There is No Limit to Human Life Extension – Futurism
Posted: February 8, 2017 at 9:44 pm
The Strehler-Mildvan Correlation
The scientific team of biotech company Gero recently published a study in the Journal of Theoretical Biology that debunks a long-held misconception regarding two parameters of the Gompertz mortality law a mortality modelthat represents human death as the sumof two components that exponentially increases with age. The Gero team studied whats called the Strehler-Mildvan (SM) correlation and found no real biological reasoning behind it, despite having been held true for more than a half a century now.
The SM correlation, derived from the Strehler-Mildvan general theory of aging and mortality, is a mechanism-based explanation of Gompertz law. Specifically, the SM correlation uses two Gompertz coefficients called the Mortality Rate Doubling Time (MRDT) and Initial Mortality Rate (IMR). Popularized in the 1960s in a paper published in Science, the SM correlation suggests that reducing mortality rate through any intervention at a young age could lower the MRDT, thus accelerating aging. As such, the hypothesis disrupts the development of any anti-aging therapy, effectively making optimal aging treatments impossible.
The Gero team, however, realized that the SM correlation is a flawed assumption. Instead of using machine learning techniques for anti-aging therapy design, the researchers relied on an evidence-based science approach. Peter Fedichev and his team tried to determine the physical processes behind the SM correlation. In doing so, they realized the fundamental discrepancy between analytical considerations and the possibility of SM correlation. We worked through the entire life histories of thousands of C. elegans that were genetically identical, and the results showed that this correlation was indeed a pure fitting artifact, Fedichev saidin a press release.
Other studieshave questioned the validity of the SM correlation, but in their published study, Fedichev and his team were able to show how the SM correlation arises naturally as a degenerate manifold of Gompertz fit. This suggests that, instead of understanding SM correlation as a biological fact, it is really an artifactual property of the fit.
This discovery is particularly relevant now as more and more scientists are coming to the conclusion that aging is a disease and, as such, could be treated. They are working hard to find ways to extend human life, and many of theseanti-aging studies are yielding curious developments.
Elimination of SM correlation from theories of aging is good news, because if it was not just negative correlation between Gompertz parameters, but the real dependence, it would have banned optimal anti-aging interventions and limited human possibilities to life extension, Fedichev explained. In order words,human life extension has no definitive limit.
Visit link:
There is No Limit to Human Life Extension - Futurism
- Life Extension Information, Research and Products [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Life extension - Wikipedia, the free encyclopedia [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Forever Young - Short Documentary (Regenerative Medicine/Life Extension) - Video [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- An argument with a life extension denier - Video [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Life extension deniers part 3: their ignorance and stupidity - Video [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Life extension science, also known as anti-aging medicine, - Video [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- NEWS - Life Extension [Last Updated On: May 22nd, 2015] [Originally Added On: May 22nd, 2015]
- Life Extension Vitamins | Health Supplements | Garcinia ... [Last Updated On: May 22nd, 2015] [Originally Added On: May 22nd, 2015]
- The Life Extension Blog [Last Updated On: July 14th, 2015] [Originally Added On: July 14th, 2015]
- About Life Extension: Anti-Aging, Health Supplements ... [Last Updated On: August 7th, 2015] [Originally Added On: August 7th, 2015]
- Life Extension - Products on Sale, Coupons, Reviews, Free ... [Last Updated On: August 22nd, 2015] [Originally Added On: August 22nd, 2015]
- Life Extension - Reviews - eVitamins.com [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- Life Extension Manual - A Guide to Anti-aging, Genomes, and ... [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- Vitamins & Supplements | Life Extension Europe [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- Life Extension News - Life Enhancement Products [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- Life Extension diet & fitness | drugstore.com [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- Life Extension: Durk Pearson, Sandy Shaw: 9780446512299 ... [Last Updated On: September 3rd, 2015] [Originally Added On: September 3rd, 2015]
- Life Extension [Last Updated On: September 9th, 2015] [Originally Added On: September 9th, 2015]
- The Las Vegas A4M Conference - Life Extension [Last Updated On: September 22nd, 2015] [Originally Added On: September 22nd, 2015]
- Life Extension Technology and Tissue Regeneration [Last Updated On: October 25th, 2015] [Originally Added On: October 25th, 2015]
- Ann Arbor Life Extension [Last Updated On: October 28th, 2015] [Originally Added On: October 28th, 2015]
- Life Extension Supplements/Products: Antioxidants, Anti ... [Last Updated On: November 4th, 2015] [Originally Added On: November 4th, 2015]
- About Us - Life Extension [Last Updated On: January 27th, 2016] [Originally Added On: January 27th, 2016]
- Most Popular - Life Extension Vitamins [Last Updated On: February 12th, 2016] [Originally Added On: February 12th, 2016]
- Alcor Procedures - Alcor Life Extension Foundation [Last Updated On: February 14th, 2016] [Originally Added On: February 14th, 2016]
- Alcor Life Extension Foundation - Wikipedia, the free ... [Last Updated On: February 19th, 2016] [Originally Added On: February 19th, 2016]
- New... - Life Extension Vitamins [Last Updated On: June 30th, 2016] [Originally Added On: June 30th, 2016]
- Life Extension Mix Tablets, 315 tablets [Last Updated On: July 8th, 2016] [Originally Added On: July 8th, 2016]
- Directory of Innovative Anti-Aging Doctors, Health And ... [Last Updated On: July 18th, 2016] [Originally Added On: July 18th, 2016]
- Hormone / Prostate - Life Extension Vitamins [Last Updated On: July 26th, 2016] [Originally Added On: July 26th, 2016]
- Life Extension - Page 1 - Health Food Emporium [Last Updated On: September 24th, 2016] [Originally Added On: September 24th, 2016]
- Life Extension Super Bio-Curcumin -- 400 mg - 60 ... - Vitacost [Last Updated On: October 18th, 2016] [Originally Added On: October 18th, 2016]
- Life extension - Wikipedia [Last Updated On: October 25th, 2016] [Originally Added On: October 25th, 2016]
- Heart / Circulation - Life Extension Vitamins [Last Updated On: December 2nd, 2016] [Originally Added On: December 2nd, 2016]
- Life Extension - iHerb.com [Last Updated On: January 19th, 2017] [Originally Added On: January 19th, 2017]
- Orbital ATK files suit against DARPA - Inside Defense (subscription) [Last Updated On: February 8th, 2017] [Originally Added On: February 8th, 2017]
- Biotechnology xpert Jamie Metzl addresses realities of genetics revolution, Feb. 9 - Vail Daily News [Last Updated On: February 8th, 2017] [Originally Added On: February 8th, 2017]
- Human Life Could Be Extended Indefinitely, Study Suggests - EconoTimes [Last Updated On: February 10th, 2017] [Originally Added On: February 10th, 2017]
- DARPA hits snag in GEO satellite service plan - Network World [Last Updated On: February 10th, 2017] [Originally Added On: February 10th, 2017]
- Orbital ATK Sues DARPA Over Satellite-Repairing Robots | Inverse - Inverse [Last Updated On: February 13th, 2017] [Originally Added On: February 13th, 2017]
- Radical Life Extension Is Already Here, But We're Doing it ... [Last Updated On: February 13th, 2017] [Originally Added On: February 13th, 2017]
- Private Space Company Suing US Gov't For Stealing Their Idea ... - Daily Caller [Last Updated On: February 15th, 2017] [Originally Added On: February 15th, 2017]
- SRS's Melter 2 to be replaced | News | northaugustastar.com - The Star [Last Updated On: February 15th, 2017] [Originally Added On: February 15th, 2017]
- Acacia Mining sees 40 percent boost from mine extension | Reuters - Reuters [Last Updated On: February 15th, 2017] [Originally Added On: February 15th, 2017]
- Double-blind, randomized crossover study of intravenous infusion of ... - PR Newswire (press release) [Last Updated On: February 15th, 2017] [Originally Added On: February 15th, 2017]
- Only Human - New Republic [Last Updated On: February 17th, 2017] [Originally Added On: February 17th, 2017]
- Batteroo Boost, The Battery Life Extender Is Now Available Worldwide - PR Newswire (press release) [Last Updated On: February 17th, 2017] [Originally Added On: February 17th, 2017]
- Why Do People Want to Live So Long, Anyway? - TIME [Last Updated On: February 17th, 2017] [Originally Added On: February 17th, 2017]
- Major South African coal extension project on cards South32 - Creamer Media's Mining Weekly [Last Updated On: February 17th, 2017] [Originally Added On: February 17th, 2017]
- Evolution approves Cowal life extension project - Creamer Media's Mining Weekly [Last Updated On: February 17th, 2017] [Originally Added On: February 17th, 2017]
- Should We Die? - The Atlantic [Last Updated On: February 18th, 2017] [Originally Added On: February 18th, 2017]
- When Screening for Disease, Risk is as Important to Consider as ... - University of Virginia [Last Updated On: February 20th, 2017] [Originally Added On: February 20th, 2017]
- A UO lab digs into worms in the quest to lengthen human life - AroundtheO [Last Updated On: February 21st, 2017] [Originally Added On: February 21st, 2017]
- Life Extension Science Live Forever and Don't Pay Taxes - Nanalyze [Last Updated On: February 23rd, 2017] [Originally Added On: February 23rd, 2017]
- Who wants to live forever? Transhumanism's promise of eternal life - Irish Times [Last Updated On: March 18th, 2017] [Originally Added On: March 18th, 2017]
- Editorial March 29 2017 - Illawarra Mercury [Last Updated On: March 28th, 2017] [Originally Added On: March 28th, 2017]
- Life Extension and Insilico Medicine Use Artificial Intelligence to Develop Ageless Cell - WholeFoods Magazine [Last Updated On: March 28th, 2017] [Originally Added On: March 28th, 2017]
- Texas A&M Agri-Life Extension Invites Resident to Partake in - RGVProud [Last Updated On: March 28th, 2017] [Originally Added On: March 28th, 2017]
- Life Extension and Insilico Medicine Use Artificial Intelligence to Develop Ageless - WholeFoods Magazine [Last Updated On: March 31st, 2017] [Originally Added On: March 31st, 2017]
- How does where you live affect your life expectancy? | PBS NewsHour - PBS NewsHour [Last Updated On: May 12th, 2017] [Originally Added On: May 12th, 2017]
- Possible mine-life extension good news for contractors - Otago Daily Times [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- SES and MDA Announce First Satellite Life Extension Agreement - Space Daily [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- GARDENING: Reviving St. Augustine grass - Odessa American [Last Updated On: July 3rd, 2017] [Originally Added On: July 3rd, 2017]
- Does doxycycline treat h pylori ulcers - Shelf life extension program doxycycline - Longboat Key News [Last Updated On: July 6th, 2017] [Originally Added On: July 6th, 2017]
- This Study Could Help Extend the Human Lifespan - Futurism [Last Updated On: July 8th, 2017] [Originally Added On: July 8th, 2017]
- A surgeon aiming to do the first human head transplant says 'Frankenstein' predicted a crucial part of the surgery - South China Morning Post [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Silicon Valley looking to extend life | News, Sports, Jobs - The ... - Tiffin Advertiser Tribune [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- TransCanada still sees producer support for Keystone XL - WorldOil (subscription) [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- US approves $115m sale of F/A-18 Super Hornet upgrades to Switzerland - Airforce Technology [Last Updated On: August 1st, 2017] [Originally Added On: August 1st, 2017]
- BAE Systems sales fire up as tank orders roll in - shropshirestar.com [Last Updated On: August 2nd, 2017] [Originally Added On: August 2nd, 2017]
- New ICBM Cheaper Than Upgraded Minuteman: Boeing On GBSD - Breaking Defense [Last Updated On: August 3rd, 2017] [Originally Added On: August 3rd, 2017]
- BWXT Nuclear Energy Canada Awarded CA$34 Million Contract for Primary Heat Transport Motors - Business Wire (press release) [Last Updated On: August 3rd, 2017] [Originally Added On: August 3rd, 2017]
- BWXT Nuclear Energy Canada in Peterborough lands five-year, $34M deal to make primary heat transport motors for ... - Peterborough Examiner [Last Updated On: August 3rd, 2017] [Originally Added On: August 3rd, 2017]
- FAA Issues Structural Life Extension for Eclipse Jets | Business ... - Aviation International News [Last Updated On: August 3rd, 2017] [Originally Added On: August 3rd, 2017]
- BWXT NEC to provide seven heat transport motors for Bruce Power reactors - Power Technology [Last Updated On: August 4th, 2017] [Originally Added On: August 4th, 2017]
- Johanna and Mario Host Extension Leadership Workshop - KSST (press release) (registration) (blog) [Last Updated On: August 4th, 2017] [Originally Added On: August 4th, 2017]
- Can you take medications past their expiration date? - CBS News [Last Updated On: August 4th, 2017] [Originally Added On: August 4th, 2017]
- Ted Williams will be first baseball player to get 'American Masters' treatment - The Boston Globe [Last Updated On: August 4th, 2017] [Originally Added On: August 4th, 2017]
- Which Giant Tech Company Is Winning the Race to Be Skynet? - Vulture [Last Updated On: August 5th, 2017] [Originally Added On: August 5th, 2017]
- Can you take medications past their expiration date? - WBTW - Myrtle Beach and Florence SC [Last Updated On: August 5th, 2017] [Originally Added On: August 5th, 2017]