Why Can Some Medicines Increase The Risk Of Osteoporosis? – Nation World News

Posted: August 20, 2022 at 1:50 am

To find out whether a patient may be at risk of osteoporosis, there is a mechanism that allows for screening: bone densitometry.

Rheumatologists indicate that in osteoporosis, in addition to the loss of mass, the microscopic architecture of the bone is affected. Photo: Shutterstock.

Within the framework of Reuma Expo 2022, experts warn that a variety of Medicine Focusing on getting relief from illnesses or other types of conditions in the body that can have an impact on the development of osteoporosis, In this regard, Dr. Noemi Varela Rosario and Dr. Ramn Ortega Coln, board members of the Puerto Rican Foundation for Rheumatic Diseases, called on patients to consult with their doctors about the effects and risks of certain medications.

In osteoporosis bone resorption occurs, so mass is lost he is And the body is unable to repair it in the same way. In addition to this loss of mass, the bone microarchitecture is affected, which gradually weakens the structure, producing brittleness and potential future fractures in patients.

Dr. Noemi said, We usually see patients who have back pain and buy medication or some who constantly take antacids like omeprazole and pantoprazole without realizing that it may add other risks.

In that sense, Dr. Ortega explained that when we Medicine By which the acid in the stomach dries up, we can create an atrophy of the gastric mucosa and prevent the absorption of minerals that the bone needs, creating a greater risk osteoporosis,

Regarding this condition, rheumatologists also indicated that, as in the case of vertebrae, fractures may be silent, with the patient losing the vertebral mass as well as its height, in addition to falling over the years.

According to the Spanish Foundation of Rheumatology, the drug best known for its effects on bone is glucocorticoid, but many bone metabolisms can also be altered. Medicine,

Various studies indicate that osteoporosis Another major cause of this is glucocorticoid-induced osteoporosisPostmenopausal, and its first cause osteoporosis Secondary. It is also considered a model of osteoporosis drug induced.

It is noteworthy that vertebral fractures are the most frequent consequence of chronic glucocorticoid administration, however, the intensity of the loss of mineral density he is It depends on the daily dose, timing of administration and cumulative dose.

However, according to the Rheumatology Foundation, the following Medicine May also play a role in the development of this condition: L-thyroxine, heparin, antiepileptics, neuroleptics, chemotherapy, aromatase inhibitors, GnRH, methotrexate, cyclosporine A, proton pump inhibitors, antidepressants: tricyclic and selective inhibitors of serotonin, lithium, loop. diuretics, and thiazolidinediones.

In the case of cancer patients, the risk of suffering osteoporosis This is more due to the effects of chemotherapy, radiotherapy, hormonal treatments and non-hormonal treatments.

Gonadotropin-releasing hormone (GnRH) analogs have an antigonadotropic effect in men and women. They are used for the treatment of prostate cancer and endometriosis and have a rapid increase in resorption after 6-12 months of treatment. he isMainly trabecular bone loss and increased risk of fracture.

The American Society of Oncology recommends that fracture risk assessment and dual-source X-ray densitometry be performed on all patients with hypogonadism or starting treatment with aromatase inhibitors.

Screening Test: Bone Densitometry

To find out if a patient may be at risk of osteoporosis or even suffer from it, rheumatologists have a mechanism that allows screening and seeing how fragile it is; Densitometry is he is,

In this regard, Dr. Ortega explained that this test is usually done around menopause in the case of women, because estrogens keep bone healthy and strong, but they decrease and estrogen is needed to maintain health. is important. he is,

He also indicated that densitometry he is This is a simple way to measure bone mass in the vertebrae and hip, in the neck of the femur, and in the total area of the hip.

Once the patient learns he has a mass, he is given a follow-up he is Less, it is a preventive treatment on a case by case basis. There are reasons where the patient may have osteoporosis Because she has certain diseases since childhood that weaken her bones, who have intestinal inflammation, who has malnutrition, who has alcohol, who smokes or is extremely thin. Different causes should be investigated in each patient who develops osteoporosisEmphasised the rheumatologist.

After Densitometry Test he isThe expert indicated that there are certain parameters established by the World Health Organization to provide preventive treatment to the patient, according to their risk factors, whether they are lifestyle habits or family history.

We have many ways to deliver preventive treatment. There are Medicine which prevents the loss of mass he isand these are Medicine Most commonly used: alendronate and risedronate. there are Medicine that if we look at a relatively young patient who has lost mass he isStimulates bone formation and helps the patient with A. must be used early to prevent brittleness Quite serious he added.

View the full program here.

See more here:
Why Can Some Medicines Increase The Risk Of Osteoporosis? - Nation World News

Related Posts

Comments are closed.

Archives