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In 2020, for the first time, medication abortions accounted for more than half of all abortions in the United States. Thats after the pandemic led the FDA to lift a restriction that had required doctors to dispense Mifepristone, one of the two pills used to induce abortion, in person.

The pills are approved to terminate a pregnancy that is up to 10 weeks along. The pills can be taken at home and they cause similar symptoms to spontaneous miscarriage.

If the U.S. Supreme Court overturns Roe v. Wade, which is expected this month, abortion will likely become illegal in about half of the states. But abortion pills could wind up in a legal gray area approved at the federal level by the FDA, but subject to state-level abortion bans.

And because they will remain available in neighboring states that allow abortion and through online suppliers, they offer a potential workaround for anyone who wants an abortion but doesnt have the resources to travel to a state where it is legal. In Texas, for example, the number of people ordering abortion pills from an online telemedicine service tripled after state legislators passed an abortion ban in 2021.

States are already moving to limit access to medication abortion, and the FDA has sent warning letters to some of the online telemedicine companies that have tried to develop workarounds to state-level regulations.

In Oregon, a state with no restrictions on abortion, the pills are available at a wide variety of hospitals and clinics, or through telehealth appointments. Medication abortions account for about 70% of those provided by the two Planned Parenthood affiliates in Oregon, which are responsible for more than half of all abortions statewide.

To put together this guide, we spoke with two experienced obstetrician-gynecologists, the type of doctor who typically provides prenatal care and delivers babies, about abortion pills.

Oregon Health & Science Universitys Dr. Maureen Baldwin has been part of clinical trials of telemedicine abortion where a medical provider meets with and evaluates a patient via videoconference before and during the pandemic.

Dr. Paula Bednarek is an associate professor of obstetrics and gynecology at OHSU and the medical director of Planned Parenthood Columbia-Willamette.

Both doctors are supporters of abortion rights.

Using pills to end an unwanted pregnancy, or to manage a miscarriage, is known as a medication abortion. The most effective method uses two drugs: Mifepristone and Misoprostol.

Mifepristone, originally known as RU-486, is taken first. It blocks progesterone, a hormone thats needed to continue a pregnancy.

The second medication, Misoprostol, is generally taken at least 24 hours later. It starts contractions and prompts the body to expel the pregnancy. (This medication is also sometimes used to induce labor at the end of a full-term pregnancy.)

Each medication has been used individually to induce abortion, but they are most effective when taken in combination at nine weeks or less. When a pregnancy is less than seven weeks along, there is a less than 1% chance of a pregnancy continuing after following the two-step protocol, according to Baldwins research. After seven weeks, the chance of a pregnancy continuing rises incrementally. In the tenth week of pregnancy, the chance of a pregnancy continuing is about 8%.

Medication abortion is used to end pregnancies that are less than 10 weeks, or 70 days along, counted from the last day of the most recent period.

Its also an option that can help manage pregnancy loss when the process of miscarrying has started but hasnt completed naturally.

Medication abortion can be used at any point after getting a positive pregnancy test, around 4 weeks.

In a clinical or hospital setting under medical supervision, medication abortion can sometimes be used to end a pregnancy that is further than 10 weeks along. There is a higher risk of significant and dangerous bleeding after 10 weeks.

There are relatively few risk factors that make the procedure unsafe for people seeking an abortion in early pregnancy. Medication abortion is not used for people with a known allergy to Mifepristone, certain bleeding disorders, suspected ectopic pregnancy, chronic adrenal failure, or people on chronic steroid therapy. It is also not used when someone has gotten pregnant with an IUD in place.

Yes, but only if those people are physically located in Oregon for their appointment or telehealth appointment.

That is part of how all telemedicine is regulated. Providers have to be licensed in the state where the patient is located and follow the laws of the state where the patient is located.

The patient also needs an Oregon mailing address if they plan to receive pills by mail.

In the United States, getting Mifepristone requires a consultation and prescription from a doctor or health professional.

In Oregon, that can happen in person, or through telemedicine over the phone or online.

First, a doctor evaluates the patient to confirm how far along they are in pregnancy and to determine if there are any reasons the procedure might not be safe for a particular patient.

Baldwin says in most cases, an ultrasound isnt necessary.

We know from a lot of research that patients who have been recording their periods are very accurate in knowing how far along they are, she said.

Patients can pick up the medication in person at a doctors office or Planned Parenthood clinic, or have the medication mailed to them. Its not yet available in retail pharmacies.

After taking the second medication, Misoprostol, the patient may feel nauseous and throw up. They will have a lot of bleeding and cramping.

The length of time it takes to pass the pregnancy tissue can vary. It can be a very fast process, 90 minutes overall. Or, the bleeding and pain can last a few days and come and go in waves.

Standard care includes a follow-up evaluation to ensure the pregnancy tissue has all been passed.

At OHSU, for example, there are three options: a self-evaluation and home pregnancy test a few weeks afterward, an ultrasound in a clinic following the abortion, or blood tests for pregnancy hormone levels before and after the procedure.

Some people really want to have a visual, Baldwin said. In fact, we know that a lot of people come to emergency departments after a medication abortion for reassurance actually that the pregnancy has completed, she said.

Abortions are available at all Planned Parenthood health centers, at many private obstetrics and gynecology practices and in the Kaiser Permanente, OHSU, and Legacy Health systems.

Providence Health Services provides medical and surgical abortions for patients experiencing miscarriage, pregnancy loss, or a life-threatening emergency, along with resources to cope with the loss. Providence will not provide induced or elective abortions. Providence patients who are Oregon Health Plan members can access abortion through a different provider, regardless of the reason, by calling Oregon Health Plan client services at 1-800-273-0557.

Neither the Indian Health Service nor Veterans Affairs provide abortions, due to the Hyde Amendment, a law that restricts federal funding for abortion.

Federally Qualified Health Centers. which provide primary care to low-income, uninsured, rural and historically disadvantaged populations, also do not provide abortions, due to congressional restrictions. They do provide referral services for abortions and other options for their patients.

All of these services will continue to remain legal in Oregon unless state legislators change the laws here, which seems unlikely given the political make-up of the state government right now.

Boxes of the drug mifepristone line a shelf at the West Alabama Women's Center in Tuscaloosa, Ala., on Wednesday, March 16, 2022. The drug is one of two used together in "medication abortions." According to Planned Parenthood, mifepristone blocks progesterone, stopping a pregnancy from progressing.

Allen G. Breed / AP

Mifepristone was invented in France and was first approved by the FDA for abortion, in combination with Misoprostol, in 2000.

Misoprostol is FDA approved to treat ulcers. Its used for abortions and, at a lower dose, for labor induction. The medications uses in gynecology are included in the labeling for Mifepristone and are considered safe by the American College of Obstetricians and Gynecologists.

The FDA regulates Mifepristone more tightly than most drugs and collects more complete safety data on it. Since 2011, the FDA has added what is known as a Risk Evaluation and Mitigation Strategy (REMS) to the drug. Doctors who prescribe it have to follow some special record-keeping practices and report any cases of complications, and patients who take it have to sign a form saying theyve been informed of the risks.

In December 2021, the FDA rolled back some prior restrictions on the drug. As a result, by the end of 2022, it may be available in some retail pharmacies.

Some may prefer being able to have an abortion in the comfort of their home. Some people may feel it is less invasive, or more natural, than a surgical procedure. Medication abortion via telehealth may be easier for those who live in parts of the state without a nearby abortion provider.

It is also easier to book an appointment for a medication abortion, according to Bednarek. Surgical abortions are only available in some Planned Parenthood locations in Oregon, on specific days of the week.

There is a similar safety profile for medication abortion and surgical abortion for early pregnancy. Surgical abortions do have advantages. They are more predictable and over more quickly, with less bleeding.

If somebody wants to have sedation and be asleep and have it be less pain and be over with more quickly and not have to experience the process of the abortion, that is an option with surgical abortion, Baldwin said.

A persons pain level can vary based on their prior experience with pregnancy, birth, or pregnancy loss. It can also vary based on how far along a pregnancy is. For some people, the cramping may be as painful as labor contractions. For others, it is more like bad period cramping.

Ibuprofen, a heating pad, and a warm bath or shower can be effective in helping patients manage the most significant cramping, which typically lasts in the 4-6 hour range.

People should not take aspirin. It can cause them to bleed more.

Some patients may want stronger pain medication.

We talk with patients and we provide whatever pain medicine they feel that they need, which might include a prescription for a narcotic pain medicine, but most often over-the-counter medicines are really effective, said Bednarek.

There can be a physical and emotional recovery process afterward, that can vary with the circumstances that surround a persons choice to get abortion care. Some feel relief. Others feel sadness. Many feel lots of things all at once.

Abortions, including medication abortions, are generally safe procedures.

In 2018, the National Academies of Sciences, Engineering, and Medicine convened an expert committee to review the practice of abortion in the United States. The committees final report reads: Legal abortionswhether by medication, aspiration, D&E, or inductionare safe. Serious complications are rare and occur far less frequently than during childbirth. Safety is enhanced when the abortion is performed as early in pregnancy as possible.

(Aspiration is a procedure that involves suctioning out pregnancy tissue. The term D&E stands for dilation and evacuation, and involves dilating the cervix and surgically removing pregnancy tissue.)

During a minority of medication abortions, less than 5%, complications arise.

The most common complication is that it doesnt work. In that case, a follow-up surgical abortion is required.

Rarely, in less than 1% of cases, medication abortions can cause more serious and even fatal complications. These include prolonged heavy bleeding, infections and sepsis, and ruptured ectopic pregnancies.

In an extremely small number of cases, medication abortion has been linked to infection with clostridum sordellii, a particularly dangerous type of bacterial infection thats also a rare complication of miscarriage and childbirth. It can trigger toxic shock syndrome and can be hard to diagnose because patients may have an infection without a fever.

According to the Mifepristone label, people should contact their provider or seek help if they have:

In the US, medication abortion has an associated mortality rate of less than 1 in 100,000, according to the Kaiser Family Foundation. The mortality rate associated with giving birth is 23.8 deaths per 100,000 live births, according to the CDC. In the United States, there are more deaths annually due to accidental Tylenol overdoses than from all types of abortion.

Thats also safe, according to research conducted during the pandemic.

A study published in 2021 looked at more than 50,000 patients in the United Kingdom who received medication abortions. One group had received the pills at an in-person clinic visit that included an ultrasound. The other group received the pills by mail, after a telehealth consultation.

The study found no evidence of worse outcomes linked to telemedicine abortion. It found telemedicine abortion had significant advantages. Patients had shorter waiting times and there was a 40% increase in the number of abortions provided at 6 weeks gestation or less.

The FDA warns against purchasing Mifepristone and Misoprostol outside of the American medical system.

For someone living in Oregon, often. Medication abortion is covered by the Oregon Health Plan and by many private insurance plans. It is not covered for tribal members who get care through the Indian Health Service, nor to veterans who get care through the VA, due to the Hyde Amendment.

It is not covered for people on a Providence Health Plan.

If everyone in the United States has access to abortion pills and quality information on how to use them, and when to seek help, it could reduce some of the medical risks associated with a return to illegal abortions. In short, the pills may make illegal or self-managed abortions safer than they were in 1973.

In terms of what options are for self-managed abortions were a world away from where we were, Bednarek said.

There is some evidence, for example, that the availability of Misoprostol in some Caribbean, Latin American, and African countries has reduced maternal mortality from unsafe abortions.

Self-managed abortion may carry significant legal risks. In some states with laws that oppose abortion, prosecutors have filed homicide charges against people who tried to end their pregnancies outside the medical system. And in Pennsylvania, a mother who bought abortion pills online for her daughter was sentenced to 18 months in prison for violating state abortion regulations.

Bednarek says in states where Planned Parenthood cannot legally provide medication abortion, it can provide information to anyone who has obtained pills outside the regular health care system.

If patients call us with questions and need help, we are here to support them at any point through their process, she said.

Anyone who has started the process outside the health care system and is experiencing complications or warning signs can also get help at Planned Parenthood.

We can still do an ultrasound, we can help them with additional medications or an aspiration procedure if thats part of whats needed, we can evaluate them for ectopic pregnancy, Bednarek said. Patients should not feel worried that they will be judged or turned in or something like that.

See the rest here:
Medication abortions are easy to access in Oregon, but how do they work? - Oregon Public Broadcasting

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