The Preimplantation Genetic Testing Market Introduction

Preimplantation genetic testing is the process which is used prior to implantation to help identify genetic defects within embryos. This process helps to prevent certain genetic disorders that can transfer from parents to child. It involves screening single cells from embryos and performed during the process of in-vitro fertilization (IVF) prior to embryo transfer. Two main procedures are done for preimplantation genetic testing: preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS). The main application of PGD is to identify the presence of chromosomal translocations and single-gene disorders so that these embryos are not transferred and a healthy, disease free babys birth can take place. This process is also done to determine the sex of the embryo prior to the transfer into the uterus. Different techniques are used in preimplantation genetic testing such as Polymerase Chain Reaction (PCR), Next-Generation Sequencing (NGS), and Fluorescence in Situ Hybridization (FISH) for detection of disorders.

Preimplantation genetic screening (PGS) is applied technology from PGD and generally done for those people with recurrent pregnancy loss or infertility. Embryos are screened to determine the cause of miscarriage and implantation failure. Through this screening, abnormal embryos are identified so they are not transferred to the IVF cycle, to achieve successful pregnancy. PGS is done to screen an embryo for normal chromosome number or to identify loss or gain of chromosomal material.

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Preimplantation Genetic Testing Market Competitive Landscape

The global preimplantation genetic testing market is fragmented due to presence of major players. Key players operating in the global preimplantation genetic testing market include Agilent Technologies, Inc., Illumina, Inc., Abbott Laboratories, CooperSurgical, Inc., Thermo Fisher Scientific Inc., PerkinElmer Inc., Natera, Inc., Quest Diagnostics Incorporated, Genea Limited, and Vitrolife.

New product launch, partnerships, collaborations, and mergers & acquisitions are some of the key strategies adopted by these major players in developed as well as emerging economies. For instance, in January 2017, Agilent Technologies, Inc. and the Centre for Human Genetics, University of Leuven, and University Hospitals Leuven collaborated to investigate new solutions of preimplantation genetic testing.

Agilent Technologies, Inc.

Agilent Technologies, Inc. is headquartered in Santa Clara, CA, U.S. and operates in life sciences, diagnostics, and applied chemicals markets. The company was founded in 1999 and offers instruments, services, consumables, applications, and expertise to address the full range of scientific and laboratory management needs. Agilent Technologies, Inc. provides OnePGT Solution for research purposes which uses NGS technology.

Illumina, Inc.

Founded in 1998, Illumina, Inc.is based in San Diego, California, U.S. The company develops, manufactures, and markets life science tools and integrated systems for large-scale analysis of genetic variation and function. It has a global presence with over 7,300 employees globally. Illumina, Inc. offers various karyomapping products and solutions for PGD such as Infinium HumanKaryomap-12 DNA Analysis Kit and NextSeq 550 System.

The company has adopted a distribution partnership, collaboration, and alliances strategy for its PGD products. For instance, in October 2018, Illumina, Inc. and Vitrolife signed a distribution agreement. This agreement provided exclusive development, distribution, and commercialization rights to Vitrolife for Illumina, Incs. Preimplantation genetic testing business for IVF in the Americas and EMEA.

Abbott Laboratories

Established in 1888, Abbott Laboratories is headquartered in Chicago, Illinois, U.S. Abbott Laboratories is a major healthcare company which offers healthcare products and solutions such as diagnostics, medical devices, nutritionals, and branded generic medicines. The company serves more than 160 countries. Its PGD products and solutions comes under the genetics and genomics product division.

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CooperSurgical, Inc.

Founded in 1990, CooperSurgical, Inc. is based in Trumbull, Connecticut, U.S. The company has a diversified product portfolio of more than 600 products. It operates through two business segments: CooperSurgical medical devices and CooperSurgical Fertility & genomic solutions. The company offers PGT-A, PGT-M, and PGT-SR, which are major test solutions for PGD and PGS.

Preimplantation Genetic Testing Market- Dynamics

Rise in number of cases of child birth with genetic disorders and declining fertility rate globally to drive the global preimplantation genetic testing market

Increasing incidence of child birth with genetic disorders such as cystic fibrosis, Huntingtons disease, Down syndrome, and Turner syndrome due to chromosomal abnormalities, single gene defects, and other reasons is being seen. Rise in conditions of genetic disorders & abnormalities is attributed to growth of global preimplantation genetic testing market. For instance, as per CDC, around 6,000 babies are born with Down syndrome in the U.S. every year. According to the same report, between1979 to 2003, and the number of babies born with Down syndrome increased by about 30% in the U.S. Moreover, fertility rate among the current population is declining in recent years due to lifestyle changes which is propelling the need for PGS and hence the preimplantation genetic testing market is slated to grow globally.

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Higher risk of chromosomal abnormalities associated with advancing maternal age and more IVF procedures coupled with rise in number of fertility clinics, major growth drivers of the market

The risk of chromosomal abnormality increases with maternal age. A baby born to an older woman has higher risk of being born with some type of chromosomal abnormality & defect. According to an article published by Stanford Children's Health, U.S., the chance of having a child affected by Down syndrome rises from around 1 in 1,250 for a woman who conceives at the age of 25 years, to about 1 in 100 for a woman who conceives at the age of 40 years. Also, rise in number of fertility clinics and IVF procedures worldwide is propelling the growth of the global preimplantation genetic testing market.

Higher procedural cost and certain regulatory norms restraining the market growth

Factors such as higher cost associated with PGD & PGS and certain strict regulatory norms are likely to hamper the growth of the global preimplantation genetic testing market. Preimplantation genetic testing is a complex procedure that entails a lot of laboratory work; hence, the cost can be significant and high for the entire procedure. Also, non-medical use of PGD and PGS raises the government regulatory norms in certain countries. These strict rules are likely to hamper the growth of the global preimplantation genetic testing market.

North America preimplantation genetic testing Market Major Market

North America dominated the global preimplantation genetic testing market in 2018. It is projected to maintain its position during the forecast period. Higher infertility rate, more number of IVF cycles, presence of major players in the region, and adoption of highly advanced technologies for genomics are some of the major factors responsible for the dominance of this region in the global market. For instance, according to CDC data, between 2011 to 2015, 6.7% of married women aged 15-44 years were facing infertility problems in the U.S.

Preimplantation Genetic Testing Market Segmentation

The global market can be segmented on the basis of: Procedure Type Product & services Technology Application End-user Region

Preimplantation Genetic Testing Market Segmentation By Procedure Type

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Based on procedure type, the market can be segmented into: Preimplantation Genetic Diagnosis Preimplantation Genetic Screening

Preimplantation Genetic Testing Market Segmentation By Product & Services

In terms of product & services, the market can be divided into: Reagents & Consumables Instruments Softwares & Services

Preimplantation Genetic Testing Market Segmentation By Technology

On the basis of technology, the market can be classified into: Polymerase Chain Reaction(PCR) Next-Generation Sequencing(NGS) Fluorescence in Situ Hybridization(FISH) Others

Preimplantation Genetic Testing Market Segmentation By Application

Depending on application, the market can be segmented into: Aneuploidy Single Gene Disorders Structural Chromosomal Abnormalities Gender Identification HLA Typing Others

Structural Chromosomal Abnormalities segment is further sub segmented into- Inversions Translocations Deletions Duplications

Preimplantation Genetic Testing Market Segmentation By End-user

Based on end-user, the market can be divided into: Hospitals, Diagnostic Labs & Service Providers Maternity & Fertility Centers Research Laboratories & Academic Institutes

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Link:
Preimplantation Genetic Testing Market Opportunity Analysis and Industry Forecast up to 2027 - Rapid News Network

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