Archive for the ‘Gene Therapy Research’ Category

Potato Genetics
Following last year #39;s successful mapping of the potato genome, and the recent World Potato Congress in Edinburgh - Professor Robbie Waugh talks to Andrew Cassell about the huge advances made in crop research as a result of breakthroughs in genetics.From:jameshuttoninstituteViews:0 0ratingsTime:04:09More inScience Technology

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An organism as a living system
VideoLectures.Net View the talk in context: videolectures.net View the complete International Conference Bioscience and Society: Organisms as living systems: videolectures.net Speaker: Denis Noble, Department of Physiology, Anatomy Genetics, University of Oxford License: Creative Commons CC BY-NC-ND 3.0 More information at videolectures.net More talks at videolectures.net 0:00 The Music of Life - 1 6:40 The Music of Life - 2 7:26 Selfish Genes 10:16 Genes as Prisoners 13:31 Selfish or Cooperative Genes? 14:09 The Story 15:24 Picture - 1 15:31 Picture - 2 15:35 Picture - 3 15:48 Picture - 4 15:51 Picture - 5 15:55 Picture - 6 17:19 Picture - 7 20:35 Square 36 20:47 Square 50 20:53 Square 64 21:06 The genome and combinatorial explosion 24:02 The UNIVERSE 24:54 Number of galaxies 25:35 Total number of atoms 29:39 The French bistro omelette - 1 31:42 The French bistro omelette - 2From:VideoLecturesChannelViews:0 0ratingsTime:40:27More inEducation

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An organism as a living system - Video

STOCKHOLM, December 6, 2012 /PRNewswire/ --

Online audiences have an opportunity to pose questions to Nobel Laureates, other prominent scientists and thought leaders about genetics and genomics at a unique science conference, titled Nobel Week Dialogue, taking place on December 9th 2012. Focusing on the theme of "The Genetic Revolution and its Impact on Society", this one day meeting will review current and future prospects for personalised medicine, genetically modified organisms and human evolution and biology. The conference will be streamed live onnobelweekdialogue.org. Due to great interest, the conference is now fully booked.

Questions can be submitted ahead of time with and during the live streaming of the afternoon group discussion panels where topics will include: The Promised Land of Genomic Medicine: Where Can the Science Take Us and How Do We Actually Get There; Genetics in Agriculture and the Environment: Where Are We Going and How Can We Get There?;Genetics and Nurture: Understanding the Interactions Between Genetics and the Environment;Human Evolution: Where Have We Been and Where Are We Going?; and Human Biology: The Great Deal We Don't Know and How to Discover It. These questions may contribute to shaping the discussions. Questions can be submitted via Google Moderator or email: nobelweekdialogue@gmail.com For more information: http://www.nobelweekdialogue.org/programme/live-event-webcasts/

Participating Nobel Laureates include Bruce Beutler (2011), Steven Chu (1997), Joseph Goldstein (1985), Craig Mello (2006), Christiane Nsslein-Volhard (1995) James Watson (1962) and Kurt Wtrich (2002).

Additional participating experts include Mary-Claire King, President of the American Society of Human Genetics, Eric Lander, founder of the Broad Institute of Harvard and MIT, John Dupr, Director of the ESRC Centre for Genomics in Society and Janet Woodcock, Director of the Center for Drug Evaluation and Research at the Food and Drug Administration. For a complete list of participants, see: http://www.nobelweekdialogue.org/participants/

Follow Nobel Week Dialogue event blog: http://www.nobelweekdialogue.org/media/blog/

Facebook: http://www.facebook.com/NobelWeekDialogue

Or Twitter: @nobelweekdialog #nwd12

About Nobel Week Dialogue

During the annual Nobel Week, held each December in Stockholm, the current year's Nobel Laureates participate in a whirlwind of events and activities leading up to 10 December, when they receive their Nobel Prize and attend the Nobel Banquet. This year, the roster of activities has been expanded to include a new conference: Nobel Week Dialogue, taking place on December 9th.

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Submit Questions to Nobel Laureates and Other Experts about Genetics and Society

PORT ST. LUCIE, Fla.--(BUSINESS WIRE)--

The Vaccine and Gene Therapy Institute of Florida (VGTI Florida) is pleased to announce the appointment of Catherine E. Vorwald to Director, Business Development.

We dedicate ourselves every single day to finding novel treatments for chronic diseases like cancer and HIV/AIDS, said Mel Rothberg, Chief Operating Officer, VGTI Florida. Were pleased to have Catherine onboard. By leading our business development efforts, she will facilitate the commercial translation of therapeutic discoveries so that patients around the world will ultimately be better served and suffer less, he continued.

Catherine will work closely with VGTI Florida leadership to develop and implement a comprehensive strategic approach including growing the intellectual property portfolio, commercializing therapeutic discoveries, and developing an innovation center, based on the institutes technology, for new entities and emerging companies wishing to co-locate and utilize the core facilities and expertise available at the Tradition Center for Innovation.

VGTI Florida has a wealth of expertise and therapeutic discovery potential and I am dedicated to translating these capabilities to industry so that they become a standard part of medical care, said Catherine.

As an accomplished technology commercialization executive, Catherine brings extensive domestic and international biotechnology and life science management experience to VGTI Florida. She specializes in fostering relationships between the academic and corporate communities. Catherine spent nearly six years as Director of Business Development working on marketing and leasing activities for Wexford Science + Technology, LLC, a real estate developer of university technology research parks. Her career encompasses technology commercialization from a variety of aspects, namely, marketing and business development at companies ranging from Fortune 500 to start-ups, academic research at the National Institutes of Health (NIH) and the University of California, San Francisco and technology transfer at Stanford and Johns Hopkins Universities.

Catherine has served as a board member of two notable technology incubators, the Emerging Technology Center of Baltimore and the Economic Development Corporation of South Florida. She is a former board member of The Licensing Executives Society USA-Canada, Inc., and the LES Foundation. She also founded the Licensing Executives Society Maryland Local Chapter. Catherine holds a Master of Business Administration in Finance from The Johns Hopkins University as well as a Master of Science Degree from Georgetown University and a Bachelor of Arts in Biological Sciences from the University of California.

VGTI Florida

VGTI Florida is a leading immunological research institute that is on an urgent mission to transform scientific discoveries into novel treatments and cures for devastating chronic illnesses such as cancer and HIV/AIDS. VGTI Florida is an independent non-profit 501 (c) 3 organization located in the Tradition Center for Innovation in Port St. Lucie, Florida. For more information, please visit our website at http://www.VGTIfl.org.

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VGTI Florida Announces New Director of Business Development

Genetic Engineering and Biotechnology Project
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Genetic Engineering and Biotechnology Project - Video

Video295
Genetic EngineeringFrom:alejandra LiottaViews:4 0ratingsTime:05:02More inEducation

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A new test may be better at detecting potentially harmful genetic changes in children before they are born than current methods, researchers say.

The test, called a chromosomal microarray, detected more irregularities that could result in genetic diseases such as missing or repeated sections of genetic code than did karyotyping, which is the current standard method of prenatal testing.

For instance, children who are missing a small portion of chromosome 22 will be born with DiGeorge syndrome, which can cause severe heart defects and developmental delays. In the study, a chromosomal microarray detected this missing section and diagnosed the condition, whereas a karyotype is not able to find the change.

Microarrays also identified some genetic changes linked to autism not revealed by karyotyping.

The findings suggest microarray should replace karyotyping as the standard method of finding genetic irregularities in fetuses, said study researcher Dr. Ronald Wapner, an obstetrician and gynecologist at Columbia University in New York. Microarrays are already used to diagnose genetic conditions in children with developmental disabilities and birth defects.

However, experts cautioned that microarrays could provide more information than is useful. Some abnormalities identified by the test are new, and have unknown or uncertain consequences, which can put stress on families. [See 11 Big Fat Pregnancy Myths.]

It is critical that parents who receive this type of testing are counseled before and after the test about what the findings could mean, experts say.

Microarrays vs. karyotype

In karyotyping, fetal cells are analyzed under a microscope, which allows researchers to see whether too many or too few chromosomes are present, or if the chromosomes have an abnormal structure. In contrast, microarrays compare a sample of the fetus' DNA with that of a healthy person, giving researchers a closer look at the genetic code.

Both tests require amniocentesis, a procedure that takes fetal cells from the amniotic fluid and comes with risks, including a small risk of miscarriage.

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Genetic Test Could Better Reveal Fetal Abnormalities

PHOENIX, Dec. 5, 2012 /PRNewswire/ -- Phoenix Children's Hospital announced the creation of the Ronald A. Matricaria Institute of Molecular Medicine today, with the goal to unlock genetic codes and develop drug therapies in real time to improve the outcome for thousands of young patients.

To view the multimedia assets associated with this release, please click: http://www.multivu.com/mnr/59399-phoenix-children-s-hospital-visionary-institute-of-molecular-medicine

(Photo: http://photos.prnewswire.com/prnh/20121205/MM23568)

"Our goal is to bring genomics research to the forefront of pediatrics," said Robert L. Meyer, Phoenix Children's president and CEO. "Research and development of novel treatments for pediatric diseases has fallen short over past decades." According to the National Heart, Lung and Blood Institute,70 percent of all medications prescribed to children have been tested only in adults. Clinical studies in children lead to a better understanding of the specific differences between children and adults, thus leading to the development of safer, more effective, and age-appropriate treatments.

"We also must address a fundamental flaw in traditional and personalized medicine diagnosis and treatment of a disease based on clinical instead of genomic information," Meyer noted.

Molecular, or personalized, medicine uses genetic information to determine the right treatment for the right patient at the right time. By studying a patient's genetic makeup, researchers can identify the individual's susceptibility to disease, predict their response to a particular drug, and match the patient with a specific therapy. The team will focus on pediatric cancers in phase one, and expand to other pediatric diseases over time.

Two distinguished scientists are joining Phoenix Children's and were named the institute's co-directors:

A critical component to this venture is Phoenix Children's collaborative relationships with leading bioscience institutions. The University of Arizona College of Medicine Phoenix brings academic and research programs, as well as academic credentials necessary to recruit and develop a research program.

The College utilized a $1.25 million gift from the Virginia G. Piper Charitable Trust to help secure the two endowed chairs.

"The Institute is a critical piece in the development of our campus and the emerging academic medical center in Phoenix," said Stuart D. Flynn, dean of the College of Medicine Phoenix. "This program will catalyze Phoenix Children's Hospital and our region to become national contributors and leaders in molecular medicine.

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Phoenix Children's Hospital Announces Formation of Pediatric Institute of Molecular Medicine

Preview of DNA
Preview of DNA for genetics unit!From:Dana DossViews:1 0ratingsTime:04:12More inEducation

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Preview of DNA - Video

Alumni Video - Marc Hammarlund
Marc Hammarlund is an alumni of the University of Utah Molecular Biology program. He graduated with his PhD in Biology and is currently an Assistant Professor of Genetics at Yale University.From:UofUBiosciencePhDViews:2 0ratingsTime:02:43More inEducation

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Alumni Video - Marc Hammarlund - Video

Drosophila, baby! - Genetics Call Me Maybe Parody
Drosophila, BabyFrom:localsurfacousticViews:9 0ratingsTime:03:16More inFilm Animation

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Drosophila, baby! - Genetics Call Me Maybe Parody - Video

Pancreatic Cancer Awareness Day - Prevention Genetics, Dr. Fay Kastrinos (9)
Dr. Kastrinos was the ninth in a series of speakers who participated in the November 3rd Annual Pancreatic Cancer Awareness Day. Dr. Kastrinos describes the role of prevention and genetics in the detection of pancreatic cancer. For more information about the Pancreas Center visit pancreasmd.org, call 212-305-9467, or email info@columbiasurgery.org.From:ColumbiaSurgeryViews:1 0ratingsTime:06:39More inEducation

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Pancreatic Cancer Awareness Day - Prevention

Ahmanson Lectures on Creation
The Ahmanson Lectures on Creation bring facts, historical evidence, philosophical and scientific investigations to Christianity. Taught during Saddleback Church #39;s Apologetics Weekend, five professionals in the field, some atheists turned Christian, reenergize our faith as they teach the evidence of Christianity in science, nature, genetics and living cells, the origin of the universe, and more. In this first message in the Ahmanson Lectures on Creation, we hear from Lee Strobel. Former award winning legal editor for the Chicago Tribune, author of several books including The Case for Christ and The Case for a Creator, former Saddleback pastor and former atheist, Strobel teaches a message on three areas of science that give powerful evidence to God #39;s existence.From:SaddlebackResourcesViews:0 0ratingsTime:03:51More inNonprofits Activism

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Professor Robin Feldman on Myriad
The US Supreme Court has granted review in Association for Molecular Pathology v. Myriad Genetics on the specific question, "Are human genes patentable?" UC Hastings College of the Law Professor Robin Feldman discusses that question, plus the "quartet of Supreme Court patent law decisions" that she believes may soon become a "quintet." Professor Robin Feldman #39;s work is widely regarded as some of the most influential scholarship in the field of patent law. She offered significant commentary to multiple media outlets during the Apple v. Samsung patent lawsuit and its recent groundbreaking decision. Her latest book, Rethinking Patent Law, was published by Harvard University Press in 2012 and explains patent bargaining. Her bio and publications are available at tinyurl.comFrom:uchastingslawViews:1 0ratingsTime:05:49More inEducation

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Professor Robin Feldman on Myriad - Video

Bronson-"Man With a Camera" shows "Hard Times" moves
Charles Bronson forced to box for his life in the TV show, Man With a Camera. On Netflix streaming. Notice the tight, triple cross combo is the same as the one he would use years later in Hard Times. This is second season Man With A Camera. Where, like Wild Wild West , they figured out it was a good idea for Bronson to have his shirt off. The first season he had a single episode with his shirt off. It #39;s genetics. The guy Bronson is boxing probably works just as hard as Bronson staying fit.From:plazpasticViews:0 0ratingsTime:02:08More inFilm Animation

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Bronson-"Man With a Camera" shows "Hard Times" moves - Video

Monster Dab @ the Kush Expo in LA
Taking a monster dab during the Kush Expo at LA Center Studios in Los Angeles (October 2012. Got a chance to hang out with the guys from Kush Connection.. HTCC Winners Master Yoda. Fantastic genetics, clean- well processed hash. These guys are what is up in LA.. check them out on W. Pico Blvd. ( Had to re-post due to issues with earlier account).From:theGLReviewViews:0 0ratingsTime:00:58More inPeople Blogs

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Monster Dab @ the Kush Expo in LA - Video

Lot5B Flying H Genetics
From:Katina CosterisanViews:3 0ratingsTime:01:05More inPeople Blogs

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Lot5B Flying H Genetics - Video

Lot5A Flying H Genetics
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Lot5A Flying H Genetics - Video

Lot 25. Binnia Celine - Auctions Plus Progressive Genetics Sale
Lot 25 Binnia Celine - Auctions Plus Progressive Genetics Sale Well bred mare, solid foundation bloodlines. Good sensible low maintenance mare, easy breeder. All of her foals are quiet, with good conformation. Joined to top campdrafter, Chevin Ivory ASHS 140917 More Information: localmedia.auctionsplus.com.au http://www.landmark-classic.com.au Sale on Auctions Plus 10th December 2012From:LandmarkEquineViews:0 0ratingsTime:01:00More inSports

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Lot 25. Binnia Celine - Auctions Plus Progressive Genetics Sale - Video

Lot 14. Scroll Dee Maggy - Auctions Plus Progressive Genetics Sale
Lot 14. Scroll Dee Maggy - Auctions Plus Progressive Genetics Sale Exceptional broodmare that is real easy to breed Maggy has a filly foal at foot by Campdraft and Challenge winning sire Destination Unknown, AQHA Q-45790 ASHS C2-160782 (Acres Destiny/Spinnis Golddust) and preg tested in foal again to the same. An outstanding opportunity to purchase a proven broodmare as a 3 in 1 package, with her 2007 filly selling for $12500 -- Landmark Classic Sale and her 2009 filly selling for $7500 -- Fountain of Youth National Yearling Sale. This mare is a sound investment for anyone #39;s breeding program. More Information: Dale Lyons Mobile: 0428 228 819 localmedia.auctionsplus.com.au http://www.landmark-classic.com.au Sale on Auctions Plus 10th December 2012From:LandmarkEquineViews:0 0ratingsTime:00:53More inSports

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Lot 14. Scroll Dee Maggy - Auctions Plus Progressive Genetics Sale - Video

Cute Dog Plays Tug of War Video
Cute Dog Plays Tug of War Video. Khloe wants her Soccer Ball back and will not give up until she wins, she loves her Soccer Ball! Give Khloe a Thumbs Up for being a COOL DOG! Some info on Khloe #39;s Breed, Lhasa-Poo: Breed Group: Mixes and More Height: Varies Weight: 10 to 20 pounds Life Span: 12 to 15 years The Lhasapoo is a cross between a Lhasa Apso and a Poodle, usually a Miniature Poodle. He may have the curly coat of a Poodle or the long, straight coat of a Lhasa Apso, but he always has a cute, alert face, and sturdy body. The Lhasapoo can come in a multitude of solid colors or in a particolor pattern (a color plus white). The Lhasapoo is a crossbreed. Opening your heart and home to a crossbreed is like opening a beautifully wrapped package on your birthday: you never know what #39;s going to be inside. It #39;s often assumed that a crossbreed will combine the best of two or more breeds, but genetics doesn #39;t always work that way. The way genes combine and express themselves is not necessarily in a breeder #39;s control, even less so when two breeds are crossed. That #39;s something to keep in mind before you lay down lots of money for a dog that you have been assured will be hypoallergenic or healthier than a purebred. At their best, Lhasapoos are friendly and affectionate, although some may have the suspicious nature of the Lhasa Apso, whose original purpose was to serve as a temple watchdog. Lhasapoos generally weigh 10 pounds to 20 pounds, making them a comfortable size for most ...From:Mad4ClipsViews:2 1ratingsTime:01:23More inPets Animals

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The Ediculture Course Session 10 Part 2 - SEED SAVING AND GENETICS.wmv
The Ediculture Course Session 10 Part 2 - SEED SAVING AND GENETICS As well as demonstrating competence in all the aspects of growing described on the course and providing potential to secure your food supply in perpetuity, seed saving challenges trends towards uniformity and monopolising nature. Growers need the opposite of commercial qualities - Diversity and local Adaptation, Extended cropping periods and planning for Permanence. This is the tip of the pinnacle of human achievement throughout history! Taste the food of the gods!From:edicultureViews:0 0ratingsTime:39:07More inEducation

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The Ediculture Course Session 10 Part 2 - SEED SAVING AND GENETICS.wmv - Video

Stock Science: Mendelian Genetics
Mr. Stockton talks about Mendel #39;s Pea Plants and the basics of "particulate" genetics.From:Bill StocktonViews:0 0ratingsTime:10:00More inEducation

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Stock Science: Mendelian Genetics - Video

Research commissioned by Marks & Spencer has found that the use of New Zealand sheep genetics could offer sustainability benefits for UK sheep farmers.

The work, which was jointly conducted by the Agri-Food & Biosciences Institute (AFBI) and the College of Agriculture, Food and Rural Enterprise (CAFRE), investigated the merits of using Highlander and Primera sheep breeds in UK sheep flocks to maximise value in the supply chain through increased lamb output and reduced production and processing costs. The study was also supported by Focus Genetics and Linden Foods.

Trials took place on two upland flocks belonging to the Buccleuch Group and compared a typical UK production system of Mule and Texel x Mule ewes, with Highlander and Highlander x Blackface ewes to represent different replacement breeding strategies.

These ewes were crossed with Texel rams, to represent a typical UK terminal sire, as well as UK-bred and NZ-bred Primera rams. Performance was recorded throughout the production and processing cycle, finishing with an evaluation of meat-eating quality using consumer taste panels.

The trial concluded that increasing lamb output and production efficiency by switching from Mule to Highlander ewes offered the opportunity to develop a more sustainable lamb supply chain through reducing on farm costs and greenhouse gas emissions, whilst maintaining product quality, processing efficiency and meat eating quality. Replacing Texel rams with Primera resulted in faster growth rates and a higher proportion of high-value cuts.

Commenting on the results of the trial, AFBI scientist, Dr Ronald Annett, said: "The Highlander ewe showed excellent fertility and rearing ability and the Primera-sired lambs portrayed superior growth rates and had higher wholesale value." "Hopefully this study will make UK farmers think about what drives their returns. It highlights the importance of production efficiency, rather than focusing solely on lamb price or carcass conformation. The trial has demonstrated the importance of maternal genetics in driving production and we hope farmers will take this on board."

Steve McLean, Head of Agriculture & Fisheries Sourcing at M&S, added:

"For a number of years commercial volatility has seen increasing numbers of sheep producers leaving the industry in the UK. We commissioned this work as one of our PaceSetter projects within our Farming for the Future programme. Over the last seven years we have worked with Focus Genetics and a number of UK farmers to try to replicate their successful New Zealand lamb production model in the UK. "We recognise that there are a large number of different production systems in the UK and this trial is simply about establishing baseline information to allow producers to make their own informed decisions on the production model that best suits their farm."

Bayden Wilson, Focus Genetics UK Manager, concluded:

"We welcome the results of the study and hope it will encourage more UK farmers to invest in Focus Genetics breeds. We would like to grow our UK business and we hope farmers will convert after seeing such positive scientific results from New Zealand sheep breeds. As the world seeks more sustainable food production, our genetics are obviously well placed to help farmers improve on-farm efficiency."

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NZ sheep genetics could improve UK sheep industry - research

Gene Therapy for Eye Diseases - Dr. Donald J. D #39;Amico
Donald J. D #39;Amico, MD, the Ophthalmologist-in-Chief at NewYork-Presbyterian/Weill Cornell Medical Center, talks about gene therapy as a potential treatment for eye diseases. You can learn more about Dr. D #39;Amico at: nyp.orgFrom:newyorkpresbyterianViews:0 0ratingsTime:01:55More inScience Technology

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Gene Therapy for Eye Diseases - Dr. Donald J. D'Amico - Video