Origin of spontaneous mutations – Video

Posted: February 10, 2013 at 7:45 am

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Video Link: https://www.youtube.com/watch?v=dPSmpSC-J8M



Origin of spontaneous mutations
For more information, log on to- shomusbiology.weebly.com Download the study materials here- shomusbiology.weebly.com In genetics, a mutation is a change of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal genetic element. Mutations result from unrepaired damage to DNA or to RNA genomes (typically caused by radiation or chemical mutagens), from errors in the process of replication, or from the insertion or deletion of segments of DNA by mobile genetic elements.[1][2][3] Mutations may or may not produce discernable changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes, including evolution, cancer, and the development of the immune system. Mutation can result in several different types of change in sequences; these can either have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely. One study on genetic variations between different species of Drosophila suggests that if a mutation changes a protein produced by a gene, the result is likely to be harmful, with an estimated 70 percent of amino acid polymorphisms having damaging effects, and the remainder being either neutral or weakly beneficial.[4] Due to the damaging effects that mutations can have on genes, organisms have mechanisms such as DNA repair to prevent mutations.[1]

By: Suman Bhattacharjee

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Origin of spontaneous mutations - Video

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