Bacterial Bioluminescence in the GIT – Video

Posted: November 1, 2012 at 12:49 pm




Bacterial Bioluminescence in the GIT
Bacterial Bioluminescence in the GIT High Resolution In Vivo Bioluminescent Imaging for the Study of Bacterial Tumour Targeting (Movie S1 - journal.pone.0030940.s001.avi): Movie depicting rotational 3D optical tomography in combination with mouse anatomical atlas displaying luminescence in GIT of mice 27 days post oral administration of lux-labelled E. coli MG1655. - Engineered Bacteria Effectively Target Tumors, Enabling Tumor Imaging Potential in Mice Tumor-targeted bioluminescent bacteria have been shown for the first time to provide accurate 3-D images of tumors in mice, further advancing the potential for targeted cancer drug delivery, according to a study published in the Jan. 25 issue of the online journal PLoS ONE. http://www.sciencedaily.com Reference High Resolution In Vivo Bioluminescent Imaging for the Study of Bacterial Tumour Targeting PLoS ONE 7(1): e30940. doi:10.1371/journal.pone.0030940 http://www.plosone.org Abstract The ability to track microbes in real time in vivo is of enormous value for preclinical investigations in infectious disease or gene therapy research. Bacteria present an attractive class of vector for cancer therapy, possessing a natural ability to grow preferentially within tumours following systemic administration. Bioluminescent Imaging (BLI) represents a powerful tool for use with bacteria engineered to express reporter genes such as lux. BLI is traditionally used as a 2D modality resulting in images that are limited in their ability to anatomically ...From:SergeytuleViews:160 0ratingsTime:00:11More inScience Technology

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Bacterial Bioluminescence in the GIT - Video

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