Parkinson #39;s Stem Cell Therapy - Group 28 pm
BIOL 1103 Group 28 pm Stem Cell Application Assignment Sources: Euro Stem Cell research: http://www.eurostemcell.org Michael J. Fox Foundation: http://www.michaeljfox.org

By: thehaysdays

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Parkinson's Stem Cell Therapy - Group 28 pm - Video

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Now, thanks to participating veterinarians like Dr. Karen Derfuss, DVM, from Branchburg Animal Hospital, who will be conducting a new double stem cell therapy procedure on Tuesday, Feb. 26, and the procedure itself, developed by MediVet America, a new kind of treatment is available for dogs, Auggie and Chloe, and other beloved pets in the Branchburg area.

This new procedure marks a major milestone in regenerative veterinary medicine, said MediVet-America spokesman, Dr. Mike Hutchinson, D.V.M., a leading practitioner in stem cell therapy who has performed more than 400 adipose-derived stem cell treatments on dogs and cats. MediVets superior results made me a believer, and Im excited to share this news with my colleagues.

The procedure uses adult animal stem cell technology and the bodys own regenerative healing power. No embryonic stem cells are used. MediVets kit and equipment enable veterinarians to remove a sample of fat from the pet, separate stem cells from the fat, then activate and inject the cells into the affected area. The entire procedure is all done in-clinic and on the same day.

Within about one month, most animals can be removed from pain and anti-inflammatory drugs. Results show animals that had been unable to climb stairs or jump, now are walking, running and playing.

MediVet is a global leader in veterinary science, with over 1,000 clinics practicing this incredible technology in the US, Mexico, Canada and 28 other countries

About the two dogs:

Auggie is a nine year old loving beagle and a Fathers Day Gift for dad. He is suffering from hip dysplasia, which is an abnormal formation of the hip socket that, in its more severe form, can eventually cause crippling lameness and painful arthritis of the joints. Derfuss is the only doctor in the area who has been certified by MediVet America to perform this double procedure. The stem cell procedure is an affordable and non-invasive alternative to FHO (femoral head osteopathy) surgery, which was originally planned for Auggie.

Chloe is a beautiful 11 year old golden retriever who suffers from bilateral arthritic hips and long term inflammation issues. It was decided to use this new technology to treat Chloes ailments as an alternative to expensive and invasive hip replacement surgery.

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First ever double stem cell therapy procedure to be performed by Branchburg veterinarian

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Personalized Medicine in Psychiatry - Charles B. Nemeroff, MD, PhD
"Personalized Medicine in Psychiatry" presented by Charles B. Nemeroff, MD, PhD, on October 5, 2012, as part of the Dorothy C. Fuqua Lecture Series "Trailblazing in Psychiatry: Charting future paths of mental health treatments" organized and hosted by Skyland Trail.

By: Skyland Trail

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Personalized Medicine in Psychiatry - Charles B. Nemeroff, MD, PhD - Video

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Making Personalized Medicine in Oncology a Reality, with Genomic Health #39;s Kim Popovits
Cancer, whether it be breast cancer or another form, touches just about everyone, including Kim Popovits, Chairman, CEO and President at Genomic Health, Inc. Ms. Popovits talks about her inspiration for getting involved with personalized medicine in the treatment of cancer. Genomic Health is a global healthcare company that provides actionable genomic information to personalize cancer treatment decisions. For more information, visit: http://www.genomichealth.com http://www.oncotypedx.com

By: GenomicHealth

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Making Personalized Medicine in Oncology a Reality, with Genomic Health's Kim Popovits - Video

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Chris Graystone, Mary Free Bed Spinal Cord Injury Patient, uses parallel bars to walk
After suffering a spinal cord injury when attempting a polar bear plunge, Chris Graystone, has made a remarkable recovery. Determined to walk again, Chris uses the parallel bars and the assistance of a Mary Free Bed physical therapist to move his legs.

By: MaryFreeBed

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Spinal cord injury,weight lifting,Burnout
Arnar Helgi Lrusson sci 2002 T2/3 complete This video is since 2013 visit my website http://www.wix.com

By: Arnar lrusson

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Survive, Subsist, Succeed: Spinal Cord Injury Research and Outcomes
John D. Steeves, PhD: "We live in an age of rapid technological advances and scientific discoveries. From cell transplants as replacement for lost tissue to robotic devices controlled by conscious thought, many developments promise enabling solutions for disabling injuries or disorders such as spinal cord injury (SCI). But what is the status of the science and its realistic translation to help individuals living with SCI? How do we separate fact from fiction, hope from hype, desire from desperation, and near-term from long-term? What is the documented evidence for the myriad of wonders found on the internet? What should you believe and how do you become empowered to make informed decisions about where to put your energies and faith?" In this presentation, Dr. Steeves addresses these questions and provides an overview of the SCI research that has taken us from merely surviving spinal cord injuries mdash;rare before World War II mdash;to thriving with SCI and even the possibility of recovery. He brings over 30 years #39; experience as a spinal cord researcher to explain and discuss recent experimental treatments for SCI. Speaker: John D. Steeves, PhD John Penny Ryan BC Leadership Chair, Professor and Founding Director, ICORD (International Collaboration On Repair Discoveries), UBC and Vancouver Coastal Health, Vancouver, BC, Canada. Presented on May 20, 2010 at the University of Washington Medical Center by the Northwest Regional SCI System, Department of Rehabilitation Medicine ...

By: UWSpinalCordInjury

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Baylie Faella Pre-Stem Cell Therapy at Abbott Animal Hospital in Rehoboth, MA
Baylie Faella, a 7 year old Lab pre-stem cell therapy who underwent a torn ACL repair. She also suffered from atopy (allergies) and had lesions on her body.

By: Ashraf Gomaa

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Feb. 21, 2013 Cell therapy is a promising alternative to tissue and organ transplantation for diseases that are caused by death or poor functioning of cells. Considering the ethical discussions surrounding human embryonic stem cells, a lot is expected of the so-called 'induced pluripotent stem cells' (iPS cells). However, before this technique can be applied effectively, a lot of research is required into the safety and efficacy of such iPS cells. VIB scientists associated to the UGent have developed a mouse model that can advance this research to the next step.

Lieven Haenebalcke (VIB/UGent): "iPS cells have enormous therapeutic potential, but require more thorough testing before they can be used for such purposes. Using our new mouse model, we can study which mechanisms determine the identity of a cell. This knowledge is essential before we can use cell therapy for regenerative medicine."

Jody Haigh (VIB/UGent): "If we want to give cell therapy a future, then we must continue this type of research and invest in the further development of such technologies. This will result in an improved insight into cellular identity and -- in the long term -- safer options of applying iPS cells or cells derived from iPS cells in clinical studies."

Cell therapy -- replacing cells to provide a cure

Cell therapy is the replacement of lost or poorly functioning cells in patients. For example, such cell therapies could be used to repair the heart muscle after a heart attack, joints affected by arthritis, the pancreas in diabetes or the spine in certain forms of paralysis. This requires cells that are able to multiply in the laboratory and that can be converted to healthy cells of the desired cell type. Human embryonic stem cells meet these criteria, but they are ethically controversial.

iPS cells -- a promising alternative to embryonic stem cells

Shinya Yamanaka recently developed a fairly simple method to reprogram differentiated cells -- such as skin cells -- back to stem cells, so-called "induced pluripotent stem cells" (iPS cells). This earned him the Nobel Prize for Medicine in 2012 (shared with John Gurdon). These iPS cells can be generated using only 4 "reprogramming factors."

As is the case with embryonic stem cells, these iPS cells can be used to produce other cell types, such as heart muscle cells or nerve cells. They can also be cultured indefinitely and there are no ethical objections as they are not obtained from human embryos left over after IVF, but from adult individuals. Furthermore, iPS cells are obtained from the patient and this reduces the risk of rejection during therapeutic applications.

Essential research possible

Before iPS cells can be used effectively and safely as a therapy, it is essential that we gain clear insight into which molecular mechanisms determine the identity of a cell; why and how a cell develops into -- for example -- a heart muscle cell, a nerve cell or a blood cell. In order to do so, Lieven Haenebalcke and Jody Haigh have developed a mouse model that will enable them to conduct this research. They succeeded in creating iPS cells from a variety of mouse cells. Furthermore, the new model allows the investigators to replace the 4 reprogramming factors in these iPS cells efficiently with specific genes in order to create targeted different cell types, such as functional heart muscle cells.

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Cell therapy: New mouse model promises to advance research on induced pluripotent stem cells

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Feb. 21, 2013 In the first human study of its kind, researchers activated heart failure patients' stem cells with gene therapy to improve their symptoms, heart function and quality of life, according to a study in the American Heart Association journal Circulation Research.

Researchers delivered a gene that encodes a factor called SDF-1 to activate stem cells like a "homing" signal.

The study is unique because researchers introduced the "homing" factor to draw stem cells to the site of injury and enhance the body's stem cell-based repair process. Generally, researchers extract and expand the number of cells, then deliver them back to the subject.

"We believe stem cells are always trying to repair tissue, but they don't do it well -- not because we lack stem cells but, rather, the signals that regulate our stem cells are impaired," said Marc S. Penn, M.D., Ph.D., Director of Research at Summa Cardiovascular Institute in Akron, Ohio, and lead author and professor of medicine at Northeast Ohio Medical University in Rootstown, Ohio.

SDF-1 is a naturally occurring protein, secreted by cells, that guides the movement of other cells. Previous research by Penn and colleagues has shown SDF-1 activates and recruits the body's stem cells, allowing them to heal damaged tissue. However, the effect may be short-lived. For example, SDF-1 that's naturally expressed after a heart attack lasts only a week.

In the study, researchers attempted to re-establish and extend the time that SDF-1 could stimulate patients' stem cells. Study participants' average age was 66 years.

Researchers injected one of three doses of the SDF-1 gene (5mg, 15mg or 30mg) into the hearts of 17 patients with symptomatic heart failure and monitored them for up to a year. Four months after treatment, they found:

"We found 50 percent of patients receiving the two highest doses still had positive effects one year after treatment with their heart failure classification improving by at least one level," Penn said. "They still had evidence of damage, but they functioned better and were feeling better."

The findings indicate people's stem cells have the potential to induce healing without having to be taken out of the body, Penn said.

"Our study also shows gene therapy has the potential to help people heal their own hearts."

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Stem cell 'homing' signal may help treat heart failure patients

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Genetically Engineered Babies Lead to Evil Eugenics
Lord Robert Winston, Professor of Science and Society and Emeritus Professor of Fertility Studies at Imperial College, argues genetic engineering is a slippery slope that will lead to the return of the evil eugenics practices by the Nazis. Full video available for free at: fora.tv

By: ForaTv

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Genetically Engineered Babies Lead to Evil Eugenics - Video

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Public release date: 21-Feb-2013 [ | E-mail | Share ]

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 x2156 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, February 21, 2013By targeting the specific mutation that causes the hereditary neuromuscular disease myotonic dystrophy, it is possible to neutralize the mutant RNA toxicity and minimize or even eliminate the disabling symptoms of the disease. New classes of drugs called antisense oligonucleotides are being designed to achieve this. Innovative work to develop a modified antisense drug that can be administered intravenously and achieve the desired therapeutic effect is described in an article in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Nucleic Acid Therapeutics website.

Andrew Leger and coauthors from Genzyme, a Sanofi Company (Framingham, MA) added a peptide to an oligonucleotide strand designed to bind to and inactivate the mutated RNA region associated with myotonic dystrophy type 1 (DM1). The disease can affect function of the heart, central nervous system, and gastrointestinal tract, and a characteristic symptom is myotonia, in which muscles are slow to relax following contraction.

In the article "Systemic Delivery of Peptide-Linked Morpholino Oligonucleotide Neutralizes Mutant RNA Toxicity in a Mouse Model of Myotonic Dystrophy," the authors describe how the peptide is intended to enable systemic delivery of the drug, protecting it from being damaged or destroyed in the body before it can reach its target, the muscles. They report that intravenous introduction of the drug in a mouse model of DM1 led to good biodistribution of the drug, evidence that the problems previously caused by RNA toxicity were corrected, and complete elimination of myotonia in the treated mice.

"One of the greatest challenges to the therapeutic use of nucleic acids is effective and safe delivery," says Executive Editor Fintan Steele, PhD, SomaLogic, Inc., Boulder, CO. "The work of Leger and his colleagues demonstrates a potentially powerful way to meet that challenge for many diseases."

###

Nucleic Acid Therapeutics is under the editorial leadership of Co-Editors-in-Chief Bruce A. Sullenger, PhD, Duke Translational Research Institute, Duke University Medical Center, Durham, NC, and C.A. Stein, MD, PhD, City of Hope National Medical Center, Duarte, CA; and Executive Editor Fintan Steele, PhD (SomaLogic, Boulder, CO).

About the Journal

Nucleic Acid Therapeutics is an authoritative, peer-reviewed journal published bimonthly in print and online that focuses on cutting-edge basic research, therapeutic applications, and drug development using nucleic acids or related compounds to alter gene expression. Nucleic Acid Therapeutics is the Official Journal of the Oligonucleotide Therapeutics Society. Complete tables of content and a free sample issue may be viewed on the Nucleic Acid Therapeutics website.

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Drug delivery strategy eliminates myotonia symptoms in mice with myotonic dystrophy

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Part of the ancient mystery of the makeup of the modern Western dog has been solved by a team led by researchers at the University of California, Davis, School of Veterinary Medicine.

Several thousand years after dogs originated in the Middle East and Europe, some of them moved south with ancient farmers, distancing themselves from native wolf populations and developing a distinct genetic profile that is now reflected in todays canines.

These findings, based on the rate of genetic marker mutations in the dogs Y chromosome, supply the missing piece to the puzzle of when ancient dogs expanded from Southeast Asia. The study results are published online this month in the journal Molecular Biology and Evolution.

Our findings reconcile more than a decade of apparently contradictory archaeological and genetic findings on the geographic origins of the dogs, said Ben Sacks, lead study author and director of the Canid Diversity and Conservation Group in the Veterinary Genetics Laboratory at the UC Davis School of Veterinary Medicine.

Considerable archaeological evidence indicates that the first dogs appeared about 14,000 years ago in Europe and the Middle East, while dogs did not appear in Southeast Asia until about 7,000 years later. Scientists have been puzzled, though, because growing genetic evidence suggests that modern Western dogs, including modern European dogs, are derived from a Southeast Asian population of dogs that spread throughout the world.

The problem: If dogs originated in Europe, why does genetic evidence suggest that modern European dogs are originally from Southeast Asia? Sacks and his team think theyve found the answer.

Data from our study indicate that about 6,000 to 9,000 years ago, during what is known as the Neolithic age, ancient farmers brought dogs south of the Yangtze River, which runs west to east across what is now China, Sacks said.

While dogs in other parts of Eurasia continued to readily interbreed with wolves, the dogs that moved into Southeast Asia no longer lived near wolves, and so they developed a totally different evolutionary trajectory, influenced by the agriculture of Southeast Asia, he said. Those ancient dogs apparently underwent a significant evolutionary transformation in southern China that enabled them to demographically dominate and largely replace earlier western forms.

To calculate when the modern European and Southeast Asian dogs diverged, the researchers calculated the mutation rate of genetic markers on the Y chromosome in a sample of 100 Australian dingoes, a dog population known to have appeared about 4,200 years ago. Knowing the rate at which these genetic mutations occur, the researchers were able to backtrack through history and estimate the point when dogs of Eurasia and Southeast Asia parted company as being roughly 7,000 years ago.

So, in a sense, both of the original hypotheses are true: Dogs did originate in Europe and the Middle East, but modern dogs trace their ancestry most recently to the East and specifically Southeast Asia, Sacks said.

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Agriculture and parting from wolves shaped dog evolution, study finds

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biology undiscovered: episode 4 - legos of life
hey 🙂 here #39;s a short commentary for our biology class. this episode focuses on the topic of the DNA and the concept of genetics and heredity. its not much, but we did our best. special thanks to mrs. mary jean sabanal for sharing her knowledge to us 🙂 all rights reserved: One-Natomy group; II- Aristotle PACITA COMPLEX NATIONAL HIGH SCHOOL

By: Seandale Rodrichson Vista

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breast implants choosing the right size breast implant
mybreastimplants.net.au Breast Implants -- Factors to Consider Before Deciding on Having Breast Implants Not all women are gifted with the right size of breasts they want. Some have smaller that the tendency is it cannot even be noticed while others may have as big as watermelon, that #39;s just a description made by men who are so much interested with big breasted women and also by women who are, well, insecure about the size of breast they have. Sizes of breast are actually genetics. Either way, no matter how hereditary the size of breast can be passed from one generation to generation, those who are not gifted with the size of breast they want can now be able to have exactly that. With all the developments that have been made in our generation, especially in the field of science and technology, enlarging breasts is one of the simplest tasks any doctors would be happy to perform on you. Breast enlargement or otherwise known as breast augmentation surgery is a surgical placement of breast implants to increase its fullness and its projection. This is the process or method cosmetic surgeons perform to produce the size of breast their clients desired. Before any women should decide on taking breast implant procedure, they should think about some few factors first. These factors include deciding about the size of breast implant depending on their body size, the size of breast that they find attractive, and the shape of the breast implant they want. The first factor is the ...

By: Gary Eldridge

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breast implants choosing the right size breast implant - Video

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Gun Bros 2 - Universal - HD Gameplay Trailer
Gun Bros 2 by Glu Games Inc. Optimized for the iPhone 5 and iPad 3rd Gen 4th Gen. Gun Bros 2 does not support the iPhone 3GS, iPod Touch (4th generation) or iPad 1. Untold years after the first TOOL wars, the Tyrannical Oppressors Of Life have returned to finish the job. Only the Freakishly Rugged Advanced Genetics Galactic Enforcement Division (FRAGGED) agents Percy and Francis Gun stand in their way. Armed with a new array of highly advanced and ridiculously destructive weapons, the Gun Bros are once again defending the galaxy from the TOOL insurgency. It is a time to innovate and eradicate. The last conflict has left both sides scrambling to rebuild their armories. Old Xplodium mines have been reopened and even decommissioned factories are once again roaring to life as the conflict escalates. It is up to Percy and Francis to stop this threat from reemerging with an even more devastating arsenal of killing machines. The Gun Bros are back and, once again, responsible for defending the galaxy. Luckily, they #39;ve got access to a host of new gear that will help them defeat TOOL REAL-TIME MULTIPLAYER! Battle the TOOL hordes with your Gamecenter friends, head over to the all-new Endless Mode and check it out! NEW GUNS MODS! Choose from a broad range of weapons; from pistols rocket launchers to new and improved laser weapons shotguns. Collect MODS and strap them on your weapon to gain secondary, tertiary and even quaternary fire modes! Players can even unleash multiple ...

By: touchgameplay

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Gun Bros 2 - Universal - HD Gameplay Trailer - Video

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DungeCraft: Feed the Beast - Automating Bees - S3 E35
DungeCraft: Feed the Beast - Automating Bees Welcome to another episode of DungeCraft, the minecraft Feed the Beast (FTB) multiplayer survival server running Direwolf20 modpack! In this episode I go over genetics for the first line of bees up to cultivated, and then show you how to automate your apiaries. Good bee links: forum.feed-the-beast.com damnedsky.blogspot.com http://www.minecraftforum.net feed-the-beast.wikia.com My world download link, FTB pack download, and questions can be found and asked all in this thread: http://www.minecraftforum.net DungeCraft is a whitelisted Feed the Beast (FTB) server for youtubers only. If you #39;re a youtuber, and you want to join the project read the thread above to see if you qualify. Server seed: DCSeason3Seed23 Extrabiomes disabled: Snowyforest, Snowyrainforest == Other tubers on the server == Andrewpunk: http://www.youtube.com TheLMNOSteve: http://www.youtube.com Max (Thunder_Funk): http://www.youtube.com SilentMystification (Dadrewster): http://www.youtube.com Pyrostasis: http://www.youtube.com Finbar: http://www.youtube.com == Connect with me! == DG.net forums: http://www.dungeonguru.net Twitch.tv livestream: http://www.twitch.tv Facebook: http://www.facebook.com Twitter: twitter.com Minecraft / Feed the Beast (FTB) is a sandbox building game where you build impressive things from a blank world. You can play minecraft solo or on a multiplayer server. For PC and XBOX.

By: dungeongurunet

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OMICS Group-Hereditary Genetics Current research-2161-1041-1-109
OMICS Group is an Open Access publication model that enables the dissemination of research articles to the global community. Thus, all articles published under Open Access can be accessed by anyone.

By: OMICSGroup I Articles

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Obama Pledges $3 Billion to Map the Brain
The Brain Activity Map project will cost about $3 billion. But we might benefit twenty times more! Anthony shows us where the future of brain science is headed. "Obama Seeking to Boost Study of Human Brain" http://www.nytimes.com "The Obama administration is planning a decade-long scientific effort to examine the workings of the human brain and build a comprehensive map of its activity, seeking to do for the brain what the Human Genome Project did for genetics." "The Brain Activity Map Project and the Challenge of Functional Connectomics" arep.med.harvard.edu "The function of neural circuits is an emergent property that arises from the coordinated activity of large numbers of neurons. To capture this, we propose launching a large-scale, international public effort, the Brain Activity Map Project, aimed at reconstructing the full record of neural activity across complete neural circuits." "OBAMA #39;S BRAIN" http://www.newyorker.com "What will Obama #39;s proposed investment in neuroscience look like? Few details have been announced." Brain Mind Institute: bmi.epfl.ch The Blue Brain Project bluebrain.epfl.ch "Are you maximizing your DNA potential?" http://www.themakingsofme.com Image Credit © John Lund/Blend Images/Corbis DNews is a show about the science of everyday life. We post two new videos every day of the week. Watch More http://www.youtube.com Subscribe http://www.youtube.com DNews Twitter twitter.com Anthony Carboni Twitter: twitter.com Laci Green Twitter twitter.com Trace Dominguez Twitter twitter.com ...

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Strainhunters Live Thread - Smoking with Donfrom DNA @ Spannabis 2013
First dab of the expo the first day with Don From DNA genetics, when it comes to extraction, you know those guys will have some of the best taste around 😉 Check the Full report pictures and videos on Strainhunters.com

By: strainhunterslive

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Genetics Video: Brain Cancer

By: Jed Olano

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Genetics Video: Brain Cancer - Video

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Dr. Mark Green on Migraines and Genetics
Menstrual migraines, cluster headaches, basilar migraines, and tension-type headaches all can be debilitating, painful and difficult to diagnose, but the Mount Sinai Center for Headache and Pain Medicine is especially equipped with the latest technology and experience to provide diagnosis and treatment in even the most complicated cases. Treatment options include biofeedback, Botox, and other interventional procedures. Dr. Green considers all available options and medical alternatives to offer the highest level of medical treatment and care.

By: MountSinaiNY

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Ponderosa Ridge Ranch Flip Red Bluff Bull Sale
Flip is an incredible dog.He sold at Red Bluff Bull Sale 2012 for $11500. He is a full litter mate to Zeke. These 2 dogs as well as the entire litter are a prime example of genetics at their finest!!

By: Tanya williams

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Ponderosa Ridge Ranch Flip Red Bluff Bull Sale - Video

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Seconds to none- Animation with After Effects
hello everybody, this is a After Effects Animation that i have done together with my girl for the Design School Munich Bonus 2013 Project. i hope you like it. feel free to get in touch with me if you have any questions and pls check out my other videos 😉 Music by Savage Genetics (Silent Hill Remix) Directed by Marco Reinhardt and Jessica Drechsler All Rights Reserved http://www.facebook.com/eitelartworks

By: eiteldesign

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Seconds to none- Animation with After Effects - Video

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Hair loss Encyclopedia
also increased over the last five years, #39; DM Mahajan, dermatologist at Delhi #39;s Apollo Hospital. The nature of hair problems is usually varied, from hair fall, thinning and baldness to dandruff and scalp problems. Depending on the age group, some problems are more common than others. #39;The most common problem that inflicts people across all age groups is hair loss. This is a big concern for women and young males. The second most common problem is dandruff. This is usually related to climate, type of water and soap and shampoo used, Concerns about hair loss are usually more in men and at a younger age, starting as early as in their 20s #39;, Mohan Thomas, cosmetic surgeon at Mumbai #39;s Breach Candy Hospital. The reason for hair loss could be anything -- bad lifestyle, poor diet, pollution, hormones or even genetics. But stress is the big culprit behind the increasing hair woes among people, doctors say.

By: bhaskban

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Hair loss Encyclopedia - Video

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