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INTERNATIONALLY RENOWNED GYNECOLOGIC CANCER RESEARCHER JOINS OHIO STATE – Video


INTERNATIONALLY RENOWNED GYNECOLOGIC CANCER RESEARCHER JOINS OHIO STATE
COLUMBUS, Ohio -- Internationally renowned uterine cancer researcher and geneticist Paul Goodfellow will lead a new team of three researchers devoted to gynecologic oncology research at The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC -- James). "Paul #39;s expertise on the genetic and epigenetic events associated with the initiation and progression of uterine endometrial cancer makes him well-suited to lead this effort to accelerate gynecologic oncology research from basic science to Phase 1 clinical trials," says Dr. Michael Caligiuri, director of Ohio State #39;s Comprehensive Cancer Center and CEO of The James. "He is one of the latest high-level recruits that we have brought to Ohio State thanks to funds raised through Pelotonia," says Caligiuri. "We are now capitalizing on the combined clinical and research expertise at Ohio State to devise better approaches to treating endometrial cancer and breast cancer, with the ultimate goal of bringing new treatments to patients sooner." Goodfellow comes to Ohio State from Washington University School of Medicine, where he was a professor of surgery, of genetics and of obstetrics and gynecology. "As a geneticist, I #39;m interested in the genetics of tumor cells, and how gene changes influence how aggressively cancer cells will spread," says Goodfellow, who has a doctorate of biology/pediatrics from Queen #39;s University, Kingston, Canada. He also has a ...

By: OSUTheJames

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INTERNATIONALLY RENOWNED GYNECOLOGIC CANCER RESEARCHER JOINS OHIO STATE - Video

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Kate Young, RN-ACNP, Genetics Counselor – Video


Kate Young, RN-ACNP, Genetics Counselor
Kate Young has worked with CHRISTUS Schumpert #39;s Cancer Treatment Center team for nearly 20 years. She is certified in advanced oncology and is a genetic educator. Young is an alumna of the City of Hope intensive course in cancer risk assessment.

By: CHRISTUSHealthSB

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Kate Young, RN-ACNP, Genetics Counselor - Video

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1 Crazy Trick To Build Muscle – Video


1 Crazy Trick To Build Muscle
1 crazy trick to build muscle: monstermassbuilding.com Hey man, Are you tired of being skinny? Do you want to get a ripped, muscular body...FAST? Well if you do, then you found the right video! Because in this video I #39;m going to show you how my friend Johnson went from a skinny, weak 140 lbs...to being ripped and muscular at 190 lbs. The way that he made this transformation was by using 1 CRAZY muscle building trick in his workouts. I just posted a new video that shows how this trick works, and how YOU can use it to build the muscular body you #39;ve always wanted. You can watch the video at monstermassbuilding.com If you #39;re a normal guy who #39;s ready to finally build muscle, check out that video now to learn the trick. I have to warn you though -- although this #39;trick #39; helps you build muscle without spending any additional time in the gym, it DOES make your workouts way more intense. So if you #39;re a little girly-man who doesn #39;t have what it takes for extreme muscle building workouts, you should NOT watch that video. Not only will I show you the "trick" that Johnson used to build muscle in that video, I #39;ll also show you... ** The 3 BIGGEST mistakes guys make when building muscle -- which YOU may be making right now! I #39;ll show you exactly what each mistake is, and what to do instead to build the muscular body you want. ** How to gain muscle even if you #39;re genetically skinny and it #39;s putting on size is difficult for you. If you #39;re a skinny guy, I #39;ll show you what you have to do ...

By: sixpackshortcuts

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1 Crazy Trick To Build Muscle - Video

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Prenatal and Postpartum Disorders – Video


Prenatal and Postpartum Disorders
In this Video Dr. Steinberg speaks about prenatal and postpartum disorders and discusses the impact of both genetics and human relationships on the likelihood and consequences of such disorders. Dr. Carolyn Steinberg MSC,MD, FRCPC Clinical Associate Professor UBC Medical Leader Infant Child Adolescent Psychiatry Richmond Hospital, Dept of Psychiatry Richmond Early Childhood Mental Health Program

By: KidCareCanada

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Prenatal and Postpartum Disorders - Video

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Karras Farm – Awassi Fat Tail Dairy Sheep at 9mo Old – Video


Karras Farm - Awassi Fat Tail Dairy Sheep at 9mo Old
Here is a look at our Awassi fat tail sheep at nine months old. Karras Farm is the only provider of full blood Awassi dairy sheep in the United States at this time. Our imported Awassi embryos into the United States have provided new dairy sheep genetics to the USA. Thanks you for watching the video and please contact Karras Farm with any questions. Andy Karras karrasfarm.com http eastfriesiansheep.com

By: KarrasFarm

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Karras Farm - Awassi Fat Tail Dairy Sheep at 9mo Old - Video

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Savage Genetics — Silent Hill (BroStep Remix) – Video


Savage Genetics -- Silent Hill (BroStep Remix)
Remix- #1099; #1085; #1072; #1089; #1072; #1091; #1085; #1076; #1090; #1088; #1077; #1082; #1080; #1080; #1079; #1082; #1086; #1084; #1087; #1100; #1102; #1090; #1077; #1088; #1085; #1086; #1081; #1080; #1075; #1088; #1099; Silent Hill. #1048; #1085; #1092; #1086; #1088; #1084; #1072; #1094; #1080; #1103; #1086; #1073; Silint Hill: http://www.konami.com #1053; #1072; #1096; #1072; #1075; #1088; #1091; #1087; #1087; #1072; #1074; #1042; #1050;:vk.com

By: BroStepRussia

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Savage Genetics -- Silent Hill (BroStep Remix) - Video

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Star Adairis Structures. – Video


Star Adairis Structures.
The sound effects are from StarCraft, and belong to Blizzard. Names: VISERAK: Citadel Castellum Dynamo Electron Slinger Foundry Harbor Maintanance Bay Propulsion Lab Recon Terminal Rift Anchor Seismic Synthesizer Sphere Purifier Stasis Chamber Warp Relay Support Facility Temple of Hemsway KANDLIA: Blood Mound Combustion Chamber Cruor #39;s Nest Draliskan Nest GigaDraliskan Cave Flyer #39;s Tower Flyer #39;s Column Food Sac Genetics Gland DemiHive Hive Clutch Sulfra Jolt Orb Digestor Spline SAPPHIRIAN: Proton Battery Armor Facility Armor Forge Pulsar Cannon Capitol General #39;s Hall Infantry Division Marble Incinerator Praetorian Fortress Star Core StarBase Tech Center ANTARCTOSPHERE Command Base Command Bridge Command Central Core Refinery Flak Cannon Kaiser #39;s Quarters Munitions Bay Orbital Station Perimeter Platform Shockwave Cannon SkyTech Labs Space Command Uplink Star Carrier Tech Assembly Supply Unit System Supply Troop Center

By: Kaiser StratosTygo

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Star Adairis Structures. - Video

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Atossa Genetics Names Kyle Guse as Chief Financial Officer, General Counsel and Secretary

SEATTLE, WA--(Marketwire - Jan 7, 2013) - Atossa Genetics, Inc. ( NASDAQ : ATOS ), The Breast Health Company, announced today that Kyle Guse, 49, has joined the Company as Chief Financial Officer, General Counsel and Secretary. Mr. Guse brings more than 20 years of experience advising companies on public offerings, private financing, mergers and acquisitions, commercialization transactions and other corporate matters. He has completed in excess of 100 financings and other transactions totaling more than $1 billion with many life sciences and other innovative and fast growing companies.

Mr. Guse is a licensed Certified Public Accountant and lawyer.During the past year, he practiced law as a partner in the Silicon Valley office of Baker Botts LLP. From 2007 to 2012, he was a partner at McDermott Will & Emery LLP. From 1995 to 2007, Mr. Guse practiced law at Heller Ehrman LLP. He began his career in 1987 at Deloitte & Touche. Mr. Guse holds a BS in Business Administration and MBA from California State University, Sacramento, and a Juris Doctorate from Santa Clara University School of Law.

Dr. Steven C. Quay, Chairman, CEO and President, stated, "Kyle Guse is joining Atossa at a pivotal time as we accelerate the national roll-out of our ForeCYTE and ArgusCYTE Breast Health Tests and complete the development of additional tests and services. We are thrilled to have someone with Mr. Guse's financial and legal experience join us as we roll out our patented, FDA-cleared breast health products and services across the U.S."

Dr. Quay continued, "I would like to thank Chris Benjamin for his service as our interim Chief Financial Officer, including his assistance in successfully bringing us through the IPO process."

"This is a very exciting opportunity to join an emerging molecular diagnostics company focused exclusively on breast health that has developed and is selling innovative products and services," commented Mr. Guse. "I look forward to working with the Atossa team and the Board of Directors on financial strategy and execution so that Atossa can continue to commercialize its unique portfolio of products and services."

On January 4, 2013, Mr. Guse was awarded options to purchase a total of 500,000 shares of common stock of the Company, par value $0.001 per share, 95,000 of which were granted under the Company's 2010 Stock Option and Incentive Plan and 405,000 of which were granted outside the plan. The stock options have an exercise price equal to $4.11 per share, the fair market value on the grant date and vest over a four-year period with 25% vesting on his first anniversary and quarterly thereafter. The stock options were granted as an inducement to Mr. Guse's entering into employment with the Company.

For more information, please click the following link to view a video interview with Dr. Quay discussing aspects of this press release in more detail: http://client.irwebkit.com/AtossaGenetics/media. You may also sign up to receive automatic email News Alert updates there.

About Atossa Genetics, Inc.

Atossa Genetics, Inc. ( NASDAQ : ATOS ), The Breast Health Company, is based in Seattle, WA, and is focused on preventing breast cancer through the commercialization of patented, FDA-cleared diagnostic medical devices and patented, laboratory developed tests (LDT) that can detect precursors to breast cancer up to eight years before mammography, and through research and development that will permit it to commercialize treatments for pre-cancerous lesions.

The National Reference Laboratory for Breast Health (NRLBH), a wholly owned subsidiary of Atossa Genetics, Inc., is a CLIA-certified high-complexity molecular diagnostic laboratory located in Seattle, WA, that provides the patented ForeCYTE Breast Health Test, a risk assessment test for women 18 to 73 years of age akin to the Pap Smear, and the ArgusCYTE Breast Health Test, a blood test for recurrence in breast cancer survivors that provides a "liquid biopsy" for circulating cancer cells and a tailored treatment plan for patients and their caregivers.

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Atossa Genetics Names Kyle Guse as Chief Financial Officer, General Counsel and Secretary

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Bharat Book Presents: Antiviral Therapeutics – Technologies, Markets and Companies – Video


Bharat Book Presents: Antiviral Therapeutics - Technologies, Markets and Companies
For more information kindly visit on: http://www.bharatbook.com Summary This report reviews the current state-of-art of antiviral approaches including vaccines, pharmaceuticals and innovative technologies for delivery of therapeutics. The introduction starts with a practical classification of viral diseases according to their commercial importance. Various antiviral approaches are described including pharmaceuticals and molecular biological therapies such as gene therapy and RNA interference (RNAi) as well as vaccines for virus infections. Expert opinion is given about the current problems and needs in antiviral therapy. SWOT (strengths, weaknesses, opportunities and threats) analysis of antiviral approaches is presented against the background of concept of an ideal antiviral agent. A novel feature of this report is the use of nanotechnology in virology and its potential for antiviral therapeutics. Interaction of nanoparticles with viruses are described. NanoViricides are polymeric micelles, which act as nanomedicines to destroy viruses. Various methods for local as well as systemic delivery of antiviral agents and vaccines are described. Nanobiotechnology plays an important role in improving delivery of antivirals. Advantages and limitations of delivery of gene-based, antisense and RNAi antiviral therapeutics are discussed. Anti-influenza measures applicable to human as well as avian forms are described including the recent epidemic of swine flu. Resistance can develop against ...

By: Deepa Kamath

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Bharat Book Presents: Antiviral Therapeutics - Technologies, Markets and Companies - Video

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Owner hopes stem cell therapy will get dog’s life back

REHOBOTH, Mass. --

A first of its kind procedure is being performed in Massachusetts Monday. Its a stem cell therapy on a dog.

"He can't get comfortable, can't lay down, because of the pain, so he sits up and stares at the wall all night, which is tough to watch," said Bob Cook, Bubbas owner.

Cook of Taunton is talking about his 2-year-old English Bulldog Bubba, who suffers from hip dysplasia.

He said his condition has gotten worse in the last several months. After doing research, he found out about a regenerative stem cell therapy and has been hopeful.

He brought Bubba to the Abbot Animal Hospital in Rehoboth.

"Hopefully we can give these animals relief and increase quality of life and their life span as well, said Dr. Ashraf Gomaa.

Gomaa is the only doctor in our area certified by MediVet America, the company that developed this technology.

After extracting fat from Bubba, it is processed in a machine that basically breaks down the cells to get to the healthy stem cells. The cells are then injected back into Bubba into the area of concern.

"Replacing the bad cells with new cells, pretty advanced technology," Gomaa said.

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Owner hopes stem cell therapy will get dog's life back

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Stem Cell Therapy for Autism, Mumbai, India – Video


Stem Cell Therapy for Autism, Mumbai, India

By: Rajeev Ranjan

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Stem Cell Therapy for Autism, Mumbai, India - Video

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Gene Variants Linked to Alzheimer’s, Mental Illness Also Seen in Newborns

By Janice Wood Associate News Editor Reviewed by John M. Grohol, Psy.D. on January 6, 2013

Some brain changesfound in adults with common gene variants linked to disorders such as Alzheimers disease, schizophrenia, and autism can also be seen in the brain scans of newborns, according to new research.

These results suggest that prenatal brain development may be a very important influence on psychiatric risk later in life, said Rebecca C. Knickmeyer, Ph.D., lead author of the study and assistant professor ofpsychiatryat the University of North Carolina School of Medicine.

For the study, 272 infants received MRI scans shortly after birth. The DNA of each was tested for 10 common variations in seven genes that have been linked to brain structure in adults.

These genes have also been implicated in schizophrenia, bipolar disorder, autism, Alzheimers disease, anxiety disorders and depression.

For some polymorphisms, such as a variation in the APOE gene associated with Alzheimers disease, the brain changes in infants looked very similar to brain changes found in adults with the same variants, according to Knickmeyer.

This could stimulate an exciting new line of research focused on preventing onset of illness through very early intervention in at-risk individuals, she said.

But this was not true for every polymorphism included in the study, noted John H. Gilmore, M.D., senior author of the study and vice chair for research and scientific affairs in the UNC Department of Psychiatry.

For example, the study included two variants in the DISC1 gene. For one of these, known as rs821616, the infant brains looked very similar to the brains of adults. But there was no similarity between infant brains and adult brains for the other variant, rs6675281.

This suggests that the brain changes associated with this gene variant arent present at birth, but develop later in life, perhaps during puberty, Gilmore said.

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Gene Variants Linked to Alzheimer’s, Mental Illness Also Seen in Newborns

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Should We Create Children Without Fathers? – Video


Should We Create Children Without Fathers?
In a few years, having a child without a biological father may be possible for any woman who wants to go that route thanks to genetic engineering / stem cell research.

By: videoScribble

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Should We Create Children Without Fathers? - Video

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Sweet tooths #1 bigbudz genetics – Video


Sweet tooths #1 bigbudz genetics
Sweet tooths 18 week old we have messed with the genetics and turns the seeds from auto outdoor 8 week grow to a 22 week grow perfect for cfls seeds will be feminised sweet tooth #1 available online

By: TheMrbigbudz87

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Sweet tooths #1 bigbudz genetics - Video

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I’m My Own Grandpa – Complete Pedigree – Video


I #39;m My Own Grandpa - Complete Pedigree
I #39;m My Own Grandpa written by Dwight Latham and Moe Jaffe, with a Complete Pedigree. Who said Genetics is not fun...

By: rivilox

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I'm My Own Grandpa - Complete Pedigree - Video

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Dennis Drayna and the discoveries in the genetics of stuttering – Video


Dennis Drayna and the discoveries in the genetics of stuttering
Whilst I was collating information on Drayna I uncovered many pubmed publications of his research. There is a considerable number of titles including: A role for inherited metabolic deficits in persistent developmental stuttering. (Kang C, Drayna D. Mol Genet Metab. 2012 Jul 28.) Studies in a consanguineous family reveal a novel locus for stuttering on chromosome 16q. (Raza MH, Amjad R, Riazuddin S, Drayna D. Hum Genet. 2012 Feb) Analysis of mannose 6-phosphate uncovering enzyme mutations associated with persistent stuttering. (Lee WS, Kang C, Drayna D, Kornfeld S. J Biol Chem. 2011 Nov) Evaluation of the association between polymorphisms at the DRD2 locus and stuttering. (Kang C, Domingues BS, Sainz E, Domingues CE, Drayna D, Moretti-Ferreira D. J Hum Genet. 2011 Jun) Characterization of a mutation commonly associated with persistent stuttering: evidence for a founder mutation. (Fedyna A, Drayna D, Kang C. J Hum Genet. 2011 Jan) Genomewide significant linkage to stuttering on chromosome 12. (Riaz N, Steinberg S, Ahmad J, Pluzhnikov A, Riazuddin S, Cox NJ, Drayna D. Am J Hum Genet. 2005 Apr) A model system for identifying genes underlying complex traits. Drayna D, Kim UK, Coon H, Jorgenson E, Risch N, Leppert M. Cold Spring Harb Symp Quant Biol. 2003 Results of a genome-wide linkage scan for stuttering. Shugart YY, Mundorff J, Kilshaw J, Doheny K, Doan B, Wanyee J, Green ED, Drayna D. Am J Med Genet A. 2004 Jan Link to pubmed: http://www.ncbi.nlm.nih.gov

By: lololcopter123

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Dennis Drayna and the discoveries in the genetics of stuttering - Video

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Tom Wagner talks about True Potato Seed TPS – Video


Tom Wagner talks about True Potato Seed TPS
Tom Wagner on Growing and Saving True Potato Seeds (TPS). In this video Tom presents a lot of general and interesting information on potato plant genetics, as well as seed saving and cleaning techniques.Tom explains how he uses Tri-Sodium Phosphate to clean his seeds.

By: Tom Wagner

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Tom Wagner talks about True Potato Seed TPS - Video

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Ufo Object In 1400c Jesus Painting By Paolo Uccello Identifed By Gerone Wright – Video


Ufo Object In 1400c Jesus Painting By Paolo Uccello Identifed By Gerone Wright
The Ufo object within the 1400c Paolo Uccello painting is a Encrypted symbolization utilized by Uccello to demonstrate the genetic becoming of mankind and thier continued genetic bridging by a select few privied with the knowledge to practice the cult like ritual. Know that I have highlighted a few of the creatures which are responcible for genetics which ultimately lead to our current existences you google the image for yourself and realize that I #39;m on point with my findings. As expressed in the video I can through my genuine paranormal experience/encounter take you within my discoveries to any place in space and allow you to see and experience all that I can and experience, which is everything past, present, and furure. Gerone Wright

By: Geroneification

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Ufo Object In 1400c Jesus Painting By Paolo Uccello Identifed By Gerone Wright - Video

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Topping Cannabis Plants – LA Confidential / ICE – Video


Topping Cannabis Plants - LA Confidential / ICE
LA Confidential (DNA Genetics) - 24 days above soil ICE (Royal Queen Seeds) - 25 days above soil (#2) Container Size Put "Great White" Mycorrhiza in hole during germination Grow Lab GL60 Tent 2 #39;x2 #39;x5 #39;3" Hydrofarm T5 4 bulb Roots Organics Soil http://www.advancedledlights.com Filmed with Sony HDR-CX190 LEGAL GROW

By: BombyCron42

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Topping Cannabis Plants - LA Confidential / ICE - Video

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Dr. Kristy Chandler – Video


Dr. Kristy Chandler
Dr. Kristina Chandler, originally from Snellville, Georgia, graduated from the University of Georgia in 2007 with dual Bachelor of Science degrees in Biology and Genetics. She then attended the Medical College of Georgia #39;s School of Dentistry where she earned her DMD degree in 2011. While in dental school, Dr. Chandler participated in Oral Surgery and Pediatric externships at the Floyd County Public Health Department in Rome, Georgia as well as a comprehensive dentistry externship at the Ben Massell Dental Clinic in Atlanta. Throughout her four years of dental school, Dr. Chandler was honored with the Omicron Kappa Upsilon Academic Achievement Award recognizing the top 20% of the class. She was also awarded the Emile T. Fisher Foundation Scholarship, the Simon Eisenberg Scholarship, the Affinity Bank Award, and the International Congress of Oral Implantologists Pre-Doctoral Achievement Award. In addition to her academic achievements, Dr. Chandler enjoyed volunteering with the Georgia War Veterans "Dentists for Della" Project and participating in the Medical Campus Outreach Weekly Women #39;s Bible Study. Dr. Chandler is an active member of the American Dental Association, the Georgia Dental Association, and the Academy of General Dentistry. She is committed to providing the best dental care possible to her patients and continues to advance her skills by actively pursuing her continuing education. When not creating beautiful smiles, Dr. Chandler enjoys traveling, exercising ...

By: Frank Nia

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Dr. Kristy Chandler - Video

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Atossa Genetics: a focused pure play breast health testing company with huge potential to grow – Analyst Blog

Atossa Genetics: a focused pure play breast health testing company with huge potential to grow

By Grant Zeng, CFA

Atossa Genetics (NasdaqCM: ATOS ) is a medical diagnostics company focused on the prevention of breast cancer through the development and commercialization of diagnostic tests that can detect precursors to breast cancer , and through the research, development, and ultimate commercialization of treatments for pre-cancerous lesions.

To download a free copy of the full ATOS initiation report, please click here.

Atossa's diagnostic tests consist of patented medical devices cleared by the FDA that can collect fluid samples from the breast milk ducts (nipple aspirate fluid, NAF), where over 85% of breast cancers arise. These samples are processed at the Company's wholly-owned National Reference Laboratory for Breast Health , which has been certified pursuant to the Clinical Laboratory Improvement Amendments (CLIA), has been licensed in the states of California, Florida, Maryland, Rhode Island, and Washington, and is in the process of obtaining a license to accept testing samples from New York. CLIA certification is legally required to receive reimbursement from federal or state medical benefit programs, like Medicare and Medicaid, and is a practical requirement for most third-party insurance benefit programs.

Atossa's CLIA-certified laboratory examines the specimens by microscopy for the presence of normal, pre-malignant, or malignant changes as determined by cytopathology and biomarkers that distinguish "usual" ductal hyperplasia, a benign condition, from atypical ductal hyperplasia (ADH), which may lead to cancer. These cytopathological results provide patients and physicians with information about the care path that should be followed, depending on the individual risk of future cancer as determined by the results.

Additionally, Atossa is conducting research on the treatment of these pre-cancerous cells by using its patented and FDA-cleared microcatheters to deliver, directly into the milk ducts, pharmaceutical formulations that can be used to treat these pre-cancerous lesions. By using this localized delivery method, patients receive high local concentrations of these drugs at the site of the pre-cancerous lesions, potentially promoting efficacy of the treatment while limiting systemic exposure, which has the potential to lower the overall toxicity of these treatments.

Atossa is currently marketing two diagnostic tests and plans to offer two additional tests in early 2013.

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Atossa Genetics: a focused pure play breast health testing company with huge potential to grow - Analyst Blog

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Moffitt: Personalized Medicine


Moffitt: Personalized Medicine Total Cancer Care
Dr. Bill Dalton, Moffitt

By: tbpartnership

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Moffitt: Personalized Medicine

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Being Overweight Is Not a Mortality Risk

In 2009 a study from Canada reported that slightly overweight people actually were at less risk of dying than people of normal weight (see this blog, July 9, 2009). That study generated a lot of controversy, understandably. One criticism was that the study included “only” 11,000 people, all of whom were Canadians; perhaps the results would not be not be generalizable to other populations.

Now a subsequent much larger study proves the Canadian study right. The most recent study is a meta-analysis of 97 separate studies of weight versus mortality that includes over 2.9 million people. The results show quite convincingly that people who were “overweight” by current government definitions (a Body Mass Index of 25-29.9) were 6 percent less likely to die over a given time period than persons of “normal” weight (BMI 18.5-24.9).

No one is suggesting that people should gain weight just to live longer. For one thing, mortality risk goes up dramatically for persons who are severely or morbidly obese. But the data do call into question the proper definition of “normal” or ideal weight. Perhaps the definitions of normal weight, overweight, and obesity need to be shifted ever-so-slightly to the right, towards slightly higher BMIs.

We may never have a true definition of “ideal” weight, because any such definition would probably have to take into account a whole host of other factors such as physical health and even happiness. But the current data does give one food for thought when it comes to understanding the meaning and value of government definitions of ideal weights.Source:
http://humanbiologyblog.blogspot.com/2013/01/in-2009-study-from-canada-reported-that.html

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Bone Deposition in Adolescent Women Who Smoke

A recent study published in the Journal of Adolescent Health shows that the rate of bone formation in adolescent women is negatively impacted by smoking (men were not studied.) According to the study, young women aged 13-19 who smoked at least one cigarette a day had lower rates of hip and lumbar spine bone mineral density (BMD) accrual than young women who did not smoke. (The lumbar spine and hip are common areas of osteoporosis later in life.) The effect was large enough to put the smokers’ rates of bone formation about a year behind by age 19. 
Osteoporosis in older women has been linked to lower rates of bone formation during adolescence, when most bone is formed.  So it is possible that the lower rates of of bone formation seen in young women who smoke could lead to an increased risk of osteoporosis later in life.  
It is not known whether young women who smoke would “catch up” in terms of bone formation if they were to quit smoking as young adults.  Further studies would be needed to test this hypothesis.

Source:
http://humanbiologyblog.blogspot.com/2013/01/bone-deposition-in-adolescent-women-who.html

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Dopamine Receptor Gene Variant Linked To Longevity And Healthy Ageing

January 4, 2013

Connie K. Ho for redOrbit.com Your Universe Online

A study by brain researchers at the University of California, Irvine (UCI) recently found that a dopamine-receptor gene variant that is related to personality traits can also impact healthy aging. Their findings were published in the January 2 edition of The Journal of Neuroscience.

In the paper, the researchers described how the gene variant, known as DRD4 7R allele, is associated with both active personality traits and longer life expectancy. The experiment was completed by Robert Moyzis, a professor of biological chemistry at UCI, and Dr. Nora Volkow, a psychiatrist who manages the National Institute on Drug Abuse (NIDA) as well as conducts research at the Brookhaven National Laboratory (BNL).

The scientists used information from the so-called 90+Study, a project affiliated with UCIs Institute for Memory Impairments and Neurological Disorders.

While the genetic variant may not directly influence longevity, explained Moyzis in a prepared statement, it is associated with personality traits that have been shown to be important for living a longer, healthier life. Its been well documented that the more youre involved with social and physical activities, the more likely youll live longer. It could be as simple as that.

The DRD4 7R variant is a part of the dopamine system in the midbrain, a cluster of cells in the brain that assists in the exchange of signals between neurons. The dopamine system is also critical for attention as well as learning reward-driven behaviors.

The DRD4 7R allele causes a weakening of the dopamine signaling system, which in turn results in a greater reactivity of an individual to his or her environment. Moyzis and his team found that the genetic variant was present in significantly higher rates in people over the age of 90, and separate studies have independently corroborated these results by demonstrating that DRD4 7R is related to higher life expectancy in lab mice.

Researchers also believe that people who have this variant gene appear to be interested in activities that are socially, intellectually and physically stimulating. Past studies have found that both physical and mental activity is important for healthy aging, and could help limit neurodegenerative illnesses such as Alzheimers disease. However, attention-deficit/hyperactivity disorders along with addictive and risk-prone behaviors have also been connected to the variant.

For the recent study, the research team looked at genetic samples from 310 participants in the 90+ study. The studys oldest participants showed a 66 percent increase in the number of people carrying the variant gene over the younger control group of 2,902 individuals ranging from seven to 45 years of age. They discovered that the variant was more likely to be present in people who spent a greater amount of time engaging in physical activity.

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Dopamine Receptor Gene Variant Linked To Longevity And Healthy Ageing

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