Archive for the ‘Gene Therapy Research’ Category

Heart Genetics
El jurado del Premio Emprendedores 2013 ha concedido un accésit al proyecto Heart Genetics.

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Heart Genetics - Video

Medical Educational Apps QVPrep Lite Learn genetics and genetic engineering video Part 2 3 4 5
QVprep Lite Genetic Engineering is FREE and has limited content. The app gives you the option to buy the paid QVprep Genetic Engineering app which has exhaus...

By: Deep Larry

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Medical Educational Apps QVPrep Lite Learn genetics and genetic engineering video Part 2 3 4 5 - Video

Minecraft FTB - Big Bee Project - Part 8 - Genetics
We are going to set up one of the biggest bee projects known to minecraft! watch and enjoy!! watch, enjoy, subscribe, like and await the rest 😉 Add me on tw...

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Minecraft FTB - Big Bee Project - Part 8 - Genetics - Video

Cancer Gene Therapy
A new and better way to treat cancer!

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Cancer Gene Therapy - Video

Genetic Engineering in Human DNA
Are there signs of genetic engineering in human DNA? Will Hart says that the more we learn about genetic engineering, the more it seems that this is the case...

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Genetic Engineering in Human DNA - Video

Words of Wisdom from Dr. Jane Goodall on Genetic Engineering supporting I-522
Jane Goodall, Ph. D., DBE Founder, the Jane Goodall Institute UN Messenger of Peace http://www.janegoodall.org ...

By: GMOLabelSpokane

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Words of Wisdom from Dr. Jane Goodall on Genetic Engineering supporting I-522 - Video

Genetics - The Battle Of Epping Forest
Genesis tribute from Buenos Aires, Argentina Three members of the first Rael met in 2011 to return to play the music of Genesis. Daniel Rawsi, Ignacio Rodríg...

By: Wong Pak Sam

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Genetics - The Battle Of Epping Forest - Video

GAY GENETICS! - Nov 4
yesterday #39;s vlog: http://bit.ly/1hgIGBP so RJ and i decided to sign up for 23andme thanks to this documentary we watched. Nick over at http://www.youtube.com...

By: shep689

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GAY GENETICS! - Nov 4 - Video

The Moral Maze: Genetics and Education (2/3)
For centuries philosophers and theologians have wrestled with the question of nature versus nurture. Increasingly and for some controversially, the science o...

By: PseudoAdministrator

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The Moral Maze: Genetics and Education (2/3) - Video

Genetic Engineering and Climate Change - SGC Search for Solutions
Tugman, L. 23 March 2012. Genetically Engineered Rice To Cut Greenhouse Gases. THV11. 30 October 2013. http://www.thv11.com/news/article/203411/288/Genetical...

By: Gunnar Staples

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Genetic Engineering and Climate Change - SGC Search for Solutions - Video

While scientific progress on molecular biology has a great potential to increase our understanding of nature and provide new medical tools, it should not be used as justification to turn the environment into a giant genetic experiment by commercial interests. The biodiversity and environmental integrity of the world's food supply is too important to our survival to be put at risk. What's wrong with genetic engineering (GE)?

Genetic engineering enables scientists to create plants, animals and micro-organisms by manipulating genes in a way that does not occur naturally.

These genetically modified organisms (GMOs) can spread through nature and interbreed with natural organisms, thereby contaminating non 'GE' environments and future generations in an unforeseeable and uncontrollable way.

Their release is 'genetic pollution' and is a major threat because GMOs cannot be recalled once released into the environment.

Because of commercial interests, the public is being denied the right to know about GE ingredients in the food chain, and therefore losing the right to avoid them despite the presence of labelling laws in certain countries.

Biological diversity must be protected and respected as the global heritage of humankind, and one of our world's fundamental keys to survival. Governments are attempting to address the threat of GE with international regulations such as the Biosafety Protocol.

April 2010: Farmers, environmentalists and consumers from all over Spain demonstrate in Madrid under the slogan "GMO-free agriculture." They demand the Government to follow the example of countries like France, Germany or Austria, and ban the cultivation of GM maize in Spain.

GMOs should not be released into the environment since there is not an adequate scientific understanding of their impact on the environment and human health.

We advocate immediate interim measures such as labelling of GE ingredients, and the segregation of genetically engineered crops and seeds from conventional ones.

We also oppose all patents on plants, animals and humans, as well as patents on their genes. Life is not an industrial commodity. When we force life forms and our world's food supply to conform to human economic models rather than their natural ones, we do so at our own peril.

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Genetic Engineering | Greenpeace International

Educational Apps QVprep Lite Learn genetics and genetic engineering app video part 1 introduction
QVprep Lite Genetic Engineering is FREE and has limited content. The app gives you the option to buy the paid QVprep Genetic Engineering app which has exhaus...

By: Deep Larry

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Educational Apps QVprep Lite Learn genetics and genetic engineering app video part 1 introduction - Video

Stanford Hospital #39;s Breast Cancer Experts on Genetics, Risk, and Screening Technologies
Stanford #39;s breast cancer experts share the latest information about: •Breast density and breast cancer risk •Screening recommendations •New breast imaging te...

By: StanfordHospital

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Stanford Hospital's Breast Cancer Experts on Genetics, Risk, and Screening Technologies - Video

Obesity, Depression, Alcoholism, is genetics an excuse?
We often look at conditions like obesity, addiction, depression as a result of genetics. But, are we actually using genetics as the scapegoat? Watch this cru...

By: David Essel

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Obesity, Depression, Alcoholism, is genetics an excuse? - Video

pL Genetics - Black Ops II Game Clip
Game Clip.

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pL Genetics - Black Ops II Game Clip - Video

ASA Student Stories - Joseph (Queen Mary University of London, Genetics)
Joseph pursued his undergraduate degree in Queen Mary University of London, UK, reading Genetics.

By: ASA Overseas Education Specialist

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ASA Student Stories - Joseph (Queen Mary University of London, Genetics) - Video

Let #39;s Play The Sims - Perfect Genetics Challenge - Episode 31
My Sims 3 Page: http://mypage.thesims3.com/mypage/Llandros2012 My Blog: http://Llandros09.blogspot.com My Facebook: https://www.facebook.com/Llandros09?ref=t...

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Let's Play The Sims - Perfect Genetics Challenge - Episode 31 - Video

Regenerative Cellular Therapys natural peptide cell therapies work to optimize cell energy and nutrition. Our custom peptide compounds target the effected area and exert a preventative and curative action within the cells.

In addition to treating symptoms, our bio-medications empower the cells tissue structure and organs, blocking the connection of the symptoms to the disease and making the body fit to withstand functional stress loads. All of this is done through correcting the biological process of the diseases source and its side effects using our innovative cellular therapies. More On How Treatments Work >

Peptides are now being tested at many highly reputable universities, such as the University of California (UCLA), University of Michigan and Yale. Their research is providing more and more breakthrough uses for peptides, including treating major diseases and improving anti-aging formulas. Results for a hair re-growth peptide, and a even a peptide compound that reduces the need for insulin in diabetics, are being studied at the University of Michigan and UCLA. - Read New Articles >

These peptide breakthroughs are quickly gaining momentum, but the beneficial uses will not be realized for some time due to the lengthy and expensive FDA approval process.

Peptide treatments for many conditions, such as diabetes, cirrhosis and cancer are currently only available outside of the U.S. Regenerative Cellular Therapy provides the closest and most luxurious clinic and lodging for providing patients with these new custom Peptide treatments.

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Cell Therapy with Peptide Treatments for Cancer, Diabetes and more!

Week 02 Cancer Genetics

By: UWS Mark Temple

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Week 02 Cancer Genetics - Video

Our Cell Therapy Center offers advanced patented methods of stem cell treatment for different diseases and conditions. The fetal stem cells we use are nonspecialized cells able to differentiate (turn) into any other cell types forming different tissues and organs. Fetal stem cells have huge potential for differentiation and proliferation and are not rejected by the recipients body more...

Stem cell therapy has proven to be effective for organs and tissues restoration, and for fight against the incurable and obstinate diseases. We treat patients with various diseases, such as diabetes mellitus, multiple sclerosis, Parkinsons disease, Duchenne muscular dystrophy, cancer, blood diseases and many others, including rare genetic and hereditary diseases. Among our patients there are also people willing to undergo anti-aging treatment. Stem cell treatment allows for achieving effects that are far beyond the capacity of any other modern method more...

For over 19 years, we have performed more than 7,500 transplantations of fetal stem cells to people from many countries, such as the USA, China, Italy, Germany, Denmark, UAE, Egypt, Russian Federation, Greece and Cyprus, etc. Our stem cell treatments helped to prolong life and improve life quality to thousands of patients including those suffering from the incurable diseases who lost any hope for recovery.

With Cell Therapy Center EmCell located in Kiev, Ukraine, we have numerous partners in various countries devoted to provide medical advice on EmCell stem cell treatment locally.

We are always open for medical, businessandscientificcooperation.

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Stem Cell Therapy & Stem Cell Treatment - Cell Therapy Center Emcell

SO PAULO & SAN CARLOS, Calif.--(BUSINESS WIRE)--Hospital Israelita Albert Einstein and Natera, a leading innovator in prenatal genetic testing, today announced a partnership to offer Panorama, Nateras non-invasive prenatal test. Panorama currently offers detection of chromosomal abnormalities, including trisomy 21 (Down syndrome), trisomy 13 (Patau Syndrome), trisomy 18 (Edwards syndrome), monosomy X (Turner syndrome), triploidy and vanishing twins, using only the mothers blood as early as nine weeks gestation.

Hospital Israelita Albert Einstein is committed to providing patients with the best medical care possible, and Panorama is not only a best-in-class non-invasive prenatal test but is also capable of detecting abnormalities beyond trisomies with high accuracy, said Rita Sanchez, M.D., director of maternal fetal medicine at Hospital Israelita Albert Einstein in So Paulo. This test enables us to provide expecting parents with reliable information about the genetics of their baby early on in pregnancy.

Added Matthew Rabinowitz, Ph.D., chief executive officer of Natera, Our partnership with a highly respected hospital such as Hospital Israelita Albert Einstein exemplifies Nateras commitment to delivering the highest quality of genetic tests in the world, based on accuracy, clinical coverage and fast turnaround time.

Panorama uses a simple blood draw from the mother, examines cfDNA found in maternal blood originating from both mother and fetus, and can be performed within the first trimester of pregnancy without any risk to the fetus. Panoramas technology analyzes, in a single reaction, 19,488 single nucleotide polymorphisms (SNPs), which are the most informative portions of an individuals DNA. It utilizes the NATUS [Next-generation Aneuploidy Testing Using SNPs] algorithm, an advanced version of Nateras proprietary informatics.

Across multiple clinical trials, Panorama has been validated globally for detection of trisomy 21, trisomy 18, trisomy 13, monosomy X, and now triploidy, with a sensitivity of greater than 99 percent for trisomy 21, trisomy 18, trisomy 13, and triploidy, 92 percent for monosomy X, and specificity greater than 99 percent for all syndromes tested. Panoramas clinical validation data has been reported in multiple peer-reviewed publications including the May 2013 article in Prenatal Diagnosis, authored by Professor Nicolaides, which was the first demonstration of Panoramas ability to detect triploidy. In October 2013 additional validation data was published in Fetal Diagnosis and Therapy, also authored by Professor Nicolaides, showing Panorama was able to differentiate with high accuracy between triploid and euploid cases in 56 blinded samples.

About Sociedade Beneficente Israelita Brasileira Albert Einstein (SBIBAE)

The SBIBAE operates in three integrated and equally important fronts: health care, social responsibility and the generation and dissemination of knowledge. The activities of health care are concentrated in the Hospital Israelita Albert Einstein and in the area of preventive and diagnostic medicine, which contribute to the sustainability of social responsibility, teaching and research. The Instituto Israelita Albert Einstein de Responsabilidade Social (IIRS) works in its own programs or in conjunction with public health system to help meet the health care needs, or technological skills of the community. The research and education activities are housed in the Instituto Israelita de Ensino e Pesquisa (IIEP) and confer innovation to other areas of SBIBAE.

About Natera

Natera is a leading genetic testing company that has developed a proprietary bioinformatics-based technology (NATUS) to deliver accurate and comprehensive high-throughput testing for reproductive indications from tiny quantities of DNA. Natera operates a CLIA-certified laboratory in San Carlos, Calif., providing a host of preconception and prenatal genetic testing services. Test offerings include pre-implantation genetic diagnosis to identify chromosomal anomalies or inherited genetic conditions in embryos generated during an IVF cycle; products-of-conception testing following miscarriage to rapidly and extensively analyze fetal chromosomes in order to understand the cause of the pregnancy loss; non-invasive prenatal testing to determine paternity; carrier screening tests to detect whether parents carry genetic variations that may result in disease in the child; and Panorama, a safe, simple test for pregnant women that identifies the most common chromosomal anomalies in a fetus as early as nine weeks. Natera's PreNATUS clinical trial for non-invasive screening of fetal chromosomal anomalies is funded by the NIH and is being conducted by the leaders in maternal-fetal medicine in the United States. The company was recently recognized for its work to advance prenatal care through its selection by the World Economic Forum as a 2014 Technology Pioneer. For more information, visit http://www.natera.com.

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Hospital Israelita Albert Einstein and Natera Partner to Offer Panorama™, Natera’s Non-Invasive Prenatal Test for ...

In the past few years, celebrities such as Christina Applegate and Angelina Jolie have brought to the surface the subject of genetic testing for breast cancer. After learning they carried the breast cancer gene, the women decided to have radical double mastectomies.

Both women have family histories of breast and ovarian cancers. Jolies mother died in 2007 from ovarian cancer. In 1978, Applegates mother was diagnosed with breast cancer. She survived and was able to help her daughter when Christina was diagnosed 30 years later.

Many women have close family members who have been diagnosed with breast or ovarian cancer, but few have the financial and community resources available that the celebrities do.

What are the options?

Various factors can direct a patients decisions to be tested. The genetic testing Jolie and Applegate had is available in Central Illinois, but to have the tests performed is not easy. Many questions will need to be answered by healthcare providers and the patient.

Why are you testing?

First, the patient will have to assess the need for the test.

What is really leading you to have testing? Daniel Groeppe, genetic counselor at the SIU School of Medicine may ask. Is there something about your family that youre concerned about or did you hear about it in the media? If it is the latter, then our conversation is mostly going to be about what are your chances you could even develop breast cancer based on a normal or a negative family history.

The first step is to develop a cancer family tree. All family members and all cancers should be recorded. The BRCA gene can be inherited through the father, warns SIU School of Medicine Director of Community Support, Cindy Davidsmeyer.

The BRCA1 and BRCA2 are the two genes related to breast cancer. People start off with a basic set of genes inherited from their parents. I like to think of them as instructions; kind of like the blue print, Groeppe said. If there are any changes in those instructions, we call it a mutation. When you have these mutations, then you have an increased risk for breast cancer and ovarian cancer.

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Do homework before seeking genetic tests

Oct. 30, 2013 In the first molecular genetic study of families with a history of both language impairment and autism, scientists may have uncovered a shared origin for the two conditions, an important step toward explaining why some cases of autism are accompanied by language difficulties and others are not. The study, a collaboration of The Research Institute at Nationwide Children's Hospital with experts at Rutgers University, indicates that a disorder called specific language impairment -- one of the most common developmental delays in children -- may be caused by the same genetic variants that lead to language difficulties in some children with autism. The findings are published Oct. 30 in the American Journal of Psychiatry.

As many as two-thirds of individuals with an Autism Spectrum Disorder (ASD) also have language impairments, which can range from mild limitations to complete non-verbal behavior. However, the remaining third may have normal or even above average language abilities. To investigate whether specific language impairment and language-impaired autism cases are caused by the same genetic variants, researchers examined the genetic code of 79 families with a history of both conditions.

Using a genome-wide scan and a series of language tests, the researchers identified two new genetic links for language impairment in these families: 15q23-26 and 16p12. Each of these new links is jointly related to language-impaired ASD and non-ASD related specific language impairment, suggesting a single cause for both issues.

"A genetic cause of language impairment may help explain why some kids with ASD have language impairments and others don't, as well as why some members of a family have language impairment only and others have ASD as well," says Christopher W. Bartlett, PhD, principal investigator in the Battelle Center for Mathematical Medicine at Nationwide Children's and lead author of the study. The research is part of a long-term collaboration between scientists at Nationwide Children's and Rutgers, initiated by a grant from the National Institute of Mental Health to Linda M. Brzustowicz, MD, professor of the Department of Genetics at Rutgers and senior investigator on the project.

Language impairment is not part of the diagnostic definition of ASD. And according to Dr. Bartlett, this study raises the question of whether language impairment is actually a dissociable trait in at least some forms of ASD.

"There is nothing about autism that dictates that language impairment has to occur," says Dr. Bartlett, who also is an assistant professor of pediatrics at The Ohio State University School of Medicine. "In this study, we demonstrated a shared mechanism between the two disorders. Language problems and ASD are complicated and have numerous genetic factors, but we think that many genetic factors related to communication could be the same for specific language impairment and language-impaired autism."

The genetic variations appear to be relevant to both disorders and may indicate a greater level of genetic predisposition for impairments in language ability among individuals with and without ASD in those families.

In an earlier study, the researchers found similarities in language deficit type and severity between language-impaired non-ASD and language-impaired ASD individuals in the same family. The behavioral genetics study, published in Biological Psychiatry, found that the same genes active in specific language impairment appear in ASD, but their effect is amplified in ASD. That finding, coupled with this new research, suggests that the two disorders may be on an etiological continuum.

"If further research confirms a genetic link between language impairment and ASD, then we may be able to find out why some family members only develop language impairment while others develop autism," says Dr. Bartlett. "But most of all, we want to know why there is such a range in communication abilities in children with autism -- why so many children have language difficulties when it's not required for the diagnosis."

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Scientist identify genetic link between language impairment, autism

PUBLIC RELEASE DATE:

31-Oct-2013

Contact: Judy Romero jromero@crg.org Cardiovascular Research Foundation

SAN FRANCISCO, CA October 31, 2013 According to a new study, genetic profiling of patients undergoing percutaneous coronary intervention (PCI) may help cardiology teams adjust treatment and improve ischemic outcomes for patients that do not properly metabolize thienopyridine blood thinning therapies such as clopidogrel.

Findings from the GIANT trial were presented today at the 25th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Sponsored by the Cardiovascular Research Foundation (CRF), TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.

The effectiveness of clopidogrel depends on activation to an active metabolite, principally via the CYP2C19 enzymatic pathway. Acute coronary syndrome patients that carry a CYP2C19 gene variant poorly metabolize the drug. These patients are known as slow responders and exhibit a higher one year risk of major ischemic events following PCI. Genetic tests can help identify a patient's CYP2C19 genotype, but it is unknown if on-line adjustment of thienopyridine therapy in the genetically slow-responder patient population may counteract this outcome.

The GIANT trial evaluated the clinical impact of CYP2C19 genetic profiling and compliance to an adjusted thienopyridine treatment. The primary endpoint was a composite of death, myocardial infarction, and stent thrombosis after one year in slow responder patients with appropriate therapy after genotyping, compared to non-slow responders.

The prospective, multicenter, single arm study enrolled 1,499 patients at the time of primary PCI (onset chest pain < 24 hours). Genetic profiling was performed within 48 hours after intervention to detect a loss of CYP2C19 gene function and identify a resistance to clopidogrel.

Strong recommendations for treatment adjustment were sent to investigators when patients were identified as slow responders.

Dual antiplatelet therapy (DAPT) was prescribed for 12 months after PCI and one year follow up was performed in 96.4 percent of patients (n=1,445) including objective assessment of compliance. A total of 22 percent of patients (n=319) had a profile associated with a CYP2C19 loss of function, known as the slow responder group. The remaining patients constituted the control group.

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Results of the GIANT trial reported at TCT 2013

Lets talk genetics

By: sambo20091

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Lets talk genetics - Video