Gene flaws that raise the risk of breast cancer are surprisingly common in black women with the disease, according to the first comprehensive testing in this racial group. The study found that one-fifth of these women have BRCA mutations, a problem usually associated with women of Eastern European Jewish descent but recently highlighted by the plight of Angelina Jolie.

The study may help explain why black women have higher rates of breast cancer at young ages -- and a worse chance of survival.

Doctors say these patients should be offered genetic counseling and may want to consider more-frequent screening and prevention options, which can range from hormone-blocking pills to breast removal, as Jolie chose to do.

"We were

In this May 31, 2013, photo, breast cancer survivor Alicia Cook holds a letter from the University of Chicago informing her that test results showed she had the BRCA genetic defect linked to breast cancer, outside her home in Chicago. New research shows genetic breast cancer is more common in black women than previously thought. (AP Photo/M. Spencer Green)

Churpek gave results of the study Monday at an American Society of Clinical Oncology conference in Chicago. The researchers include Mary-Claire King, the University of Washington scientist who discovered the first breast cancer predisposition gene, BRCA1.

Jolie revealed a few weeks ago that she carries a defective BRCA1 gene, giving her up to an 87 percent risk of developing breast cancer and up to a 54 percent

Children of someone with a BRCA mutation have a 50 percent chance of inheriting it.

In the U.S., about 5 to 10 percent of breast cancers are thought to be due to bad BRCA genes. Among breast cancer patients, BRCA mutations are carried by 5 percent of whites and 12 percent of Eastern European (Ashkenazi) Jews. The rates in other groups are not as well known.

The study involved 249 black breast cancer patients from Chicago area hospitals. Many had breast cancer at a young age, and half had a family history of the disease.

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In breast cancer war, gene flaws common in black women

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