3D Intratumoural Optical and μCT Imaging – Video

Posted: November 1, 2012 at 12:49 pm




3D Intratumoural Optical and mu;CT Imaging
3D Intratumoural Optical and µCT Imaging High Resolution In Vivo Bioluminescent Imaging for the Study of Bacterial Tumour Targeting (Movie S3 - journal.pone.0030940.s003.mov): Combined µCT and luminescence imaging of subcutaneous HCT116-luc2 tumour colonised by B. breve. Viable tumour (FLuc green/blue), vasculature (contrast agent -- red) and bacterial (orange/yellow) signals are visualised. - Engineered Bacteria Effectively Target Tumors, Enabling Tumor Imaging Potential in Mice Tumor-targeted bioluminescent bacteria have been shown for the first time to provide accurate 3-D images of tumors in mice, further advancing the potential for targeted cancer drug delivery, according to a study published in the Jan. 25 issue of the online journal PLoS ONE. http://www.sciencedaily.com Reference High Resolution In Vivo Bioluminescent Imaging for the Study of Bacterial Tumour Targeting PLoS ONE 7(1): e30940. doi:10.1371/journal.pone.0030940 http://www.plosone.org Abstract The ability to track microbes in real time in vivo is of enormous value for preclinical investigations in infectious disease or gene therapy research. Bacteria present an attractive class of vector for cancer therapy, possessing a natural ability to grow preferentially within tumours following systemic administration. Bioluminescent Imaging (BLI) represents a powerful tool for use with bacteria engineered to express reporter genes such as lux. BLI is traditionally used as a 2D modality resulting in images that are limited in ...From:SergeytuleViews:99 0ratingsTime:00:18More inScience Technology

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3D Intratumoural Optical and μCT Imaging - Video

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