Previvorship: How to Beat Cancer Before It Happens – Baptist Health South Florida
Posted: November 4, 2020 at 12:01 pm
Science has enabled physicians to predict the likelihood of a woman getting breast cancer, much in the same way that meteorologists determine where and when a tornado will touch down and Amazon ensures you receive your order quickly. Predictive modeling, when coupled with powerful tools such as genetic testing, helps doctors prevent breast cancer or detect it early when it is most curable.
Miami Cancer Institutephysicians are at the forefront of these data-driven advances, working to prevent cancer as much as they are focused on curing it. Recently the Institute opened theBreast Cancer Prevention Clinicspecifically for those with a genetic predisposition to breast cancer or another underlying issue that makes them more susceptible. This concept ofprevivorship promotes fighting breast cancer before ever getting it.
In this clinic we will tailor a prevention plan for these patients, saidJane Mendez, M.D., chief of breast surgery at Miami Cancer Institute, so that instead of becoming a breast cancer survivor, they can continue as aprevivor. Meaning that even though you have the increased predisposition to breast cancer, we keep it at that.
With Breast Cancer Awareness Month in October, Dr. Mendez, sat down with Jonathan Fialkow, M.D., deputy medical director and chief of cardiology at Miami Cardiac & Vascular Institute, for a recent episode of theBaptist HealthTalk podcast, Breast Cancer: Risks, Prevention and Previvors. They discussed the latest breast cancer advances, as well as the basics such as screening guidelines and prevention recommendations.
Below are edited excerpts from their conversation. You can also access this and other Baptist HealthTalk podcast episodes in their entirety on your computer or smartphone or viaApple PodcastsandGoogle Podcasts.
Dr. Fialkow:
Lets start out by talking about what would be risk factors that would make a woman more likely to get breast cancer? What are the things weve identified that we want to pay attention to?
Dr. Mendez:
The two main risk factors for breast cancer are being a woman and getting older. So, even though wed like to forget about breast cancer the older we get, the more concerned we need to be about it. To that, you can add other factors such as family history as well as some environmental factors, some hormonal factors, and some of those are modifiable and some are not.
Dr. Fialkow:
What would the average person be told to do regarding screenings, mammograms, etc.?
Dr. Mendez:
For an average woman with no significant risk factors, the recommendation is a baseline mammogram anytime between age 30 to 40, and, then, provided there are no abnormalities, an annual mammogram starting at age 40. And we know the denser the breast tissue, the more important it is to complement that with a breast ultrasound. Its part of doing a more thorough evaluation.
Dr. Fialkow:
You mentioned some of the non-modifiable risk factors, things you cant change. One is family history, which speaks to genetics. Can you unpack that a bit?
Dr. Mendez:
I want to make it clear that only 10 percent of breast cancers occur in women who have a family history of breast cancer and 5 percent have an identifiable mutation or something in the genetic makeup that really predisposes them to breast cancer. At the time of our initial consultation, or as part of our follow-up, we ask very specific questions about family history. Who was the relative? Is this your mother, your sister? Also we would want to know about any male breast cancer in the family or any other cancers in the family. We ask about ovarian cancer because thats related to the BRCA genes, which are the most prevalent genes associated with breast cancer. But we also ask about colon cancer, prostate cancer, pancreas, stomach cancer, because we know that certain genetic mutations are also associated with the gene. It helps us stratisfy the risk so we can determine who might benefit from a genetic consultation and actual genetic testing.
Dr. Fialkow:
If someone is high risk, what is the next step?
Dr. Mendez:
We have models to help us calculate. One that is most commonly used is the Tyrer-Cuzick Eighth Edition model, where it takes a lot of these factors in consideration. It gives us a percentage probability of that woman developing breast cancer within 10 years and during their lifetime. If someone indeed has high risk, usually greater than 20 percent, in addition to the increased surveillance, we will follow that patient with a breast MRI.
Dr. Fialkow:
During COVID-19 were seeing a decrease in women getting their mammograms. Can you speak to how important it is to maintain your screening, your routine screening process?
Dr. Mendez:
Its very important to maintain the screening. Early detection is key for improved outcomes and improved survival. In addition to screening, its important to know your family history and your body. I cannot underscore the importance also of breast self-exam. I can assure patients that the imaging centers are following COVID-19 guidelines in terms of safety. I encourage all women to go and seek their mammogram so that we can attend to their needs and continue with prevention.
Dr. Fialkow:
Can we talk a little about the Breast Cancer Prevention Clinic at Miami Cancer Institute?
Dr. Mendez:
In this clinic we are trying to identify a very specific patient population at increased risk of breast cancer because of their family history, certain pathologic conditions, previous radiation or because they have been identified to have some of these high-risk mutations. We will tailor a prevention plan, including genetic consultation if needed, and nutrition and exercise plans so that they can monitor all of the different components that are critical in order to maintain a healthy lifestyle. Instead of becoming a breast cancer survivor, they can continue as aprevivor. So thats a great concept.
Dr. Fialkow:
Theres also aBenign Breast Cancer Clinic. Could you speak a little about the benefit of that?
Dr. Mendez:
This clinic focuses on non-cancerous conditions. We make sure that in their clinical exam, everything is normal, as well as in their imaging. These are women who might be having breast pain or cysts or other benign conditions and need to be reassured by an expert so that they can move on, and, receive proper follow-up when needed.
Dr. Fialkow:
And how about survivorship programs?
Dr. Mendez:
Its not only about surviving the breast cancer, but also living your life with good quality and any adjustments. Currently in the United States we have 3 million breast cancer survivors because of all the advances and technology. We have a whole program of survivorship, everything from psychological support to yoga classes, to acupuncture, to nutrition and obviously healing. Whatever is needed to keep the patient not only cancer-free, but with great quality of life.
Tags: breast cancer, breast cancer awareness month, Miami Cancer Institute
Read more here:
Previvorship: How to Beat Cancer Before It Happens - Baptist Health South Florida
- HitXP Science of Genetics behind the Hindu Gotra System ... [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Size Genetics - Male Enhancement Reviews [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Male Infertility | Genetic Abnormalities or Male ... [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Male infertility - Wikipedia, the free encyclopedia [Last Updated On: May 4th, 2015] [Originally Added On: May 4th, 2015]
- Androgenic alopecia - Wikipedia, the free encyclopedia [Last Updated On: May 7th, 2015] [Originally Added On: May 7th, 2015]
- Difference Between Male and Female BirdsGenetics and ... [Last Updated On: May 7th, 2015] [Originally Added On: May 7th, 2015]
- URNotAlone Profile for Lynda Flores, Genetic Male Straight ... [Last Updated On: May 21st, 2015] [Originally Added On: May 21st, 2015]
- Understanding Genetics [Last Updated On: May 31st, 2015] [Originally Added On: May 31st, 2015]
- Male - Wikipedia, the free encyclopedia [Last Updated On: May 31st, 2015] [Originally Added On: May 31st, 2015]
- WHO | Gender and Genetics [Last Updated On: May 31st, 2015] [Originally Added On: May 31st, 2015]
- The Genetics of Male Infertility - The Turek Clinic [Last Updated On: June 13th, 2015] [Originally Added On: June 13th, 2015]
- Male Hair Loss All You Need To Know - The Belgravia Centre [Last Updated On: June 29th, 2015] [Originally Added On: June 29th, 2015]
- Male-pattern hair loss - Wikipedia, the free encyclopedia [Last Updated On: August 1st, 2015] [Originally Added On: August 1st, 2015]
- Genetics - biology [Last Updated On: August 2nd, 2015] [Originally Added On: August 2nd, 2015]
- Are People Born Gay? Genetics and Homosexuality [Last Updated On: August 20th, 2015] [Originally Added On: August 20th, 2015]
- Hormone and genetic study in male to female transsexual ... [Last Updated On: September 21st, 2015] [Originally Added On: September 21st, 2015]
- Cloning Myths - Learn Genetics [Last Updated On: September 25th, 2015] [Originally Added On: September 25th, 2015]
- Sensorineural deafness and male infertility - Genetics ... [Last Updated On: October 17th, 2015] [Originally Added On: October 17th, 2015]
- Workable male sterility systems for hybrid rice: Genetics ... [Last Updated On: October 22nd, 2015] [Originally Added On: October 22nd, 2015]
- Proband - Wikipedia, the free encyclopedia [Last Updated On: October 26th, 2015] [Originally Added On: October 26th, 2015]
- Y chromosome - Genetics Home Reference [Last Updated On: October 29th, 2015] [Originally Added On: October 29th, 2015]
- Genetics - NHS Choices [Last Updated On: November 1st, 2015] [Originally Added On: November 1st, 2015]
- Genetics / Does the male or female carrier the gene for twins. [Last Updated On: March 13th, 2016] [Originally Added On: March 13th, 2016]
- The Genetics of Balding | Understanding Genetics [Last Updated On: April 25th, 2016] [Originally Added On: April 25th, 2016]
- Male Infertility - Genetics & IVF Institute [Last Updated On: May 21st, 2016] [Originally Added On: May 21st, 2016]
- Scientist Explains the Genetics of Male Pattern Baldness [Last Updated On: June 16th, 2016] [Originally Added On: June 16th, 2016]
- Definitions for Terms in Genetics Problems [Last Updated On: August 24th, 2016] [Originally Added On: August 24th, 2016]
- Genetics of human male infertility. [Last Updated On: August 24th, 2016] [Originally Added On: August 24th, 2016]
- BEHAVIORAL GENETICS: THE SCIENCE OF ... - PubMed Central (PMC) [Last Updated On: September 13th, 2016] [Originally Added On: September 13th, 2016]
- Review of the Status of Aquaculture Genetics [Last Updated On: September 13th, 2016] [Originally Added On: September 13th, 2016]
- Genetics of Skin Cancer (PDQ)Health Professional Version [Last Updated On: September 22nd, 2016] [Originally Added On: September 22nd, 2016]
- Genetics of Prostate Cancer (PDQ)Health Professional ... [Last Updated On: September 22nd, 2016] [Originally Added On: September 22nd, 2016]
- Genetics of Breast and Gynecologic Cancers (PDQ)Health ... [Last Updated On: September 28th, 2016] [Originally Added On: September 28th, 2016]
- Evolution - Wikipedia [Last Updated On: October 27th, 2016] [Originally Added On: October 27th, 2016]
- Human - Wikipedia [Last Updated On: November 12th, 2016] [Originally Added On: November 12th, 2016]
- Genetics - Wikipedia [Last Updated On: November 23rd, 2016] [Originally Added On: November 23rd, 2016]
- Beefalo - Wikipedia [Last Updated On: December 4th, 2016] [Originally Added On: December 4th, 2016]
- Drosophila melanogaster - Wikipedia [Last Updated On: December 26th, 2016] [Originally Added On: December 26th, 2016]
- Breast CancerPatient Version - National Cancer Institute [Last Updated On: January 6th, 2017] [Originally Added On: January 6th, 2017]
- Sex - Wikipedia [Last Updated On: January 24th, 2017] [Originally Added On: January 24th, 2017]
- The 44 Chromosome Man | Understanding Genetics [Last Updated On: February 5th, 2017] [Originally Added On: February 5th, 2017]
- Binary thought suppresses identity - The Daily Evergreen [Last Updated On: February 8th, 2017] [Originally Added On: February 8th, 2017]
- Tortoiseshell cat - Wikipedia [Last Updated On: February 8th, 2017] [Originally Added On: February 8th, 2017]
- Entrepreneurship Is Genetic, And South Africa Is The Ideal Environment For Young Entrepreneurs To Thrive - Huffington Post South Africa (blog) [Last Updated On: February 8th, 2017] [Originally Added On: February 8th, 2017]
- Women in Data Science conference highlights female participation in male-dominated field - Daily Free Press (subscription) [Last Updated On: February 11th, 2017] [Originally Added On: February 11th, 2017]
- Male Contraceptives Have A Messy History And A Bright Future - Yahoo News [Last Updated On: February 11th, 2017] [Originally Added On: February 11th, 2017]
- The impact of RABL2B gene (rs144944885) on human male infertility in patients with oligoasthenoteratozoospermia ... - UroToday [Last Updated On: February 11th, 2017] [Originally Added On: February 11th, 2017]
- More Than 200 Baldness-Linked Genetic Markers Found - Yahoo News [Last Updated On: February 21st, 2017] [Originally Added On: February 21st, 2017]
- Can Your Anxiety Impact How Long You Last In Bed? - Men's Health [Last Updated On: February 21st, 2017] [Originally Added On: February 21st, 2017]
- Genetic data show mainly men migrated from the Pontic steppe to Europe 5000 years ago - Phys.Org [Last Updated On: February 21st, 2017] [Originally Added On: February 21st, 2017]
- Men inherit male pattern baldness from their mum's side of the family ... - Metro [Last Updated On: February 21st, 2017] [Originally Added On: February 21st, 2017]
- Experts Are One Step Closer To Predicting A Man's Risk For Hair Loss - Huffington Post [Last Updated On: February 21st, 2017] [Originally Added On: February 21st, 2017]
- Baldness linked to over 280 genes - BioNews [Last Updated On: February 21st, 2017] [Originally Added On: February 21st, 2017]
- Genetic basis for male baldness identified in large-scale study - Medical News Today [Last Updated On: February 21st, 2017] [Originally Added On: February 21st, 2017]
- Genetic data show mainly men migrated from the Pontic steppe to ... - Science Daily [Last Updated On: February 23rd, 2017] [Originally Added On: February 23rd, 2017]
- Thousands of horsemen may have swept into Bronze Age Europe, transforming the local population - Science Magazine [Last Updated On: February 23rd, 2017] [Originally Added On: February 23rd, 2017]
- Cohen wins Gates grant for her new take on male contraception - Cornell Chronicle [Last Updated On: June 23rd, 2017] [Originally Added On: June 23rd, 2017]
- A Florida higher-ed official said women's genetics may be keeping ... - Washington Post [Last Updated On: June 23rd, 2017] [Originally Added On: June 23rd, 2017]
- Florida higher education official said women may earn less than men because of genetics - New York Daily News [Last Updated On: June 23rd, 2017] [Originally Added On: June 23rd, 2017]
- Twins Separated at Birth Reveal Staggering Influence of ... [Last Updated On: June 23rd, 2017] [Originally Added On: June 23rd, 2017]
- Scientific studies favor male miceand that could hurt a lot of humans - Popular Science [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- So Cal mountain lions' low genetic diversity threatens population - Davis Enterprise [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- Horse Tale: Oriental Stallions Dominate Horse DNA, Gene Study Shows - NBCNews.com [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- sex chromosome | genetics | Britannica.com [Last Updated On: July 1st, 2017] [Originally Added On: July 1st, 2017]
- The problematics of genetics and the Aryan issue - The Hindu [Last Updated On: July 3rd, 2017] [Originally Added On: July 3rd, 2017]
- Scientists arming new weapon against dengue, malaria mosquitoes - The Indian Express [Last Updated On: July 3rd, 2017] [Originally Added On: July 3rd, 2017]
- Fertility and Genetics - Affordable High Quality Fertility ... [Last Updated On: July 5th, 2017] [Originally Added On: July 5th, 2017]
- Aryan Invasion May Have Transformed India's Bronze-Age Population - Live Science [Last Updated On: July 6th, 2017] [Originally Added On: July 6th, 2017]
- How Masculinity Can Be Bad For Men's Health - WUNC [Last Updated On: July 6th, 2017] [Originally Added On: July 6th, 2017]
- Nilgiris pale tiger an 'aberrant genetic mutation' - The Hindu [Last Updated On: July 8th, 2017] [Originally Added On: July 8th, 2017]
- Evolution and war: The 'deep roots' theory of human violence - Genetic Literacy Project [Last Updated On: July 8th, 2017] [Originally Added On: July 8th, 2017]
- Hair loss in men: THIS shower habit could be why you're going bald - Express.co.uk [Last Updated On: July 10th, 2017] [Originally Added On: July 10th, 2017]
- Don't Blame Your Mom's Dad for Male Pattern Baldness - Inverse [Last Updated On: July 13th, 2017] [Originally Added On: July 13th, 2017]
- Falling sperm counts are linked to endocrine-disrupting chemicals - MinnPost [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- Should genetic engineering be used as a tool for conservation? - chinadialogue [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- Trinity Researchers Lead Analysis of Portugal and Spain's Genetic History - The University Times [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- Williams Professor Wins Grants to Study Evolutionary Genetics - iBerkshires.com [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- History News of the Week: The Biblical Canaanites' Modern Descendants - New Historian [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- When the male fruit fly gets a headache - Haaretz [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]
- Genetics LadyFrontbum [Last Updated On: July 31st, 2017] [Originally Added On: July 31st, 2017]