Oncodesign And the Laboratory for Neurobiology and Gene Therapy at The KU Leuven Enter into a Research Collaboration …

Posted: December 19, 2012 at 6:46 am

DIJON, France & LEUVEN, Belgium & PARIS--(BUSINESS WIRE)--

Regulatory News:

Oncodesign, a Drug Discovery company and oncology pharmacology service provider, and the Laboratory for Neurobiology and Gene Therapy (LNGT) at the Department of Neurosciences at the KU Leuven, an expert academic group exploring the roles of LRRK2 and -synuclein in Parkinsons disease headed by Professor Veerle Baekelandt, today announced that they have entered into a research collaboration to evaluate, with Ipsen (Euronext: IPN, ADR: IPSEY) (IPN.PA), Oncodesigns compounds in multiple pharmacology models for Parkinson's disease. The collaboration builds on Oncodesign's LRRK2 program with advanced Nanocyclix lead molecules that was partnered with Ipsen in January 2012.

Our partnership with Ipsen on the discovery of novel therapeutic agents in Parkinsons disease has advanced to a stage where we can use further in depth expertise and advanced pharmacology models to position our leads. We are very excited to collaborate with KU Leuven to advance our understanding of both our inhibitors and the LRRK2 target, said Jan Hoflack, Ph.D., Chief Scientific Officer and Head of Oncodesign's Discovery Activities.

This collaboration with Oncodesign is a perfect example of translational research in action, said Veerle Baekelandt, Ph.D., Principle Investigator of LNGT. Parkinsons disease has been the focus of our research for more than 10 years now. We are very pleased that Oncodesign has selected our lab as a partner for advancing their kinase program, she added.

We are thrilled that the expertise that our lab has built up from fundamental research on LRRK2 can be put to good use in evaluating and developing the biology aspects of compounds with therapeutic potential, said Jean-Marc Taymans, Ph.D., Group Leader of LNGT.

Ipsen and Oncodesign entered into a research collaboration last January for the development of new therapeutic agents against LRKK2 involved in Parkinson's disease, in line with our focus in neurology and movement disorders. We are delighted that our partnership with Oncodesign is moving forward as planned with the objective of developing therapeutics for Parkinsons disease patients. The Oncodesign collaboration with LNGT will greatly accelerate the progress of this research program stated Dr. Claude Bertrand, Executive Vice president, R&D, Chief Scientific Officer at Ipsen.

Under the terms of the agreement, Oncodesign and LNGT will closely collaborate to advance Oncodesign's Parkinsons disease program towards clinical development. LNGT will receive full financial support from Oncodesign for these activities.

About Oncodesign

Founded in 1995 and headed by Dr. Philippe Genne, Oncodesign is a pioneer in the preclinical assessment of anti-cancer therapies, a market that it is leading for many years. Oncodesigns mission consists of discovering effective anti-cancer therapies. Its scientific expertise in pharmacology, imaging and medicinal chemistry, in addition to strong project management skills, support the companys two strategic activities of experimentation and discovery, conducted in partnership with pharmaceutical and biotechnology companies.

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Oncodesign And the Laboratory for Neurobiology and Gene Therapy at The KU Leuven Enter into a Research Collaboration ...

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