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$4.8 Billion Worldwide Nucleic Acid Isolation and Purification Industry to 2025 – Impact of COVID-19 Pandemic – PRNewswire

DUBLIN, June 22, 2020 /PRNewswire/ -- The "Nucleic Acid Isolation and Purification Market by Product (Kit, Reagent, Instrument), Method (Column, Magnetic Beads), Type (Genomic DNA, Plasmid DNA, miRNA), Application (Drug Discovery, Precision Medicine), End User (Academic) - Global Forecast to 2025" report has been added to ResearchAndMarkets.com's offering.

The global nucleic acid isolation and purification market is projected to reach USD 4.8 billion by 2025 from USD 3.2 billion in 2020, at a CAGR of 8.9% during the forecast period.

The major factors driving the growth of the market include increasing R&D activities as well as technological advancements and increasing automation. However, the high cost of automated instruments is expected to hinder the growth of the market.

The instruments segment will grow at the highest rate during the forecast period.

On the basis of product, the nucleic acid isolation and purification market are segmented into kits, reagents, and instruments. In 2019, kits were the largest product segment in the market. Growth in this market can be attributed to the continuous focus of key market players on developing and launching new and advanced kits. However, the instruments segment is expected to grow at the highest rate during the forecast period.

By type, the plasmid DNA isolation and purification segment accounted for the largest share of the nucleic acid isolation and purification market in 2019.

On the basis of type, the global nucleic acid isolation and purification market are segmented into plasmid DNA isolation and purification, total RNA isolation and purification, circulating nucleic acid isolation and purification, genomic DNA isolation and purification, messenger RNA isolation and purification, microRNA isolation and purification, PCR cleanup, and other nucleic acid isolation and purification types. The plasmid DNA isolation segment accounted for the largest share of the nucleic acid isolation and purification market in 2019. The large share of this market segment can be attributed to the wide use of purified plasmid DNA in a variety of downstream applications, such as PCR, sequencing, expression of proteins, gene therapy, and transfection.

The market in the Asia Pacific is projected to witness the highest growth rate during the forecast period (2020-2025).

North America accounted for the largest share of the nucleic acid isolation and purification market in 2019. Significant R&D spending in biotechnology and pharmaceutical companies, the large size of the biotechnology industry, technological advancements, and government support in the region are the key factors driving the growth of the nucleic acid isolation and purification market in North America. On the other hand, the Asia Pacific is projected to register the highest growth during the forecast period. This large share can be attributed to factors such as the increasing number of genomic projects and increasing R&D investments by pharmaceutical & biotechnology companies in this region.

Key Topics Covered:

1 Introduction

2 Research Methodology

3 Executive Summary

4 Premium Insights 4.1 Nucleic Acid Isolation and Purification Market Overview 4.2 North America: Nucleic Acid Isolation and Purification Market, by Product (2019) 4.3 Geographical Snapshot of the Nucleic Acid Isolation and Purification Market

5 Market Overview 5.1 Market Dynamics 5.1.1 Drivers 5.1.1.1 Increasing R&D Activities 5.1.1.2 Technological Advancements and Increasing Automation 5.1.2 Restraints 5.1.2.1 High Cost of Automated Instruments 5.1.3 Opportunities 5.1.3.1 High Scope of Growth in Emerging Economies 5.1.3.2 Improving Regulatory and Reimbursement Scenario 5.1.3.3 Molecular Diagnostics and Personalized Medicine 5.1.4 Trends 5.1.4.1 Impact of the Covid-19 Pandemic 5.1.4.2 Increase in Government Funding

6 Nucleic Acid Isolation and Purification Market, by Product 6.1 Introduction 6.2 Kits 6.2.1 Kits Were the Largest Product Segment in the Market in 2019 6.3 Reagents 6.3.1 Reagents Segment to Grow at a Steady Rate During The Forecast Period 6.4 Instruments 6.4.1 Automated Instruments Enable a Faster, Cleaner, and More Consistent Nucleic Acid Extraction Process

7 Nucleic Acid Isolation and Purification Market, by Method 7.1 Introduction 7.2 Column-Based Isolation and Purification 7.2.1 Column-Based Isolation and Purification Was the Largest Segment in the Market in 2019 7.3 Magnetic Bead-Based Isolation and Purification 7.3.1 Magnetic Bead-Based Isolation and Purification Segment to Register the Highest CAGR During the Forecast Period 7.4 Reagent-Based Isolation and Purification 7.4.1 Reagent-Based Isolation and Purification Segment to Register Steady Growth During the Forecast Period 7.5 Other Isolation and Purification Methods

8 Nucleic Acid Isolation and Purification Market, by Type 8.1 Introduction 8.2 Plasmid Dna Isolation and Purification 8.2.1 Plasmid Dna Isolation and Purification Accounted for the Largest Share of the Market 8.3 Total Rna Isolation and Purification 8.3.1 Total Rna Isolation and Purification Segment to Register Steady Growth 8.4 Genomic Dna Isolation and Purification 8.4.1 Genomic Dna Isolation is the First Step in Genetic-Based Tests 8.5 Messenger Rna Isolation and Purification 8.5.1 Messenger Rna Isolation and Purification is Mainly Used in the Study of Gene Expression and Transcriptomics 8.6 Circulating Nucleic Acid Isolation and Purification 8.6.1 Clinical Applications to Drive the Market for Circulating Nucleic Acid Isolation and Purification 8.7 Microrna Isolation and Purification 8.7.1 Microrna Kits Provide Rapid Isolation and Purification of Rna Molecules from Samples 8.8 Pcr Cleanup 8.8.1 Time-Consuming Laboratory Procedures to Limit the Growth of this Market During the Forecast Period 8.9 Other Nucleic Acid Isolation and Purification Types

9 Nucleic Acid Isolation and Purification Market, by Application 9.1 Introduction 9.2 Diagnostics 9.2.1 Diagnostic Applications Form the Largest and Fastest-Growing Segment in the Market 9.3 Drug Discovery & Development 9.3.1 Ngs Benefits Drug Discovery Applications in Various Therapeutic Areas 9.4 Personalized Medicine 9.4.1 Rising Incidence of Cancer and Increasing Research and Funding to Drive the Market for this Segment 9.5 Agriculture & Animal Research 9.5.1 Favorable Funding Scenario to Support Market Growth 9.6 Other Applications

10 Nucleic Acid Isolation and Purification Market, by End-user 10.1 Introduction 10.2 Hospitals & Diagnostic Centers 10.2.1 Availability of Genetic Tests and Rising Focus on Personalized Medicine in Hospitals to Drive Market Growth 10.3 Academic & Government Research Institutes 10.3.1 Increase in Research Intensity to Drive the Usage of Nucleic Acid Isolation and Purification Systems 10.4 Pharmaceutical & Biotechnology Companies 10.4.1 Increasing Number of Research Projects in Genomics and Related Areas is Expected to Drive the Market 10.5 Contract Research Organizations 10.5.1 Contract Research Organizations Are Expected to Register Steady Growth During the Forecast Period 10.6 Other End-users

11 Nucleic Acid Isolation and Purification Market, by Region 11.1 Introduction11.2 North America11.2.1 US11.2.1.1 Government and Private Funding to Support Market Growth in the Us11.2.2 Canada11.2.2.1 Demand for Nucleic Acid Isolation and Purification in Canada is Increasing Primarily Due to Growing Investments in Genomics11.3 Europe11.3.1 Germany11.3.1.1 Germany is the Largest Market for Nucleic Acid Isolation and Purification in Europe11.3.2 UK11.3.2.1 Government Support for Research in the Form of Investments, Funds, and Grants to Support Market Growth11.3.3 France 11.3.3.1 High Cancer Burden in France to Drive Market Growth 11.3.4 Roe 11.4 Asia-Pacific 11.4.1 China 11.4.1.1 China to Register the Highest Growth in the Nucleic Acid Isolation and Purification Market in APAC 11.4.2 Japan 11.4.2.1 Japan to Register Steady Growth During the Forecast Period 11.4.3 India 11.4.3.1 Strong Growth Trends in the Pharmaceutical & Biotechnology Industries to Drive the Market in India 11.4.4 Roapac 11.5 Rest of the World 11.5.1 Latin America 11.5.1.1 to Prevent Cancer Mortality, the Brazilian Government Recommends Screening Programs for Breast and Prostate Cancer 11.5.2 Middle East & Africa 11.5.2.1 Lack of Infrastructure for Research to Hamper the Growth of the Naip Market in the Middle East & Africa

12 Competitive Landscape 12.1 Introduction 12.2 Market Evaluation Framework 12.3 Revenue Analysis of Top Market Players 12.4 Competitive Scenario 12.4.1 Collaborations & Agreements 12.4.2 Product Launches & Approvals 12.4.3 Acquisitions 12.4.4 Expansions

13 Company Evaluation Matrix and Company Profiles 13.1 Company Evaluation Matrix 13.1.1 Market Share Analysis 13.2 Competitive Leadership Mapping (Overall Market) (2019) 13.2.1 Stars13.2.2 Emerging Leaders 13.2.3 Pervasive Players 13.2.4 Emerging Companies

14 Company Profiles 14.1 Qiagen N.V. 14.2 Thermo Fisher Scientific 14.3 F. Hoffman-La Roche AG 14.4 Promega Corporation 14.5 Agilent Technologies 14.6 Bio-Rad Laboratories 14.7 Danaher Corporation 14.8 GE Healthcare 14.9 Illumina 14.10 Merck Kgaa 14.11 Takara Bio, Inc. 14.12 New England Biolabs 14.13 Zymo Research 14.14 Norgen Biotek 14.15 Omega Bio-Tek, Inc. 14.16 Other Companies 14.16.1 Genaxxon Bioscience GmbH 14.16.2 3B Blackbio Biotech India Ltd. 14.16.3 Invitek Molecular GmbH 14.16.4 Biovision 14.16.5 Analytik Jena AG

15 Appendix

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$4.8 Billion Worldwide Nucleic Acid Isolation and Purification Industry to 2025 - Impact of COVID-19 Pandemic - PRNewswire

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Global Covid-19 impact on CELL CULTURE MEDIA Market 2020 Latest Technology, Size, Growth Opportunities, Research Analysis and Forecast – Cole of Duty

A new research study has been presented by Precision Market Reports (PMR) after a comprehensive analysis on CELL CULTURE MEDIA Market where user can get benefits from the complete market research report with all required useful information on market. Report discuss all major market aspects with expert opinion on current market status along with historic data as well. Detailed study Price, Share, Size & Growth, Latest News & Developments, Expansion Plan, Current Business Strategy, Top Companies, Sales, Revenue & Competitors Analysis, Production and Consumption, Demand & Supply, Industry and Business Study, Effect of Covid 19 (Buyers & Sellers) and Prediction 2020-2025.

Regions Covered in the CELL CULTURE MEDIA Market:

Covid-19 Scenario:

Since the COVID-19 virus outbreak in December 2019, the disease has spread to almost 100 countries around the globe with the World Health Organization declaring it a public health emergency. The global impacts of the corona virus disease 2019 (COVID-19) are already starting to be felt, and will significantly affect the market in 2020. COVID-19 can affect the global economy in three main ways: by directly affecting production and demand, by creating supply chain and market disruption, and by its financial impact on firms and financial markets.

Top Players & Competitive Analysis (Benefits) for CELL CULTURE MEDIA:

A competitive analysis is a strategy where we identify major competitors and research their products, sales, and marketing strategies. By doing this, you can create solid business strategies that improve upon your competitors. A competitive analysis helps you learn the ins and outs of how your competition works. It also helps you identify what theyre doing right and opportunities where you can easily one-up them by using a strategy they havent taken advantage of.Every brand can benefit from regular competitor analysis. By performing a competitor analysis, youll be able to:

As you can see, learning any of these four components will lead your brand down the path of achievement. But before you get too excited to start, we need to nail down a few important basics.

Once you identify your true competition, youll need to determine what metrics youll be comparing across the board. Below, well give nine specific factors to compare and tips on how to identify this competition in the first place.

CELL CULTURE MEDIA Competitors Analysis includes market shares for all the companies listed below, Competitors Analysis revenue chart, Competitive Dashboard, and the competitors latest strategies for overcoming the Covid 19 pandemic situation.

Get A PDF Sample of CELL CULTURE MEDIA Report: https://www.precisionmarketreports.com/download-sample/294015

SEGMENTAL ANALYSIS:

Business segment reporting breaks out a companys financial data by company divisions,subsidiaries, or other kinds of businesssegments. In an annual report, business segment reporting provides an accurate picture of apublic companysperformance to its shareholders. Management uses business segment reporting to evaluate the income, expenses, assets, and liabilities of each business division to assess its general healthincluding profitability and potential pitfalls.

Asegmentis a component of a business that generates its ownrevenuesand creates its own product, product lines, or service offerings.In general, if a unit of a business can be lifted out of the larger company and remain a self-sufficient entity, then it may be classified as a business segment.

By ApplicationBiopharmaceutical Manufacturing, Tissue Culture & Engineering, Gene Therapy, Cytogenetic

By TypeClassical Media & Salts, Serum-free Media, Stem Cell Media

By Life TechnologiesBD, Thermo Fisher, Corning (Cellgro), Lonza, Sigma-Aldrich, Takara, GE Healthcare, Merck Millipore, HiMedia

By CellGenixZenbio, Atlanta Biologicals, PromoCell

The prime objective of this report is to help the user understand the market in terms of its definition, segmentation, market potential, influential trends, and the challenges that the market is facing. Deep researches and analysis were done during the preparation of the report. The readers will find this report very helpful in understanding the market in depth. The data and the information regarding the market are taken from reliable sources such as websites, annual reports of the companies, journals, and others and were checked and validated by the industry experts. The facts and data are represented in the report using diagrams, graphs, pie charts, and other pictorial representations. This enhances the visual representation and also helps in understanding the facts much better.

KEY TAKEAWAYS:

Get PDF Sample Copy of the Report to understand the structure of the complete report: (Including Full TOC, List of Tables & Figures, and Chart) @: https://www.precisionmarketreports.com/download-sample/294015

What Reports Provides:

Table of Contents:

1.1 Research Scope

1.2 Market Segmentation

1.3 Research Objectives

1.4 Research Methodology

1.4.1 Research Process

1.4.2 Data Triangulation

1.4.3 Research Approach

1.4.4 Base Year

1.5 Coronavirus Disease 2019 (Covid-19) Impact Will Have a Severe Impact on Global Growth

1.5.1 Covid-19 Impact: Global GDP Growth, 2019, 2020 and 2021 Projections

1.5.2 Covid-19 Impact: Commodity Prices Indices

1.5.3 Covid-19 Impact: Global Major Government Policy

1.6 The Covid-19 Impact on CELL CULTURE MEDIA Industry

1.7 COVID-19 Impact: CELL CULTURE MEDIA Market Trends

2 GLOBAL CELL CULTURE MEDIA QUARTERLY MARKET SIZE ANALYSIS

2.1 CELL CULTURE MEDIA Business Impact Assessment COVID-19

2.1.1 Global CELL CULTURE MEDIA Market Size, Pre-COVID-19 and Post- COVID-19 Comparison, 2020-2025

2.2 Global CELL CULTURE MEDIA Quarterly Market Size 2020-2021

2.3 COVID-19-Driven Market Dynamics and Factor Analysis

2.3.1 Drivers

2.3.2 Restraints

2.3.3 Opportunities

2.3.4 Challenges

3 QUARTERLY COMPETITIVE ASSESSMENT, 2020

3.1 By Players, Global CELL CULTURE MEDIA Quarterly Market Size, 2019 VS 2020

3.2 By Players, CELL CULTURE MEDIA Headquarters and Area Served

3.3 Date of Key Players Enter into CELL CULTURE MEDIA Market

3.4 Key Players CELL CULTURE MEDIA Product Offered

3.5 Mergers & Acquisitions, Expansion Plans

Any query? Enquire Here for Discount (COVID-19 Impact Analysis Updated Sample): https://www.precisionmarketreports.com/download-sample/294015

The study points out the limitations that aim to overcome the challenges to massive success for companies. Through means of this study, customers can conveniently obtain views on the CELL CULTURE MEDIA market based on the current scenario.

What is the Impact of Covid-19 Outbreak on the Online Remote Proctoring (Remote Invigilation)?

About Precision Market Reports (PMR):

Precision Market Reports provides quantified B2B research on 25,000 high-growth niche opportunities / threats that will impact 50 to 75 percent of global company revenues. Actively representing more than 5000 customers worldwide, including 50 percent of Fortune 500 global businesses as clients. Almost 25,000 top officials across eight industries worldwide approach Precision Market Reports for their pain points around revenue decisions.

Our reports provide a rare combination of concrete perspectives and qualitative research to help businesses attain sustainable growth. Our team of experienced analysts and consultants use industry-leading research tools and techniques to compile extensive, interspersed with relevant data, market studies.

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Global Covid-19 impact on CELL CULTURE MEDIA Market 2020 Latest Technology, Size, Growth Opportunities, Research Analysis and Forecast - Cole of Duty

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Flames assistant GM continues to defy the odds in his battle against ALS – CTV News

CALGARY -- After being diagnosed with ALS, Calgary Flames assistant general manager Chris Snow appreciates every minute he gets to spend with his family.

He never takes it for granted.

He also appreciates recent fundraising efforts similar to the Ice Bucket Challenge that have been taking social media by storm, in his honour.

On Monday Snow was tossing the ball around with his children, eight year old Cohen and five year old Willa.

Just over a year ago, he didnt think he was going to be able to do that.

He says hell never forget that day, when a doctor told him he had ALS.

"He looked at me and said this is the early stage and you just sink," he said.

"You think your life is over because it really is. At least until now, in every case, it's a no hope disease."

About 3,000 Canadians currently live with ALS. Its a rapid and always fatal neurodegenerative disease that typically hits those aged between 55 and 65.

Chris is just 38 years old and ALS runs in his family. His dad, two uncles and a cousin all passed away from it.

The Snows have the most aggressive sub-type of the disease. Chris was given just 12 months to live.

But he and his wife Kelsie werent about to give up. Kelcie did the research and Chris was enrolled in a gene therapy clinical trial.

Kelcie says that gave them hope.

You know when I asked the doctor, 'is it possible this could stop their progression entirely?' and he said, 'we dont know but its not outside the realm of possibility,'" she said.

"We held onto that and we keep holding onto that."

Chris says so far its appears to be working.

My right hand, it doesnt really do anything for me. But it hasnt since I enrolled in the trials. I didnt see that as a form of progression because that was already gone," he said.

My upper arm on that side remains very strong. I can lift and hold my kids with that. Just have to catch them right way.

June is ALS awareness month. And Snow and the Flames came up with a unique idea to help raise money to fight the disease.

Its called Trick Shot for Snowy and has taken twitter by storm. Snow says hes been loving all of the creativity.

Its like the ice bucket challenge but its fun," he said. "You get to show off a little bit. And do things that are either skillful or ridiculous. And social media has the ability to reach so many people at this point in time."

So far, Trick Shot for Snowy has raised more than $150,000. Chris says all the money raised will be put toward the best research they can find in Canada.

Kelcie says she couldnt be more proud of her husband.

You know in some ways its like he was made for something like this," she said. "Hes so positive and he always finds a way to get by and to keep going and smiling."

Just over a year ago Snow thought he was given a death sentence. On Sunday, Fathers Day, he hiked a mountain with his family.

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Flames assistant GM continues to defy the odds in his battle against ALS - CTV News

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3 Reasons to Go Long Crispr Therapeutics – InvestorPlace

For years, I consistently urged investors to focus the bulk of their portfolios on what I term megatrends. While making a quick buck on momentum plays is great, your highest probabilities of success rest on long-term developments in technology and innovation. And few hit all the right buttons like Crispr Therapeutics (NASDAQ:CRSP). Levered to the groundbreaking gene-editing industry, CRSP stock deserves extra attention for anyone interested in phenomenal gains.

Source: Catalin Rusnac/ShutterStock.com

Its amazing to think how far technology has come. What was once the exclusive realm of science fiction, we are now closer than ever to a fully automated society. From driverless vehicles to automated customer service platforms to smart city infrastructures, investing in innovation has never been more relevant.

At the same time, medical innovations have somewhat lagged the profound changes were seeing everywhere else. Try as we might, we havent had many breakthroughs regarding the human condition. Primarily, our practically available medical solutions involve mitigating symptoms, not addressing root causes. Crispr Therapeutics hopes to disrupt this paradigm entirely, thereby imbuing CRSP stock with its potential.

Underlining the biotechnology firms awe-striking platform is CRISPR, which is a specialized stretch of DNA. Associated with CRISPR is a protein called Cas9, which essentially acts as a pair of molecular scissors. This function enables the gene-editing process, which from a broad summary view involves cutting problematic gene sequences and correcting them.

One of the most important components of the CRISPR-Cas9 technology is that scientists adapted it from a naturally occurring genome editing system in bacteria. Thus, were not necessarily talking about playing God. Instead, were utilizing breakthroughs in biotechnology to transfer natural processes to aid humanity.

I couldnt think of a better argument for CRSP stock. But here are three more for your consideration.

In the biotech space, the biggest prize is the cure for cancer. By the end of this year, experts predict that 1.8 million Americans will be diagnosed with the disease. Tragically, over 600,000 will succumb to cancer. Thus, its imperative that we marshal all available resources to fight this scourge.

Unfortunately, the mechanisms by which we treat the disease is rather antiquated. Years from now, I can imagine that people will look back and consider our tactics barbaric. Rather than attacking the cancer cells themselves, we address symptoms, mainly through surgery, chemotherapy and radiation therapy.

In other words, cut em, drug em and fry em. That might work if were in the fake meat processing business. But to treat our loved ones, it seems crude and anachronistic.

And this is why Im very excited about the potential of CRSP stock. To be clear, Im not suggesting that Crispr is on the cusp of a cancer breakthrough. However, with their innovative approach modifying a patients immune cells to efficiently attack cancer cells the possibilities are simply astonishing.

Currently, the major knock against this platform is its extreme cost, which brings up ethical concerns. However, through industry partnerships and synergies, its likely that over time, these costs will come down, making them a more affordable choice for patients.

One of the worst pieces of bad news you can get from the doctor is a diagnosis of a rare disease. Unlike other conditions, such as cancer, support networks may be limited in number. In addition, the treatment options may be few as well. Plus, the available solutions are typically very expensive.

But the most difficult challenge is the helplessness that patients suffer. For instance, with lupus, the body basically attacks itself. Traditional medicines have focused on symptom mitigation. But what can you do when your body stands divided?

Its precisely this type of condition for which Crispr provides meaningful hope. With the companys gene-editing technology, it can potentially alter the lives of millions who suffer silently.

As with cancer, Crisprs current mechanism isnt cheap and therefore, isnt practical for all but the wealthiest patients. Again, though, advancing technologies always drive down costs. And frankly, having the foundation for such groundbreaking solutions is far better ethically than not having it whatsoever.

Therefore, I believe investors can buy into CRSP stock with a clear conscience.

Easily the most powerful yet controversial implication of the CRISPR-Cas9 technology is the development of gene drives. According to Live Science contributor Aparna Vidyasagar, gene drives are:

genetic systems, which increase the chances of a particular trait passing on from parent to offspring. Eventually, over the course of generations, the trait spreads through entire populations, according to theWyss Institute. Gene drives can aid in controlling the spread of diseases such as malaria by enhancing sterility among the disease vector

Where it gets tricky is this technologys potential to enhance or eliminate certain traits of parents to their offspring; Im talking of course about designer babies.

Obviously, this is a discussion that extends well beyond the scope of this article. However, I will say this: the possibility of improving the human condition is likely worth the risk of unintended consequences. Therefore, I remain bullish on CRSP stock despite some nuances associated with the underlying narrative.

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GRIN Disorder, Kidney Failure and Fathers Day How One Family is Surviving it All – CBC.ca

My life changed forever the day I became the father to a son with extreme special needs. But I could never have imagined just how much being Brysons dad would continue to change my identity. While our familys COVID-19 isolation has been challenging, it has provided me with the opportunity to reflect on the evolving nature of my role as father.

Happy Faw-vers Day.

My two-and-a-half-year-old son Connor stumbles toward me, carrying a gift almost as big as he is. I unwrap a PlayStation 2. Its a surprisingly expensive gift, but my wife Laura reminds me that this is a special Fathers Day. Shes seven months pregnant, and even though we havent met our second child, were already in love with the newest member of our family.

I thank Connor before leaning in close and kissing Lauras belly. Thank you, baby.

If you'd like to make your Father's Day crafty, have your little ones try a fun printable print it here.

Baby Brysons first year has been tough. Hes missed all his milestones and doctors have confirmed that he isnt developing typically. Hes 10 months old but cant sit independently, or crawl, or track objects with his eyes. Hes nowhere near being able to say his first word or take his first steps. But doctors dont know why.

When Connor was born, my identity changed. I was no longer just a guy. I was a father. Becoming a special needs dad has changed me once again. The responsibility feels weightier; theres less room for error. I need to get this right.

A few days before Fathers Day, we go out for dinner at an all-you-can-eat Asian restaurant. The food is tasty but the service is slow. And Bryson is loud. Theres this sound he makes that we call singing but its really more of a happy wail. Were accustomed to it, but the diners around us are not. Someone complains and a manager drops by our table.

"You need to tell your son to be quiet," she says, waving at Bryson. "Other guests are complaining."

"My single greatest fear is whos going to protect him when Laura and I arent around."

We ask her to pack up our food and we head home, full of sadness and fear for Brysons future. Once hes in bed, I sit down and type out what I call my Fathers Day pledge, to be by his side to protect him from the judgments of this world until the day I die.

My single greatest fear is whos going to protect him when Laura and I arent around.

You can listen to Keith McArthur and Bryson's story in his podcast Unlocking Bryson's Brainright now. Listen here.

This ones hard. My own father died of cancer a couple months earlier. Theres this massive hole in my life that cant be filled, and on Fathers Day, it feels particularly unbearable. Ive become so depressed over the past couple of months that I cant seem to handle life anymore. I find myself leaving my desk at work and sneaking off to my car to hide, sometimes for hours.

Fears about Bryson are also weighing heavily. Hes almost eight but he cant walk or talk. His brain seems to be locked at the developmental age of 12 months. He also has violent episodes where he hurts himself and those around him. Hopes that he might just grow out of this are a distant memory. Doctors have performed so many tests dozens of blood draws, MRIs, muscle biopsies but they cant figure out whats causing Brysons condition.

I love Bryson so much, but I cant help wondering if hes even capable of loving back.

It all feels too hard. I promise Laura Ill see a doctor about my depression. Two weeks later Im on anti-depressants. Life isnt easy, but at least its manageable again.

Were celebrating Fathers Day in a hotel room in suburban Pittsburgh. Connor hands me some gifts, including a barbecue cookbook and a broken picture frame, the casualty of an overpacked suitcase and a six-hour road trip.

Our lives have changed dramatically over the past two years. I got off the anti-depressants, then experienced kidney failure, then got a second chance at life when my sister Stephanie donated one of her kidneys to me.

And after nearly a decade of searching, we finally got a diagnosis for Bryson. A genetic sequencing test revealed that Bryson has a mutation in his GRIN1 gene one of several genes that encode receptors in the brain that play a critical role in learning and memory. Pathogenic variants in this cluster of genes are known as GRIN Disorder.The diagnosis is why were here in Pittsburgh, meeting other GRIN Disorder families from across the country. Bryson is no longer alone.

Weve agreed to host this years GRIN family conference in Toronto, so I spend Fathers Day finalizing plans. Families travel in from across North America and we line up a panel of scientists who can help us understand this rare disease. Im shocked when they tell us that a cure for GRIN Disorder might be possible. Bryson is perfect; I dont want to change him. But if new treatments could allow him to communicate and make more of his own decisions, wouldnt he want that?

My paternal identity changes once again. Im no longer just a father or a special needs dad, but a rare disease warrior putting my life on hold to chase down a cure. I make a podcast series about this journey. Unlocking Brysons Brain launches two years later in the midst of a global pandemic.

The world is slowly getting back to normal but not for my family. GRIN Disorder usually isnt fatal, but some GRIN kids have died suddenly from respiratory complications. Im also on post-transplant drugs that lower my immune system. We cant risk allowing COVID-19 into our family, so well be spending this Fathers Day much as we have spent the past three months in isolation.

Brysons medical appointments are all on hold. So is the physio and speech therapy he usually gets through school. And the Grade 8 graduation ceremony Id been looking forward to for years? Its not happening this year. Worse still, all the research Ive been pushing to help find a cure is on hold as labs that arent focused on COVID-19 shut their doors.

On the plus side, pandemic life means more family time. And on a cloudy weekend in May, my son Bryson delights me with two early Fathers Day gifts.

Bryson does well in his walker at school, but hes been struggling at home. He just plops down on the safety seat instead of moving forward. So Laura has an idea. She removes the seat. And suddenly Bryson takes off, walking better than Ive ever seen him move before. Its the best gift I could hope for.

"We cant risk allowing COVID-19 into our family...."

But theres a bigger one yet to come.

Bryson loves it when I kiss him on the left side of the neck, just under his ear. When he wants me to do this he puts his hands on the back of my head and pulls me close. But this time, he pulls me in close and, for the first time, starts kissing my face. The kisses are wet and toothy, and make both of us erupt with laughter.

And they are unmistakable acts of love.

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GRIN Disorder, Kidney Failure and Fathers Day How One Family is Surviving it All - CBC.ca

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A geneticist advocates for diversity and fixing his industry in the process – STAT

Over the past few weeks, 23andMe and other genetic testing companies have made headlines for releasing candid statements acknowledging that their field and their products are too white. Its a problem with which geneticist Tshaka Cunningham is all too familiar.

As executive director of the nonprofit Faith Based Genetic Research Institute, Cunningham has traveled widely to speak at Black churches about the value of genetic research. And as co-founder and chief scientific officer of a genetics startup called TruGenomix, hes working to recruit more diverse cohorts to build a genetic test for gauging risk of developing PTSD.

Cunningham recently called in to STATs podcast, The Readout LOUD, to discuss genetics and racial inequity and what needs to be done to make the field actually reflect the worlds diversity.

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The transcript of the conversation has been lightly edited for clarity.

So, Tshaka, what do you make of the reckoning that weve seen in the past couple weeks from 23andMe and other genetics companies on these issues?

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You know, I think its actually a really good thing. I was glad to see it from the highest levels from these companies acknowledging an issue that many of us in the research community have known about for quite a long time, which is this lack of representation of diverse genomes in all of our studies and products. Im glad its starting to get deeper attention because I think it is a key issue thats going to impact the effectiveness of all of these tools over time.

Im looking forward to seeing some positive things that they will do to address it. So, you know, the first step is admitting you have a problem and then you go through the steps to rehabilitate. Im hoping that some positive things will come out of this.

What kinds of questions about genetics do you hear from the communities you speak with?

All kinds of questions. And first of all, I say, you know, the work that were doing with the Faith Based Genetic Research Institute is very unique in that we are bringing together individuals from the faith communities with scientists who are also people of color, and one of our guiding principles in the work that we do in the community is called the honest broker philosophy. That is, those of us who are imparting the information to the community are also from the community. And what we found is that it really helps us establish a better bond of trust for folks to be able to receive the information.

Some of the questions that we get when we talk about the value and the benefits of genetic research is the first questions are, you know, are they going to use it to hurt me? Thats the first question we get a lot from African American participants. And, you know, what will they do with the information? Theres a fair bit of distrust out there. And some of it is quite warranted from past transgressions of the medical establishment on the African American community. But once you sort of talk through those issues with folks and really kind of allow them to see some of the potential benefits, then you start getting a high level of interest.

So lets say 23andMe, for example, or one of the large companies, were to call you and ask for advice on what to do to make their products less Eurocentric and more inclusive. What would you tell them?

Start by making sure that your team, your executive team specifically, is representative of the community. A lot of companies sort of say, well, we cant find them. Any company needing to find a talented minority geneticist give me a call. Ive got a long list.

The second step would be to really use some of your resources to sponsor more research in this area. I mean, part of the challenge is also a financial and economic challenge. When you think about the economic disparities that have existed in America based on racial lines you know, the average African American has seven times less wealth than the average Caucasian. So they might not have even a hundred bucks to spend on something like genetic testing that could benefit them.

And then theres also the messaging. I think to the extent that these companies could help organizations like ours, the Faith Based Genetic Research Institute, other academic institutions, with messaging about the importance or the potential benefits of this, that would be great.

Now, I know thats a fine line that they have to walk because, you know, you dont want to seem coercive. But at the same time, I think trying to really do authentic outreach to the community would start with having more of your employees be from the community and then having a dedicated effort of that kind of outreach within your operation.

One of the more controversial questions in this conversation is around compensation. So what do you think? Do you think that 23andMe should pay people in the Black community and other underrepresented populations for their data?

I believe anybody that contributes their data should have the opportunity to get paid for it if its used. I do not believe in coercing someone to contribute their data with payment. But if Im an individual who has contributed and then you go and use my my data lets say a pharma company buys access to my data and I dont see any benefit from it, then that feels a bit un-American and I just dont feel like its fair. But thats my personal opinion.

So lets talk a little bit about polygenic risk score tests, which really encapsulate the diversity problems in genetics. So, for readers who are unfamiliar with them, these are tests that gather multiple genetic variants together and use them to predict someones chances of developing a disease. So far, many commercial polygenic risk score tests have come off warnings that theyre not very accurate or are even useless in people who are not of European ancestry. But your startup, TruGenomix, is working on a polygenic risk score test to try to gauge risk for developing PTSD. And youre trying to build the test using more diverse data. Tell us about your approach.

Ive recognized the importance of diversity in your datasets. From my earliest days, when I was at the Department of Veterans Affairs, we had a large genomics project called the Million Veteran Program. And part of my contribution to that project was to make sure that minority veterans participated. And so we actually went to great effort to ensure that. And that project has done very well to the credit of the VA, to recruit minority veterans. So that data set is going to provide some rich understanding, or has that potential to provide rich understanding, in polygenic risk for minority communities.

I took some of what I learned there from having to really take the time to do the outreach to the communities, to make sure that the end products are representative. I think that is just core to our actual DNA as a company. I think part of that has to do with the fact that were one of the very few minority-owned genomics companies in the country right now. This was top of mind for us. We wanted to make sure that whatever products we were putting out, the polygenic risk related to all communities, specifically the African American community, which my founders and I come from. It was just a very important thing for us to do not only for societal and ethical reasons, but also for scientific integrity reasons, because as a scientist, I dont believe in putting out products that arent probably applicable to all communities.

So why havent other makers of polygenic risk score tests taken this more holistic approach?

You know, I cant speak for them. I mean, I dont know. Thats a question that I have. I would hope that they take a deeper look at it. Maybe their market calculations were, OK, the people using genetic tests now tend not to be people of color. And therefore, we dont need to care about them. I dont know. Youll have to ask them that question.

All I could say is that I hope that all of the companies that are making these kinds of tests really take diversity seriously. Ive given lectures around diversity and genetics in the past. The majority of the DNA in the world is not of Caucasian origin. Its actually of Asian origin. And then African and Latino. And then Caucasians are only maybe about 14% of all the DNA out there just based on population. So when you think about it in that respect, if you really want to have a genome that is globally applicable, then youd really need to focus on its diversity.

Tshaka, thank you for coming on the podcast today.

Great. Its great being with you all today.

Theresa Gaffney contributed to this report.

This is a lightly edited transcript from arecent episodeof STATs biotech podcast, The Readout LOUD. Like it?Consider subscribing to hear every episode.

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A geneticist advocates for diversity and fixing his industry in the process - STAT

Recommendation and review posted by Bethany Smith

Early-Onset Cancers Confer a High Risk of Harboring Germline Mutations – OncLive

Patients 18 to 39 years of age with early-onset cancer had a significantly high risk of harboring germline mutations, suggesting that this population should undergo germline genetic testing, irrespective of tumor type, according to results of a study that were presented during a press program ahead of the AACR Virtual Annual Meeting II.1,2

The results showed that 21% of patients with early-onset cancer (n = 877) had a germline mutation versus 13% of patients with young-adult cancer (n = 324; P = .002). The enrichment of high-and moderate-penetrance pathologic variants was 15% versus 10%, respectively (P = .01).

Among early-onset cancers, the most common mutations were BRCA1/2 (4.9%), Lynch syndromeassociated genes (2.2%), ATM (1.6%), and CHEK2 (1.7%), with pancreatic, breast, and kidney cancer harboring the highest rates of germline pathologic variants. Among young-adult cancers, the most common mutations were SDHA/B (1.9%) and TP53 (2.2%), the latter of which is consistent with Li-Fraumeni syndrome, which is known to be associated with childhood cancers, such as sarcoma.

This study highlights that genetic susceptibility among young cancer patients is heterogeneous, lead study author, Zsofia K. Stadler, MD, of Memorial Sloan Kettering (MSK) Cancer Center, stated in a press release. The distinct set of germline variants appear to suggest that patients with early-onset cancers harbor mutations similar to those also found in older individuals with cancer, but at a higher prevalence. Among patients with young-adult cancers, the mutations were more similar to those we encounter in our pediatric cancer patients.

Young adults with cancer, defined as those diagnosed between the ages of 18 to 39, represent only 4% of all cancers. However, with germline testing, providers can glean the risk of second primary cancers, the need for long-term surveillance aimed at early detection, risk-reducing surgery to prevent new cancers, and understand potential reproductive implications.

Identifying whether a young patients cancer occurred in the setting of an inherited cancer predisposition syndrome is important as it can result in a substantial change in clinical management, Stadler said during the presentation.

Moreover, germline testing results can help identify at-risk family members, including young siblings or children who should pursue genetic testing, and if positive, appropriate cancer screening or prevention measures.

To that end, investigators sought to quantify the prevalence of germline mutations in young patients with solid tumors. In the study, a total of 1201 blood samples were collected from patients who had been diagnosed with cancer at MSK between 2015 and 2019 and analyzed with the next-generation sequencing panel, MSK-IMPACT, which has the ability to sequence up to 88 genes that are known to be associated with cancer susceptibility.

Using The Surveillance, Epidemiology, and End Results data, investigators further divided patients into those with early-onset cancer, defined as cancer wherein age 39 was more than 1 standard deviation below the mean age of diagnosis for that cancer type and those with young-adult cancer, defined as cancer wherein age 39 was less than 1 standard deviation below the mean age at cancer diagnosis.

Additional results showed that the most common early-onset cancers (n = 877) included

colorectal (n = 179; 20%), breast (n = 342; 39%), kidney (n = 53; 6%), pancreatic (n = 50; 6%), and ovarian cancer (n = 50; 6%), whereas the most common young-adult cancers (n = 324) included sarcoma (n = 116; 36%), brain (n = 75; 23%), testicular (n = 57; 17%), and thyroid cancer (n = 30; 9%).

The mutation prevalence of sarcoma in young-adult patients with cancer was 18.1%, which was similar to the prevalence in patients with early-onset cancer.

Despite the increased prevalence of CHEK2 mutations in early-onset cancers, Stadler stated that these data do not support breast cancer screening earlier than is recommended for the general population in women with known CHEK2 mutations. Though, investigations are ongoing to determine whether these patients have a family history of breast cancer, in which case, screening before the age of 40 would be warranted.

In terms of insurance coverage for genetic testing in early-onset and young-adult cancers, Stadler explained that all patients with pancreatic cancer are now covered for germline genetic testing and expects that as the field broadens clinical guidelines for genetic testing, so too will coverage for the early-onset and young-adult patient populations.

1. Young adults with cancer may harbor germline mutations [news release]: Philadelphia, Pennsylvania. AACR. Published June 22, 2020. Accessed June 22, 2020.

2. Stadler Z, Maio A, Padunan A, et al. Germline mutations prevalence in young adults with cancer. Presented at: the 2020 AACR Virtual Annual Meeting II; June 22-24, 2020. Abstract 1122/4. bit.ly/2BlsMHS.

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Early-Onset Cancers Confer a High Risk of Harboring Germline Mutations - OncLive

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Everything You Need to Know About At-Home Testing Start-Ups 23andMe, Ancestry, and Everlywell – The Motley Fool

Genetic and diagnostic testing start-ups are at the forefront of providing health information as a service for consumers. As is frequently the case in emerging markets, no two testing start-ups have the same value proposition or strategic vision for growth.

Popular direct-to-consumer testing companies like 23andMe, Ancestry, and Everlywell have yet to go public, but investors who are keeping an eye on the future have much to consider. While these start-ups are private companies, any one of them could be headed toward an IPO in the coming years.

Image source: Getty Images.

23andMe is perhaps the most well-known genetic testing start-up, in part due to Google's (NASDAQ:GOOG) early investment of $3.9 million in 2007.

23andMe has two consumer-facing genetic test products: one that provides customers with information about their health risks and ancestry for $199, and another slightly less expensive product that only provides ancestry information. Both products require the customer to spit into one of 23andMe's collection tubes and then mail it back to the company's processing laboratory.

As of 2015, 23andMe also performs early stage therapeutics research. There are several signs that the company wants to expand its therapeutics division further. In 2018, 23andMe teamed up with GlaxoSmithKline (NYSE:GSK) to use its genetic datasets to discover new drug targets. Likewise, in January of this year, 23andMe announced that it had signed an agreement to license a therapeutic antibody candidate to Almirall (OTC:LBTS.F). If 23andMe can leverage its massive collection of consumer genetic data to develop new revenue streams from discovery partnerships for drug development, it will grow rapidly.

Ancestry is primarily a consumer-facing genealogy research company. Consumers who visit Ancestry's website use the company's software platform to perform public records searches and assemble family trees. The company's revenues come from a paid subscription service that has a larger feature set for genealogy research.

In service of its genealogy products, Ancestry developed its line of AncestryDNA genetic tests so that its customers could use their genetic information to find close relatives. Similarly to 23andMe, Ancestry's DNA service has a health-oriented testing package with optional add-ons and an ancestry-oriented testing package. But Ancestry's packages are less expensive, and customers must buy both products if they want both sets of genetic data. Ancestry outsources its sample processing to Quest Diagnostics (NYSE:DGX), limiting its costs.

So far, more than 15 million people are included in Ancestry's genetic database, but it's important to remember that the company's health-oriented testing package is less than a year old. Millions more people could flock to the platform if its genetic testing for health is less expensive or more understandable than the competition.

Everlywell is a diagnostic testing start-up that has a collection of more than 35 different tests that consumers can use to investigate everything from their food sensitivities to whether they have a sexually transmitted disease. Most of Everlywell's tests require a drop of blood via a finger prick apparatus rather than saliva, so some customers may perceive the tests to be more invasive. Critically, Everlywell's tests don't provide information about health risks on the basis of family history, nor do they offer other ancestry data.

Everlywell has a network of board-certified state-licensed physicians who review a customer's order to ensure the test they ordered is appropriate for them. If the physician approves the test to be sent out, the patient will take their own sample and mail it to a certified lab. The lab processes the test and sends a report to the physician who approves the results and sends them to Everlywell to be uploaded to the patient's online account. If the test is positive, the assigned physician will help the patient determine their treatment plan.

Nonetheless, as a testing-by-mail provider, Everlywell has shown remarkable product development agility. Everlywell has moved quickly to benefit from the pandemic by developing an at-home COVID-19 test product, which was the first from a digital health company to receive an emergency use authorization from the Food and Drug Administration. Either as a result of high demand or low manufacturing capacity, Everlywell currently restricts customers to purchasing one test per household. Given that COVID-19 testing has been in short supply in the U.S., it's possible that the company will be able to expand its customer base by getting people in the door with its COVID-19 tests and then cross-selling other tests afterward.

Last year, Everlywell raised around $50 million from investors, and it may need to raise more if it wants to continue to grow. Everlywell isn't profitable yet, but its leadership expects to be profitable within two years. For now, the company is working hard to produce and ship as many of its COVID-19 tests as possible.

Link:
Everything You Need to Know About At-Home Testing Start-Ups 23andMe, Ancestry, and Everlywell - The Motley Fool

Recommendation and review posted by Bethany Smith

Newborn and Prenatal Genetic Testing Market Size, Growth Opportunities, Trends by Manufacturers, Regions, Application & Forecast to 2025 – Cole of…

The latest research report on the Newborn and Prenatal Genetic Testing market is an in-depth examination of this business sphere and is inclusive of information pertaining to vital parameters of the industry. The report provides details about the prevailing market trends, market share, industry size, current renumeration, periodic deliverables, and profits projections over the forecast timeframe.

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An elaborate documentation of the Newborn and Prenatal Genetic Testing market performance during the analysis period is entailed in the report. Insights regarding the driving factors which will influence the market dynamics, alongside the growth pattern followed by the industry over the forecast period are presented. The report further focusses on analyzing the challenges existing in the market and growth prospects which define the business vertical over the forthcoming years.

Key highlights of the Newborn and Prenatal Genetic Testing market report:

Revealing the geographical landscape of the Newborn and Prenatal Genetic Testing market:

Summary of regional analysis presented in the Newborn and Prenatal Genetic Testing market report:

An exhaustive survey of Newborn and Prenatal Genetic Testing market with respect to product type and application scope:

Product scope:

Product types: PCR, FISH, aCGH, NIPT and MSS

Major pointers mentioned in the report:

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Application scope:

Application segmentation: Hospital, Clinic and Others

Insights entailed in the report:

Other takeaways from the Newborn and Prenatal Genetic Testing market report:

Elucidating details about the competitive topography of the Newborn and Prenatal Genetic Testing market:

Prominent players of the industry: Perkin Elmer, CapitalBio MedLab, Verinata Health, Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Sequenom, Inc., Ariosa Diagnostics, Natera, Inc., BGI, Illumina and Inc

Key parameters included in the report which define the competitive landscape:

The Newborn and Prenatal Genetic Testing market report also emphasizes on major industry aspects like market concentration ratio.

For More Details On this Report:https://www.marketstudyreport.com/reports/global-newborn-and-prenatal-genetic-testing-market-growth-status-and-outlook-2020-2025

Some of the Major Highlights of TOC covers:

Newborn and Prenatal Genetic Testing Regional Market Analysis

Newborn and Prenatal Genetic Testing Segment Market Analysis (by Type)

Newborn and Prenatal Genetic Testing Segment Market Analysis (by Application)

Newborn and Prenatal Genetic Testing Major Manufacturers Analysis

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Newborn and Prenatal Genetic Testing Market Size, Growth Opportunities, Trends by Manufacturers, Regions, Application & Forecast to 2025 - Cole of...

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Study finds genetic factors that make some more susceptible to Covid-19 – Health24

Another day, and another new study shining more light on the complexities of the coronavirus.

A group of European researchers, led by the University of Kiel's professor of molecular medicine Andre Franke, publishedtheir findings regarding a link between our genes and severe respiratory failure among Covid-19 patients inThe New England Journal of Medicine.

The massive genome-wide study was conducted on 1 980 patients from hospitals in Italy and Spain the European epicentres of the disease early in the year controlled against participants without coronavirus, or those who had no or mild Covid-19 symptoms.

It also included some participants from Norway and Germany, where the coronavirus had a much less devastating effect on the population.

READ:Leave your sunglasses at home if you're venturing out during the pandemic

Two genetic factors were found to influence the severity of Covid-19-induced respiratory failure and the need to be placed on ventilators namely clusters found in the 3p21.31 and 9q34.2 chromosomes.

One of the risk alleles is also associated with the ABO-blood groups. Those with blood type A were 45% more likely to develop the disease, while O has some protective effect that makes O types only 65% as likely to the get it compared to other blood groups.

A similar finding was shared by US private genetic testing company 23andMe. Their initial findings in an ongoing study showed that type O blood tends to be 9 to 18% less likely to test positive for Covid-19. However, they did not find one blood type to be more susceptible than any other. Another study from China also found that blood type A seemed more susceptible to the coronavirus.

But when it comes to the HLA genes that monitor our immune system, the researchers found no discernible link with Covid-19.

ALSO READ:One blood type seems to be more resistant against Covid-19

This European study also confirmed that their findings are backed up by the Covid-19 Host Genetics Initiative a consortium of the world's leading genetics scientists who share information that could help better understand the coronavirus threat.

However, former president of the American Society of Haematology Dr Roy Silverstein, told CNNthese results don't mean much to the general public, where this kind of genetic variance in a population isn't that significant.

For researchers though, this could be valuable information for developing treatment and vaccines against the coronavirus.

Recently, researchers found a breakthrough Covid-19 treatment using the steroid dexamethasone that reduces mortality. And regarding the rush for a vaccine, there are currently 100 vaccines in development, with eight having reached human trials.

ALSO READ:Are people with blood type A more vulnerable to contracting the new coronavirus

Image credit: Pixabay

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Study finds genetic factors that make some more susceptible to Covid-19 - Health24

Recommendation and review posted by Bethany Smith

Direct to Consumer (DTC) Genetic Testing Market Analysis, Evolving Opportunities, Industry Trends, Business Growth, Revenue And Forecast upto 2025 -…

Direct to Consumer (DTC) Genetic Testing Market Size was valued around USD 800 million in 2018 and is expected to witness lucrative growth from 2019 to 2025.

Rising adoption of genetic tests in various applications including cancer and various genetic disorders will augment the growth of direct to consumer genetic testing market over the forecast period. Currently developed DTC genetic tests allows customer to recognize chance of acquiring a genetic disease. Thus, growing adoption of DTC genetic testing for premature disease detection and identification of genetic diseases will boost the market growth over forecast timeline. However, the genetic tests are costly which may restrict the genetic testing market over forecast period.

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On the basis of test type the market is segregated into predictive testing, carrier testing, Ancestry & relationship testing, nutrigenomic testing and others. Predictive testing has potential to identify complicated disease which might be associated with the patient in future. Thus predictive testing can help in identifying the diseases ahead of time and suggest personalized medicine which aids to segmental growth of predictive testing market over the future.

Genetic testing market by technology is further divided into Targeted Analysis, Single Nucleotide Polymorphism (SNP) Chips, Whole Genome Sequencing (WGS). Targeted analysis is used to determine the defect in genes that are responsible for a particular disease. Targeted genotyping can precisely determine a persons genetic pool that encodes vital information regarding various disorders. Targeted analysis is less costly compared to rest of the test which will drive the adoption rate of this segment.

North America is anticipated to account for the largest share of the Global Genetic Testing Market. Increasing innovative technologies in genetic tests coupled with rising adoption of these tests will augment the growth of the market. Asia-Pacific is expected to show rapid growth in coming years. Increasing prevalence of chronic diseases will boost the APAC genetic testing market in forecast period.

By Test type

By Application

By Region

Company Coverage

Questions addressed in the report

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In this report, we had discussed the market situation of Direct to Consume Genetic Testing. As we know the world is going to be tech savvy, the demand of trending products and technologies is also increasing. This report can help to understand the business growth in the Direct to Consume Genetic Testing and new opportunities at new places.

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Blood Type and COVID-19 Risk – Everyday Health

One of the goals of COVID-19 research is understanding why some people develop mild or moderate cases while others experience life-threatening illness. Researchers have made progress in understanding some of the factors that make a difference, including obesity and underlying health conditions like diabetes and heart disease.

Recently, an ongoing study by European scientists has suggested one more potential factor to consider: blood type. Preliminary results of this investigation (which have not yet been peer reviewed) were shared on June 2 on the preprint service MedRxiv.

The researchers scrutinized blood samples from 1,610 hospitalized patients in Italy and Spain with the disease, as well as a 2,205 healthy people in a control group. Their analysis identified variations at two distinct areas on the genome (the complete set of human DNA, including all genes) that were associated with greater risk for severe reactions toSARS-CoV-2, the virus that causes COVID-19, including respiratory failure.

One of these areas on the genome is related to blood types. The researchers found that type A blood was associated with a 50 percent increase in risk that a patient would become extremely ill with COVID-19 and need supplemental oxygen or a ventilator.

This conclusion supports findings from early research done in China, which appeared March 27 in MedRxiv. This gave the researchers more confidence in the associations, says study coauthor Andre Franke, PhD, professor of molecular medicine at the Institute of Clinical Molecular Biology at University Hospital Schleswig-Holstein in Kiel, Germany.

Researchers on another ongoing study, by genetic testing firm 23andMe, released preliminary data on June 8 suggesting that type O blood is protective against COVID-19. The researchers found that people with type O blood are between 9 and 18 percent less likely to test positive for COVID-19 than other blood types.

The 23andMe study is still recruiting subjects, but already has 750,000 participants and is likely to come out with more data regarding genetic associations and COVID-19.

RELATED: The New Normal: What We Know About the Coronavirus So Far and How We Got Here

Dr. Franke hopes to build on the findings about type A blood withmore targeted research, he says, especially because there are 36 known human blood groups. In addition to the four main types A, B, AB, and O there is also a deeper classification system that includes different combinations of antigens (molecules on the surface of every red blood cell) and other substances.

There are other types of diseases where blood types and blood groups affect a persons susceptibility. For example, people who lack a specific type of antigen, called a Duffy antigen, have a higher resistance to malaria.

In terms of why a variant like the gene related to blood type would have significance for COVID-19, Franke says there are three possible hypotheses.

One is that the genetic variant itself contributes to the so-called cytokine storm, in which a persons immune system goes into overdrive in response to the novel coronavirus threat, releasing large amounts of pro-inflammatory substances called cytokines. An excess of cytokines can damage healthy tissues.

The second hypothesis is that the genetic variant causes more coagulation (blood clotting) in response to the coronavirus an already observed result of disease progression.

The third theory is that both of these reactions are occurring simultaneously.

There may be other issues at play here, but given the way we know COVID-19 works, these seem the most likely reasons, Franke says. Next steps are to dig deeper into the blood groups system and see if we can pinpoint actual disease causes.

RELATED: What People With Heart Disease Need to Know About COVID-19

What should you do in response to these studies, considering you can't change your blood type? Nothing yet. Theres no need to get to a doctor if youre type A, and on the flip side, theres no reason to relax your precautions against coronavirus transmission like social distancing and hand-washing if youre type O.

Keep in mind these are preliminary results and more research needs to be done to understand how genetic variations truly affect COVID-19.

More than anything, its a nod toward how much we have left to learn about the way this virus operates, and how genetic variants may affect why some people end up in the ICU and others have milder symptoms or even none at all, says Priya Duggal, PhD, director of the genetic epidemiology program at Johns Hopkins Bloomberg School of Public Health in Baltimore.

If we can find genes that may explain some of the risk or protection from this infection, it will give us insight into the mechanism of disease, she says.

If genetics studies help us better understand how COVID-19 affects the body, they may eventually help lead to treatments.

This genetic study is hopefully the first of many that will help us to elucidate disease mechanism, susceptibility to infection, and maybe even antibody response, says Dr. Duggal. That could provide potential targets for therapeutics. We have a lot to learn from this point, but were gaining more insight with every study.

Continued here:
Blood Type and COVID-19 Risk - Everyday Health

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Direct-To-Consumer (DTC) Genetic Testing Market Key Players, SWOT Analysis, Dynamics, Drivers, Key Indicators and Forecast to 2026 – Owned

New Jersey, United States,- A new study was presented by Verified Market Research offering a complete analysis of the Direct-To-Consumer (DTC) Genetic Testing Market where the user can benefit from the complete market research report with all the useful information required on this market. This is a final report, covering the current impact of COVID-19 on the market. The coronavirus pandemic (COVID-19) has affected all aspects of life around the world. This has resulted in several changes in market conditions. The rapidly changing market scenario and the initial and future impact assessment are addressed in the report. The report examines all major aspects of the market with expert opinion on the current state of the market as well as historical data. This market report is a detailed study of growth, investment opportunities, market statistics, analysis of growing competition, key players, industry facts, important figures, sales, prices, revenues, gross margins, market shares, business strategies, main regions, demand and developments.

The Direct-To-Consumer (DTC) Genetic Testing Market Report provides a detailed analysis of the global market size, regional and national market size, segment growth, market share, competitive landscape, sales analysis, the impact of players in national and global markets, value chain optimization, business regulations, recent developments, opportunity analysis, strategic analysis of market growth, product launches and technological innovations.

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Major Players Covered in this Report are:

Direct-To-Consumer (DTC) Genetic Testing Market Segmentation

This market has been divided into types, applications and regions. The growth of each segment provides a precise calculation and forecast of sales by type and application, in terms of volume and value for the period between 2020 and 2026. This analysis can help you develop your business by targeting qualified niche markets. . Market share data are available at global and regional levels. The regions covered by the report are North America, Europe, Asia-Pacific, the Middle East and Africa and Latin America. Research analysts understand competitive forces and provide competitive analysis for each competitor separately.

By Types:

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By Applications:

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Direct-To-Consumer (DTC) Genetic Testing Market Regions and Countries Level Analysis

The regional analysis is a very complete part of this report. This segmentation highlights Direct-To-Consumer (DTC) Genetic Testing sales at regional and national level. These data provide a detailed and precise analysis of the volume by country and an analysis of the market size by region of the world market.

The report provides an in-depth assessment of growth and other aspects of the market in key countries such as the United States, Canada, Mexico, Germany, France, the United Kingdom, Russia, the Italy, China, Japan, South Korea, India, Australia, Brazil and Saudi Arabia. The competitive landscape chapter of the global market report provides key information about market players such as company overview, total (financial) revenue, market potential, global presence, sales Direct-To-Consumer (DTC) Genetic Testing and the income generated, market share, prices, production sites and facilities, products offered and strategies adopted. This study provides Direct-To-Consumer (DTC) Genetic Testing sales, revenues and market shares for each actor covered in this report for a period between 2016 and 2020.

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Table of Contents

1. Executive Summary2. Assumptions and Acronyms Used3. Research Methodology4. Market Overview5. Global Market Analysis and Forecast, by Types6. Global Market Analysis and Forecast, by Applications7. Global Market Analysis and Forecast, by Regions8. North America Market Analysis and Forecast9. Latin America Market Analysis and Forecast10. Europe Market Analysis and Forecast11. Asia Pacific Market Analysis and Forecast12. Middle East & Africa Market Analysis and Forecast13. Competition Landscape

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Direct-To-Consumer (DTC) Genetic Testing Market Key Players, SWOT Analysis, Dynamics, Drivers, Key Indicators and Forecast to 2026 - Owned

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The Future of Skin Care Hinges on Keeping Time With Your Complexions Natural Rhythm – Well+Good

Its a little before midnight as I write, and thats breaking this storys rules. As the science surrounding circadian rhythms and the skin continue to solidify, my teenage-night-owl trail of wee-hours inspiration could actively be throwing off my skin from functioning in its optimal state. Skin circadian rhythm is a concept that brands and derms are studying as custom skin cares next breakthrough hinges on teeny, tiny metabolites, which play into the skins ability to stay in sync with the rest of our systems.

The beauty of studying metabolomics is that it takes into account your genetics, your microbiome and your environment to give an overall image of whats happening specifically to your skin at any time, explains Nadine Pernodet, PhD, Vice President of Skin Biology and BioActives at Este Lauder. When launching Advanced Night Repair Synchronized Complex II ($72) two decades ago, the brand targeted initial findings that skin metabolites oscillated, following a circadian rhythm, and those oscillations grow weak and erratic with age, impeding repair. Today, with even more evidence that a steady rhythm is the mark of healthy cells, its worth figuring out how to keep the beat for the betterment of skin.

Today, with even more evidence that a steady rhythm is the mark of healthy cells, its worth figuring out how to keep the beat for the betterment of skin.

The skin is the bodys largest organand also the easiest organ to accessso it can provide a lot of direct information, explains New York City-based dermatologist Jessica Weiser, MD FAAD. One means of assessing the skins natural rhythms is through the use of metabolites. All of the bodys organs produce small compounds during their metabolic processesthese metabolites account for genetic differences, environmental variations, behavioral changes, age, UV exposure, and more, she says. An assistant clinical professor of Dermatology at Columbia University and founder of Weiser Skin MD, she is keenly aware that this metabolic fingerprint is a promising therapeutic tool.

These metabolites can be retrieved from the skin surface to demonstrate what is happening on a cellular level, and then used to help better target skin-care treatment in an effort to affect the skins natural activities, she explains. Metabolite samples, when taken repeatedly at various times of the day, show cycles of protection and repair, which help guide how to maximize the repair processes in damaged skin. According to Dr. Weiser, we arent yet taking full advantage of this information. In the future, the new normal may be tailoring product routines to personal rhythms. Until then, heres how to maximize what we know and hack your general skin beat.

Since optimal repair processes require optimal rest, theres a direct tie between abbreviated sleep schedules and accelerated skin aging. The most familiar circadian rhythm is the sleep-wake cycle, Dr. Weiser explains. Since sleep is partially regulated by melatonin levels which typically peak at night, exposure to light sourceslike this screenafter a certain point causes an abrupt decrease in melatonin levels.

Why does melatonin matter? Interestingly, melatonin has many other roles including hair growth, reduction of UV damage in skin cells, wound healing, and more, says Dr. Weiser. When we alter the bodys natural melatonin production, we equally diminish its ability to repair damage at night. Hum Nutrition Mighty Night ($40) blends sleep-supporting herbs, antioxidants, and hydrating ceramides into an evening supplement designed to enhance overnight cell renewal, while Milk Makeups Melatonin Overnight Serum ($36) blends topical melatonin with Persian Silk Tree extract and hyaluronic acid for a push-pop-sized stick of solid serum.

According to Dr. Weiser, catching adequate ZZZs should be a natural prescription from forward-thinking derms. As a result of lack of sleep, the quality of someones skin can deteriorate cosmetically and medically, reinforces dermatologist Robert Anolik, MD, of the Laser & Skin Surgery Center of New York. From a cosmetic perspective, the stressors can weaken the quality of collagen fibers and skin tones, leaving the skin with fine lines and enlarged pores.

Generally, daylight is the time to protect, darkness is the time to regenerate. The founders of The Route, which designed a 24-Hour Skin Rhythm approach to their Everything Day ($90) and Everything Night ($90) multitasking moisturizers say that skin is a nocturnal animal. When the sun is out, its closed off to intruders. At night, it works to replace water loss and shifts into repair mode.

The brands product duo uses the bodys circadian clock to target the delivery of ingredients at optimal times for skin cells unique shifts. And metabolites play a role here as well. Its important that products have the right concentration of daytime metabolites to help with neutralizing the negative environmental effects and nighttime metabolites to support skin renewal, says Anne Chapas, MD, a dermatological advisor to Noble Panacea who notes that these are universal concepts nonspecific to age or gender.

She touts the brands Absolute Intense Renewal Serum ($420) for its Organic Molecular Vessels delivery system. As OMVs travel through the skin once they are applied, each vessel is programmed to deliver an ingredient for absorption at the optimal moment with control over a course of the day or through the night. And in addition to ingredients like the activation enzyme teprenone, which aids in the stabilization of telomeres at the end of chromosomes to delay cellular degeneration (more on DNA to come), theres a constant focus to keep skin protected and better able to meet the outside world in defense mode.

Ultimately, the goal is to keep up cells ability to repair themselves and their DNA.One specific skin-care company looking to stimulate the DNA repair and protection process is Defenage, says Dr. Weiser, who notes that a combination of alpha and beta defensins, natural immune peptides found in products like Defenage 24/7 Barrier Balance Cream ($127), have been shown to activate a stem cell found in the hair follicle. This specific stem cell is considered the source of most new epidermal cells during acute wound healing, and the defensin-mediated stimulation helps to promote a wound healing-like response. Results range from increased epidermal thickness to reduced appearance of pores and even pigmentation.

In the hyper-prestige market, La Prairie just introduced Platinum Rare Cellular Night Elixir at a price point of $1,275. The four functions essential to the skins complete regeneration process are addressed: nutrition, respiration, detoxification and immunity, the brand shares of the first-of-its-kind recipe. The elixir boasts the highest concentration of La Prairies Exclusive Cellular Complex, which provides nutrients like amino acids, nucleotides, and sugars required to synthesize biomoleculeslike proteins and DNAessential to cellular structure. And while the steep price point might make the serum out of reach for many, the science driving the innovation will no doubt inform how we approach skin care in the years to come.

As Dr. Chapas mentions, skin dehydration is a factor in accelerated cell dysfunction. Aside from drinking sufficient H2O, there are topical measures that can be taken. To help prevent transepidermal water loss, Pause Well-Aging Collagen Boosting Moisturizer ($72) maintains moisture balance for both morning and night while simultaneously encouraging cell turnoverand though it launched as a solution to increase activity in menopausal cells, its hormone-free formula is safe for all skin types.

At night in particular, skin blood flow and temperature are higher, which causes permeability of the skin barrier and increases water loss and skin itch, Dr. Weiser points out. This explains, at least partially, why many eczema patients feel more itchy in the evening. It would make sense to encourage the use of topical moisturizers or anti-inflammatory products at night. Tower 28 SOS Daily Rescue Facial Spray ($28) not only received the National Eczema Associations Seal of Acceptance, its rich in hypochlorous acid that triggers an immune boost in skin and helps fight inflammationanother rhythm disruptor.

Not only do we have a global body clock, but almost all of our cells have their own clocks, says Ben Van Handel, PhD, co-founder of Heraux and stem cell biologist at the University of Southern California. In an ideal world, these are keeping the same time. However, inflammation can influence crosstalk between these clocks, causing them to fall out of sync. (Think of a piece of spoiled fruit in a bowl encouraging other fruits to go bad sooner.)

These interruptions are bad news, as they can cause the production of more pro-inflammatory molecules, which further speeds up the biological clock in our skin in a feed-forward loop, explains Dr. Van Handelof of how this cyclical relationship between inflammation and aging led to the term inflammaging. Heraux Molecular Anti-Inflammaging Serum ($250) utilizes a proprietary biomimetic lipid HX-1, which boasts over a decade of research and 18 patents.

Designed to shield skin stem cells from the stress factors that drive inflammation, Dr. Van Handel explains that this protective effect allows skin stem cells, and their clocks, to function better and maintain sync with the rest of the body. Internally, a dose of Omega 3slike the vegan version found Athena Club Daily Multi ($28)have been shown to further support reduced inflammation levels in skin.

To back up the practice of using daytime UV protection and nighttime reparative topicals, Dr. Weiser points to a study that showed sun damage persisting for three hours after exposure actually occurred. When we think of this in terms of treatment options, it is possible that early use of potent antioxidants could stop this prolonged damage and thereby reduce the increased risk of skin cancer development, she shares.

Dr. Loretta Urban Antioxidant Sunscreen SPF 40 ($50) provides antioxidant protection from free radical damage caused by pollution and UV radiation while harnessing Indian ginseng extract as a way to protect skin from HEV light emitted from the sun and electronic devices. Adding a few drops of RVive Defensif Environmental Antioxidant Booster ($175) to your moisturizer levels-up antioxidants and ingredients known to protect from smoke, blue light wavelengths and environmental aggressors that stress skin from morning to night.

And so, until the ability to test your personal cell rhythm exists, the complexities of skins rhythm net out to a fairly simply takeaway that we can implement starting today and forevermore: Protect, feed, and rest your skin as needed, when needed, and itll do its best to keep working its natural biomimetic magic.

Our editors independently select these products. Making a purchase through our links may earn Well+Good a commission.

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The Future of Skin Care Hinges on Keeping Time With Your Complexions Natural Rhythm - Well+Good

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Global Amniotic Fluid Stem Cell Therapy Market Revenue to Record Stable Growth Through 2026 – Cole of Duty

Stem cells are biological cells which have the ability to distinguish into specialized cells, which are capable of cell division through mitosis. Amniotic fluid stem cells are a collective mixture of stem cells obtained from amniotic tissues and fluid. Amniotic fluid is clear, slightly yellowish liquid which surrounds the fetus during pregnancy and is discarded as medical waste during caesarean section deliveries. Amniotic fluid is a source of valuable biological material which includes stem cells which can be potentially used in cell therapy and regenerative therapies. Amniotic fluid stem cells can be developed into a different type of tissues such as cartilage, skin, cardiac nerves, bone, and muscles. Amniotic fluid stem cells are able to find the damaged joint caused by rheumatoid arthritis and differentiate tissues which are damaged. Medical conditions where no drug is able to lessen the symptoms and begin the healing process are the major target for amniotic fluid stem cell therapy. Amniotic fluid stem cells therapy is a solution to those patients who do not want to undergo surgery. Amniotic fluid has a high concentration of stem cells, cytokines, proteins and other important components. Amniotic fluid stem cell therapy is safe and effective treatment which contain growth factor helps to stimulate tissue growth, naturally reduce inflammation. Amniotic fluid also contains hyaluronic acid which acts as a lubricant and promotes cartilage growth.

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With increasing technological advancement in the healthcare, amniotic fluid stem cell therapy has more advantage over the other therapy. Amniotic fluid stem cell therapy eliminates the chances of surgery and organs are regenerated, without causing any damage. These are some of the factors driving the growth of amniotic fluid stem cell therapy market over the forecast period. Increasing prevalence of chronic diseases which can be treated with the amniotic fluid stem cell therapy propel the market growth for amniotic fluid stem cell therapy, globally. Increasing funding by the government in research and development of stem cell therapy may drive the amniotic fluid stem cell therapy market growth. But, high procedure cost, difficulties in collecting the amniotic fluid and lack of reimbursement policies hinder the growth of amniotic fluid stem cell therapy market.

The global amniotic fluid stem cell therapy market is segmented on basis of treatment, application, end user and geography:

Rapid technological advancement in healthcare, and favorable results of the amniotic fluid stem cells therapy will increase the market for amniotic fluid stem cell therapy over the forecast period. Increasing public-private investment for stem cells in managing disease and improving healthcare infrastructure are expected to propel the growth of the amniotic fluid stem cell therapy market.

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Some of the key players operating in global amniotic fluid stem cell therapy market are Stem Shot, Provia Laboratories LLC, Thermo Fisher Scientific Inc. Mesoblast Ltd., Roslin Cells, Regeneus Ltd. etc. among others.

However, on the basis of geography, global Amniotic Fluid Stem Cell Therapy Market is segmented into six key regionsviz. North America, Latin America, Europe, Asia Pacific Excluding China, China and Middle East & Africa. North America captured the largest shares in global Amniotic Fluid Stem Cell Therapy Market and is projected to continue over the forecast period owing to technological advancement in the healthcare and growing awareness among the population towards the new research and development in the stem cell therapy. Europe is expected to account for the second largest revenue share in the amniotic fluid stem cell therapy market. The Asia Pacific is anticipated to have rapid growth in near future owing to increasing healthcare set up and improving healthcare expenditure. Latin America and the Middle East and Africa account for slow growth in the market of amniotic fluid stem cell therapy due to lack of medical facilities and technical knowledge.

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Global Amniotic Fluid Stem Cell Therapy Market Revenue to Record Stable Growth Through 2026 - Cole of Duty

Recommendation and review posted by Bethany Smith

Serena Williams reveals her skincare regimen – HOLA USA

Serena Williams is an athlete with a busy schedule who has early morning activities. However, she makes sure to go live on Instagram for her Serena Saturdays series where she talks about fashion, beauty and relationships. While Serenas schedule is full of training, the athlete always finds time to practice wellness and is dedicated to show her daughter, Olympia Ohanian how to take care of her skin. In a recent live video, the 38-year-old tennis player revealed her go-to moisturizer and daily skincare practice. One of her most essential beauty product is the eye serum. Eye cream doesnt work unless you put some serum on before, shared Serena.

Though Serena forgot to add serum on her face, she confesses this is an essential step during her skincare regimen. The professional athlete swears by Trilogy Vitamin C Moisturising Lotion which features antioxidants that helps skin prevent damage and recover from free radical exposure. In addition, this moisturizer is known for its radiance-boosting properties which helps the complexion look fresher and brighter. Trilogys formula includes daisy extract and mandarin oil with extra brightening properties such as certified organic Rosehip Seed Oil to help the skin hydrate, replenish and strengthen skins moisture barrier. Aside from using a vegan product, Serena applies Neocutis restorative eye cream after applying eye serum and uses it on her entire face whenever her skin feels extra dry.

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Serena Williams reveals her skincare regimen - HOLA USA

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Rapid Unit Sales of Oncology Drugs to Account for Incremental Revenues in the Global Market – Cole of Duty

Oncology is a branch of study and treatment of cancer. Cancer is disease in which abnormal cells grow and divide without control. Oncology drugs help in diagnosis cancer. Some of the causes of cancer are tobacco and smoking, viral infections, genetic causes, carcinogens, bacterial infections, physical activities, eating habits and age. Various types of cancer that can be treated by oncology drugs are blood cancer, endocrine cancer, lung cancer, bone cancer, skin cancer, genitourinary cancer, gastrointestinal cancer, breast cancer, eye cancer, head and neck cancers and gynaecologic cancer. On the basis of treatment, oncology drugs market can be segmented into chemotherapy, immunotherapy, surgery, radiation therapy, stem cell transplant, hormone therapy and others.

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North America, followed by Europe, has the largest market for oncology drugs due to new drug development, government initiatives and developed healthcare infrastructure in this region. Asia is expected to show high growth rate in the oncology drugs market in next few years due to increasing incidence of cancer cases, rise in the use of tobacco products and growth in aging population in the region.

Technological advancement, increasing incidence of various type of cancers, rise in need for R&D activities in cancer and growing concerns over high death rates due to cancer are driving the market for oncology drugs. In addition, introduction of new drugs and therapies for cancer and government support to improve healthcare condition are expected to drive the market for oncology drugs. However, high cost of cancer treatments, strict government regulations, huge investment involvement in the development and clinical trials of the therapies and side effects of cancer treatments are some of the major factors restraining the growth for global oncology drugs market.

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Growing demographics and economies in the developing countries such as China and India are expected to offer good opportunities in oncology drugs market in Asia. In addition, new innovations in cancer drugs and therapies and rise in awareness about the new drugs and therapies available in the market are expected to offer new opportunities for global oncology drugs market. Personalized medicines, increasing number of mergers and acquisitions, new product launches and rise in number of collaborations and partnerships are some of the trends that have been observed in global oncology drugs market.

Some of the major companies operating in the global oncology drugs market are Amgen, Bayer Healthcare AG, CELGENE CORPORATION, GlaxoSmithKline, ARIAD Pharmaceuticals, Inc., Eli Lilly and Company, Novartis, Hoffmann-La Roche Ltd., AstraZeneca, Boehringer Ingelheim GmbH, Pfizer and Teva Pharmaceuticals Industries.

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Rapid Unit Sales of Oncology Drugs to Account for Incremental Revenues in the Global Market - Cole of Duty

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The UN is going to consider the Vitaspace Declaration on Radical Life Extension – PR Web

ST. PETERSBURG, Russia (PRWEB) June 18, 2020

The Vitaspace project was founded by the famous Russian entrepreneur Andrey Fomenko in 2018. Its goal is to join forces to radically prolong life and find a way (medicine or technology) that will help to preserve youth, restore health, and significantly postpone the aging period. This project was supported by various scientists from all over the world, doctors, and all people who care.

The other day, Vitaspace members published a petition at http://www.change.org calling for the acception of their Declaration on Radical Life Extension to ensure that all people and nations respect its foundations and promote its initiatives. The founders of Vitaspace have also sent an official letter to the UN to consider and support this document.

The Declaration on Radical Extension of Life consists of two parts: the first - Human Rights - proclaims the right to a long, healthy life as the most important value to be respected and protected; the second - Activities - is a practical strategy to overcome the challenges to a long, active life.

As Vitaspace citizens believe, radical prolongation of life and youth is a real opportunity, not an unattainable goal. In their opinion, people and governments of all countries should unite in the fight against the two worst enemies of humanity - aging and death.

Vitaspace is looking forward to the support of all interested people in the distribution of the Declaration, as well as the participation of the UN in the implementation of its ideas.

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The 10 Best Zinc Supplements of 2020 – Healthline

We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. Heres our process.

Zinc is an essential micronutrient thats needed for numerous functions in your body. Its also important for a strong immune system and helps keep your skin, eyes, and heart healthy (1, 2, 3, 4).

While there are many food sources of zinc, including meat and shellfish, some people may be at a higher risk of not getting enough zinc in their diets (5).

For example, those with inadequate access to food, pregnant or breastfeeding women, vegetarians and vegans, people with gastrointestinal disorders, and individuals taking certain medications like diuretics and anticonvulsants may benefit from a zinc supplement (5, 6, 7).

The zinc supplements in this review are all manufactured by reputable companies that follow Good Manufacturing Processes (GMP), use high quality ingredients, and test for purity and quality.

Here are the 10 best zinc supplements to help you meet your nutritional needs.

Price: $

Thorne Research is a supplement company that has its own dedicated scientists, labs, and research facilities for nutrition supplements.

All of their products are made in a lab that meets regulations and standards set by NSF International and the Therapeutic Goods Administration (TGA), which is a regulatory body in Australia thats responsible for assessing the safety of supplements.

Furthermore, their products are NSF Certified for Sport. This means that the products are tested to ensure the absence of more than 200 substances banned by many major athletic organizations.

Thorne Researchs Zinc Picolinate is one of the best zinc supplements on the market due to the companys high quality standards, purity of ingredients, and form of zinc used.

Older research suggests that zinc picolinate may be one of the easiest forms of zinc for your body to digest and absorb (8).

One tablet of this supplement provides 30 mg of zinc picolinate. For best results take one tablet per day, or as recommended by your healthcare provider.

Shop for Thorne Researchs Zinc Picolinate online.

Price: $

Chelated zinc is a type of zinc supplement that uses a chelating agent to help your body absorb zinc more easily.

While there are several chelated zinc supplements on the market, one of the best options is NOW Foods Zinc Glycinate softgels.

Each softgel contains 30 mg of zinc glycinate a form of zinc that human and animal studies suggest may be better absorbed than other types of zinc. (9, 10).

All NOW Foods supplements are certified by Underwriters Laboratories and follow GMP to ensure the quality and accuracy of their products. Additionally, these supplements tend to be more affordable than many other high quality brands.

Shop for NOW Foods Zinc Glycinate Softgels online.

Natures Way produces high quality supplements that are more affordable than many other brands on the market.

All of their supplements are manufactured in facilities that NSF has certified as meeting GMP requirements, which include a set of guidelines to ensure accuracy, quality, and purity of products.

In addition, their products are non-GMO, organic, and TRU-ID certified. TRU-ID certification is a relatively new independent testing program that uses DNA to verify the authenticity of ingredients in supplements.

For zinc products, Natures Way offers zinc chelate capsules and zinc lozenges, both of which are budget-friendly.

Price: $

These zinc chelate capsules are gluten-free and provide 30 mg per capsule.

For best results, adults and adolescents over the age of 14 should take one capsule daily with food, or as recommended by your healthcare provider.

Shop for Natures Way Zinc Chelate Tablets online.

200

Price: $

For those interested in lozenges, each of Natures Ways Zinc Lozenges provides 23 mg of zinc, as well as 100 mg of vitamin C and 20 mg of Echinacea purpurea.

Although the label suggests that adults can take up to 6 lozenges per day, this would push your daily zinc intake way over the suggested 40-mg tolerable upper intake level (UL) set for zinc (11).

Taking too much zinc can have adverse effects on your health and may interfere with the absorption of other nutrients. Its important that you check with your healthcare provider before taking high dose zinc supplements to ensure safety.

Shop for Natures Way Zinc Lozenges online.

Price: $$

While its not always obvious, some supplements can contain animal-derived ingredients, making the product unsuitable for vegans.

Some commonly used ingredients that arent vegan-friendly include digestive enzymes like lipase, caprylic acid from milk, gelatin, and magnesium stearate, which is often pork-derived.

Garden of Life is a whole-foods-based supplement brand with products that are certified organic and non-GMO verified.

Their Vitamin Code Raw Zinc is a good option for vegans, as its third-party tested to ensure the product is vegan, as well as gluten-free.

In addition to providing 30 mg of plant-based zinc, each serving also contains vitamin C, a raw organic fruit and vegetable blend, and live probiotics and enzymes to support healthy digestion.

Its recommended that adults take one serving of 2 capsules per day with or without meals. For those who have difficulty swallowing pills, the capsules can also be opened to pour the contents into a glass of water or other beverage.

Shop for Garden of Life Vitamin Code Raw Zinc online.

For those who have difficulty swallowing pills, liquid forms of zinc may be better tolerated.

Price: $$$

Metagenics is a supplement company devoted to transparency and quality. Each ingredient and supplement batch is tested for quality, and you can even access a detailed testing report for the specific supplement youre looking to buy.

As part of their quality assurance, all Metagenics supplements are USP-verified and meet NSF and Therapeutic Goods Administration (TGA) safety and quality regulations.

Their Zinc Drink liquid supplement contains only water and 15 mg of zinc sulfate per serving, making it free of any additives and preservatives.

For best results, take 1 teaspoon (5 mL) per day of the Zinc Drink between meals. While you can take the supplement on its own, it can also be mixed into a glass of water.

Shop for Metagenics Zinc Drink online.

Price: $$$

Peak Performance supplements are made in the United States and developed for busy athletes and professionals.

In addition to being free of major allergens, including soy, dairy, wheat, egg, shellfish, and peanuts, Peak Performances Raw Ionic Liquid Zinc is also vegan-friendly.

By running zinc through a high pressure, low heat process, the zinc particles in this liquid supplement are very small in size, which may make it easier for your body to absorb.

One full dropper provides 15 mg of zinc sulfate a form of zinc that has been shown to help prevent zinc deficiency, reduce symptoms of severe acne, and possibly help slow the progression of age-related macular degeneration (AMD) (6, 12).

All Peak Performance supplements undergo third-party testing for quality and accuracy. Theyre also manufactured following Food and Drug Administration (FDA), GMP, and NSF regulations and standards.

Adults should take one full dropper (1 mL) once a day on an empty stomach, or use as directed by your healthcare provider.

Shop for Peak Performance Raw Ionic Liquid Zinc online.

Price: $$

Zinc lozenges are small tablets that are meant to dissolve slowly in your mouth. Theyre typically taken for short periods to help reduce the symptoms and duration of the common cold.

In fact, one review found that consuming a dose of 8092 mg of zinc from zinc lozenges per day helped reduce the duration of the common cold by up to 33% (13).

Life Extension has been making high quality supplements for over 40 years.

In addition to being manufactured in an NSF-registered GMP facility, each product has a certificate of analysis thats available for consumers to confirm the quality and accuracy of a specific product.

Life Extensions Enhanced Zinc Lozenges contain 18.75 mg of zinc acetate a form of zinc that has been shown to shorten the duration of colds by up to 40% (13).

Adults can take 1 lozenge every 2 hours up to 8 times a day. However, its not recommended to consume these lozenges for more than 3 days in a row. Also, note that taking this supplement 8 times per day will greatly exceed the daily UL of 40 mg.

Shop for Life Extension Enhanced Zinc Lozenges online.

Price: $$

If youre looking for an organic zinc supplement, NutriGolds Zinc Gold is one of the best options out there.

Each capsule contains 15 mg of whole-foods-based zinc thats derived from an organic sprouted blend, which the supplement claims may be gentler on your stomach.

Additionally, NutritGolds supplements are certified organic by SCS Global Services, an official partner of the United States Department of Agriculture (USDA) that sets sustainability, quality, and organic standards.

Each product is also third-party tested, as well as non-GMO and vegan certified.

Adults should take 1 capsule daily, or as directed by your healthcare provider.

Shop for NutriGold Zinc Gold online.

Price: $

If youre looking for a gluten-free zinc supplement, Pure Encapsulations is one of your best options.

The products are not only made in a facility thats NSF-registered GMP but also certified gluten-free by the Gluten-Free Certification Organization (GFCO). Plus, they contain zinc picolinate to optimize digestion and absorption.

For optimal results, its recommended to take one 30-mg zinc picolinate capsule daily with food.

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When choosing a zinc supplement, its important to consider the type of zinc, dosage, and supplement form.

There are several types of zinc supplements. Some, such as zinc picolinate, may be better absorbed, while zinc acetate may be more effective at shortening the duration of the common cold (8, 13).

As for dosage, the recommended daily dosage for adults is typically 1530 mg of elemental zinc per day. Elemental zinc is generally the amount listed on the label of your supplement (5, 6).

Due to potential side effects of excess zinc, its best not to exceed 40 mg per day unless under medical supervision (11).

Taking too much zinc can cause adverse side effects, such as decreased immune function, low copper levels, and reduced HDL (good) cholesterol levels.

Regarding the form, zinc supplements are available as capsules, lozenges, and liquids. For those who are unable or prefer not to swallow pills, liquid forms are likely a better option.

Before buying any supplement, its important to research high quality, trustworthy brands to ensure both safety and accuracy.

Look for supplements that are produced by reputable manufactures and free of large amounts of added ingredients like fillers, additives, and preservatives.

A good way to ensure the quality of a product is to look for ones that have been certified by a third-party company, such as NSF International or Underwriters Labs.

Zinc is an essential nutrient that you need to get enough of in your diet. However, as not everyone is able to meet their need through foods alone, supplements can help reduce the risk of a zinc deficiency.

Of course, not all supplements are created equal. Its important to look for high quality products that have been tested to ensure quality and accuracy.

If youre concerned about your zinc intake, its worth speaking with your healthcare provider to see if a zinc supplement is a good option, as well as to determine an optimal dose.

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The 10 Best Zinc Supplements of 2020 - Healthline

Recommendation and review posted by Bethany Smith

The line between ‘elective’ and ‘essential’ is often hazy – Bryan-College Station Eagle

Late February was the last time I saw Mr. Fields, a man in his sixties with debilitating nausea, bloating and regurgitation. (To protect his privacy, I have changed his name and other identifying details.) His symptoms made it difficult for him to eat, and he was losing weight visibly from one clinic visit to the next. His last upper endoscopy - a procedure to inspect the top of his gastrointestinal tract - was aborted because there was a pile of food sitting in his stomach, despite his having fasted since midnight the day before. We had discussed repeating the endoscopy after a prolonged liquid diet to determine what was holding up his digestion (a tumor, an ulcer, or a general sluggishness of the muscle) and to use this information to guide his treatment.

Then the pandemic hit, and priorities changed. On a Friday afternoon in mid-March, I was asked to cancel the bulk of the procedures I had scheduled for the following Monday. From higher up, we received instructions to review every patient's chart, to separate the emergent from the urgent from routine. Mr. Fields certainly wasn't the only one perched on a borderline - it's the nature of my gastroenterology practice, as it is for most diagnostic proceduralists, not to know what I'll find until I go looking. My colleagues and I turned to each other for guidance. How worried would you be about an 80-year-old with iron-deficiency anemia? How about a 40-year-old with rectal bleeding? A 20-year-old unable to swallow? There was no question that they merited procedures, but when? Could they stand to wait four weeks? Eight? Twelve?

What does "elective" mean, really? It's intuitive to think about illness as varying along a spectrum of urgency: On one end, a hangnail; on the other, a heart attack. The term also implies that treatment can also vary along a spectrum of need, from cosmetic surgery to cardiopulmonary resuscitation. Most of medicine sits in the middle, asking us to balance potential health benefits against potential costs, such as missed diagnoses, procedural complications or, more recently, a covid-19 infection after visiting a medical building.

While the country debates whether to prioritize reopening the economy or minimizing preventable deaths, we face our own complicated trade-offs within the practice of medicine. The pandemic logic of triage - a process, borrowed from wartime, of prioritizing sick individuals according to the severity of their prognosis - exerts novel pressure on a system not used to such resource scarcity. Individual clinicians are grappling with what is truly necessary and urgent.

During my first week back to work in the endoscopy suite last month, I had trouble convincing any of my originally scheduled patients to come in for their procedures.Their episodic abdominal pain, refractory heartburn, and unrelenting diarrhea had seemed pressing just a few months before, but now the threat of infection loomed larger. Alongside clinicians, patients make their own judgments about what constitutes essential health care - about how to value the reassurance of resolving old symptoms against the risk of getting sick with something new and even more uncertain.

The calculus quickly gets complicated. We have to weigh not only the patient's health but that of the physicians, nurses, technicians and custodians who keep a procedural space operational. Concerns about infection also ripple from patients and providers to all their family members who might be affected. The masks and gowns protecting one cohort of health care workers could always be set aside for a needier cohort later. And staff relieved of their nonessential duties in a procedural suite could theoretically be reassigned to other settings where they might be of greater service.

On the other side of the equation, there are certainly diseases that become more dangerous when left unattended. A few of my colleagues in other cities worry vocally about how many gastrointestinal malignancies they'll find once routine practice picks up again. Less vocally, they worry about the legal implications of not having made the diagnosis earlier, wondering if they'll be liable for not having pushed more procedures into hospital settings even as federal or professional society guidance and state executive orders limited elective procedures. The potential hazards of clinical lag time also hold true for other specialty areas - blurry vision can herald impending strokes, and unattended orthopedic injuries can settle into contractures. In the background is the unsettling awareness that interventions deemed essential in one state may be elective in the next, particularly for politically sensitive services like abortion.

The line dividing essential from elective care is always a subjective one, because risk-benefit calculations tend to shift over time. The past few months have occasioned especially dramatic fluidity, but larger-scale changes have also unfolded over the past several decades. In the 1960s, specialties began lobbying for new interventional environments like the ambulatory surgical center, while emergency rooms arose as distinct hospital spaces for managing acute concerns. Meanwhile, chronic disease prevalence and pharmaceutical incentives inspired increasing professional interest in the idea of risk states (like high cholesterol as a precondition for heart disease, or age and gender as preconditions for breast cancer), which in turn entrenched preventive maneuvers (from annual physicals to mammograms to a daily aspirin) as vital elements of routine care. The insurance industry overlaid these developments with thorny questions about medical necessity.

In a sense, it's been remarkable how successfully patients have avoided clinical settings in these first few months of the pandemic. Early anecdotal reporting noted surprising drops in hospital admissions for common medical emergencies like cardiovascular events, appendicitis and strangulated hernias, and international data have begun to confirm these trends. In the United States, emergency catheterization procedures for life-threatening heart attacks were down 38 percent in the early phase of covid-19, despite predictions that those events would be, if anything, more prevalent during a viral pandemic. Fewer cirrhosis patients are being admitted to Veterans Health Administration hospitals, according to a study recently published by my colleagues at the University of Pennsylvania, and those who are admitted have been, on average, measurably sicker than baseline.

Contemporary biomedicine certainly prioritizes procedures financially, but also emotionally and culturally. Objective observations gathered by diagnostic maneuvers like CT scans, tissue biopsies and cardiac catheterizations have become a linchpin of clinical certainty. They are vital to a confident diagnosis and treatment plan and, when edged with the promise of life extension, serve as a kind of salve for the threat of mortality. These assumptions are so foundational to modern medicine that it can be shocking to question their validity.

Well before covid-19, the writer Barbara Ehrenreich detailed her decision to turn away from screening tests like colonoscopies, contending that they delude us into approaching death as a problem to be solved while at the same time invading the body to the point of violation: "if mammography seems like a refined sort of sadism," she notes, "colonoscopies mimic an actual sexual assault." It's a provocative argument, easier to accept in the abstract than when I recall patients with cancers I've found on years-overdue colonoscopies. Our infrastructure of high-tech diagnostic intervention can seem particularly bloated in the context of a pandemic, but patients and clinicians alike are often deeply and justifiably invested in it.

Ultimately, clean distinctions between essential vs. elective care are rhetorically convenient but clinically reductive. Sacrifices are entailed on both sides, and the messy work of negotiating the pros and cons will persist as the pandemic recedes. The same might be said for all-or-nothing debates pitting human life against a solvent economy - a compelling thought exercise, but less relevant in practical terms. Accumulating job losses are leaving more and more people uninsured, for example, forcing them to continue deferring elective medical care once it picks up again. Progressive dreams of radical reform notwithstanding, the medical and financial priorities of our healthcare system are deeply enmeshed, and for now, grappling with either means grappling with both.

Every day provides new data, and with it another opportunity to reweigh our priorities. In Philadelphia, where I work, our projected peak was at the end of April, and the first surge of covid-19 cases appears to have crested. Stocks of personal protective equipment are no longer dangerously depleted, and opportunities exist for systematic testing. These developments will afford us more space to evaluate those uninfected patients with separate, slow-burning complaints.

I recently re-connected with Mr. Fields; I hope he doesn't hold this interruption of his care against me. I'm ready to pick up where we left off, but covid-19 has made it harder to pretend that medicine operates in a vacuum. I marvel at the confidence of our pre-pandemic therapeutic encounters, which so often left implicit all the indelicate questions of financial incentives, workers' well-being, and the capacity of medicine to harm as well as to heal. Once the crisis lifts, it's hard to imagine returning to such thoughtless certainty.

Ahuja is an assistant professor of clinical medicine in the division of gastroenterology and hepatology at the University of Pennsylvania.

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The line between 'elective' and 'essential' is often hazy - Bryan-College Station Eagle

Recommendation and review posted by Bethany Smith

Eye Health Supplements Market New Detailed Information: Market by Global Trends, Business Growth, and Forecasts 2026 – Flagler Times

The global Eye Health Supplements Market research report thoroughly explains each and every aspect related to the Eye Health Supplements Market, which facilitates the reports reader to study and evaluate the upcoming market trend and execute the analytical data to promote the business. The growth trend forecasted on account of thorough examination offers in-depth information regarding the global Eye Health Supplements Market. A pathway of development is offered by the market to the several connected networks of businesses under it, which include different firms, industries, organizations, vendors, distributors, and local manufacturers too. All the key Eye Health Supplements Market players compete with each other by offering better products and services at a reasonable price in order to grab significant share at the regional and global level market.

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Major Players Are:Bausch + Lomb, Vitabiotics Ltd., Valeant Pharmaceuticals International Inc., Life Extension, Pfizer Inc., OmniActive Health Technologies, Algatechnologies, Alliance Pharma, The Natures Bounty Co., Novartis AG, and Amway Corp.

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Various analytical tools such as SWOT, Feasibility analysis, Porters Five Forces analysis, Value Chain analysis, and Capacity utilization analysis are implemented while evaluating the Eye Health Supplements Market which certainly helps a reader to get a deeper perception of the market and its participants. Additionally, it covers a cardinal evaluation of market history, patterns, changing dynamics, market and manufacturing trends, demand and supply activities, and technological development.

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Eye Health Supplements Market New Detailed Information: Market by Global Trends, Business Growth, and Forecasts 2026 - Flagler Times

Recommendation and review posted by Bethany Smith

No fountain of youth: Just because theres a way to boost testosterone doesnt mean you should, experts warn – The Gardner News

Testosterone therapy ads promise to help aging men recapture their vitality, decrease body fat and enhance libido. But hormone treatments while medically necessary for some men arent meant to be a fountain of youth, and experts warn more research is needed to determine if such therapy could boost heart disease risks.

Testosterone levels naturally decline in most men as they age. This decline is generally mild, and symptoms often are nonspecific, such as low energy, reduced muscle mass and reduced vigor. Roughly 20% of men over the age of 60 have experienced a drop in testosterone levels, though this gradual decline can begin as early as the mid-30s.

While that can be frustrating, experts say its not a clinical indication of a need for testosterone therapy, nor is there any evidence that therapy is effective for treating those symptoms. The Food and Drug Administration has limited approval of testosterone therapy to the treatment of organic hypogonadism, a dramatic drop in testosterone caused by disease or injury of the hypothalamus, pituitary gland or the testes.

If testosterone therapy is used appropriately in men with organic hypogonadism, then there is no controversy, said Dr. Shehzad Basaria, associate director of Mens Health: Aging and Metabolism at Brigham and Womens Hospital in Boston. The condition causes specific symptoms such as decreased sexual desire, breast enlargement, testicular atrophy and hot flashes.

But in middle-aged and aging men who have a slightly lower testosterone level and nonspecific symptoms due to aging or obesity, testosterone therapy is not indicated. Similarly, testosterone is not a rejuvenation drug, said Basaria, an associate professor of medicine at Harvard Medical School. The majority of patients seen in our clinics have symptoms such as fatigue, weight gain, muscle loss or feeling sad. These symptoms are common and nonspecific, and testosterone therapy is generally not indicated in such clinical scenarios.

Over the past two decades, intense direct-to-consumer marketing of hormone therapy for aging men, much of it via television ads, has more than doubled its off-label use. Its a trend experts warn is medically unwarranted and potentially harmful.

The American College of Physicians, which issued new guidelines in January, recommends against prescribing testosterone therapy to boost energy, vitality or physical function, but supports its use for men experiencing sexual dysfunction. The recommendation calls for discussing potential benefits and risks with the patient and discontinuing treatment after one year if there is no improvement.

I think one of the biggest concerns about testosterone therapy is whether it is really needed, said Dr. Robert Eckel, professor of medicine and an endocrinologist at the University of Colorado School of Medicine in Aurora, Colorado. Erectile dysfunction is a common problem as men age, but there can be other reasons for this, such as vascular disease or nerve damage, which is more common in patients with diabetes. It is not necessarily an indication for treatment with testosterone therapy. The patient must be properly evaluated.

The FDA warns against prescribing testosterone therapy for age-related hormonal decreases or anything other than a medical diagnosis of hypogonadism. Since 2015, it has required testosterone product labels to warn of a possible increased risk of heart attacks and stroke.

But research about that association so far is unclear, Basaria said

Some studies have reported higher cardiovascular risk with testosterone use but there are an equal number of studies showing that it does not increase cardiovascular risk, he said. This discrepancy exists because no study published to date has been powered to assess cardiovascular events as the primary outcome.

Eckel, president of medicine and science for the American Diabetes Association and a past president of the American Heart Association, agreed. The cardiovascular disease outcome story is not convincing one way or another. I think to make a strong statement here would be a mistake.

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No fountain of youth: Just because theres a way to boost testosterone doesnt mean you should, experts warn - The Gardner News

Recommendation and review posted by Bethany Smith

Human Chorionic Gonadotropin (hCG) Market Insights on Growth Trends, Top Players, Types, Applications and Regional Analysis – Personal Injury Bureau…

Latest Research Report on Global Human Chorionic Gonadotropin (hCG) Market Forecast to 2027 Covid-19 Impact and Global Analysis by Technology (Natural Source Extraction, Recombinant Technology); Therapeutic Area (Female Infertility Treatment, Male Hypogonadism, Oligospermic Treatment, Others); End User (Fertility Clinics, Research Institutions, Others).The research report provides deep insights into the global market revenue, parent market trends, macro-economic indicators, and governing factors, along with market attractiveness per market segment. The report provides an overview of the growth rate of the Human Chorionic Gonadotropin (hCG) market during the forecast period, i.e., 20202027. Most importantly, the report further identifies the qualitative impact of various market factors on market segments and geographies. The research segments the market on the basis of product type, application, technology, and region. To offer more clarity regarding the industry, the report takes a closer look at the current status of various factors including but not limited to supply chain management, niche markets, distribution channel, trade, supply, and demand and production capability across different countries.

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Some of the key players profiled in the study are Merck & Co, Inc, Ferring B.V, Fresenius Kabi AG, Cigna, Sun Pharmaceutical Industries Ltd, Lee BioSolutions Inc, Sanzyme, Scrippslabs , Lupin AB, Prospec-Tany Technogene Ltd, etc.

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Human Chorionic Gonadotropin (hCG) Market Study: An Introduction to Fundamental Charting

Human chorionic gonadotropin also known as hCG. This hormone plays a different role in both male & female sexual development. In female, the hCG mostly used to identify defect and confirm pregnancy and it is made from placenta during pregnancy which nourishes the egg after it has been fertilize. In male, especially young boys it used to increase sperm count. The hCG is administrated in body through the injection under skin into muscle. The human chorionic gonadotropin level can be Identify with the help of blood and urine test.

The human chorionic gonadotropin (hCG) market is expected to grow during the forecast period due to changing life style and increase stress level in life which affects the fertility related disease, rising incidences of male hypogondism among the geriatric population are major key driving factors of the human chronic gonadotropin market. Raising the demands and availability of infertility treatment are likely to create growth opportunities during forecast period.

The report profiles the key players in the industry, along with a detailed analysis of their individual positions against the global landscape. The study conducts SWOT analysis to evaluate strengths and weaknesses of the key players in the Human Chorionic Gonadotropin (hCG) market. The researcher provides an extensive analysis of the Human Chorionic Gonadotropin (hCG) market size, share, trends, overall earnings, gross revenue, and profit margin to accurately draw a forecast and provide expert insights to investors to keep them updated with the trends in the market.

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The research on the Human Chorionic Gonadotropin (hCG) market focuses on mining out valuable data on investment pockets, growth opportunities, and major market vendors to help clients understand their competitors methodologies. The research also segments the Human Chorionic Gonadotropin (hCG) market on the basis of end user, product type, application, and demography for the forecast period 20212027. Comprehensive analysis of critical aspects such as impacting factors and competitive landscape are showcased with the help of vital resources, such as charts, tables, and infographics.

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The belief that ‘real men don’t see doctors’ may be why fewer women succumb to Covid | Citypress – News24

Statistics show that men are less likely to present themselves for early Covid-19 screening and testing. Picture: Wire Photo

NEWS

Men are notorious for avoiding doctors rooms but during the coronavirus, when more men in the country are dying of the disease than women, today, which is Fathers Day, might be a good time to get real about mens health.

According to Fridays statistics released by Health Minister Zweli Mkhize, 903 men have so far succumbed to Covid-19 in the country, as opposed to 832 women and the toll the virus is taking on men is seemingly no different anywhere else in the world.

Experts told City Press that the situation was a cause for concern and necessitated honest, real conversations between health officials and men, as well as among men themselves, particularly since June is Mens Health Month.

Numerous studies overseas have also noted the link between gender and the severity of Covid-19.

For instance, in a study done in Tongji Hospital in Wuhan, China (the original epicentre of the pandemic) and published in the British Medical Journal on March 26, of a group of 799 people with the virus, 113 died. Of these, 73% were men.

A bigger study in the New York City area, published in the Journal of the American Medical Association JAMA on April 22, analysed the clinical data of 5 700 Covid-19 patients admitted to 12 hospitals in New York City, Long Island and Westchester County in the New York City area between March 1 and April 4.

Its also believed that the extra X-chromosome in women, which is linked to their sex chromosome, oestrogen, may be part of the reason females have a better immune response to Covid-19

Of the collective study group, 60.3% were men, a significant number of whom suffered from comorbidities such as diabetes, hypertension, cardiac illness and kidney disease.

Mortality rates were higher for males at every 10-year age interval after 20.

Experts havent reached consensus on why gender should influence survival rates.

In South Africa, Dr Marion Morkel, chief medical officer at Sanlam, said: It would appear that the hormone testosterone does influence the severity of the disease.

The irony is that thereve been two schools of thought on how it does so: some researchers have postulated that where theres a lowered level of testosterone in men, we see a lowered immune response, so they tend to get a more severe viral load.

Read:Opinion | When help is unavailable in times of need

"However, a very high level of testosterone has also been shown to influence the severity of disease, as it appears to cause an over-response of the immune system. Scientists arent sure whether one has a greater influence over the other.

Its also believed that the extra X-chromosome in women, which is linked to their sex chromosome, oestrogen, may be part of the reason females have a better immune response to Covid-19.

However, theres also a notion that males risk-seeking behaviour is slightly different from that of females.

This is more pronounced in the Northern Hemisphere, so when social distancing started being put into place in those countries, more males than females pushed the boundaries of the restrictions, thus exposing themselves to the virus more often.

In addition, said Morkel, men were more likely to have chronic lifestyle illnesses such as ischaemic heart disease and diabetes, among other comorbidities.

Further to that, men were less likely to present themselves for early screening and testing.

In fact, a 2019 Cleveland Clinic survey of 1 174 American men found that 65% of them would wait as long as possible to seek medical help if they had a health issue or injury, while 72% said theyd rather do unpleasant household chores like cleaning the toilet or mowing the lawn than consult a doctor.

Men also often dont deal with issues of sensitivity readily. Theyll talk about all manner of other subjects, but not about things that are uncomfortable and make them feel vulnerable, such as illness, disability or death

Explaining why men were seemingly so doctor-averse, psychiatrist Dr Ian Westmore said many males were culturally conditioned to take up the traditional masculine role of appearing emotionally and physically stable and strong to their own detriment.

Theres this idea of the superhero syndrome in [many cultures] where men keep up a macho expectation of being the strong ones, the providers whore always in control.

Theyre programmed to be like that from a young age, so perhaps going to a doctor implies a sort of vulnerability, making them feel quite exposed. They want to hide that for as long as possible. Theres also a fear of what if the doctor does find something wrong?, so theyll often sit with a problem for a long time [before seeking help].

Westmore added that male attitudes towards seeking healthcare was a problem which needed to be addressed.

Men also often dont deal with issues of sensitivity readily. Theyll talk about all manner of other subjects, but not about things that are uncomfortable and make them feel vulnerable, such as illness, disability or death.

Having Covid-19 is one of those red lights that need to go on. If you sit on your symptoms and dont go to the doctor, not only are you putting other people in danger, but your own condition could get much worse, [especially] if you have other underlying health issues, he said

Health Journalist

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The belief that 'real men don't see doctors' may be why fewer women succumb to Covid | Citypress - News24

Recommendation and review posted by Bethany Smith

Asia Endometriosis Therapies Market set to grow with massive rate by 2020 to 2025 – 3rd Watch News

Global Endometriosis Therapies Market Research Report Cover Covid-19 Impact

The Endometriosis Therapies market research report fabricated by Brand Essence Market Research is an in-depth analysis of the latest trends persuading the business outlook. The report also offers a concise summary of statistics, market valuation, and profit forecast, along with elucidating paradigms of the evolving competitive environment and business strategies enforced by the behemoths of this industry.

Download Premium Sample of the Report: https://industrystatsreport.com/Request/Sample?ResearchPostId=12189&RequestType=Sample

Endometriosis Therapies Market unveils a succinct analysis of the market size, regional spectrum and revenue forecast about the Endometriosis Therapies market. Furthermore, the report points out major challenges and latest growth plans embraced by key manufacturers that constitute the competitive spectrum of this business domain.

Therapies used totreat endometriosisinclude: Hormonal contraceptives. Birth control pills, patches and vaginal rings help control the hormones responsible for the buildup ofendometrialtissue each month.In this report, 2018 has been considered as the base year and 2019 to 2025 as the forecast period to estimate the market size for Endometriosis Therapies.

This report studies the global market size of Endometriosis Therapies, especially focuses on the key regions like United States, European Union, China, and other regions (Japan, Korea, India and Southeast Asia).

This study presents the Endometriosis Therapies production, revenue, market share and growth rate for each key company, and also covers the breakdown data (production, consumption, revenue and market share) by regions, type and applications. history breakdown data from 2014 to 2019, and forecast to 2025.

In this study, the years considered to estimate the market size of Endometriosis Therapies are as follows:

History Year: 2014-2018 Base Year: 2018 Estimated Year: 2019 Forecast Year 2019 to 2025

For top companies in United States, European Union and China, this report investigates and analyzes the production, value, price, market share and growth rate for the top manufacturers, key data from 2014 to 2019.

In global market, the following companies are covered:

AbbVie Eli Lilly AstraZeneca Bayer Astellas Pharma Meditrina Pharmaceuticals Pfizer Neurocrine Biosciences Takeda Pharmaceutical

Market Segment by Product Type

Hormonal Contraceptives Gonadotropin-releasing Hormone (Gn-RH) Agonists Progestin Therapy Aromatase Inhibitors

Market Segment by Application

Hospital Clinic Other

Key Regions split in this report: breakdown data for each region.

United States China European Union Rest of World (Japan, Korea, India and Southeast Asia)

Endometriosis Therapies market report consists of the worlds crucial region market share, size (volume), trends including the product profit, price, value, production, capacity, capability utilization, supply, and demand. Besides, market growth rate, size, and forecasts at the global level have been provided. The geographic areas covered in this report:North America (United States, Canada and Mexico), Europe (Germany, France, UK, Russia and Italy), Asia-Pacific (China, Japan, Korea, India and Southeast Asia), South America (Brazil, Argentina, Colombia etc.), Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa).

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. Top-down and bottom-up approaches are used to validate the global market size market and estimate the market size for manufacturers, regions segments, product segments and applications (end users). All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or other factors are not accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from BrandEssenceResearch and presented in this report.

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation, extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub segments listed in this report. Extensive qualitative and further quantitative analysis is also done from all the numbers arrived at in the complete market engineering process to list key information throughout the report.

The study objectives are:

To analyze and research the Endometriosis Therapies status and future forecast in United States, European Union and China, involving sales, value (revenue), growth rate (CAGR), market share, historical and forecast. To present the key Endometriosis Therapies manufacturers, presenting the sales, revenue, market share, and recent development for key players. To split the breakdown data by regions, type, companies and applications To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks. To identify significant trends, drivers, influence factors in global and regions To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market

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Key Reasons to Purchase:

To gain insightful analyses of the market and a comprehensive understanding of the impact of COVID-19 is likely to have on the Endometriosis Therapies Market during the forecast period between 2020 and 2026, and its commercial landscapeTo learn about the market strategies that are being adopted by your competitors and other leading companiesTo understand the future outlook and prospects of the Endometriosis Therapies Market post COVID-19To keep you abreast with the strategies used by other players in theTo understand the changes in rules and regulations in various countries during COVID-19 and its possible effects on the market in the future.

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We publish market research reports & business insights produced by highly qualified and experienced industry analysts. Our research reports are available in a wide range of industry verticals including aviation, food & beverage, healthcare, ICT, Construction, Chemicals and lot more. Brand Essence Market Research report will be best fit for senior executives, business development managers, marketing managers, consultants, CEOs, CIOs, COOs, and Directors, governments, agencies, organizations and Ph.D. Students.

Read the original post:
Asia Endometriosis Therapies Market set to grow with massive rate by 2020 to 2025 - 3rd Watch News

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