Why Black Women Are Twice as Likely to Die of Endometrial Cancer and What MSK Is Doing to Change It – On Cancer – Memorial Sloan Kettering
Posted: October 5, 2021 at 6:33 pm
When Linda Collins was diagnosed with endometrial cancer in her early 60s, she wanted to find the best treatment possible.
After doing her research, she felt confident she would receive the care she needed at Memorial Sloan Kettering Cancer Center.
She also knew what she needed to give her peace of mind. When I called the MSK Patient Access Service to ask about an appointment, I told them that as a Black woman, I would feel more comfortable with a female doctor who is a person of color.
She explains that years before, I had a white, male gynecologist who dismissed concerns that I had. Respectfully, it seemed like he couldnt be bothered. And I have great insurance!
Linda searched the MSK website and knew she had found the doctor she hoped for in Carol Brown, a gynecologic oncology surgeon and MSKs Chief Health Equity Officer.
Dr. Carol Brown, gynecological oncology surgeon
Dr. Brown has devoted her career to improving cancer disparities that mean some groups of people suffer far worse outcomes, particularly Black people.
In May 2021, she launched an important new initiative as the leader of the Endometrial Cancer Equity Program (ECEP).Endometrial cancer develops in the lining of the uterus (womb) and is also sometimes referred to as uterine cancer.
The programs goals are to educate Black women about endometrial cancer, help those diagnosed find appropriate care, and ultimately find treatments to improve outcomes for all women facing the disease, like Linda.
The numbers are truly shocking.
Black women are nearly twice as likely to die of endometrial cancer as white women, even though the disease is actually slightly more common in white women than in Black women.
The number of cases of endometrial cancer is also on the rise, with the greatest increase among Black women.
Dr. Brown stresses that many factors play a role in the troubling disparity in endometrial cancer, including poorer access to health care in some communities, a lack of awareness among some providers, and research efforts that often have not included enough people who are Black, Hispanic, and Asian.
Dr. Brown says research also suggests another important factor may be a cruel twist of biology.
Dr. Brown points out that the disparity in survival between Black and white women diagnosed with endometrial cancer hasnt changed in four decades. Theres no question that if the difference was only about access to health care, the disparity would have at least narrowed. Thats what weve seen happen in cervical cancer and most forms of breast cancer, when you compare Black and white women. But not endometrial cancer.
One distinction coming into clearer focus is that Black women are more often diagnosed with rare but aggressive forms of endometrial cancer.
Black women are more likely to have papillary serous carcinoma of the endometrium as well as carcinoma sarcoma, Dr. Brown says. Cancers caused by these two types of cancer cells definitely lead to worse outcomes and that in itself is a biologic difference.
Ying Liu is a medical oncologist whose specialty is the genetic component of gynecological cancers. She works alongside Dr. Brown investigating cancer disparities.
Dr. Liu explains that one aspect we are looking at is whether these biological differences in the kinds of cancer more commonly found in Black women are not as well targeted by current treatments. That may explain some of the disparity in survival rates between Black and white patients.
The ultimate goal of research at MSK is to better understand these biological differences in endometrial tumors, down to the molecular level, and then use this knowledge to identify weaknesses in the tumors that are more common in Black women. Then, its about finding therapies to treat them.
Dr. Brown explains at MSK we probably have one of the largest groups of Black female patients in the country where we can analyze the genetics of their endometrial cancer tumors as well as their personal genetics.
Lindas diagnosis was an aggressive papillary serous carcinoma, the type that more commonly affects Black women. Fortunately, the cancer was caught at an early stage.
Linda recalls that within days of our first appointment, Dr. Brown performed a laparoscopic hysterectomy, which involves a much smaller incision, and also removed my fallopian tubes, ovaries, and nearby sentinel lymph nodes. To reduce the chance the cancer could come back, Linda underwent a short course of radiation.
Linda says of her treatment, the staff was just fantastic. And I love Dr. Brown. She was so proactive and always took the time to answer all my questions.
Today, Linda is doing the things she loves. She is a pillar of her community in the Bronx, serving as president of her building association, leading clothing drives for homeless shelters, and serving as a liaison with police associations, among other efforts.
After a 32-year career, most of it in government, she says I just love to serve people.
She also wanted to be sure she was around for her family, retiring from the working world in her mid-50s. She explains as a Black woman, you have the sense that your life expectancy might not be as long as the next person.
Dr. Brown and her colleagues hope their new initiative can help.
Since May 2021, the ECEP has participated in community events that have reached more than 500 women in predominately Black neighborhoods that stretch across Long Island, Brooklyn, and Queens.
In addition, Dr. Brown and colleagues including MSK nurse practitioner Latasha Anderson-Dunkley have screened over 20 women at high risk who have been identified through the ECEP. The goal is to assess whether the women have cancer or precancerous conditions and get them appropriate care.
Dr. Brown says its particularly important that women and their providers are aware of endometrial cancer because as cases rise, the symptoms of the disease are not always clear cut.
Traditionally, providers have focused on symptoms that include bleeding in post-menopausal women, who often have other symptoms such as obesity and diabetes, she explains. But this cancer can present as just a heavier-than-usual period bleeding in your 40s. Thats true of all women and particularly Black women.
For Linda, making women aware of how they can protect their health is just what the doctor ordered. To me, outreach and education is so important, because you dont know what you dont know. Too often, this kind of outreach doesnt happen in communities of color. But if it does, it can save lives.
Key Takeaways
Read the original post:
Why Black Women Are Twice as Likely to Die of Endometrial Cancer and What MSK Is Doing to Change It - On Cancer - Memorial Sloan Kettering
- Definition Of female reproductive system |Genetic ... [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Female - Wikipedia, the free encyclopedia [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Impact of Genetic Selection on Female Fertility - eXtension [Last Updated On: May 21st, 2015] [Originally Added On: May 21st, 2015]
- X chromosome - Genetics Home Reference [Last Updated On: May 31st, 2015] [Originally Added On: May 31st, 2015]
- How Chromosomes Determine Sex - About [Last Updated On: May 31st, 2015] [Originally Added On: May 31st, 2015]
- Galaxy Of Genetic Differences Between Men & Women [Last Updated On: June 10th, 2015] [Originally Added On: June 10th, 2015]
- Difference between Male and Female Chromosomes [Last Updated On: July 3rd, 2015] [Originally Added On: July 3rd, 2015]
- Female Age and Chromosome Problems in Eggs and Embryos [Last Updated On: July 10th, 2015] [Originally Added On: July 10th, 2015]
- Pathology and Genetics of Tumours of the Breast and Female ... [Last Updated On: July 14th, 2015] [Originally Added On: July 14th, 2015]
- Sex - Wikipedia, the free encyclopedia [Last Updated On: July 14th, 2015] [Originally Added On: July 14th, 2015]
- Sexual differentiation - Wikipedia, the free encyclopedia [Last Updated On: July 24th, 2015] [Originally Added On: July 24th, 2015]
- XY sex-determination system - Wikipedia, the free encyclopedia [Last Updated On: July 24th, 2015] [Originally Added On: July 24th, 2015]
- The Female Form: Embrace Your Genetics and Find Beauty in ... [Last Updated On: August 21st, 2015] [Originally Added On: August 21st, 2015]
- Female Hereditary Hair Loss Treatment & Genetic Testing ... [Last Updated On: August 28th, 2015] [Originally Added On: August 28th, 2015]
- Female Infertility Genetic Causes | RSC New Jersey [Last Updated On: September 19th, 2015] [Originally Added On: September 19th, 2015]
- Spectacular Genetic Anomaly Results in Butterflies with ... [Last Updated On: September 24th, 2015] [Originally Added On: September 24th, 2015]
- Tortoiseshell cat - Wikipedia, the free encyclopedia [Last Updated On: September 25th, 2015] [Originally Added On: September 25th, 2015]
- The Genetics of Calico Cats - Department of Biology [Last Updated On: September 25th, 2015] [Originally Added On: September 25th, 2015]
- Human Genetics - Mendelian Inheritance 5 [Last Updated On: February 9th, 2016] [Originally Added On: February 9th, 2016]
- Androgenetic alopecia - Genetics Home Reference [Last Updated On: February 9th, 2016] [Originally Added On: February 9th, 2016]
- X chromosome - Wikipedia, the free encyclopedia [Last Updated On: February 23rd, 2016] [Originally Added On: February 23rd, 2016]
- Davis Angus Foss, Oklahoma [Last Updated On: March 2nd, 2016] [Originally Added On: March 2nd, 2016]
- Y chromosome - Wikipedia, the free encyclopedia [Last Updated On: March 10th, 2016] [Originally Added On: March 10th, 2016]
- Molecular Genetics Laboratory of Female Reproductive Cancer [Last Updated On: May 20th, 2016] [Originally Added On: May 20th, 2016]
- Genetics and Inheritance - National Fragile X Foundation [Last Updated On: May 25th, 2016] [Originally Added On: May 25th, 2016]
- Genetics - X Linked Problems - The Biology Corner [Last Updated On: June 2nd, 2016] [Originally Added On: June 2nd, 2016]
- Nicole Kush Female Cannabis Seeds by DNA Genetics and ... [Last Updated On: July 24th, 2016] [Originally Added On: July 24th, 2016]
- A gay Gene - Is Homosexuality Inherited Assault On Gay ... [Last Updated On: August 7th, 2016] [Originally Added On: August 7th, 2016]
- Cat coat genetics - Wikipedia, the free encyclopedia [Last Updated On: August 24th, 2016] [Originally Added On: August 24th, 2016]
- Cloning - Learn Genetics [Last Updated On: August 24th, 2016] [Originally Added On: August 24th, 2016]
- Homosexuality - Conservapedia [Last Updated On: September 21st, 2016] [Originally Added On: September 21st, 2016]
- Science & Health, Colleges Around Cincinnati, University ... [Last Updated On: September 23rd, 2016] [Originally Added On: September 23rd, 2016]
- Elephant - Wikipedia, the free encyclopedia [Last Updated On: September 28th, 2016] [Originally Added On: September 28th, 2016]
- Supercourse: Epidemiology, the Internet, and Global Health [Last Updated On: October 7th, 2016] [Originally Added On: October 7th, 2016]
- Glossary - PBS: Public Broadcasting Service [Last Updated On: October 17th, 2016] [Originally Added On: October 17th, 2016]
- Male - Wikipedia [Last Updated On: October 30th, 2016] [Originally Added On: October 30th, 2016]
- Female - Wikipedia [Last Updated On: October 30th, 2016] [Originally Added On: October 30th, 2016]
- Mount Sinai Health System - New York City | Mount Sinai ... [Last Updated On: November 5th, 2016] [Originally Added On: November 5th, 2016]
- Calico cat - Wikipedia [Last Updated On: November 23rd, 2016] [Originally Added On: November 23rd, 2016]
- Mosaic (genetics) - Simple English Wikipedia, the free ... [Last Updated On: November 25th, 2016] [Originally Added On: November 25th, 2016]
- Calico Cats - TheCatSite.com Community [Last Updated On: November 30th, 2016] [Originally Added On: November 30th, 2016]
- Physical attractiveness - Wikipedia [Last Updated On: December 16th, 2016] [Originally Added On: December 16th, 2016]
- XY sex-determination system - Wikipedia [Last Updated On: January 27th, 2017] [Originally Added On: January 27th, 2017]
- Triple X syndrome - Wikipedia [Last Updated On: February 3rd, 2017] [Originally Added On: February 3rd, 2017]
- How African Americans Use DNA Testing to Connect With Their Past - The Atlantic [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- Hughes benefit from Wagyu fertility and eating quality - Queensland Country Life [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- Genetics Research Update - Island Eye News [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- DNA From Sperm Of Ex Partners Lingers In Female Flies And ... [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- Federal officials to review endangered status of Florida panther - Tampabay.com [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- Why Women Have Stronger Immune Systems than Men [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- Why does it seem like nobody cares about female concussions? - ESPN [Last Updated On: July 8th, 2017] [Originally Added On: July 8th, 2017]
- Geneticist says Florida panther still deserves endangered species protection - Tampabay.com [Last Updated On: July 8th, 2017] [Originally Added On: July 8th, 2017]
- How the living world was changed, by the woman who changed it - New Scientist [Last Updated On: July 8th, 2017] [Originally Added On: July 8th, 2017]
- Sharks could hold genetic secret to long life: Study - The Hindu [Last Updated On: July 8th, 2017] [Originally Added On: July 8th, 2017]
- Weekly genetics review: Registrations on the up for most beef breeds - Beef Central [Last Updated On: July 12th, 2017] [Originally Added On: July 12th, 2017]
- Orphan Black Science Recap: Guillotines Decide - The Mary Sue [Last Updated On: August 2nd, 2017] [Originally Added On: August 2nd, 2017]
- Genetics honour to CQ Brahman breeder Alf Collins - Beef Central [Last Updated On: August 2nd, 2017] [Originally Added On: August 2nd, 2017]
- Elad Gil and Silicon Valley's bright future in cryptocurrency, genetics and health tech - TechCrunch [Last Updated On: August 2nd, 2017] [Originally Added On: August 2nd, 2017]
- Top 6 myths about heart disease debunked - AsiaOne [Last Updated On: August 6th, 2017] [Originally Added On: August 6th, 2017]
- About a new pest: the bagrada bug - Santa Fe New Mexican [Last Updated On: August 6th, 2017] [Originally Added On: August 6th, 2017]
- Researchers Prepare to Explore the Genetics of Gender Identity, With Caution - The Wire [Last Updated On: August 6th, 2017] [Originally Added On: August 6th, 2017]
- Embryo editing 'corrects' genetic heart condition - The Guam Daily Post [Last Updated On: August 6th, 2017] [Originally Added On: August 6th, 2017]
- Cycling and gender: how and why male and female cyclists need to train differently - Cycling Weekly [Last Updated On: August 6th, 2017] [Originally Added On: August 6th, 2017]
- First human embryo editing experiment in US 'corrects' gene for heart condition - Washington Post [Last Updated On: August 6th, 2017] [Originally Added On: August 6th, 2017]
- Researchers Explore the Science of Gender Identity - NBCNews.com [Last Updated On: August 7th, 2017] [Originally Added On: August 7th, 2017]
- Selecting at negative 9 months - High Plains Journal [Last Updated On: August 7th, 2017] [Originally Added On: August 7th, 2017]
- Google Manifesto: Does Biology Explain Gender Disparities in Tech? - Live Science [Last Updated On: August 10th, 2017] [Originally Added On: August 10th, 2017]
- Damore Has Science On His Side - The American Conservative [Last Updated On: August 10th, 2017] [Originally Added On: August 10th, 2017]
- Memo to all tech bros: Sexism, not biology, holds women back - New Scientist [Last Updated On: August 10th, 2017] [Originally Added On: August 10th, 2017]
- Genetic strategies to reduce gilt feed and development costs - National Hog Farmer [Last Updated On: August 10th, 2017] [Originally Added On: August 10th, 2017]
- Dewmar International BMC, Inc. (DEWM) Announces Investment in New West Genetics, Better Than Expected Progress ... - Benzinga [Last Updated On: August 11th, 2017] [Originally Added On: August 11th, 2017]
- No, the Google manifesto isn't sexist or anti-diversity. It's science - The Globe and Mail [Last Updated On: August 11th, 2017] [Originally Added On: August 11th, 2017]
- Couples can tailor-make their babies - Khaleej Times [Last Updated On: August 11th, 2017] [Originally Added On: August 11th, 2017]
- Sarah Bush Lincoln receives the 2017 Women's Choice Award - Journal Gazette and Times-Courier [Last Updated On: August 11th, 2017] [Originally Added On: August 11th, 2017]
- A major blind spot in animal testing is endangering the lives of women - Quartz [Last Updated On: August 11th, 2017] [Originally Added On: August 11th, 2017]
- Jonathan Hoffman: Pima County should butt out of medical decisions - Arizona Daily Star [Last Updated On: August 14th, 2017] [Originally Added On: August 14th, 2017]
- Trans athletes should be able to compete in gender they identify with: centre for ethics in sport - CBC.ca [Last Updated On: August 14th, 2017] [Originally Added On: August 14th, 2017]
- Orphan Black Was Never About Cloning - Slate Magazine [Last Updated On: August 14th, 2017] [Originally Added On: August 14th, 2017]
- Techly Explains: Are twins genetic? - Techly [Last Updated On: August 14th, 2017] [Originally Added On: August 14th, 2017]
- How technology can deliver freedom from the male calf - The Indian Express [Last Updated On: August 15th, 2017] [Originally Added On: August 15th, 2017]