Archive for the ‘Hormone Clinic’ Category

publication date: May. 29, 2020

By Alexandria Carolan

This story is part of The Cancer Letters ongoing coverage of COVID-19s impact on oncology. A full list of our coverage, as well as the latest meeting cancellations, is availablehere.

Radiation visitsmuch like preventative screenings, surgery, chemotherapy and screeningwere delayed or canceled at the peak of COVID-19 in the United States.

Now, the patients are returning, in some cases creating small upticks in demand for treatments that were delayed in March, April and May. In a few institutions, the return of the patients is creating wich-welcomed backlogs.

In a survey conducted by the American Society for Radiation Oncology April 16-30, 85% of oncology practices said radiation oncology appointments at their practices had decreased by about a third, even though their doors remained open through the pandemic. ASTRO received responses from 222 physician leaders of radiation oncology practices.

In the survey, 82% of respondents cited delayed/deferred treatment and 81% cited decreases in the number of patients being referred for radiation therapy.

On average, radiation oncology practices reported seeing two-thirds of their typical patient volume in late April. Source: ASTRO.

What were trying to do with the survey data is to dive deeper into that. We dont have the answers yet, because we simply are still collecting the data. But one of the questions we do want to ask isif there is a differential impact of COVID specific to cancer care, and to radiation delivery, that may or may not require some kind of policy-level intervention, or practice-level intervention, David Schwartz, co-author of the ASTRO study, said to The Cancer Letter.

This is where its now a global, community-wide freakout. What impacts some of these things is not just the physicians, nor even the diseaseits also the patient and communitys response to an overwhelming threat. Youre seeing people not showing up for surveillance, said Schwartz, professor and chair of the Department of Radiation Oncology at University of Tennessee Health Science Center.

Data from another survey, conducted by the American Cancer Society Cancer Action Network, showed that 79% of patients in active cancer treatment reported a delay to their health care (up from 27% in a previous survey). Seventeen percent of patients in active treatment reported delays to their cancer therapychemotherapy, radiation, or hormone therapy. The survey polled more than 1,200 cancer patients and survivors.

There are certain feeder cancers that keep the radiation oncology units busy. Those need to be diagnosed as a process. That process was brokenis broken, Len Lichtenfeld, deputy chief medical officer at ACS, said to The Cancer Letter. A breast cancer patient needs radiation following a lumpectomy, a prostatectomy that needs radiation, lung cancer patients that may benefit from radiation.

In the ACS CAN survey, 17% reported that the threat of COVID-19 prevented them from seeing a doctor for an illness or injury for which they would have otherwise sought treatment. Among those who delayed or canceled care, 59% said the decision was made by their health care provider.

Nearly half (46%) of cancer patients and survivors reported a deterioration to their financial situation that affected their ability to pay for care, an increase from 38% in the ACS CAN survey released in April.

What were going to see is a backlog of more advanced presentations in the future, with patients whose care has been affected and delayed by the pandemic, Sue S. Yom, professor in the Departments of Radiation Oncology and Otolaryngology-Head and Neck Surgery at University of California, San Francisco, said to The Cancer Letter.

Radiation oncology is unique in that it requires such a specific commitment of time and resources over a very intensive period. I dont think that that is something that all patients have the ability to do right now, Yom said.

The uptick in demand for services is especially dramatic at New Yorks Mount Sinai Health System. Mount Sinai deferred appointments at the beginning of the crisis, and made room in its hospitals for an expected overflow of COVID-19 cases in the city. That overflow never came.

We have some outpatient facilities that patients were able to go to. Once we realized we were on the other side of the peak, and there wasnt really going to be a need to use our clinical areas, we started opening them up again and ramping up, Kenneth Rosenzweig, professor and system chair of radiation oncology at Mount Sinai Health System, said to The Cancer Letter.

As of today, the end of May, were actually at a higher volume of patients on treatment than our typical average, Rosenzweig said. I think part of that, another reason is that some of the patients who had been delayed are now on treatment. So, there was a bit of a backlogand now thats opened up.

Radiation appointments at Memorial Sloan Kettering Cancer Center plummeted during the peak of COVID-19. Now, MSK is seeing increases in radiation oncology appointments.

It was certainly expected that during that time where you would see, particularly in Aprilwhen the incidence [of COVID-19] was so high here, and we were seeing the ER flooded with patientsthat we would see a reduction in radiation oncology visits, Daniel Gomez, director of thoracic radiation oncology, and chief of radiation oncology, Manhattan Service, at MSK, said to The Cancer Letter.

Now that thats subsided, youre seeing the opposite effect, and with regard to patients wanting to come in and get their cancers treated.

On a policy level in the U.S., it is up to the states and counties to institute COVID-19 guidelines.

As the country learns how to deal with thisin policies, were downstream with those things. What might be going up in Tennessee might not be going up in New York or Chicago, Daniel V. Wakefield, co-author of the ASTRO survey, said to The Cancer Letter.

What well see as a patchwork quilt of changes based on local government ordinances across the country, on not just a state level, but really, on city-to-city level, said Wakefield, chief resident in the Department of Radiation Oncology at University of Tennessee Health Science Center and MPH 20 candidate at Harvard University.

Cancer hospitals are a part of this patchwork quilt.

What you are seeing is different phases of a pandemic. Everyones been in different acute and recovery phases, UCSFs Yom said. And I will say that now that San Francisco is sort of officially in reopening and recovery, we definitely are seeing a very dramatic uptick in our consultations. But, remember, the time from consultation to initiation of treatment can be a week to several weeks.

What were seeing now isnt reflected yet, but our numbers have been trending up for about the past week or two.

Many cancer experts have pointed out that COVID-19 has exacerbated health disparities, making the underserved more underserved (The Cancer Letter, May 22).

The maps that we see of COVID infection rate positivity can actually be overlayed onto cancer incidence and cancer mortality, said Schwartz, who is also in charge of COVID-19 testing and data collection in Memphis. It comes down to one overriding issue: social determinants of health.

This can be manifested as cancer, but also as chronic disease. And thats another issue that we see here in Memphisis that cancer incidences also overlap very tightly with the incidence of hypertension, especially uncontrolled hypertension, diabetes, stroke, heart attack, obesity, food insecurityall of those things, Schwartz said.

David Beyer, medical director of radiation oncology at the Cancer Centers of Northern Arizona Healthcare, has delayed radiation treatments and pivoted to telehealth whenever possible out of concern for the health of his staff and patients.

Beyer is the only physician at his clinic.

We dont know whats going to happen. We dont know who in our department is going to get sick. We are a small rural clinic, Beyer said. If I get sick or have to quarantine myself for two weeks, we have a serious problem. We have two radiation therapy technologists, and they actually deliver the treatments on a day-to-day basis to each patient. We have two of them. If one of them gets sick, or God forbid both of them get sick or have to self-quarantine, we have a problem.

Beyers clinic used to treat 25-30 patients per daynow he sees about 15-20.

There is one place where you can get screening mammograms. They are not doing screening mammograms right now, Beyer said. They made the same choice to shut down routine screening mammography. So, were not seeing breast cancer patients that otherwise mightve been diagnosed right now with an asymptomatic breast cancer.

Still, Beyers location in Sedona has been relatively spared from the coronavirus. As of May 25, his local hospital had one confirmed case of the disease. His staff members have been asking, When are we going to start seeing our new patients in person, instead of over the computer?

My answer is, Not yet, Beyer said. Were still sticking with the telehealth options as much as possible, so that we reduce the risk of exposing us and exposing them.

The next county over is the Navajo Nation. It exploded there. They have one of the highest rates of COVID anywhere in the country right now. Its not that its not closeits not right here. What were doing works right now, for us, Beyer said.

In Memphis, where ASTRO study architects Schwartz and Wakefield treat cancer patients, the spread of COVID-19 has been moderate. Nonetheless, the number of radiation oncology appointments at their clinic has declined.

Ours is a center where we dont have high concentrations of people living on top of each other like New York, or San Francisco, or Washington or Los Angelesand we experienced a much different pandemic, Wakefield said. Ours was more of a slow burn. And to be frank, now I think its starting to have more effect than what we were seeing in New York six weeks ago.

The population in Memphis tends to be poor and rural, Wakefield said. People drive their cars to the clinic rather than walk or take public transportation. High poverty rates and accompanying social risks leave its population and rural practices vulnerable.

In Memphis, there is a rural-urban divide, Schwartz said.

Memphis is in an agricultural area, but it represents the largest metropolitan area in this region of the mid-South. We do get rural populations, and do refer back patients to referral to rural practices, Schwartz said. My impression is that rural practices probably have been struggling, simply because they do depend very much on a steady stream of referrals to maintain the nuts and bolts of their practices.

Now, Schwartz and Wakefield are conducting a follow-up survey for ASTRO. That study is likely to show that demand for radiation oncology is continuing to rise.

Now, as the general relaxing of social distancing and restrictive measures have kind of been released at least to some degree, and the nation slowly returns to business, were starting to see a larger influx of patient numbers, Schwartz said. I also think, probably, the patients are more comfortable to come in.

Whatever loss of volume and losses of referrals that we got, I have to believe that the patients, too, are part of that issue. They simply did not feel comfortable coming in anywhere, let alone to a healthcare facility that was seeing patients with COVID, Schwartz said.

If patients are beginning to receive treatment for cancer that requires radiation after the fact, it may take weeks from there to show up in the data.

The number of cases of cancerthe screening test, the diagnoses, the visits starting with a primary care doctor, maybe a urologistall of those visits are way down, ACSs Lichtenfeld said. The normal progress of activity starts with diagnosis, and the treatment. And consequently, if the diagnoses are decreased because people arent going to see the doctor, then I wouldnt be surprised to see that radiation therapy is decreased.

One of the major messages thats been so hard to deliver during this pandemic has been, if you have to a or symptom of cancer, you need to see somebody and you need tonotwithstanding concerns about the risk of going to see a doctoryou have to break through that concern and get yourself taken care of.

The rest is here:
Radiation oncology appointments plummeted in the COVID-19 pandemicbut seem to be rising again - The Cancer Letter

As we begin to anticipate eagerly the loosening of the restrictions that have bounded our lives for the past many weeks, Ive been hankering most of all for resuming hugs with my grandchildren. All my friends who are blessed with being grandparents have been talking throughout the period of quarantine about their feelings of longing for the embrace of the kids.

It turns out that physical contact is a real need; it is vital for mental, emotional, and also physical health. Human beings are wired for contact. People who live alone as I do since the death of my husband three and a half years ago are starved for touch. An article that I read in Healthline makes clear that this deprivation doesnt apply only to sensual touch any and all positive touch is considered to be beneficial. Hot showers and rubbing your own feet can go only so far to relieve skin hunger.

In more than two months without physical contact with another person and in the environment of pervasive anxiety, my body has been releasing the stress hormone cortisol and has not enjoyed the release of oxytocin, sometimes called the love or cuddle hormone; its effects include increasing bonding and trust, which have been in short supply during this period of isolation. Thankfully, the two-dimensional social contacts enjoyed through Zoom meetings and FaceTime have countered the deprivation to some extent. But our bodies know that its not the same.

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After about two weeks into the restrictions, a package that I hadnt ordered arrived for me. My adult daughters had sent me an adorable stuffed animal, a Gund puppy with a sweet face and a soft body. They wanted me to have something to hug, and Im not embarrassed to admit that this sweet little dog has found a place on the pillow next to mine.

The mandated social distance exacerbated a brief emergency that I experienced in the kitchen one evening shortly after Passover. Following several weeks of isolation, my youngest daughter thankfully had recovered from symptoms of covid-19. She had come into my house more than 72 hours after she had tested negative for the virus, and we were being scrupulous to maintain a physical separation between us. I was in the kitchen cutting a bagel, and I carelessly sliced deep into the index finger on my left hand. Blood was gushing. Struggling to rip open the paper wrapping of several Band-Aids and keeping my pulsing, wounded finger under a stream of running cold water, I could hardly manage to wrap it by myself. But there was no way that I could ask for and receive help from my daughter.

My options were limited, because I wouldnt drive over to Holy Name Medical Center when hospital was overwhelmed with serious covid cases, and the nearby urgent care clinic had closed early on a Sunday evening. I had to do it myself, with advice on the phone from an AARP nurse, terrified that contact with another person could invite the disease. In emergency situations fear is especially palpable.

However, throughout the quiet weeks at home without physical contact, Ive had the recurring feeling that something sustaining in my life clearly has been missing.

Im becoming reconciled to the likelihood that some aspects of our earlier social life likely are gone forever. This springtime, most organizations are holding virtual galas on screen, so no handshakes or hugs are possible. But when these events do resume, perhaps by next fall or spring, people are going to hold back from the easy, warm welcomes of old, that involved physical touch. What will be the future of Israeli dance groups, square dancing, and choral singing, where people gather in close proximity? Will acquaintances who abstain from casual contact with people of the opposite sex hold back from supportive pats on the back and sweaty wedding dances with their friends of the same gender, understanding that danger could lurk again in droplets of perspiration? How sad it is that shaking the hand of a colleague will be perceived as a potential threat to well-being yet these are probable lasting legacies of the coronavirus. And after weeks of being cognizant of the need to cultivate compassion, I will keep in mind that there are people near and far who arent able to look forward to the restoration of positive touch in their daily lives.

As summer approaches, well bask in the comfort of cuddles with grandchildren once again, assuming that the kids will be trusting to join the embrace, after months of warnings to keep their distance. Well be able to enjoy the pleasures of a massage or a pedicure and having someone else wash our hair at the salon. Sitting close to friends and loved ones on the sofa while watching a movie and relaxing into a warm hug for several seconds are comforts too long denied that wont be taken for granted for some time to come. The restoration of positive touch is one of lifes blessings, for which we will share words of gratitude with family and friends for having come through the pandemic more or less intact. We could celebrate the first hug of renewed contact by citing the morning blessing of matir asurim, thanking God for setting us free from captivity.

More here:
Yearning to feel human contact once again - The Jewish Standard

A Baldock transgender man has opened up on his battle with alcohol and his mental health as he desperately fights for a body to match his identity.

Kade Mynott, 32, suffered with severe mental health problems as he struggled to come to terms with his true self prior to coming out as transgender.

He also became dependent on alcohol for a number of years before he bravely told his family and friends how he felt.

Now he has started taking testosterone and hopes to soon have top surgery - but NHS waiting times can be long and Kade is having to wear a restrictive chest binder which affects his asthma.

To help, a Go Fund Me page has been set up to raise 8,000 to get Kade the surgery he so desperately wants.

Kade has now courageously shared his story and explained what it has been like to come to terms with his identity:

For the majority of Kade's life so far, he has struggled with his identity and his mental health.

Talking about his experience, he said: "I've struggled for a long time with mental health issues and it clouded my judgements for many years.

"I got into drinking alcohol to deal with my problems so it took me a long time to be able to deal with how I felt.

"I was alcohol dependant for 10 years but I managed to get myself off it after it made my mental health issues worse. I managed to go cold turkey and get myself off alcohol in 2016.

"In the years that followed things started to become a lot clearer about my identity. I didn't manage to come out as transgender until I was age 30 in 2018.

"The whole experience was one of the toughest things I have had to deal with, not knowing who you are is a horrible thing to have to deal with.

"But you add on top the hate you have for yourself and your body for not seeing the outside match the inside.

"I'd shown a lotof signs as a child growing up with having my hair cut short. Even at the age of three I was refusing to wear dresses and skirts and just wanted to wear trousers like all my boy cousins were doing.

"I managed to come out to my mum first - I'm very close to my mum and she is extremely understanding and I'm very lucky to have such a great mum.

"One of my aunties also told me, when I came out, that when I was four I told her I wanted to be a boy. So I guess I have always known but just never knew how to deal with it all.

"My family have been very supportive, my friends have also, which is a great help.

"Like I said, I am extremely lucky to have such a good family around me because I know a lotof people can be the opposite and be disowned for being this way."

Fortunately today, transgender people can now seek help from the NHS in the form of hormone therapies and surgery, and Kade has also managed to get help.

Kade explained: "I went to my GP first to start my journey and she referredme to a NHS Transgender Clinic in London but with such high demand in patients over the past years the waiting lists are just getting longer and longer.

"I've heard there was up to a three or more years waiting time and I was starting to struggle with the dysphoria even more, so I decided to go private to start testosterone treatment.

"I was so happy the day I had the appointment and was told I could start testosterone. I was given Testogel, which was the best option for me as - because of my mental health conditions - the injections could of made my mood more unstable.

A transgender person is someone whose personal idea of their gender does not match with their assigned gender role.

For example a transgender man was born a woman but identifies as a man.

However, under this term, a personal can also identify as a combination of the two sexes or as neither.

Often people who identify as transgender suffer from gender dysphoria where there feel distress because of a mismatch between their biological sex and gender identity.

This is a recognised medical condition and often surgery and hormone treatment as well as psychological support can help with this.

Anyone needing help should see their GP who can refer them to a Gender Identity Clinic (GIC).

More information about gender dysphoria can also be found on the NHS website.

"The effects were slow at first until about the three month mark then my voice started dropping and I'd started getting a lot of body hair growth, and hunger - I wasso hungry all the time!

"I'm only just seven months on testosterone so I've got a lot more to experience yet."

Kade now wants to undergo top surgery but waiting times on the NHS can be long depending on the individual surgeon and clinic.

The waiting time is now affecting Kade and he is desperate to finally feel like his true self.

In a hope to get the surgery quicker, he decided to set up a Go Fund Me page to raise 8,000 to have the surgery privately.

"As I said there is a long waiting list to get an appointment at the NHS gender clinic and even after the first appointment I'd have to wait longer for a second appointment to discuss the option of surgery," he continued.

"It's got too hard waiting especially as you see other parts of your body changing more masculine but there is still obvious signs of being female.

"I'm having to wear binders that restrict my breathing and effect my asthma just to hide my chest.

"I'd be extremely grateful for anyone that donated any money, even the littlest of money helps.

"It would make me so happy to finally be able to live in a body that matches how i feel inside."

Kade also has a message for anyone else who is currently struggling to come to terms with their identity.

He said: "Make sure you talk about it to somebody you think you can trust, just sharing it with someone even if its somebody online takes a big weight off of your shoulders.

"It's okay to be confused and it's okay to not feel like your in the right body you can do things to change it."

The rest is here:
Baldock transgender man's painful battle to live in a body that matches his identity - Hertfordshire Mercury

Medical intervention is required in case you have an irregular menstrual cycle

World Menstrual Hygiene Day is observed on May 28. This day is meant to raise awareness about menstrual hygiene and reduce the taboo around menstruation. Menstruation is a physiological process which is directly related to and responsible for the ability to bear children. The time from the first day of a woman's period to the day before the next period is the menstrual cycle. This cycle of approximately 26-30 days involves a lot of changes that occur in a woman's body in preparation for a pregnancy.

The main reproductive organs in a female are the uterus and two ovaries. The female hormones oestrogen and progesterone rise and fall with the cycle to orchestrate the maturation and release of an egg from the ovary around mid-cycle, which is then implanted in the uterus if it is fertilised by the sperm. Else, the thick lining of the uterus is shed at the end of the cycle in the form of periods. The cycle goes through a series of hormonal changes from day one of the cycle to the 14 day when an egg is released from the ovary and the uterus prepares for pregnancy. Fertility is known to depend on the menstrual cycle.

Also read:Irregular Periods? 5 Possible Reasons Other Than Pregnancy Every Girl Must Know

The menstrual cycle is divided into two phases: the follicular or the first half phase and the luteal phase or the second half. Follicular phase begins on day 1 of the cycle, during which time the hormone oestrogen stimulates the ovaries for growth of eggs, and ends with the ovulation or release of one egg. Luteal phase begins with ovulation during which time progesterone prepares and thickens the lining of the uterus in case of a pregnancy and ends as shedding of this lining or menses in the absence of fertilization.

The length of the follicular phase may vary while that of luteal phase is around 14 days. While the length of the menstrual cycle varies from one woman to another, it usually lasts 287 days.

Each menstrual cycle has a fertile window. This is the period during which women can conceive. In a standard cycle, the fertile window begins 5 days before ovulation and ends on the day of ovulation. While it is difficult to precisely tell when ovulation occurs, most women usually ovulate around 10 to 16 days prior to the next period. The fertile window also varies from cycle to cycle.

Also read:6 Ways To Deal With Excruciating Pain During Periods

The length of your menstrual cycle says a lot.It may serve as a potential indicator of hormonal imbalances and whether ovulation is occurring in a regular manner. A normal length cycle points to regular ovulation while a short or long menstrual cycle suggests that ovulation is either not occurring or occurring irregularly. The fertility rate of women with long or irregular cycles is also decreased.

A shorty cycle usually lasts for less than 21 daysPhoto Credit: iStock

A short cycle, usually less than 21 days, may indicate that ovaries have fewer eggs and may point to imminent menopause. It may also suggest that ovulation is not occurring as it should. If further tests confirm the same, conception may be difficult. A longer cycle (>35 days) also suggests that ovulation is not occurring or is not occurring in a regular manner, thus making conception difficult. Bleeding for a longer period, say more than 7 days, may also suggest that ovulation is not occurring in a regular manner.

Menstrual cycle characteristics therefore appear to have a key link with the fertility potential. Normal menstrual cycle has a robust link with ovulation and fertility potential. If you are in the reproductive age group and wish to conceive but you have irregular menstrual cycles, you must consult a specialist.

Also read:Top 4 Yoga Asanas For Irregular Periods

Irregular or no ovulation decreases the odds of conception without medical intervention. A woman less than 35 years of age with normal cycles who has been unable to conceive after a year of trying should consult a specialist. A woman over 35 with a normal menstrual cycle who has been trying for 6 months and has had no success should also seek a specialist's advice. Normal menstruation indicates regular ovulation, but there may be other reasons for not being able to conceive. As for irregular cycles, we know that ovulation does not occur in a regular manner in such cycles and medical attention is thus required.

(Dr Veena Aggarwal, MD IJCP Group of Publications, Medical Advisor Medtalks.in. She practices in her own clinic in South Delhi)

Disclaimer: The opinions expressed within this article are the personal opinions of the author. NDTV is not responsible for the accuracy, completeness, suitability, or validity of any information on this article. All information is provided on an as-is basis. The information, facts or opinions appearing in the article do not reflect the views of NDTV and NDTV does not assume any responsibility or liability for the same.

Original post:
World Menstrual Hygiene Day 2020: Everything You Need To Know About Your Menstrual Cycle And Fertility - NDTV Doctor

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There are many different types of heart disease, but coronary artery disease, or CAD for short, is the most common. You might also hear it referred to as coronary heart disease or ischemic heart disease, but no matter what you call it, more than 18 million American adults have it, according to the Centers for Disease Control (CDC). And its not just a concern for older folks. Its the number-one killer of both men and women, a sobering 20% of them younger than 65. But there are things you can do, right now, to lower your risk of CAD. Well tell you how.

Coronary artery disease develops when your hearts all-important arteries become damaged. This damage, which happens in a number of ways well soon explain, causes your arteries to dangerously narrow, which can then cause blockages that prevent blood and oxygen from reaching your heart and the rest of your body. (And you probably dont need a website to tell you thats not good.)

Before we get into the nitty-gritty of what causes all those problems, lets do a quick review of how the circulatory system works:

You have arteries throughout your body. Along with your veins and capillaries, they comprise a 60,000-mile-long system of blood vessels.

Your arteries deliver oxygen-rich blood from your heart to every cell in the rest of your body.

Along the way, the blood transfers nutrients and picks up waste products from cells via tiny capillaries, and then it heads back to heart by way of the veins.

Once there, it enters the pulmonary circulatory system. The heart pumps it over to the lungs, where it unloads carbon dioxide and stocks up on a fresh supply of oxygen.

Then it's back over to the heart to do the whole thing again.

Your entire blood supplymore than a gallon of the life-sustaining stuffcycles throughout your body roughly every 30 seconds. Pretty amazing, right?

Whats more, your heart has its own network of arteries to support this critical work. Here are the main players:

In a healthy heart, blood flows unobstructed through the many arteries, providing all that your ticker needs to keep on pumpingand keep you alive. But when CAD develops, serious heart complications can result, including:

The culprit behind CAD is nearly always atherosclerosis. That mouthful of a name describes a process in which plaque builds up over time on the walls of one or more of your hearts arteries. Plaque is a mixture of cholesterol, fat, calcium, and fibrin (a substance that helps your blood to clot), and it tends to collect within the arteries where damage has occurred.

But what damages arteries in the first place?

So, it's like this: When the inside of your arteries get roughed up, it's easier for the plaque-forming compounds to gain a foothold. As it builds up, blood cant flow as easily as it once did. The result? Coronary artery disease.

As CAD progresses, plaque continues to accumulate. Your arteries become increasingly narrow, and you edge closer and closer to heart attack territory. Why? Because heart attacks are caused by partial or complete blockages of blood flow to the heart.

And know this: You dont need a complete blockage for plaque to be life-threatening. Even partially obstructed arteries are a major cause for concern. Why? Because:

Yes. While atherosclerosis is by far and away its most common cause, CAD can also be triggered by the rarer (but still possible) coronary artery spasm. This is also known as non-obstructive coronary artery disease.

Such spasms cause an artery to suddenly tighten, cutting off the flow of blood. They can be triggered by cocaine and nicotine use, or occasionally, severe cold or extreme emotional stress, according to the Mayo Clinic. While such spasms most often occur in people who already have CAD, they can also strike people whose arteries are healthy. For some, a spasm is an isolated event, but in others they occur more than once.

In addition, CAD can also be triggered by other, less-obvious culprits:

Endothelial dysfunction: This is when an artery does not expand to meet the need for increased blood flow, such as during exercise.

Birth defects: Some babies are born with structural damage to their hearts.

Coronary-artery dissection: This is a tear in the wall of one your coronary arteries, which traps blood between the arterial layers. Swelling results, which narrows or blocks the artery to potentially trigger an emergency situation like a heart attack. The reasons for such tears are unknown.

Autoimmune diseases: Conditions that cause chronic inflammation, such as lupus or Crohns disease, can lead to CAD because inflammation damages your arteries, which attracts plaque buildups.

Radiation therapy: This treatment can also cause damage to your arteries, leading to CAD.

A whole host of risk factors bump up your likelihood of developing atherosclerosis and, as a result, your odds of being diagnosed with CAD, as well. The good news? For a substantial number of them, lifestyle changes can make a huge difference. And while some risk factors are unchangeable (like your age and family history), others are within your power to eliminate altogether. Thats because living a healthier lifestyle can help reduce your odds of getting CAD.

Lets first examine the risk factors you cant do anything about (and get 'em out of the way):

Your arteries become more damage-prone the older you get. Its just part of the regular wear and tear of living. Youre most likely to develop CAD after you turn 65.

If a parent or sibling had CAD, especially at a younger age55 for your dad or your brother, 65 for your mom or sisteryour risk may be more than double that of people without a family history of heart disease, according to a 2019 study in the Journal of the American Heart Association. This can be due to lifestyle factors your family shared, such as smoking or a lack of exercise. Or it could be genetic.

For example, some people inherit a gene mutation that makes it likelier they will have high cholesterol, a contributor to CAD. Most often, this is caused by a mutation in the LDLR gene, which helps control the production of LDL (so-called bad cholesterol), which well get into shortly.

Men are more likely to develop CAD starting at an earlier age than women. For men, the risk tends to begin rising at about age 45. Womens risk starts to climb about 10 years later, at age 55. Experts believe this is because the hormone estrogen, which women have in greater amounts before menopause, provides some protection against CAD.

While you cant do anything to change the above, theres plenty you can do to change the risk factors below. Want some additional motivation? Improving a single risk factor often improves or even eliminates others.

Being sedentary, a.k.a. couch potato syndrome, contributes to many CAD risk factors, including HBP, obesity, diabetes, high cholesterol levels, and high triglycerides, a type of fat found in your bloodstream thats linked to atherosclerosis. When youre physically fit, your heart works more efficiently. That can improve your blood pressure. It can also help you achieve and maintain a healthy weight, which eases the burden on your heart. Plus, exercise reduces stress hormones, such as cortisol and adrenaline, that can otherwise strain your heart. And, it helps keep your cholesterol at healthy levels. Working out is basically magic for your whole body.

Lighting up damages your blood vessels. The toxic chemicals in tobacco smoke, such as carbon monoxide, may injure the walls of your arteries, and that in turn may trigger plaque buildups. Smoking also causes your blood vessels to constrict, which raises your blood pressure. Oh, and it may also thicken your blood, increasing your risk of clots by making clot-forming platelets stickier. If exercise is magic, cigarettes are kryptonite.

Does that mean you should switch to vaping? No way! E-cigarette vapor contains many toxic chemicals linked to heart disease, according to the AHA, which recently published a report that showed how vaping may harm your blood vessels in much the same way smoking cigarettes does.

Fortunately, the benefits of being smoke-free start the moment you quit. To help kick your smoking habit, check out the AHAs smoking cessation resources.

Hypertension, a.k.a. high blood pressure (HBP), stresses your arteries, causing them to harden and thicken, which makes it more difficult for blood to flow through them. The stress from HBP can also damage the lining of your arteries, and that damage may attract plaque buildups.

Carrying too many pounds increases your chances of diabetes, a major cause of heart disease. Excess weight also makes your heart work harder. That can raise your blood pressure, which then damages the inner lining of your arteries. If this seems like a chain reaction, it's because it often is. But what's important to remember? It goes the other way, too. Losing even a modest amount of weight can lower your blood sugar and your pressure.

You know the drill here: Diets high in saturated fat (like butter or beef) or trans fat (found in processed foods like cookies, crackers, and margarine), and refined carbs (like processed breads, pizza dough, pastries, and some breakfast cereals) really aren't great for your heart. Saturated and trans fats increase your bad cholesterol and decrease your good cholesterol. Meanwhile, refined carbs boost your blood sugar levels. Over time, that elevated blood sugar can lead to type 2 diabetes, a known risk factor for heart disease.

High cholesterol means you have elevated levels of low-density lipoprotein (LDL), or bad, cholesterol and low levels of high-density lipoprotein (HDL), or good, cholesterol. LDL cholesterol circulates throughout your body and can build up on the walls of your arteries, which makes them hard and stiff. This often happens when you dont have enough HDL at the ready; this blood fat actually sweeps up the excess LDL and takes it to liver to be processed as waste.

This sleep disorder causes repeated interruptions to your breathing throughout the night and has been linked to obesity and HBP, both major risk factors for CAD. Sleep apnea impacts blood pressure by causing frequent drops in blood oxygen levels during moments of interrupted breathingforcing your heart to work harder.

Your immune response can be triggered by plaque buildups in your arteries, leading to inflammation. Over time, low levels of chronic inflammation irritates your blood vessels and may make a plaque buildup more vulnerable to rupture.

Plaque buildup that leads to CAD often moves slowly, over many, many years. In fact, it can begin as early as childhood. But you wont necessarily know that you have it. Usually, symptoms of CAD dont begin until youre well into middle age or nearing retirement.

For some people, the first symptom of CAD will be a heart attack. This makes it critical to discuss your CAD risk factors with your doctor to determine the state of your heart health.

Symptoms of CAD include:

This is also known by its fancier name, angina. It occurs when your heart doesnt get enough oxygen-rich blood. You may feel pain, pressure, or a squeezing sensation in your chest. It frequently goes away when you rest.

Panting or struggling to get enough air can occur from restricted blood flow in your hearts arteries and the reduced amount of oxygen that results, often during or after physical activity.

Feeling exhausted after your normal activities or your usual exercise routine can also result from restricted blood flow and reduced oxygen-rich blood.

Pain in other parts of the body such as the neck, jaw, shoulder, and back may occur because some nerves in the heart are connected to these areas, so symptoms can be felt in these more distant places. Its not clear why this happens, but it may be due to the way your heart and brain are wired. When the brain sends out pain signals during a heart attack, those signals may activate nerves in a network in and around the heart.

The answer? Sometimes, yes. In fact, women are 50% more likely to report having a heart attack without obvious signs like chest pain, although it does remain their most common symptom, especially after age 65, when they no longer enjoy the protective effect of estrogen.

Among women, other common symptoms include:

Its thought the difference in heart attack symptoms between men and women may be a result of men having more plaque ruptureswhich occur suddenly and cause classic, chest-clutching symptomswhile women experience more plaque erosions, which happen slowly over days or even weeks, causing what are known as atypical symptoms, such as nausea, weakness, and light-headedness.

Your doctor will begin by reviewing your symptoms and taking a detailed health history, including your family history of heart disease. Youll also be asked to describe your daily habits that affect your health, such as diet and exercise. Your physical exam will include blood pressure measurements and blood tests, including cholesterol, triglycerides, blood sugar, and more.

Further testing likely will include:

This test records the electrical activity inside your heart and shows whether or not its beating normally. An EKG also reveals whether your heart is receiving an adequate amount of blood.

Your heart will be monitored via EKG while you walk on a treadmill or ride a stationary bike. This will determine whether your heart gets enough blood and oxygen during exertion. If you cant exercise, you will be given a nuclear stress test. A small amount of radioactive tracer gets injected into your bloodstream. Using special cameras, a doctor can track its movement through your heart, revealing areas that get insufficient blood flow.

This test uses sound waves to produce images of the heart that allow doctors to evaluate your hearts strength and how well it functions.

A thin tube called a catheter is inserted into a blood vessel near your groin and threaded through to your coronary arteries. A special type of ink will be injected into your arteries. The ink will show your doctor, via x-ray images, where your blockages are located. Catheterization is considered the gold standard for diagnosis. You will be awake but mildly sedated during this procedure.

A computed tomograpy (CT) scan measures the amount of calcium in your arteries. Why calcium? Its a component of the plaque buildup thats blocking your artery.

Treatment for CAD has several goals: to ease the hearts workload, to improve blood flow, and to slow or reverse plaque buildup in the arteriesall of which can help extend your life. There are a menu of treatment approaches to accomplish this, including:

What works best for you will depend on your individual health history, ability to change any unhealthy habits you might have, and what your doctor prescribes based on screening tests.

A critical part of any treatment plan, this parts largely up to you to focus on and continue over your lifetime. Medications and procedures may helpthey might even save your lifebut to be the healthiest you can be, you must do the heavy lifting.

Your goal: 150 minutes of moderate exercise, such as walking, each week. That breaks down to 30 minutes, five times a week. Before you start, ask your doctor what type of exercise program would be best for you. Often, the best way start is to put one foot in front of the other. You know: Take a walk.

Focus your food choices on fruits, vegetables, whole grains, and legumes such as beans, lean meat, and fish. Read food labels so you can avoid foods with saturated fats and/or trans fats as well as highly caloric foods loaded with sodium and/or sugar.

Your body mass index (BMI, a ratio of height to weight used to estimate body fat) should be in the normal range, between 19 and 25. Higher than that and you are overweight or, at 30 and above, obese. (Unless, that is, you're a serious gym bunny whose measurements in pure muscle defy regular BMI standards.) Start with small, achievable weight loss goals, because losing as little as five to ten pounds can pay dividends in health benefits, such as lower blood pressure.

It's true the more you smoke, the greater your health risks, but even light or part-time smokers should drop the habit. Women who are light smokers, for example, have a 500% higher risk of lung cancer than non-smokers. And light smoking may leave you with other forms of lung disease or cause a stroke, breast cancer, or cataracts, or the list goes on and on.

No one likes being stressed out. But did you know that too much stress harms your heart? It can boost your blood pressure and make you more prone to give into unhealthy temptations, like smoking and overindulging in junk food or alcohol. The AHA recommends stress management, which you can get with the help of a therapist, at a cardiac rehab program, through regular exercise, or simply by breathing deeply.

A variety of medications exist that can help reduce CAD symptoms such as chest pain as well as prevent the progression of the disease and prevent heart attacks.

Lowering blood pressure reduces your hearts workload. Beta blockers lower blood pressure by slowing your heart rate and easing the force of your hearts contractions. Calcium channel blockers work by relaxing your blood vessels. Some also will slow your heart rate, and they may be used for chest pain.

These drugs (like aspirin) help prevent the formation of dangerous blood clots, which can develop around plaque buildups.

This treatment, which includes nitroglycerin, dilates, or widens, narrowed arteries from CAD to boost blood flow to your heart, which in turn eases chest pain. Nitrates also widen the veins, which helps ease the strain on your heart.

These medications, which include common brand names like Lipitor and Crestor, are used to control cholesterol levels. This reduces plaque buildup in your arteries. Statins may also help clear existing plaque buildups. Other cholesterol-lowering drugs are available if you cant take statins.

This drug, often prescribed under the brand name Ranexa, helps ease chest pain (angina) if it persists despite the use of other therapies. It does this by improving blood flow, allowing the heart to work more efficiently.

When your arteries are severely blocked, you may require a procedure that opens them up to let a sufficient amount of blood flow to pass through. Such procedures include:

In this procedure, a surgeon takes an artery or vein from elsewhere in your bodyoften a leg, forearm, or your chestand uses it to connect your aorta to the blocked artery, rerouting blood flow.

A cardiologist threads a catheter through a blood vessel to the point of the blockage. There, a small balloon is inflated, which flattens the plaque on the wall of your artery. Then, a stent is implanted at the site to hold the artery open. This allows blood to flow more freely and prevents the collapse of the artery.

Current treatments and earlier diagnosis are helping people live better lives with CAD, but a lot of the work is up to you. Cardiac rehabilitation will help.

Cardiac rehab, which typically consists of 36 sessions over 12 weeks, offers:

The AHA recommends cardiac rehab for everyone with coronary artery diseaseeven if you havent suffered a heart attack. To participate, you will need a referral from your doctor. The AHA also suggests you initiate this discussion with your doctor. Dont wait for your physician, who may be very busy with many patients that day, to bring it upyour heart health is too important for you to remain passive. So be your own best advocate. It just may save your life. People who attend cardiac rehab after a heart attack reduce their risk of dying by more than 50% compared to those who dont attend, according to the CDC.

Worry is a strong wordso lets just say: Be proactive. CAD symptoms dont often begin until the plaque buildup has narrowed an artery by 70%. However, plaque can rupture, which causes heart attacks, and this commonly occurs when a blockage is only a 50% obstruction. If you have any CAD risk factors, discuss them with your doctor.

While chest pain and shortness of breath are hard to ignore, it can be difficult to decide whats important if you have vague symptoms like nausea. In most cases, after all, nausea is NOT due to CAD. But if you have known risk factors for heart disease and are worried that you may be having a heart attack, call 911 immediately.

Lifestyle modification is the cornerstone therapy for halting the progression of CAD. The most beneficial? Exercise. Regular workouts get your heart pumping; reduce inflammation, cholesterol and blood pressure; improve the health of your blood vessels; lower stress; and make you feeland even lookgood, too.

If you have heart disease, youre at higher risk of depression. That makes addressing mental health one of the most important things you can do for CAD. If youre not doing well emotionally, youll be less likely to take your medications as directed, and you might find it harder to stick to a healthy diet and a regular exercise routine. Talk to your doctor if you feel anxious or depressed.

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What is Coronary Artery Disease (CAD)? And Other Questions - HealthCentral.com

Global Bone Marrow Transplant Rejection Treatment Market Growth Projection

The new report on the global Bone Marrow Transplant Rejection Treatment market is an extensive study on the overall prospects of the Bone Marrow Transplant Rejection Treatment market over the assessment period. Further, the report provides a thorough understanding of the key dynamics of the Bone Marrow Transplant Rejection Treatment market including the current trends, opportunities, drivers, and restraints. The report introspects the micro and macro-economic factors that are expected to nurture the growth of the Bone Marrow Transplant Rejection Treatment market in the upcoming years and the impact of the COVID-19 pandemic on the Bone Marrow Transplant Rejection Treatment . In addition, the report offers valuable insights pertaining to the supply chain challenges market players are likely to face in the upcoming months and solutions to tackle the same.

The report suggests that the global Bone Marrow Transplant Rejection Treatment market is projected to reach a value of ~US$XX by the end of 2029 and grow at a CAGR of ~XX% through the forecast period (2019-2029). The key indicators such as the year-on-year (Y-o-Y) growth and CAGR growth of the Bone Marrow Transplant Rejection Treatment market are discussed in detail in the presented report. This data is likely to provide readers an understanding of qualitative and quantitative growth prospects of the Bone Marrow Transplant Rejection Treatment market over the considered assessment period.

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The following manufacturers are covered:Bellicum Pharmaceuticals, Inc.Bio-Cancer Treatment International LimitedBiogen IncBoryung Pharmaceutical Co., Ltd.Bristol-Myers Squibb CompanyCantex Pharmaceuticals, Inc.Capricor Therapeutics, Inc.Cell Source, Inc.Cell2B S.A.CellECT Bio, Inc.Cleveland BioLabs, Inc.Compugen Ltd.Cynata Therapeutics LimitedCytodyn Inc.Dompe Farmaceutici S.p.A.Dr. Falk Pharma GmbHEscape Therapeutics, Inc.F. Hoffmann-La Roche Ltd.Fate Therapeutics, Inc.Generon (Shanghai) Corporation Ltd.

Segment by RegionsNorth AmericaEuropeChinaJapanSoutheast AsiaIndia

Segment by TypeAzathioprineAdrenocorticotropic HormoneCyclophosphamideCyclosporine AOthers

Segment by ApplicationHospitalClinicOthers

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Global trade impact of the Coronavirus Bone Marrow Transplant Rejection Treatment Market Worldwide Growth Survey by 2028 - Cole of Duty

An Italian teenager may be the first known case of a painful thyroid infection caused by the new coronavirus, doctors report.

A research team from Pisa, in northern Italy, said the 18-year-old woman's thyroid became sore and enlarged a few weeks after testing positive for the SARS-CoV-2 virus in late February. The condition, called thyroiditis, cleared up completely within a week after she was treated with the steroid prednisone.

Still, the doctors believe that "physicians should be alerted about the possibility of this additional clinical manifestation" tied to the new coronavirus, study leader Dr Francesco Latrofa, an endocrinologist at the University Hospital of Pisa, said in a news release from the Endocrine Society. He and his colleagues published the findings on 21 May in The Journal of Clinical Endocrinology & Metabolism.

"Covid-19 continues to show us many surprises," said thyroid expert Dr David Hiltzik, director of head and neck surgery at Staten Island University Hospital in New York City. "It has been shown to manifest in so many different organ systems throughout the body, so it is not surprising that the thyroid joins the many other areas that have been affected by the disease.

Heart palpitations and neck pain

"Thankfully, thyroiditis can easily be treated and should not be of great concern," added Hiltzik, who wasn't involved in the new research. "That being said, if a patient had the virus and presents with new neck pain they should get that evaluated."

In the Italian woman's case, she first got a nasal swab test for the new coronavirus on 28 February because her father had been hospitalised earlier with Covid-19. The test turned up positive, but she experienced only mild, transient respiratory symptoms at first.

However, by 17 March she revisited the Pisa clinic with fever, heart palpitations and neck pain. The neck pain got worse and her thyroid gland was painful and enlarged, the doctors said.

Tests confirmed thyroiditis. The patient was given prednisone, which relieved the neck pain and fever within two days. Any other remaining symptoms subsided within a week.

Post-viral thyroiditis

Latrofa and his group noted that thyroiditis has been seen with a myriad of infections, including mumps, Epstein-Barr, hepatitis E and HIV, so its appearance with SARS-CoV-2 isn't completely surprising. But to their knowledge, this is the first such case tied to the new coronavirus.

Dr Minisha Sood is an endocrinologist at Lenox Hill Hospital in New York City. Reading over the findings from Italy, she said it was "a classic presentation of post-viral thyroiditis, which is characterised by the onset of neck pain, fever and high thyroid hormone levels".

Sood said because of the intensity of neck pain the woman was experiencing, her doctors prescribed prednisone. However, in milder cases, a nonsteroidal anti-inflammatory pain reliever is often prescribed first, with a steroid prescribed later if needed.

In any case, "as an increasing number of post-viral symptoms are being attributed to Covid-19 or complications of Covid-19 such as thrombotic [clotting] events, the potential of subacute thyroiditis should not be overlooked," Sood said.

Image credit: Getty Images

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Coronavirus can infect and inflame the thyroid - Health24

I have always been tempted to write a prescription that reads Go out and play just to see how the parent responds.

Turns out, there is no better time than this nearly three months into the social distancing, no public gatherings and shelter-at-home requirements to prevent the spread of COVID-19 to follow that exact recommendation.

As a pediatrician in Kenner Army Health Clinic, I have observed how this situation has not been ideal for people in general. They have been affected physically, emotionally, socially and economically. For children, there is another vulnerable plane, developmentally.

Lately, I have encountered an unusual number of TeleHealth concerns related to emotional, behavioral and developmental regression in youngsters. It is troubling to imagine the coronavirus mutating into a dreadful boogeyman that inflicts children with these mental health issues.

Its simple to beat the monster, though, with play which is defined in a 2018 American Academy of Pediatrics article as an activity that is intrinsically motivated, and entails active engagement and results in joyful discovery.It is not scripted play therapy, but genuine family activity that brings forth positive emotions while promoting child development and growth.

The Pediatric Journal magazine article further reads, When play and safe, stable, nurturing relationships are missing in a childs life, toxic stress can disrupt the development of executive function and the learning of prosocial behavior. In the presence of childhood adversity, play becomes even more important.

The article points out that age-appropriate play with parents and peers is a singular opportunity to promote the social-emotional, cognitive, language and self-regulation skills that build executive function and a prosocial brain which children need to thrive.

Research among preschoolers on the first day of school showed a twofold decrease in anxiety in medical terms, a reduction in the stress hormone salivary cortisol when randomly assigned to play intervention compared to listening to a teacher reading a story.

Laboratory scientists also have simulated the role of roughand-tumble play and learned that it can buffer symptoms of anxiety in animals that similarly showed a reduction in stress hormone that could be prolonged by the length and intensity of the activity level. The researchers observed increased brain competency in the subjects, witnessing the ability to solve mazes after two hours compared to the play-deprived group.

With the ongoing challenges of the pandemic, caregivers may want to invest in more meaningful play time with children, and while doing so, may even find themselves unexpectedly rewarded. By recreating their cherished childhood activities or sharing a favorite game with youngsters, some grown-ups may benefit from this renewed joy through a childs view. This benefit also is supported by a research.

Organized daily playtime at home during this pandemic may seem tiring to already stressed-out parents, but the rewards are worth the investment. Spontaneity is welcomed in this area and may surprisingly bring more fun. Encouraging children to plan the activity is a good tool for self-growth. Parents are not asked to be activity directors. Play should not be a dreaded chore and should never add more stress. And like any medicine, it should not be overdosed responsible adults have to work and rest, and children need downtimes as well.

With studies consistently showing the superior benefits of real-time social playing among young children, some limited age-appropriate screen time with parents co-watching or co-playing can be an occasional alternative. Play needs adult supervision because it can have a dark side when children are allowed to do as they please, leading to disagreements and even bullying. Homes should always be safe and nurturing a play hideout from the coronavirus boogeyman.

Playing is important for everyones well-being, and especially for the development of a young healthy child. While peer-to-peer play is almost impossible due to social distancing, families must strive together, more than ever, to create nurturing physical connections through playtime now; because playing is a medical necessity for children to thrive.

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Play: A joyful medicine - Public Affairs Office of Headquarters, US Army Combined Arms Support Command and Fort Lee

HEALTH REASONS. KC Concepcion says she been diagnosed with polycystic ovary syndrome or PCOS, which has prevented her from accepting showbiz projects. Screenshot from Instagram/@itskcconcepcion

MANILA, Philippines Actress KC Concepcion said she had been scaling back in accepting showbiz projects after she was diagnosed with polycystic ovary syndrome or PCOS.

In an interview with Tim Yap on his online show on Saturday, May 23, KC was asked why she has not been seen on television or movies, despite signing with Cornerstone Entertainment back in February.

"I am super, super grateful for work. But number one... I want to be super open about this because its something I also want to talk about in the future. I was diagnosed with PCOS," she said.

PCOS, according to the Mayo Clinic, "is a hormonal disorder common among women of reproductive age" which results in "infrequent or prolonged menstrual periods or excess male hormone (androgen) levels."

The condition is the reason why she gained weight, she said.

"I always wanted to be at my best, I want to be physically fit, and I want to look good, I want to get my body tight. When I look good, I feel good and thats what you serve people on screen. Its as simple as that, she said.

While she was on break, KC said that she was able to work on a lot of things, including her jewelry line Avec Moi. She is also set to revive KC's Closet to pre-loved items for charity.

KC said that she's been getting a lot of guidance with her PCOS thanks to her doctor in the US. I know a lot of women who have it. Its quite common in a way but not a lot of people talk about it. Thats something I want to talk about in depth later on in the future na because I dont think right now is the time. Wala pa ako masyadong information about it, she said.

(I still don't have much information about it.)

KC said she now ready to accept projects coming her way. Im super healthy now. Im so well. I take supplements, try to be as active as I can be."

Relationship with mom Sharon

In the same interview, Tim asked if KC has been in contact with her mom, Sharon Cuneta, and her family. KC is currently living by herself in her apartment .

KC said they've been checking up on each and that they've been sending each other food.

"That's our way of expressing our love is through gifts. I think my mom and I have the same love language, where we like to give each other gifts. I miss her, I love her so much. I think she is an amazing mom. At the end of the day, lahat ng nangyayari sa amin should stay in the family and just like any family, no one is perfect, she said.

(At the end of the day, whatever is happening in our family should just stay within the family and just like any family, no is perfect.)

Back in January, Sharon wrote a long post on social media, asking KC to come back to the family. The actress was not present during some of their holiday gatherings and Sharon's birthday celebration on ASAP.

Sharon told the media that the post was a case of a "mother missing her daughter."

The two have since ironed things out, with Sharon promoting KC's YouTube account in March.

KC said that like any other family, their relationship has not been perfect.

I dont really like talking about problems in public but people love us and have really welcomed us in their lives. I want to thank everyone that is there to support my relationship with my mom. Every day, you just want everything to be nice and light and happy, " she said.

"If there was time lost before, I think the most important thing is to both embrace each others imperfections and forgive and be loving towards each other. Thats the best we can do, she said. Rappler.com

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KC Concepcion says PCOS prevented her from accepting projects - Rappler

Amy Sapien had prepared for her April 13 surgery as best she could. She dyed her long blond hair a bright pink. She got a tattoo on her right calf of what she jokingly calls her spirit animal Dory, the blue fish from Finding Nemo, whose answer to lifes challenges is to say, over and over, Just keep swimming. Still, she was overwhelmed by dread early that morning as she kissed her husband, Callen, goodbye outside the Moffitt Cancer Center in Tampa, Fla., and walked alone through the bright, empty lobby. Her hands shook as she stepped onto the elevator and pressed the button with her elbow.

Her mind was a jumble. Everyone seemed so eerily expressionless from behind their paper masks that Sapien wondered for a moment whether shed walked onto the set of an alien abduction movie. She had been imagining for weeks what it would be like to leave the hospital without her left breast. Now her mind turned to an even more urgent fear: What if she became infected with the coronavirus during her short stay?

Sapien tried to replace her anxious thoughts with fighting ones. The 40-year-old hospital social worker made Tom Pettys lyrics her mantra: You can stand me up at the gates of hell, she sang to herself as she felt her consciousness give way in the operating room. But I wont back down.

When she came to three hours later, she pushed aside her worries about the treatment and procedures she still faced, nibbled on Saltines, and sipped ginger ale to stave off the nausea she felt from anesthesia. Then she reached for her phone, and recorded separate video messages for her two young boys.

Her blue eyes glazed thick from painkillers, she addressed her 3-year-old son, Corben. Smiling reassuringly, she told him to continue his toilet training with his grandmother, and that shed be home soon. Then she spoke to 7-year-old Landen. Hey. Im OK. Im out of surgery, she said in a near-whisper. With her bandage peeking from her pink surgical robe, she told him that shed be home the next day, and that they would soon be able to watch movies together from the bedroom recliner. I love you, I dont want you to worry about me, Landen, she said. OK? Im doing really good. Bye, honey.

Then she tapped send. Landen watched the video from his own hospital room across town, where he was being treated for leukemia.

Amy and Landen, two generations fighting cancer, are united by something else: They are going through the most frightening and painful moments of their lives without the family warmth and support that was standard practice at the nations medical centers until Covid-19. The pandemics broad impact on cancer care in the U.S. is well-known: non-essential surgeries, biopsies, and scans delayed, and clinical trials disrupted. But its in stories like the Sapien familys that one sees the depth of the harm its causing.

Amy was able to schedule the mastectomy right away only because her cancer was spreading, but she couldnt have her second breast removed at the same time since it was deemed elective. Instead shell have to undergo general anesthesia, surgery, and painful rehab again. While her husband was allowed in the waiting room during her first worrisome mammogram and ultrasound in early March, Amy had to go alone for her biopsy and the MRI that confirmed the diagnosis. Then she went by herself to her surgery, and recovered in isolation.

I didnt see anyone I knew for 36 hours after having a part of my body amputated, she said. Worse, though, was her inability to be with Landen as he lay tethered to a machine delivering a platelet transfusion.

While both parents, and sometimes his grandparents, had been able to reassure him through previous chemotherapy treatments, this time only his father could be present.

Theirs is an experience shared by cancer patients across the country, as Covid-19 separates them from loved ones and family at their time of greatest need.

In the exact moment where we could have reached out for everything our support system could offer, Amy said, we were forced to retract completely into ourselves.

It was last June, a few weeks before Landens seventh birthday, that his grandmother Sandra Sapien noticed a swollen gland on his slender neck. The family had just moved from a nearby town and had not yet met their new doctors, so Amy took Landen to a walk-in clinic to rule out strep. The test was negative, but the doctor suggested following up with a pediatrician and asked if there was a family history of leukemia. No, Amy said, alarmed. None at all.

Days later, at an appointment with Landens new pediatrician, Amy mentioned what the urgent-care doctor had said and asked if he could run some blood tests. Its never cancer, he told her. He diagnosed Landen with tonsillitis, and prescribed antibiotics. Landen seemed fine at his birthday party, and wolfed down pizza and the massive chocolate Minecraft cake his grandmother had made.

The morning of June 29, the family drove to a pet store to pick out a fish for Corben. As he deliberated among the bright blue and red beta fish, Landen turned gray and collapsed. Thinking that hed had a bad reaction to the antibiotics, Callen rushed him to the hospital.

In just a few hours, the couple went from worrying about whether rain would spoil that evenings fireworks to confronting every parents nightmare. After doctors ran a battery of tests, the Sapiens learned that their son was one of 350 to 525 U.S. children diagnosed with a rare form of leukemia each year. Overall, 3,500, or 4.7 out of 100,000, are diagnosed annually with childhood blood cancers.

Leukemia? Amy recalls asking, incredulous. My brain wasnt even linking up what the word was.

As a young woman, Amy had struggled with anxiety, but finally everything had fallen into place. She and Callen, 36, a strategist at a business software company, had solid, steady careers. Together since their first meeting at a college-town coffee shop 17 years ago, they had just purchased their dream home. Id finally convinced myself there were no monsters under my bed, she said.

Now the doctors were hospitalizing their son, and had begun a 3 1/2 year regimen of in- and outpatient chemotherapy treatments that during some stretches required daily infusions.

Callens mother and stepfather, colleagues, and friends rushed to help, providing lunches, dinners, even breakfasts, so the family could focus on Landen and managing his hospital schedule. Amys co-workers donated sick leave.

The couple tried to make life as normal as possible for Corben; both continued working, and resolved never to show their fear to their son. Nobody ever got a trophy for crying on the floor for three years, Amy said.

Early this winter, news of the pandemic began to percolate. Because Landens treatments impaired his immune system, he was at risk for opportunistic infections. The family had initiated a series of precautions: limiting visitors; carrying hand sanitizer; washing every item that came into their house. We were acting as if Covid existed before Covid existed, Callen said. We were already being hypervigilant.

One evening in mid-February, the whole family was gathered on the couples bed watching Ninjago. Amy was leaning against Callens arm, which had fallen asleep. When she wriggled away to release it, her left breast grazed his hand. In that split-second touch, he felt something unusual and hard. Whats that? he asked. Amy padded her breast with her fingertips, immediately detecting a small mass.

Her mother had had breast cancer, and her grandmother had died of the disease. But they had drank and smoked, lifestyle behaviors that increased their risk. Amy had had a baseline mammogram at 33, and had tested negative for the BRCA genes that dramatically increase the risk of breast cancer. I thought I had an insurance policy against having to go through this, she said.

When she turned 40 in October, her doctor had recommended that she get a second mammogram. But she had told herself she would schedule it until after Landen had completed his first year of treatment.

Now she feared the worst. Landens diagnosis had been improbable. Could the universe betray them twice? Im scared, she told Callen.

Landen, hypersensitive to any health news, looked up. Why?

Amy reigned herself in. I couldnt cry in front of him after watching him be poked and prodded hundreds of times and never complaining. Its not fair to expect a 7-year-old to do what I cant.

I couldnt cry in front of him after watching him be poked and prodded hundreds of times and never complaining.

She was sitting at her work desk when a nurse practitioner called her cellphone with the biopsy results: She had invasive lobular cancer. Amy tried to write down the diagnosis on the back of an envelope. The words went into my ears, but they just werent registering, she recalled. How do you spell that? she kept asking. She hung up and burst into tears. Its not fair, she said to her office mate, who was trying to console her. Were good people. It was supposed to be benign.

In those early weeks of the coronavirus, hospitals were just putting in place social distancing rules to protect patients from infection. Family members were prohibited or sharply limited from joining cancer patients as they go from diagnosis to surgery, from chemotherapy to recovery.

Suddenly, the Sapiens could no longer turn to their community for help either. Their kitchen, in disrepair after a massive leak, had only a working hot plate, but they couldnt accept meals. Amy, who has a well of close friends, couldnt see them on weekend lunch dates.

Cancer remains the second-leading cause of death in the U.S., and 1.8 million people are diagnosed annually. Many end up with plans of treatment that last for months, if not years, that require regular surveillance and lifesaving but immune-suppressing drugs.

In her job, Amy has worked with a series of vulnerable populations, from the homeless to veterans to the elderly. As she lurched alone from procedure to procedure at Moffitt, she of course understood that barring patients partners reduced the chance of infections by half. But she also knew that family members play an important role in making decisions about treatment. Its so hard to absorb what youre hearing when youre the patient, she said. That second pair of ears is so important in cancer treatment.

Meanwhile, St. Josephs Childrens Hospital, where Landen was being treated, issued similar restrictions. In the past, we allowed parents, grandparents, even siblings to accompany patients during treatment, said Don Eslin, Landens pediatric hematology oncologist. Now they can only have one parent.

As recently as February, he said, it was common for families whose children were being treated for blood cancers to share stories and encouragement in cafeterias and the waiting room.

Now that support is reduced to a wave from behind a mask down the hallway, Eslin said.

Doctors, too, saw their routines upended in unsettling ways. Eslin must sometimes deliver bad news by phone, something he has always striven to avoid. This is adding complexities to cancer care in a way we never imagined, he said.

Catherine Lee, Amys surgeon, feels most the loss of connection with patients. Since the third week of March, she has only been able to make eye contact with her patients at one of the most terrifying moments of their lives.

A breast cancer diagnosis is so intimate, Lee said. We always want our patients to feel that we are giving as much as we can to them in terms of support and compassion, and to reassure them that were doing as much as we can for them.

From behind her mask, she can only offer supportive words. They cant see my smile. I cant shake their hands, and I certainly cant give them a hug, she said.

In their brief meeting, Lee and Amy discussed Landens situation, and how Amy needed to be back on her feet as soon as possible.

As Lee reflected on the case during a FaceTime call, she paused for a moment: You know something? I dont even know what Amy Sapien looks like.

For the past seven weeks, she said, about the only thing I see of my patients is their breasts.

Amy is recuperating, working from home to help veterans navigate the Covid-19 crisis. She is never far from her sons, and tells them every day how lucky she feels to be their mother. Landen is now in maintenance therapy, and his doctors have replaced his grueling chemo infusions with an oral drug. Some days, his second grade teacher drops by, and they shout to each other through a closed window.

Earlier this month, she got the news that she wont need chemotherapy, but will be on hormone suppression treatments for at least the next decade, and will go into rapid menopause. It is highly likely that she will need a hysterectomy.

Still, she tries to focus on what she can control. She oversees Landens home schooling, which he does by Zoom with his teacher. She watches the boys as they make up imaginary games with their Duplos, and swim in the backyard pool when Landen is well enough. The family just got a new puppy, a brown Bernedoodle named River. The Sapiens had promised a party and a puppy as a way to mark the end of Landens infusions, and what they hoped would be the resumption of a more ordinary life. The puppy adds chaos but also normalcy.

Although Amy and Callen have tried to shield the children from the news, the pandemic is nonetheless a constant backdrop. Sometimes Landen wonders aloud about whether the virus could kill him or everyone in the family. And he worries about his mother, telling her recently that he hoped she wouldnt have to get an infusion port like his. Amy tries to reassure him.

I tell Landen being brave isnt not being scared, she said. Its being scared and doing it anyway.

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Covid-19 isolates patients from loved ones at time of greatest need - STAT

The Blood Testing Market report includes overview, which interprets value chain structure, industrial environment, regional analysis, applications, market size, and forecast. This is a latest report, covering the current COVID-19 impact on the market. The pandemic of Coronavirus (COVID-19) has affected every aspect of life globally. This has brought along several changes in market conditions. The rapidly changing market scenario and initial and future assessment of the impact is covered in the report. The report provides an overall analysis of the market based on types, applications, regions, and for the forecast period from 2020 to 2026. It also offers investment opportunities and probable threats in the market based on an intelligent analysis.

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Key List Market Participants in the Market:Abbott LaboratoriesBio-Rad LaboratoriesF. Hoffmann La RocheSiemens Healthineers

By Types:GlucoseLipidBUNA1CCRPVitamin DALTASTThyroid Stimulating Hormone

By Applications:HospitalsClinic and Diagnostic CentersOthers

Scope of the Blood Testing Market Report:

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By Regions:North America (The USA, Canada, and Mexico)Europe (Germany, France, the UK, and Rest of Europe)Asia Pacific (China, Japan, India, and Rest of Asia Pacific)Latin America (Brazil and Rest of Latin America.)Middle East &Africa (Saudi Arabia, the UAE, South Africa, and Rest of Middle East & Africa).

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Blood Testing Market Historic Data (2015-2019):

Blood Testing Market Forecast (2020-2026):

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Blood Testing Market 2020 Industry Size, Trends, Global Growth, Insights And Forecast Research Report... - Azizsalon News

Due to the pandemic, we have included a special section on the Impact of COVID 19 on the Endometriosis TherapiesMarket which would mention How the Covid-19 is Affecting the Industry, Market Trends and Potential Opportunities in the COVID-19 Landscape, Key Regions and Proposal for Endometriosis Therapies Market Players to battle Covid-19 Impact.

The Endometriosis TherapiesMarket report is one of the most comprehensive and important data about business strategies, qualitative and quantitative analysis of Global Market. It offers detailed research and analysis of key aspects of the Endometriosis Therapies market. The market analysts authoring this report have provided in-depth information on leading growth drivers, restraints, challenges, trends, and opportunities to offer a complete analysis of the Endometriosis Therapies market.

Top Leading players covered in the Endometriosis Therapies market report: AbbVie, EliLilly, AstraZeneca, Bayer, AstellasPharma, MeditrinaPharmaceuticals, Pfizer, NeurocrineBiosciences, TakedaPharmaceutical and More

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The report offers clear guidelines for players to cement a position of strength in the global Endometriosis Therapies market. It prepares them to face future challenges and take advantage of lucrative opportunities by providing a broad analysis of market conditions. the global Endometriosis Therapies market will showcase a steadyCAGR in the forecast year 2020 to 2026.

Market Segment by Type covers:HormonalContraceptivesGonadotropin-releasingHormone(Gn-RH)AgonistsProgestinTherapyAromataseInhibitors

Market Segment by Application covers:HospitalClinicOther

Our Complimentary Sample Endometriosis Therapies market Report Accommodate a Brief Introduction of the research report, TOC, List of Tables and Figures, Competitive Landscape and Geographic Segmentation, Innovation and Future Developments Based on Research Methodology.

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Regions Covered in the Global Endometriosis Therapies Market: The Middle East and Africa (GCC Countries and Egypt) North America (the United States, Mexico, and Canada) South America (Brazil etc.) Europe (Turkey, Germany, Russia UK, Italy, France, etc.) Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)

Years Considered to Estimate the Endometriosis Therapies Market Size:History Year: 2015-2019Base Year: 2019Estimated Year: 2020Forecast Year: 2020-2026

Highlights of the Report: Accurate market size and CAGR forecasts for the period 2019-2026 Identification and in-depth assessment of growth opportunities in key segments and regions Detailed company profiling of top players of the global Endometriosis Therapies market Exhaustive research on innovation and other trends of the global Endometriosis Therapies market Reliable industry value chain and supply chain analysis Comprehensive analysis of important growth drivers, restraints, challenges, and growth prospects

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Endometriosis Therapies Market Global Industry Outlook, Share, Growth Analysis, Trends and top manufacture like AbbVie, Eli Lilly, AstraZeneca,...

Doctors warn that taking high doses of Vitamin D has little or no effect on COVID-19, and they urge against taking more of the supplement than is recommended since it can have adverse health effects.

This update comes in the wake of people pounding down the D supplementsas a prophylactic measure, after learning that many patients with the worst symptoms and outcomesafter being diagnosed with COVID-19, have also been vitamin D deficient.

Countries, where COVID-19 cases have resulted in the highest death rates, are also those where more of the population has D deficiencies. Researchers across the globe have found thatthe sickest patients often have the lowest levels of vitamin D.These facts have led individuals who are not sick to start taking large doses of vitamin D.

There is a connection between vitamin D and respiratory illness, but that does not mean that overdosing is a healthy move. Expertsdo say that healthy blood levels ofvitamin Dmay give some protection against the worst symptoms if you do contractCOVID-19. One possible advantageis that vitamin D can help preventthe body from experiencing the so-called "cytokine storm," when the body'simmune systemoverreacts and attacks itsown cells and tissues, much like a histamine response to an allergen. But too much D is not beneficial.

In anew warning by doctors in the UK, researchers at Birmingham Universityare warning people to not overdose themselves with D to gain any potential benefits or edge against the virus. According to The Independent,a steady stream of patients are showing up at hospitalsin theUKhaving takentoxicdoses ofvitamin Dinsupplementsthey bought online. The pills that are poisoning them contain up to 2,250 times the recommended daily dose of D (which is 600 IU according to the Mayo Clinic) and this toxic level of D is putting patients at risk ofheartandkidneyproblems, according to theNHSlab, which said it sees two to three overdose cases every week.

Scientists from the UK, Europe and the US, including experts from the University of Birmingham, have published aconsensus paper warning against taking high doses of vitamin D supplementation.

According to the study,new research shows high levels of vitamin D provides little or no benefit in preventing or treating Covid-19. The study'sauthors advise that the population adhere to Public Health England guidance on supplementation.

Following unverified reports that high doses of vitamin D (higher than 4000IU/d) could reduce the risk of contracting COVID-19 and be used to successfully treat the virus, the new report published in the journal BMJ, Nutrition, Prevention and Health, investigated the current scientific evidence base on the vitamin and its use in treating infections.

Vitamin D is a hormone produced in the skin during exposure to sunlight and helps regulate the amount of calcium and phosphate in the body, which are needed to keep bones, teeth and muscles healthy.

Most of our vitamin D comes from exposure to sunlight, however for many people, particularly those who are self-isolating with limited access to sunlight during the current pandemic, getting enough vitamin D may be a real challenge. Supplementing with vitamin D ... should be done under the current UK guidance," saidProfessor Carolyn Greig, a co-author of the paper, also from the University of Birmingham.

Professor Judy Buttriss, Director General British Nutrition Foundation and a co-author of theresearch said: In line with the latest... guidance on vitamin D, we recommend that people consider taking a vitamin D supplement of 10 micrograms a day during the winter months (from October to March), and all year round if their time outside is limited.

Although there is some evidence that low vitamin D is associated with acute respiratory tract infections, there is currently insufficient evidence for vitamin D as a treatment for COVID-19 and over-supplementing must be avoided as it could be harmful.

Examining previous studies in this field, the scientists found no evidence of a link between high dose supplementation of vitamin D in helping to prevent or successfully treat Covid-19 and cautioned against over-supplementation of the vitamin, without medical supervision, due to health risks. Scientists concluded that assertions about the benefit of the vitamin in treating the virus are not currently supported by adequate human studies and are based on findings from studies that did not specifically examine this area.

Claims of a link between vitamin D levels and respiratory tract infections were also examined by scientists. Previous studies in this area have found that lower vitamin D status is associated with acute respiratory tract infections however limitations of the findings of these studies were identified. Findings from the majority of studies were based on data gathered from population groups in developing countries and cannot be extrapolated to populations from more developed countries due to external factors. Scientists believe that there is currently no firm link between vitamin D intake and resistance to respiratory tract infections.

Vitamin D toxicity, also called hypervitaminosis D, is a rare but potentially serious condition that occurs when you have excessive amounts of vitamin D in your body.

Vitamin D toxicity is usually caused by taking supplements not diet or sun exposure. Your body regulates the amount of vitamin D produced by sun exposure, and even fortified foods don't containenough vitamin D to worry about.

Too much D can lead to a buildup of calcium in your blood (hypercalcemia), which can cause nausea and vomiting, weakness, and frequent urination. Vitamin D toxicity can also leadto bone pain and kidney stones.

Treatment includes stopping vitamin D intake and restricting your calcium intake. Your doctor might also prescribe intravenous fluids and corticosteroids or bisphosphonates.

Doctors warn against taking anything more thanthe U.S. Recommended Dietary Allowance of 600IUof vitamin D per day.

An adequate level of vitamin D in the body is crucial to our overall health, too little can lead to rickets or the development of osteoporosis but too much can lead to an increase in calcium levels in the blood which could be particularly harmful,Professor Sue Lanham-New, Head of the Department of Nutritional Sciences at the University of Surrey and lead author of the study, said.

Levels of the vitamin in the body can also be supplemented through a nutritionally balanced diet including foods that provide the vitamin, such as fortified foods such as breakfast cereals, and safe sunlight exposure to boost vitamin D status.

Most. people can get enough vitamin D with about ten to 15 minutes of direct sunlight a day.

See the article here:
Doctors: Taking High Doses of Vitamin D Has No Effect on COVID-19 - The Beet

arcognizance.com has added latest research report on Global Osteoporosis Treatment Market, this report helps to analyze top manufacturers, regions, revenue, price, and also covers Industry sales channel, distributors, traders, dealers, research findings, conclusion, appendix and data source.

With the slowdown in world economic growth, the Osteoporosis Treatment industry has also suffered a certain impact, but still maintained a relatively optimistic growth, the past four years, Osteoporosis Treatment market size to maintain the average annual growth rate of 15 from XXX million $ in 2014 to XXX million $ in 2019, Report analysts believe that in the next few years, Osteoporosis Treatment market size will be further expanded, we expect that by 2024, The market size of the Osteoporosis Treatment will reach XXX million $.

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This Report covers the manufacturers data, including: shipment, price, revenue, gross profit, interview record, business distribution etc., these data help the consumer know about the competitors better. This report also covers all the regions and countries of the world, which shows a regional development status, including market size, volume and value, as well as price data.

Besides, the report also covers segment data, including: type segment, industry segment, channel segment etc. cover different segment market size, both volume and value. Also cover different industries clients information, which is very important for the manufacturers.

Section 1: Definition

Section (2 3): Manufacturer DetailAllergan PlcAmgen, Inc.Actavis Plc.Eli Lilly and CompanyF. Hoffmann La Roche Ltd.GlaxoSmithKline Pharmaceutical Ltd.Merck & Co AGNovartis AGNovo Nordisk A/SPfizer, Inc.Teva Pharmaceuticals Industries Ltd.

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Section 4: Region SegmentationNorth America Country (United States, Canada)South AmericaAsia Country (China, Japan, India, Korea)Europe Country (Germany, UK, France, Italy)Other Country (Middle East, Africa, GCC)

Section (5 6 7):Product Type SegmentationBisphosphonatesParathyroid Hormone TherapyCalcitoninSelective Estrogen Inhibitors Modulator (SERM)

Industry SegmentationHospitalsClinic

Channel (Direct Sales, Distributor) Segmentation

Section 8: Trend (2019-2024)

Section 9: Product Type Detail

Section 10: Downstream Consumer

Section 11: Cost Structure

Section 12: Conclusion

Buy The Report @ https://www.arcognizance.com/purchase/878965

Table of Content

Chapter One: Osteoporosis Treatment Product Definition

Chapter Two: Global Osteoporosis Treatment Market Manufacturer Share and Market Overview 2.1 Global Manufacturer Osteoporosis Treatment Shipments2.2 Global Manufacturer Osteoporosis Treatment Business Revenue2.3 Global Osteoporosis Treatment Market Overview

Chapter Three: Manufacturer Osteoporosis Treatment Business Introduction

Chapter Four: Global Osteoporosis Treatment Market Segmentation (Region Level)

Chapter Five: Global Osteoporosis Treatment Market Segmentation (Product Type Level)

Chapter Six: Global Osteoporosis Treatment Market Segmentation (Industry Level)

Chapter Seven: Global Osteoporosis Treatment Market Segmentation (Channel Level)

Chapter Eight: Osteoporosis Treatment Market Forecast 2019-2024

Chapter Nine: Osteoporosis Treatment Segmentation Product Type

Chapter Ten: Osteoporosis Treatment Segmentation Industry

Chart and FigureFigure Osteoporosis Treatment Product Picture from Allergan PlcChart 2014-2019 Global Manufacturer Osteoporosis Treatment Shipments (Units)Chart 2014-2019 Global Manufacturer Osteoporosis Treatment Shipments ShareChart 2014-2019 Global Manufacturer Osteoporosis Treatment Business Revenue (Million USD)Chart 2014-2019 Global Manufacturer Osteoporosis Treatment Business Revenue ShareChart Allergan Plc Osteoporosis Treatment Shipments, Price, Revenue and Gross profit 2014-2019Chart Allergan Plc Osteoporosis Treatment Business DistributionChart Allergan Plc Interview Record (Partly)Figure Allergan Plc Osteoporosis Treatment Product PictureChart Allergan Plc Osteoporosis Treatment Business ProfileTable Allergan Plc Osteoporosis Treatment Product SpecificationChart Amgen, Inc. Osteoporosis Treatment Shipments, Price, Revenue and Gross profit 2014-2019Chart Amgen, Inc. Osteoporosis Treatment Business DistributionChart Amgen, Inc. Interview Record (Partly)Figure Amgen, Inc. Osteoporosis Treatment Product PictureChart Amgen, Inc. Osteoporosis Treatment Business OverviewTable Amgen, Inc. Osteoporosis Treatment Product SpecificationChart Actavis Plc. Osteoporosis Treatment Shipments, Price, Revenue and Gross profit 2014-2019Chart Actavis Plc. Osteoporosis Treatment Business DistributionChart Actavis Plc. Interview Record (Partly)Figure Actavis Plc. Osteoporosis Treatment Product PictureChart Actavis Plc. Osteoporosis Treatment Business OverviewTable Actavis Plc. Osteoporosis Treatment Product Specification3.4 Eli Lilly and Company Osteoporosis Treatment Business Introduction continued

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Due to the ongoing COVID-19 pandemic around the world, the figures in the report study represented in the study might differ along with production capacities and other mentioned aspects. Also, note that there is a possibility of a cooldown period after the pandemic that the data might differ as the world economy aims to catch on.

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Osteoporosis Treatment Market Size, Share, 2020 Emerging-Trends, Services, Applications, Technological-Advancements, Scope, Growth-Analysis,...

Whether youre contemplating using an intrauterine device (IUD) as birth control or to curb the effects of a gynecological issue, you might wonder if the pros outweigh all the cons youve probably heard about. Heres what you need to know about IUDs, according to Ob/Gyn Ashley Brant, DO, MPH.

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services.Policy

Both types work mainly by preventing egg fertilization, but keep in mind that IUDs dont protect against sexually transmitted infections (STIs).

Despite the fact that modern versions are quite safe, IUDs still tend to get a bad rap. Dr. Brant often hears concerns from patients about migration, when the IUD moves through the uterine wall into the abdominal area. Even though it seems like almost everybody knows somebody to whom thats happened, its actually a pretty rare complication, she says. Migration can happen if the uterus is torn, usually by an instrument during IUD insertion; however, these uterine perforations only occur in 0.01 percent of cases.

Other serious complications from IUDs are rare too. Pelvic inflammatory disease (PID) occurs in just 1 percent of women within the first 20 days after insertion and in 0.5 percent in the first three to six months.

Then there are the uncommon side effects women report from the hormonal IUD like weight gain, hair loss, mood changes and acne. As of now, there isnt enough research to support or refute a definitive link between the two, Dr. Brant says. In fact, the low level of progestin released one-fifth of the amount found in combination birth control pills is tolerated well by the majority of women.

Dr. Brant asks her patients these 3 questions to help them come to a decision thats right for them:

Placing an IUD usually takes less than five minutes. To begin the insertion process, the doctor or nurse will likely feel your uterus to see which way it might be tipping. A speculum is placed, just like youd have for a Pap smear, and the cervix is washed off with soap.

You can expect to experience cramping three times, but only for a few seconds each time, says Dr. Brant.

Read more:
Do the Benefits of an IUD Outweigh the Potential Side Effects? - Health Essentials from Cleveland Clinic

When I left my job in February to focus on trying for a baby, I was full of hope. This was going to be the year Id get pregnant. Instead, Im in limbo, the possibility of becoming a mother seeming further and further away.

My husband Matthew and I have always wanted a family. Weve been together for 11 years, but because wed been teaching abroad, we waited until we moved back to the UK to start trying. In 2017, when we were settled in North Yorkshire and both in our mid-30s, I came off the Pill, but after six months nothing was happening.

My GP told me to enjoy trying to conceive and that everything was fine. But by January 2019 we were worried so had our first IVF consultation. The consultant said my FSH [follicle-stimulating hormone] results were concerning, as were the results of my AMH [anti-Mllerian hormone] test, which confirmed that I didnt have many eggs left. It was the first time we were told there was a problem. I cried all the way home.

We started IVF last May, but my body didnt create enough follicles [ovarian sacs that release eggs for fertilisation] to proceed to the egg-collection phase, so we cancelled the cycle and began again in October. It was a difficult time. The doctors upped my medication and the combination of the hormones and the desire for it to be a success made me anxious. Teaching had been my life, but suddenly it felt like it was getting in the way.

Four eggs were collected, and grew into two embryos. But by the time I was due to have them transferred into my uterus, the embryologist called with awful news: they had stopped growing. I couldnt speak, I just started crying. Matthew and I spent the rest of the day in tears that was our one free NHS cycle.

We looked for a private clinic we could afford, opting for Serum IVF in Athens, which suggested we do two lightly stimulated cycles. The cost, including flights and hotel, came to 6,000, compared to 8,000 back home for just one cycle. On 2 March, we flew to Athens. At the clinic, the doctors spotted a huge polyp in my uterus, so after my egg collection, I had it removed. I later found out that theyd only collected one egg but it was a good one.

After we returned home, we found out that our embryo had developed into a blastocyst, a more advanced embryo of very good quality. It was frozen for use at a later date. I felt calm and positive, and despite coronavirus emerging in Europe, we still thought wed be able to return for our second cycle.

But a few days later the clinic told us it was following strict new guidelines not to proceed with any transfers until further notice. I was in total despair. After two and a half years of trying and getting so close, it had all been taken away. It felt so cruel.

Read more here:
My chances of having a baby are fading away due to coronavirus - Telegraph.co.uk

The test wont tell you other factors that can affect the reproductive system like Endometriosis, Uterine Fibroids, cysts, infections or stress. But it can indicate Polycystic ovarian syndrome (PCOS).

And while the AMH test indicates the number of eggs, it will not deliver the holy grail of fertility information, the QUALITY of eggs. No, the only way to test quality is to fertilize the eggs to see if embryos form. So basically, to make a baby.

If youre not ready for that, the AMH test is at least some information.

Male fertility is so blunt: all the main bits on the outside. A new load of sperm regenerates every 64 days. One explosion in a cup and a fertility specialist has most of the picture.

But a womans fertility is an elusive and complex force of nature. She is with us for a fleeting moment and the further we move into our thirties, the more cryptic she becomes.

My first peek under the veil of my own fertility took three GPs before I was given the AMH test. My result was 11.2. Its in the lower percentile range, but normal for my age. If the results came back abnormally low, theres no question I wouldve reprioritised a baby sooner rather than later.

And if the test does identify a low egg count, its best to know at 28 rather than 35 right?

The cheap, non-invasive AMH test is not subsidised by Medicare, but IVF is. Why fund a last resort fertility procedure but not a simple test that can identify a factor to consider way before IVF is on the table?

Women should be trusted by the medical community to understand the results and not presumed to misuse or misinterpret the information. And this argument should not be used to hold the test back from women like myself just looking for a little more information.

Listen to Before the Bump, Mamamias fertility podcast. Post continues below.

For me, having a normal AMH result didnt make me prioritise a baby but it didnt make me feel less panicked either. Instead, I formed the following logic: if I had a normal egg pool for my age, it was statistically likely Id also take a normal amount of time to fall pregnant.

If I stopped using contraception methods, I anticipated three to six months at least. It could even take a year, I thought.

I wasnt actively trying and I rarely had sex because my fianc worked away. In a calendar year, there were only five months his presence would line-up with my cycle.

And yet, I fell pregnant at the first possible chance after a single night with him. Pregnant with twins.

Read more:
'There's a test to help predict fertility. But at age 34, my GP wouldn't give it to me.' - Mamamia

Thanks to hours spent working from your couch, back-to-back Zoom happy hours or just staying idle while binging a new TV show, you may find yourself moving your body less than ever during the coronavirus pandemic. Since youre not exactly overexerting yourself these days, what gives?

The short answer is this: While you may be doing less physical activity, your brain has kicked into overdrive. In other words, the exhaustion you feel is not all in your head (or technically, in this case, it actually is.)

Although you may not be commuting to work, taking your weekly spin classes or spending weekends running errands, our drastically new coronavirus lifestyles can have a bigger impact on mental health and energy levels than we might think.

Ive probably been the most unproductive Ive ever been, said Madonna Matta, a 24-year-old graduate student from Austin, Texas. Im just tired all the time. I dont know if it may be the food Im eating more carbs, less veggies or the lack of structure, but I just feel melancholy.

Generally, exercising would make me feel more energetic and lively and now the opposite has made me sluggish, Matta continued. Sometimes, it feels easier to just sleep and pretend everything were living through is fake.

For Cathrine Nelson, a 27-year-old content creator in Providence, Rhode Island, the way she feels depends on the day.

I woke up at 8 a.m. the other day and had a full day, Nelson said. Another day, I slept in until 11 a.m., listened to some podcasts and went to bed early. Ive had productive days and almost completely inactive days. I feel like I am on a slow-motion roller coaster. I dont know when I am going to hit my next peak or my next drop.

bernardbodo via Getty Images

Why stress leads to so much fatigue

While certain stressors can be helpful for focusing and problem-solving like when you need to make a deadline or when youre driving and someone swerves in front of you they are meant to be temporary. The long-term stress we may feel as a result of COVID-19 and the constant flow of news about it is not to be underestimated, and it can exact wear and tear on the body.

People face challenges that really activate the sympathetic nervous system, so its kind of classic fight or flight response, said Craig N. Sawchuk, a psychologist at the Mayo Clinic. You get the hormone release to help keep us going like adrenaline and cortisol those are good. Its really adaptive that our body can flip that switch. But its not meant to be a constant burn, either. And thats where we run into these physical problems.

According to Sawchuk, when your brain is constantly trying to adapt to uncertainty, fear and challenges like it has during this entire pandemic it takes a toll over time. Your body physically gets tired from managing all the emotional stress.

And thats where you start to see some of the energy problems starting to happen where were fatigued, Sawchuk said. We may be actually resting a lot more, sometimes unintentionally so, but its not a restorative type of rest.

Energy expenditure extends beyond just physical activity. We burn up energy processing emotion, regulating our feelings, thinking, worrying and adapting to new challenges.

We think of physical, emotional and mental energy all drawing from that same pot, so we can think of multiple systems in our lives are constantly on and in turn, are constantly draining and wearing away at us, Sawchuk said.

Granger Wootz via Getty Images

How to boost your energy, even just a little

There are ways you can boost your energy at home and control stress levels. Johna Hansen, a licensed clinical social worker in New York City, recommended trying these steps:

Its uncertain how long COVID-19 will keep us in this state of lowered physical activity and heightened stress, but Sawchuk said resilience is key as we navigate the pandemic and the aftermath.

All of us as humans are resilient we really, really are, Sawchuk said. Resilience has this almost rubberized quality to it like bouncing back. But we will bounce back. It may not necessarily be to where we were at pre-COVID-19 because experience changes us; it changes the brain.

To Sawchuk, part of building resilience is learning to accept and adapt, which looks different for everyone. In other words, no one should be beating themselves up because they failed to make a sourdough starter or join an online yoga class that day.

We have to watch out when were making unfair comparisons to people that we think are just doing great, Sawchuk said. Our goal isnt to be perfect. Our goal is to be good enough. Being good enough is being kind to ourselves. There may objectively look like theres more time available, but thats not necessarily a good thing nor does it mean that were going to be more motivated or efficient. Its about adaptation.

A HuffPost Guide To Coronavirus

Read more here:
Why You Always Feel Tired, Even If You're Moving Less Than Ever - HuffPost

The report on the Thyroid Hormone Disorder Drug market provides a birds eye view of the current proceeding within the Thyroid Hormone Disorder Drug market. Further, the report also takes into account the impact of the novel COVID-19 pandemic on the Thyroid Hormone Disorder Drug market and offers a clear assessment of the projected market fluctuations during the forecast period. The different factors that are likely to impact the overall dynamics of the Thyroid Hormone Disorder Drug market over the forecast period (2019-2029) including the current trends, growth opportunities, restraining factors, and more are discussed in detail in the market study.

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The following manufacturers are covered:Novo NordiskSanofiMerckEli LillyAstraZenecaAbbVie

Segment by RegionsNorth AmericaEuropeChinaJapanSoutheast AsiaIndia

Segment by TypeInjectionOralOthers

Segment by ApplicationHospitalClinicMedical CenterOthers

Global Thyroid Hormone Disorder Drug Market by Geography:

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Some of the Major Highlights of TOC covers in Thyroid Hormone Disorder Drug Market Report:

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Chapter 5: Company Profile

And Continue

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The impact of the coronavirus on the Thyroid Hormone Disorder Drug Market Analysis Research and Trends Report for 2020-2029 3w Market News Reports -...

By: Taylor Roar, Capital News Service

Health professionals and federal agencies have expressed concern about the mental health effects of the global pandemic and social isolation. Mental health experts worry that there will be an uptick in stress-related disorders including depression, anxiety, substance abuse and post-traumatic stress disorder.

Though Congress is considering a bill to expand Medicare and Medicaid coverage of telehealth services from therapists and social workers in an attempt to begin tempering a possible mental-health crisis, mental health organizations still question the already-overwhelmed healthcare systems capacity to aid Americans when the quarantine is over.

Healthcare and government officials alike warn that a mixture of social distancing, exposure to death-related trauma, unemployment and other factors are expected to contribute to an increase of mental-health disorders among Americans for many years to come.

In the meantime, viral social media posts point to feelings that many people share.

For example, not knowing what day it is:

Or, the toils of trying to attend school from home:

And having to work alongside family members for the first time:

While hard data about the rates of mental illness during the pandemic are not yet available, there is plenty to suggest that people are looking for ways to cope with the excess of time that they are spending at home. According to Google Trends data, U.S. searches for the words positivity, self-care, baking and painting reached peak popularity in April.

There is scientific evidence that creating art has cognitive benefits. A growing body of research suggests that art therapy, or the practice of treating patients with mental health disorders with art-related activities, can reduce stress and anxiety as well asimprove symptoms of neurological and age-related disorderssuch as dementia and Alzheimers.

Researchers have foundthat painting, drawing, sculpting and even scribbling have the ability to stimulate the centers in the brain related to pleasure and reward. Psychotherapists, hospitals and schools across the country have adopted art therapy methods with positive results.

The practice has also been used on non-cognitive disorders. Mayo Clinics Slaggie Family Cancer Education Center offers art therapy to its patients. One of the reasons art therapy is helpful is because it can be used as a tool for self-expression and working through feelings; it is a way to convey emotions, hopes and concerns. While making art, the creative corner of the brain takes over, Megan Roessler, a staff member at the Slaggie Center,wrote in a blog post.

But if creating art is not your forte, similar benefits have been found for simply viewing art. Some researchers have found that browsing through an art gallery can help lower the bodys concentration of the stress hormone cortisol and increase that of the pleasure hormone dopamine.

While there may not be a way to physically access your favorite Smithsonian museum in the current climate, there is still plenty of art waiting to be viewed online. Some of the worlds most acclaimed museums are offering online access to some of their exhibits.The Louvreand theVatican Museumhave stunning virtual tours. Other museums, including theMetand theNational Gallery, are allowing visitors to access interactive photo galleries.

In addition, the hashtags#covidartand#covidartmuseumhave amassed more than 100,000 posts on Instagram. Artists from all over the world are connecting by sharing their creations via these hashtags. And you dont have to scroll far to find a piece thats relatable to what you may be going through.

Maybe youre feeling thankful for our healthcare workers:

Or looking for a way to escape the confines of your home:

Or reminiscing about that quarantine cut youre already regretting:

Or even laughing to keep from crying:

So consider picking up a paintbrush or viewing someone elses creations online. You may be surprised to find that art-related activities are effective stress relievers for you. Regardless,prolonged activation of the bodys stress system is harmful. There are countless other activities that have stress-relieving effects, including exercising and viewing nature. During this time, it is important to find ones that are effective for you.

This article is reprinted with permission from Capital News Serivce

The Southern Maryland Chronicle is a local, small business entrusted to provide factual, unbiased reporting to the Southern Maryland Community.While we look to local businesses for advertising, we hope to keep that cost as low as possible in order to attract even the smallest of local businesses and help them get out to the public. We must also be able to pay employees(part-time and full-time), along with equipment, and website related things. We never want to make the Chronicle a pay-wall style news site.

To that end, we are looking to the community to offer donations. Whether its a one-time donation or you set up a reoccurring monthly donation. It is all appreciated. All donations at this time will be going to furthering the Chronicle through hiring individuals that have the same goals of providing fair, and unbiased news to the community. For now, donations will be going to a business PayPal account I have set-up for the Southern Maryland Chronicle, KDC Designs. All business transactions currently occur within this PayPal account. If you have any questions regarding this you can email me at [emailprotected]

Thank you for all of your support and I hope to continue bringing Southern Maryland the best news possible for a very long time. David M. Higgins II

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How art can help relieve stress during social isolation - The Southern Maryland Chronicle

Healthcare for a whole range of non-life-threatening illnesses, from dentistry to physiotherapy, has been put on hold since the outbreak of coronavirus in Ireland, in both the public and private health system. The Irish Times asked readers to tell us how they have been affected. This is a selection of the responses we received.

Due to the sensitive nature of health information, some names have been withheld on request.

I have found three lumps in my breast and have family history my mother has had breast cancer twice and my first cousin is just finished treatment for it. I had an appointment in St Vincents Private for March 26th and it was cancelled. Nobody can tell me when I will be able to get an appointment now. I have health insurance. Three lumps and a family history of breast cancer, and I am not seen as urgent. Sarah Donohoe

I went in for cataract removal in the Mater Private on February 20th. While the cataract was removed, the IOL (intraocular lens) wasnt inserted as the timeline to complete it ran out. It was rescheduled for March 19th but the HSE took over the hospital and my procedure was postponed. I am still waiting to be called by my consultant, but am giving it little/no hope as she is prevented from operating on private patients. I am in limbo and dont know what to do. I cannot see through my right eye. Tom Kennedy

I am 72 and my scheduled April knee replacement was cancelled because the Santry clinic was commandeered by the HSE. The private hospitals now have a 15 per cent bed occupancy and the public side have an abundance of beds. My surgeon informs me that I will be added to the bottom of the public waiting list (no complaint with that) and he is unsure if the private hospitals will ever reopen. The pre-Covid waiting time for an elective public joint replacement was four years (two years for a consultation and two years on the surgery list). If I stop paying the family VHI I could buy a golf buggy and cope with my golf, or pay for the surgery in another country like Romania. The only reason for having private health insurance is to cover whats not provided in any meaningful sense by the HSE - joint replacement, cataracts and benign surgery and if you get cancer, a heart attack or a stroke just rock up to hospital and you get immediate excellent treatment. Dr Michael Foley

Im from Cork. I suffer from chronic pain as a result of complications from numerous surgeries. At the end of last year I moved to Spain to access medical cannabis while waiting on the license at home that my GP and pain consultant applied for. My license was just approved this week in Ireland, however now I am stuck in Spain and unable to access medical cannabis here. Alicia Maher

Having suffered from thyrotoxicosis as a result of Graves Disease for almost two years, I was due to receive a thyroidectomy on March 31st. I had been advised by various consultants that definitive treatment was required, as my condition was not responding well enough to anti-thyroid medication to allow me to reduce the dosage. This medication is not considered safe to continue for longer than 18 months due to increased risk of side effects. I have now been consuming a high dose for 21 months.

On March 26th, my surgery was cancelled until further notice. I remained hopeful that if the hospitals did not become overwhelmed, it might soon be considered safe for my procedure to go ahead. In the meantime, I was advised to continue with my routine blood tests (every six weeks) and to now request that my liver function and full blood count be checked. This week, I received a letter from my endocrinologist stating that my surgery will not proceed until the Covid-19 situation has ended completely.

In addition to this, I also suffer from Graves ophthalmopathy as a result of my auto-immune thyroid condition. This creates numerous difficulties in my day-to-day life including pain, sleep disruption, and interference to my vision. I was referred to an ophthalmologist last November, and in February received my appointment letter, dated for June. When I attempt to call this ophthalmologists clinic, I am met with a pre-recorded message stating that the clinic is closed and that I should not leave a voicemail as it will not be received.

I am a private patient and all treatment has therefore been within the private healthcare system. While I felt that the decision to have the countrys private hospitals operate publicly during this crisis was a fair one, I feel my healthcare for a condition I am actually currently suffering from, is being sacrificed for the potential healthcare of those who may suffer from Covid-19 in the future.

I am now at my wits end; I feel the money I pay for health insurance is now putting me at a disadvantage. Necessary healthcare, which is my right, is being withheld despite the hospitals in Cork not being overwhelmed by Covid patients. Michelle ORegan

I was diagnosed with prostate cancer on March 6th, and told that treatment would be either a prostatectomy, or radiology combined with hormone therapy. The prostatectomy was apparently ruled out by the specialist, due to the coronavirus emergency. I had a telephone consultation with the radiologist, who made an appointment for a CT scan for March 31st at 9.45am. I arrived at the hospital at 9.15. I got a call from the specialist as I arrived to say that the procedure had been cancelled. He subsequently sent a letter to my GP, copied to me, which said I think it is safe to defer his treatment until later in the summer.

My four-year-old daughter needs two teeth removed via general anaesthetic. She has been given two antibiotics and is on a third from a urinary infection she got from the antibiotics. This is going on a month and a half now and she cannot eat with pain. We are told that dentists cannot use general anaesthetic at the moment due to Covid restrictions! I have spent the month on the phone going from pillar to post with dentists, the HSE, and politicians.

My GP referred me publicly and privately for colonoscopy and scope due to ongoing symptoms, unaware these procedures have all been cancelled.

Had an appointment for Cappagh Hospital for March 24th. Cancelled at five days notice. Still no update as to when it will happen.

I had an appointment for a knee replacement in April, which was cancelled. I am in pain and on daily medications. I cannot walk 50 metres now.

I was due to have surgery in Galway Clinic on March 23rd. I got a call on Friday 20th to say the surgery had been cancelled, as the clinic had to close. I am in serious pain on a daily basis. I pay VHI.

I spoke with my GP last Thursday, who requested a referral to the breast clinic. I got a letter today with an appointment for next Tuesday. It was super efficient.

I was given blood tests from the GP, since I had not been feeling well. I was told I had a deficiency of B12, which probably explains some depression and no energy. I was told I needed two injections a week for three weeks, then every three months. This was put on hold due to virus.

Only a small issue, but I had samples sent away a month ago to confirm a fungal infection. I have not heard back yet, have had no blood tests as I was told would take place within two weeks, and no updates from GP. My toe is in bad way, and I have to clean it daily and be careful with walking/ footwear so as not to pull at the nail or damage it.

I have recently been diagnosed with prostate cancer. I have had the treatment options explained to me but there is no treatment available for anyone with prostate cancer during the Covid emergency. My cancer is at an early stage, and I am not in urgent need of treatment. I fully understand that my case has to wait until the crisis is resolved. The oncologist has promised to contact me in July to review the situation. If there is still no prospect of treatment at that time I will begin to be worried.

I have been diagnosed with a neurological condition called CIDP. I cannot get an appointment to see my consultant neurologist in his rooms. Martina OFlaherty

I am due to have an arthroscopy and surgery to repair my rotator cuff in my right shoulder, and steroid injections in both knees for pain/arthritis.

I cannot get a scan either public or private. My doctor has sent requests too both. I had a surreal conversation from the Mater Private Cork, who phoned me to say they cannot see me as a private VHI patient, I then offered to pay them directly, to no avail. They also could not see me as a public patient. When I asked how could they see me. The receptionist who was very nice said they were only scanning patients who were put forward by specialists who worked for the Mater Private. I know you might think a sinus is a small thing in todays world, but this is seriously infected. I am popping antibiotics like theres no tomorrow.

I have a familial tendency to bowel cancer, which my father died from in his 60s. I am 68. I have had a number of colonoscopies in recent years and on each occasion have had a number of pre-cancerous polyps removed. My last one was in February 2019 after which the surgeon told me to come back in a year. I had an appointment arranged for March 24th, but all colonoscopies were cancelled from that day onwards. I recently received an appointment for sometime in July, but I understand that this is just a possibility and that the HSE have given the hospital no dates on which they may resume. I am worried.

My surgery was due in April at the Blackrock Clinic, cancelled due to private hospital takeover. I am very disappointed. It is not life or death, but with 2.2 million people with private insurance, the HSE is causing another crisis. Remove private work from public hospitals and leave the private sector alone.

Link:
Healthcare on hold: I cannot see through my right eye - The Irish Times

INTRODUCTION:

The hobnail variant of papillary thyroidcancer(PTC) is rare. Intrathyroid parathyroid adenoma (ITPA) is also rare. Co-ocurrence of PTC and ITPA in the same thyroid lobe is extremely rare. Likewise, primary hyperparathyroidism with such non-medullary thyroid carcinoma is rare. The specific molecular profile of hobnail PTC (HPTC) is different from the classic, poorly differentiated and anaplastic variants and may contribute to its aggressive behavior. HPTCs genetic profile remains unclear.

A 61-year-old woman presented to our endocrine clinic with generalized aches, bone pain, polyuria, and right neck swelling of a few months duration. Laboratory findings revealed hypercalcemia and hyperparathyroidism. Ultrasound of the neck showed 4.6cm complex nodule within the right thyroid lobe. Sestamibi scan suggested parathyroid adenoma in the right thyroid lobe. Fine-needle aspiration (FNA) revealed atypical follicular lesion of undetermined significance. She underwent right lobectomy, which normalized the intraoperative intact parathyroid hormone levels. Final pathology with immunohistochemical stains demonstrated HPTC and IPTA (2cm each). Next-generation sequencing investigated the mutation spectrum of HPTC and detected BRAFV600E mutation.

A parathyroid adenoma should not exclude the diagnosis of thyroid carcinoma. Thyroid evaluation is needed for patients with primary hyperparathyroidism to prevent missing concurrent thyroid cancers. Cytomorphologic features to distinguish thyroid from parathyroid cells on FNA cytology must be considered. Immunohistochemical stains are important. BRAFV600E is the most common mutation in HPTC. This is possibly the first reported case of HPTC and ITPA co-occurring within the same thyroid lobe. Studies that define other molecular abnormalities may be useful as therapeutic targets.

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First ever case report of co-occurrence of hobnail variant of papillary thyroid carcinoma and intrathyroid parathyroid adenoma in the same thyroid...

Vaginas: they give us pleasure, cause us pain, and literally give us life. They're pretty damn amazing, but how well do you actually know yours?

Sexual wellness is a massive part of self-care, and the best way to look after yourself is to know exactly what's going on down there. And we're all different, so normal for you might not be for your mates. Nerding up on your nethers isn't only a good idea to help you get maximum enjoyment from masturbation and sex (although, that is a very good reason), but also so that you can easily spot the signs if something feels off.

Worryingly, it seems a lot of people are still mystified by the vagina and the vulva (the external part of the genitals). A 2019 YouGov poll found that 45% of women and 59% of men couldn't even point out the vagina on a diagram of female genitalia. They were also asked to point out the clitoris, which thankfully 71% of women, and 69% of men correctly identified. That's still almost one in three women who don't know where their clitoris is though yikes.

But now that we're in lockdown with a lot of time of our hands, why not spend some of it getting better acquainted with your vagina? GLAMOUR is here to get you clued up on your down there, busting myths and dropping some pretty amazing facts too. And we're not just talking about vaginas, either. We've got the lowdown on the ins and outs (so to speak) of your labia, clitoris, perineum, G-spot, even the A-spot (yes, it's a thing) the whole lot.

So pull up a chair, maybe grab a mirror and get ready to learn 20 amazing vagina facts. If this inspires you to indulge in a little self-care/love read our expert tips on orgasming on your own or check out our roundup of the best sex toys out there. You're welcome.

Link:
20 Facts You Need To Know About Your Vagina And Vulva - Glamour UK

Weight loss relies on a fairly straightforward equation: To drop the number on the scale, you must consume fewer calories than your body burns. With this in mind, it seems logical that cutting as many calories as possible can help you shed pounds faster. Makes sense, right?

News flash: Your weight-loss diet shouldn't leave you starving.

Image Credit: AndreyPopov/iStock/GettyImages

Hate to break it to you, but this calorie-slashing strategy may actually be sabotaging your efforts. In fact, eating too far below your specific calorie needs not only halts weight loss but may also negatively affect your health.

The rub is that everyone's calorie needs are different, so there's no one-size-fits-all when it comes to calorie counts for weight loss.

Here, Lisa Moskovitz, RDN, dietitian and founder of The NY Nutrition Group, helps you identify red flags that indicate you're not eating enough, plus offers guidance on how to determine the right number of calories you personally need for healthy, safe weight loss.

In general, women shouldn't cut their calories below 1,200 a day and men should stay above 1,500 unless they're under the supervision of a health care professional.

When you begin a weight-loss plan, your body might need time to adjust to eating fewer calories, so a hunger pang here or there is common. But if you're constantly craving your next meal or snack after a few days, something might be up.

"Thinking about food all the time is a sign your body needs more," Moskovitz says. That could mean more calories and/or a better balance of food groups to supply all necessary nutrients.

In other words, your diet might be lacking in major macros like carbohydrates, fats and proteins or other filling nutrients like fiber, which can keep your blood sugar stable and appetite in check.

That's why it's essential to heed your hunger cues. "Even if you think you ate enough based on specific portions, that doesn't mean your body agrees," Moskovitz says.

Lightheadedness is another indication that you're not eating enough. "Your blood sugars may be too low and thus causing you to feel weak or woozy," Moskovitz explains.

That's because when your blood sugar dips below what your body needs to function properly, your systems go into conservation mode to use less energy, according to Harvard Health Publishing.

This faint feeling may also be a result of dehydration, Moskovitz says. Without sufficient water, your blood volume decreases, leading to a decline in blood pressure, per Harvard Health Publishing. When this happens, your brain doesn't get enough blood, causing dizziness.

With that said, it's always a good idea to talk to your doctor if you experience these symptoms to be sure that you're not dealing with a more serious underlying health condition, Moskovitz says.

If your workouts are tougher than usual, you may need to evaluate what and how much you're eating.

Image Credit: Tero Vesalainen/iStock/GettyImages

Wiped out during workouts? Poor performance in the gym is a hallmark of consuming too little food, Moskovitz says.

Here's why: Calories equal energy, so if you're not ingesting an adequate amount, your body must use all its strength to support basic functions and it won't have much oomph left over for anything extra, including your workouts.

Not only does undereating sap your energy, it also curbs your ability to build lean muscle, Moskovitz adds. Since muscle burns more calories than fat, even at rest, having more of it aids weight loss.

Remember, to gain muscle, you need to pack plenty of protein onto your plate, per the American College of Sports Medicine. If you're over-restricting calories, though, odds are you're not getting enough of the macronutrient.

If you're in a calorie deficit, you should be aiming for 1.3 grams of protein per kilogram of body weight (a kilogram is about 2.2 pounds, for the record).

A diet that's too low in calories can leave you backed up.

"Not eating enough means there is nothing to push through your digestive tract, which can lead to bowel movement irregularities such as constipation," Moskovitz says.

Plus, a lot of trendy diets ditch (or significantly cut) carbs including healthy whole grains, veggies and fruits which are full of fiber. The thing is, fiber bulks up your poop and helps food pass from your stomach to your intestines, per the U.S. National Library of Medicine. So, without enough of it, your stool gets, well, sort of stuck.

To avoid this and speed up your stool, Moskovitz recommends eating at regular intervals throughout the day with plenty of gut-healthy fiber as well as hydrating with water to keep things moving smoothly.

Psst: A study published February 2015 in the Annals of Internal Medicine found that simply aiming to eat 30 grams of fiber each day could help you lose weight as effectively as a more complicated diet.

If your weight loss grinds to a halt, you might think that slashing more calories is the solution. It's probably not.

Though it sounds counterintuitive, your low-calorie diet could be the reason you've stopped shedding pounds in the first place.

"Whenever you limit calories to lose weight, your metabolism can go through a process called adaptive thermogenesis," Moskovitz says. When this happens, your metabolism may slow down.

Essentially, when you cut too many calories, your body goes into survival mode, so it burns fewer calories to preserve energy. In short, your body is protecting you from what it perceives as starvation.

To make matters worse, restrictive dieting may even raise your levels of cortisol, a stress hormone linked to increased appetite and belly fat, according to a May 2010 study published in Psychosomatic Medicine.

Too-few calories can leave your immune system in the lurch.

Image Credit: PeopleImages/E+/GettyImages

Catching colds regularly? Your low-calorie diet may be to blame.

"Eating too little can negatively affect the immune system and stress out the body," Moskovitz says.

When this happens, your body produces fewer lymphocytes, aka infection-fighting white blood cells, according to the Cleveland Clinic. Consequently, with lower lymphocyte levels, you run a greater risk of getting sick.

What's more, restrictive dieting "usually means you're not getting key immune-building nutrients like vitamin C, zinc, vitamin D and probiotics," Moskovitz adds.

Put simply, your body's defenses suffer when you cut too many calories in the form of wholesome, nutritious foods.

First, determine the number of calories you should be eating each day to maintain your weight by using the chart in the Dietary Guidelines for Americans, which breaks it down by age, sex and physical activity level.

For healthy weight loss (about 1 pound per week), you should aim to cut about 500 calories a day from that amount, according to the Mayo Clinic. (As long as you're not falling below 1,200 calories for women or 1,500 calories for men.)

To make it even easier on yourself, you can download LIVESTRONG.com's MyPlate tracker, which will do the calculating for you. The app also makes it easy to update your needs as your weight and exercise regimen change.

Moskovitz suggests consulting with a registered dietitian, who can take a look at your complete medical, lifestyle and diet history. A nutrition expert can also help you devise a proper meal plan to ensure you get the nutrients you need when cutting calories.

Link:
6 Signs Youre Not Eating Enough Calories on Your Weight-Loss Diet - LIVESTRONG.COM

InForGrowth Market Research offers a most recent distributed report on Global Adenomyosis Treatment industry examination and figure 2019-2025 conveying key bits of knowledge and giving an upper hand to customers through a point by point report. The report contains XX pages which profoundly displays on current market investigation situation, up and coming just as future chances, income development, evaluating and gainfulness. The Global pandemic of COVID19 calls for redefining of business strategies. This Adenomyosis Treatment Market report includes the impact analysis necessary for the same

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