ABC News recently reported on the societal implications of a pre-implantation genetic diagnosis procedure now being allowed in Germany. This procedure is also available at the IVF New Jersey Fertility Center, which offers insight as to its benefits.

(PRWEB) February 26, 2013

While pre-implantation genetic diagnosis (PGD) is not practiced in many countries, it is a fairly common and frequently successful procedure in the United States. Its a type of prenatal genetic testing that is nonetheless innovative, providing valuable information for parents-to-be. By screening embryos for genetic abnormalities prior to the embryo attaching to the uterus, couples are increasing the chance of a successful pregnancy and decrease the risk of passing certain genetic diseases to their children.

The list of more than 30 diseases that preimplantation genetic diagnosis/genetic testing can detect at IVF New Jersey is continually evolving, and includes the following: Adenosine deaminase deficiency, Alpha-1-antitrypsin deficiency, Alpers Syndrome, Cystic fibrosis, Gauchers disease, Hemophilia A and B, Huntingtons disease, Muscular dystrophy (Duchenne and Becker), Sickle cell disease, Spinal muscular atrophy, Tay Sachs disease.

At IVF New Jersey Fertility Center, the PGD procedure begins with in vitro fertilization (IVF), using hormones to stimulate the growth and recovery of multiple eggs from the ovaries in order to form several embryos for evaluation by PGD, thus increasing the chances of finding normal or unaffected embryos for transferring back to the uterus. From that point, the process of evaluation of these embryos by PGD takes place in a laboratory and requires a biopsy at one of the two developmental stages (cleaved embryo, three days after fertilization or blastocyst, five to six days after fertilization). The stage of the embryo is determined on a case-by-case basis.

The embryo biopsy is performed under microscopic guidance using a pipette to gently aspirate the embryonic cells and an opening is made in the shell surrounding the embryo allowing access to the dividing cells. The goal is to obtain enough cellular material to carry on the PGD analysis without harming the embryo and only embryos with normal biopsy results are used for transfer/implantation.

PGD was developed to check for genetic and chromosomal abnormalities that would cause miscarriages, birth defects or fatal illnesses, and the list of diseases that pre-implantation genetic testing can detect is consistently growing at IVF New Jersey. While PGD increases couples chances of having a healthy offspring, experts at IVF New Jersey recommend that patients get confirmatory genetic testing during pregnancy like CVS or amniocentesis to ensure their child is free of other conditions.

Women and couples are encouraged to visit http://www.ivfnj.com to learn more about PGD and the fertility center.

About IVF New Jersey Fertility Center:

IVF New Jersey Fertility Center was founded in 1990 with the goal of creating a fertility practice that combines the best of big-city medicine with the personalized care of a private setting. For the past 22 years, IVF NJ has helped bring thousands of babies to couples in the metropolitan region and throughout the world. IVF NJs unique cutting-edge facilities allow the physicians to perform all standard (delete) fertility diagnostic and treatment procedures under one roof, all in a comfortable, private, non-hospital setting. IVF NJ is one of the largest fertility centers in the nation with some of the highest success rates in the U.S. according to the Center for Disease Control (CDC). For more information visit http://www.ivfnj.com.

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IVF New Jersey Fertility Center Offering Sought-After Pre-Implantation Genetic Diagnosis Tests

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CBC New Gene Therapy for Leukemia

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CBC New Gene Therapy for Leukemia - Video

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"Immunology", Bone Marrow Transplantation or Gene Therapy Can Be Useful to Correct Genetic Defects

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"Immunology", Bone Marrow Transplantation or Gene Therapy Can Be Useful to Correct Genetic Defects - Video

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Intracerebral gene therapy for lysosomal storage diseases
Animation movie of intracerebral gene therapy approach for the treatment of lysosomal storage diseases. This film was produced by LYSOGENE in collaboration with the students from the first year of scientific illustration design at the Estienne school.

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Intracerebral gene therapy for lysosomal storage diseases - Video

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Stem Cell Therapy Bio1103 Group 29 AM
Peyton Manning and Stem Cell Research

By: megmitchell93

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Stem Cell Therapy Bio1103 Group 29 AM - Video

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Group 52AM- Stem Cell Therapy
Group 52 (BIOL1103/11:00AM) clearly illustrates the topic of Stem Cell Therapy through a class project based on a member of their own group who is considering Stem Cell Therapy.

By: Savannah Kelley

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Group 52AM- Stem Cell Therapy - Video

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Age-Related Macular Degeneration and Retinal Stem Cell Therapy
The problems of AMD and its potential treatment with Retinal Stem Cell Therapy BIO 1103 at UGA

By: grayson3447

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Stem Cell Therapy Boston - New England Center for Hair Restoration
At New England Center for Hair Restoration, our Boston area specialists are working with stem cell therapy in a research environment to discover the many ways it can assist in treating hair loss. We expect to see phenomenal results, as we have already discovered many reasons as to why stem cells can be effective as a hair loss solution. If you are interested in learning more about stem cell therapy, or any other hair loss treatments available at our Boston hair restoration center, please visit http://www.nehair.com. You may contact our hair loss center at 465 S. Washington Street North Attleborough, MA 02760 (855) 563-4247, (855) 5 NE HAIR http://www.nehair.com

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Stem Cell Therapy Boston - New England Center for Hair Restoration - Video

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SILVER SPRING, Md., Feb. 25, 2013 (GLOBE NEWSWIRE) -- Nuvilex, Inc. (NVLX), an international biotechnology and clinical stage provider of natural products and cell and gene therapy solutions for the treatment of diseases, discussed today additional reasons for its subsidiary, Medical Marijuana Sciences, Inc., to develop treatments for brain and pancreatic cancer that are based on cannabinoids from Cannabis sativa.

Plants have been the source of many well-known drugs for the treatment of a myriad of diseases, and cancer is no exception. For several years, the National Cancer Institute (NCI) in the U.S. has conducted a program that searches worldwide for new anticancer drugs from various natural sources, including plants. By using cannabinoids from Cannabis, such as cannabidiol, as the basis for developing treatments for deadly forms of cancer, Medical Marijuana Sciences, Inc. is, in fact, embracing the NCI's efforts.

There are many examples of cancer drugs from plants that are in widespread use throughout the world for a variety of cancers. Prominent among these are paclitaxel (Taxol(R)) from the bark of the Pacific yew tree (Taxus brevifolia), vincristine (Oncovin(R)) and vinblastine (Velban(R)) from the periwinkle plant and their synthetic derivatives vindesine (Eldisine(R)) and vinorelbine (Navelbine(R)), and Camptothecin(TM) from the bark and stem of the small Camptotheca acuminata tree native to China and Tibet. Derivatives of Camptothecin(TM) that are used in cancer treatment include topotecan (Hycantin(R)) and irinotecan (Camptosar(R)).

Typically, plant-derived drugs are used alone or with other drugs in combination chemotherapy treatment regimens. Some of these drugs are targeted to the treatment of one or two forms of cancer, while others are used to treat several forms of the disease. Furthermore, these naturally-occurring drugs have inspired the production of derivatives that are also used for cancer treatment.

Nuvilex's COO, Dr. Gerald Crabtree stated "By using cannabinoids for the development of treatments for some of the deadliest forms of cancer, Medical Marijuana Sciences, Inc. is building upon the strong foundation of very important cancer drugs that have come from plants. Given the knowledge that has accumulated in the scientific literature over the past few years, we feel that cannabinoids represent an excellent opportunity for the development of such treatments."

Dr. Robert Ryan, President and CEO of Nuvilex commented, "We are excited by the prospect that Nuvilex, through its new subsidiary Medical Marijuana Sciences, can contribute to the already strong arsenal of plant-derived anticancer agents."

About Nuvilex

Nuvilex, Inc. (NVLX) has been a provider of all-natural products for many years. The company has been expanded to increase its natural product-based footprint through medical marijuana studies. We are an international biotechnology provider of live, therapeutically valuable, encapsulated cells and services for research and medicine. New developments by our company and subsidiaries will be substantial as we have been working on many fronts to move us forward. Our company's offerings will ultimately include cancer, diabetes and other treatments using the Company's natural product knowledge, product base, cell and gene therapy expertise, and live-cell encapsulation technology in addition to other new products currently under development.

The Nuvilex, Inc. logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=13494

Safe Harbor Statement

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Nuvilex's Subsidiary, Medical Marijuana Sciences, Inc., Presents Further Rationale for Use of Cannabinoids in ...

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Feb. 25, 2013 Environmental exposure to bisphenol A (BPA), a widespread chemical found in plastics and resins, may suppress a gene vital to nerve cell function and to the development of the central nervous system, according to a study led by researchers at Duke Medicine.

The researchers published their findings -- which were observed in cortical neurons of mice, rats and humans -- in the journal Proceedings of the National Academy of Sciences on Feb. 25, 2013.

"Our study found that BPA may impair the development of the central nervous system, and raises the question as to whether exposure could predispose animals and humans to neurodevelopmental disorders," said lead author Wolfgang Liedtke, M.D., PhD, associate professor of medicine/neurology and neurobiology at Duke.

BPA, a molecule that mimics estrogen and interferes with the body's endocrine system, can be found in a wide variety of manufactured products, including thermal printer paper, some plastic water bottles and the lining of metal cans. The chemical can be ingested if it seeps into the contents of food and beverage containers.

Research in animals has raised concerns that exposure to BPA may cause health problems such as behavioral issues, endocrine and reproductive disorders, obesity, cancer and immune system disorders. Some studies suggest that infants and young children may be the most vulnerable to the effects of BPA, which led the U.S. Food and Drug Administration to ban the use of the chemical in baby bottles and cups in July 2012.

While BPA has been shown to affect the developing nervous system, little is understood as to how this occurs. The research team developed a series of experiments in rodent and human nerve cells to learn how BPA induces changes that disrupt gene regulation.

During early development of neurons, high levels of chloride are present in the cells. These levels drop as neurons mature, thanks to a chloride transporter protein called KCC2, which churns chloride ions out of the cells. If the level of chloride within neurons remains elevated, it can damage neural circuits and compromise a developing nerve cell's ability to migrate to its proper position in the brain.

Exposing neurons to minute amounts of BPA alters the chloride levels inside the cells by somehow shutting down the Kcc2 gene, which makes the KCC2 protein, thereby delaying the removal of chloride from neurons.

MECP2, another protein important for normal brain function, was found to be a possible culprit behind this change. When exposed to BPA, MECP2 is more abundant and binds to the Kcc2 gene at a higher rate, which might help to shut it down. This could contribute to problems in the developing brain due to a delay in chloride being removed.

These findings raise the question of whether BPA could contribute to neurodevelopmental disorders such as Rett syndrome, a severe autism spectrum disorder that is only found in girls and is characterized by mutations in the gene that produces MECP2.

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BPA may affect the developing brain by disrupting gene regulation

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One week of poor sleep can disrupt hundreds of genes linked to stress, immunity and inflammation, research has shown.

Sleep deficiency is associated with a host of conditions including obesity, heart disease and mental impairment. But scientists are still trying to understand the molecular mechanisms involved.

For the new study, researchers examined gene activity in 26 sleep-deprived volunteers. They found that insufficient sleep had an impact on more than 700 genes - some had their activity dampened, while others became extra-active.

Those affected included genes associated with the circadian night and day "body clock" cycle, metabolism, and immune and stress responses.

Poor sleep also altered chromatin - the DNA and protein "packaging" that plays an important role in gene regulation.

The scientists, led by Professor Derk-Jan Dijk from the University of Surrey, wrote in the journal Proceedings of the National Academy of Sciences: "Biological processes affected included chromatin modification, gene-expression (activity) regulation, macro-molecular metabolism, and inflammatory, immune and stress responses. The identified biological processes may be involved with the negative effects of sleep loss on health, and highlight the inter-relatedness of sleep homeostasis (stability), circadian rhythmicity, and metabolism."

Prof Dijk's team analysed RNA - the messenger chemical that delivers coded "instructions" from the genes to cells - in the blood of volunteers. RNA can be used as a tool to measure gene activity.

Participants were exposed to a week of poor sleep during which they slept no more than six hours a night. At the end of this time, they had to stay awake for around 40 hours while RNA samples were collected at three hourly intervals. The results were compared with the effect on the same volunteers of sleeping up to 10 hours a night for a week.

The scientists noted: "Sleep obtained in the sleep-restriction condition was not sufficient to maintain alertness or performance."

The findings may be relevant to many people living in industrialised societies, they said. In the US, 30% of adults reported getting six hours sleep or less a night on average.

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Lack of sleep affects gene activity

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By Duke Medicine News and Communications

DURHAM, N.C. -- Environmental exposure to bisphenol A (BPA), a widespread chemical found in plastics and resins, may suppress a gene vital to nerve cell function and to the development of the central nervous system, according to a study led by researchers at Duke Medicine.

The researchers published their findings - which were observed in cortical neurons of mice, rats and humans - in the journal Proceedings of the National Academy of Sciences on Feb. 25, 2013.

"Our study found that BPA may impair the development of the central nervous system, and raises the question as to whether exposure could predispose animals and humans to neurodevelopmental disorders," said lead author Wolfgang Liedtke, M.D., PhD, associate professor of medicine/neurology and neurobiology at Duke.

BPA, a molecule that mimics estrogen and interferes with the body's endocrine system, can be found in a wide variety of manufactured products, including thermal printer paper, some plastic water bottles and the lining of metal cans. The chemical can be ingested if it seeps into the contents of food and beverage containers.

Research in animals has raised concerns that exposure to BPA may cause health problems such as behavioral issues, endocrine and reproductive disorders, obesity, cancer and immune system disorders. Some studies suggest that infants and young children may be the most vulnerable to the effects of BPA, which led the U.S. Food and Drug Administration to ban the use of the chemical in baby bottles and cups in July 2012.

While BPA has been shown to affect the developing nervous system, little is understood as to how this occurs. The research team developed a series of experiments in rodent and human nerve cells to learn how BPA induces changes that disrupt gene regulation.

During early development of neurons, high levels of chloride are present in the cells. These levels drop as neurons mature, thanks to a chloride transporter protein called KCC2, which churns chloride ions out of the cells. If the level of chloride within neurons remains elevated, it can damage neural circuits and compromise a developing nerve cell's ability to migrate to its proper position in the brain.

Exposing neurons to minute amounts of BPA alters the chloride levels inside the cells by somehow shutting down the Kcc2 gene, which makes the KCC2 protein, thereby delaying the removal of chloride from neurons.

MECP2, another protein important for normal brain function, was found to be a possible culprit behind this change. When exposed to BPA, MECP2 is more abundant and binds to the Kcc2 gene at a higher rate, which might help to shut it down. This could contribute to problems in the developing brain due to a delay in chloride being removed.

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Health Research: BPA May Affect the Developing Brain by Disrupting Gene Regulation

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Agricultural Experiment Station at the University of Arizona
Randy Ryan of the Agricultural Experiment Station at the University of Arizona explains the benefits of genetic engineering to Arizona #39;s cotton crop. Read more about cotton today in Arizona, arizonaexperience.org

By: Arizona Experience

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Agricultural Experiment Station at the University of Arizona - Video

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Elocution Competition Winning Speech - The Role of Genetic Engineering in our Society
Maulik Jain received an accolade for his speech at the Nehru Science Center, Mumbai. His topic was - "The Role of Genetic Engineering in our Society." He is currently an aspiring student studying in the 9th Grade at Jamnabai Narsee School (JNS). Please like his video and leave behind a comment.

By: Maulik Jain

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Elocution Competition Winning Speech - The Role of Genetic Engineering in our Society - Video

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Tott #39;s Play Xbox Live Indie Games A
The XBLIG marketplace has always been a collection of the finest examples of video game available as long as you don #39;t count literally anything else. ~~~~ About Paddy: With the body of a hula girl, the hands of Shaquille O #39;Neal and the mind of a Bulgarian airport, Paddy is the pinnacle of genetic engineering. About Alex: Alex is revered in his home town of York as he was the one who finally killed Margaret Thatcher. He chopped her head off with a skateboard. FACEBOOK http://www.facebook.com WE DON #39;T HAVE ANY PRESENCE IN OTHER SOCIAL NETWORK SITES BUT THE FACEBOOK PAGE IS INCREDIBLY OKAY.

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Tott's Play Xbox Live Indie Games A - Video

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BPA is back in the news, now that a new study has linked the controversial chemical to potentially dangerous effects on a child's developing nervous system.

The study only looked at mice, but the researchers are concerned the findings may apply to humans as well.

"Our study found that BPA may impair the development of the central nervous system, and raises the question as to whether exposure could predispose animals and humans to neurodevelopmental disorders," study author Dr. Wolfgang Liedtke, an associate professor of medicine and neurobiology at Duke University in Durham, N.C., said in a press release.

BPA, or bisphenol A, is widely available in consumer packaging, used to line aluminum cans to protect them from corrosion and also used in plastics such as bottles, tableware and food storage containers.

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The chemical mimics estrogen in the body which in turn could disrupt the endocrine system (hormones), leading to negative health effects. Previous studies have linked BPA exposure to behavioral disorders, cancer, immune system problems and reproductive disorders, according to the researchers. Recent studies in children have tied BPA to risk for obesity, thyroid problems and kidney damage.

BPA is banned in the European Union and Canada, but the U.S. Food and Drug Administration (FDA) has only banned the chemical from for manufacturing of baby bottles and sippy cups as of July 2012.

For the new study, published online Feb. 25 in Proceedings of the National Academy of Sciences, researchers exposed mice's nerve cells, or neurons, to BPA. When neurons are developed, high levels of the ion chloride are present, but eventually chloride levels fall because a transporter protein called KCC2 "churns" it out of cells. Too much chloride in cells can damage nervous system pathways and disrupt the developing neuron's ability to move to where it needs to in the brain.

The researchers discovered when exposing the mice to minute amounts of BPA, the gene that makes KCC2 shut down, which kept chloride longer in the neurons. They suspect the BPA made a different type of protein -- known as MECP2 -- more abundant in neurons, which in turn bound to KCC2 and shut it down.

That's important, scientists said, because it raises questions about whether BPA exposure could be linked to disorders such as the severe autism spectrum disorder Rett syndrome, which is characterized by mutations in a gene that makes MECP2. Rett syndrome is the most common cause of intellectual disability in girls, according to the researchers.

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BPA exposure linked to genetic changes that alter brain development

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Ascent vs Heroic Lei Shi 25 man
This is Ascent #39;s first kill of Heroic Lei Shi in Terrace of Endless Springs. Genetics decided to ninja pull at the start which is why fraps started at 97% or whatever. PoV: Mallagint (Guardian Druid) Guild: Ascent (Horde) Server: Thrall-US

By: Sujay Darji

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Ascent vs Heroic Lei Shi 25 man - Video

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Harlem Geeks
Courtesy of the department of Human Molecular Genetics and Biochemistry, the Faculty of Medicine, Tel Aviv University. Hey, If we can #39;t publish on Nature, at least we can publish on Youtube,

By: yairpozn

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Harlem Geeks - Video

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Dr. Raja Flores on Lung Cancer and Genetics
Mount Sinai #39;s Dr. Raja Flores discusses how family history influences lung cancer. Dr. Flores is a recognized leader in the field of Thoracic Surgery for his pioneering efforts in the treatment of mesothelioma. He has established VATS lobectomy, a minimally invasive approach using three small incisions, as the gold standard in the surgical treatment of lung cancer. He published two sentinel studies validating its oncological effectiveness by demonstrating equivalent survival and recurrence rates with fewer complications and shorter hospital stays when compared to standard thoracotomy.

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Probability and Punnett Square Notes
Genetics unit

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Probability and Punnett Square Notes - Video

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Gun Bros 2 Available FREE on iOS! (Gameplay)
Untold years after the first TOOL wars, the Tyrannical Oppressors Of Life have returned to finish the job. Only the Freakishly Rugged Advanced Genetics Galactic Enforcement Division (FRAGGED) agents Percy and Francis Gun stand in their way. Armed with a new array of highly advanced and ridiculously destructive weapons, the Gun Bros are once again defending the galaxy from the TOOL insurgency. It is a time to innovate and eradicate. The last conflict has left both sides scrambling to rebuild their armories. Old Xplodium mines have been reopened and even decommissioned factories are once again roaring to life as the conflict escalates. It is up to Percy and Francis to stop this threat from reemerging with an even more devastating arsenal of killing machines. The Gun Bros are back and, once again, responsible for defending the galaxy. Luckily, they #39;ve got access to a host of new gear that will help them defeat TOOL REAL-TIME MULTIPLAYER! Battle the TOOL hordes with your Gamecenter friends, head over to the all-new Endless Mode and check it out! NEW GUNS MODS! Choose from a broad range of weapons; from pistols rocket launchers to new and improved laser weapons shotguns. Collect MODS and strap them on your weapon to gain secondary, tertiary and even quaternary fire modes! Players can even unleash multiple MODS at once! MEGA BOSS BATTLES! Battle against the Pus Titan, Maullusk and The Broliminator! These monstrous bosses are enough to get any Bro excited... THE ...

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Gun Bros 2 Available FREE on iOS! (Gameplay) - Video

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RAP 4 Genetics

By: WWUbiology101

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RAP 4 Genetics - Video

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Hair Loss in Women Boston - New England Center for Hair Restoration
Female hair loss can occur as the result of many possible factors, including genetics, age, reaction to certain medications, and androgenetic alopecia. Not all female hair loss is permanent, and our Boston area doctors offer customized treatment to help you regain your hair and confidence. At New England Center for Hair Restoration, hair loss center near Boston, Dr. Ryan Welter and Dr. Clark Tan offer many solutions that are safe and effective to restore your hair and regain your confidence. For more information, please visit http://www.nehair.com. You may contact our hair loss center at 465 S. Washington Street North Attleborough, MA 02760 (855) 563-4247, (855) 5 NE HAIR http://www.nehair.com

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Temple Bodycare Part 4 Section 1
Continuing in this straight-talking, life-transforming series Mike challenges us to do all we can to live the best possible life for the longest amount of time! Talking about the importance of knowing our BMI (Body Mass Index) which not only calculates our weight but indicates our health Mike shares on the epidemic of our age - obesity - and how our lifestyles are responsible. He further shares that the biggest factor in longevity isn #39;t genetics, diet, or attitude - it #39;s aerobic capacity....in other words exercise! Now mix that with eating healthily and you #39;ve got a good chance of living long and living strong...just like God designed us to!

By: destinychurchuk

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VANCOUVER, BRITISH COLUMBIA--(Marketwire - Feb. 25, 2013) - Med BioGene Inc. (TSX VENTURE:MBI) today provided an update in regard to its ongoing litigation with Signal Genetics LLC and Respira Health LLC.

In February 2011, Signal and Respira filed a lawsuit against MBI and its commercial partner, Precision Therapeutics, Inc., in the Supreme Court of the State of New York asserting twelve causes of action against MBI. MBI continues to believe that the lawsuit is frivolous, vexatious and entirely without merit and is defending the lawsuit vigorously. MBI has received financial support from Precision to, among other things, conduct such defense (half of which is credited against future royalties that may be owed to MBI by Precision) and to cover any settlement or award of damages made against MBI, subject in all cases to certain threshold limits.

Discovery in the lawsuit has been completed and, on August 24, 2012, MBI filed with the Court a motion for partial summary judgment to dismiss Signal and Respira's claims for lost profits arising from alleged breaches of contract and the duty of good faith and fair dealing, and causes of action for negligent misrepresentation, unfair competition and unjust enrichment.

On February 20, 2013, the Court heard oral argument in connection with MBI's motion. In a Decision and Order of the same date, the Court granted MBI's motion and dismissed Signal and Respira's: (1) claims against MBI for lost profit damages arising from alleged breaches of contract and the duty of good faith and fair dealing; (2) cause of action against MBI for negligent misrepresentation; and (3) cause of action against MBI for unfair competition. No trial date has been set with respect to the remaining claims.

Erinn Broshko, MBI's Executive Chairman commented: "This decision is a significant setback for Signal and Respira. We have always believed that the lawsuit is entirely without merit and are confident that we will be successful in having the remaining claims and causes of action dismissed."

About Med BioGene

MBI is a life science company based in Vancouver, British Columbia that is currently focused on managing the license and rights to LungExpress Dx. MBI and Precision Therapeutics have partnered for the global commercialization of LungExpress Dx. For more information about Precision Therapeutics, please visit http://www.precisiontherapeutics.com. Med BioGene's common shares are listed for trading on the TSX Venture Exchange. For more information about MBI, please visit http://www.medbiogene.com.

About LungExpress Dx

LungExpress Dx is a proprietary gene expression-based test to improve upon staging for identifying those patients with early-stage non-small-cell lung cancer (NSCLC) who, following surgical removal of their tumor, are at higher and lower risks of mortality. In an initial study of patient specimens from the National Cancer Institute of Canada Clinical Trials Group JBR.10 trial, published in the Journal of Clinical Oncology, patients classified by LungExpress Dx as higher risk benefited from adjuvant chemotherapy, and those classified as lower risk did not benefit and may have experienced a detrimental effect from adjuvant chemotherapy. LungExpress Dx was subsequently validated in predicting patient mortality in four independent studies involving data from tumor specimens totaling 676 untreated early-stage NSCLC patients. LungExpress Dx is expected to provide better-informed and personalized treatment decisions to assist in the selection of patients for adjuvant chemotherapy.

Certain statements in this press release contain forward-looking statements and information ("forward-looking statements") under applicable United States and Canadian securities legislation. Words such as "anticipates", "believes", "estimates", "expects", "intends", "may", "plans", "projects", "will", "would" and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Forward looking statements include, but are not limited to, that with respect to the timing, completion and/or results of clinical trials or studies, the timing for commercialization of any products, future profits, future product revenues, future shareholder value, future operations and plans, the completion and use of proceeds from transactions or financings, the prospects for negotiating partnerships or collaborations and their timing and the expected outcomes of any litigation. These forward-looking statements are only a prediction based upon the party's current expectations, and actual events or results may differ materially. A party may not actually achieve the plans, intentions or expectations disclosed in its forward-looking statements. Forward-looking statements are subject to known and unknown risks and uncertainties and are based on uncertain assumptions that could cause a party's actual results and the timing of events to differ materially from those anticipated in such forward-looking information. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this press release. A party's forward-looking statements do not reflect the potential impact of any future partnerships, collaborations, acquisitions, mergers, dispositions, joint ventures or investments that that party may make. The outcome of litigation can be highly uncertain and you are cautioned not to place undue reliance on any forward looking statements made in respect thereof. All forward-looking statements are qualified in their entirety by this cautionary statement and a party undertakes no obligation to revise or update any forward-looking statements as a result of new information, future events or otherwise after the date of this press release, other than as required by applicable law. Each trademark, trade name or service mark of any entity appearing in this news release belongs to its holder.

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Med Biogene Provides Update on Litigation With Signal Genetics LLC and Respira Health LLC

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