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New findings on cell therapy to treat leukemia bring more encouraging news of the promise that this experimental area of cancer treatment holds for patients for whom conventional approaches do not work.

In the journal Science Translational Medicine, researchers from Memorial Sloan Kettering Cancer Center, New York, NY, report the results of the largest clinical study yet conducted in patients with advanced leukemia.

These show that 14 of the 16 patients - that is 88% - treated with genetically modified versions of their own immune cells, achieved complete remission - at least in the short term; the long-term effects of the therapy are yet to be tested.

Co-senior author Dr. Michel Sadelain, director of the Center for Cell Engineering at Memorial Sloan Kettering, describes the results as "extraordinary," saying they show how cell therapy might offer hope where other treatments have failed.

"Our initial findings have held up in a larger cohort of patients," he notes, "and we are already looking at new clinical studies to advance this novel therapeutic approach in fighting cancer."

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Cell therapy to treat leukemia shows more promise

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