3D Co-localisation of Tumour And Bacterial Bioluminescence – Video

Posted: November 1, 2012 at 12:49 pm




3D Co-localisation of Tumour And Bacterial Bioluminescence
3D Co-localisation of Tumour And Bacterial Bioluminescence High Resolution In Vivo Bioluminescent Imaging for the Study of Bacterial Tumour Targeting (Movie S2 - journal.pone.0030940.s002.mov): Movie providing tomographic detail of source signal distribution of B. breve lux (green) 10 days post IV administration to mice bearing HCT116 FLuc (orange) expressing tumours. B. breve lux is observed in multiple disparate #39;clusters #39; within the tumour. - Engineered Bacteria Effectively Target Tumors, Enabling Tumor Imaging Potential in Mice Tumor-targeted bioluminescent bacteria have been shown for the first time to provide accurate 3-D images of tumors in mice, further advancing the potential for targeted cancer drug delivery, according to a study published in the Jan. 25 issue of the online journal PLoS ONE. http://www.sciencedaily.com Reference High Resolution In Vivo Bioluminescent Imaging for the Study of Bacterial Tumour Targeting PLoS ONE 7(1): e30940. doi:10.1371/journal.pone.0030940 http://www.plosone.org Abstract The ability to track microbes in real time in vivo is of enormous value for preclinical investigations in infectious disease or gene therapy research. Bacteria present an attractive class of vector for cancer therapy, possessing a natural ability to grow preferentially within tumours following systemic administration. Bioluminescent Imaging (BLI) represents a powerful tool for use with bacteria engineered to express reporter genes such as lux. BLI is traditionally used as a ...From:SergeytuleViews:195 0ratingsTime:00:34More inScience Technology

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3D Co-localisation of Tumour And Bacterial Bioluminescence - Video

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