Archive for the ‘Gene Therapy Research’ Category

Genetic Engineering Of Mesenchymal Stem Cells
ll4.me Genetic Engineering Of Mesenchymal Stem Cells 1. Mesenchymal Stem Cell Engineering and Transplantation: An introduction; F. Aerts, G. Wagemaker- 2. Establishment and Transduction of primary human Stromal/Mesenchymal Stem Cell Monolayers; T. Meyerrose, I. Rosova, m. Dao, P. Herrbrich, G. Bauer, JA Nolta- 3. Gene Expression Profiles of Mesenchymal Stem Cells; DG Phinney- 4. In Vivo Homing and Regeneration of freshly isolated and culture Murine Mesenchymal Stem Cells; RE Ploemacher- 5. Non-human primate models of Mesenchymal Stem Cell Transplantation; SM Devine, R. Hoffman- 6. Engineering of Human Adipose-derived Mesenchymal Stem-like Cells; JK Fraser, M. Zhu, B. Strem, MH Hedrick- 7. Uncommitted Progenitors in Cultures of Bone Marrow-derived Mesenchymal Stem Cells; JJ Minguell, A. Rices, WD Sierralta- 8. Bone Marrow Mesenchymal Stem Cell Transplantation for Children with severe Osteogenesis Imperfecta; EM Horwitz, PL Gordon- 9. Clinical Trials of Human Mesenchymal Stem Cells to support Hematopoietic Stem Cell Transplantation; ON Ko EAN/ISBN : 9781402039591 Publisher(s): Springer Netherlands Discussed keywords: Stammzelle Format: ePub/PDF Author(s): Nolta, Jan A. 1. Mesenchymal Stem Cell Engineering and Transplantation: An introduction; F. Aerts, G. Wagemaker- 2. Establishment and Transduction of primary human Stromal/Mesenchymal Stem Cell Monolayers; T. MeyerFrom:jonibishop696Views:0 0ratingsTime:00:12More inPeople Blogs

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Precarious World - Steve Quayle - Coast to Coast AM Classic
http://www.jetnews.us Date: 01-06-11 Host: George Noory Guests: Steve Quayle Author and researcher Steve Quayle riffed on a variety of topics such as giants, weather modification, secret aircraft, biblical prophecy, genetic engineering, the Illuminati agenda, and Planet X. The machinery to affect weather has gotten smaller and cheaper over the years, and there are currently 72 ionospheric heaters, in addition climate-controlling technology like Project HAARP, he outlined. Sightings of silent triangular-shaped craft are on the rise, and a battle in outer space is imminent, said Quayle, naming "extra-dimensionals" and black-ops as some of the participants. The "super-soldier" program, Stargate technology, and CERN are involved in efforts to re-animate ancient giants, who were some 12-18 ft. height, he declared. "We are experiencing now the full implementation, in my opinion, of the Luciferian war on humanity. We talk about the New World Order, the Illuminati, the International League, but what is the prime directive of all those entities? It #39;s the destruction of a five and half billion people," he cautioned. Quayle reported his recent conversation with a "high ranking Goldman Sachs official" who #39;d visited one of the elite #39;s underground cities that was being prepared. The official warned him that a "global flu" had already been determined, and a mandatory vaccination will be required, with those who refuse to take it being sent to FEMA camps. On the subject of Planet X, Quayle ...From:C2CPlanetViews:17 3ratingsTime:01:53:01More inEducation

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Precarious World - Steve Quayle - Coast to Coast AM Classic - Video

Public release date: 16-Nov-2012 [ | E-mail | Share ]

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 x2156 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, November 15, 2012Epstein-Barr virus (EBV) is the cause of infectious mononucleosis and a risk for serious disease in liver transplant recipients. Molecular tests that can identify early protein markers produced by EBV may have value for diagnosing active infection. The benefits of this diagnostic approach in patients with mononucleosis and in EBV-infected transplant patients are evaluated in an article published in BioResearch Open Access, a bimonthly peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers. The article is available free on the BioResearch Open Access website.

Andrea Crowley, Jeff Connell, Kirsten Schaffer, William Halla, and Jaythoon Hassan, University College Dublin and St. Vincent's University Hospital, Dublin, Ireland, compared three immunoassay methods for detecting antibodies produced by the body in response to EBV infection and the presence of proteins that comprise the EBV early antigen complex. The researchers determined which of the diagnostic tests could better predict EBV infection in patients with mononucleosis or in immunosuppressed adult liver transplant recipients. The article "Is There Diagnostic Value in Detection of Immunoglobulin G Antibodies to the EpsteinBarr Virus Early Antigen?" presents the complete methodology and results of this study.

"Having the ability to predict the risk of developing EBV-induced lymphoproliferative disorders after a transplant has important consequences for patient care, as it would allow for prompt therapy and could potentially decrease patient mortality," says Editor-in-Chief Jane Taylor, PhD, MRC Centre for Regenerative Medicine, University of Edinburgh, Scotland.

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About the Journal

BioResearch Open Access is a bimonthly peer-reviewed open access journal that provides a new rapid-publication forum for a broad range of scientific topics including molecular and cellular biology, tissue engineering and biomaterials, bioengineering, regenerative medicine, stem cells, gene therapy, systems biology, genetics, biochemistry, virology, microbiology, and neuroscience. All articles are published within 4 weeks of acceptance and are fully open access and posted on PubMedCentral. All journal content is available on the BioResearch Open Access website.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Tissue Engineering, Stem Cells and Development, Human Gene Therapy and HGT Methods, and AIDS Research and Human Retroviruses. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 70 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

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Is the detection of early markers of Epstein Barr virus of diagnostic value?

Public release date: 16-Nov-2012 [ | E-mail | Share ]

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, November 13, 2012Following an infection, dysregulation of the immune system can result in a systemic inflammatory response and an often fatal condition called severe sepsis or septic shock. Sepsis is not uncommon, yet its cause and underlying immune dysfunction remain poorly understood. Regulatory T cells (Tregs), a component of the immune system, now appear to have an important role in suppressing the immune response in advance of sepsis, and understanding this role may lead to new therapeutic strategies for improving patient outcomes, as described in a review article in Journal of Interferon & Cytokine Research, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available free online on the Journal of Interferon & Cytokine Research website.

Li-Na Jiang, Yong-Ming Yao, and Zhi-Yong Sheng, Chinese PLA General Hospital, Beijing, and Hebei North University, Zhyangjiakou, China, review the growing body of literature supporting a link between alterations in Treg function and the development of sepsis, based on animal studies and preliminary human studies. In the article "The Role of Regulatory T Cells in the Pathogenesis of Sepsis and Its Clinical Implications (http://online.liebertpub.com/doi/full/10.1089/jir.2011.0080)," the authors suggest that accumulating experimental and clinical evidence indicates that manipulating Tregs may offer a promising strategy for treating patients with septic shock.

"Regulatory T cells are receiving much attention as important determinants of both beneficial and detrimental immune responses," says Co-Editor-in-Chief Thomas A. Hamilton, PhD, Chairman, Department of Immunology, Cleveland Clinic Foundation. "This review brings focus to the function of this important cell population in the context of sepsis, a condition more frequently associated with innate immunity."

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About the Journal

Journal of Interferon & Cytokine Research, led by Co-Editors-in-Chief Ganes C. Sen, PhD, Chairman, Department of Molecular Genetics, Cleveland Clinic Foundation, and Thomas A. Hamilton, PhD, is an authoritative peer-reviewed journal published monthly in print and online that covers all aspects of interferons and cytokines from basic science to clinical applications. Journal of Interferon & Cytokine Research is the official journal of the International Society for Interferon and Cytokine Research. Complete tables of content and a sample issue may be viewed online on the Journal of Interferon & Cytokine Research website.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Viral Immunology, AIDS Research and Human Retroviruses, and DNA and Cell Biology. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 70 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

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Are we closer to understanding the cause of deadly sepsis?

PHILADELPHIA Fifty years ago, UK researcher John Gurdon demonstrated that genetic material from non-reproductive cells could be reprogrammed into an embryonic state when transferred into an egg. In 2006, Kyoto University researcher Shinya Yamanaka expanded on those findings by expressing four proteins in mouse somatic cells to rewind their genetic clocks, converting them into embryonic-like stem cells called induced pluripotent stem cells, or iPS cells.

In early October, Gurdon and Yamanaka were awarded the 2012 Nobel Prize in Physiology or Medicine for their discoveries. Now, thanks to some careful detective work by a team of scientists led by Kenneth Zaret, PhD, at the Perelman School of Medicine, University of Pennsylvania, researchers can better understand just how iPS cells form and why the Yamanaka process is so inefficient, an important step to work out for regenerative medicine. Zaret is associate director of the Penn Institute for Regenerative Medicine and professor of Cell and Developmental Biology.

The findings, which appear in the Nov. 22 issue of the journal Cell, uncover cellular impediments to iPS cell development that, if overcome, could dramatically improve the efficiency and speed of iPS cell generation.

These studies provide detailed insights into how reprogramming factors interact with the chromatin of differentiated cells and start them down the path toward becoming stem cells, said Susan Haynes, PhD, National Institute of General Medical Sciences, which partially funded the work. Dr. Zarets work also identified a major structural roadblock in the chromatin that the factors must overcome in order to bind DNA.This knowledge will help improve the efficiency of reprogramming, which is important for any future therapeutic applications.

Human iPS cells are generated by expressing four DNA-binding proteins Oct4, Sox2, Klf4, and c-Myc (O, S, K, and M) in human non-reproductive, or somatic cells, such as skin cells. These factors have generated intense interest in the stem cell and medical communities, not least because they offer the promise of embryonic stem cells with none of the messy ethical and moral dilemmas. Just as significantly, patient-specific iPS cells from individuals with genetic disorders can be used to study disease origin and to develop drugs for a range of conditions such as Huntingtons and Parkinsons diseases.

Yet, the process of generating iPS cells is highly inefficient. It can take a month to fully reprogram somatic cells into iPS cells, and as few as one in 10,000 cells that take up the four factors will successfully convert. Whats more, some studies indicate that, for all their plasticity, iPS cells are not precisely equivalent to embryonic stem cells. Zaret, with Penn postdoctoral fellow Abdenous Soufi, PhD, and bioinformatician Greg Donahue, PhD, decided to find out why.

The team analyzed the destination in the human genome of the four reprogramming factors 48 hours after the initiation of iPS cell reprogramming and compared those locations to four cell types: the starting cell population; the fully reprogrammed iPS cells; cells nearing the end of the reprogramming process (pre-iPS); and embryonic stem cells.

They found that at 48 hours the factors tended to bind gene regulatory elements called enhancers, far removed from the genes they regulate, rather than the target genes themselves. That suggests that O, S, and K serve as pioneer factors that open closed chromatin structures on the DNA itself, facilitating the reprogramming process by making target sections of the genome available to be read by messenger RNA.

The team also found large regions of the genome that were refractory to the binding of reprogramming factors at 48 hours, but which were eventually activated in, and are in fact required, for the formation of iPS cells.

Basically, large chunks of the human genome were physically resisting these factors from entering, Zaret explained. That provided some understanding that youve got to overcome the binding impediment to get these factors to their final destination.

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Penn Study Decodes Molecular Mechanisms Underlying Stem Cell Reprogramming

Public release date: 15-Nov-2012 [ | E-mail | Share ]

Contact: Karin Eskenazi ket2116@columbia.edu 212-342-0508 Columbia University Medical Center

New York, NY (November 15, 2012) About 10 percent of kids born with kidney defects have large alterations in their genomes known to be linked with neurodevelopmental delay and mental illness, a new study by Columbia University Medical Center (CUMC) researchers has shown.

The study was published today in the online edition of the American Journal of Human Genetics.

Congenital defects of the kidney and urinary tract account for nearly 25 percent of all birth defects in the US and are present in about 1 in every 200 births. Eventually, an evaluation for genomic alterations will be part of the standard clinical workup. Patients with congenital kidney diseasewho are currently lumped into one categorywill be placed in subgroups based on their genetic mutations and receive a more precise diagnosis.

"This changes the way we should handle these kids," said kidney specialist Ali Gharavi, MD, associate professor of medicine at CUMC, associate director of the Division of Nephrology, and an internist and nephrologist at NewYork-Presbyterian Hospital.

"If a physician sees a child with a kidney malformation, that is a warning sign that the child has a genomic disorder that should be looked at immediately because of the risk of neurodevelopmental delay or mental illness later in life," he said. "This is a major opportunity for personalizing medical care. As we learn which therapies work best for each subgroup, the underlying genetic defect of the patient will dictate what approach to take."

The current study was the result of a large collaborative effort of CUMC and other medical centers in the US, Italy, Poland, Croatia, Macedonia, and the Czech Republic. It was led by Dr. Gharavi and his colleague Simone Sanna-Cherchi, MD, an associate research scientist in CUMC's Department of Medicine.

Until now, no studies have linked congenital kidney disease with neurodevelopmental disorders.

"If you talk to clinicians, they tell you that some of these kids behave differently," Dr. Sanna-Cherchi said. "There has been a general assumption, though, that behavioral or cognitive issues in children with chronic illnesses such as kidney disease stem from the child's difficulty in coping with the illness. Our study suggests that in some cases, neurodevelopmental issues may be attributable to an underlying genomic disorder, not the kidney disease."

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Surprising genetic link between kidney defects and neurodevelopmental disorders in kids

Editor's Choice Main Category: Urology / Nephrology Also Included In: Pediatrics / Children's Health;Genetics Article Date: 16 Nov 2012 - 10:00 PST

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Around 10 percent of kids with kidney defects have these mutations in their genomes, also known to be associated with mental illness and neurodevelopmental delay.

Congenital urinary tract and kidney defects make up about 25 percent of all birth defects in the United States and are found in one in every 200 births.

At last, an analysis for genomic alterations will be included in standard clinical workup. Patients who have congenital kidney disorder, presently included in one group, will be put into subcategories according to their genetic mutations, resulting in a more specific diagnosis.

Kidney specialist Ali Gharavi, MD, associate professor of medicine at CUMC, associate director of the Division of Nephrology, and an internist and nephrologist at NewYork-Presbyterian Hospital says:

This study was a broad collaboration of CUMC and other medical centers worldwide. Up until this point, no studies have successfully connected congenital kidney disease with neurodevelopmental disorders.

Simone Sanna-Cherchi, MD, an associate research scientist in CUMC's Department of Medicine explains:

Nearly 20 percent of kidney defects come from big DNA mutations. The mutations identified by Drs. Gharavi and Sanna-Cherchi and their team, are in a class of mutations known as copy number variations (CNVs).

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Genetic Link Found In Children With Kidney Defects And Neurodevelopmental Disorders

A patient receives an ultrasound before a new genetic test for potential fetus abnormalities Oct. 4 at obstetrician Susan Klugman's office in Scarsdale, N.Y.(Photo: Carucha L. Meuse, The (Westchester, N.Y.) Journal News)

WESTCHESTER, N. Y. -- A new test, called chromosomal microarray technology, is providing doctors and prospective parents with more information than ever before about the genetic makeup of a baby still in the womb.

But what that knowledge actually means is not always clear, causing confusion and anxiety for parents and physicians.

Michelle Catalano had no reason to think her fourth baby wouldn't be born as healthy as her other three.

But because the Eastchester, N.Y., resident was 36 -- a year into the territory obstetricians ominously describe as "advanced maternal age" -- she was given the option of using the new technology to test whether her baby was developing free of genetic defects that could signal trouble.

"It's an evolving technology," said David Kronn, chief of medical genetics at Maria Fareri Children's Hospital at Westchester Medical Center in Valhalla, N.Y. The results, he said, aren't always cut and dried.

Susan Klugman, an obstetrician in Larchmont and Yonkers, N.Y., and 300 of her patients recently took part in a nationwide study of chromosomal microarray technology to determine how effective the method is.

"This zooms down and looks at the specific genetic material in the chromosomes to make sure nothing is missing or nothing is extra," said Klugman, director of reproductive genetics at Montefiore Medical Center and an associate professor at Albert Einstein College of Medicine.

Initial results of the study submitted early this year at the Society for Maternal-Fetal Medicine showed that prenatal chromosomal microarray technology can detect more genetic abnormalities than current methods.

Klugman now offers the test to select patients in her practice.

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New genetic test provides precise, yet hazy results

Bacterial And Bacteriophage Genetics
ll4.me Bacterial And Bacteriophage Genetics EAN/ISBN : 9780387314891 Publisher(s): Springer, Berlin, Springer, New York Format: ePub/PDF Author(s): Birge, Edward A. EAN/ISBN : 9780387314891 Publisher(s): Springer, Berlin, Springer, New York Format: ePub/PDF Author(s): Birge, Edward A.From:melissaroberts9865Views:0 0ratingsTime:00:13More inPeople Blogs

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REVENGE IS SWEET (The Hidden: Source)
Hey Guys! Shady Here! Download Here: http://www.hidden-source.com Thanks for watching and if you don #39;t know what the hidden is... "In the early 1950s human genetics experimentation was taking its first, tentative steps. Amongst many other black projects, a team of British scientists working at an Infinitum Research experimental station stumbled across some remarkable phenomena involving DNA manipulation. This led to deeper research with dangerously unpredictable results, often leading to human patients losing their lives in irresponsible and immoral experiments. Time passed on, and by the mid 1990s the failure rate of the experiments had been reduced from 75% to a mere 15%, enough for Infinitum to move onto the next stage: Biological Light Refraction. The British team were hoping to unravel the possibilities of light manipulation to create the perfect covert military agent. Early into the new millennium, due to a gross miscalculation, a series of tests on Subject 617 led to a massive synaptic trauma leaving the patient with multiple genetic anomalies. The subject was left in constant pain and with unstable DNA. The subject escaped captivity, killing anyone that got in its way. The IRIS (Infinitum Research Interception Squad) team have been deployed to return the subject to a maximum security Infinitum Research facility for further study and dissection. The entire project was considered a failure: all funding ceased and development was discontinued while all records and traces of ...From:TheShadesofPALEViews:27 1ratingsTime:03:47More inGaming

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REVENGE IS SWEET (The Hidden: Source) - Video

Handbook On Immunosenescence
ll4.me Handbook On Immunosenescence 1. Immunosenescence.- 2. Methods and models for studying immunosenescence.- 3. Cellular immunosenescence. 3.1 T cells. 3.2. B cells. 3.3 Neutrophils. 3.4 Antigen presenting cells. 3.5 NK and NKT cells. 3.6. Stem cells. 3.7. Genetics.- 4. Mechanisms4.1. Receptors and signal transduction. 4.2 Mitochondria. 4.3 Proteasome. 4.4 Cytokines. 4.5 Neuro-endocrine-immune Network. 4.6 Thymus. 4.7. Inflammation.- 5. Clinical relevance in disease states. 5.1 Infection. 5.2 Autoimmunity. 5.3 Cancer. 5.4 Metabolic syndrome. 5.5. Neurodegenerative diseases. 5.6 Frailty. 5.7. Osteoporosis.- 6. Modulation. 6.1 Nutrition. 6.2. Lipids. 6.3. Vaccination. 6.4. Can interventions to influence immunosenescence succeed? Subject Index. EAN/ISBN : 9781402090639 Publisher(s): Springer Netherlands Discussed keywords: Immunologie Format: ePub/PDF Author(s): Fulop, Tamas - Franceschi, Claudio - Hirokawa, Katsuiku 1. Immunosenescence.- 2. Methods and models for studying immunosenescence.- 3. Cellular immunosenescence. 3.1 T cells. 3.2. B cells. 3.3 Neutrophils. 3.4 Antigen presenting cells. 3.5 NK and NKT cellsFrom:aaronrogers9865Views:0 0ratingsTime:00:16More inPeople Blogs

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Molecular Diagnostics
ll4.me Molecular Diagnostics Key Features #65533; Contains state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders #65533; Includes in-depth discussion of ethical and safety considerations #65533; Identifies genetically modified organisms (GMO #39;s) #65533; Covers forensic analysis and every-day issues in a diagnostic laboratoryDescriptionThe second edition of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited disease. The book delves further into the principle and brief description of the technique, followed by examples from the authors #39; own expertise. Contributors to the 2/e are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. Molecular Diagnostics, 2/e , is a needed resource for graduate students, researchers, physicians and practicing scientists in molecular genetics; professionals from similar backgrounds working in diagnostic laboratories in academia or industry, as well as, academic institutions and hospital libraries.RELATED TITLES:Trent/Molecular Medicine, April 2005,$79.95, 0-12-699057-3 Innis (1999) PCR Applications, HB, $89.95,0-12-372185-7, PB, $66.95,Key Features:*Deals exclusively with the currently used molecular biology techniques to identify the underlying molecular defect of inherited diseases*Includes ...From:melissafudge9865Views:0 0ratingsTime:00:13More inPeople Blogs

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Wes Jackson: The Land Institute
Wes Jackson, President of The Land Institute, was born in 1936 on a farm near Topeka, Kansas. After attending Kansas Wesleyan (BA Biology, 1958), he studied botany (MA University of Kansas, 1960) and genetics (Ph.D. North Carolina State University, 1967). He was a professor of biology at Kansas Wesleyan and later established the Environmental Studies department at California State University, Sacramento, where he became a tenured full professor. He resigned that position in 1976 and returned to Kansas to found The Land Institute. Dr. Jackson #39;s writings include both papers and books. His most recent works, Nature as Measure (2011) and Consulting the Genius of the Place: An Ecological Approach to a New Agriculture (2010), were both published by Counterpoint Press. The Virtues of Ignorance: Complexity, Sustainability, and the Limits of Knowledge (2008) and Rooted in the Land: Essays on Community and Place (1996), were co-edited with William Vitek. Becoming Native to This Place, 1994, sketches his vision for the resettlement of America #39;s rural communities. Altars of Unhewn Stone appeared in 1987 and Meeting the Expectations of the Land, edited with Wendell Berry and Bruce Colman, was published in 1984. New Roots for Agriculture, 1980, outlines the basis for the agricultural research at The Land Institute. The work of The Land Institute has been featured extensively in the popular media including The Atlantic Monthly, Audubon, National Geographic, Time Magazine, The MacNeil ...From:TEDxTalksViews:0 0ratingsTime:18:21More inScience Technology

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Obamacare Origin of Nazi Holocaust - Eugenics / Euthanesia
Few may realize it, but the Holocaust started in the national healthcare system of Germany with a project called the T4 program. It began with the idea that the distribution of healthcare should be based on the welfare of society, according to Government priorities. Hitler ordered the hospitals and mental institutions to euthanize hundreds of thousands of the handicapped and mentally ill, in order to save money. In any universal healthcare system the Government will be deciding at some level, who gets healthcare and who doesn #39;t, that is, who lives and who dies. Much of the early work in Eugenics was done in the United States and Hitler was inspired by the work by of American scientists. Eugenics is the idea that Government can improve that health of the population by making decisions that change the genetics of the population. The German government decided that the Jewish race is genetically inferior and their genes should be eliminated from the population. Many of the techniques used in the extermination of the Jews were developed in the hospitals of the German universal healthcare system. Following is an excerpt of a documentary on the Nazi T4 program. Obamacare Eugenics -- Why the Government should NOT Control Healthcare! stop-obama-now.netFrom:SoNSanDiegoViews:73 4ratingsTime:03:37More inNews Politics

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Obamacare

Quark Expeditions: Q A with Dr. Tom Hart, Penguinologist - Part 2
Part 2 of our webinar with Tom Hart, Penguinologist. Apologies for the low audio. Dr. Tom Hart will be part of the Expert In Residence program on the following Quark Expeditions voyages: November-22-30 2012 Introduction to Antarctica: The White Continent November-30-Dec-09 2012 Antarctic Explorer: The Classic Adventure December-09-18 2012 Antarctic Explorer: The Classic Adventure December-18-27 2012 Antarctic Explorer: The Classic Adventure December-27 2012- January-14 2013 Falklands, South Georgia and Antarctica: Explorers and Kings About Dr. Tom Hart: Tom runs the Penguin Lifelines project at Oxford University and the Zoological Society of London, through which he monitors Antarctic wildlife using camera trapping, volunteer photos and population genetics. Tom #39;s PhD at Imperial College and the British Antarctic Survey investigated penguin foraging behavior around South Georgia. He loves the world #39;s cold places and is passionate about protecting them. Tom loves all penguins, but particularly Macaroni Penguins, as they have the most attitude.From:QuarkExpeditionsViews:2 0ratingsTime:07:09More inPets Animals

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21 y/o Natural Bodybuilder - Polska Genetics and Nikola Gojani: Offseason Posing Update
*SUBSCRIBE AND LIKE* Please check out my Facebook Page for Updates and News!! http://www.facebook.com http://www.facebook.com Intro by. http://www.youtube.com Music produced by: http://www.myspace.comFrom:mousch66Views:2078 74ratingsTime:07:44More inSports

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21 y/o Natural Bodybuilder - Polska Genetics and Nikola Gojani: Offseason Posing Update - Video

Angus and a few BWF heifers
These ladies possess some of the best Genetics in the Beef Industry. They are sired by Conneally Angus Bulls out of Commercial Angus cows they are bred to Stevenson Basin Angus Bulls. They will start calving the first week of Feb. and should be calved out in 6-8 weeks. Clay 9795416703From:cowboysales1Views:3 0ratingsTime:01:20More inPets Animals

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Joesph Salama - author of "The Paleo Miracle", a book showing that food is medicine
From three weeks into his paleo transformation, Joseph Salama was so inspired by his health and happiness level that he began sharing it with his friends and family - with smashing success, helping his mother with her type II diabetes and his father with his Parkinson #39;s. By the end of ten months, he had over 80 converts under his belt - all of whom reported improved health, weight loss, and more energy and vigor than they had felt in years. But that wasn #39;t enough. So he sought out and contacted hundreds of others who have transformed, and selected the best stories to share with the rest of the world in a book, "The Paleo Miracle, 50 stories of change and found health. When he isn #39;t working on paleo books, Joseph is busy being a father, a trial attorney, and a mediator in the San Francisco Bay Area, and sits on the Board of Directors for several non-profit organizations. What is the Paleo Diet and why The Paleo Miracle book? Do you think that weight gain and disease are simply a function of age and genetics? Do you wonder why, despite eating a whole-grain, low-fat diet and putting in countless hours of exercise, you aren #39;t getting any thinner? Most importantly: Why do you eat the way you do? Because someone else told you that it is healthy? In the paleo community, we believe that FOOD IS MEDICINE. We have either eliminated all symptoms of, or dramatically improved, the diseases we had by eating REAL food - diseases like diabetes, heart disease, ADHD, Crohn #39;s, and many ...From:Bill VickViews:4 1ratingsTime:13:58More inPeople Blogs

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Origin of so called Caucasian Race
Similarities = Same Proto-Indo-European Language Group, Same Spinal Facial Structure, Skull Structure, Social and Linguistic Similiraties between DESI (south Asian, ie Pakistan, India, Sri Lanka, Bangladesh) and Northern Europeans... South Europeans from Spain, Italy, and France, are not strictly Aryans, Because are mixed between The Albino Desi #39;s and Semetics... whilst DESI #39;s are seperate from Arab and are a pure genetic group. East Asians geographically have a harder place to mix genetics,.. white, black, big brother, indian, people, albino, science, origin, life, environment, home, racism, race, nation, entertainment, televisino, culture, celebs, hollywood, society, tech, gadget, android, google, iphone, albinism. and more... Its not racist its actually the opposite of racism, but its definatly an eye opener South Europeans are NOT #65279; linked with North Europeans... South Europeans are semetic, with Afro-Asiatic mix... North are Pure INDO-europeans South Europeans genetics mutated #65279; from African Albinos.... Semetic North European genetics mutated from Indian Albinos ...... Indo-European.From:JayEther9Views:0 0ratingsTime:05:26More inEducation

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Origin of so called Caucasian Race - Video

Gregory Stock - Aging: The Disease, The Cure, The Implications
Gregory Stock is a biophysicist, best-selling author, biotech entrepreneur, and the director of the Program on Medicine, Technology and Society at UCLA #39;s School of Medicine. He has written extensively on the implications for society, medicine and business of the human genome project and associated developments in molecular genetics and bioinformatics. His interests lie in the scientific and evolutionary as well as ethical, social and political implications of today #39;s revolutions in the life sciences and in information technology and computers. He has dealt with topics relating to privacy issues in healthcare and genomics; advances in reproductive biology and embryo screening; future possibilities in human germline engineering and anti-aging interventions; and scenarios of future human evolution. Stock #39;s speeches, writings and positions reflect a vision of pragmatism if not enthusiasm about adapting to the profound and difficult shifts these new technologies will bring and avoiding unnecessary delay in the development of new therapeutics and medical and biological interventions emerging from progress in the life sciences. Stock also is the CEO of Signum Biosciences, a biotech company developing therapeutics for Alzheimer #39;s and other diseases as well as health and wellness agents. He sits on the editorial board of the American Journal of Bioethics and is in the department of Pediatrics at the UCLA School of Medicine. He is a member of the Board of Directors of Napo ...From:Jeriaska JeriaskaViews:0 0ratingsTime:20:45More inEntertainment

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Gregory Stock - Aging: The Disease, The Cure, The Implications - Video

Bernard Siegel - Aging: The Disease, The Cure, The Implications
Bernard Siegel is the full-time Executive Director of the nonprofit Genetics Policy Institute (GPI) based in Palm Beach Gardens, Florida. He received his undergraduate and law degrees from the University of Miami (BA 1972, JD 1975). He is a member of the Florida Bar since 1975. In 2002, Mr. Siegel filed the landmark case seeking a guardian for the alleged clone, "Baby Eve." The case was widely credited for exposing Clonaid , the so-called "human cloning company" as a sham. In 2003, he traded his 30-year courtroom career to found GPI, which leads the global cause in support of stem cell research. He is a recognized policy expert relating to stem cell research, regenerative medicine and cloning. Working with the world #39;s leading stem cell researchers, Mr. Siegel played a pivotal role in protecting the research in the United Nations, which was under the threat of being banned by world treaty. He also works with grassroots activists throughout the United States, educating lawmakers and formulating effective strategies supporting research for cures. Mr. Siegel serves on the board of directors of Americans for Cures and on the advisory boards of the Sabrina Cohen Foundation for Stem Cell Research, The Brooke Ellison Project and Genomics Education Institute. He is a member of the American Society for Bioethics + Humanities. He is a member of the International Society for Stem Cell Research and serves as the co-chair of the ISSCR Governmental Affairs Committee. Mr. Siegel has been ...From:Jeriaska JeriaskaViews:0 0ratingsTime:18:57More inEducation

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Bernard Siegel - Aging: The Disease, The Cure, The Implications - Video

TSG 217 - Transphobia, and the Non-Participation Option
Perry asks us to discuss our reactions to some incidents of transphobia... by every definition have a certainly experienced transphobia, however recently i have begun a stance of non-participation in transphobic situations. i continue simply being. the reason people become trans has everything to do with genetics. there has, for nearly 40 or so years now, been scientifically validated evidence of a region of the brain that in the brains of male identifying individuals is shaped one way, and in female identifying individuals is shaped a different way. in other words science has discovered a part of the brain that determines gender. additionally there is a segment of the brain that determines sexual attractions and how or bodies react to different pheromones, which is not necessarily gender specific. for me knowing that down to my DNA i am a transsexual and resistance is futile is actually really comforting.From:TrannystarGalacticaViews:0 0ratingsTime:04:46More inEducation

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TSG 217 - Transphobia, and the Non-Participation Option - Video

British scientists are to conduct the world's largest study of the genetics behind the lung condition chronic obstructive pulmonary disease (COPD).

Data from 50,000 individuals will be used to determine genetic variants linked to susceptibility to COPD.

In particular, researchers want to see how COPD genes relate to smoking, a major risk factor for the disease.

COPD comprises a group of disorders including chronic bronchitis and emphysema. Each year it affects around 900,000 people in the UK, causes 30,000 deaths, and costs the NHS 500 million.

Details of the new study are being released to mark World COPD Day.

The scientists will draw on the resources of the new UK Biobank, which holds genetic samples as well as health and lifestyle information on half a million volunteers.

Lead researcher Professor Ian Hall, dean of Nottingham Medical School, said: "We currently know very little about why there is such a wide difference in lung health even among smokers. It may have something to do with genetics so we're extremely excited about using the unique resource of the UK Biobank to test this theory."

The work is being funded by the Medical Research Council (MRC). Professor David Lomas, chair of the MRC Population and Systems Medicine Board, said: "We know that smoking is unhealthy for anyone but we know little about why the lungs of most smokers are seriously affected, while those of some seem to stay relatively healthy.

"If we knew more about the genetics that cause this variation we would be better able to direct treatments to those who are most at risk and have an increased chance of developing drugs to target this type of lung disease."

Scientists from the University of Nottingham, the University of Leicester, and St George's, University of London, are taking part in the research.

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Genetics study into lung condition

WASHINGTON--(BUSINESS WIRE)--

Affordable and higher quality food will result from new genetic advances inspired by a unique industry collaboration. Two of the worlds largest animal breeding companies aim to achieve further breakthroughs in the field of genomics during the next three years of a joint development agreement (JDA).

Arkansas-based Cobb-Vantress Inc. and Hendrix Genetics B.V. which is headquartered in Boxmeer in the Netherlands initially set up the JDA in 2008 to share and promote expertise, particularly in the fast-growing field of genomics. Already new genomic selection tools have been discovered and developed, such as the cutting-edge SNP Chip for chickens. This is a glass slide that can analyze between 60,000 and 1 million variations in DNA sequences - or Single Nucleotide Polymorphisms (SNPs) - which act as biological markers and help scientists locate a range of genes associated with disease.

The extended agreement will intensify efforts to develop new tools and discover fresh insights into animal genomics in order to improve breeding programs and help increase world food production.

Dr. Gerard Albers, head of research and technology at Hendrix Genetics, said: This is like two renowned chefs sharing recipes, swapping thoughts and ideas on how to create a perfect dish. There are many ways to create this dish, many ingredients that can be used, and with shared views we are able to come closer to this perfect dish.

The collaboration is the biggest within the animal breeding industry and will produce animals that are more productive, less susceptible to disease and at reduced cost, therefore helping to tackle global food shortages. According to the United Nations World Food Program there are 870 million undernourished people in the world today.

The JDA will also strengthen Cobbs leading position in broiler breeding and Hendrix Genetics renowned role in layer hen, turkey, pig and aquaculture genetics, while enabling the two companies to further explore joint venture business opportunities.

Cobb-Vantress is the worlds leading supplier of broiler breeding stock and technical expertise for the chicken meat industry. It has about 2,500 employees and serves the industry in more than 90 countries.

Hendrix Genetics has nearly 2,400 employees worldwide and operations in 24 countries and provides expertise and resources to producers in more than 100 countries.

Jerry Moye, president of Cobb-Vantress, said: The joint efforts of the Hendrix and Cobb R&D teams have provided valuable knowledge for both of our companies. Cobb is excited to continue our partnership with Hendrix Genetics. We look forward to discovering what opportunities may be in our future.

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Lucid PR: COBB-VANTRESS AND HENDRIX GENETICS EXTEND R&D PARTNERSHIP

SEATTLE, WA--(Marketwire - Nov 14, 2012) - Atossa Genetics, Inc. ( NASDAQ : ATOS ) announced today the closing of its initial public offering of 800,000 shares of its common stock at an initial public offering price of $5.00 per share. Atossa Genetics' common stock is traded on the NASDAQ Capital Market under the trading symbol "ATOS."

Dawson James Securities, Inc. acted as the sole book-running manager and lead underwriter for this offering along with ViewTrade Securities, Inc. and Paulson Investment Company.

A copy of the final prospectus relating to the offering may be obtained by contacting Monique Maclaren of Dawson James Securities, Inc. at (561) 391-5555 or by emailing mmaclaren@dawsonjames.com or by standard mail at 925 S. Federal Highway, Suite 600, Boca Raton, FL 33432. You may also obtain these documents for free by visiting EDGAR on the SEC's website at http://www.sec.gov.

A registration statement relating to these securities was declared effective by the Securities and Exchange Commission on November 7, 2012. This offering was made solely by means of a prospectus. This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or other jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

About Atossa Genetics, Inc.

Atossa Genetics, Inc., The Breast Health Company, is based in Seattle, Washington, and is focused on the prevention of breast cancer through the commercialization of diagnostic medical devices and tests that can detect precursors to breast cancer, and through research and development that will permit it to commercialize treatments for pre-cancerous lesions.

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Atossa Genetics, Inc. Announces Closing of Initial Public Offering