Archive for the ‘Gene Therapy Research’ Category

Washington, January 20(ANI): In a mice study, Johns Hopkins researchers have found a link between elevated levels of a stress hormone in adolescence - a critical time for brain development - and genetic changes that, in young adulthood, cause severe mental illness in those predisposed to it.

The findings could have wide-reaching implications in both the prevention and treatment of schizophrenia, severe depression and other mental illnesses.

"We have discovered a mechanism for how environmental factors, such as stress hormones, can affect the brain's physiology and bring about mental illness," said study leader Akira Sawa, M.D., Ph.D., a professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine.

"We've shown in mice that stress in adolescence can affect the expression of a gene that codes for a key neurotransmitter related to mental function and psychiatric illness. While many genes are believed to be involved in the development of mental illness, my gut feeling is environmental factors are critically important to the process," Sawa added.

Sawa, director of the Johns Hopkins Schizophrenia Center, and his team set out to simulate social isolation associated with the difficult years of adolescents in human teens.

They found that isolating healthy mice from other mice for three weeks during the equivalent of rodent adolescence had no effect on their behavior. But, when mice known to have a genetic predisposition to characteristics of mental illness were similarly isolated, they exhibited behaviors associated with mental illness, such as hyperactivity. They also failed to swim when put in a pool, an indirect correlate of human depression.

When the isolated mice with genetic risk factors for mental illness were returned to group housing with other mice, they continued to exhibit these abnormal behaviors, a finding that suggests the effects of isolation lasted into the equivalent of adulthood.

"Genetic risk factors in these experiments were necessary, but not sufficient, to cause behaviors associated with mental illness in mice. Only the addition of the external stressor - in this case, excess cortisol related to social isolation - was enough to bring about dramatic behavior changes," Sawa said.

The investigators not only found that the "mentally ill" mice had elevated levels of cortisol, known as the stress hormone because it's secreted in higher levels during the body's fight-or-flight response. They also found that these mice had significantly lower levels of the neurotransmitter dopamine in a specific region of the brain involved in higher brain function, such as emotional control and cognition.

Changes in dopamine in the brains of patients with schizophrenia, depression and mood disorders have been suggested in clinical studies, but the mechanism for the clinical impact remains elusive.

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Adolescent stress linked to severe adult mental illness

Anatomy and physiology study guides
dld.bz Anatomy and physiology study guides This heavily illustrated self-teaching course gives you everything you need to - Find out how human muscles, nerves, bones,organs, glands, connective tissueand more, function and communicate with each other Discover the molecular-level workings of your glandular, genitourinary, digestive, cardiovascular, and other systems Conquer comparative and cellular physiology Get complete answer explanations for all problems Modules are clearly presented, easy to follow and thorough in content You will learn with Anatomy and physiology study guides Ex. Introduction to Basic Human Physiology Physiology of Cells and Miscellaneous Tissues Envelopes of the Body The Skeletal System Physiology and Actions of Muscles The Human Digestive System The Human Respiratory System and Breathing The Human Urinary System The Human Reproductive (Genital) System Lesson 10: Cardiovascular and Other Circulatory Systems of the Human Body The Human Endocrine System The Human Nervous System The Special Senses Some Elementary Human Genetics Ear-Eyes-Nose Injuries Musculoskeletal System Nursing Care Related to the Musculoskeletal System Anatomy and Physiology Related to Clinical Pathology Anatomy and physiology study guides

By: Hasantha Fonseka

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Anatomy and physiology study guides - Video

3.4 Codominance and Multiple Alleles Screencast
This screencast is part of LO 3.4 for the Genetics Unit.

By: J Agostino

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3.4 Codominance and Multiple Alleles Screencast - Video

Melungeon DNA: Melungeon DNA explored
Melungeon pictures photos images. Melungeon DNA: Melungeon DNA explained Melungeon truths series that tells the truth about the melungeon, alot of misinformation has been told about the melungeon, this video is part of a series that exposes the truth about the genetics of the melungeon, The Melungeon are from newman #39;s ridge in tennesse, the source melungeon are vardy collins and shepard gibson, other melungeon are the denham and mullins and goins, melungeon history is a good site to find truthful information on the melungeon people. Joanne has spent many years documenting melungeon people. according to wikipedia, Melungeon is a term traditionally applied to one of a number of "tri-racial isolate" groups of the Southeastern United States, Melungeon were often referred to as of Portuguese or Native American origin.The melungeon dna series exposes the misinformation on the melungeon people and proves the melungeon ancestors was who they said they was. Thru DNA is was showed the melungeon people have portuguesse ancestry. Many people says dna does not lie and that is exactly what was proven thru DNA tests on the melungeon people. It has been a long time since media has heard the acutal newmans ridge melungeons voice themself, now is the time the melungeon people of the ridge tell the truth about their dna results and what those dna results actually mean. In this Melungeon DNA Series, we break down different aspects of the Melungeon people to separate non melungeon from actual ...

By: Johnny Melungeon

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"Genetics" | OCE
Another oce guys 🙂

By: endureGB

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"Genetics" | OCE - Video

Genetics At Make It Magic

By: MakeItMagicShop

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Genetics At Make It Magic - Video

Little Mix - DNA HD (lyrics + download)
little mix dna lyrics video, from their album "DNA". download: albumjams.com tell me if the link doesn #39;t work, i #39;ll put another one. lyrics: Does he tell you he loves you When you least expect it Does he flutter your heart When he kisses your neck No scientist or biology It #39;s obvious, when he #39;s holding me It #39;s only natural That I #39;m so affected, ooh And my heart won #39;t beat again If I can #39;t feel him in my veins No need to question I already know It #39;s in his DNA, DD-DNA It #39;s in his DNA And he just takes my breath away Bb-breath away, I feel it every day And that #39;s what makes a man Not hard to understand, perfect in every way I see it in his face, nothing more to say It #39;s in his DD-DNA It #39;s the blue in his eyes That helps me see the future Fingerprints that leave me covered for days Yeah, hey, yeah Now I don #39;t have any first degree But I know what he does to me No need to work it out It #39;s so familiar, ohh And my heart won #39;t beat again If I can #39;t feel him in my veins No need to question I already know It #39;s in his DNA, DD-DNA It #39;s in his DNA And he just takes my breath away Bb-breath away, I feel it every day And that #39;s what makes a man Not hard to understand, perfect in every way I see it in his face, nothing more to say It #39;s in his DD-DNA It #39;s all about his kiss Contaminates my lips Our energy connects It #39;s simple genetics I #39;m the X to his Y It #39;s the color of his eyes He can do no wrong No, he don #39;t need to try Made from the best He passes all the tests Got my heart beating ...

By: LitttleMix

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Little Mix - DNA HD (lyrics + download) - Video

Amgen Inc : New Taipei Apple Daily Fraud Alert: Taiwan High Prosecutors Office, Tainan Branch
ctitv-industrial-bank-of-taiwan.tumblr.com I #39;ve been doing this a long time, and I #39;ve come to learn that predictions don #39;t mean much. Too much lies outside the realm of medical knowledge. A lot of what happens next comes down to you and your specific genetics, your attitude. No, there #39;s nothing we can do to stop the inevitable, but that #39;s not the point. The point is that you should try to make the most of the time you have left. EVER DEPENDUP CO., LTD.: iPhone : +886-4-25600139 iPad : (09) 28178387 5F.-1, NO. 415, DEHUA ST., NORTH DISTRICT, TAICHUNG CITY 404, TAIWAN (ROC) #38263; #20449; #26119; #23526; #26989; #26377; #38480; #20844; #21496; #35613; #35613;- #38515; #30408; #21513;

By: Chartis Washington

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Amgen Inc : New Taipei Apple Daily Fraud Alert: Taiwan High Prosecutors Office, Tainan Branch - Video

Little Mix - DNA (Lyrics in Description)
Credit to Little Mix! Lyrics: Does he tell you he loves you When you least expect it Does he flutter your heart When he kisses your neck No scientist, or biology It #39;s obvious, when he #39;s holding me It #39;s only natural that I #39;m so affected Oh, and my heart won #39;t beat again If I can #39;t feel him in my veins No need to question I already know It #39;s in his DNA DDD-DNA It #39;s in his DNA And he just takes my breath away BBB-Breath away, I feel it everyday And that #39;s what makes a man Not hard to understand Perfect in everyway, I see it in his face Nothing more to say, it #39;s in his DDDD-DNA It #39;s the blue in his eyes That helps me see the future Fingerprints that leave me covered For days, yeah hey yeah Now I don #39;t have, any first degree But I know, what he does to me No need to work it out it #39;s so familiar Oh whoa whoa oh And my heart won #39;t beat again If I can #39;t feel him in my veins No need to question, I already know It #39;s in his DNA DDD-DNA It #39;s in his DNA And he just takes my breath away BBB-Breath away, I feel it everyday And that #39;s what makes a man Not hard to understand Perfect in everyway, I see it in his face Nothing more to say, it #39;s in his DDDD-DNA It #39;s all about his kiss Contaminates my lips Our energy connects It #39;s simple genetics I #39;m the X to his Y It #39;s the color of his eyes He can do no wrong No he don #39;t need to try Made from the best He passes all the tests Got my heart beating fast It #39;s cardiac arrest He #39;s from a different strain That science can #39;t explain I guess that #39;s ...

By: Priscila Sanchez

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Little Mix - DNA (Lyrics in Description) - Video

Rudy Tanzi: Super Brain
http://www.cyacyl.com http://www.joanherrmann.com Your brain is capable of incredible healing and constant reshaping and through a new relationship with your brain you can transform your life. Rudolph E. Tanzi, PhD, a Harvard Medical School professor and one of the foremost experts on the brain, has teamed up with best selling author and physician, Deepak Chopra, for his new book, Super Brain: Unleashing the Explosive Power of Your Mind to Maximize Health, Happiness, and Spiritual Well-Being. These pioneers in health combine cutting-edge research and age-old spiritual wisdom to demonstrate that through increased self-awareness and conscious intention, you can train your brain to reach far beyond its present limitations. Dr. Tanzi guests on CYAYCL to discuss how to use your brain instead of letting it use you; create the ideal lifestyle for a healthy brain; reduce the risks of aging; promote happiness and well-being through the mind-body connection; access the enlightened brain, the gateway to freedom and bliss; and overcome the most common challenges like memory loss, depression, anxiety, and obesity. Dr. Tanzi is the Joseph P. and Rose F. Kennedy professor of Neurology at Harvard University, and director of the Genetics and Aging Research Unit at Massachusetts General Hospital (MGH). Dr. Tanzi co-discovered the first Alzheimer #39;s disease gene and several others, as head of the Alzheimer #39;s Genome Project and is the co-author of the book Decoding Darkness: The Search for the Genetic ...

By: cyacyl

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Rudy Tanzi: Super Brain - Video

Genetics Vs Conditioning
When it comes to weight loss many blame genetics. Today John discusses Genetics Vs Conditioning.

By: John Rowley

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Genetics Vs Conditioning - Video

Twin DNA Test
DNA testing is the most accurate method to determine if twins are identical or fraternal. Since 1994, Affiliated Genetics has performed more twin zygosity tests for physicians, researchers and the public than any other laboratory. We are one of less than 50 laboratories in the world accredited to perform relationship testing.

By: AffiliatedGenetics

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Twin DNA Test - Video

UNIT #2- video 6-Madera-Abuses-Dogs.m4v
News clip that demonstrates a truly abused (documented police case) puppy who is playful and has a happy temperament. By looking at this dog you #39;d never know he was abused. This video is used to demonstrate the human behavior where people misinterpret FEARFUL behavior in dogs and assume they are "abused." When a dog cowers in fear, it can be that the dog was NEVER abused at all, but that it simply has a skittish, fearful temperament due to genetics and puppyhood experiences. If you find a fearful dog, DO NOT ASSUME IT WAS ABUSED!! http://www.missingpetpartnership.org

By: pethunters

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UNIT #2- video 6-Madera-Abuses-Dogs.m4v - Video

UNIT #2 -Video 7-Abused-Pitbull.m4v
News story of physically abused pit bull. This video demonstrates that a bonafide abused dog might not LOOK abused--this dog is wiggly, friendly, happy and if not for the burn marks you #39;d not know this dog truly was abused. People who find skittish, fearful dogs often assume they are "abused" when in fact they are simply skittish, fearful dogs simply because they were born that way. Fearful behavior can be to genetics and puppyhood behavior, not necessarily because they were treated wrong.

By: pethunters

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UNIT #2 -Video 7-Abused-Pitbull.m4v - Video

Dr Naresh Trehan explains the role of genetics in the possibility of a heart disease
Dr Naresh Trehan, leading Cardio Vascular Cardio Thoracic surgeon and the chairman of Medanta hospital explains if genetics and family history play a role in the possibility of a person getting heart disease.

By: wonderdoctorindia

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Dr Naresh Trehan explains the role of genetics in the possibility of a heart disease - Video

SEATTLE, WA--(Marketwire - Jan 18, 2013) - Atossa Genetics, Inc. ( NASDAQ : ATOS ) announced today that Kyle Guse, chief financial officer, general counsel and secretary, will present at the NINE 2013 - Noble Financial Capital Markets' Ninth Annual Equity Conference held at the Hard Rock Hotel & Casino, Hollywood, Florida, on Tuesday, January 22, at 3:00 pm Eastern Time. A webcast of the presentation will be available on Atossa's web site at http://www.atossagenetics.com.

Mr. Guse stated, "I look forward to participating in this prestigious conference and presenting the Atossa Genetics story to investors. My presentation will include a discussion of the recently announced national rollout of our ForeCYTE Breast Health Test, further commercialization of our ArgusCYTE Breast Health Test, advancement of two additional tests and of the planned clinical development of our intraductal therapeutic for treatment of pre-cancerous cellular changes as a means to potentially prevent breast cancer."

About Atossa Genetics, Inc.

Atossa Genetics, Inc. ( NASDAQ : ATOS ), The Breast Health Company, is based in Seattle, Washington, and is focused on preventing breast cancer through the commercialization of patented, FDA-cleared diagnostic medical devices and patented, laboratory developed tests (LDT) that can detect precursors to breast cancer up to eight years before mammography, and through research and development that will permit it to commercialize treatments for pre-cancerous lesions.

The National Reference Laboratory for Breast Health (NRLBH), a wholly owned subsidiary of Atossa Genetics, Inc., is a CLIA-certified high-complexity molecular diagnostic laboratory located in Seattle, WA, that provides the patented ForeCYTE Breast Health Test, a risk assessment test for women 18 to 73 years of age akin to the Pap smear, and the ArgusCYTE Breast Health Test, a blood test for recurrence in breast cancer survivors that provides a "liquid biopsy" for circulating cancer cells and a tailored treatment plan for patients and their caregivers.

Forward-Looking Statements

Except for the historical information contained herein, the matters set forth in this press release, including statements regarding Atossa's plans, expectations, projections, potential opportunities, goals and objectives are forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from the anticipated or estimated future results, including the risks and uncertainties associated with the efficacy of Atossa's products and services, the market demand for and acceptance of Atossa's products and services and other risks detailed from time to time in the Atossa's final prospectus, dated November 7, 2012, filed with the U.S. Securities and Exchange Commission and other filings with the SEC.All forward-looking statements are qualified in their entirety by this cautionary statement, and Atossa undertakes no obligation to revise or update any forward-looking statement to reflect events or circumstances after the issuance of this press release.

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Atossa Genetics, Inc. to Present at NINE 2013 - Noble Financial Capital Markets' Ninth Annual Equity Conference

One of the defining features of humans is that the shape of our hands and fingers allows us to touch the tips of our fingers with our thumbs. As a result, we are able to pick up and manipulate very small objects – something other primates can’t do. Textbooks describe this human anatomical feature as having “opposable thumbs”. Allegedly it is a feature that has given us an evolutionary advantage.

Now researchers report that there’s another unique feature of the human hand that also confers an evolutionary advantage. According to a recent paper published in the Journal of Experimental Biology, the structural arrangement of the bones in the hand and the wrist allow us to make a very effective fist, for use as a weapon. The report demonstrates rather convincingly that when we curl the four fingers into the palm and then position the thumb over the index and second finger, the unique shape of the human fist allows the palm to buttress and support the fingers when we strike a blow. As a result, more force is transmitted by the knuckles than would be possible with the hand anatomy of other primates.

The authors of the study suggest that being able to use the fist as a weapon confers an evolutionary advantage. In other words, our hand evolved not only to be able to manipulate small objects easily, but also to fight effectively.Source:
http://humanbiologyblog.blogspot.com/2013/01/the-human-hand-makes-good-fist.html

Until the very end of 2012, industry experts were predicting that the construction of new wind turbines for generating electricity would decline by as much as 90 percent in 2013. That was because a tax credit amounting to about $1 million dollars per windmill was set to expire on Dec. 31, 2012. Wind turbine developers rushed a lot of new wind turbines into production in 2012 in order to take advantage of the credit, but had essentially no plans for new construction in 2013. Had the tax credit actually expired, more than 30,000 jobs might have been lost in the industry.

But the industry got a last-minute reprieve as part of the fiscal cliff negotiations in the final days of 2012. Part of the tax package included in the final fiscal cliff deal was an extension of the tax credit for wind turbine construction that begins in 2013, provided that construction is completed by 2014. That gives the industry some breathing room, at least for now.

Federal tax credits are sometimes used to encourage the development of new industries that may not yet be cost-effective. The wind turbine industry has been granted tax credits three times since 1990. This time around, concerns over the national debt mean that there is likely to be very little enthusiasm in Congress for extending the subsidy (amounting to over a billion dollars a year) yet again after this one expires.

Currently, wind energy accounts for 23 percent of all electricity generated from renewable resources, according to government statistics. The other renewable energy sources are hydropower (63%), wood and biomass waste (11%), geothermal (3%), and solar.Source:
http://humanbiologyblog.blogspot.com/2013/01/wind-turbine-tax-credit-is-renewed.html

Is it okay for pregnant women to get a flu shot? The answer is “yes”, according to a study conducted in Norway recently. (The research was conducted in Norway because access to health care in Norway is nearly universal, and good records are kept.) The results of the study are published in the New England Journal of Medicine. 

 The researchers reviewed the outcomes of the pregnancies of over 100,000 women in Norway during 2009 and 2010, about half of whom received the flu vaccine during the second or third trimester (the other half served as the control group). As expected, vaccination during pregnancy reduced the risk of getting the flu by about 70% compared to the control group. Vaccination during pregnancy also appeared to reduce the risk of fetal death slightly, but the reduction was not statistically significant.

Pregnant women tend to suffer more complications of the flu than non-pregnant women, in part because their immune systems are partially suppressed during pregnancy. So it’s important that they understand that they can get a flu shot without harming their babies. In fact, the flu vaccine may be good for the fetus/newborn as well as good for the mother; antibodies produced by the mother can cross the placenta (protecting the fetus) and are found in the mother’s milk (protecting the newborn for up to six months).Source:
http://humanbiologyblog.blogspot.com/2013/01/pregnancy-and-flu-vaccine.html

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/7pv874/drug_delivery_in) has announced the addition of Jain PharmaBiotech's new report "Drug Delivery in Cancer - Technologies, Markets and Companies" to their offering.

Drug delivery remains a challenge in management of cancer. Approximately 12.5 million new cases of cancer are being diagnosed worldwide each year and considerable research is in progress for drug discovery for cancer. Cancer drug delivery is no longer simply wrapping up cancer drugs in a new formulations for different routes of delivery. The focus is on targeted cancer therapy. The newer approaches to cancer treatment not only supplement the conventional chemotherapy and radiotherapy but also prevent damage to normal tissues and prevent drug resistance.

Innovative cancer therapies are based on current concepts of molecular biology of cancer. These include antiangiogenic agents, immunotherapy, bacterial agents, viral oncolysis, targeting of cyclic-dependent kinases and tyrosine kinase receptors, antisense approaches, gene therapy and combination of various methods. Important methods of immunotherapy in cancer involve use of cytokines, monoclonal antibodies, cancer vaccines and immunogene therapy.

Several innovative methods of drug delivery are used in cancer. These include use of microparticles as carriers of anticancer agents. These may be injected into the arterial circulation and guided to the tumor by magnetic field for targeted drug delivery. Polyethylene glycol (PEG) technology has been used to overcome some of the barriers to anticancer drug delivery. Encapsulating anticancer drugs in liposomes enables targeted drug delivery to tumor tissues and prevents damage to the normal surrounding tissues. Monoclonal antibodies can be used for the delivery of anticancer payloads such as radionucleotides, toxins and chemotherapeutic agents to the tumors.

Antisense oligonucleotides have been in clinical trials for cancer for some time now. RNAi has also been applied in oncology. Small interfering RNAs (siRNAs) can be targeted to tumors and one example is suppression of H-ras gene expression indicating the potential for application in therapy of ovarian cancer. Cancer gene therapy is a sophisticated form of drug delivery for cancer. Various technologies and companies developing them are described. Nucleic acid-based cancer vaccines are also described.

The market value of drug delivery technologies and the anticancer drugs are difficult to separate. Cancer market estimates from 2012-2022 are given according to organs involved and the types of cancer as well as according to technologies. Distribution of the into major regions is also described.

Profiles of 222 companies involved in developing innovative cancer therapies and methods of delivery are presented along with their 249 collaborations. The bibliography contains over 650 publications that are cited in the report.The report is supplemented with 60 tables and 9 figures.

Key Topics Covered:

1. Introduction to cancer therapy

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Research and Markets: Drug Delivery in Cancer - Technologies, Markets and Companies - 2013 Report

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/p6tm2n/rnai) has announced the addition of Jain PharmaBiotech's new report "RNAi - Technologies, Markets and Companies" to their offering.

RNA interference (RNAi) or gene silencing involves the use of double stranded RNA (dsRNA). Once inside the cell, this material is processed into short 21-23 nucleotide RNAs termed siRNAs that are used in a sequence-specific manner to recognize and destroy complementary RNA. The report compares RNAi with other antisense approaches using oligonucleotides, aptamers, ribozymes, peptide nucleic acid and locked nucleic acid.

Various RNAi technologies are described, along with design and methods of manufacture of siRNA reagents. These include chemical synthesis by in vitro transcription and use of plasmid or viral vectors. Other approaches to RNAi include DNA-directed RNAi (ddRNAi) that is used to produce dsRNA inside the cell, which is cleaved into siRNA by the action of Dicer, a specific type of RNAse III. MicroRNAs are derived by processing of short hairpins that can inhibit the mRNAs. Expressed interfering RNA (eiRNA) is used to express dsRNA intracellularly from DNA plasmids.

Delivery of therapeutics to the target tissues is an important consideration. siRNAs can be delivered to cells in culture by electroporation or by transfection using plasmid or viral vectors. In vivo delivery of siRNAs can be carried out by injection into tissues or blood vessels or use of synthetic and viral vectors.

Because of its ability to silence any gene once the sequence is known, RNAi has been adopted as the research tool to discriminate gene function. After the genome of an organism is sequenced, RNAi can be designed to target every gene in the genome and target for specific phenotypes. Several methods of gene expression analysis are available and there is still need for sensitive methods of detection of gene expression as a baseline and measurement after gene silencing. RNAi microarray has been devised and can be tailored to meet the needs for high throughput screens for identifying appropriate RNAi probes. RNAi is an important method for analyzing gene function and identifying new drug targets that uses double-stranded RNA to knock down or silence specific genes. With the advent of vector-mediated siRNA delivery methods it is now possible to make transgenic animals that can silence gene expression stably. These technologies point to the usefulness of RNAi for drug discovery.

Regulatory, safety and patent issues are discussed. Side effects can result from unintended interaction between an siRNA compound and an unrelated host gene. If RNAi compounds are designed poorly, there is an increased chance for non-specific interaction with host genes that may cause adverse effects in the host. However, there are no major safety concerns and regulations are in preliminary stages as the clinical trials are still ongoing and there are no marketed products. Many of the patents are still pending.

The markets for RNAi are difficult to define as no RNAi-based product is approved yet but several are in clinical trials. The major use of RNAi reagents is in research but it partially overlaps that of drug discovery and therapeutic development. Various markets relevant to RNAi are analyzed from 2012 to 2022. Markets are also analyzed according to technologies and use of siRNAs, miRNAs, etc.

Profiles of 161 companies involved in developing RNAi technologies are presented along with 229 collaborations. They are a mix of companies that supply reagents and technologies (nearly half of all) and companies that use the technologies for drug discovery. Out of these, 33 are developing RNAi-based therapeutics and 34 are involved in microRNAs. The bibliography contains selected 600 publications that are cited in the report. The text is supplemented with 34 tables and 11 figures.

Key Topics Covered:

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Research and Markets: RNAi - Technologies, Markets and Companies - 2013 Report

New Delhi, Jan. 18: A promise of anonymity in genomic research may be misleading.

A new study has shown that it is possible to determine the identities of people who have anonymously contributed genetic material for research, exposing gaps in existing security structures for personal genetic information.

A team of US scientists has combined genomic information with Internet search tools and public databases to identify nearly 50 individuals in America who had provided their genetic material as participants in genomic studies.

The researchers used genetic markers found on the Y-chromosome, which moves from father to son to first infer the surnames of the individuals and then used several public databases to determine their identities. The study appears today in the US journal Science.

"Our results show it is possible to identify some individuals who may have wished to remain anonymous," said Yaniv Erlich, principal investigator at the Whitehead Institute for Biomedical Research at the Massachusetts Institute of Technology and senior author of the study.

Erlich and his colleagues have not revealed the identities of these individuals but shared their methodology of breaching privacy with senior staff at the US National Institutes of Health before the publication of the research.

The researchers hope the study will stimulate debate and research on policy guidelines and security procedures to protect the privacy of genetic information that can potentially reveal health information about individuals.

"We don't want people to stop donating genetic material and we want the public sharing of data to continue," Erlich told The Telegraph. "This study was intended to help policy makers and individuals appreciate the benefits and the risks of releasing genetic data."

The Whitehead researchers used genetic markers called short-tandem ' repeats on the Y-chromosome or Y-STRs ' that can provide information on paternal lineages when combined with recreational genetic genealogy databases.

The scientists used the two largest public genetic genealogy databases 'www.ysearch.org and http://www.smgf.org ' that are free-of-charge and are equipped with search engines.

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Study exposes hole in gene security

Gene therapy PowerPoint Template - Gene therapy PowerPoint (PPT) Backgrounds Templates (Download)
Download - beefile.info/apps/download.php?dl=Gene-therapy-PowerPoint-Template---Gene-therapy-PowerPoint-(PPT)-Backgrounds-Templates

By: alan baumen

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Gene therapy PowerPoint Template - Gene therapy PowerPoint (PPT) Backgrounds Templates (Download) - Video

Local Non-Profit funds Cancer Research
Watch more and discuss: stamford.itsrelevant.com The Alliance for Cancer Gene Therapy has awarded millions to cancer research. The Stamford-based Alliance was founded by Greenwich residents Edward and Barbara Netter.

By: irstamford

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Local Non-Profit funds Cancer Research - Video

MANILA, Philippines --- The Department of Health (DOH) is preparing guidelines for the use of stem cell therapy in the treatment of diseases in the Philippines.

This was announced by DOH Secretary Enrique T. Ona yesterday in a convention on stem cell therapy at the Manila Hotel.

Ona said a bio-ethics advisory board will develop the guidelines which will include ethical standards in the application of stem cell therapy to treat diseases such as malignancies, blood disorders and metabolic disorders, among others.

"The institutional board will review and approve Stem Cell therapies based on guidelines by the advisory board," Ona said.

He added that the board will also include ethical and legal issues surrounding stem cell therapy.

Last week, the Philippine Medical Association (PMA) and the Philippine Society for Stem Cell Medicine (PSSCM) issued a joint statement that warned against the dangers of receiving stem cell transplants that came from another source other than the patient's body.

"If the stem cell that you received is not from your own body, it could lead to fatal complications," Philippine Society for Stem Cell Medicine (PSSCM) and the PMA said.

The doctors warned that complications arising from stem cell transplants include graft-versus-host disease, stem cell (graft) failure, organ injury, infections, cataracts, infertility, new cancers, and even death.

Ona said a public hearing will be held on January 18 regarding the preliminary draft of the guidelines.

He said the guidelines will ensure the minimum quality of service and application in the use of stem cells in health settings.

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Stem Cell Therapy Guidelines Readied