Scientists said Monday they had used a new-generation gene sequencing technique to select a viable embryo for in-vitro fertilisation (IVF) that yielded a healthy baby boy.

IVF, the process whereby a human egg is fertilised with sperm in the laboratory, is a hit-and-miss affair, with only about 30 percent of fertilised embryos resulting in pregnancy after implantation.

The reason for the high failure rate is not clear but genetic defects are the prime suspects, according to the authors of the paper presented Monday at a meeting in London of the European Society of Human Reproduction and Embryology (ESHRE).

The new method, known as next generation sequencing or NGS, uses updated technology to sequence an entire genome -- revealing inherited genetic disorders, chromosome abnormalities and mutations.

Study author Dagan Wells of the University of Oxford's NIHR Biomedical Research Centre said the new technology was "inherently cheaper" and yielded more genetic data than older methods.

It provides millions of fragments of DNA from a single cell which are then sequenced by a computer.

The method has started being used in genetic research and diagnostics, but not yet in embryo screening, according to Wells.

"Many of the embryos produced during infertility treatments have no chance of becoming a baby because they carry lethal genetic abnormalities," he said in a statement.

"Next generation sequencing improves our ability to detect these abnormalities and helps us identify the embryos with the best chances of producing a viable pregnancy."

Current methods of detecting embryonic gene deficiencies add over 2,000 (2,300 euros, $3,000) to a single IVF attempt, said Wells.

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New gene sequencing yields healthy baby

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