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Study sheds light on genetic ‘clock’ in embryonic cells

Public release date: 13-Nov-2012 [ | E-mail | Share ]

Contact: Chris Chipello christopher.chipello@mcgill.ca 514-398-4201 McGill University

As they develop, vertebrate embryos form vertebrae in a sequential, time-controlled way. Scientists have determined previously that this process of body segmentation is controlled by a kind of "clock," regulated by the oscillating activity of certain genes within embryonic cells. But questions remain about how precisely this timing system works.

A new international cross-disciplinary collaboration between physicists and molecular genetics researchers advances scientists' understanding of this crucial biological timing system. The study, co-authored by McGill University Prof. Paul Franois and Ohio State University Prof. Sharon L. Amacher and published in Developmental Cell, sheds light on the clock mechanism by providing the first real-time, visual evidence of how it operates at the level of individual cells.

While previous scientific studies have examined the oscillation phenomenon in the tissue of mouse embryos, the McGill and Ohio State researchers were able to observe and analyze it in single cells. To do so, they genetically modified zebrafish a freshwater fish whose body is nearly transparent during early development, making its anatomy easy to observe. The researchers used a fluorescent marker in the transgenic fish and developed software tools to monitor the concentration of a certain "cyclic" protein, whose production rises and falls with the oscillating expression of the molecular clock genes.

It is known that cells communicate with neighboring cells through a messaging system known as the Notch signaling pathway. In their experiments with the zebrafish, the researchers cut off this inter-cellular communication network enabling them to see how that would affect the oscillation pattern in individual cells and their neighbors.

These experiments revealed that cyclic protein concentrations in individual cells of the zebrafish continued to rise and fall, indicating that they continued to oscillate. With the inter-cellular signaling pathway blocked, however, the oscillations were no longer synchronized among neighboring cells. The cellular clocks were still ticking, in other words, but not in unison. This finding confirms that the Notch pathway serves to coordinate timing among cells a crucial role, since the cells must act in concert in order to form vertebrae.

By observing normal zebrafish embryos, the researchers were also able to show that cells desynchronize their oscillations while performing cellular division, then later resynchronize with their neighbors as they proceed collectively to form vertebrae.

"In humans, defects in Notch signaling are associated with congenital developmental disorders called spondylocostal dysostosis, that are typified by scoliosis and trunk dwarfism caused by malformed ribs and vertebrae," Amacher notes. "Studies such as ours may provide insight into potential therapies for human disease. It is likely that many cells in our bodies - stem cells, cancer cells - have similar molecular oscillators that regulate response to environmental signals. By unraveling such molecular clocks, we can understand how to modify them and thus change the number of oscillating cells that respond to differentiating signals, providing tremendous insight for studies in stem cell and cancer biology and tissue engineering."

"The formation of the vertebral column is very important, because everything follows from that" in the development of vertebrates, Franois adds. A physicist, he developed the computer tools used to analyze video footage of the zebrafish embryos. Francois's research focuses on the modeling of physical properties of gene networks and their evolution a field that has emerged at the nexus of biology and physics in recent years, following sequencing of the human genome and rapid growth in scientists' understanding of the processes inside cells.

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Can the addition of radiolabeled treatments improve outcomes in advanced metastatic disease?

Public release date: 13-Nov-2012 [ | E-mail | Share ]

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 x2156 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, November 12, 2012--Radiolabeled agents are powerful tools for targeting and killing cancer cells and may help improve outcomes and lengthen survival times of patients with advanced disease that has spread beyond the initial tumor site. Effective therapy for metastatic cancer requires a combination of treatments, and the benefits of adding radionuclide therapy are explored in three studies published in Journal of Clinical Investigation, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The articles are available free on the Journal of Clinical Investigation website.

"The preliminary therapeutic results reported in these case studies using radionuclide multimodality approaches are encouraging," says Co-Editor-in-Chief Donald J. Buchsbaum, PhD, Division of Radiation Biology, Department of Radiation Oncology, University of Alabama at Birmingham. "The outcomes described in these small, single center studies must be confirmed in larger trials before they can be translated into widespread oncology practice."

J. Harvey Turner, MD, FRACP, The University of Western Australia, Fremantle, coauthored two of the case studies and, in the Perspective article "Multimodality Radionuclide Therapy of Progressive Disseminated Lymphoma and Neuroendocrine Tumors as a Paradigm for Cancer Control," he states that the synergistic effects that can be achieved by combining chemotherapy and radionuclides "has the potential to enhance efficacy and minimize toxicity." Although advanced forms of lymphoma and neuroendocrine tumors are usually incurable, multimodal treatment approaches may be able to stop or slow tumor progression, achieve durable remission, prolong patient survival, and improve their quality of life.

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Paul Kruger, Julian Cooney, and J. Harvey Turner report that more patients survived longer and were free of disease when a radioimmunotherapeutic agent was added to their treatment regimen in the article "Iodine-131 Rituximab Radioimmunotherapy with BEAM Conditioning and Autologous Stem Cell Transplant Salvage Therapy for Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma."

Phillip Claringbold, Richard Price, and J. Harvey Turner added a lutetium-177 labeled peptide to the therapeutic regimen of a group of patients with advanced neuroendocrine cancer and described substantially improved tumor control rates with no significant side effects. They report their findings in "Phase I-II Study of Radiopeptide 177Lu-Octreotate in Combination with Capecitabine and Temozolomide in Advanced Low-Grade Neuroendocrine Tumors."

About the Journal

Journal of Clinical Investigation, published 10 times a year in print and online, is under the editorial leadership of Editors Donald J. Buchsbaum, PhD, Division of Radiation Biology, Department of Radiation Oncology, University of Alabama at Birmingham, and Robert K. Oldham, MD, Lower Keys Cancer Center, Key West, FL. Journal of Clinical Investigation is the only journal with a specific focus on cancer biotherapy, including monoclonal antibodies, cytokine therapy, cancer gene therapy, cell-based therapies, and other forms of immunotherapy. The Journal includes extensive reporting on advancements in radioimmunotherapy and the use of radiopharmaceuticals and radiolabeled peptides for the development of new cancer treatments. Topics include antibody drug conjugates, fusion toxins and immunotoxins, nanoparticle therapy, vascular therapy, and inhibitors of proliferation signaling pathways.

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Should hyperbaric oxygen therapy be used to treat combat-related mild traumatic brain injury?

Public release date: 13-Nov-2012 [ | E-mail | Share ]

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, November 13, 2012The average incidence of traumatic brain injury (TBI) among service members deployed in Middle East conflict zones has increased 117% in recent years, mainly due to proximity to explosive blasts. Therapeutic exposure to a high oxygen environment was hoped to minimize the concussion symptoms resulting from mild TBI, but hyperbaric oxygen (HBO2) treatment may not offer significant advantages, according to an article in Journal of Neurotrauma, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Journal of Neurotrauma website at http://www.liebertpub.com/neu.

A prospective trial conducted at the U.S. Air Force School of Aerospace Medicine evaluated the benefits of HBO2 therapy on post-concussion symptoms in 50 military servicepersons who had suffered at least one combat-related mild TBI. The study, "The Effect of Hyperbaric Oxygen on Symptoms Following Mild Traumatic Brain Injury," compared the results following 30 sessions of either HBO2 (2.4 atmospheres absolute pressure) or sham treatment over an 8-week period.

George Wolf, MD and Leonardo Profenna, MD, U.S. Air Force School of Aerospace Medicine (San Antonio, TX), David Cifu, MD and William Carne, PhD, Virginia Commonwealth University (Richmond), and Laura Baugh, MD, Uniformed Services University of the Health Sciences Department of Neurology (Bethesda, MD), present data demonstrating that both patient groups showed significant improvement in concussion assessment and cognitive testing scores over the course of the study.

"This is a particularly important communication that addresses a continued area of controversy, particularly as it relates to the treatment of our military personnel sustaining mild traumatic brain injury," says John T. Povlishock, PhD, Editor-in-Chief of Journal of Neurotrauma and Professor, VCU Neuroscience Center, Medical College of Virginia, Richmond. "While the authors stress that based upon their findings, larger multi-center, randomized, controlled, double-blinded clinical trials should be conducted, the compelling data in this communication does not support any therapeutic value for hyperbaric oxygen treatment, striking a cautionary note for those involved in the care and management of this patient population."

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About the Journal

Journal of Neurotrauma is an authoritative peer-reviewed journal published 24 times per year in print and online that focuses on the latest advances in the clinical and laboratory investigation of traumatic brain and spinal cord injury. Emphasis is on the basic pathobiology of injury to the nervous system, and papers and reviews evaluate preclinical and clinical trials targeted at improving the early management and long-term care and recovery of patients with traumatic brain injury. Journal of Neurotrauma is the Official Journal of the National Neurotrauma Society and the International Neurotrauma Society. Complete tables of content and a sample issue may be viewed on the Journal of Neurotrauma website at http://www.liebertpub.com/neu.

About the Publisher

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WT cloning research advances field

Amarillo, TX -- New research at WTAMU is putting the school at the forefront of genetic engineering.

Scientists at WT are celebrating the successful birth of a cloned calf - their second this year. And these two recent successes represent major strides toward improving stock lines, and ultimately, our food supply.

The word "cloning" tends to make many people uneasy, but in this sense, "cloning" is really just an expedited form of selective breeding.

"Alpha," a young bull, and "Gamma," a days-old heifer, were recently born using a process called somatic cell nuclear transfer. In simplest terms, that means putting a reprogrammed cell into a surrogate mother. The idea is that by systematically improving the gene pool, you can create better and stronger breeds, as WTAMU Associate Professor of Animal Science Dr. Ty Lawrence explains,

"We hope to create a new breed of cattle that currently does not exist. And this new breed of cattle will be a piece of the best of the best of the best from all existing breeds and their crosses."

By isolating the most desirable traits, researchers can create higher-yield cattle more resistant to drought and disease, as veterinarian Dr. Greg Veneklasen says,

"It's not just about meat; this is about genetic disease, this is about infectious disease. This is a model that we've created that we can use ... we can use this model for many different things."

And each new model is a step closer toward creating the ideal food animal.

Alpha and Gamma, for instance, are both Yield Grade One Prime beef, which represents about one in 15,000 cattle.

And advances like these are putting WTAMU on the map, as Dr. Don Topliff says,

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Research into Genetic Link of Autism Spectrum Disorder Earns Prestigious Edison Patent Award from the Research …

Research of James Millonig, PhD, Featured in Video at Award Ceremony on November 8

Newswise Piscataway, NJ Research that contributed to the development of a new genetic test for Autism Spectrum Disorder (ASD) has earned scientists at the University of Medicine and Dentistry of New Jersey (UMDNJ)-Robert Wood Johnson Medical School and Rutgers, The State University of New Jersey, the coveted Edison Patent Award from the Research & Development Council of New Jersey. The award recognizes a UMDNJ patent (U.S. Patent 7,629,123) for research that established an association between Engrailed Homeobox 2, (EN2), a gene involved in human development, and susceptibility for autism and related disorders. Diagnostic tools developed through this research have been used, in part, to test for the risk of autism in children who have siblings already diagnosed with the disorder.

As a New Jersey-based health and sciences institution and participating site in the CDCs autism study, we are very proud of this patent and its recognition by the Research & Development Council of New Jersey, said James Millonig, PhD, associate professor of neuroscience and cell biology and a member of the Center for Advanced Biotechnology and Medicine at Robert Wood Johnson Medical School.

In families where one child has been diagnosed with ASD, there is an increased risk that siblings also will be diagnosed with the disorder, providing evidence of a genetic component in the development of autism. This predisposition in siblings is the basis for research that established the link between EN2 and autism led by Dr. Millonig, in collaboration with Linda Brzustowicz, MD, professor and chair of genetics at Rutgers, The State University of New Jersey, and Neda Gharani, PhD, senior research scientist at the Coriell Institute.

The patented research recognized in the medical diagnostic category by the Research & Development Council of New Jersey, relates to compositions that can be used to help determine the predisposition, onset, or presence of ASD in children. Additional research by the team has shown that the ASD-associated genetic variant is functional and increases EN2 levels. Therapeutic methods for treating a child diagnosed with, or at-risk for, developing ASD, by adjusting the level or activity of EN2 also are included in the patent.

Diagnosis of ASD through professionally-developed observational techniques generally does not occur before age 3. It is the hope of the research team that the gene-based approach they have patented may lead to accurate diagnoses even sooner.

Earlier diagnosis means earlier treatment, which has enormous potential to improve social and communicative delays, thereby enhancing a childs ability to assimilate into the mainstream. said Dr. Millonig. Reducing the severity of symptoms related to Autism Spectrum Disorder, and possible the incidence of it, also may lead to lower costs for long-term treatment.

The Research & Development Council of New Jersey presented the award to Dr. Millonig and his team on Thursday, November 8. The presentation included a short video about the patent and Dr. Millonigs research, which can be found at: http://tinyurl.com/aaby5cs.

About UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL As one of the nations leading comprehensive medical schools, UMDNJ-Robert Wood Johnson Medical School is dedicated to the pursuit of excellence in education, research, health care delivery, and the promotion of community health. In cooperation with Robert Wood Johnson University Hospital, the medical schools principal affiliate, they comprise one of the nation's premier academic medical centers. In addition, Robert Wood Johnson Medical School has 34 other hospital affiliates and ambulatory care sites throughout the region.

As one of the eight schools of the University of Medicine and Dentistry of New Jersey with 2,800 full-time and volunteer faculty, Robert Wood Johnson Medical School encompasses 22 basic science and clinical departments, hosts centers and institutes including The Cancer Institute of New Jersey, the Child Health Institute of New Jersey, the Center for Advanced Biotechnology and Medicine, the Environmental and Occupational Health Sciences Institute, and the Stem Cell Institute of New Jersey. The medical school maintains educational programs at the undergraduate, graduate and postgraduate levels for more than 1,500 students on its campuses in New Brunswick, Piscataway, and Camden, and provides continuing education courses for health care professionals and community education programs. To learn more about UMDNJ-Robert Wood Johnson Medical School, log on to rwjms.umdnj.edu. Find us online at http://www.Facebook.com/RWJMS and http://www.twitter.com/UMDNJ_RWJMS.

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Penn state researchers study genetic mutations in Zebrafish

November 15, 2012 Courtesy of Matt Solovey

By Michael Martin Garrett

Researchers from the Penn State College of Medicine at Hershey Medical Center have recently completed a study that found that zebrafish can be used to test the effects of genetic mutations in humans.

[Zebrafish] genes are similar enough that if [someone] mutates the genes or knocks them down, what will happen is very similar to what will happen in humans, said lead researcher Dr. Keith Cheng.

In the future, the process and results of the study may be used to test the functions of genetic mutations, Cheng said.

This kind of research, being able to functionally test human mutations in a living model organism, can lend much support to the developing field of personalized medicine, Steven Wentzel , a Penn State graduate student and researcher on the study, wrote in an email.

Wentzel wrote that many scientific studies have identified numerous genes that are linked to various diseases, but by being able to test individual genetic mutations we can gain insight into what roles they may play in human disease, allowing us to prioritize treatment targets.

Cheng said there are many different combinations of mutations, and these mutations can be very small, with the difference of only a single amino acid between two versions of the same gene.

Everybody knows that were going to be carrying our DNA sequence around in our iPhones soon, but were not going to know what all of our mutations mean, Cheng said.

According to the abstract of the study, the approach may be extended to other model systems and could contribute to the understanding of the relationships between DNA sequence variation, human biology and disease.

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Genetic mutation linked to Alzheimer’s disease

Washington, November 15 (ANI): A mutation in an immune system gene may contribute to a person's risk of developing Alzheimer's disease, Canadian researchers have found.

Using data from 25,000 people, researchers from the Faculty of Medicine and University College London's Institute of Neurology discovered that a rare genetic mutation in the TREM2 gene - which helps trigger immune system responses - is also associated with increased risk of Alzheimer's.

The discovery supports an emerging theory about the role of the immune system in the disease.

"This discovery provides an increasingly firm link between brain inflammation and increased risk for Alzheimer's," says Dr. Peter St George-Hyslop, director of University of Toronto's Tanz Centre for Research in Neurodegenerative Diseases.

"This is an important step towards unraveling the hidden causes of this disease, so that we can develop treatments and interventions to end one of the 21st century's most significant health challenges."

The team began by sequencing the genes of 1,092 people with Alzheimer's and a control group of 1,107 healthy people. The results showed several mutations in the TREM2 gene occurred more frequently in people who had the disease than in those without the disease. One mutation - known as R47H - had a particularly strong association with the disease.

The mutation makes a patient three times more likely to develop the disease, although it affects just 0.3 per cent of the population.

"While the genetic mutation we found is extremely rare, its effect on the immune system is a strong indicator that this system may be a key player in the disease," says Dr. Rita Geurreiro from UCL, the study's lead author.

The study has been published in the New England Journal of Medicine. (ANI)

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Sanofi-Institut Pasteur 2012 Awards: Interview of Professor Peter Palese – Video


Sanofi-Institut Pasteur 2012 Awards: Interview of Professor Peter Palese
Peter Palese is Professor and Chairman of the Department of Microbiology of the Mount Sinai School of Medicine in New York City. He is honored for his fundamental work on the genetics of influenza viruses.From:sanofiaventisTVenViews:5 1ratingsTime:01:41More inScience Technology

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True Strength Now – The Real Deal Strength Building


True Strength Now - The Real Deal Strength Building Strength Gain Routine By Todd Walsh (truestrengthtodd)
xxsurl.com True Strength Now - The Real Deal Strength Building Strength Gain Routine By Todd Walsh (truestrengthtodd) True Strength Now - The Real Deal Strength Building Strength Gain Routine By Todd Walsh (truestrengthtodd) This is me deadlifting 405 lbs 3 times. Looks pretty easy rightb Give it a try. Home | Contact TRUE STRENGTH NOW! A strength training program that will make you STRONGER THAN YOU HAVE EVER BEEN. A 10 week program that can change your life. By Todd Walsh A regular 41 year old guy who takes getting strong very seriously The truth is genetics determine how strong you can get. The good news is that most people (99%) have never even come close to their true strength potential. The routine included in my e-Book will help you unlock the strength within you. I know, you #39;ve been told through the media and magazines that there is a trick to being strong, or a supplement that can make you strong. The plain truth is that to be strong you need to be dedicated and you need a good routine. There just isn #39;t an easy way or short cut. There are however easier ways and good routines that can make all the difference in helping you achieve your strength goals. What I can do is show you how to get as strong as you can possibly be by introducing you to a simply fantastic strength gain routine. So, how strong can you getb The only way to answer you is to tell you how strong I am. Well... at my last body composition test I was 20% body fat and was slightly dehydrated ...From:lessanders396Views:0 0ratingsTime:01:57More inPeople Blogs

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Humans Getting Dumber As Species – Video


Humans Getting Dumber As Species
A scientist claims humans are potentially getting dumber as a species. Are humans getting dumber as a species? Stanford University professor Gerald Crabtree #39;s research into human kind #39;s intelligence suggests that due to the low level of competition for basic necessities in the modern world, the best and brightest aren #39;t the only ones naturally selected for survival and procreation anymore. Civilization and modern medicine allow for even the dumbest and most physically unfit to survive and pass their genes on to the next generation. In the distant past, survival wasn #39;t so easy. The Darwinian concept of evolution dictates that only the people who could navigate the complexities of life on earth would be able to live on and provide for their offspring. Crabtree says: "New developments in genetics, anthropology, and neurobiology... make a clear prediction that our intellectual and emotional abilities are genetically surprisingly fragile." When comparing genomes of parents and their children, it turns out that there are somewhere between 25 and 65 DNA mutations between each generation. Other scientists oppose Crabtree #39;s ideas saying that there is no real way to test his theory. What do you think? Are humans getting dumber due to the conveniences of modern life?From:geobeatsViews:4 7ratingsTime:01:14More inEducation

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EPXBody finally helps to lose weight even without diet – Video


EPXBody finally helps to lose weight even without diet
Building a brand that can change the future of literally millions of people is not something that we take lightly. EPXbody was founded by Dan Putnam with the vision of teaching people that your past does not have to equal your future. You have control over our health and wealth and now with EPXbody you can have the vehicle to reach your goals. EPX is short for Epigenetics; science has shown that with proper nutrition, diet and exercise, you can improve your genetics and the genetics of generations to follow. Not only do we feel that our products can change your health but we also know there is an urgent need for people to improve their financial health as well. Our vision as a company is to impact our members #39; health and wealth positively by providing them with the best nutritional products, diet and exercise information, as well as all the tools and training needed to build a successful home-based business. This will allow our members to improve their own lives as well as the people they know love and care about. win 1000 bucks monthly just for watching this short video: http://www.getepx.com/successmaker It will ask for your name, e-mail and tel. no to direct you to the videoFrom:Paula GerendásViews:0 0ratingsTime:02:49More inPeople Blogs

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BSA ND3 – Video


BSA ND3
Get a great deal here redirect.viglink.com?key=1f0527e04637dcdb26bf99b11836bfbf out=http%3A%2F%2Fwww%2Eamazon%2Ecom%2Fdp%2FB005KU1NQU Product Description BSA ND3 The ND-3® x50 Laser Designator is the latest precision optical lighting instrument from Laser Genetics using advanced green laser technology. It is equipped with a 50mm lens and the strongest laser that we have ever manufactured for this application. The patented Rotary Optical Collimator allows full easy adjustment and control of the beam diameter and intensity to focus light where you need it most. Rotating the collimator provides a range of illumination, enough to light a trail or pursue a target in close quarters at night or paint a target up to 500 yards*! Specifications - Precision machined from high tech aluminum - Black matte anodized finish - Fully O-Ring sealed for dust and water - Fully Multi-Coated optical lens system - Nitrogen charged for anti-fog - 1" Tube adapts to multiple mounting systems - Dimensions: 9.45"LX 2.35" Dia. X 1.0" Dia. Tube - Weight: 13.5 OZ. - Power Supply: 2 CR123A Batteries (Incl.) - Output Power: 40mW - Rotary optical beam collimator - allows quick adjustment of beam diameter and intensity - 532nm (Green) Laser light frequency - easiest light for the human eye to see (See Chart) - Amplified coherent light - most efficient light for long distance illumination - RANGE: UP TO 5.0 MILES (Range might vary depending on weather conditions) - 1 Year warranty - FDA Safety Class: 2M ...From:lurlene logueViews:0 0ratingsTime:00:52More inScience Technology

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Dr. Rick Kaht Teacher of the Year for Cobb County picks up his New Honda Pilot – Video


Dr. Rick Kaht Teacher of the Year for Cobb County picks up his New Honda Pilot
Dickerson Middle School #39;s Dr. Richard Kaht aims to get his students excited about exploring science, using humor and hands-on reinforcement. Dr. Kaht said, "If students do not enjoy my Life Science class, it will be that much harder for them to learn the material and take ownership in the concepts." For example, after discussing Gregor Mendel #39;s study of genetics by growing peas, students grew their own peas in the classroom. "I try to not only teach a subject, but also present skills of learning and the idea that they can be successful and accomplish great things." During the 2011-2012 school year, Dr. Kaht started Dickerson #39;s FTC Robotics Club for students as a fun, extracurricular extension of the science concepts covered during class time. In its first year, the team competed against teams of high school students and earned two top ten finishes. Since joining Dickerson in 1999, Dr. Kaht has participated in the DMS Leadership Team, helped implement the Olweus Bullying Prevention program and collaborated with other science teachers to improve instruction throughout Cobb CountyFrom:EdVoylesHondaViews:0 0ratingsTime:00:51More inEducation

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Hcg Diet Guide – A Revolution In Weight Loss – Video


Hcg Diet Guide - A Revolution In Weight Loss
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How To Grow Taller? – Video


How To Grow Taller?
http://www.growth-flex.com - How to grow taller? Most short people often tend to lack confidence and self-esteem more than those of average height because they feel like they are "below" the average height in sports, career or even finding a love partner. "Genetics and nutrition have the biggest impact on your height. How much of human height is genetic and how much is due to nutrition? About 60 to 80 percent of our difference in height between individuals is determined by genetic factors, whereas 20 to 40 percent can be attributed to environmental effects, mainly nutrition". Learn how to grow taller without the needs for expensive surgeries. For more information please visitFrom:TallerGrowNowViews:0 0ratingsTime:00:34More inHowto Style

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Gene Jones – Video


Gene Jones
Gene Jones: Mutation Hunter A short film made as part of a two day workshop on science communication. This is what happens when four scientists are told to explain their research, given a camera and eight hours to make a film... Thanks to Genetics Otago, The Centre for Science Communication and our tutor Steve Ting.From:TheRocketGrrrlViews:13 0ratingsTime:02:33More inMusic

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Gene Jones - Video

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How to Effectively Structure and Use Board of Directors/Advisers – Video


How to Effectively Structure and Use Board of Directors/Advisers
In this workshop, we #39;ll discuss how to build a Board and get the most out of it, including strategy and considerations for selecting, utilizing and compensating Directors and Advisors. About the speaker: Chad Stiening of Mentor Management is a University of Illinois graduate (Class of #39;99, BS Biology, BS Finance) who is currently running a medical diagnostic device company, Kypha, Inc., located at the BioGenerator Accelerator Labs in St. Louis. He has a PhD in Molecular Genetics from the University of Arizona, and previously worked as a business development executive at the University of Louisville-affiliated Research Park and Innovation Center, NUCLEUS. He is passionate about University of Illinois and helping entrepreneurs with the practical work needed to advance life science start-ups and technology commercialization, from market analysis and regulatory planning to early-stage financing and growth strategies.From:researchparkuiucViews:0 0ratingsTime:01:03:06More inScience Technology

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Savage Genetics -Silent Hill(Tyler Terror REMIX) – Video


Savage Genetics -Silent Hill(Tyler Terror REMIX)
Facebook: http://www.facebook.com Welcome to Silent Hill! Original Song: Savage Genetics - Silent Hill Silent Hill belongs to Konami, I do not own the game or movies in any way, nor the original song, just the remix. If you enjoyed, please like and subscribe. 2012, T0XiiCKANDY Studios, all rights reserved.From:RumagrizzViews:1 0ratingsTime:03:48More inMusic

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Alzheimer’s Gene Trem2 Variant Discovered by BYU, International Research Team – Video


Alzheimer #39;s Gene Trem2 Variant Discovered by BYU, International Research Team
BYU plays major role in discovery of new Alzheimer #39;s risk gene;Global study suggests immune response plays key role in Alzheimer #39;s development Scientists at BYU and several other leading Alzheimer #39;s research institutions have discovered a rare genetic mutation that increases the risk of Alzheimer #39;s disease. The international team of researchers report in this week #39;s issue of the New England Journal of Medicine that a rare variant of TREM2, a gene associated with the immune system, is linked to a higher risk of Alzheimer #39;s. The study, which used genetic data from more than 25000 people, suggests that problems with the immune system could be a key player in the development of Alzheimer #39;s. "Discovering a new gene for Alzheimer #39;s disease is major step in learning about the genes, proteins and biological pathways that actually cause disease," said BYU geneticist John "Keoni" Kauwe, a co-author on the study. "And that #39;s what we need to know to come up with ways to prevent or cure Alzheimer #39;s." Treatments for the disease have been unsuccessful because by the time a person is diagnosed, the disease has already been crippling the brain for years. Scientists like Kauwe are doing the science behind future diagnostic tests that will hopefully predict Alzheimer #39;s five, 10 or 15 years before onset. Kauwe #39;s BYU team provided the initial validation of the discovery and contributed more than 200 complete human genomes to the study. Ph.D. student Perry Ridge did the analysis of the whole ...From:BYUNewsViews:6 0ratingsTime:01:36More inScience Technology

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Alzheimer's Gene Trem2 Variant Discovered by BYU, International Research Team - Video

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Cool Cell – Video


Cool Cell
Pure York Premium Blend GeneticsFrom:lairdhampsViews:19 0ratingsTime:00:39More inPets Animals

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Cool Cell - Video

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Discovery Presents Dinosaurs Return to Life . – Video


Discovery Presents Dinosaurs Return to Life .
Discovery Channel presents the premiere of Dinosaurs: Return to Life, a startling one-hour special that virtually turns back the clock to the Jurassic period and recreates the dinosaurs that ruled the planet 200 million years ago. Through rapid advances in genetics, scientists are discovering the genetic traits of dinosaurs in the DNA of birds. They are showing that it is possible to bring back teeth, long tails and hands in place of wings. In Dinosaurs: Return to Life, learn why the dream of recreating the dinosaur genome is coming closer to reality.From:TheFlorinmartinezViews:4 0ratingsTime:43:32More inScience Technology

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Discovery Presents Dinosaurs Return to Life . - Video

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Learn How To Quickly and Permanently Eradicate Your Autoimmune Disease – Video


Learn How To Quickly and Permanently Eradicate Your Autoimmune Disease
Learn How To Quickly and Permanently Eradicate Your Autoimmune Disease. tinyurl.com For several years, genetics has been the absolutely no. 1 explanation traditional medicinal practises is offering for autoimmunity development. Nonetheless it will not explain why one child from a mother develops an autoimmune disease once the other five never obtain it. No, all disease have a very distinctive span of development and now, for the first time ever, one can learn what exactly is it about yourself that made you afflicted with a change inside immune response. It is important to realize that autoimmunity never goes alone. It causes all sort of disturbances withinside the normal functioning with the body as it initiates a vicious cycle of hormonal changes, enzyme disruptions and organ malfunctions. The Autoimmunity Bible Norton Protocol, This breakthrough product is the only system around that provides you the capacity to: [ 1 ] For the first time ever, pinpoint the underlying reasons for your condition and know very well what is going on [ 2 ] Heal your disease permanently [ 3 ] Eliminate the culprits of the pain completely inside two weeks [ 4 ] Heal your disease holistically. When you have tried different diets, potions and drugs the traditional medicine recommends, you realize chances are which they simply fail or that they #39;re a "fast solution" before your pain comes home having a vengeance. [ 5 ] Heal your disease minus the horrible side effects of conventional drugs. An ...From:Mr4anewwayViews:0 0ratingsTime:01:38More inHowto Style

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Billy Ray Meet Illana Rudnick – Video


Billy Ray Meet Illana Rudnick
My cousin Illana Runick is Billy Ray Cyrus #39;s biggest fan. She has a genetic disorder called cri du chat. I (Katelyn Cordero) have been trying for the last few years to get her to meet him but have come up unsuccessful. I am looking for anyone who can help me to grant my cousin #39;s wish! For more information on Cri Du Chat you can take a look at these websites: http://www.fivepminus.org learn.genetics.utah.edu http://www.genome.gov en.wikipedia.orgFrom:95kcorderoViews:0 0ratingsTime:04:04More inEntertainment

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Billy Ray Meet Illana Rudnick - Video

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NEET ACADEMY – Genetics Paediatrics – Video


NEET ACADEMY - Genetics Paediatrics
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NEET ACADEMY - Genetics Paediatrics - Video

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Centenary Institute Lawrence Creative Prize 2012 – Video


Centenary Institute Lawrence Creative Prize 2012
The winner of the Centenary Institute Lawrence Creative Prize is Dr Jian Yang, from the Diamantina Institute of the University of Queensland. He has solved one of the great puzzles of human genetics mdash;why the genes typically implicated in inherited diseases like schizophrenia, obesity and diabetes only account for a small amount of their heritability. Read more about his great achievement here: bit.lyFrom:CentenaryInstituteViews:5 0ratingsTime:02:15More inScience Technology

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Centenary Institute Lawrence Creative Prize 2012 - Video

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