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Surprising genetic link between kidney defects and neurodevelopmental disorders in kids

Public release date: 15-Nov-2012 [ | E-mail | Share ]

Contact: Karin Eskenazi ket2116@columbia.edu 212-342-0508 Columbia University Medical Center

New York, NY (November 15, 2012) About 10 percent of kids born with kidney defects have large alterations in their genomes known to be linked with neurodevelopmental delay and mental illness, a new study by Columbia University Medical Center (CUMC) researchers has shown.

The study was published today in the online edition of the American Journal of Human Genetics.

Congenital defects of the kidney and urinary tract account for nearly 25 percent of all birth defects in the US and are present in about 1 in every 200 births. Eventually, an evaluation for genomic alterations will be part of the standard clinical workup. Patients with congenital kidney diseasewho are currently lumped into one categorywill be placed in subgroups based on their genetic mutations and receive a more precise diagnosis.

"This changes the way we should handle these kids," said kidney specialist Ali Gharavi, MD, associate professor of medicine at CUMC, associate director of the Division of Nephrology, and an internist and nephrologist at NewYork-Presbyterian Hospital.

"If a physician sees a child with a kidney malformation, that is a warning sign that the child has a genomic disorder that should be looked at immediately because of the risk of neurodevelopmental delay or mental illness later in life," he said. "This is a major opportunity for personalizing medical care. As we learn which therapies work best for each subgroup, the underlying genetic defect of the patient will dictate what approach to take."

The current study was the result of a large collaborative effort of CUMC and other medical centers in the US, Italy, Poland, Croatia, Macedonia, and the Czech Republic. It was led by Dr. Gharavi and his colleague Simone Sanna-Cherchi, MD, an associate research scientist in CUMC's Department of Medicine.

Until now, no studies have linked congenital kidney disease with neurodevelopmental disorders.

"If you talk to clinicians, they tell you that some of these kids behave differently," Dr. Sanna-Cherchi said. "There has been a general assumption, though, that behavioral or cognitive issues in children with chronic illnesses such as kidney disease stem from the child's difficulty in coping with the illness. Our study suggests that in some cases, neurodevelopmental issues may be attributable to an underlying genomic disorder, not the kidney disease."

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Surprising genetic link between kidney defects and neurodevelopmental disorders in kids

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Genetic Link Found In Children With Kidney Defects And Neurodevelopmental Disorders

Editor's Choice Main Category: Urology / Nephrology Also Included In: Pediatrics / Children's Health;Genetics Article Date: 16 Nov 2012 - 10:00 PST

Current ratings for: Genetic Link Found In Children With Kidney Defects And Neurodevelopmental Disorders

Around 10 percent of kids with kidney defects have these mutations in their genomes, also known to be associated with mental illness and neurodevelopmental delay.

Congenital urinary tract and kidney defects make up about 25 percent of all birth defects in the United States and are found in one in every 200 births.

At last, an analysis for genomic alterations will be included in standard clinical workup. Patients who have congenital kidney disorder, presently included in one group, will be put into subcategories according to their genetic mutations, resulting in a more specific diagnosis.

Kidney specialist Ali Gharavi, MD, associate professor of medicine at CUMC, associate director of the Division of Nephrology, and an internist and nephrologist at NewYork-Presbyterian Hospital says:

This study was a broad collaboration of CUMC and other medical centers worldwide. Up until this point, no studies have successfully connected congenital kidney disease with neurodevelopmental disorders.

Simone Sanna-Cherchi, MD, an associate research scientist in CUMC's Department of Medicine explains:

Nearly 20 percent of kidney defects come from big DNA mutations. The mutations identified by Drs. Gharavi and Sanna-Cherchi and their team, are in a class of mutations known as copy number variations (CNVs).

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Genetic Link Found In Children With Kidney Defects And Neurodevelopmental Disorders

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New genetic test provides precise, yet hazy results

A patient receives an ultrasound before a new genetic test for potential fetus abnormalities Oct. 4 at obstetrician Susan Klugman's office in Scarsdale, N.Y.(Photo: Carucha L. Meuse, The (Westchester, N.Y.) Journal News)

WESTCHESTER, N. Y. -- A new test, called chromosomal microarray technology, is providing doctors and prospective parents with more information than ever before about the genetic makeup of a baby still in the womb.

But what that knowledge actually means is not always clear, causing confusion and anxiety for parents and physicians.

Michelle Catalano had no reason to think her fourth baby wouldn't be born as healthy as her other three.

But because the Eastchester, N.Y., resident was 36 -- a year into the territory obstetricians ominously describe as "advanced maternal age" -- she was given the option of using the new technology to test whether her baby was developing free of genetic defects that could signal trouble.

"It's an evolving technology," said David Kronn, chief of medical genetics at Maria Fareri Children's Hospital at Westchester Medical Center in Valhalla, N.Y. The results, he said, aren't always cut and dried.

Susan Klugman, an obstetrician in Larchmont and Yonkers, N.Y., and 300 of her patients recently took part in a nationwide study of chromosomal microarray technology to determine how effective the method is.

"This zooms down and looks at the specific genetic material in the chromosomes to make sure nothing is missing or nothing is extra," said Klugman, director of reproductive genetics at Montefiore Medical Center and an associate professor at Albert Einstein College of Medicine.

Initial results of the study submitted early this year at the Society for Maternal-Fetal Medicine showed that prenatal chromosomal microarray technology can detect more genetic abnormalities than current methods.

Klugman now offers the test to select patients in her practice.

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REVENGE IS SWEET (The Hidden: Source)
Hey Guys! Shady Here! Download Here: http://www.hidden-source.com Thanks for watching and if you don #39;t know what the hidden is... "In the early 1950s human genetics experimentation was taking its first, tentative steps. Amongst many other black projects, a team of British scientists working at an Infinitum Research experimental station stumbled across some remarkable phenomena involving DNA manipulation. This led to deeper research with dangerously unpredictable results, often leading to human patients losing their lives in irresponsible and immoral experiments. Time passed on, and by the mid 1990s the failure rate of the experiments had been reduced from 75% to a mere 15%, enough for Infinitum to move onto the next stage: Biological Light Refraction. The British team were hoping to unravel the possibilities of light manipulation to create the perfect covert military agent. Early into the new millennium, due to a gross miscalculation, a series of tests on Subject 617 led to a massive synaptic trauma leaving the patient with multiple genetic anomalies. The subject was left in constant pain and with unstable DNA. The subject escaped captivity, killing anyone that got in its way. The IRIS (Infinitum Research Interception Squad) team have been deployed to return the subject to a maximum security Infinitum Research facility for further study and dissection. The entire project was considered a failure: all funding ceased and development was discontinued while all records and traces of ...From:TheShadesofPALEViews:27 1ratingsTime:03:47More inGaming

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Handbook On Immunosenescence
ll4.me Handbook On Immunosenescence 1. Immunosenescence.- 2. Methods and models for studying immunosenescence.- 3. Cellular immunosenescence. 3.1 T cells. 3.2. B cells. 3.3 Neutrophils. 3.4 Antigen presenting cells. 3.5 NK and NKT cells. 3.6. Stem cells. 3.7. Genetics.- 4. Mechanisms4.1. Receptors and signal transduction. 4.2 Mitochondria. 4.3 Proteasome. 4.4 Cytokines. 4.5 Neuro-endocrine-immune Network. 4.6 Thymus. 4.7. Inflammation.- 5. Clinical relevance in disease states. 5.1 Infection. 5.2 Autoimmunity. 5.3 Cancer. 5.4 Metabolic syndrome. 5.5. Neurodegenerative diseases. 5.6 Frailty. 5.7. Osteoporosis.- 6. Modulation. 6.1 Nutrition. 6.2. Lipids. 6.3. Vaccination. 6.4. Can interventions to influence immunosenescence succeed? Subject Index. EAN/ISBN : 9781402090639 Publisher(s): Springer Netherlands Discussed keywords: Immunologie Format: ePub/PDF Author(s): Fulop, Tamas - Franceschi, Claudio - Hirokawa, Katsuiku 1. Immunosenescence.- 2. Methods and models for studying immunosenescence.- 3. Cellular immunosenescence. 3.1 T cells. 3.2. B cells. 3.3 Neutrophils. 3.4 Antigen presenting cells. 3.5 NK and NKT cellsFrom:aaronrogers9865Views:0 0ratingsTime:00:16More inPeople Blogs

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Molecular Diagnostics – Video


Molecular Diagnostics
ll4.me Molecular Diagnostics Key Features #65533; Contains state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders #65533; Includes in-depth discussion of ethical and safety considerations #65533; Identifies genetically modified organisms (GMO #39;s) #65533; Covers forensic analysis and every-day issues in a diagnostic laboratoryDescriptionThe second edition of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited disease. The book delves further into the principle and brief description of the technique, followed by examples from the authors #39; own expertise. Contributors to the 2/e are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. Molecular Diagnostics, 2/e , is a needed resource for graduate students, researchers, physicians and practicing scientists in molecular genetics; professionals from similar backgrounds working in diagnostic laboratories in academia or industry, as well as, academic institutions and hospital libraries.RELATED TITLES:Trent/Molecular Medicine, April 2005,$79.95, 0-12-699057-3 Innis (1999) PCR Applications, HB, $89.95,0-12-372185-7, PB, $66.95,Key Features:*Deals exclusively with the currently used molecular biology techniques to identify the underlying molecular defect of inherited diseases*Includes ...From:melissafudge9865Views:0 0ratingsTime:00:13More inPeople Blogs

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Wes Jackson, President of The Land Institute, was born in 1936 on a farm near Topeka, Kansas. After attending Kansas Wesleyan (BA Biology, 1958), he studied botany (MA University of Kansas, 1960) and genetics (Ph.D. North Carolina State University, 1967). He was a professor of biology at Kansas Wesleyan and later established the Environmental Studies department at California State University, Sacramento, where he became a tenured full professor. He resigned that position in 1976 and returned to Kansas to found The Land Institute. Dr. Jackson #39;s writings include both papers and books. His most recent works, Nature as Measure (2011) and Consulting the Genius of the Place: An Ecological Approach to a New Agriculture (2010), were both published by Counterpoint Press. The Virtues of Ignorance: Complexity, Sustainability, and the Limits of Knowledge (2008) and Rooted in the Land: Essays on Community and Place (1996), were co-edited with William Vitek. Becoming Native to This Place, 1994, sketches his vision for the resettlement of America #39;s rural communities. Altars of Unhewn Stone appeared in 1987 and Meeting the Expectations of the Land, edited with Wendell Berry and Bruce Colman, was published in 1984. New Roots for Agriculture, 1980, outlines the basis for the agricultural research at The Land Institute. The work of The Land Institute has been featured extensively in the popular media including The Atlantic Monthly, Audubon, National Geographic, Time Magazine, The MacNeil ...From:TEDxTalksViews:0 0ratingsTime:18:21More inScience Technology

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Obamacare


Obamacare Origin of Nazi Holocaust - Eugenics / Euthanesia
Few may realize it, but the Holocaust started in the national healthcare system of Germany with a project called the T4 program. It began with the idea that the distribution of healthcare should be based on the welfare of society, according to Government priorities. Hitler ordered the hospitals and mental institutions to euthanize hundreds of thousands of the handicapped and mentally ill, in order to save money. In any universal healthcare system the Government will be deciding at some level, who gets healthcare and who doesn #39;t, that is, who lives and who dies. Much of the early work in Eugenics was done in the United States and Hitler was inspired by the work by of American scientists. Eugenics is the idea that Government can improve that health of the population by making decisions that change the genetics of the population. The German government decided that the Jewish race is genetically inferior and their genes should be eliminated from the population. Many of the techniques used in the extermination of the Jews were developed in the hospitals of the German universal healthcare system. Following is an excerpt of a documentary on the Nazi T4 program. Obamacare Eugenics -- Why the Government should NOT Control Healthcare! stop-obama-now.netFrom:SoNSanDiegoViews:73 4ratingsTime:03:37More inNews Politics

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Quark Expeditions: Q A with Dr. Tom Hart, Penguinologist - Part 2
Part 2 of our webinar with Tom Hart, Penguinologist. Apologies for the low audio. Dr. Tom Hart will be part of the Expert In Residence program on the following Quark Expeditions voyages: November-22-30 2012 Introduction to Antarctica: The White Continent November-30-Dec-09 2012 Antarctic Explorer: The Classic Adventure December-09-18 2012 Antarctic Explorer: The Classic Adventure December-18-27 2012 Antarctic Explorer: The Classic Adventure December-27 2012- January-14 2013 Falklands, South Georgia and Antarctica: Explorers and Kings About Dr. Tom Hart: Tom runs the Penguin Lifelines project at Oxford University and the Zoological Society of London, through which he monitors Antarctic wildlife using camera trapping, volunteer photos and population genetics. Tom #39;s PhD at Imperial College and the British Antarctic Survey investigated penguin foraging behavior around South Georgia. He loves the world #39;s cold places and is passionate about protecting them. Tom loves all penguins, but particularly Macaroni Penguins, as they have the most attitude.From:QuarkExpeditionsViews:2 0ratingsTime:07:09More inPets Animals

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21 y/o Natural Bodybuilder – Polska Genetics and Nikola Gojani: Offseason Posing Update – Video


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*SUBSCRIBE AND LIKE* Please check out my Facebook Page for Updates and News!! http://www.facebook.com http://www.facebook.com Intro by. http://www.youtube.com Music produced by: http://www.myspace.comFrom:mousch66Views:2078 74ratingsTime:07:44More inSports

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Joesph Salama – author of "The Paleo Miracle", a book showing that food is medicine – Video


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From three weeks into his paleo transformation, Joseph Salama was so inspired by his health and happiness level that he began sharing it with his friends and family - with smashing success, helping his mother with her type II diabetes and his father with his Parkinson #39;s. By the end of ten months, he had over 80 converts under his belt - all of whom reported improved health, weight loss, and more energy and vigor than they had felt in years. But that wasn #39;t enough. So he sought out and contacted hundreds of others who have transformed, and selected the best stories to share with the rest of the world in a book, "The Paleo Miracle, 50 stories of change and found health. When he isn #39;t working on paleo books, Joseph is busy being a father, a trial attorney, and a mediator in the San Francisco Bay Area, and sits on the Board of Directors for several non-profit organizations. What is the Paleo Diet and why The Paleo Miracle book? Do you think that weight gain and disease are simply a function of age and genetics? Do you wonder why, despite eating a whole-grain, low-fat diet and putting in countless hours of exercise, you aren #39;t getting any thinner? Most importantly: Why do you eat the way you do? Because someone else told you that it is healthy? In the paleo community, we believe that FOOD IS MEDICINE. We have either eliminated all symptoms of, or dramatically improved, the diseases we had by eating REAL food - diseases like diabetes, heart disease, ADHD, Crohn #39;s, and many ...From:Bill VickViews:4 1ratingsTime:13:58More inPeople Blogs

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These ladies possess some of the best Genetics in the Beef Industry. They are sired by Conneally Angus Bulls out of Commercial Angus cows they are bred to Stevenson Basin Angus Bulls. They will start calving the first week of Feb. and should be calved out in 6-8 weeks. Clay 9795416703From:cowboysales1Views:3 0ratingsTime:01:20More inPets Animals

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Origin of so called Caucasian Race – Video


Origin of so called Caucasian Race
Similarities = Same Proto-Indo-European Language Group, Same Spinal Facial Structure, Skull Structure, Social and Linguistic Similiraties between DESI (south Asian, ie Pakistan, India, Sri Lanka, Bangladesh) and Northern Europeans... South Europeans from Spain, Italy, and France, are not strictly Aryans, Because are mixed between The Albino Desi #39;s and Semetics... whilst DESI #39;s are seperate from Arab and are a pure genetic group. East Asians geographically have a harder place to mix genetics,.. white, black, big brother, indian, people, albino, science, origin, life, environment, home, racism, race, nation, entertainment, televisino, culture, celebs, hollywood, society, tech, gadget, android, google, iphone, albinism. and more... Its not racist its actually the opposite of racism, but its definatly an eye opener South Europeans are NOT #65279; linked with North Europeans... South Europeans are semetic, with Afro-Asiatic mix... North are Pure INDO-europeans South Europeans genetics mutated #65279; from African Albinos.... Semetic North European genetics mutated from Indian Albinos ...... Indo-European.From:JayEther9Views:0 0ratingsTime:05:26More inEducation

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Origin of so called Caucasian Race - Video

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Gregory Stock – Aging: The Disease, The Cure, The Implications – Video


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Gregory Stock is a biophysicist, best-selling author, biotech entrepreneur, and the director of the Program on Medicine, Technology and Society at UCLA #39;s School of Medicine. He has written extensively on the implications for society, medicine and business of the human genome project and associated developments in molecular genetics and bioinformatics. His interests lie in the scientific and evolutionary as well as ethical, social and political implications of today #39;s revolutions in the life sciences and in information technology and computers. He has dealt with topics relating to privacy issues in healthcare and genomics; advances in reproductive biology and embryo screening; future possibilities in human germline engineering and anti-aging interventions; and scenarios of future human evolution. Stock #39;s speeches, writings and positions reflect a vision of pragmatism if not enthusiasm about adapting to the profound and difficult shifts these new technologies will bring and avoiding unnecessary delay in the development of new therapeutics and medical and biological interventions emerging from progress in the life sciences. Stock also is the CEO of Signum Biosciences, a biotech company developing therapeutics for Alzheimer #39;s and other diseases as well as health and wellness agents. He sits on the editorial board of the American Journal of Bioethics and is in the department of Pediatrics at the UCLA School of Medicine. He is a member of the Board of Directors of Napo ...From:Jeriaska JeriaskaViews:0 0ratingsTime:20:45More inEntertainment

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Bernard Siegel – Aging: The Disease, The Cure, The Implications – Video


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Bernard Siegel is the full-time Executive Director of the nonprofit Genetics Policy Institute (GPI) based in Palm Beach Gardens, Florida. He received his undergraduate and law degrees from the University of Miami (BA 1972, JD 1975). He is a member of the Florida Bar since 1975. In 2002, Mr. Siegel filed the landmark case seeking a guardian for the alleged clone, "Baby Eve." The case was widely credited for exposing Clonaid , the so-called "human cloning company" as a sham. In 2003, he traded his 30-year courtroom career to found GPI, which leads the global cause in support of stem cell research. He is a recognized policy expert relating to stem cell research, regenerative medicine and cloning. Working with the world #39;s leading stem cell researchers, Mr. Siegel played a pivotal role in protecting the research in the United Nations, which was under the threat of being banned by world treaty. He also works with grassroots activists throughout the United States, educating lawmakers and formulating effective strategies supporting research for cures. Mr. Siegel serves on the board of directors of Americans for Cures and on the advisory boards of the Sabrina Cohen Foundation for Stem Cell Research, The Brooke Ellison Project and Genomics Education Institute. He is a member of the American Society for Bioethics + Humanities. He is a member of the International Society for Stem Cell Research and serves as the co-chair of the ISSCR Governmental Affairs Committee. Mr. Siegel has been ...From:Jeriaska JeriaskaViews:0 0ratingsTime:18:57More inEducation

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Perry asks us to discuss our reactions to some incidents of transphobia... by every definition have a certainly experienced transphobia, however recently i have begun a stance of non-participation in transphobic situations. i continue simply being. the reason people become trans has everything to do with genetics. there has, for nearly 40 or so years now, been scientifically validated evidence of a region of the brain that in the brains of male identifying individuals is shaped one way, and in female identifying individuals is shaped a different way. in other words science has discovered a part of the brain that determines gender. additionally there is a segment of the brain that determines sexual attractions and how or bodies react to different pheromones, which is not necessarily gender specific. for me knowing that down to my DNA i am a transsexual and resistance is futile is actually really comforting.From:TrannystarGalacticaViews:0 0ratingsTime:04:46More inEducation

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Genetics study into lung condition

British scientists are to conduct the world's largest study of the genetics behind the lung condition chronic obstructive pulmonary disease (COPD).

Data from 50,000 individuals will be used to determine genetic variants linked to susceptibility to COPD.

In particular, researchers want to see how COPD genes relate to smoking, a major risk factor for the disease.

COPD comprises a group of disorders including chronic bronchitis and emphysema. Each year it affects around 900,000 people in the UK, causes 30,000 deaths, and costs the NHS 500 million.

Details of the new study are being released to mark World COPD Day.

The scientists will draw on the resources of the new UK Biobank, which holds genetic samples as well as health and lifestyle information on half a million volunteers.

Lead researcher Professor Ian Hall, dean of Nottingham Medical School, said: "We currently know very little about why there is such a wide difference in lung health even among smokers. It may have something to do with genetics so we're extremely excited about using the unique resource of the UK Biobank to test this theory."

The work is being funded by the Medical Research Council (MRC). Professor David Lomas, chair of the MRC Population and Systems Medicine Board, said: "We know that smoking is unhealthy for anyone but we know little about why the lungs of most smokers are seriously affected, while those of some seem to stay relatively healthy.

"If we knew more about the genetics that cause this variation we would be better able to direct treatments to those who are most at risk and have an increased chance of developing drugs to target this type of lung disease."

Scientists from the University of Nottingham, the University of Leicester, and St George's, University of London, are taking part in the research.

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Lucid PR: COBB-VANTRESS AND HENDRIX GENETICS EXTEND R&D PARTNERSHIP

WASHINGTON--(BUSINESS WIRE)--

Affordable and higher quality food will result from new genetic advances inspired by a unique industry collaboration. Two of the worlds largest animal breeding companies aim to achieve further breakthroughs in the field of genomics during the next three years of a joint development agreement (JDA).

Arkansas-based Cobb-Vantress Inc. and Hendrix Genetics B.V. which is headquartered in Boxmeer in the Netherlands initially set up the JDA in 2008 to share and promote expertise, particularly in the fast-growing field of genomics. Already new genomic selection tools have been discovered and developed, such as the cutting-edge SNP Chip for chickens. This is a glass slide that can analyze between 60,000 and 1 million variations in DNA sequences - or Single Nucleotide Polymorphisms (SNPs) - which act as biological markers and help scientists locate a range of genes associated with disease.

The extended agreement will intensify efforts to develop new tools and discover fresh insights into animal genomics in order to improve breeding programs and help increase world food production.

Dr. Gerard Albers, head of research and technology at Hendrix Genetics, said: This is like two renowned chefs sharing recipes, swapping thoughts and ideas on how to create a perfect dish. There are many ways to create this dish, many ingredients that can be used, and with shared views we are able to come closer to this perfect dish.

The collaboration is the biggest within the animal breeding industry and will produce animals that are more productive, less susceptible to disease and at reduced cost, therefore helping to tackle global food shortages. According to the United Nations World Food Program there are 870 million undernourished people in the world today.

The JDA will also strengthen Cobbs leading position in broiler breeding and Hendrix Genetics renowned role in layer hen, turkey, pig and aquaculture genetics, while enabling the two companies to further explore joint venture business opportunities.

Cobb-Vantress is the worlds leading supplier of broiler breeding stock and technical expertise for the chicken meat industry. It has about 2,500 employees and serves the industry in more than 90 countries.

Hendrix Genetics has nearly 2,400 employees worldwide and operations in 24 countries and provides expertise and resources to producers in more than 100 countries.

Jerry Moye, president of Cobb-Vantress, said: The joint efforts of the Hendrix and Cobb R&D teams have provided valuable knowledge for both of our companies. Cobb is excited to continue our partnership with Hendrix Genetics. We look forward to discovering what opportunities may be in our future.

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Lucid PR: COBB-VANTRESS AND HENDRIX GENETICS EXTEND R&D PARTNERSHIP

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Atossa Genetics, Inc. Announces Closing of Initial Public Offering

SEATTLE, WA--(Marketwire - Nov 14, 2012) - Atossa Genetics, Inc. ( NASDAQ : ATOS ) announced today the closing of its initial public offering of 800,000 shares of its common stock at an initial public offering price of $5.00 per share. Atossa Genetics' common stock is traded on the NASDAQ Capital Market under the trading symbol "ATOS."

Dawson James Securities, Inc. acted as the sole book-running manager and lead underwriter for this offering along with ViewTrade Securities, Inc. and Paulson Investment Company.

A copy of the final prospectus relating to the offering may be obtained by contacting Monique Maclaren of Dawson James Securities, Inc. at (561) 391-5555 or by emailing mmaclaren@dawsonjames.com or by standard mail at 925 S. Federal Highway, Suite 600, Boca Raton, FL 33432. You may also obtain these documents for free by visiting EDGAR on the SEC's website at http://www.sec.gov.

A registration statement relating to these securities was declared effective by the Securities and Exchange Commission on November 7, 2012. This offering was made solely by means of a prospectus. This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or other jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

About Atossa Genetics, Inc.

Atossa Genetics, Inc., The Breast Health Company, is based in Seattle, Washington, and is focused on the prevention of breast cancer through the commercialization of diagnostic medical devices and tests that can detect precursors to breast cancer, and through research and development that will permit it to commercialize treatments for pre-cancerous lesions.

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Atossa Genetics, Inc. Announces Closing of Initial Public Offering

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Interleukin Genetics Reports Third Quarter 2012 Financial Results

WALTHAM, Mass.--(BUSINESS WIRE)--

Interleukin Genetics,Inc. (ILIU) today announced financial and operational results for the third quarter ended September 30, 2012.

Total revenue for the three months ended September 30, 2012 was $420,000, compared to $765,000 for the same period in the prior year. The decrease was primarily attributable to a decrease in genetic tests returned and processed and lower sales of our Inherent Health brand of genetic tests through our Merchant Network and Channel Partner Agreement with Amway Global. Cash received from genetic test sales is reflected as deferred revenue until the test report is issued. Deferred revenue increased $146,000 to $971,000 at September 30, 2012 as compared to December 31, 2011.

Research and development expenses were $246,000 for the three months ended September 30, 2012, compared to $325,000 for the same period in the prior year. The decrease was primarily attributable to lower consulting costs partially offset by increased compensation costs.

Selling, general, and administrative expenses were $1.0 million for the three months ended September 30, 2012, compared to $1.1 million for the same period in the prior year. The decrease was primarily attributable to lower patent related legal fees, insurance, consulting and sales commissions paid to Amway partially offset by increased professional fees and employee separation costs.

The Company reported a net loss of $1.3 million, or $(.03) per basic and diluted common share, for the third quarter of 2012 compared to $1.1 million, or $(.03) per basic and diluted common share, for the same period in 2011. On September 30, 2012, the Company had cash and cash equivalents of $2.5 million.

The Company expects that its current and anticipated financial resources are adequate to maintain current and planned operations at least through November 30, 2012, the due date of its credit facility with Pyxis Innovations, Inc., and through March 31, 2013 if the due date of the credit facility is extended. Management is in discussions with Pyxis to extend this due date. The Companys independent registered public accounting firm has included an explanatory paragraph in their opinion in connection with the 2011 audit, relating to the Company's ability to continue as a going concern.

We are encouraged by the positive top line results received from the University of Michigan study that employed our PST test. The results of the study should provide the evidence to support broader use of this test to both improve preventive dental care and favorably influence healthcare costs. We are now focused on ramping up the broad commercialization of our PST genetic test for improved management of dental patients, said Kenneth S. Kornman, Chief Executive Officer of Interleukin Genetics.

Conference Call and Webcast Information

Interleukin Genetics will host a live conference call and webcast today at 4:30 p.m. EST to review the Companys new business developments and third quarter financial results. To access the live call, dial 877-324-1976 (domestic) or 631-291-4550 (international). The live webcast and replay access will be available on the Investors section of the Companys Website at: http://www.ilgenetics.com.

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Interleukin Genetics Reports Third Quarter 2012 Financial Results

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Myriad Genetics to Present at the Piper Jaffray Healthcare Conference

SALT LAKE CITY, Nov. 15, 2012 (GLOBE NEWSWIRE) -- Myriad Genetics, Inc. (MYGN) announced today that Peter D. Meldrum, President and CEO, is scheduled to present at the Piper Jaffray Healthcare Conference, at 4:00 p.m. Eastern Time on Tuesday, November 27, 2012. The conference is being held at The New York Palace in New York, New York.

The presentation will be available to interested parties through a live webcast accessible on the investor relations section of Myriad's website at http://www.myriad.com.

About Myriad Genetics

Myriad Genetics is a leading molecular diagnostic company dedicated to making a difference in patients' lives through the discovery and commercialization of transformative tests to assess a person's risk of developing disease, guide treatment decisions and assess risk of disease progression and recurrence. Myriad's portfolio of molecular diagnostic tests are based on an understanding of the role genes play in human disease and were developed with a commitment to improving an individual's decision making process for monitoring and treating disease. Myriad is focused on strategic directives to introduce new products, including companion diagnostics, as well as expanding internationally. For more information on how Myriad is making a difference, please visit the Company's website: http://www.myriad.com

Myriad, the Myriad logo, BRACAnalysis, Colaris, Colaris AP, Melaris, TheraGuide, Prezeon, OnDose, Panexia and Prolaris are trademarks or registered trademarks of Myriad Genetics, Inc. in the United States and foreign countries. MYGN-G

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Myriad Genetics to Present at the Piper Jaffray Healthcare Conference

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Advocation against Gene Therapy – Video


Advocation against Gene Therapy
Antony Vorobyov ENG 111 NK Ms. Soares 11-14-2011From:Antony VorobyovViews:1 0ratingsTime:05:17More inFilm Animation

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Advocation against Gene Therapy - Video

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Essentials Of Genomic And Personalized Medicine – Video


Essentials Of Genomic And Personalized Medicine
ll4.me Essentials Of Genomic And Personalized Medicine Derived from the comprehensive two-volume set, Genomic and Personalized Medicine also edited by Drs. Willard and Ginsburg, this work serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing one of the most promising avenues for advances in diagnosis, prevention and treatment of human disease. From principles, methodology and translational approaches to genome discoveries and clinical applications, Essentials ofGenomic and Personalized Medicine will be a valuable resource for various professionals and students across medical disciplines, including human genetics and genomics, oncology, neuroscience, gene therapy, molecular medicine, pharmacology, and biomedical sciences. Updates with regard to diagnostic testing, pharmacogenetics, predicting disease susceptibility, and other important research components as well as chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, present this book as an essential tool for a variety of professionals and students who are endeavouring into the developing the diverse and practical field of genomic and personalized medicine.* Full color throughout* Includes contributions on genetic counselling, ethical, legal/regulatory, and social issues related to the practice of genomic medicine from leaders in the field * Introductory chapter ...From:melissawatkins987Views:0 0ratingsTime:00:10More inPeople Blogs

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Essentials Of Genomic And Personalized Medicine - Video

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Clinical Pharmacology: Current Topics And Case Studies – Video


Clinical Pharmacology: Current Topics And Case Studies
ll4.me Clinical Pharmacology: Current Topics And Case Studies 1. Introduction- The discipline of Clinical Pharmacology- Markus Mller; Professor of Clinical Pharmacology, Vienna, Austria- Example: EACPT position paper- Current issues in drug development- Markus Mller; Professor of Clinical Pharmacology, Vienna, Austria- Example: Pfizer- Current issues in drug regulation- Marcus Mllner / Hans Georg Eichler; Professor and Head, Austrian Medicines Agency AGES, Vienna, Austria / Professor and Senior Medical Officer, EMEA, London, UK- Example: EMEA - Current issues in drug reimbursement- Anna Bucsics; Medical Director, Austrian Board of Social Security Institutions- Example: comparative effectiveness - 2. Clinical Trials- Ethics of clinical research- Ernst Singer; Professor and Head, Ethics Committee, Medical University Vienna, Austria- Example: Nrnberg, Helsinki, Belmont- GCP, Scientific misconduct- Brigitte Blchl-Daum; Professor of Clinical Pharmacology, Vienna, Austria- Example: Tuskegee, Vioxx- Phases of drug development, first in man studies- Bernd Jilma; Professor of Clinical Pharmacology, Vienna, Austria- Example: Tegenero- Clinical trials interventional studies- Michael Wolzt; Professor of Internal Medicine, Vienna, Austria- Example: CAST- Clinical trials observational studies- Ch. Male / H. Herkner; Professor of Pediatrics, Vienna, Austria/ Professor of Internal Medicine, Vienna, Austria- Example: CDC "Outbreak"- Pharmacokinetics / Pharmacodynamics- Hartmut Derendorf ...From:meganhorne326Views:1 0ratingsTime:00:12More inPeople Blogs

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Clinical Pharmacology: Current Topics And Case Studies - Video

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