How does genetic testing influence anxiety, depression, and quality of life? A hereditary breast and ovarian cancer syndrome suspects trial – DocWire…
Posted: November 8, 2020 at 2:55 am
Background:Emotional distress associated with genetic testing for hereditary breast and ovarian cancer syndrome (HBOC) is reported to interfere with adherence to treatment and prophylactic measures and compromise quality of life.
Objectives:To determine levels of anxiety, depression, and quality of life in patients tested for pathogenic BRCA1/2 mutations and identify risk factors for the development of adverse psycho-emotional effects.
Methods:Cross-sectional observational trial involving 178 breast or ovarian cancer patients from a referral cancer hospital in Northeastern Brazil. Information was collected with the Hospital Anxiety and Depression Scale (HADS) and the World Health Organization (WHO) Quality of Life (QoL) questionnaire (WHOQOL-BREF).
Results:Patients suspected of HBOC had higher levels of anxiety than depression. The presence of (probably) pathogenic BRCA1/2 mutations did not affect levels of anxiety and depression. High schooling, history of psychiatric disease, and use of psychotropic drugs were directly associated with high anxiety. High schooling was too inversely associated with QoL as such a breast tumor. Anxiety and depression were directly correlated and both reduced significantly QoL.
Conclusion:Our results highlight the importance of psychological support and screening of risk factors for anxiety and depression and low QoL in HBOC patients at the time of testing.
Keywords:Anxiety; Breast cancer; Depression; Hereditary breast and ovarian carcinoma syndrome; Quality of life.
Read the original here:
How does genetic testing influence anxiety, depression, and quality of life? A hereditary breast and ovarian cancer syndrome suspects trial - DocWire...
- A New Price Tag for Breast Cancer Genetic Testing - Video [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Genetic testing technologies - Video [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Prostate Cancer Genetic testing - Video [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Genetic Testing - Video [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Genetic Testing - One of the Best Things to Happen to Me - littlemamauk - Video [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- BowelGene - genetic testing - Video [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Genetic Testing Fact Sheet - National Cancer Institute [Last Updated On: May 22nd, 2015] [Originally Added On: May 22nd, 2015]
- Genetic Testing - Genetics Home Reference [Last Updated On: May 22nd, 2015] [Originally Added On: May 22nd, 2015]
- FAQ About Genetic Testing - Genome.gov [Last Updated On: May 31st, 2015] [Originally Added On: May 31st, 2015]
- Regulation of Genetic Tests [Last Updated On: June 9th, 2015] [Originally Added On: June 9th, 2015]
- Types of Genetic Testing - Genetics Home Reference [Last Updated On: June 29th, 2015] [Originally Added On: June 29th, 2015]
- Genetic Testing: What You Should Know - FamilyDoctor.org [Last Updated On: July 3rd, 2015] [Originally Added On: July 3rd, 2015]
- Genetic Testing - BRCA1 & BRCA2 Mutations | Susan G. Komen [Last Updated On: July 6th, 2015] [Originally Added On: July 6th, 2015]
- What is genetic testing? - Genetics Home Reference [Last Updated On: July 6th, 2015] [Originally Added On: July 6th, 2015]
- Genomics |Genetic Testing [Last Updated On: August 24th, 2015] [Originally Added On: August 24th, 2015]
- What is genetic testing? - American Cancer Society [Last Updated On: August 24th, 2015] [Originally Added On: August 24th, 2015]
- Genetic testing - WebMD [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- Genetic Testing and Screening | Florida Hospital [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- Genetic Testing Toledo OH - DNA Diagnostics Center [Last Updated On: September 29th, 2015] [Originally Added On: September 29th, 2015]
- Genetics - Genetic testing and counselling - NHS Choices [Last Updated On: October 25th, 2015] [Originally Added On: October 25th, 2015]
- Genetic Testing Germantown MD - DNA Diagnostics Center [Last Updated On: February 18th, 2016] [Originally Added On: February 18th, 2016]
- GeneDx | Genetic Testing Company | The DNA Diagnostic Experts [Last Updated On: February 18th, 2016] [Originally Added On: February 18th, 2016]
- Genetic Testing - kidshealth.org [Last Updated On: February 24th, 2016] [Originally Added On: February 24th, 2016]
- BRCA1 and BRCA2: Cancer Risk and Genetic Testing [Last Updated On: February 29th, 2016] [Originally Added On: February 29th, 2016]
- Genetic Testing - Breastcancer.org - Breast Cancer ... [Last Updated On: April 4th, 2016] [Originally Added On: April 4th, 2016]
- Frequently Asked Questions About Genetic Testing - Genome.gov [Last Updated On: April 10th, 2016] [Originally Added On: April 10th, 2016]
- Pregnancy & Prenatal Testing: Genetic Testing for Inherited ... [Last Updated On: April 19th, 2016] [Originally Added On: April 19th, 2016]
- Genetic Testing | Family Caregiver Alliance [Last Updated On: April 19th, 2016] [Originally Added On: April 19th, 2016]
- Genetic Testing - American Medical Association [Last Updated On: April 19th, 2016] [Originally Added On: April 19th, 2016]
- Genetic Testing - Cancer Treatment | CTCA [Last Updated On: April 19th, 2016] [Originally Added On: April 19th, 2016]
- genome.gov - FAQ About Genetic Testing [Last Updated On: April 27th, 2016] [Originally Added On: April 27th, 2016]
- Family Cancer Genetics Program at UC San Diego Moores ... [Last Updated On: May 2nd, 2016] [Originally Added On: May 2nd, 2016]
- Genetic Testing - Benefits, costs, and risks of genetic testing [Last Updated On: May 13th, 2016] [Originally Added On: May 13th, 2016]
- Myriad Genetics | Healthcare Professionals | About Genetic ... [Last Updated On: May 13th, 2016] [Originally Added On: May 13th, 2016]
- Genetic Testing | Gluten-Free Society [Last Updated On: May 13th, 2016] [Originally Added On: May 13th, 2016]
- Genetic testing - Canadian Cancer Society [Last Updated On: May 13th, 2016] [Originally Added On: May 13th, 2016]
- Genetic Testing and Molecular Biomarkers [Last Updated On: May 13th, 2016] [Originally Added On: May 13th, 2016]
- genetic testing | Britannica.com [Last Updated On: May 13th, 2016] [Originally Added On: May 13th, 2016]
- Genetic Testing: Best Defense Against Breast Cancer? [Last Updated On: May 13th, 2016] [Originally Added On: May 13th, 2016]
- Genetic Testing | Issue List [Last Updated On: May 13th, 2016] [Originally Added On: May 13th, 2016]
- Jewish Genetics, Part 1: Jewish Populations (Ashkenazim ... [Last Updated On: June 19th, 2016] [Originally Added On: June 19th, 2016]
- What Is Genetic Testing -- Information About Genetic Testing [Last Updated On: June 23rd, 2016] [Originally Added On: June 23rd, 2016]
- Genetic Testing Report - genome.gov [Last Updated On: June 23rd, 2016] [Originally Added On: June 23rd, 2016]
- Good Laboratory Practices for Molecular Genetic Testing ... [Last Updated On: June 26th, 2016] [Originally Added On: June 26th, 2016]
- Genetics and Cancer | American Cancer Society [Last Updated On: July 18th, 2016] [Originally Added On: July 18th, 2016]
- Genetic testing - FSH Society [Last Updated On: September 22nd, 2016] [Originally Added On: September 22nd, 2016]
- Myriad Genetics | Patients & Families | Genetic Testing 101 [Last Updated On: September 22nd, 2016] [Originally Added On: September 22nd, 2016]
- BRCA1 and BRCA2: Cancer Risk and Genetic Testing Fact Sheet ... [Last Updated On: September 22nd, 2016] [Originally Added On: September 22nd, 2016]
- FAQ About Genetic Testing - National Human Genome Research ... [Last Updated On: September 22nd, 2016] [Originally Added On: September 22nd, 2016]
- Genetic testing - Wikipedia [Last Updated On: November 1st, 2016] [Originally Added On: November 1st, 2016]
- Genetic Testing for Cancer Risk | Cancer.Net [Last Updated On: November 25th, 2016] [Originally Added On: November 25th, 2016]
- Cancer Genetics Risk Assessment and Counseling (PDQ ... [Last Updated On: December 20th, 2016] [Originally Added On: December 20th, 2016]
- Patients Who Tested Positive For Genetic Mutations Fear Bias ... - NPR - NPR [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- Genetic Testing for the Healthy - Harvard Medical School (registration) [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- Genetic testing Overview - Mayo Clinic [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- The real reason why all women should get their DNA tested - Quartz [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- DNA insurance: Why genetic testing could revolutionise the industry - Verdict [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- Everything you need to know about the Government plan for genetic testing to treat cancer patients - BreakingNews.ie [Last Updated On: July 4th, 2017] [Originally Added On: July 4th, 2017]
- Greater access to genetic testing needed for cancer diagnosis and treatment - Cancer Research UK [Last Updated On: July 5th, 2017] [Originally Added On: July 5th, 2017]
- Chief medical officer calls for gene testing revolution - BBC News - BBC News [Last Updated On: July 5th, 2017] [Originally Added On: July 5th, 2017]
- Genetic Testing Facilities and Cost - Breastcancer.org [Last Updated On: July 5th, 2017] [Originally Added On: July 5th, 2017]
- Greater access to genetic testing needed for cancer diagnosis and ... - Medical Xpress [Last Updated On: July 7th, 2017] [Originally Added On: July 7th, 2017]
- Global Breast Cancer Predictive Genetic Testing Market Outlook 2022 - PR Newswire (press release) [Last Updated On: July 7th, 2017] [Originally Added On: July 7th, 2017]
- Invitae: Growth in Genetic Testing - Moneyshow.com (registration) [Last Updated On: July 7th, 2017] [Originally Added On: July 7th, 2017]
- Cystic Fibrosis Among Asians: Why Ethnicity-Based Genetic Testing is Obsolete - PLoS Blogs (blog) [Last Updated On: July 7th, 2017] [Originally Added On: July 7th, 2017]
- Hospital gets cardiac genetic test service created in memory of broadcaster's son - Belfast Telegraph [Last Updated On: July 8th, 2017] [Originally Added On: July 8th, 2017]
- David Frost cardiac genetic testing service opens - BBC News - BBC News [Last Updated On: July 8th, 2017] [Originally Added On: July 8th, 2017]
- UK's chief medical officer calls for gene testing revolution in cancer treatment - Daily Nation [Last Updated On: July 8th, 2017] [Originally Added On: July 8th, 2017]
- Konica Minolta buys US genetic test maker in $1B deal - BioPharma Dive [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Checking the cost of a genetic test - Chicago Tribune - Chicago Tribune [Last Updated On: July 11th, 2017] [Originally Added On: July 11th, 2017]
- Genomic Testing in Oncology: From Single Genes to Whole Genomes - Labiotech.eu (blog) [Last Updated On: July 12th, 2017] [Originally Added On: July 12th, 2017]
- Direct-To-Consumer Genetic Testing Can Be a Trip Down the Rabbit Hole - Newswise (press release) [Last Updated On: July 12th, 2017] [Originally Added On: July 12th, 2017]
- DNA Diagnostics Center brings four genetic testing options to retail - Drug Store News [Last Updated On: July 12th, 2017] [Originally Added On: July 12th, 2017]
- Jeans for Genes Day stall at Taree City Centre - Gloucester Advocate [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- She thought she was Irish until a DNA test opened a 100-year-old mystery - Chicago Tribune [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- Genetic testing: The new way to identify and train elite athletes? - USA TODAY High School Sports [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- Mail order genetic tests for health risks. How much do you want to ... - KOMO News [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- Genetic Testing: Finding the cause of your infertility ... [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- SF's Invitae to acquire two prenatal genetic screening firms - SFGate [Last Updated On: August 1st, 2017] [Originally Added On: August 1st, 2017]
- For Indian doctors, it's written in the genes not stars - Economic Times [Last Updated On: August 1st, 2017] [Originally Added On: August 1st, 2017]