The top 10 science stories of 2019 | NOVA – NOVA Next
Posted: December 24, 2019 at 9:46 am
1. New Horizons nails the most distant flyby in history
Just 33 minutes after ringing in the New Year, scientists at the Johns Hopkins University Applied Physics Laboratory cheered and threw confetti a second time. The New Horizons spacecraft had just conducted a flyby of a Kuiper Belt object 4 billion miles from Earth. And as the sun rose on January 1, New Horizons beamed back its first close-up images of the 19-mile-long peanut-shaped space rock, officially named 2014 MU69.
Images eventually revealed 2014 MU69 (initially nicknamed Ultima Thule), to be a surprisingly flat contact binary, a body composed of two once-separated rocks that slowly gravitated toward each other until they lightly touched and fused. Scientists believe the flyby data could offer insight into how planets formed in our solar system billions of years ago.
In November, NASA changed the rocks nickname from Ultima Thule, a term with links to the Nazi party, to Arrokoth, which means sky in the Powhatan/Algonquian language.
2014 MU69 is revealed to be a two-tiered snowman. According to the New Horizons team, this image supports the idea that planets in our system formed as bits of raw planetary matter coalesced over time. Image Credit: NASA/Johns Hopkins University Applied Physics Laboratory/Southwest Research Institute
Twelve years after a first patient was declared to be rid of HIV, another person achieved a similar milestone this year. In March, with the help of a stem cell transplant from a virus-resistant donor, the anonymous individual entered long-term remission from HIV.
In both cases, remission followed a transplant of bone marrow from a person with a mutation in the gene that encodes the protein CCR5, which many HIV strains use to infiltrate cells. Neither treatment was originally intended to eliminate the infection itself, but to treat blood cancers that had spread in both individuals.
While the intervention is likely to be effective in only a small fraction of HIV-positive individuals, the 2019 case shows that its efficacy was more than a one-time event.
In April, we were able to feast our eyes on the first-ever image of a black hole. The black hole, whose image was generated from data captured by a network of eight radio observatories that make up the Event Horizon Telescope, dwells in the center of a galaxy some 55 million light-years away from Earth.
As popular as the black hole image was, another aspect of the story that quickly unfolded online: the contribution of 29-year-old MIT scientist Katie Bouman, who crafted an algorithm to help translate the telescope data into the black hole image. Bouman, captured in a photo with a laptop, beaming behind her folded hands, quickly became a symbol for womens accomplishment in astronomy and computer science. But, Marina Koren writes for The Atlantic, This one image tapped into a multitude of questions about the role of women in science, the myth of the lone genius, and the pressure scientists have to promote themselves and their work on social media.
No one algorithm or person made this image, Bouman later wrote, referring to the black hole picture, in a Facebook post. It required the amazing talent of a team of scientists from around the globe and years of hard work to develop the instrument, data processing, imaging methods, and analysis techniques that were necessary to pull off this seemingly impossible feat.
CRISPR-Cas9 is a tool that lets scientists cut and insert small pieces of DNA at precise areas along a DNA strand. | Photo credit: Public Domain
In April, researchers began the first CRISPR-Cas9 gene-editing clinical trials in people in the United States. In the trials, scientists used CRISPR, a powerful gene-editing technique derived from an ancient bacterial immune system, to combat cancer and blood disorders. That month, two cancer patientsone with myeloma and one with sarcomawere treated using CRISPR.
In the cancer and blood disorder trials, researchers remove some cells from a patients body, edit the cells DNA using CRISPR, and inject the cells back in, now hopefully armed to fight disease, Tina Hesman Saey writes for Science News. But in another trial, conducted by Editas Medicine in Cambridge, Mass., researchers are using CRISPR to edit DNA directly in the human body by snipping a small piece of DNA out of cells in the eyes of people with an inherited form of blindness, Saey writes.
The trials come on the heels of Chinese scientist He Jiankuis gene-editing on twin girls born in November 2018, which was widely criticized as premature and highly unethical. .
Mammal fossils like this one, discovered by a team of paleontologists and paleobotanists led by Tyler Lyson in Corral Bluffs, Colorado, fill in a missing piece of the timeline of life. Image Credit: HHMI Tangled Bank Studios
This year, scientists gleaned new insight into the day the dinosaur-killing asteroid crashed into Earth 66 million years ago, and the first million years after the impact.
In April, paleontologist and graduate student Robert DePalma claimed to unveil an unprecedented time capsule of the asteroid-induced catastrophe. He reported finding scorched tree trunks and hundreds of well-preserved fossil fish beneath sediment at a site in North Dakota, forming a snapshot of the first minutes and hours after impact. (Some experts remain cautious about the finding, due in part to the fact that DePalmas discovery was first announced in a New Yorker article before publication of the peer-reviewed paper.)
Then, in October, new fossils that capture the million-year timeline of life after the dinosaurs died were revealed. Discovered in Colorados Corral Bluffs by paleontologist Tyler Lyson and his team, the fossils showcase the extraordinary resilience of life in the wake of disaster and help reveal the evolutionary journey of the mammals that survived the asteroid.
With the use of artificial intelligence on the rise, one serious flaw continued to make headlines in 2019: racial bias. In October, researchers announced that a particular algorithm, which predicts who might benefit from follow-up care and affects 100 million Americans, underestimates black patients need for additional treatment. The algorithm underestimates the health needs of black patients even when theyre sicker than their white counterparts.
Additionally, the U.S. remains one of the most dangerous developed nations in which to be pregnant and give birth, particularly for minorities. Pregnancy-related deaths are rising in the United States and the main risk factor is being black, Mike Stobbe and Marilynn Marchione write for AP News. A CDC report concludes black women, along with Native Americans and Alaska natives, are three times more likely to die before, during or after having a baby, and more than half of these deaths are preventable, Stobbe and Marchione write.
Also this year, researchers further investigated why black scientists are less likely to receive funding from the National Institutes of Health (NIH) than their white counterparts. A study published in October illustrated that topic choice contributes to the lower rates of NIH awards going to black scientists. Specifically, Jeffrey Mervis writes for Science Magazine, black applicants are more likely to propose approaches, such as community interventions, and topics, such as health disparities, adolescent health, and fertility, that receive less competitive scores from reviewers.
A replica of a fragment of a Denisovan finger found in Denisova Cave, Siberia, in 2008. Image Credit: Thilo Parg, Wikimedia Commons
New findings in 2019 added to anthropologists understanding of Denisovans, a species of early human that likely shared the planet with Homo sapiens as recently as 50,000 years ago.
This fall, scientists learned that although Denisovans DNA ties them more closely to Neanderthals, their fingers may have looked more like ours, suggesting Neanderthals broader digits evolved after their lineage split off from the Denisovans around 410,000 years ago. A few more fossils, Bruce Bower writes for Science News, plus genetic analyses indicated Denisovans were close relatives and occasional mating partners of Neanderthals and Homo sapiens tens of thousands of years ago. But there was too little evidence to say what Denisovans looked like or how they behaved.
Physicists reached a milestone in quantum computing this year, a method of computing that uses quantum physics to solve complex problems quickly.
In October, Google said it had achieved quantum supremacy. Its AI Quantum Team presented evidence that it had built a quantum computer that needs only 200 seconds to solve a problem that would have taken IBMs Summit, the worlds most powerful supercomputer, 10,000 years to crack. Though IBM disputed the claim, others in the computing community are tentatively optimistic about the breakthroughs promise. If validated, it may bring us closer to a future of ultra-efficient computing.
Just when you thought Saturn couldnt get any more awesome, it secured yet another claim to fame: the most known moons of any planet in our solar system (sorry, Jupiter).
On October 7, the International Astronomical Unions Minor Planet Center announced that researchers discovered an additional 20 moons orbiting Saturn, bringing its grand total to a whopping 82. Jupiter, the largest and oldest planet in our solar system, has 79.
The latest discoveries were made possible by Hawaiis Subaru telescope. A team led by Carnegie Sciences Scott S. Sheppard first eyed them in the spring of 2017, but because faraway moons are dim and tough to spot, researchers used Subaru to scan the skies periodically throughout the following years to confirm their finding. Then, they used a computer algorithm to link the data through time and confirm that the moons were indeed reliably orbiting Saturn.
Less than a week after the U.N. climate talks came to a close in Madrid this month, Australia recorded its hottest day ever, one day after its previous record. Just a few months ago, wildfires raged across not only the American West and Australian Outback but also Europe and the Amazon, an occurrence that many climatologists believe may have been exacerbated by climate change-induced drought and high temperatures. And in May, a United Nations report claimed that one million plant and animal species are on the verge of extinctionmore than in any other period in human historywith alarming implications for human survival. The warming climate, which heightens the effects of overfishing, pesticide use, pollution, and urban expansion is a major driver, the report concludes.
Three weeks ago, a bleak climate report, also from the U.N., predicted that global carbon emissions will climb despite promises from almost 200 nations to address climate change, propelling temperatures upward and threatening to shatter the threshold of 2C that scientists say would invite dramatic changes to ecology and the economy, Nathaniel Gronewald writes for Science Magazine. And many declared this months COP25 climate talks to be a massive failure.
But climate activists, particularly teens, have seized the spotlight this year. Greta Thunberg, a 16-year-old Swedish climate activist, was just named TIMEs Person of the Year. And at COP25, official youth constituency representatives expressed their disappointment to leaders and officials, Kartik Chandramouli writes for Mongabay. Do you want to be remembered as the ones who had the chance to act but decided not to as betrayers of our generation, of indigenous people and communities desperately fighting on the ground? Youth representatives said. We are rising, we are fighting and we will win.
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The top 10 science stories of 2019 | NOVA - NOVA Next
- 'CRISPR pill' instructs harmful bacteria to self-destruct - National Hog Farmer [Last Updated On: April 26th, 2017] [Originally Added On: April 26th, 2017]
- Highly sensitive CRISPR diagnostic tool created - BioNews [Last Updated On: April 26th, 2017] [Originally Added On: April 26th, 2017]
- More Tooth, More Tail in CRISPR Operations | GEN - Genetic Engineering & Biotechnology News (press release) [Last Updated On: April 26th, 2017] [Originally Added On: April 26th, 2017]
- Quick, Sensitive Diagnostic Tests with CRISPR - Technology Networks [Last Updated On: April 26th, 2017] [Originally Added On: April 26th, 2017]
- MPEG LA Invites CRISPR-Cas9 Patents to be Pooled in a One-Stop License - Yahoo Finance [Last Updated On: April 26th, 2017] [Originally Added On: April 26th, 2017]
- What Is CRISPR? - livescience.com [Last Updated On: April 26th, 2017] [Originally Added On: April 26th, 2017]
- CRISPR and Stem Cells Identify Novel Chlamydia Drug Targets - Genetic Engineering & Biotechnology News [Last Updated On: April 26th, 2017] [Originally Added On: April 26th, 2017]
- CRISPR webinar: HGF discusses IP landscape - Life Sciences Intellectual Property Review (subscription) [Last Updated On: April 27th, 2017] [Originally Added On: April 27th, 2017]
- CRISPR.com was for sale, and you won't guess who bought it - STAT [Last Updated On: April 27th, 2017] [Originally Added On: April 27th, 2017]
- CRISPR Pill May Be Key in Fight Against Antibiotic Resistance - Singularity Hub [Last Updated On: April 27th, 2017] [Originally Added On: April 27th, 2017]
- Intellia (NTLA), CRISPR Therapeutics (CRSP) Receive U.S. Patent for CRISPR/Cas9 Ribonucleoprotein Complexes - StreetInsider.com [Last Updated On: April 27th, 2017] [Originally Added On: April 27th, 2017]
- transOMIC technologies Launches transEDIT-dual CRISPR ... - PR Newswire (press release) [Last Updated On: April 27th, 2017] [Originally Added On: April 27th, 2017]
- Global CRISPR Market Forecast 2017-2025 - Research and Markets ... - Business Wire (press release) [Last Updated On: April 27th, 2017] [Originally Added On: April 27th, 2017]
- Quick, Sensitive Diagnostic Tests with CRISPR | Technology Networks - Technology Networks [Last Updated On: April 27th, 2017] [Originally Added On: April 27th, 2017]
- CRISPR/Cas9 and Targeted Genome Editing: A New Era in ... [Last Updated On: April 27th, 2017] [Originally Added On: April 27th, 2017]
- CRISPR - Wikipedia [Last Updated On: April 27th, 2017] [Originally Added On: April 27th, 2017]
- CRISPR Used To Modify Multiple Genes In Rice - Asian Scientist Magazine [Last Updated On: April 28th, 2017] [Originally Added On: April 28th, 2017]
- Current CRISPR Patent Dispute, Explained - CALIFORNIA [Last Updated On: April 28th, 2017] [Originally Added On: April 28th, 2017]
- CEOs of top gene-editing firms got huge compensation hikes last year - Boston Business Journal [Last Updated On: April 28th, 2017] [Originally Added On: April 28th, 2017]
- CRISPR-SMART Cells Regenerate Cartilage, Secrete Anti-Arthritis Drug - Genetic Engineering & Biotechnology News [Last Updated On: April 29th, 2017] [Originally Added On: April 29th, 2017]
- Another CRISPR Trial Begins - GenomeWeb [Last Updated On: April 29th, 2017] [Originally Added On: April 29th, 2017]
- China Is Racing Ahead of the US in the Quest to Cure Cancer With CRISPR - Gizmodo [Last Updated On: April 29th, 2017] [Originally Added On: April 29th, 2017]
- CRISPR Gene Editing - CRISPR/Cas9 - Horizon Discovery [Last Updated On: May 1st, 2017] [Originally Added On: May 1st, 2017]
- CRISPR | Broad Institute [Last Updated On: May 1st, 2017] [Originally Added On: May 1st, 2017]
- Questions and Answers about CRISPR | Broad Institute [Last Updated On: May 1st, 2017] [Originally Added On: May 1st, 2017]
- CRISPR Genome Engineering Resources | learn, share, and discuss [Last Updated On: May 1st, 2017] [Originally Added On: May 1st, 2017]
- CRISPR Technology Scientists on Their Gene Editing Tool - TIME [Last Updated On: May 1st, 2017] [Originally Added On: May 1st, 2017]
- Cas9 - Wikipedia [Last Updated On: May 1st, 2017] [Originally Added On: May 1st, 2017]
- Using CRISPR against cancer shows success in mice - Futurity - Futurity: Research News [Last Updated On: May 2nd, 2017] [Originally Added On: May 2nd, 2017]
- Using CRISPR to Find Treatments for Aggressive Pediatric Brain Cancer - Bioscience Technology [Last Updated On: May 2nd, 2017] [Originally Added On: May 2nd, 2017]
- CRISPR Eliminates HIV in Live Animals - Genetic Engineering & Biotechnology News [Last Updated On: May 2nd, 2017] [Originally Added On: May 2nd, 2017]
- The CRISPR patent dispute - Europe and the US - BioNews [Last Updated On: May 2nd, 2017] [Originally Added On: May 2nd, 2017]
- How Scientists Think CRISPR Will Change Medicine - TIME [Last Updated On: May 3rd, 2017] [Originally Added On: May 3rd, 2017]
- What you need to know about the legal battle over CRISPR patents - Genetic Literacy Project [Last Updated On: May 4th, 2017] [Originally Added On: May 4th, 2017]
- Scientists have eliminated HIV in mice using CRISPR - TechCrunch [Last Updated On: May 4th, 2017] [Originally Added On: May 4th, 2017]
- CRISPR Therapeutics Appoints Samarth Kulkarni, Ph.D. as President, Expanding Role Beyond Chief Business Officer ... - GlobeNewswire (press release) [Last Updated On: May 4th, 2017] [Originally Added On: May 4th, 2017]
- ECDC says risk from contaminated CRISPR kits low - CIDRAP [Last Updated On: May 4th, 2017] [Originally Added On: May 4th, 2017]
- CRISPR Could Transform the Way We Diagnose Disease - Gizmodo [Last Updated On: May 4th, 2017] [Originally Added On: May 4th, 2017]
- A cancer gene also grows stem cells, CRISPR in monkey embryo ... - Speaking of Research [Last Updated On: May 5th, 2017] [Originally Added On: May 5th, 2017]
- New CRISPR Technique Can Potentially Stop Cancer In Its Tracks - Wall Street Pit [Last Updated On: May 6th, 2017] [Originally Added On: May 6th, 2017]
- CRISPR gene-editing tool targets cancer's "command center" - Gizmag - New Atlas [Last Updated On: May 7th, 2017] [Originally Added On: May 7th, 2017]
- Update: CRISPR - Radiolab [Last Updated On: May 7th, 2017] [Originally Added On: May 7th, 2017]
- Cambridge gene editing firm CRISPR to use delivery tech honed ... - Boston Business Journal [Last Updated On: May 9th, 2017] [Originally Added On: May 9th, 2017]
- Oxford Genetics licenses CRISPR tech to power synbio push - FierceBiotech [Last Updated On: May 10th, 2017] [Originally Added On: May 10th, 2017]
- What You Need to Know About the New CRISPR Cancer Treatment - BOSS Magazine [Last Updated On: May 11th, 2017] [Originally Added On: May 11th, 2017]
- CRISPR: The Future of Medicine and Human Evolution - in-Training [Last Updated On: May 12th, 2017] [Originally Added On: May 12th, 2017]
- Intellia Therapeutics Announces Progress with CRISPR/Cas9 at the American Society of Gene & Cell Therapy Annual ... - GlobeNewswire (press... [Last Updated On: May 13th, 2017] [Originally Added On: May 13th, 2017]
- Pac-Man like CRISPR enzymes discovered - Lab News [Last Updated On: May 13th, 2017] [Originally Added On: May 13th, 2017]
- Coming age of CRISPR gene editing: What in heck is the 'Pink Chicken Project'? - Genetic Literacy Project [Last Updated On: May 15th, 2017] [Originally Added On: May 15th, 2017]
- Intellia moves closer to clinic with CRISPR tech - FierceBiotech [Last Updated On: May 15th, 2017] [Originally Added On: May 15th, 2017]
- Will CRISPR Technology Create a New "Human" Species? - Big Think [Last Updated On: May 15th, 2017] [Originally Added On: May 15th, 2017]
- Caribou Bioscience's CEO on CRISPR's legal and ethical challenges - TechCrunch [Last Updated On: May 16th, 2017] [Originally Added On: May 16th, 2017]
- Cut Out the Hype: Gene Editing With CRISPR and the Truth about Superhuman 'Designer Babies' - WhatIsEpigenetics.com (blog) [Last Updated On: May 16th, 2017] [Originally Added On: May 16th, 2017]
- CRISPR-Cas.org [Last Updated On: May 16th, 2017] [Originally Added On: May 16th, 2017]
- Synthego's genetic toolkit aims to make CRISPR more accessible - TechCrunch [Last Updated On: May 16th, 2017] [Originally Added On: May 16th, 2017]
- What is CRISPR? A Beginner's Guide | Digital Trends [Last Updated On: May 16th, 2017] [Originally Added On: May 16th, 2017]
- Geneticists Enlist Engineered Virus and CRISPR to Battle Citrus Disease - Scientific American [Last Updated On: May 16th, 2017] [Originally Added On: May 16th, 2017]
- Editas delays IND for Allergan-partnered CRISPR program - FierceBiotech [Last Updated On: May 16th, 2017] [Originally Added On: May 16th, 2017]
- Easy DNA Editing Will Remake the World. Buckle Up - WIRED [Last Updated On: May 16th, 2017] [Originally Added On: May 16th, 2017]
- Can CRISPR feed the world? - Phys.org - Phys.Org [Last Updated On: May 19th, 2017] [Originally Added On: May 19th, 2017]
- Gene-editing tool 'CRISPR' gaining massive attention - KMOV.com [Last Updated On: May 19th, 2017] [Originally Added On: May 19th, 2017]
- Fixing the tomato: CRISPR edits correct plant-breeding snafu - Nature.com [Last Updated On: May 19th, 2017] [Originally Added On: May 19th, 2017]
- Beyond just promise, CRISPR is delivering in the lab today - The Conversation US [Last Updated On: May 20th, 2017] [Originally Added On: May 20th, 2017]
- What is CRISPR-Cas9, and will it change the world? | Alphr - Alphr [Last Updated On: May 20th, 2017] [Originally Added On: May 20th, 2017]
- Fixing the Tomato: CRISPR Edits Correct Plant-Breeding Snafu ... - Scientific American [Last Updated On: May 20th, 2017] [Originally Added On: May 20th, 2017]
- This UK Biotech uses CRISPR-Cas9 To Fight Bacterial Resistance - Labiotech.eu (blog) [Last Updated On: May 21st, 2017] [Originally Added On: May 21st, 2017]
- Can CRISPR feed the world? | Horizon: the EU Research ... - Horizon magazine [Last Updated On: May 21st, 2017] [Originally Added On: May 21st, 2017]
- Will this gene-editing tool cure the diseases of the future? - Sacramento Bee [Last Updated On: May 23rd, 2017] [Originally Added On: May 23rd, 2017]
- How the CRISPR-Cas9 System is Redefining Drug Discovery - Labiotech.eu (blog) [Last Updated On: May 23rd, 2017] [Originally Added On: May 23rd, 2017]
- Scientists are using gene editing to create the perfect tomato for your salad - Quartz [Last Updated On: May 24th, 2017] [Originally Added On: May 24th, 2017]
- Fine-tuning CRISPR to Create Popular Mouse Models - Technology Networks [Last Updated On: May 25th, 2017] [Originally Added On: May 25th, 2017]
- Scientists Are Using CRISPR To "Program" Living Cells - Futurism - Futurism [Last Updated On: May 25th, 2017] [Originally Added On: May 25th, 2017]
- CRISPR gene editing puts the brakes on cancer cells - Cosmos [Last Updated On: May 26th, 2017] [Originally Added On: May 26th, 2017]
- Watch This Scientist Brilliantly Explain CRISPR to Everyone from a Child to a Ph.D. - Patheos (blog) [Last Updated On: May 27th, 2017] [Originally Added On: May 27th, 2017]
- Using CRISPR gene editing to slow cancer growth | FierceBiotech - FierceBiotech [Last Updated On: May 27th, 2017] [Originally Added On: May 27th, 2017]
- How A Gene Editing Tool Went From Labs To A Middle-School Classroom - NPR [Last Updated On: May 27th, 2017] [Originally Added On: May 27th, 2017]
- In Just a Few Short Years, CRISPR Has Sparked a Research Revolution - Futurism [Last Updated On: May 29th, 2017] [Originally Added On: May 29th, 2017]
- CRISPR Is Taking Over Science, Breaks Out Of Labs And Invades Schools - EconoTimes [Last Updated On: May 30th, 2017] [Originally Added On: May 30th, 2017]
- Gene-editing technique scientists hope will cure cancer and all ... - The Independent [Last Updated On: May 30th, 2017] [Originally Added On: May 30th, 2017]
- CRISPR Gene-Editing Can Cause Hundreds of Unexpected ... - ScienceAlert [Last Updated On: May 30th, 2017] [Originally Added On: May 30th, 2017]