Fat gene 'linked with skin cancer'

Posted: March 4, 2013 at 6:50 pm

4 March 2013 Last updated at 02:52 ET

A gene previously shown to be linked to obesity may also increase the risk of a deadly form of skin cancer, say researchers writing in Nature Genetics.

Analysis of data from 73,000 people, led by the University of Leeds, found a specific section of the "fat gene" was associated with malignant melanoma.

It is the first time the gene has been linked with a specific disease independently of weight.

The results suggest a wider role for the gene than originally thought.

Malignant melanoma is the fifth most common cancer in the UK with about 12,800 new cases and about 2,200 deaths each year.

An international team analysed genetic data from the tumours of 13,000 malignant melanoma patients and 60,000 unaffected individuals.

They found that those with particular variations in a stretch of DNA within the "fat gene" or FTO gene, called intron 8, could be at greater risk of developing melanoma.

Previous research linking the FTO gene with obesity found that variants in a section called intron 1 are linked with being overweight and overeating.

It's now clear we don't know enough about what this intriguing gene does

See the original post here:
Fat gene 'linked with skin cancer'

Related Posts

Comments are closed.

Archives