Growth Hormone Deficiency Following Complicated Mild Traumatic Brain Injury – Lexology (registration)
Posted: April 9, 2017 at 8:46 pm
Traumatic brain injury (TBI) is considered the main cause of hypopituitarism in adults and growth hormone (GH) deficiency is the most common pituitary deficit associated with TBI.
According to Cedars-Sinai, even after we stop growing, adults need growth hormone. Growth hormone plays a role in healthy muscle, how our bodies collect fat (especially around the stomach area), the ratio of high density to low density lipoproteins in cholesterol levels, and bone density. In addition, growth hormone is needed for normal brain function.
A recent study aimed to assess pituitary function and GH deficiency in adult patients at different time durations following complicated mild TBI, according to the Glasgow Coma Scale (GCS). The study also aimed to evaluate whether mild TBI patients with GH deficiency had developed alterations in the glycolipid profile.
Forty-eight patients (34 men and 14 women) with complicated mild TBI were included in the study. Twenty-three patients were evaluated at 1 year (Group A), and 25 patients at 5 years or longer after the injury (Group B). All patients underwent basal hormonal evaluation for pituitary function. GH deficiency was investigated by the combined test (GH releasing hormone + arginine). The glycolipid profile was also evaluated.
Researchers report that GH deficiency occurred in 8/23 patients (34.7 percent) of Group A and in 12/25 patients (48 percent) of Group B. In addition, two patients, one in each group, showed evidence of central hypothyroidism. Patients examined one-year or several years after complicated mild TBI had a similarly high occurrence of isolated GH deficiency, which was associated with visceral adiposity and metabolic alterations.
These findings suggest that patients with complicated mild TBI should be evaluated for GH deficiency even if several years have passed since the underlying trauma.
- Frequently asked HYPOPITUITARY questions....and their ... [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Hypopituitarism: Causes, Symptoms, & Treatment [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Hypopituitarism | University of Maryland Medical Center [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Hypopituitarism - Wikipedia, the free encyclopedia [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Hypopituitary: Learn Hypopituitarism Causes and Symptoms [Last Updated On: May 27th, 2015] [Originally Added On: May 27th, 2015]
- Hypopituitarism in Children: Get Information About Symptoms [Last Updated On: May 27th, 2015] [Originally Added On: May 27th, 2015]
- Pituitary Network Association - Disorders - Hypopituitarism [Last Updated On: May 30th, 2015] [Originally Added On: May 30th, 2015]
- Hypopituitarism and Hypopituitarism Resources - What is ... [Last Updated On: July 3rd, 2015] [Originally Added On: July 3rd, 2015]
- Hypopituitarism - Symptoms, Diagnosis, Treatment and ... [Last Updated On: July 3rd, 2015] [Originally Added On: July 3rd, 2015]
- Hypopituitarism | Johns Hopkins Medicine Health Library [Last Updated On: July 8th, 2015] [Originally Added On: July 8th, 2015]
- Hypopituitarism Symptoms and Treatment | Hormone Health ... [Last Updated On: August 17th, 2015] [Originally Added On: August 17th, 2015]
- Clinically Non-Functioning Pituitary Adenomas | UCLA ... [Last Updated On: February 1st, 2016] [Originally Added On: February 1st, 2016]
- Hypopituitarism | The Pituitary Foundation [Last Updated On: February 19th, 2016] [Originally Added On: February 19th, 2016]
- Hypopituitarism: Check Your Symptoms and Signs [Last Updated On: February 27th, 2016] [Originally Added On: February 27th, 2016]
- Hypopituitarism - Symptoms, Diagnosis and Treatment [Last Updated On: February 27th, 2016] [Originally Added On: February 27th, 2016]
- Hypopituitarism Hypopituitarism Hypopituitarism [Last Updated On: February 27th, 2016] [Originally Added On: February 27th, 2016]
- What Is Hypopituitarism (Dwarfism)? - Child Growth and ... [Last Updated On: March 3rd, 2016] [Originally Added On: March 3rd, 2016]
- Hypopituitarism | Boston Children's Hospital [Last Updated On: March 4th, 2016] [Originally Added On: March 4th, 2016]
- Symptoms and causes - Hypopituitarism - Mayo Clinic [Last Updated On: May 8th, 2016] [Originally Added On: May 8th, 2016]
- Hypopituitarism - RightDiagnosis.com [Last Updated On: May 24th, 2016] [Originally Added On: May 24th, 2016]
- Hypopituitarism - Hormonal and Metabolic Disorders - Merck ... [Last Updated On: June 19th, 2016] [Originally Added On: June 19th, 2016]
- Hypopituitarism. [Last Updated On: August 20th, 2016] [Originally Added On: August 20th, 2016]
- Symptoms of Hypopituitarism - RightDiagnosis.com [Last Updated On: August 31st, 2016] [Originally Added On: August 31st, 2016]
- Hypopituitary: Pituitary Gland Disorder Causes & Treatments [Last Updated On: August 31st, 2016] [Originally Added On: August 31st, 2016]
- Panhypopituitarism: Background, Pathophysiology, Epidemiology [Last Updated On: August 31st, 2016] [Originally Added On: August 31st, 2016]
- Hypopituitarism Hypopituitarism [Last Updated On: August 31st, 2016] [Originally Added On: August 31st, 2016]
- Hypopituitarism - Wikipedia [Last Updated On: October 21st, 2016] [Originally Added On: October 21st, 2016]
- Suzy's story - hypopituitarism | The Pituitary Foundation [Last Updated On: November 17th, 2016] [Originally Added On: November 17th, 2016]
- Hypopituitarism (Panhypopituitarism): Background ... [Last Updated On: November 28th, 2016] [Originally Added On: November 28th, 2016]
- Hypopituitarism-Panhypopituitarism [Last Updated On: November 29th, 2016] [Originally Added On: November 29th, 2016]
- Hypopituitarism in Children Causes, Symptoms, Treatment ... [Last Updated On: December 7th, 2016] [Originally Added On: December 7th, 2016]
- What is Hypopituitarism, Pituitary Insufficiency | Hormone.org [Last Updated On: December 7th, 2016] [Originally Added On: December 7th, 2016]
- Evaluation of ICD-10 algorithms to identify hypopituitary patients in the Danish National Patient Registry - Dove Medical Press [Last Updated On: February 10th, 2017] [Originally Added On: February 10th, 2017]
- Yeovil Hospital sorry for charges of over 400 wrongly sent to stressed mum of disabled girl - Somerset Live [Last Updated On: February 15th, 2017] [Originally Added On: February 15th, 2017]
- Hyperprolactinaemia: diagnosis and management - GP online [Last Updated On: February 16th, 2017] [Originally Added On: February 16th, 2017]
- Hopsital apologises to mother for parking fines caused by faulty system - View News [Last Updated On: February 24th, 2017] [Originally Added On: February 24th, 2017]
- Fundraiser Sunday to benefit Creek infant - Daily Union [Last Updated On: February 24th, 2017] [Originally Added On: February 24th, 2017]
- New autoimmune disease triggered by thymomas - Science Daily [Last Updated On: March 2nd, 2017] [Originally Added On: March 2nd, 2017]
- Hypopituitarism - familydoctor.org [Last Updated On: March 8th, 2017] [Originally Added On: March 8th, 2017]
- Joanna Lane:: Brain injury can cause treatable pituitary disorder - Madison.com [Last Updated On: March 10th, 2017] [Originally Added On: March 10th, 2017]
- Hypopituatarism - a lesser-known effect of traumatic brain injury - Lexology (registration) [Last Updated On: March 10th, 2017] [Originally Added On: March 10th, 2017]
- Cold Springs FCCLA brings home state awards - Cullman Times Online [Last Updated On: March 18th, 2017] [Originally Added On: March 18th, 2017]
- Thymomas Trigger Newly Described Autoimmune Endocrine Disease - Oncology Nurse Advisor [Last Updated On: March 21st, 2017] [Originally Added On: March 21st, 2017]
- Fighting Cancer With Fundraising: Meet Milwaukee's Dr. John Hanson - Milwaukee Magazine [Last Updated On: March 24th, 2017] [Originally Added On: March 24th, 2017]
- Penn Medicine Researchers Receive Distinguished Investigator Awards - Newswise (press release) [Last Updated On: March 28th, 2017] [Originally Added On: March 28th, 2017]
- Hypopituitarism Symptoms, Causes & 8 Natural Remedies [Last Updated On: March 31st, 2017] [Originally Added On: March 31st, 2017]
- Shannen's illnesslife-threatening or not? - Trinidad & Tobago Express [Last Updated On: April 18th, 2017] [Originally Added On: April 18th, 2017]
- Hypopituitarism. Medical information about Hypopituitarism ... [Last Updated On: May 3rd, 2017] [Originally Added On: May 3rd, 2017]
- FDA Grants BAVENCIO (avelumab) Approval for a Common Type of Advanced Bladder Cancer - PR Newswire (press release) [Last Updated On: May 10th, 2017] [Originally Added On: May 10th, 2017]
- Clinton child battles rare genetic disorder - Utica Observer Dispatch [Last Updated On: May 22nd, 2017] [Originally Added On: May 22nd, 2017]
- Treatment of hypopituitarism - uptodate.com [Last Updated On: May 22nd, 2017] [Originally Added On: May 22nd, 2017]
- Male Hypogonadism Market Deep Research Study with Forecast by 2025 - Digital Journal [Last Updated On: July 12th, 2017] [Originally Added On: July 12th, 2017]
- Hormone Replacement Therapy Market: Global Industry Analysis, Size, Share, Growth, Trends, and Forecasts 2016 ... - Digital Journal [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- Hormone Replacement Therapy Market: Industry Players to Show High Growth Rate by 2024 - Monotone Critic [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- What Is Hypopituitarism (Dwarfism)? - Verywell [Last Updated On: August 4th, 2017] [Originally Added On: August 4th, 2017]
- The Pituitary Society | Glossary of Terms Related to ... [Last Updated On: August 14th, 2017] [Originally Added On: August 14th, 2017]
- Hypopituitarism | You and Your Hormones from the Society ... [Last Updated On: August 21st, 2017] [Originally Added On: August 21st, 2017]
- Severe hyponatremia due to hypopituitarism with adrenal ... [Last Updated On: September 20th, 2017] [Originally Added On: September 20th, 2017]
- Pituitary Disorders - labtestsonline.org [Last Updated On: January 7th, 2018] [Originally Added On: January 7th, 2018]
- Prevalence of Hypopituitarism in Veterans 42% A NEW ... [Last Updated On: February 7th, 2018] [Originally Added On: February 7th, 2018]
- LABOKLIN (UK)| Genetic Diseases | Dogs| Dwarfism ... [Last Updated On: February 8th, 2018] [Originally Added On: February 8th, 2018]
- Hypopituitarism: Causes, Symptoms, and Treatment [Last Updated On: February 28th, 2018] [Originally Added On: February 28th, 2018]
- Hypopituitarism - Symptoms and causes - Mayo Clinic [Last Updated On: February 28th, 2018] [Originally Added On: February 28th, 2018]
- Generalized Hypopituitarism - Endocrine and Metabolic ... [Last Updated On: March 5th, 2018] [Originally Added On: March 5th, 2018]
- Hypopituitary: Hypopituitarism Causes, Symptoms & Treatment [Last Updated On: March 26th, 2018] [Originally Added On: March 26th, 2018]
- Hypopituitarism - Symptoms, Causes, Diagnosis and Treatment - Prime Health Channel [Last Updated On: April 8th, 2018] [Originally Added On: April 8th, 2018]
- Hypopituitarism | Hormone Health Network [Last Updated On: April 24th, 2018] [Originally Added On: April 24th, 2018]
- Hypopituitarism in Kids: Definition, Symptoms, Treatment [Last Updated On: May 11th, 2018] [Originally Added On: May 11th, 2018]
- Hypopituitarism - Diagnosis and treatment - Mayo Clinic [Last Updated On: June 4th, 2018] [Originally Added On: June 4th, 2018]
- What is hypopituitarism? | The Pituitary Foundation [Last Updated On: July 12th, 2018] [Originally Added On: July 12th, 2018]
- Hypopituitarism in Children | Children's Hospital of Philadelphia [Last Updated On: July 12th, 2018] [Originally Added On: July 12th, 2018]
- OMIM Entry - # 146510 - PALLISTER-HALL SYNDROME; PHS [Last Updated On: July 26th, 2018] [Originally Added On: July 26th, 2018]
- Hypopituitarism | Lifespan [Last Updated On: August 23rd, 2018] [Originally Added On: August 23rd, 2018]
- Panhypopituitarism: Practice Essentials, Pathophysiology ... [Last Updated On: August 23rd, 2018] [Originally Added On: August 23rd, 2018]
- Hypopituitarism | You and Your Hormones from the Society for ... [Last Updated On: August 23rd, 2018] [Originally Added On: August 23rd, 2018]
- Hypopituitarism Treatment & Causes | Lurie Children's [Last Updated On: October 3rd, 2018] [Originally Added On: October 3rd, 2018]
- Hypopituitarism Disease Reference Guide - Drugs.com [Last Updated On: October 3rd, 2018] [Originally Added On: October 3rd, 2018]
- Hypopituitarism | UCLA Health [Last Updated On: October 7th, 2018] [Originally Added On: October 7th, 2018]
- Steroid Replacement Doses for Hypopituitary Patients ... [Last Updated On: January 24th, 2019] [Originally Added On: January 24th, 2019]
- Non-Functioning Tumors (Endocrine-Inactive Tumors ... [Last Updated On: January 29th, 2019] [Originally Added On: January 29th, 2019]