Gun of God by David Cudlip
http://www.amazon.com Thomas Courmaine, a geneticist and a card-carrying idealist, is banished to Africa; this, for his own well-being. There, he is intrigued by age-old bush medicine, and his stars are about to shine when he stumbles upon the long-sought solution to the riddle of gene therapy. Watershed stuff, to say the least, paving the way for eradicating thousands of diseases...on the cheap. With gene therapy freely available, people will rarely get ill. Thus, who needs drugs? Or doctors and hospitals? With trillions of dollars at stake, and taking no chances, the pharma-industry offers Courmaine an alliance. If only he #39;ll play ball. When he refuses, they take aim, with full intentions of thwarting his quest of bringing free health care to the vast numbers needing it. One battle begets the next. Courmaine #39;s discovery makes it relatively simple to quickly edit and even re-edit one #39;s DNA. The gun of the future soon fires. A new era explodes, and the race is on to see who can become faster, brighter, more beautiful...and thus what began as a magical panacea now looms as a full-fledged curse. Are we to remain as humans, letting Nature do what Nature does in her own way and in her own time; or do we artificially keep transforming ourselves into what we were never meant to be? Where and how does this whirligig end? Can the Genie ever be returned to its bottle? Courmaine must cope with irony at its very apex: to save humanity #39;s essence can he somehow undo the great things he has ...From:WillMoffettMusicViews:226 1ratingsTime:00:35More inEntertainment

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Kernicterus
ll4.me Kernicterus Dedication page.- Preface.- Acknowledgement.- Key words.-Chapter 1 Prologue: Hyperbilirubinemia, kernicterus, and world health concerns.-Chapter 2 History of bilirubin.-Chapter 3 Biochemistry and physiology of bilirubin.- Chapter 4 Prematurity.- Chapter 5 Erythroblastosis fetalis.- Chapter 6 Gunn rats.- Chapter 7 Crigler-Najjar Syndrome.- Chapter 8 Neuropathology of kernicterus.- Chapter 9 Bilirubin and energy metabolism.- Chapter 10 Bilirubin and other biochemical changes.- Chapter 11 Jaundice and breast milk.- Chapter 12 Jaundice and malaria.- Chapter 13 Jaundice and congenital pyloric stenosis.- Chapter 14 Phototherapy for hyperbilirubinemia.- Chapter 15 Non phototherapy treatment.- Chapter 16 Hyperbilirubinemia revisited.- Chapter 17 Auditory brainstem response.- Chapter 18 Progressive familial intrahepatic cholestasis.- Chapter 19 Kernicterus in older children and adults.- Chapter 20 Cerebral palsy and counseling.- Chapter 21 Neurological sequelae from jaundice.- Chapter 22 Neurobehavioral teratology.- Chapter 23 Gene therapy for hyperbilirubinemia.- Chapter 24 Epilog: Kernicterus: comments and future directions.- Appendix.- References.- Index EAN/ISBN : 9781441965554 Publisher(s): Springer, Berlin, Springer Science Business Media Discussed keywords: Neurowissenschaft Format: ePub/PDF Author(s): McCandless, David W. Dedication page.- Preface.- Acknowledgement.- Key words.-Chapter 1 Prologue: Hyperbilirubinemia, kernicterus, and world health ...From:louisegibbons9865Views:0 0ratingsTime:00:11More inPeople Blogs

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Post-genomic Cardiology
ll4.me Post-genomic Cardiology Recent advances in molecular and cellular biology have markedly changed our understanding of the heart, and this is having tremendous ramifications for the clinician. This unique reference offers a comprehensive and critical evaluation of this contribution in the field of cardiovascular molecular medicine providing the reader with a sense of new directions in which molecular medicine might be applied. It begins with a detailed primer that makes readily accessible recent molecular, genetic and cellular techniques. Rounding out the coverage of this exciting field are critical and comprenhesive discussions on the use of molecular, genetic and cellular techniques used to identify the etiology and pathophysiology of specific cardiac diseases.* Discusses diagnostic and therapeutic options available not only in the adult and aging individuals but also in infants/children* Numerous illustrations and flow-charts* Explans cutting-edge molecular techniques, including analysis of mitochondria, their role in cardiac dysfunction and updated analysis of Cardioprotection and Metabolic Syndrome* Presentation of recent translational studies for the treatment of cardiovascular diseases is included (eg, gene therapy, pharmacological treatments and stem cell transplantation) Publisher: Academic Press Illustration: Y Language: ENG Title: Post-Genomic Cardiology Pages: 00000 (Encrypted PDF) On Sale: 2007-02-26 SKU-13/ISBN: 9780123736987 Category: Medical ...From:julianlewis9854Views:0 0ratingsTime:00:14More inPeople Blogs

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An Introduction To Genetic Engineering - Desmond ST Nicholl
ll4.me An Introduction To Genetic Engineering - Desmond ST Nicholl Des Nicholl presents here a new, fully revised, and expanded edition of his popular undergraduate-level textbook. Many of the features of the original edition have been retained; the book still offers a concise technical introduction to the subject of genetic engineering. However, the book is now divided into three main sections: the first introduces students to basic molecular biology, the second section explains the methods used to manipulate genes, and the third deals with modern applications of genetic engineering. A whole chapter is now devoted to the polymerase chain reaction. Applications covered in the book include genomics, protein engineering, gene therapy, cloning, and transgenic animals and plants. A final chapter discusses the ethical questions surrounding genetic engineering in general. An Introduction to Genetic Engineering is essential reading for undergraduate students of biotechnology, genetics, molecular biology and biochemistry.Author: Nicholl,Desmond ST Publisher: Cambridge University Press Illustration: N Language: ENG Title: An Introduction to Genetic Engineering Pages: 00304 (Encrypted PDF) On Sale: 2002-02-07 SKU-13/ISBN: 9780521004718 Category: Science : Life Sciences - Genetics Genomics Des Nicholl presents here a new, fully revised, and expanded edition of his popular undergraduate-level textbook. Many of the features of the original edition have been retained; the book still ...From:jenniferhale9854Views:0 0ratingsTime:00:12More inPeople Blogs

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BANGALORE, November 9, 2012 /PRNewswire/ --

DNA Gene Therapy for Degenerative Diseases

In todays reality, terms like genetic engineering and gene therapy have become facts which prophets of science had only dreamt about few years ago. Pain, disability and disease have long plagued mankind, medicine has long sought its answers, research and development are yet uncovering labyrinths of technology to reach to a panacea.

Dr.Agarwal Hospitals nestled in bubbling Bangalore has brought out a customized version of GENE THERAPY where the patients own peripheral capillary blood (one drop) is taken as the raw stock admixed with Mana (DNA activator) it brings back healthy or fetal DNA of the same patient. This is then used as injections to the same patient within seconds of the mixture. A course of ten injections is given over a span of one week to ten days bringing about a healthy change in the patients course of disease.

Over 20 years of research conducted by Dr.Agarwal Hospitals on genetic engineering, where last 8 years have been spent on treating over 12000 patients through variety of illness in different stages of disease has brought new hope to mankind.

Mana (DNA activator) a propriety formula is taken in a syringe and customized with a drop of the patients blood. This forms the patients healthy DNA in vitro and is given back to the patient as sub cutaneous injections over a period of ten days every month for severe conditions.

Mana is a DNA activator - proven to recreate patients own healthy DNA

When Mana & Plasma are mixed within the first second healthy DNA strands start amplifying (proven through research and validation)

Its the patients own DNA being given back : No Side Effects

Dr.Sunita Rana Agarwal, Chief Scientist, Dr Agarwal Hospitals & Gene Research Foundation, carried out the research in this field on patients who were HIV positive. The CD4 ratio counts varied from 186 to 358 from 2004. In 90% of the patients CD4 ratio has increased to above 500 cells per micro liter.

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New Ray of Hope for HIV Patients

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Patricia Quick L-1/L-5 Spinal Cord Injury at Beyond The Chair
Our main focus at Beyond The Chair Neuro Recovery Gym is to stimulate the nerves and muscles below the level of injury to enhance function. We accomplish this through various exercise techniques and adaptive modalities. http://www.beyondthechair.org http://www.facebook.com/beyondthechair2011From:beyondthechairtexasViews:0 0ratingsTime:03:20More inNonprofits Activism

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Scott Driving System - Cooper
The Scott Driving System has been developed over the last 40 years and is a complete system which permits the physically challenged to safely perform all driving tasks without assistance, including entering and leaving the vehicle. The system provides for safe extended mobility for the driver who must remain in his or her wheelchair while driving. The system has been successful in a variety of disabilities. Patients with post polio, multiple sclerosis, muscular dystrophy, spinal atrophy and spinal cord injury up to C4/C5 are successfully driving on a daily basis.From:coachbob5Views:1 0ratingsTime:03:12More inAutos Vehicles

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Craig Hospital Pool Therapy
Dx- C 5/6 Spinal cord injury Transverse myelitis Working with my physical therapist at Craig hospital in the pool , DX Transverse myelitis , Incomplete Quadriplegic C5/6 Spinal cord injury Amazing pool therapy was so wonderful.. **check back will be uploading whole therapy in sequence soon**From:myQuadTherapyViews:2 0ratingsTime:00:32More inPeople Blogs

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Physical Therapy Gait Harness 2
My Physical Therapy with using the harness system and parallel bars, Working with my physical therapist, DX Transverse myelitis , Incomplete Quadriplegic C5/6 Spinal cord injuryFrom:myQuadTherapyViews:3 0ratingsTime:02:31More inPeople Blogs

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Standing with Physical Therapist
My Physical Therapy, Working with my physical therapist, DX Transverse myelitis , Incomplete Quadriplegic C5/6 Spinal cord injury, Standing at homeFrom:myQuadTherapyViews:2 0ratingsTime:01:10More inPeople Blogs

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stem cell banking | Cord Blood
http://www.cordbloodrecommendation.com ""There are several advantages to cord blood banking. Advantages Of Cord Blood Banking1. 2. There are many diseases that can be treated with stem cells, so if your child ever needs stem cells later in his/her life, you will not have to look for a new donor. Placental and cord blood banking may become even more valuable in the future with exciting research under way to find new medical uses in areas such as: diabetes, heart disease, liver disease, muscular dystrophy, Alzheimer #39;s disease, Parkinson #39;s disease, stroke, and even spinal cord injury. However, in the event that you actually need the cord blood, I am sure there is no price too high for a parent to be willing to pay. Sometimes people cannot use their own because it still may carry a genetic disorder. Thomas, who will not have access to a close relative #39;s stem cells. It is always wise to preserve this waste blood of the baby which is otherwise thrown away. In this case, it will be better to bank the cord blood for possible future need. Usually, cord blood stem cell banking comes with a payment package that sum up fees for enrollment information, collection kits, courier charges, banks laboratory, sample typing, processing, storing and maintenance of the cord blood units. In the future, researchers might be able to examine cord blood from babies with lung diseases such as cystic fibrosis and develop better treatments. Nowadays, there is a bank which provides you a service for storing ...From:Aldana LuisViews:0 0ratingsTime:01:18More inScience Technology

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umbilical cord | Cord Blood To Cure Thalassemia And Many More Diseases
http://www.cordbloodrecommendation.com In 2006, Shelia Gannon was close to the end of a losing battle against acute lymphoblastic leukemia (ALL), a form of cancer that causes abnormal blood formation and a shortage of red and normal white blood cells and platelets. . Now in a few words, stem cells are simply the beginning of all potential: a stem cell can be induced to form organs of a specific cell type, such as liver or kidneys, with the help of chemical and physical cues. Even if for some reason your donation isn #39;t eligible for transplant purposes, it can still be used for research. Placental and cord blood banking may become even more valuable in the future with exciting research under way to find new medical uses in areas such as: diabetes, heart disease, liver disease, muscular dystrophy, Alzheimer #39;s disease, Parkinson #39;s disease, stroke, and even spinal cord injury. Myth 2 : if your family doesn #39;t have a record of cancer, your baby or sibling won #39;t ever require stem cells. This is true especially in children. Thomas, who will not have access to a close relative #39;s stem cells. It is always wise to preserve this waste blood of the baby which is otherwise thrown away. Cord blood storage might become a new trend very soon. Usually, cord blood stem cell banking comes with a payment package that sum up fees for enrollment information, collection kits, courier charges, banks laboratory, sample typing, processing, storing and maintenance of the cord blood units. Around 40 to 150ml ...From:HotelesEnBuenosAiresViews:0 0ratingsTime:01:18More inScience Technology

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Physical Therapy gait and harness 3
My Physical Therapy with using the harness system and parallel bars, Working with my physical therapist, DX Transverse myelitis , Incomplete Quadriplegic C5/6 Spinal cord injuryFrom:myQuadTherapyViews:1 0ratingsTime:02:32More inPeople Blogs

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Yoga and spinal injury
I interview a student here briefly on how yoga has helped him feel more comfortable in his body after a spinal cord injury some 30 years ago. He started off in my aqua kriya yoga class and amazingly after a few months he now attends a land yoga class. Again, here he has made incredible progress starting with yoga on a chair, and then moving onto a yoga mat for some of the class. http://Www.aquakriyayoga.com for aqua training events http://Www.camellanair.comFrom:camyoga1Views:0 0ratingsTime:03:31More inSports

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Zynex Medical, Inc.
http://www.zynex.com Zynex (founded in 1996) engineers, manufactures, markets and sells its own design of medical devices in three subsidiaries. Zynex Medical is a provider of electrotherapy products for home use, Zynex Monitoring Solutions develops products for cardiac monitoring for use in hospitals and Zynex NeuroDiagnostics develops devices for EMG and EEG diagnostic purposes in the neurology clinic markets. Zynex Medical #39;s product line is fully developed, FDA-cleared, commercially sold, and has been developed to uphold the Company #39;s mission of improving the quality of life for patients suffering from impaired mobility due to stroke, spinal cord injury, or debilitating and chronic pain.From:zynexvideoViews:6 2ratingsTime:01:08More inScience Technology

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Keynote Speaker: Daniel Kraft bull; Presented by SPEAK Inc.
Stanford and Harvard Trained Physician-Scientist, Inventor, Entrepreneur and Innovator Dr. Daniel Kraft has over 20 years of experience in clinical practice, biomedical research and healthcare innovation. Daniel chairs the Medicine track for Singularity University and is Executive Director for FutureMed, a program which explores convergent, exponentially developing technologies and their potential in biomedicine and healthcare. Following undergraduate degrees at Brown and medical school at Stanford, Dr. Kraft was board certified in the Harvard combined Internal Medicine and Pediatrics residency program at the Massachusetts General Hospital and Boston Children`s Hospital. He went on to complete Stanford fellowships in hematology/oncology bone marrow transplantation, and extensive research in stem cell biology and regenerative medicine. He has multiple scientific publications (including in Nature and Science), medical device, immunology and stem cell related patents through faculty positions with Stanford University School of Medicine and as clinical faculty for the pediatric bone marrow transplantation service at UCSF. Dr. Kraft recently founded IntelliMedicine, focused on enabling connected, data driven, and integrated personalized medicine. He is also the inventor of the MarrowMiner, an FDA approved device for the minimally invasive harvest of bone marrow, and founded RegenMed Systems, a company developing technologies to enable adult stem cell based regenerative ...From:speakincViews:0 0ratingsTime:14:53More inPeople Blogs

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Keynote Speaker: Daniel Kraft • Presented by SPEAK Inc. - Video

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Integrating History And Philosophy Of Science
ll4.me Integrating History And Philosophy Of Science From the contents: Introduction by Seymour Mauskopf and Tad Schmaltz Part I: General Reflections Thomas Kuhn and Interdisciplinary Conversation: Why Historians and Philosophers of Science Stopped Talking to One Another , Jan Golinski The History and Philosophy of Science History, David M. Miller What in Truth Divides Historians and Philosophers of Science?, Kenneth Caneva History and Philosophy of Science: Recollections and Reflections, Ronald Giere Philosophy of Science and Its Historical Reconstructions , Peter Dear The Underdetermination Debate: How Lack of History Leads to Bad Philosophy, Wolfgang Pietsch Part II: Case Studies Beyond Case Studies: History as Philosophy, Hasok Chang Hidden Entities and Experimental Practice: Renewing the Dialogue between History and Philosophy of Science, Theodore Arabatzis Studying Methodological Thought: S. Weir Mitchell s Research on the Venom of Poisonous Snake, Jutta Schickore Quantum Gravity: History, Historiography and Philosophy, Dean Rickles Social Epistemology of Stem Cell Research: History, Philosophy and Experiment, Melinda Fagan History and Philosophy of Science at Work: Making Regenerative Medicine Better EAN/ISBN : 9789400717459 Publisher(s): Springer, Berlin, Springer Netherlands Discussed keywords: Geschichtsschreibung, Interdisziplinaritt, Wissenschaftsphilosophie Format: ePub/PDF Author(s): Mauskopf, Seymour - Schmaltz, Tad From the contents: Introduction by ...From:susanbranch9865Views:0 0ratingsTime:00:16More inPeople Blogs

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CombiCult Workflow
A overview on how Plasticell (www.plasticell.co.uk) uses combinatorial cell culture (CombiCult) to discover optimised stem cell differentiation protocols in record time, at a fraction of the cost of the status quo while reducing project return risk. CombiCult is used by our customers in a range of applications in regenerative medicine, cell therapy and research and development.From:PlasticellLimitedViews:0 0ratingsTime:06:40More inScience Technology

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CombiCult® Workflow - Video

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Vetrix
Overview of Vetrix, a veterinary regenerative medicine company.From:ReThinkHealingViews:1 0ratingsTime:01:40More inScience Technology

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AFIRM Wake Forest-Pittsburgh Consortium Research
The AFIRM #39;s success to date can be ascribed, at least in part, to the program #39;s emphasis on establishing partnerships and collaborations. Funding for the AFIRM is a six-way partnership among the US Army, Navy, and Air Force; the Veterans Health Administration; the Defense Health Program; and the National Institutes of Health. Research under the AFIRM is conducted through two independent research consortia working with the US Army Institute of Surgical Research (USAISR). One research consortium is led by Rutgers, the State University of New Jersey, and the Cleveland Clinic (RCCC [Rutgers-Cleveland Clinic Consortium]) while the other is led by Wake Forest University Baptist Medical Center and the McGowan Institute for Regenerative Medicine in Pittsburgh (WFPC [Wake Forest-Pittsburgh Consortium]). This video discusses some of the research taking place at the WFPC.From:USAMMDAViews:0 0ratingsTime:05:55More inEducation

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stem cell banking | Knowing More About Cord Blood Banking
http://www.cordbloodrecommendation.com The umbilical cord blood is rich in stem cells as the baby #39;s organs, tissues and body is developed by it. Diseases that are genetically based would most likely be an allogenic transplant. Human umbilical cord blood cells are very rich in stem cells and progenitor cells which make them the perfect place to take cells from and then store them in a cord blood bank or a stem cells bank. There is also another option given by non-profit cord blood banks, of free programs through which one can store umbilical cord blood stem cell samples. A man can change his god-gifted features wishfully with the help of science. Given the progress that stem cell research and regenerative medicine have attained at present, and the promise that they show for the future, stem cell transplants may one day provide a cure for type 1 diabetes, heart disease, and brain injury, among other potentially life threatening and debilitating illnesses and conditions with inadequate treatment options today. One study in particular by Wagner, et al. ""The theory exists that any reduction in the volume of umbilical cord blood units in albumin or dextran prior to transfusing into patients leads to better cell viability. The mother will be informed about the status of the blood unit and the test results so that she is aware of any infection or disease that might affect her baby. Many parents see placental and cord blood banking as valuable tools to help them secure potentially ...From:fivespanishViews:0 0ratingsTime:01:18More inScience Technology

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PHILADELPHIA As researchers work on reconfiguring cells to take on new regenerative properties, a new review from Penn Medicine plastic surgeons sheds additional light on the potential power of adipose-derived stem cells - or adult stem cells harvested from fatty tissue - in reconstructive and regenerative medicine.

Reconstructive plastic surgeons have clinically integrated "fat grafting" into different surgeries for years, for breast, facial, and other reconstructive and restorative surgeries, with good success. Now, researchers are beginning to understand the power that fatty tissue holds. This new paper, published in the Aesthetic Surgery Journal, enforces that adipose-derived stem cells can be routinely isolated from patients and, once molecular methods are worked out, may be useful for a multitude of regenerative medicine applications.

"The opportunities for regenerative medicine interventions based on adult stem cells are tremendous. It is critically important for us to better understand the biology of these cells so that we can develop novel, safe and effective treatments for our patients using their own cells." said the paper's senior author, Ivona Percec, MD, PhD, assistant professor in the division of Plastic Surgery in the Perelman School of Medicine at the University of Pennsylvania.

Many groups are looking into different modes of isolating and modifying these cells for their regenerative properties, including experts at Penn's Institute for Regenerative Medicine and around Penn Medicine. For example, Dr. Percec's team is conducting translational research into the mechanisms controlling adipose-derived stem cells, and how they contribute to the normal human aging process.

Stem cells can undergo multiple divisions without differentiation, making them useful tools for cell-replacement therapy. Embryonic stem cells can convert to any cell type, whereas adult stem cells, like the stem cells derived from fat, can differentiate into many, but not all, cell types. A person's own fat tissue could then potentially be converted into cells specially designed to repair damage to the heart, cartilage, blood vessels, brain, muscle, or bone.

As regenerative medicine techniques are refined, experts will continue to explore the utility and benefits of stem cells derived from adipose tissue.

The Perelman School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $479.3 million awarded in the 2011 fiscal year.

The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; and Pennsylvania Hospital the nation's first hospital, founded in 1751. Penn Medicine also includes additional patient care facilities and services throughout the Philadelphia region.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2011, Penn Medicine provided $854 million to benefit our community.

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R. Bolli - Interim Results of the SCIPIO Trial Up to 2 Years After Therapy
R. Bolli - Effect of Cardiac Stem Cells in Patients with Ischemic Cardiomyopathy: Interim Results of the SCIPIO Trial Up to 2 Years After Therapy SCIPIO: (Cardiac) Stem Cell Infusion in Patients with Ischemic cardiomyopathy Annual Session of the American Heart Association November 5, 2012, Los AngelesFrom:CardioletterViews:0 0ratingsTime:09:07More inScience Technology

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R. Bolli - Interim Results of the SCIPIO Trial Up to 2 Years After Therapy - Video

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By E.J. Mundell HealthDay Reporter

TUESDAY, Nov. 6 (HealthDay News) -- Updated two-year results from a small trial using cardiac stem cells to repair damaged hearts suggest the treatment's healing effect persists.

Patients with heart failure caused by prior heart attacks who got the treatment continue to see reductions in cardiac scar tissue, improvements in the heart's pumping ability and even a boost in their quality of life, researchers said.

These improvements seem to be continuing as time goes on, suggesting that stem cell therapy's healing power hasn't diminished.

"Now we need to perform larger and randomized, blinded studies ... to confirm this data," said study lead author Dr. Roberto Bolli, director of the Institute of Molecular Cardiology at the University of Louisville.

His team presented its results Tuesday at the American Heart Association's annual meeting, in Los Angeles.

According to the AHA, more than 6 million Americans suffer from heart failure, a gradual weakening of the heart often caused by damage from a prior heart attack. Despite its prevalence and lethality, virtually no advance has been made over the past few decades in doctors' ability to treat or reverse heart failure.

That's why the advent of stem cell therapy has encouraged researchers. Stem cells have the ability to turn into myriad living cells, and the hope is that once infused into the heart they can help repair it.

This trial is the first human trial to test this theory using the patient's own cardiac stem cells. The cells used in the trial were harvested from 33 heart failure patients who were undergoing bypass surgery. The cells were then coaxed to multiply into the millions in the lab and then transplanted back into 20 of the patients. The remaining 13 patients did not receive a stem cell infusion and are the "control" group for comparison purposes.

Results gathered one year after treatment showed improvements for the treated patients, but experts questioned whether those gains would fade over time.

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Two Years On, Stem Cells Still Healing Damaged Hearts

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Study Highlights:

LOS ANGELES, Nov. 6, 2012 (GLOBE NEWSWIRE) -- Cardiac stem cells may one day be an effective treatment for heart failure caused by muscle scarring after a heart attack, according to late-breaking clinical trial results presented at the American Heart Association's Scientific Sessions 2012.

In the Effect of Cardiac Stem Cells In Patients with Ischemic CardiOmyopathy (SCIPIO) trial, heart function and quality of life improved in 20 people treated with their own cardiac stem cells (CSCs).

"This is exciting," said Roberto Bolli, M.D., lead author of the trial, chief of Cardiovascular Medicine and director of the Institute of Molecular Cardiology at the University of Louisville in Kentucky. "The effect of these cells has continued for up to two years, and has gotten stronger. There was also a major reduction in heart scarring."

In 33 patients with heart failure who had undergone coronary artery bypass surgery, researchers removed a tiny piece of heart tissue and isolated heart stem cells called c-kit CSCs. Researchers then grew additional cells to infuse into 20 volunteers assigned to treatment.

Among outcomes found two years after treatment:

"We have not seen any deaths among the patients, or any adverse effects that can be ascribed to the stem cells," Bolli said.

About 6.6 million Americans suffer from heart failure, according to the American Heart Association. Life expectancy is about five years after diagnosis. Ischemic heart attacks cause most of the 57,000 U.S. deaths a year due to heart failure.

Larger, multi-center studies are needed to confirm the findings, Bolli said.

The Jewish Hospital, University of Louisville, and the National Institutes of Health funded the study. Co-authors' names are on the abstract.

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Cardiac Stem Cells May Help Treat Heart Failure

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