Public release date: 5-Mar-2013 [ | E-mail | Share ]

Contact: Phyllis Edelman pedelman@genetics-gsa.org 301-634-7302 Genetics Society of America

Bethesda, MDMarch 5, 2013 Listed below are the selected highlights for the March 2013 issue of the Genetics Society of America's journal, Genetics. The March issue is available online at http://www.genetics.org/content/current. Please credit Genetics, Vol. 193, MARCH 2013, Copyright 2013.

Please feel free to forward to colleagues who may be interested in these articles on cellular genetics; population and evolutionary genetics; genome integrity and transmission; and genome and systems biology.

ISSUE HIGHLIGHTS

Cellular Genetics: Systems genetics implicates cytoskeletal genes in oocyte control of cloned embryo quality, pp. 877-896 Yong Cheng, John Gaughan, Uros Midic, Zhiming Han, Cheng-Guang Liang, Bela G. Patel, and Keith E. Latham

Cloning by somatic cell nuclear transfer is a powerful technology that offers a unique means of dissecting developmental processes. This article reveals oocyte-expressed genes that support early cloned embryo development. The major category of genes encodes proteins associated with the subcortical cytoskeleton and cytoskeletal elements such as the spindle. Discovery that cytoskeleton-associated proteins are key determinants of early clone development provides new insight into the pathways that support cloning.

Population and Evolutionary Genetics: Molecular characterization and evolution of self- incompatibility genes in Arabidopsis thaliana: The case of the Sc haplotype, pp. 985-994 Kathleen G. Dwyer, Martin T. Berger, Rimsha Ahmed, Molly K. Hritzo, Amanda A. McCulloch, Michael J. Price, Nicholas J. Serniak,Leonard T. Walsh, June B. Nasrallah, and Mikhail E. Nasrallah

The switch from cross-pollination to self-pollination in Arabidospis thaliana was accompanied by inactivation of the two S-locus "self " recognition genes that determine self-incompatibility. This article reports a structural and functional analysis of an S haplotype belonging to the one group of A. thaliana S haplotypes that had remained largely uncharacterized. The results reveal the various ways the S locus was inactivated during or after the multiple independent switches to self-fertility that occurred in A. thaliana.

Population and Evolutionary Genetics: Detecting signatures of selection through haplotype differentiation among hierarchically structured populations, pp. 929-941 Mara Ins Fariello, Simon Boitard, Hugo Naya, Magali SanCristobal, and Bertrand Servin

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Genetics Society of America's Genetics journal highlights for March 2013

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