market that generated $42.4 billion in 2012. A drug mimicking the mutations would provide a unique way to hold the disease at bay, the researchers said in a report yesterday in the journal Nature Genetics. While current therapy slows the disease, patients eventually worsen and many need insulin shots.

The study provides important new insights into the pathogenesis of diabetes, potentially leading to the discovery of drug targets, which may result in a novel medicine, said Tim Rolph, Pfizers chief scientific officer of cardiovascular, metabolic and endocrine research, in a statement.

The researchers studied the genomes of older people with excess weight, prime targets for Type 2 diabetes who nonetheless had normal blood-sugar levels. They homed in on the SLC30A8 gene, known to affect diabetes risk.

Finally, they used advanced genetic sequencing to search the genomes of 150,000 people in the U.S., Iceland, Sweden and Finland and were able to identify a dozen variations that blocked the genes function.

Those who inherited just one copy of the damaged gene had a 65 percent lower risk of diabetes, the study found.

The protein that typically comes from the gene is critical in the production of insulin by the beta cells found in the pancreas. The researchers still arent sure exactly why or how the mutations provide protection.

Human genetics is not just a tool for understanding biology, said David Altshuler, deputy director and chief academic officer at the Broad Institute and a professor at Harvard Medical School. It can also powerfully inform drug discovery by addressing one of the most challenging and important questions - knowing which targets to go after.

The research was a five-year collaboration between researchers at the Broad Institute, Massachusetts General Hospital, Pfizer and Lund University Diabetes Center in Sweden. The National Institutes of Health, the Doris Duke Charitable Foundation and other organizations also helped fund the research.

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Type 2 Diabetes Gene Mutations Seen as Drugmaker Target

F215 genetic engineering pt 2 njlm
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By: Neil Moore

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F215 genetic engineering pt 2 njlm - Video

F215 Genetic Engineering pt1 njlm
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F215 Genetic Engineering pt1 njlm - Video

Rinehart Screencast Genetic Engineering
Video notes on Genetic Engineering.

By: Brad Rinehart

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Rinehart Screencast Genetic Engineering - Video

Genetic Engineering at Cedar Crest

By: Cedar Crest College

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Genetic Engineering at Cedar Crest - Video

Inheritance: How "Rare" Diseases Unlock Cures for Everyone
Order here: http://amzn.to/1dIUAOa Adapted from -- Inheritance: How Our Genes Change Our Lives--and Our Lives Change Our Genes by Sharon Moalem Text: "Today,...

By: Sharon Moalem

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Inheritance: How "Rare" Diseases Unlock Cures for Everyone - Video

Genetics of Color Adaptation - Hopi Hoekstra
Source - http://serious-science.org/videos/718 Harvard Prof. Hopi Hoekstra on beneficial mutations, wild mice as a model system, and patterns of genetic vari...

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Genetics of Color Adaptation - Hopi Hoekstra - Video

Timothytrespas:Morgellons microwaves genetics virus stress is killing me
Targeted individual timothytrespas: Morgellons microwaves genetic stress Eating my face Boy do I look like shit! and I feel like shit most of the time. I was...

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BRCA1/BRCA2 Gene Mutation: Dr. Peter Hulick (Medical Genetics)
Peter Hulick, MD, MMsc, Medical Geneticist at NorthShore, discusses the increased risk for breast and ovarian cancer in women who carry the BRCA1 and BRCA2 g...

By: NorthShore University HealthSystem

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BRCA1/BRCA2 Gene Mutation: Dr. Peter Hulick (Medical Genetics) - Video

ABT: Episode 1: Advanced Genetics!
Today I am starting a new series called the completely original ABT or Attack of the B Team!!! Today we are working on some advanced genetics mod!!! Sorry ab...

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ABT: Episode 1: Advanced Genetics! - Video

VaderVision - How basic Genetics concepts relate to Cannabis Breeding
Genetics? This is a basic look at breeding potential of cannabis. We are going to jump right in to phenotypes and genotypes. So for every characteristic that...

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VaderVision - How basic Genetics concepts relate to Cannabis Breeding - Video

F215 xenotransplantation gene therapy
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F215 xenotransplantation & gene therapy - Video

Stem Cell Therapy | Stem cells from osteoarthritis patients as good as controls?
http://wwwarthritistreatmentcenter.com Stem cells from patients with osteoarthritis are as good as normal controls Alwin Scharstuhl and colleagues, in an art...

By: Nathan Wei

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Stem Cell Therapy | Stem cells from osteoarthritis patients as good as controls? - Video

Annie - Before Stem Cell
Here are some REAL results from stem cell therapy. This is Annie before her stem cell therapy treatment.

By: Stacey Ragsdale

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Annie - Before Stem Cell - Video

GOODIE MOB - Cell Therapy (Official Music Video)
From the album "Soul Food" iTunes: http://www.smarturl.it/GoodieMob_SoulFood Connect with Goodie Mob: Website: http://www.GoodieMobMusic.com Facebook: https:...

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GOODIE MOB - Cell Therapy (Official Music Video) - Video