Cryonics TechnologyMarket reports provides a comprehensive overview of the global market size and share.Cryonics Technologymarket data reports also provide a 5 year pre-historic and forecast for the sector and include data on socio-economic data of global. Key stakeholders can consider statistics, tables & figures mentioned in this report for strategic planning which lead to success of the organization

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The report firstly introduced the Cryonics Technology basics: definitions, classifications, applications and market overview; product specifications; manufacturing processes; cost structures, raw materials and so on. Then it analyzed the worlds main region market conditions, including the product price, profit, capacity, production, supply, demand and market growth rate and forecast etc. In the end, the report introduced new project SWOT analysis, investment feasibility analysis, and investment return analysis. The report also presents the market competition landscape and a corresponding detailed analysis of the major vendor/manufacturers in the Cryonics Technology market.

The key players covered in this study, Praxair, Cellulis, Cryologics, Cryotherm, KrioRus, VWR, Thermo Fisher Scientific, Custom Biogenic Systems, Oregon Cryonics, Alcor Life Extension Foundation, Osiris Cryonics, Sigma-Aldrich, Southern Cryonics

Market segment by Type, the product can be split intoSlow freezingVitrificationUltra-rapid

Market segment by Application, split intoAnimal husbandryFishery scienceMedical sciencePreservation of microbiology cultureConserving plant biodiversity

Global Cryonics Technology Industry 2020 Market Research Report is spread across 92 pages and provides exclusive vital statistics, data, information, trends and competitive landscape details in this niche sector.

What to Expect From This Report on Cryonics Technology Market:

The developmental plans for your business based on the value of the cost of the production and value of the products, and more for the coming years.

A detailed overview of regional distributions of popular products in the Cryonics Technology Market.

How do the major companies and mid-level manufacturers make a profit within the Cryonics Technology Market?

Estimate the break-in for new players to enter the Cryonics Technology Market.

Comprehensive research on the overall expansion within the Cryonics Technology Market for deciding the product launch and asset developments.

Regions Covered in Cryonics Technology Market are:-

North and South America

Europe

China

South Korea

Japan

India

Research Objectives of Cryonics Technology Market:

To study and analyze the global Cryonics Technology consumption (value & volume) by key regions/countries, product type and application, history data from 2014 to 2020, and forecast to 2026.

To understand the structure of Cryonics Technology market by identifying its various sub segments.Focuses on the key global Cryonics Technology manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years.

To analyze the Cryonics Technology with respect to individual growth trends, future prospects, and their contribution to the total market.

To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).

To project the consumption of Cryonics Technology submarkets, with respect to key regions (along with their respective key countries).

To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.

To strategically profile the key players and comprehensively analyze their growth strategies.

Major Points from Table of Contents1 Study Coverage1.1 Cryonics Technology Product Introduction1.2 Key Market Segments in This Study1.3 Key Manufacturers Covered1.4 Market by Type1.4.1 Global Cryonics Technology Market Size Growth Rate by Type1.4.2 Specialty Gas Grade (Low Purity)1.4.3 Research Grade (High Purity)1.5 Market by Application1.5.1 Global Cryonics Technology Market Size Growth Rate by Application1.5.2 Nuclear Application1.5.3 Non-Nuclear Application1.6 Study Objectives1.7 Years Considered

2 Executive Summary2.1 Global Cryonics Technology Production2.1.1 Global Cryonics Technology Revenue 2014-20262.1.2 Global Cryonics Technology Production 2014-20262.1.3 Global Cryonics Technology Capacity 2014-20262.1.4 Global Cryonics Technology Marketing Pricing and Trends2.2 Cryonics Technology Growth Rate (CAGR) 2020-20262.3 Analysis of Competitive Landscape2.3.1 Manufacturers Market Concentration Ratio (CR5 and HHI)2.3.2 Key Cryonics Technology Manufacturers2.3.2.1 Cryonics Technology Manufacturing Base Distribution, Headquarters2.3.2.2 Manufacturers Cryonics Technology Product Offered2.3.2.3 Date of Manufacturers Enter into Cryonics Technology Market2.4 Market Drivers, Trends and Issues

3 Market Size by Manufacturers3.1 Cryonics Technology Production by Manufacturers3.1.1 Cryonics Technology Production by Manufacturers3.1.2 Cryonics Technology Production Market Share by Manufacturers3.1.3 Global Market Concentration Ratio (CR5 and HHI)3.2 Cryonics Technology Revenue by Manufacturers3.2.1 Cryonics Technology Revenue by Manufacturers (2014-2020)3.2.2 Cryonics Technology Revenue Share by Manufacturers (2014-2020)3.2.3 Global Cryonics Technology Market Concentration Ratio (CR10 and HHI)3.3 Cryonics Technology Price by Manufacturers3.4 Mergers & Acquisitions, Expansion Plans

4 Cryonics Technology Production by Regions

5 Cryonics Technology Consumption by Regions

6 Market Size by Type

7 Market Size by Application

8 Manufacturers Profiles

9 Production Forecasts

10 Consumption Forecast

11 Upstream, Industry Chain and Downstream Customers Analysis

12 Opportunities & Challenges, Threat and Affecting Factors

13 Key Findings

14 Appendix

In addition, this report discusses the key drivers influencing market growth, opportunities, the challenges and the risks faced by key manufacturers and the market as a whole. It also analyzes key emerging trends and their impact on present and future development.

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Cryonics Technology Market 2020: Qualitative Analysis of the Leading Players and Competitive Industry Scenario - Germany English News

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NEW YORK, April 7, 2020 /PRNewswire/ --Hormone Replacement Therapy Market Size, Share & Trends Analysis Report By Product (Estrogen, Human Growth), By Route Of Administration (Oral, Parenteral), By Type Of Disease, By Region, And Segment Forecasts, 2020 - 2027

Read the full report: https://www.reportlinker.com/p05879593/?utm_source=PRN

The global hormone replacement therapy market size is expected to reach USD 39.6 billion by 2027, expanding at a CAGR of 7.7%. A significant rise in the incidence rate of hormonal disorders in the newborns, adults, and elderly and populations is driving the market. The Prader-Willi syndrome (PWS) affects one in every 15,000 newborns, thereby boosting the demand for the therapy.

Estrogen replacement hormone therapy helps in reducing the vaginal indications of menopause, such as dryness, burning, itching, and pain during intercourse.Estrogen is available in the forms of pill, gel, skin patch, cream or spray form.

It is highly successful for treating problematic menopausal night sweats and hot flashes. Around 45% of women between the ages of 40 to 60 years of age were reported taking counseling sessions from a physician regarding the advantages and disadvantages of using hormone replacement therapy (HRT) after menopause.

Growing awareness about menopausal signs and the treatment options is growing the HRT market.Owing to the significant development for ERT, there has been an initiation of very safe treatment options for the patients situated in various geographies of the world.

For example, augmentation of innovative drug delivery systems like transdermal estrogen patches and vaginal estrogen drugs.

Further key findings from the report suggest: The estrogen replacement therapy segment dominated the overall market in terms of revenue share in the year 2019. On the other hand, the parenteral segment is likely to showcase the fastest growth rate over the forecast period from 2020 to 2027, owing to the rising number of hormonal disorders Menopause is likely to showcase the fastest growth rate over the forecast period. Women are vulnerable to certain diseases and conditions such as osteoporosis and hot flashes during and after menopause. About 73% of postmenopausal women suffer from hot flashes North America dominated the overall hormone replacement therapy market in terms of revenue share in the year 2019. The increase in the incidence rate of hypogonadism due to a rise in obesity and poor health in the geriatric population drive the market. According to the American Academy of Family Physicians, more than 2.5 million Americans received testosterone treatment in U.S alone in 2014 Some of the key players in this market are Abbott Laboratories; Novartis; Pfizer, Inc.; Mylan Laboratories; Merck and Co.; Novo Nordisk; Bayer Healthcare; Eli Lilly; and Genentech.

Read the full report: https://www.reportlinker.com/p05879593/?utm_source=PRN

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Hormone Replacement Therapy Market Size, Share & Trends Analysis Report By Product, By Route Of Administration, By Type Of Disease, By Region And...

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captionStress may cause gray hair prematurely.sourceManop_Phimsit/Shutterstock

Stress can affect the body in many different ways. And while it seems that stressful life events like being president may cause gray hair, the truth is a bit more complicated.

Gray hair is likely caused by a combination of genetics, aging, and hormones, and there is some research to suggest that stress can turn hair gray prematurely. Heres what you need to know.

When youre born, your hair color is determined by natural pigments in your skin called melanin.

Human hair follicles contain two types of melanin: eumelanin and pheomelanin, says Leann Poston, MD, a licensed physician. The wide diversity of possible hair colors comes from the production ratio of these two types of melanin.

Melanin is created from melanocytes, which are the cells found in your skin and hair follicles. When melanocytes stop producing melanin, your hair color changes to gray.

Melanocytes often stop producing melanin as you age, which is why gray hair is so common among the elderly. However, its common for hair to start turning gray around age 35.

Overall, Poston says that a combination of factors such as genetics, hormones, and your environment will determine exactly when your hair turns gray.

Though stress alone will not cause gray hair, there is some research that suggests it may speed up the graying process.

For example, a 2020 study published by the journal Nature found that when mice were exposed to stress, they lost melanocyte cells and gained gray hair as a result.

This is an interesting study that links stress to an abnormal conversion of stem cells to a more differentiated form, melanocytes, Poston says.

Melanocyte stem cells typically decrease in numbers as you age. But premature activation, associated with increases in a stress hormone called norepinephrine (or noradrenaline), actually caused these cells to decline more quickly in mice leading to the gray hair that researchers observed.

Poston says she doesnt believe this animal study is enough to definitively say that the same is true for humans. But other research has also suggested that stress can accelerate graying.

For example, a 2018 study in the International Journal of Trichology observed an increase in oxidative stress as a result of psychological stress and higher levels of oxidative stress, which contributes to a complicated biological imbalance in humans, are associated with an increased risk of many chronic diseases as well as premature aging.

The study suggests that premature gray hair, or the graying of hair by age 20, is linked with higher levels of oxidative stress, which may increase with more of your everyday psychological stressors like a difficult job or the pressure to provide for your family.

In addition, cigarette smoking and vitamin deficiencies which can also increase oxidative stress have been associated with early graying.

Overall, genetics and aging are likely to be more determinate for when your hair turns gray. But, as some research has suggested, psychological stress and other unhealthy risk factors may accelerate this graying process.

Read the rest here:
Does stress cause gray hair? It may lead to premature graying - Business Insider

Recommendation and review posted by Bethany Smith

For all of these reasons, stress-induced breakouts manifest in many different forms, so it's "impossible to generalize" about exactly how it will present itself (i.e. as blackheads or pustules or cysts), Marchbein explains, though she does note that cystic acne is "especially common with stress."

"Keeping routines can be profoundly helpful in times of unprecedented stress and uncertainty," Rieder says. "When we have seemingly lost control of [many of] the elements that give us peace, including our occupations, finances, and health, normalcy in any sense is welcome [and] things that we take for granted and often do automatically are important to maintain."

Perhaps number one on this list is sleep both getting enough of it and also trying to stick to regular sleep-wake hours. Sleep is crucial to our health for many, many reasons, however, as pertaining to overall skin health, the importance of getting your Zzz's ties back to cortisol. This is because when we're sleep-deprived, our bodies produce an increased amount of cortisol, which, as previously established, can spiral our skin out of balance.

Next on the list of important routines to maintain is "eating regular meals [and] having dedicated time both to yourself and for socializing, exercising, and practicing self-care in the way that you best respond to," Rieder explains. In terms of self-care, he personally recommends activities like meditation, yoga, deep breathing, exercise, and skin care, but the entire idea here is to take the time regularly to take care of yourself in a way that feels good to you.

It's also worth noting that one factor that can be both a source of self-care and stress is technology. While streaming an online exercise class is a highly recommended form of self-care among all the experts we spoke to, spending too much time on your phone or computer is not especially when it feels like terrifying news updates pour in on an hourly basis. Still, it's also important to stay informed.

Again here, it's about striking a balance that feels right to you and prioritizes your mental health. Rieder's recommendation: "Find one or two news sources that are trustworthy and spend no more than 30 minutes daily informing yourself," he says.

"It is easy to get attached to your only source to the outside world your phone and television during a time like this," Vega agrees. "While it is good to be connected, you also need to detox from the overwhelming stress of the world in general."

When it does spring up, stress pimples respond best to a few specific topicals: salicylic acid, benzoyl peroxide, and retinol, Marchbein and Vega explain. Each ingredient works in different ways to combat breakouts. Salicylic acid can unclog pores, benzoyl peroxide is anti-inflammatory and antibacterial, and retinol increases skin cell turnover rate.

That doesn't mean that you should use all three at once, however. Instead, Vega recommends using retinol as a long-term solution, and keeping either a salicylic acid or benzoyl peroxide product in your medicine cabinet to use as a spot treatment as needed.

Pimple patches can also be used as a spot treatment for acne, Marchbein suggests. "These are hydrocolloid adhesive stickers that contain certain active ingredients such as salicylic acid and/or tea tree oil, which are delivered to the pimple while its in place," she explains. "By occluding the pimple, these active ingredients are able to penetrate the skin more deeply allowing them to potentially work better."

For large, painful acne, "I would typically recommend heading to your dermatologist for a steroid injection to reduce the pain and inflammation of cystic breakouts," Marchbein explains, however, "at this point, medical visits should be for true emergencies only."

If you do find yourself reaching for, touching, or picking at your skin more often than normal, Lee suggests covering trouble spots with a bandage, "or better yet, apply an acne spot treatment, a dollop of cream right over the pimple or the red bump," she says. "If you reach up to pick at the bump, you will be reminded that there is cream on the area and hopefully this will remind you to not pick at your skin."

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It might feel like were fighting a losing battle most of the time. As many of us stay home adhering to the UAEs social distancing regulations amid the coronavirus outbreak, a combination of anxiety, stress and boredom can have us skipping workouts, snacking constantly and generally eating our feelings.

That doesn't mean you should let guilt get to you or start some impossible diet, however. If you, like many other people right now, are struggling to maintain a healthy weight while stuck at home, then these simple bite-sized tips could help you get back on track.

Skipping meals can be very unhelpful, says Rita Martins, a clinical dietician with Mediclinic City Hospital. You may feel hungrier later and overdo it on unhealthy snacks.

To ensure you dont do this, Nadine Aoun, a clinical dietician at Medcare Women and Children Hospital, advises trying to maintain the same routine you have at the office. She suggests eating breakfast, lunch, dinner and a snack in between each meal.

You know what they say: Eat breakfast like a king and Aoun is someone who subscribes to that belief. Never skip breakfast, she says.

Rawan Nucho, clinical dietician at Aligned Health by Right Bite, agrees. Starting your day with a balanced breakfast consisting of proteins, carbs and good fats keeps you fuller longer.

Dr Ruba El-Hourani, a clinical dietician at RAK Hospital, says some studies have shown the influence of intermittent fasting to maintain healthier body weight. This is a great way, provided that its done properly.

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Read more: Is intermittent fasting a fast track to weight loss and anti-ageing?

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Stick to a daily routine with your exercise, eating, cooking and self-care, says holistic health and nutrition coach Jo Owen. Writing up a weekly meal plan can reduce waste, save money and give you focus by cutting down on faff.

This is the same advice Baraa El Sabbagh, a dietician, sports nutritionist and recipe book author, gives. If you fail to plan, then you plan to fail, am I right? Whenever you have your meals planned the week before or even the night before, youre a lot more likely to make better decisions. By doing this, you eliminate having to make last-minute decisions because youve reached an absurd level of dizziness because of hunger.

This is near impossible to do if your cupboards are laden with crisps, cookies or cake. But if you avoid the junk food aisles in the virtual or real supermarkets, then you wont be able to reach for them. Instead, have healthy snacks like unsalted and raw nuts, dark chocolate, fat-free popcorn, fruits and vegetables, says Aoun. She suggests having vegetable sticks with guacamole or hummus, low-fat Greek yoghurt with mixed frozen berries or an apple cut up into slices and smeared with organic peanut butter, for example.

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Read more: Our comprehensive guide to healthy snacking

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Holistic nutritionist Maria Marlowe, founder of Healthy by Marlowe, says to rely on the power of vegetables. Set a goal to fill 50 per cent of your plate with veggies at every meal, she says. The more vegetables we eat, the more full we feel on fewer calories. Vegetables effectively crowd out other less healthy foods, and provide us with an abundance of nutrients and fibre that we need to stay healthy.

Whats the Ideal Plate Ratio? Marlowe explains that on top of 50 per cent vegetables, we should be aiming for our plates to contain 25 per cent healthy protein and 25 per cent whole grains or additional vegetables, and then some healthy fat on top. For protein, this equates to about 85 to 115 grams of meat or one cup of beans or lentils. Healthy fats include olive oil or avocado. Eating this way will help you feel full and energised throughout the day, keep your immune system strong and curtail mindless snacking.

If youre not a professional chef, chances are there are a few bland meals in your repertoire. Keeping your meals exciting and flavourful will make sure you dont go reaching for the nearest ready-meal or ordering delivery instead. Add garlic, onion and lots of spices such as turmeric, oregano and rosemary to your meals, advises Dr Cherry Ezzat, an anti-ageing and functional medical practitioner at Dermalase Clinic.

Its easy to rely on packaged and processed foods during this time, says Marlowe. But we are very lucky to still have access to plenty of fresh food. She suggests ordering vegetables such as kale, collard greens, broccoli and cauliflower You may want to focus on longer-lasting produce, such as cabbage, winter squash, citrus, zucchini, apples, garlic and ginger. She relies on Greenheart Organic Farms in Dubai for her vegetable deliveries.

You may have heard this saying before, but perhaps youre not sure why its being said. Dr Ezzat explains that it simply means making sure you eat plenty of colourful fruits and vegetables, as they are high in vitamins and minerals. Each colour you eat adds to your general health, she says. Red protects against heart disease. Blue and purple prevent blood clots and delay cell ageing. Green inhibits carcinogens and boosts detoxification. Orange benefits skin and vision. The more you eat of these, the more you fill up on health-boosting, nutrient-dense foods instead of high-calorie junk.

Owen says we all need to put our focus on real food. Not foods with a list of ingredients you cant pronounce. The more healthy whole foods you eat with plenty of protein and healthy fats the less room youll have for higher calorie processed comfort foods. When you give your body what it truly needs, youll have fewer cravings for empty calories and junk food, which usually leads to consuming fewer calories overall.

There are a few ingredients Marlowe always makes sure she has in the pantry in order to make quick and easy healthy meals. This includes coconut milk and curry paste. I always keep these on hand to whip up my favourite red Thai curry, she says. Simply add fresh or frozen vegetables and a protein of choice and you have a satisfying, flavourful meal ready faster than delivery. Be sure to choose a curry paste without added sugar. She uses Thai Kitchen products.

Instead of opting for regular pasta, try buying a variety with fewer calories, says Marlowe. There are so many naturally gluten-free bean and legume-based pastas on the market now that taste great and provide more fibre and protein compared to traditional pasta. I recommend throwing a steamer basket full of chopped vegetables like broccoli, cauliflower and squash over your boiling pasta water for a super-quick pasta primavera. Simply add some garlic sauted in olive oil and a little salt and pepper.

A number of studies have shown that omega-3 fatty acids have a range of healthy benefits and this includes reducing symptoms of metabolic syndrome, a collection of conditions that encompasses belly fat, as well as decreasing fat in your liver. Marlowe suggests keeping jarred wild sardines or anchovies in your pantry at all times. These are a quick and convenient omega-3-packed protein source that can be added to various different dishes.

Upgrade your comfort foods, Marlowe advises. You can make just about any comfort food healthier and waist-line friendly. If you want to make ice cream, for example, she suggests blending up frozen bananas instead. For sweets, you can make cocoa-date truffles.

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Read more: Why not try these vegan gelato recipes?

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In these times of social distancing, food does bring joy and comfort and thats OK, says Dr El-Hourani. However, its important to be mindful of these extra calories and create a balance to ensure you dont go overboard.

She suggests focusing on your food while you chew. Eat without distraction of your phone, computer or TV, and eat slowly to savour and activate your senses.

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Read more: How to start your mindfulness and meditation practice

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What is that, you ask? At its core, intuitive eating is learning to tap into your intuition and honour your body, Owen explains. She suggests the following these three principles: Eat nourishing foods when you feel hungry without overdoing it; learn how to feel satisfaction from other areas of life without using food for comfort, satisfaction or feeling of belonging; learn to respect your body for all it does for you and youll naturally become more gentle and mindful with your choices.

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Read more: Learn all about intuitive eating

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This is one of El-Houranis top tips. Try to have your last meal at least three hours before going to bed, so that your body can digest it better. Good digestion, she says, is key to healthy weight management.

While I dont focus on calorie counting, it can be helpful to have an approximate calorie goal range, says Owen. Why not use the extra time to evaluate your food intake and choices? If you find yourself gaining weight, its not always the case that youre eating too much, she adds. If youve been eating too few calories, weight loss can stall, too. Try playing with the numbers and see what works. She advises using apps such as Cronometer and MyFitnessPal to track your food. Most of us carry our phones at all times, which makes tracking convenient.

Rawan Nucho, clinical dietician at Aligned Health by Right Bite, says its important to cut back on coffee. Sip more on herbal teas such as peppermint, cinnamon, chamomile, ginger and much more, as they keep your urge to snack low and can provide you with great [health] benefits.

Aoun says green or black teas are two of natures most potent sources of antioxidants, and sipping them regularly has been shown to decrease the risk of heart disease and stroke, to which people with diabetes are more susceptible. For the sake of your blood pressure, choose decaffeinated tea, she adds.

Its not just sugary drinks such as Coca Cola and Sprite we should be avoiding, but also juices, smoothies and milkshakes, says Aoun. [These are] high in calories, sugars and creamers. Again, she advises sipping on herbal teas or making homemade lemonade with artificial sweetener.

Not only does drinking water help with digestion and toxin elimination, says Owen, but its also an important element in our overall health and can be helpful with weight loss. Keep your water bottle with you throughout the day for regular sipping and add in fruits like lemon or orange slices, pomegranate or mint for added flavour and natural sweetness.

Aoun advises getting in at least eight to nine glasses of water per day.

El Sabbagh, who is also a personal trainer, says we should be moving our bodies for about 60 minutes per day in order to burn calories. This can definitely help with weight management, but the benefits of exercise definitely dont stop at physical health. While were at home, its important to also maintain a positive mindset and your mental health will improve tremendously by exercising at home, because of the endorphins and feel-good hormones released after breaking the slightest sweat.

El Sabbagh says you dont have to lift weights and swing kettebells around. Ive been working out using water bottles at home, you could put on a YouTube video, engage in bodyweight exercise, yoga, dancing, Pilates, step. You also dont need to do an hour in one go. It could be broken down into 30 minutes per session or even 15 minutes per session and continue to move two to three times per day, she adds.

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Read more: How to create a home workout space without spending a fortune

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Owen is a big advocate of keeping up an exercise routine while staying at home, but shes also aware it can get boring if you dont mix it up. When we exercise, our body releases endorphins that make us feel good and further motivate us towards eating sensibly, staying focused and keeping a positive mindset. She advises going online and using platforms such as Instagram and YouTube to find free workouts from local personal trainers and gyms.

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Read more: Try these virtual yoga classes with UAE instructors

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You dont have to do actual exercise to make sure you keep moving throughout the day. Stand up or walk around while you read and answer emails and other messages on your phone, Martins suggests. Set an alarm on your phone to remind you to take an activity break. For example, take a three to five-minute standing or walking break every hour. She also reminds us that household chores also count as exercise. Mop or vacuum fast enough to get your heart pumping.

Watch this video of mobility workouts you could try:

That being said, Owen also notes that if you feel like you need to rest, then rest. If youre already tired and feeling rundown, you would be better of getting the rest you need so you can recharge and give more effort at your next workout.

This is a big deal at the moment, says Owen. When youre under stress and / or youre not getting enough sleep, the stress hormone cortisol is elevated and this can hinder weight loss. When youre tired, youre also more likely to eat more. Studies show people consume up to 25 per cent more calories when theyre tired. This also leads you to crave a quick energy fix, she adds. This usually comes in the form of sugary snacks and drinks or processed foods.

Dr Ezzat says we need to aim for at least seven to eight hours of sleep per night.

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Read more: Having strange dreams? Find out what that means

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El Sabbagh, who is also a certified dietitian and recipe book author, says its important to know the difference between when youre hungry and when youre bored. Some of the food triggers while staying at home could be boredom, emotion or even habitual, she explains. For example, if something is bothering us we might stress eat or whenever we watch TV we might have a snack. Its important to ask ourselves every time we walk into the kitchen for a snack: Am I hungry or am I eating this out of boredom/stress/habit? If you realise youre not actually hungry, then its key to distract yourself, she adds. Try a new TV series or, better yet, do something with your hands. Some people take up knitting, reading, painting, drawing or doing a puzzle. Anything to keep the hangs and mind occupied instead of eating out of boredom.

Nucho suggests that, before you start snacking unnecessarily, you have a glass of water. If you cant decide whether youre actually hungry or bored, it might just be that youre thirsty. For some people, the feeling of thirst can be mistaken for hunger, and could make you want to reach for a sweet or salty snack, which in turn will make you thirstier. And thus, a vicious cycle emerges.

No matter what you do, maybe the number of the scales just keeps getting higher. Owen says: Its worth noting that there could be other underlying conditions, including hormonal imbalances, that can hinder weight loss. So, if you suspect this it might be a good idea to seek out a healthcare practitioner who deals with this, such as your physician, a naturopathic doctor or functional medicine doctor.

Martins stresses that amid the current crisis its important to focus on the present. Some days you will feel better than others, but dont stress and keep calm, even if some days you feel like you dont want to do anything. Try to motivate yourself and think about how it will be much harder to deal with after, if you end up with unwanted extra weight. As long as you motivate yourself to maintain the weight you currently have, then youre doing well, she adds. Relax and keep active.

Updated: April 13, 2020 07:57 PM

See the article here:
Worth the weight? 31 expert tips on maintaining a healthy size while staying at home - The National

Recommendation and review posted by Bethany Smith

Diabetes is so common you likely know someone who has it. Its a part of American life when 30.3 million Americans have diabetes. That breaks down to nearly 1 in 10 people who are managing the disease.

Because of the prevalence of diabetes, its important to have some knowledge of the disease. In fact, there are millions of people who are prediabetic or already suffering from the disease and dont yet have a diagnosis.

Diabetes has two main forms, type 1 and type 2 diabetes. What is thedifference between type 1 and type 2 diabetes?

Read on to learn about the disease of diabetes and its different types.

Causes of Type 1 Diabetes

Diabetes is technically one disease, although some consider the two types of different diseases. Your body has an immune system. This system is working to fight off things like bacteria and viruses to keep it healthy.

In a person who has type 1 diabetes, the immune system works in overdrive. It attacks some of the healthy cells in the body. These cells are the insulin-producing beta cells in the pancreas. Once the body does this to its own cells, it cant make insulin.

Insulin is an important hormone in the body. Insulin helps the body manage sugar, preventing it from getting too high or too low.

Causes of Type 2 Diabetes

Type 2 diabetes is a little bit different. In type 2, the body becomes resistant to insulin. The body makes it, but the insulin cant do what its intended to do.

This makes the pancreas think theres not insulin and it makes more. When the body doesnt use the insulin the glucose will build up in the bloodstream.

What Are the Symptoms of Diabetes?

Diabetes is a disease that can be managed. More on that later. But if the disease is not managed there are several symptoms that indicate your body is having a problem. Here are some general symptoms that show for both types of diabetes:

Not all diabetes sufferers will feel all the symptoms but these are the most common ones. They all connect back to how the body is managing or NOT managing the sugar and insulin.

Type 1 and type 2 might share some common symptoms but they present in different ways.

Type 1

Type 1 symptoms typically develop quickly. They show up suddenly and with many of them at the same time. Type 1 diabetes used to be referred to as juvenile diabetes because it more commonly shows up in children or adolescents.

In type 1 patients, in addition to the above symptoms, they often become moody or irritable. They might have sudden weight loss too.

Type 2

Type 2 diabetes patients develop their symptoms slowly. Many will already be diabetic for a while before the symptoms develop. Type 2 diabetes patients also will experience numbness and tingling in their hands and feet as a symptom too.

Risk Factors

There are some risk factors associated with diabetes. Type 1 diabetes cant be prevented. Type 2 diabetes can be avoided even if you have the risk factors by making some changes in lifestyle.

Lets take a closer look at some of the risk factors for both types.

Type 1

A person is at a higher risk for type 1 diabetes if they have a family history of type 1 diabetes. So, if they have a parent and or a sibling who already has the disease and develops symptoms, they should see a doctor right away.

As already mentioned, type 1 diabetes is most common in children and adolescents but it can develop at any age.

A study of genetics shows there are certain genes that make a person have an increased risk to develop type 1 diabetes. Its interesting to note that the further you live from the equator, the higher the prevalence of type 1 diabetes cases.

Type 2

Type 2 diabetes can be avoided. There are some risk factors to be aware of. If you are or have:

If you have ever given birth to a baby that is 9 pounds or more you also have a higher risk factor to develop type 2 diabetes. Also, if you have been pregnant and had gestational diabetes, you are at a higher risk.

You can lower your risk factors to develop type 2 diabetes by doing several things. These include:

People who eat a healthy and balanced diet with lower sugar intake and regular physical activity can reduce their chances of getting type 2 diabetes even if they carry some of the other potential risk factors.

Diagnosis and Treatment

If you are showing symptoms of diabetes, you should see your primary care physician. The doctor will order a test calledtheglycated hemoglobin (A1C) test. This test will look at your blood sugar levels for the last two to three months. If levels are consistently high, they know there is an issue.

As already stated, living a healthy lifestyle with a smart diet and physical activity will be part of managing diabetes.

Diabetes managementis required for type 1 patients. They dont make their own insulin, so it is necessary to get the insulin injected into their body. Some patients do injections several times a day. While other type 1 diabetics choose to wear an insulin pump that helps to provide it throughout the course of a day.

Type 2 patients are different. With the right diet and exercise regimen, they can actually control and reverse their diabetes. For some patients, diet and exercise are not enough and medications are needed as additional support.

Regular testing of blood sugar levels is a must as a diabetic. Blood sugar spikes or drastic drops can be life-threatening, so regular testing of the blood will be a part of any diagnosis.

Understanding the Difference Between Type 1 and Type 2 Diabetes

Diabetes is a serious disease but it can be managed with care and knowledge. Understanding thedifference between type 1 and type 2 diabetes is an important part of understanding the disease.

For more important health-related articles like this one, be sure to visit our blog often.

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What is the Difference Between Type 1 and Type 2 Diabetes? - - VENTS Magazine

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What is hypopituitarism?

Hypopituitarism (also called pituitary insufficiency) is a rare condition in which your pituitary gland doesn't make enough of certain hormones. Your body can't work properly when important glands, such as your thyroid glandand adrenal gland, don't get the hormones they need from your pituitary gland. Hypopituitarism can develop very slowly, over several months or even over several years.

Hypopituitarism can be caused by:

Sometimes, the cause is unknown.

Symptoms can include one or more of the following:

Your doctor will check your hormone levels with blood tests. You may have other tests, such as an MRI of your pituitary gland, to help find the cause of your hypopituitarism.

Treatment usually includes taking the hormones you're missing, sometimes for life. Your doctor also will teach you how to take extra cortisone (a hormone) when you are sick or under stress. If a tumor is causing your hypopituitarism, you might need surgery to remove it and/or possibly radiation treatment. If needed, you can take medicine for infertility.

You will need to get regular check-ups. It's wise to wear medical identification, such as a bracelet or pendant, which provides information about your condition in case of an emergency.

You can expect a normal life span, as long as you regularly take the medications recommended by your doctor.

Editor(s): Craig Alter, M.D., Anne Klibanski, M.D., Janet Schlechte, M.D.

Last Updated: November 2017

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Hypopituitarism | Endocrine Society

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A new study, published online last week in the Journal ofClinical Endocrinology & Metabolism, has found that certain steroids usedfor the treatment of inflammatory conditions such as allergies, asthma, andarthritis could increase the risk of COVID-19, the disease caused by the novelcoronavirus.

Certain types of steroids, such as glucocorticoids, suppressthe immune system, making people vulnerable to catch the virus.

Researchers explained that people who take glucocorticoidsmay also have severe illnesses if they are infected by the new coronavirusbecause the drugs suppress the bodys steroid response to the infection.

The journals editor-in-chief Dr. Paul Stewart of theUniversity of Leeds, England, and deputy editors Dr. Ursula Kaiser of Brighamand Womens Hospital in Boston and Dr. Raghavendra Mirmira of the University ofChicago conducted the study.

The researchers said, People with primary adrenalinsufficiency (Addisons disease) and secondary adrenal insufficiency occurringin hypopituitarism should also take extra precautions.

Patients should increase their oral glucocorticoid dose bytwice if they experience symptoms such as fever and persistent dry cough. Theyshould continue doing so until the fever subsides. If their condition worsens,they will require injectable glucocorticoids.

The authors wrote, People with diabetes who contractCOVID-19 also appear to be at risk of more severe illness than those withoutdiabetes.

Studies from Wuhan, China, the epicenter of the coronavirusoutbreak, found that COVID-19 patients with hypertension and diabetes were atincreased risk of severe illness and death.

Dr. Stewart and his team wrote, In our professional lives,we have not witnessed a health care crisis of this magnitude and severity.

They also noted that scientists have learned how the novelcoronavirus enters the cells and how it spreads from person to person.

Some researchers have even found how the virus interactswith the endocrine system. The authors wrote, Endocrine-related targets are at theforefront of discovery science as we collectively tackle this pandemic.

Continued here:
Certain Types of Steroids Could Increase the Risk of Coronavirus - Myhealthyclick

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Bird keepers at the Smithsonian Conservation Biology Institute (SCBI) in Front Royal, Virginia, are celebrating the arrival of a female white-naped crane chick that hatched April 2. She is the fourth chick for parents Brenda and Eddie and is the 46th to hatch at SCBI. Animal care staff at SCBI have had great success producing chicks from cranes that have behavioral or physical impediments that prevent them from breeding. The chicks parents are one of the only white-naped crane pairs living at the research facility capable of breeding naturally. Prior to hatching, scientists confirmed the chicks sex using DNA samples takenfrom inside of the egg. Keepers are closely monitoring the chicks development while leaving the experienced parents to bond with their chick without interference. They report Brenda and Eddie are providing excellent care to their chick. There are an estimated 5,000 white-naped cranes living in the wild, and the species is listed as vulnerable by the International Union for Conservation of Nature (IUCN).

As a public health precaution due to COVID-19, the Smithsonians National Zoo and Conservation Biology Institute is temporarily closed to the public.Animal keepers and veterinary staff remain working on site at the Zoo and SCBI to provide the usual highest quality care for the animals.The Zoos legacy of conservation work extends beyond the public Zoo in Washington, D.C., to SCBI headquarters in Front Royal, Virginia. Scientists at this 3,200-acre campus study and breed more than 20 species. The sprawling environment allows for unique studies that contribute to the survival of threatened, difficult-to-breed species with distinct needs, especially those requiring large areas, natural group sizes and minimal public disturbance. SCBI scientists tackle some of todays most complex conservation challenges by applying and sharing what they learn about animal behavior and reproduction, ecology, genetics, migration and conservation sustainability.

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White-Naped Crane Hatches at the Smithsonian Conservation Biology Institute - Smithsonian's National Zoo and Conservation Biology Institute

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Hair removal is one of the most physically intimate worker-client relationship that (legally) exists. And as the coronavirus spreads throughout the country, governors in many states ordered nonessential businesses including salons and waxing/threading centers to temporarily shut their doors. If youve ever had your brows threaded or upper lip waxed, you know why: its impossible to maintain 6 feet of social distance while depilating a client's chin (or anything else).

Unsurprisingly, the approximately $5.7 billion appearance enhancement industry, made up primarily of small business owners, is going to take a massive hit, as are the primarily female service providers in it. Some of us customers are trying to keep our local salons afloat by purchasing gift certificates and thats absolutely something you should do if its within your budget and you value your local small businesses.

But when it comes to the services these trusted professionals have been providing us, were on our own until the end of state-enforced social distancing. So maybe, just maybe, as our natural hair colors grow in and our split ends assert themselves, the quarantine can also serve as a moment for women to reset our relationship with our body hair.

In other words: Lets all get a lot hairier ... and stay that way.

Transgressive acts arent always comfortable at first, especially when a lot of us are staring at our own faces more than ever in Zoom meetings. But a random hair growing out of your chin won't ruin your life, nor will a mild shadow on your upper lip. Maybe your face wont look so quite as angular with grown-out brows the look my friend dubbed the coronabrow but who cares? You only have to look to actresses such as Gaby Hoffman and Lily Collins, or models such as Natalia Castellar and Cara Delevingne for proof that bushy brows are beautiful.

Carpe diem et carpe pilus! Reject the norms that have long served as tools of social control over womens lives and bodies!

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Even though the Western beauty ideal for the female body is smooth and nearly hairless, the truth is that womens facial and body hair is natural and normal. The amount of hair a woman might have is determined by hormones and genetics, dermatologist Hal Weitzbuch told the blog Fatherly, though certain medical conditions, like polycystic ovarian syndrome and Cushings syndrome, can lead to an actual excess of facial hair on women.

But, really, any sort of facial hair is broadly perceived as unfeminine and an embarrassing problem to be solved, not just an excess caused by an underlying medical condition. And despite the broad prevalence of some minor facial hair in women, we devote a lot of time, money and mental space getting rid of the shadows on our lips, the perceived bushiness in our brows and the peach fuzz on our jaws.

Girls learn from the mass media, peers and even their own families that this sort of hair needs to be groomed upon arrival (which usually happens in puberty, whether its on their upper lips, chins, filling in their eyebrows or at the edges of their hairlines). I was no different: as a 10-year-old, I thought my eyebrows looked like thick, black caterpillars, so I cut them off with scissors, which turned out not to be the look I was going for.

And once we start dyeing, trimming, waxing, threading and otherwise depilating that hair, we spend more or less the rest of our adult lives doing so.

This beauty standard has been causing us grief for more than a century, if not longer. In her 2015 book Plucked: A History of Facial Hair, Rebecca M. Herzig describes how, in the early 20th century, physician after physician described the severe depression, self-imposed seclusion and nausea common to women afflicted with heavy hair growth particularly hair on the face.

It causes emotional distress in modern times, as well: A 2006 study of 88 women with suspected polycystic ovary syndrome who had unwanted facial hair found that 40 percent reported they felt uncomfortable in social situations, and 75 percent reported clinical levels of anxiety. (It also said they spent an average of 104 minutes per week dealing with the hair.)

Not being able to engage in professional body hair removal during the coronavirus outbreak will be a big change for a lot of women. Herzig notes that more than 99 percent of American women are regularly depilating, and 85 percent do so regularly; a 2017 YouGov poll found that 43 percent of women personally remove hair from their faces; and a British study in 2017 suggested that about a third of women who regularly wax do so exclusively at salons.

Undoubtedly, some of us are going to try waxing, threading, bleaching, depilating or tweezing at home; salon professionals discourage women from shaving the hair on their face because it leaves stubble.

Some of us, though, won't want to bother with the time commitment or the expense, what with the sudden need to homeschool kids and cook for ourselves while (hopefully) also holding down our regular jobs on our home wireless connections while stressing about the pandemic itself. If there were ever a time for women to reassess the money and effort we put into removing our facial hair, its now.

After all, there has not been such a widespread reason for all women to put this aspect of personal care on pause; the great hair removal debates have largely been seen as a matter of personal choice. But, as with other personal decisions made by women, the viability of that choice is influenced by the larger cultural moment.

Already prior to the pandemic, celebrities, ad campaigns and influencers had promoted the idea that keeping one's leg, armpit and even pubic hair natural is a normal and even trendy choice; in a way, facial hair is the last frontier. If all of us are recalibrating our priorities and most of us are cutting back on unnecessary expenses, given burgeoning unemployment and the crashing economy perhaps we can also reassess the stringent standards of feminine upkeep to which weve hewn.

Put another way: Is a little chin hair really what you want to be focusing on during a global health and economic crisis?

I realize that, with so many scary things happening in the world, people may hold tight to what they can control, and some personal care can be embraced as self-care. But this is a great opportunity to collectively recalibrate our expectations of feminine beauty, freeing both women and girls from centuries of discomfort, insecurity and external control.

So embrace your coronabrow: if nothing else, it could end up being summers hottest trend.

Read the rest here:
Coronavirus closures mean no lip waxing or brow threading. Maybe that'll be good for us. - NBC News

Recommendation and review posted by Bethany Smith

Now that lambing is essentially finished at Lyons, we are focused on setting up the grazing rotations for the various groups of sheep we have on the farm.

his year we have five main grazing groups. These include the ewe lambs and their lambs, the 'main flock', Jonathan Higgins' two grazing groups for his research study and a small group of triplet-rearing ewes.

The triplet-rearing ewes are receiving 750g of concentrate per day at this stage. These lambs will be weaned onto a crop of Redstart in late May. The preparation for the sowing of this crop began last week, with an area towards the bottom of the hill sprayed off in advance of cultivation. This will also allow us an opportunity to reseed this section of the hill next near.

We run the ewe lambs as a separate group up to weaning to reduce competition from the mature ewes. We find this works well and gives this important group the best chance of hitting their mating targets in October.

The ewe lambs merit special attention because they are the future of the flock and should represent the best genetics within your breeding female population.

If you do not view them and treat them as such, then the question needs to be asked as to why they are being retained within the flock. Too often, ewe lambs are an after-thought; this should not be the case.

After a rather cool March, which had a negative impact on grass growth, growing conditions are improving across the farm.

In March our average temperature was 0.5C below average, and while this does not seem like much, it was enough to have a negative impact on grass growth.

Luckily April has been much warmer, with an average temperature to date of 9.1C, which is over one degree above the average for this time of year.

Tonic

Rainfall in April so far is scarce, as it was in March. In March we received approximately 65pc of our normal rainfall, though this did follow on from an exceptionally wet February, which delivered three times the normal monthly rainfall.

Conditions are good now for grass growth and last week's sunshine was a welcome tonic for the lambs. Dry weather is a real catalyst for lamb growth.

This year we encountered a small outbreak of contagious ovine digital dermatitis (CODD) in the flock just before lambing. This is a rather contagious type of lameness, which does not respond to the normal treatments that work for foot rot.

It is a separate disease, but as we discovered this year, foot rot and CODD can be present in the same foot, at the same time.

Traditionally one method for differentiating between the two was the strong smell associated with foot rot, which is absent with CODD.

However, in our most recent outbreak we had animals with the symptoms of CODD and the smell of foot rot, indicating both diseases are present at the same time. These animals responded well to antibiotic treatment and the issue is pretty much resolved now.

The next four weeks will be focused on research to a large part, with the start of faecal egg sampling on the experimental ewes and lambs, lamb weighing at six weeks of age to indicate ewe milk production, and ewe condition scoring.

The main flock will continue in their rotation and we will also be paying close attention to the parasite forecasts for control of Nematodirus in the lambs.

Indo Farming

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Tommy Boland: Ewe lambs deserve special treatment - they are the future of your flock - Farm Ireland

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New Delhi:As the world reels from the impact of the Covid-19 crisis, which has also induced an economic recession, there are many working tirelessly at the forefront to tackle the challenge. In India, several women are working round-the-clock, seven days a week, to ensure the smooth functioning of key departments administration, diagnosis, prevention, research and cure.

ThePrint takes a look at some of those leading these efforts.

Preeti Sudan, secretary at the Ministry of Health and Family Welfare, has been working on aligning all departments to execute the Narendra Modi governments policies to prevent the spread of the disease. Beela Rajesh, health secretary of Tamil Nadu, has been proactive in engaging with citizens through her department and Twitter. The state currently has more than 600 active cases, one of the highest in the country.

Dr Priya Abraham, director of National Institute of Virology, Pune, has made a significant medical breakthrough by isolating the deadly coronavirus. This helps in understanding the disease better and finding treatment regimens.

Dr Nivedita Gupta, senior scientist at Indian Council of Medical Research (ICMR), is busy designing the treatment and testing protocols for the country while Dr Renu Swarup, secretary, Department of Biotechnology, is spending her time trying to find a vaccine.

Also read: Coronavirus has challenged & changed how worlds top scientists work to find a cure

A 1983 batch IAS officer from the Andhra Pradesh cadre, Sudan is usually seen leaving her office at Nirman Bhawan late at night.

An M.Phil. in Economics and postgraduate in Social Policy and Planning from the London School of Economics, Sudan also served the World Bank in Washington as a consultant.

Her ministry is the nodal agency for fighting the present coronavirus challenge. Sudan, along with Union Health Minister Harsh Vardhan, coordinates with sister departments in the central and state government. The two conduct regular reviews of the evolving situation.

She is also involved in the regular review of preparedness with the states and union territories. Also, she is the first point of contact for any query arising from Prime Minister Narendra Modis office or from the office of Union Minister, said a senior official from her ministry who did not wish to be identified.

She played a major role in the evacuation of the 645 students from Wuhan, China, the official added.

Among her cadre, Sudan has a distinguished track record of serving in finance, disaster management, tourism and agriculture.

Also read: How experts are using maths to stay ahead of the coronavirus

Working in the Division of Epidemiology & Communicable Diseases, and in-charge of viral diseases at the countrys apex health research department, Dr Guptas primary responsibility is building testing and treatment protocols in India.

She was also the primary scientist involved in the investigations and containment of the Nipah virus outbreak in Kerala last year.

An MBBS from Lady Hardinge Medical College, Dr Gupta is the key person to augment the Covid-19 diagnostic capacity all across the country. In the short time span of two months, over 130 laboratories in the government sector and 52 laboratories in the private sector were roped in to diagnose coronavirus cases.

She worked day and night, including Sundays, to investigate the Nipah cases last year. It was not even a pandemic like coronavirus. Nowadays, for several days together, several scientists stay in the office to conclude the investigations, including her, said an official in her department, also on the condition of anonymity.

Gupta has a PhD in molecular medicine from Jawaharlal Nehru University and has been instrumental in setting up the virus research and diagnostic laboratory network of ICMR. This network was established subsequent to the 2009 pandemic influenza outbreak. The Virus Research and Diagnostic Laboratory (VRDL) network of 106 laboratories is largely considered as the backbone of the nation, and has ensured the capacity to detect the virus in almost all parts of the country.

Dr Gupta has aggressively investigated the viral outbreaks such as enteroviruses, arboviruses (dengue, chikungunya, Japanese encephalitis & Zika), influenza, measles and rubella among others. She was part of the team that worked extensively on deciphering the aetiology, and developed management guidelines, for the acute encephalitis syndrome in different parts of India.

Also read: Pancreatitis drug trials to a wastewater test for tracking virus top research on Covid-19

Swarup has been working at the Ministry of Science and Technologys Department of Biotechnology (DBT) for the past 30 years. She held the position of Scientist H which denotes an outstanding scientist until April 2018, when she was appointed as secretary.

A key person in the formulation of the Biotechnology Vision in 2001, the National Biotechnology Development Strategy in 2007 and Strategy II in 2015-20, Swarup is now involved in the crucial research to develop a coronavirus vaccine.

In an interview to ThePrint, Swarup had said that she is busy scaling up the manufacturing capacity of start-ups that have made low-cost testing kits and ventilators for Covid-19.

Her ministry has asked all IIT incubators to focus on research and development of portable ventilators, genome sequencing and isolation of the strain of the novel coronavirus from blood samples.

A PhD in Genetics and Plant Breeding, Swarup is known for promoting women in science, and was a member of the Task Force on Women in Science, which was constituted by the Scientific Advisory Committee to the Prime Minister.

Also read: 5 new projects India will pursue to find treatment for Covid-19 and similar diseases

Abraham leads the backbone of the country right now the National Institute of Virology (NIV), Pune, which is affiliated to the ICMR. The NIV was initially the only testing centre in the country for Covid-19.

As the number of cases spike on a daily basis, the NIV has succeeded in reducing the testing time of Covid-19 samples to just four hours a sample from 12-14 hours.

The NIV had confirmed the first three positive Covid-19 cases in India. The institute had initially done all the testing, but ICMR subsequently increased the number of laboratories, anticipating a jump in cases. Under Abrahams leadership, theNIV helped these labs with troubleshooting, and ensured reagent supplies to the network of labs.

The achievements which NIV has made at this crucial juncture were not possible without a hardworking and well-coordinated team, Abraham told ThePrint.

Abraham holds an MBBS, MD (Medical Microbiology) and PhD from Christian Medical College in Vellore, where she was also the former head of the department of Clinical Virology at CMC Vellore. She is also a fellow of the Royal College of Pathologists and Royal Society of Tropical Medicine and Hygiene. On invitation from the Medical Council of India, Abraham also drafted the syllabus for the Doctor of Medicine (DM) in Virology.

Her achievements also include being a key member of the WHOs Guidelines Development Working Group Meeting for Hepatitis and HIV in 2012, and for Hepatitis B in 2014. In 2017, she served as WHO consultant in Myanmar to formulate the National Hepatitis Testing.

Also read: India Covid-19 death rate lower than Italy, UK, but cant play down virus impact: NIV chief

As the health secretary of Tamil Nadu, Rajesh has been at the forefront of tackling the challenge in her state.

A 1997 batch IAS officer, she is known as a media-friendly bureaucrat and is very active on Twitter.

Virus can affect anyone, lets be gentle and sensitive towards each other and wage a coordinated battle against Covid19, she posted recently.

Apart from sharing her thoughts, she also responds to queries directed at her or her department.

An MBBS graduate from Madras Medical College, Beela earlier served as sub-collector of Chengalpattu, commissioner of Fisheries and commissioner of Town and Country Planning in Tamil Nadu. She was also the commissioner of Indian Medicine and Homeopathy before being transferred as the health secretary in 2019.

Tamil Nadu ranks third among all Indian states in the NITI Aayog Health Index given its vastly improved health outcomes.

Under Rajesh, the Tamil Nadu Health System Reform Program was set up with the state government, Centre and World Bank signing a $287 million loan agreement in June 2019. The program aims to improve the quality of health care, reduce the burden of non-communicable diseases (NCDs), and fill equity gaps in reproductive and child health services in Tamil Nadu.

Also read: These are the 11 Indian women scientists the new STEM chairs are named after

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Doctors, IAS officers & a scientist the 5 women leading Indias fight against Covid-19 - ThePrint

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United States, Wisconsin, Waukesha 04-13-2020 (PRDistribution.com) Dr. Victoria J. Mondloch, Medical Director of Wisconsin Stem Cell LLC and President/Founder of Victoria J. Mondloch, MD, SC., has recently been selected for the Empowered Woman of the Year Award for 2020 by the International Association of Top Professionals (IAOTP). Her exemplary role as a female business professional in a male dominated industry displays her influence, capability and determination.

While inclusion with the International Association of Top Professionals is an honor in itself, only a few women are chosen for this distinction based on their years of experience, professional accomplishments, academic achievements, leadership abilities and contributions to their communities. With innovation and compassion, these women empower others to reach their goals, while creating change for future generations.

Stephanie Cirami, President of IAOTP stated that Choosing Dr. Mondloch for this honor was an easy decision for our panel to make. She is a pro-active physician, who is insightful and empathetic in all aspects of her treatments. Dr. Mondloch displays empowerment through her ability to listen and understand her patients and staff. We are thrilled to be honoring her this year at IAOTPs Annual Awards Gala being held at the Plaza Hotel in New York City.

Dr. Mondloch is being recognized for having over three decades of professional experience as a Physician practicing Womens Health, Family Medicine, Preventive Health and Wellness for Women and Men. She is also a successful Author and Educator who empowers her patients to choose healthier options in order to lead a healthier lifestyle. She utilizes both traditional and integrative methods to enhance her patients course of treatment. Dr. Mondloch earned her MD from the Medical College of Wisconsin, did her internship in Internal Medicine and her residency in OB-GYN at St. Josephs Hospital in Milwaukee, WI.

Her practice and areas of expertise include but are not limited to: practicing traditional and non-traditional Family Medicine with an emphasis on Wellness and Preventive Health, Bio-identical hormone balancing including female/male sex hormones, Adrenals, thyroid and insulin with diabetes prevention as well as diabetes management, in-Office laboratory services, in-office supplements, vitamins and essential oils and in-Office sports medicine/Chiropractor services including Sarapin trigger point injections for muscular pain and paresthesia or numbness caused by nerve entrapment to upper and lower extremities. Dr. Mondloch practices a multi-faceted approach to common diagnoses such as abnormal periods, PMS, uterine fibroids, endometriosis and ovarian cysts, using hormone balancing to help prevent surgery. Other common diagnoses that are routinely addressed include: fibrocystic breast disease, polycystic ovarian disease, migraines, hot flashes/night sweats, insomnia, urinary incontinence, vaginal atrophy, low libido, abdominal bloating, fibromyalgia, Heart palpitations, Fatigue, Constipation, Headaches, Acne, excess facial hair, sciatica, low back pain and Hair loss with in-office all natural hair care products that help stimulate hair follicles to regenerate new hair growth. Dr. Mondloch practices a patient-centric style of medicine, dedicated to educating and empowering her patients to help them understand their health and help them get off of medication and remain out of the healthcare system.

Throughout her remarkable career, Dr. Mondloch remains active in her community, and has been recognized worldwide for her outstanding leadership and commitment to the profession. For 2020 she was featured on the famous Reuters Building in Times Square, NYC. In 2019 she graced the front cover of TIP (Top Industry Professionals) Magazine and she was selected as Top Medical Director of the Year by IAOTP where she was honored at their Annual Awards Gala at the Bellagio Hotel in Las Vegas.

Aside from her successful career, Dr. Mondloch is also a sought-after speaker and published author. She is the author of 2 books: Blossoming; Becoming a Woman and Full Bloom: Perimenopause, Menopause, Post-Menopause and Beyond. Blossoming is a mother-daughter guide to the pitfalls of hormone imbalance in the adolescent female and how to recognize the signs and symptoms as well as how to work with your healthcare provider to check hormone levels and correct imbalances. Blossoming is the 1st of a 3 book female book series that is planned to address hormone imbalances in women of multiple ages and stages. Full Bloom is the 3rd of a 3 book female book series that is planned which addresses hormone imbalances in women going through the rollercoaster of symptoms and hormone imbalances of perimenopause and then the safety profile and multiple health advantages of continuing to balance hormones into a womans postmenopausal years. Dr. Mondlochs 2nd book is for the multiple hormone pitfalls that accompany the menstruating female in her 20s, 30s and 40s and her 4th book is for hormone balancing in men. Dr. Mondloch was also featured in a 10-week radio series on CUTV News Internet Radio regarding adolescent health and a 10-week Radio series on CUTV News Internet Radio to help promote Full Bloom, Perimenopause, Menopause and Beyond. Dr. Mondlochs radio shows are archived on CUTV News Internet Radio by checking her website, victoriajmondlochmdsc.com and find her shows by date on the media page.

Moving forward, Dr. Mondloch has further expanded her practice to include the ability to more accurately target a patients specific organ systems and allow her patients own genetics to help guide their medical journey to wellness in a personalized and very individualized way.

Dr. Mondloch attributes her success to her perseverance, strength, her positive attitude and her passion for helping her patients. She has an in-office practice as well as a telemedicine preventive medical practice to offer medical advice to patients both in-office and remotely. When not working she enjoys traveling and spending time with her husband and 3 highly successful adult daughters. For the future, she will continue to grow as a professional and wants to continue to make a difference in peoples lives anyway that she can.

For more information on Dr. Mondloch please visit https://www.linkedin.com/in/victoria-mondloch-23b373/

To view her Video Biography please visit:

About IAOTP

The International Association of Top Professionals (IAOTP) is an international boutique networking organization who handpicks the worlds finest, most prestigious top professionals from different industries. These top professionals are given an opportunity to collaborate, share their ideas, be keynote speakers and to help influence others in their fields. This organization is not a membership that anyone can join. You have to be asked by the President or be nominated by a distinguished honorary member after a brief interview.

IAOTPs experts have given thousands of top prestigious professionals around the world, the recognition and credibility that they deserve and have helped in building their branding empires. IAOTP prides itself to be a one of a kind boutique networking organization that hand picks only the best of the best and creates a networking platform that connects and brings these top professionals to one place.

For more information on IAOTP please visit http://www.iaotp.com

Media Contacts:

Company Name: iaotpFull Name: Leah MontelloPhone: 2126344427Email Address: Send EmailWebsite: http://www.iaotp.com

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Dr. Victoria Mondloch selected as Empowered Woman of the Year by the International Association of Top Professionals (IAOTP) - Life Pulse Health

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Grace Mitchell cant wait to get on the road again.

And when she hits the road this time, shell be bound for Anchorage, Alaska, to take part in the Mayors Midnight Sun Marathon on June 17.

Grace will be participating in a 26.2 mile walk, sponsored by the Leukemia Society of America.

I completed the Honolulu Marathon in December of 1998, Grace said. I raised almost $5,000.

This is Graces second year as part of the Leukemia Societys Team in Training program. Money raised during the marathon is given to researchers at the Mayo Clinic, Hughs Institute and the University of Minnesota. Research funded in the past by the Leukemia Society has helped to develop new treatments for other cancers as well. Funds raised this year will be used to fight leukemia, myeloma, lymphoma, and Hodgkins disease. Grace and her husband own a summer cabin on Mille Lacs Lake and have been coming to the area for many years.

Inspired by his story in the Messenger, Grace is walking this year in honor of Abel Vanderpoel, son of Mary Jo and Keith Vanderpoel of Onamia.

Abel Vanderpoel was diagnosed with leukemia in September. He recently received stem cells from his sister Betsy and is undergoing treatment at Fairview Medical Center in the Twin Cities.

Grace will also be walking in memory of Patrick Kluck, who passed away in July of 1990 from leukemia.

Although not official honorees this year, in my heart, I will also be walking in memory of Catherine Malmquist and to honor Tanner Mielke, she said.

Two years ago, Grace was diagnosed with myelodysplastic syndrome, a pre-luekemia disease.

This is a cancer that attacks the bone marrow that produces the red blood cells, she said. At the present time, they do not know what causes the disease, and there is no cure. Thanks to tremendous prayer support, my disease is stable. My hope and prayer is that by the time my disease progresses, a treatment an cure will be found through continuing research.

Teams in training began in 1968 in New York when a woman named Lucy Duffy wanted to do something positive in response to her husbands struggle with leukemia. As a runner in the New York City Marathon, she passed out pledge forms to solicit donations for each mile she completed in the race. Her husband lost his battle two months after she ran the marathon, but she had raised $22,000 in his honor. Last year, over 23,000 runners, walkers and cyclists participated in the worlds major marathons on behalf of the Leukemia Society of America.

The Minnesota Team in Training began in 1994 and has raised nearly $2 million for research and patient aid in Minnesota, South and North Dakota.

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Best of the Mess from April 5, 2000 - Walking in the midnight sun - Aitkin Independent Age

Recommendation and review posted by Bethany Smith

In recent reports, it has been said that the coronavirus takes a higher toll on menwith some experts warning that being male may be a risk factor for COVID-19, as much older age is.

In fact, a scientist who studies sex difference in viral infections at Johns Hopkins Bloomberg School of Public Health, Sabra Klein told the New York Times: Being male is as much a risk factor for the coronavirus as being old. People need to be aware that there is this pattern. Just like being old means youre at higher risk, so does being male. Its a risk factor.

She also said the vulnerability could be biological or behavioural, adding that women have more robust immune systems than men.

But a new study from the Centers for Disease Control and Prevention (CDC) is suggesting it may have more to do with biology than lifestyle. In particular, it may even have to do with genetics.

Male COVID-19 patients are more common than females, study finds. | Image source: iStock

In CDCs Morbidity and Mortality Weekly Report published on Monday (6 April), it is found that there is a higher prevalence of COVID-19 in males across every pediatric age groupincluding newborns and infants.

Specifically, in the study of over 2,500 childrenaged 0 to 18with COVID-19, some 57 percent were male, suggesting that biological factors could make men more susceptible to the virus.

Based on the study, among the cases in children, the median age was 11 years, with nearly one-third of reported pediatric cases of cases involving teens between the ages of 15 and 17.

Among pediatric cases for which sex was known, 57 percent occurred in malesmuch higher in percentage compared to adult cases, in which 53 percent occurred in males.

The study also found that most of the children reported symptoms of cough or fever, only 5.7 percent were hospitalized.

These data support previous findings that children with COVID-19 might not have reported fever or cough as often as do adults, the report said.

Children who were hospitalised reported at least one underlying health condition, with most common being chronic lung diseases (such as asthma), cardiovascular diseases.

Meanwhile, in Singapore, a quick check on the summary of made available since the beginning of April shows that among the 21 reported pediatric patients who tested positive for COVID-19, 16 are male. Furthermore, based on this online dashboard, among the 49 pediatric cases reported here as of 11 April, 29 are male.

Still, it is noted that the research is still in its preliminary stages and that the authors are working with limited information. It is noted that the research did not suggest that parents should now be more concerned about their male childrenmore than their female childrengetting severely ill from COVID-19. Experts said it is no reason for parents of boys to panic, and for parents of girls to think they are immune to the virus.

24 hour clinics in singapore, Male COVID-19

Image source: iStock

They also reiterated that the risk for children remains very low. In fact, though there have been multiple reports from all over the world about coronavirus-related death in children recently, only 0.1 percent of the children infected died.

Story continues

View original post here:
COVID-19: Young Boys At Higher Risk Of Infection and Severe Illness From Coronavirus, Says Study - Yahoo Singapore News

Recommendation and review posted by Bethany Smith

Marisa Thompson, Southwest Yard and Garden Published 3:12 a.m. MT April 12, 2020

Small fruit are developing at the base of the female flower (bottom left), but not on the male flower (top left). Pollen from the stamens in the center of the open male flower (top right) can be translocated to the stigma in the center of the open female flower (bottom right) by pollinating insects or by humans.(Photo: Abrahami, Wikimedia Commons)

Question: I would love to be able to grow both zucchini and watermelon this year, but I am hesitant because of problems with cross-pollination in the past. Any tips?

Seed to Supper online course participant, somewhere in New Mexico

Answer: First of all, for readers who dont already know about New Mexico State University'sSeed to Supper program through ICAN (Ideas for Cooking & Nutrition), this is a free, online, self-paced beginning gardening course that was first developed by the Oregon State University Extension Service and modified by our own NMSU Food Systems Specialist Sally Cassady to be web-based and New Mexico-oriented (https://ican.nmsu.edu/seedtosupper.html).

It sounds like the problems youve had in the past with zucchinis and watermelons may have been more about fruit set issues which could include pollination problems than cross-pollination. Cross-pollination can only occur within plants of the same species. The old gardening tip dont plant cucumbers next to squash or melons because theyll cross-pollinate and form bad fruit isnt true. NMSU Extension Vegetable Specialist Stephanie Walker confirmed: As long as the cucurbits are different species, its very unlikely theyll cross-pollinate. Zucchini is Cucurbita pepo and watermelons are Citrullus lanatus, so they wont cross-pollinate to produce viable seed.

Marisa Y. Thompson(Photo: Courtesy)

Plants in the cucurbit (gourd) family include melons, pumpkins, squashand cucumbers. Each of those different cucurbits includes plants of different species and genera (plural of genus). Remember, the scientific names of plants consist of two parts: the genus and the species. So musk melons scientific or botanical name is Cucumis melo, with Cucumis as the genus and melo as the species. Cucumber is Cucumis sativus, so even though musk melons and cucumbers are in the same genus (Cucumis), they are not the same species and wont be likely to cross-pollinate. Even if they did cross-pollinate, the evidence would not be visible in this years crop. If you saved seed from cross-pollinated fruit and grew it next year, you might get something cool and yummy, although its more likely to be undesirable. Pumpkins with green bumps could be the result of seeds that were saved from normal pumpkins crossed with green-warted gourds.

Its not just that plants from different species arent likely to cross-pollinate based on their genetics. Amanda Skidmore, NMSU Extension integrated pest management specialist for urban and small farms, explains that our pollinators are picky too: Interestingly, different pollinators will visit each plant because of the flower shape and inflorescence. For example, squash bees will visit zucchini, but not watermelon.Skidmore encourages gardeners to take some time to watch and see what different pollinators are visiting the two plants. There will be some overlap (honey bees, bumble bees), but some cool differences too.

For information, check out our NMSU Extension Guide collection for vegetables. Related titles include Starting Plants Early Outdoors, Spices and Herbs for the Home Garden, Home Vegetable Gardening in New Mexico and Growing Zones, Recommended Crop Varieties, and Planting and Harvesting Information for Home Vegetable Gardens in New Mexico.

As retired NMSU Extension Horticulture Specialist Curtis Smith explained in a 2008 column, cucurbits have separate male and female flowers on the same plant. You can recognize the male flowers because they do not have a small fruit behind them (more on this later). They produce the pollen needed to form the fruit, but they do not produce the fruit. The female flower, on the other hand, has a small fruit behind the flower even before it opens. The female flower cannot produce the pollen needed to cause the fruit to develop and is dependent upon insect (or human) pollinators to transport the pollen from the male flower. The male flowers begin forming before the female flowers form. So, it is possible to have cucurbits blooming, but not producing fruit. The time between the first development of male flowers and the female flowers depends on plant variety and environmental conditions. Your problem may just be that the female blossoms have not formed yet. They should be forming soon. However, if you see the female flowers on your cucurbit plants, but they are not "setting" fruit, then the problem may be that you do not have pollinators.

Smith also offers tips on how to pollinate your cucurbit flowers yourself: Each morning, collect pollen from the stamens in the center of the male flowers and then transfer that pollen to the stigma in the center of the female flowers. Use a small, soft-bristled paintbrush to do this. If you are successful, you should see small fruit forming within a few days. Leave some female flowers unpollinated (by you), so you can watch for the return of the natural pollinators to relieve you of the early morning effort of pollination.

A few years ago, I wasnt convinced that Id be able to tell the difference between male and female flowers on a squash plant. That is, until I looked closer. Both flower types are huge and bright orange-yellow, but if you look just behind the flowers, youll know when you find a female versus a male because theres a swollen fruit structure developing at the base of female flowers. In some cucurbits, that baby fruit will be more rounded, and in others more like a small pickle.

For gardening information, including decades of archived Southwest Yard & Garden columns, visit the NMSU Extension Horticulture page (http://desertblooms.nmsu.edu/), follow us on social media (@NMDesertBlooms), or contact your County Extension office (https://aces.nmsu.edu/county).

Marisa Thompson, PhD, is the Extension Horticulture Specialist for New Mexico State University and is based at the Agricultural Science Center at Los Lunas.

More Southwest Yard and Garden:

Read or Share this story: https://www.lcsun-news.com/story/life/2020/04/12/exploring-gourd-family-cucumbers-squashes-and-melons/5126335002/

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Exploring the gourd family of cucumbers, squashes and melons - Las Cruces Sun-News

Recommendation and review posted by Bethany Smith

A.I.has already gotten to almost sci-fi levels of emulating brain activity, so much so that amputees can experience mind-controlled robotic arms, and neural networks might soon be a thing. That still wasnt enough for the brains behind one ambitious startup, though.

Cortical Labs sounds like it could have been pulled from the future. Co-founder and CEO Hong Wen Chong and his team are merging biology and technology by embedding real neurons onto a specialized computer chip. Instead of being programmed to act like a human brain, it will use those neurons to think and learn and function on its own. The hybrid chips will save tremendous amounts of energy with an actual neuron doing the processing for them.

Biological neural networks can solve problems in unfamiliar situations independent of acquired knowledge due to their self-organizing properties, says the companys website. Fluid intelligence is an essential requirement for autonomous robots.

Bio-computing was first switched on with neurons from mouse embryos, but can now use human neurons. Cortical Labs can morph human skin cells back into stem cells and then induce them to grow into actual human neurons. This was a process originally developed by Japanese scientists who were looking to eliminate the controversy that comes with using human embryonic stem cells. These cells are so useful because they havent yet decided what their function will be. That means they can be manipulated into just about anything.

After the skin cells undergo their transformation into neurons, a nourishing liquid medium is used to embed them onto a tiny metal oxide chip that has an even tinier grid of 22,00 electrodes. It is these electrodes that speak to programmers about when to zap electrical inputs to the neurons, letting them know what kind of outputs they are getting.

Artificially created neurons turn out the same as neurons that would (hypothetically) be taken from your gray matter, except there is no brain invasion required. Something like that would cross over from science fiction to science horror.

Right now, these chips are close to processing things like a dragonfly brain, so there are still upgrades to be made. Remember spending hours at the arcade playing Pong? Chong is determined to teach the chips to play that retro Atari game, and being powered by neurons uses just a fraction of what they would if they were only functioning on computerized intelligence. Think about it. The human brain has over a billion neurons, and our level of intelligence runs on only about 20 watts of power. Thats more than enough to play a marathon session of Pong.

Biological computing is the new frontier of computational power efficiency, the website says.

By the way, this wasnt the first time Pong got scientific star power. A.I. company DeepMind used it, along with other early Atari games that might be collecting dust in your basement somewhere, to demo how algorithms modeled after human neuron functions could perform. DeepMinds software scored high enough to convince Google into buying it. Now Google is using that tech to control the monster air conditioning units in its data centers, where it gets unbearably hot from servers devouring enough energy to keep entire cities running.

Cortical Labs is currently using mouse neurons on its quest to get hybrid chips to play Pong, but it probably wont be long before they use mutant human neurons. Gnarly.

(via Business Insider/Cortical Labs)

Read the original here:
Cyborg computer chips will get their brain from human neurons - SYFY WIRE

Recommendation and review posted by Bethany Smith

Scientists at Lund University in Sweden showed long ago they could reprogram human cells into nerve cells and implant them into the brains of rats after a stroke. But would the cells form the vital connections needed to restore mobility and sensations like touch?

Now, they have early evidence that the answer to that question isyes. The Lund team turned skin cells into nerve cells, transplanted them into the brains of the rodent stroke models and observed them for six months. The new cells repaired the damage caused by strokes in the animals, the researchers reported in the journal PNAS.

The Lund University team transplanted the reprogrammed skin cells into the rats cerebral cortices, the region of the brain thats most commonly damaged by stroke. Then they used electron microscopy and other technologies to track the cells. That allowed them to see that the cells were making the connections needed to repair damaged nerve circuits.

Virtual Clinical Trials Online

This virtual event will bring together industry experts to discuss the increasing pace of pharmaceutical innovation, the need to maintain data quality and integrity as new technologies are implemented and understand regulatory challenges to ensure compliance.

We have been able to see that the fibers from the transplanted cells have grown to the other side of the brain, the side where we did not transplant any cells, and created connections, said co-author Zaal Kokaia, professor of neurology at Lund, in a statement.

RELATED: Restoring neurons to preserve memory after heart attack or stroke

Cell therapy has been proposed for treating stroke damage in the past, but efforts to make it a reality have hit some roadblocks. A stem cell therapy being developed by British biotech ReNeuron failed to hit its primary trial endpoint of improving arm and leg movements. ReNeuron has since turned in better results from a trial of its cell therapy for improving vision in patients with retinitis pigmentosa.

Meanwhile, academic researchers are testing a variety of other therapies aimed at repairing stroke damage. Last year, for example, Stanford researchers showed that blocking a particular microRNA prompted star-shaped brain cells called astrocytes to become neurons, which helped restore memory in rats.

The Lund team is now planning additional animal trials to study how their transplanted cells affect memory and other intellectual functions, they said. They will also watch the rats closely to make sure they arent experiencing side effects, and theyll study the impact of the transplants on regions of the brain.

Original post:
Cell therapy restores mobility and sensations in rodent models of stroke - FierceBiotech

Recommendation and review posted by Bethany Smith

Id argue that no ingredient exfoliates and smoothes the skin better than retinol. Beyond that, the vitamin A derivative also delivers a host of other benefits, by virtue of the fact that it boosts cell turnover which helps expedite the removal of dead skin cells, which then leads to fewer breakouts and a brighter complexion. Having one in your routine seems like a no-brainer, right? Au contraire: there are many retinol options out there including vegan retinol products for those who have skin that doesnt exactly thrive through the tingles.

The tingles Im talking about are what come with traditional retinol products; a slight or not-so-slight sting that lets you know retinol has made contact with your skin and begun its exfoliating process. For some, its NBD and hardly inspires a flinch. But for those with sensitive skin, it hurts like hell and ends up doing more harm than good.

Thankfully, there are plenty of serums and moisturizers made with retinol alternatives like bakuchiol or products made with all-natural ingredients that help ease the delivery of traditional retinol into the skin. If you want the smoothing benefits of retinol sans irritation, here are some of the best vegan retinol options to choose from.

Aya Natural.

The brand that believes that if an ingredient cannot be eaten, it should never be used to treat the skin is responsible for this 100% natural dark spot corrector made with olive oil-derived retinol.

Biossance.

For firmer, brighter and balanced skin, use this lightweight serum made bakuchiol, a retinol alternative that delivers the same level of smoothing and brightening benefits.

Drunk Elephant.

One of DEs most popular products is this night cream, formulated with one percent vegan retinol to diminish the look of sun damage, dark spots and more.

GoPure Actives.

Both retinol and the retinol alternative bakuchiol are included in this botanical-rich (geranium, aloe vera, white tea and more) serum for smoother-looking skin and diminishing the appearance of wrinkles.

Herbivore.

This jelly-like serum may be vegan but its infused with a heavy hitter list of ingredients for exfoliation and hydration: bakuchiol, poly-hydroxy acids, and blueberry stem cells, to name a few.

Josie Maran.

A truly innovative product, this skin serum includes pink algae which so happens to be rich in beta carotene that converts to retinol upon contact with the skin.

OleHenriksen.

Besides the Truth Serum, one of OleHenriksens most iconic products is this multi-beneficial night cream infused with bakuchiol, glycolic and lactic acids, and red algae extract for firmer and smoother skin.

REN Skincare.

In addition to 100 percent naturally-derived vitamin A, this soothing night oil is also infused with vegetable and plant extract oils to ease irritation often associated with retinol.

Sunday Riley.

Instead of retinol, this luxe overnight oil is made with esters of retinol to increase elasticity and decrease fine lines without irritating the skin.

The Inkey List.

This plant-derived and antioxidant-rich daily moisturizer delivers the exfoliating properties of bakuchiol and the moisturizing benefits of squalane and Sacha Inchi oil.

Our mission at STYLECASTER is to bring style to the people, and we only feature products we think youll love as much as we do. Please note that if you purchase something by clicking on a link within this story, we may receive a small commission of the sale and the retailer may receive certain auditable data for accounting purposes.

Link:
10 Vegan Retinol Products for Smoother Skin Minus the Irritation - STYLECASTER

Recommendation and review posted by Bethany Smith

People who develop Parkinson's disease at a younger age (before age 50) may have malfunctioning brain cells at birth, according to a study that also identified a drug that may help these patients.

At least 500 000 people in the United States are diagnosed with Parkinson's each year. Most are 60 or older at diagnosis, but about 10% are between 21 and 50.

Parkinson's is a neurological disease that occurs when brain neurons that make dopamine become impaired or die. Dopamine helps coordinate muscle movement.

Symptoms get worse over time and include slow gait, rigidity, tremors and loss of balance. There is currently no cure.

"Young-onset Parkinson's is especially heart-breaking because it strikes people at the prime of life," said study co-author Dr Michele Tagliati, director of the Movement Disorders Program at Cedars-Sinai Medical Center in Los Angeles.

"This exciting new research provides hope that one day we may be able to detect and take early action to prevent this disease in at-risk individuals," he said in a hospital news release.

For the study, Tagliati and colleagues generated special stem cells from the cells of patients with young-onset Parkinson's disease. These stem cells can produce any cell type of the human body. Researchers used them to produce dopamine neurons from each patient and analysed those neurons in the lab.

The dopamine neurons showed two key abnormalities: build-up of a protein called alpha-synuclein, which occurs in most forms of Parkinson's disease; and malfunctioning lysosomes, structures that act as "trash cans" for the cell to break down and dispose of proteins. This malfunction could result in a build-up of alpha-synuclein, the researchers said.

"Our technique gave us a window back in time to see how well the dopamine neurons might have functioned from the very start of a patient's life," said senior author Clive Svendsen, director of the Cedars Sinai Board of Governors Regenerative Medicine Institute.

"What we are seeing using this new model are the very first signs of young-onset Parkinson's," Svendsen said in the release. "It appears that dopamine neurons in these individuals may continue to mishandle alpha-synuclein over a period of 20 or 30 years, causing Parkinson's symptoms to emerge."

The study was published in the journal Nature Medicine.

The researchers also tested drugs that might reverse the neuron abnormalities. A drug called PEP005 already approved by the US Food and Drug Administration for treating pre-cancers of the skin reduced elevated levels of alpha-synuclein both in mice and in dopamine neurons in the lab.

The investigators plan to determine how PEP005, which is available in gel form, might be delivered to the brain to potentially treat or prevent young-onset Parkinson's.

They also want to find out whether the abnormalities in neurons of young-onset Parkinson's patients also exist in other forms of Parkinson's.

Read more:
Young-onset Parkinson's may start in the womb - Health24

Recommendation and review posted by Bethany Smith

Theres no doubt that as we get older, our skin's wants and needs begin to change. Whileskincare routines of our late teens andearly twenties might have focused heavily on oil-absorbing products that worked to keepbreakouts in check, as we enter our thirties, its likely that other, more pressingskin issues start cropping up. For instance, spots of pigmentation might start surfacing, fine lines may begin to form and skin that was once plump andglowing could appear lacklustre and dull.

The sorry truth is that as we enter our thirties, all of the stuff that makes our skin naturally healthy starts to deteriorate. By the time we get to our thirties, we have around 50% collagen left in our skin.Hyaluronic acid production also slows down and cellular turnover only hits us around every four to six weeks. Everything starts to slow down, says celebrity facialist, Michaella Bolder.

So what exactly does all of this mean? And how can we help minimise the affects of ageing on our skin? To help decode everything there is to know about caring for skin in your thirties, I caught up with some of the top skincare experts in the business. Unsurprisingly, I found that, for the most part, they all preached the same message: As we make our way into our thirties, certainingredients simply cannot be compromised on.

Keeping scrolling for the six products they seriously recommend and to shop the best formulas out there.

As we enter our thirties, its understandable to assume that well start experiencing less breakouts as natural oil production starts to decline. However, thats not to say that regularexfoliation isnt necessary anymore.

Just because breakouts are most associated with teenage years, acne can still occur well into our thirties. In my clinical practice I frequently see patients in their thirties with adult onset acne, says Dr Catherine Borysiewicz, Consultant Dermatologist at the Cadogan Clinic. Data suggests women are more frequently affected by adult acne compared with men. The exact reason for this is unknown, but felt to be related to fluctuating hormone levels: during periods or from birth control pills, and also during and following pregnancy. The role of stress is also becoming more apparent, she warns.

Not only do regular acid treatments encourage cell turnover (something that starts slowing down in our thirties), they can also help to exfoliate for a clearer, more radiant complexion. Just remember, only exfoliate once or twice a week and always follow up with SPF.

REN Clean Skincare Ready Steady Glow Daily AHA Tonic (27)

Medik8 Blemish Control Pads (26)

Paula's Choice Resist Advanced Smoothing Treatment 10% AHA (37)

This Works Morning Expert Multi-Acid Pads (33)

Weve heard it time and time again, but its true that no skincare routine is complete without some sort ofvitamin C product, especially if youre in your thirties. But what exactly is it, and what does it do? To start with, vitamin C is a very powerful antioxidant that works against skin-damaging free radicals such as pollution and UV. And unfortunately, by the time we reach our thirties, the effects of free radical damage start to become more and more evident. Vitamin C eradicates free radicals that have hidden within our skin cells that start to diminish our healthy cells, turning them into unhealthy, broken ones. It basically eats free radicals up like Pacman, says Bolder.

On top of that, vitamin C is great for treating pigmentation and lightening dark spots without altering normal skin tone. Leading aesthetic doctor and surgeon,Dr Mayoni also warns, In our thirties, pigment cells can start to become overactive and so the skin starts to look less plump, less hydrated and with more areas of pigmentation appearing.

Drunk Elephant C-Firma Day Serum (67)

Kiehl's Powerful-Strength Line-Reducing Concentrate (52)

La Roche-Posay Pure Vitamin C10 Serum (38)

SkinCeuticals C E Ferulic Serum (140)

As a rule, it tends to be that the older we get, the more potent and active our skincare needs to be. However, there is one particular product that we can never have too much of. Although it sounds scary, hyaluronic acid isnt actually an acid in the way that you might think. Whereas most acids work to exfoliate, hyaluronic acid is a powerful moisture-binder that occurs naturally in our skin.

What is a moisture-binder, I hear you ask? Able to retain up to x1000 its own weight in water, hyaluronic acid is able to hold onto any moisture and hydration in order to keep skin looking plump and supple. The bad news is that as we enter our thirties, our hyaluronic acid supplies start declining. Upon reaching our thirties, our natural stores of hyaluronic acid decrease, warns Rowan Hall-Farrise, Head of Global Education at QMS Medicosmetics. Not only does the amount that our skin naturally produces start to diminish, but years of exposure to free radicals also begins to wear our existing supplies down, hence why vitamin C is important. Are you keeping up?

Using a hyaluronic acid serum twice a day is essential and be sure to apply it 10 minutes before you use any retinol, advises Bolder.

Zelens Z Hyaluron Hyaluronic Acid Complex Serum Drops (55)

The INKEY List Hyaluronic Acid Serum (6)

Vichy Mineral 89 (25)

Eucerin Hyaluron-Filler Ultra Light Moisture Booster Gel-Cream (25)

Collagen might just be one of the most-mentioned words in beauty advertising, but its actually quite a complex thing. A naturally-occurring protein, collagen is the stuff that really helps hold everything together and support the skin, making it healthy, plump and bouncy. Just like hyaluronic acid, free radicals and ageing start to impact our collagen production as we get into our thirties. From the age of 25, our collagen production starts to decrease. Our late twenties and early thirties is when we should start incorporating collagen treatments into our regimens, says Hall-Farrise.

However, despite what beauty brands might tell you, supplementing collagen isn't as easy as slapping on a collagen-infused face cream - the molecules are far too big to be absorbed by the skin. Luckily, there are ways to encourage the bodys natural collagen production, but were warning you that they dont come cheap. The professional treatment of microneedling helps to stimulate collagen, but you can also use stem cell products at home. The stem cells are there to encourage collagen stimulation and preserve the collagen that we have left in our skin, says Bolder.

If you can't justify the expense, don't worry too much, keeping on top of your hyaluronic acid serums twice a day should be enough to keep skin looking plump and firm in the short term.

Augustinus Bader The Cream (205)

QMS Medicosmetics Collagen System Sensitive (199)

Sarah Chapman Skinesis Stem Cell Collagen Activator Duo (149)

Indie Lee Stem Cell Serum (127)

You knew this was coming, right? While its all too easy to switch off the minute you hear the word retinol (seriously, do we ever stop talking about it?), experts warn that now is actually the time to start paying attention. In fact, Bolder actually advises against using retinol any time before your mid-thirties. Retinol should not be in your early thirties, but in your mid to late thirties I recommend starting to use a retinol at around 1%, she says.

If youre totally out of the loop with exactly what retinol does and why its beautys ingredient du jour, let me explain. A form of vitamin A (dont be fooled by the word vitamin, this stuff is seriously powerful), retinol increases cell turnover and is thought to be one of the only skincare ingredients that can actually help reverse the signs of ageing. Dr Laura Hamilton, aesthetic doctor and founder ofVictor & Garth explains, Retinol can really do wonders for your skin. It can improve skin texture, reduce pore size and minimise the appearance of fine lines and wrinkles. In our thirties, most of us will see results with retinol.

But be warned, its not always fun and games. Side effects of redness and peeling can take some getting used to, so start with a lower strength twice a week at night time only and build up, says Dr Hamilton.

La Roche-Posay Retinol B3 Serum (39)

Sunday Riley A+ High-Dose Retinoid Serum (70)

Origins Plantscription Overnight Moisturiser (49)

Elizabeth Arden Retinol Ceramide Line Erasing Night Serum Capsules X 30 (38)

Sure, the importance of SPF application might not be specific to any one decade of your life, but its crucial to reiterate that it should always feature in your daily skincare routine if you want to protect your skin from sun damage and ageing. While daily sun cream application might have been considered a more preventative measure in your twenties, in your thirties you might be starting to notice the physical damage that prolonged sun exposure can cause. Sun damage starts to come through in your thirties. So while vitamin C and retinol are needed to help reduce the damage already caused, SPF every single day will help prevent any further sun damage, says Bolder.

The Body Shop Skin Defence Multi-Protection Lotion SPF 50+ (18)

Institut Esthederm Adaptasun Sensitive Skin Face Cream Strong Sun (30)

Medik8 Advanced Day Total Protect (55)

Shiseido Expert Sun Ageing Protection Lotion SPF30 (35)

Next up, I've done my research, and these are the best anti-ageing products.

This article originally appeared on Who What Wear

Read More from Who What Wear

Read more from the original source:
The 6 Skin Products Experts Say Every 30-Something Should Have in Their Routine - Yahoo Style

Recommendation and review posted by Bethany Smith

When Jeff Bezos, the Amazon kingpin, debuted his new muscular physique at the Sun Valley Conference in 2017, he almost broke the internet. His Vin Dieselesque guns launched countless memes about how the dweebs dweeb had transformed himself into a jacked-up specimen worthy of an action franchise.

In interviews Bezos credits his diet (which includes roast iguana and octopus for breakfast), his unwavering commitment to working out, and eight hours of sleep. But not everyone is buying it.

Clean livingthats the catchphrase, isnt it? quips Patricia Wexler, the ne plus ultra of Manhattan dermatologists. Very few admit to doing any procedures.

Not a chance its just diet and exercise, says Roberta Del Campo, a dermatologist based in Miami, the countrys plastic surgery capital. Behind the scenes these people are getting all sorts of injectables and body sculpting treatments, such as Emsculpt and Trusculpt Flex, which have surged in popularity, especially among men, in the last couple of years.

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Other experts suspect that captains of industry such as Bezos, who is 56, are going to even greater lengths to project vigor for both boards and broads. The tech titans are all looking much better than they used to, says Jessie Cheung, a Chicago-based cosmetic dermatologist whose holistic approach often involves testosterone and growth hormone substitutes, especially for men of a certain age who are lacking in muscle and look frail.

Access to bio-hacking tools such as stem cells and hormones is allowing men to look, perform, and think better. Its worth noting that Bezos, along with fellow billionaire Peter Thiel, invested in Unity Biotechnology, a company researching drugs and treatments to keep aging at bay. Im pretty sure hes gotten a taste of some good stuff, Cheung says.

Welcome to the new male vanity, in which even Silicon Valley bigwigs considerably younger than Bezos are resorting to newfangled procedures to avoid aging out of the workforce. The stakes have never been higher. American men underwent 1.1 million noninvasive cosmetic procedures in 2018a 72 percent increase since 2000, a trend that shows no signs of abating. In its forecast for 2020, the American Society for Aesthetic Plastic Surgery predicts the continued rise of the Daddy-Do-Over, the male equivalent of the Mommy Makeover, as men look to boost their confidence and improve their physical appearance.

Its a lesson in maintenance the men in the presidential race would do well to learn. In the not so distant past politicians could dismiss reporters questions about whether theyd had a face-lift, as Arnold Schwarzenegger did during his 2003 run for governor of California, when he joked that they must be confusing him with Cher. Now pols and pundits of every party are being grilled as mercilessly about their appearance as about their Medicare plans.

"Unfortunately for Biden, you can see the work thats been done," says one NYC dermatologist.

Joe Bidens forehead and Donald Trumps hair flap and skin color are dissected with the rigor of Kremlinologists (some of them actually are Kremlinologists, in Trumps case). And with good reason: If Hillary Clintons wrinkles, Elizabeth Warrens glasses, and Amy Klobuchars eyebrows are fair game, why not the nipped and tucked peacocks strutting around on Capitol Hill?

Denials about the scars on the side of Bidens face are, according to the experts, malarkey. Unfortunately for Biden, who has obviously had hair transplants and Botox, among other things, you can see the work thats been done, says Wexler. Nobody should be talking about work. When you have work done, the last thing you want is for people to notice it.

The queen of Fraxels laser focus on male primping is not partisan. Mr. Trump has definitely had workand not great work, at that, she adds. Give him his crumb, though: He wasnt bad looking when he was younger and in better shape.

Trumps penchant for cosmetic adjustments has been an open if much denied secret since at least 1991, when Ivana Trump disclosed his scalp reduction surgery and chin and waist liposuction in their divorce papers. In February the world was served a fresh reminder, when the president was photographed, in an image that quickly went viral, stepping out of Marine One with a windswept rug and a fake tan for the history books.

At tony dermatologist practices from coast to coast, man-tans like Trumps and obvious old-school work like the kind favored by Vladimir Putin is frowned uponif anyone can move any facial muscles at all. Instead, next-gen lasers such as NeoSkin by Aerolase, IBeam, and Nd:YAG are used to eliminate redness and discoloration.

Instead of surgical face-lifts, which, to be fair, remain popular in certain parts of the country (I definitely see them more on the West Coast, Wexler says, where its been around longer and is more accepted), men of means are turning to noninvasive procedures, most notably Ultherapy, a relatively painless FDA-cleared ultrasound treatment that requires no downtime.

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For the ultimate injection of masculine vigor, though, Cheung works with membersand not necessarily of Congress. We make penises bigger and better, she says. Self-confidence for men is tied up with their penises and how well they work. We give them their swagger back.

Men looking for an extra glide in their stride are considering the augmented Priapus Shot, or P-shot, Cheung says, a treatment thats the male equivalent of the O-shot. She is also increasingly recommending a machine called Emsella, better known as the Orgasm Throne, which generates approximately 11,000 Kegel contractions in 30 minutes (it was originally developed for female incontinence). It really gives you an invigorating kick in the pants, Cheung says.

If the recent past is anything to go by, theres no guarantee that the candidates who end up squaring off in November will provide anything resembling accurate medical recordswhich is a shame, as they would make interesting reading. Like Bezos and less heralded moguls across the country, they are unlikely to reveal any touch-ups to anyone but their best pals.

Men will come in and ask for something their friend has had done, Wexler says. But you wont hear anyone on Jimmy Fallon saying, Im so tired: I was at the dermatologist all day.

This story appears in the May 2020 issue of Town & Country.

Read more:
Jeff Bezos and the New Face of Male Vanity - TownandCountrymag.com

Recommendation and review posted by Bethany Smith

The author, a government affairs analyst for the National Marrow Donor Program, grew up in Omaha.

Flying during a pandemic is a slightly different experience from flying during normal periods.

Social distancing, for example, is really easy because hardly anyone is in the airports.

I work in Minneapolis for the National Marrow Donor Program and Be The Match, the nations largest bone marrow registry. Im among the 400-plus people who serve as couriers for Be The Match. Couriers transport donated bone marrow or blood stem cells in coolers on commercial flights, taking it from the location where the donation occurred to the hospital where it will be given to a patient.

This week, I traveled from my home in Minneapolis Be The Matchs headquarters city to a city on the East Coast, where I picked up donated blood stem cells. I then took the stem cells to a city on the West Coast, where the patient is.

I cant say the specific cities involved in order to maintain confidentiality of the donor and the recipient.

Couriers are able to travel during this time because we are considered essential critical public health workers.

When I went to pick up the empty cooler before I flew out, a logistics coordinator told me that flights were being canceled left and right and that they were working long hours and on weekends to make sure couriers can continue to travel.

The airports I traveled through were pretty empty no lines to get through security. After the security check, physical distancing wasnt a problem; you could have an entire gate to yourself.

Most stores in the airports were closed, with only a couple of convenience stores still open and takeout-only food options available at restaurants. All the restaurants eating areas were roped off.

Before boarding, airline staff reminded travelers over the intercoms that crews were sanitizing the planes. They also noted that the planes have high-quality air filtration systems.

The usual boarding process by groups (people needing assistance, military members, first class, Group A, etc.) was unnecessary. Gate agents didnt need to go through their normal spiel.

Since we have a very light flight, Im not going through alphabet soup, so all groups are boarding, one gate agent said.

We have plenty of places for bags, so I dont have to ask about that ...

... Do I have any active-duty military?

Pause.

... Do I have anyone whos just happy the day is Monday? OK. Come on down.

Overall, I was lucky in terms of flights. I had three legs of travel: a flight from Minneapolis with a layover to the East Coast, a flight with a layover to the West Coast and a direct flight back to Minneapolis. One of my flights was canceled, one was changed from a direct flight to an indirect route and one was delayed. A team at Be The Match monitors courier travel, so I didnt have to rebook anything myself.

When I called to double-check on one of my flights, the coordinator told me that my experience wasnt bad at all compared with those of other couriers, who have dealt with multiple cancellations and have required several backup itineraries.

My flights had anywhere from 10 to 30 people. I never sat next to anyone else, although passengers sat directly in front of me or across the aisle in the same row. Flight attendants didnt serve drinks in cups with ice, but you could get bottles of water or cans of soda and snacks. I tried to keep my cloth mask on my face for all my flights, taking it off only for an occasional sip of water.

Mask use was sporadic both by airline and airport employees and passengers. On only one flight were attendants wearing masks and eye shields the entire time. I was a little surprised by this and felt that more people should be wearing some sort of protective gear, especially in light of the recent guidance from the Centers for Disease Control and Prevention to wear cloth face coverings in public.

I stayed in two different hotels. At one, I had to sign a document indicating that I was an essential worker, which was pushed to me under a plastic screen. At the other hotel, I checked in behind a retractable barrier about three feet from the desk.

For food, I ordered takeout, paid online and picked up a couple times, but mostly I stayed in my room and ate the food I packed. I wanted a latte but just drank the coffee from the little machine in my hotel room. It seemed weird to order online just for coffee.

My parents werent thrilled that I was traveling across the country right now, but I know that patients cant wait for the pandemic to be over to get the transplant they need its life or death for them. And lots of couriers are traveling: In March, for example, Be The Match facilitated 604 transplants.

As more and more travel restrictions are put in place, Be The Match may have to rely on other transportation, such as military transport. But for now, Im looking to see when I can take the next trip.

I should note that the delivery to the hospital went smoothly. Thats always a relief. Its all possible because of the donors, lab staff, doctors, nurses and other transplant center workers and my Be The Match coworkers.

To find out how to become a bone marrow donor, visit bethematch.org/support-the-cause/donate-bone-marrow/join-the-marrow-registry/.

Hank, a Labrador retriever, does not respect social distancing and gives Morgan Henderson, the owner of Dirty Doodles, a kiss while being groomed at Dirty Doodles in Omaha. The dog grooming service has moved work stations outside so employees can remain six feet apart during the novel coronavirus pandemic.

A message written in chalk on a wall along Martha Street in Omaha on Wednesday, April 8, 2020.

Traffic is sparse at time on Interstate 80 through Omaha as people are encouraged to stay home amid the coronavirus pandemic.

Handwritten notes for customers at Nite Owl in Omaha on Wednesday, April 1, 2020. Nite Owl has been writing personal notes to customers and offering specials, like the Social Distance Daiquiri, while offering curbside take-out as the novel coronavirus pandemic continues.

Karna Gurung answers a text on his phone at his store located at 822 N 40th Street on Thursday, April 02, 2020. Gurung is translating important information about coronavirus for non english speaking members of his community.

Rita Otis leads an outdoor Tai Chi class on a grass island at Glenwood Road and Sunset Trail on Wednesday, April 01, 2020. Participants had to maintain a distance of six feet due to coronavirus social distancing measures.

Rita Otis leads an outdoor Tai Chi class on a grass island at Glenwood Road and Sunset Trail on Wednesday, April 01, 2020. Participants had to maintain a distance of six feet due to coronavirus social distancing measures.

The Easter Bunny waves to families as they drive by at the Hy-Vee near 144th and Stony Brook Blvd. in Omaha on Saturday, April 4, 2020. The grocery store usually hosts an Easter egg hunt, but went with a drive-thru Easter Bunny visit this year to encourage social distancing in response to the novel coronavirus.

A sign is installed at Zorinsky Lake Park in Omaha on Saturday, April 4, 2020. Playgrounds and athletic fields are closed in all Omaha parks.

A ball field is seen through a chainlink fence, at Lee Valley Park in Omaha on Saturday, April 4, 2020. Playgrounds and athletic fields are closed in all Omaha parks.

A ball field sets empty at Prairie Lane Park in Omaha on Saturday, April 04, 2020. Playgrounds and athletic fields are closed in all Omaha parks.

A Washington Elementary School sign reads 'Nebraska Strong' on Thursday, April 02, 2020, in Fremont, Nebraska.

About 100 people line up outside Brickway Brewery & Distillery in Omaha on Monday, April 6, 2020. The Old Market business was giving away free hand sanitizer on tap to anyone who brings their own bottle of 64 ounces or less.

Don Rupp wears a face mask made by his wife while waiting in line outside Brickway Brewery & Distillery in Omaha on Monday, April 6, 2020. The Old Market business was giving away free hand sanitizer on tap to anyone who brings their own bottle of 64 ounces or less.

The empty streets of downtown Grand Island on Monday, April 06, 2020. The area was experiencing a surge in coronavirus cases.

Playground equipment is seen wrapped in caution tape at Pier Park on Monday, April 06, 2020, in Grand Island, Nebraska. Playgrounds are closed as a measure to prevent the spread of coronavirus.

Russell Hatt smokes a cigarette outside of Fonner Park at on Monday, April 06, 2020, in Grand Island, Nebraska. "I'm a widower, so this is what I do to stay busy. I bet on horses and play Texas Hold'em."

The Kroc Center is illuminated as a symbol of hope in Omaha on Monday, April 6, 2020.

Rabbi Daniel Blotner puts together Seder-To-Go kits at Chabad House in Omaha on Monday, April 6, 2020. The Seder is a ritual dinner to mark the beginning of Passover, which began on April 8. The free kits and were available for delivery for anyone who is homebound during the novel coronavirus pandemic.

Leah Hanson and others visit their grandmother from outside the Douglas County Health Center in Omaha on Tuesday, April 7, 2020.

From left, Carol Ann Hixson, Terri Rohmeyer and Carol Carol Coffey wave and blow kisses to a family member from outside the Douglas County Health Center in Omaha on Tuesday, April 7, 2020.

A woman walks a dog as the sun sets on Elmwood Park in Omaha on Wednesday, April 08, 2020. Omaha has closed all city parks until April 30 to combat COVID-19. The trail system will remain open, but parking lots at trail heads are closed. People must walk or bike in.

A couple walks along the West Papio Trail in Omaha on Wednesday, April 08, 2020. Omaha has closed all city parks until April 30 to combat COVID-19. The trail system will remain open, but parking lots at trail heads are closed. People must walk or bike in.

Kennedy Cascio has decorated her home's front door with a symbol for medicine and hearts. Cascio is an intensive care unit nurse at the Bellevue Medical Center and created the display to "show that I am thankful for everyone working on the frontlines," as the novel coronavirus pandemic continues. Photographed in Omaha on Wednesday, April 8, 2020.

A message is left along a fence at Lewis and Calrk Middle School in Omaha on Thursday, April 09, 2020. Omaha Public Schools have been closed since mid-March, with remote learning for all students, as the novel coronavirus pandemic continues.

Traffic signs on Dodge Street, near 168th, display self quarantine guideline suggestions on Monday, April 06, 2020.

A sparrow sit in its nest in the letter "g" in Walgreens sign at 5038 Center Street on Friday, April 10, 2020.

Originally posted here:
Few folks are flying during the coronavirus outbreak, former Omahan finds - Omaha World-Herald

Recommendation and review posted by Bethany Smith

Contraryto previous research, some patients with atopy who undergo allogeneichematopoietic cell transplantation (AHCT) may be cured even if the donor isatopic, according to research published in Bone Marrow Transplantation.

Investigatorsaimed to determine whether atopic disease could be cured or transferred fromdonor to recipient, as there is evidence, though unconfirmed, that AHCT caneither transfer atopy from donor to recipient when the donor has the conditionand the recipient does not (D+R-), or cure atopy in a recipient with thecondition when the donor does not have it (D-R+).

Of the 54 participants including in the study, the median age at transplant was 46 years (range, 4-64 years), one-third of patients had acute myeloid leukemia, and 50% had a human leukocyte antigenmatched sibling. The median donor age at transplant was 34 years (range, 7-60 years).

Amongall AHCT procedures included in this study, 18 (33%) had an atopic donor andrecipient (D+R+), 13 (24%) had a nonatopic donor and recipient (D-R-), 11(20.4%) had an atopic donor and nonatopic recipient, and 12 (22.2%) had anonatopic donor and an atopic recipient.

At afollow-up of at least 2-years post-HCT, 7 of 12 (58%) D-R+ patients becamenonatopic, while only 1 of 11 (9%) D+R- patients became atopic. While 11 of 13(85%) D-R- patients remained nonatopic, 11 of 18 (61%) D+R+ patients became nonatopic,as well.

Inconclusion, cure of atopy with HCT occurs in about half patients, albeitprobably not due to the replacement of atopic with nonatopic immune system butpossibly due to an immune reset analogous to that observed in some autoimmunedisease patients after autologous HCT, the authors concluded. They added thatprospective trials are needed to confirm these findings.

Reference

Whiteside S, Chin A, Tripathi G, et al. Curtability and transferability of atopy with allogeneic hematopoietic cell transplantation [published online March 30, 2020]. Bone Marrow Transplant. doi: 10.1038/s41409-020-0876-7

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Atopy: Weighing Risk With the Possibility of Cure Using Hematopoietic Cell Transplantation - Hematology Advisor

Recommendation and review posted by Bethany Smith

By Jessica Lake

Updated April 12, 2020 08:32:52

Almost two years ago, our world fell apart.

Our cheeky and sweet three-year-old son Larry suddenly became unwell. His previously robust physicality waned. His ruddy complexion became creamy.

His rosy cheeks and rose red lips glowed a pale pink at best. There were bad bruises on his legs darker and deeper ones than those dotting the knees of his identical twin brother. There was a strange patch of little red dots on his neck petechia, we would later learn pin-prick bleeding under the skin.

We took him to our GP. Then we took him to Monash Children's Emergency. Then, a few weeks later, we arrived at the Children's Cancer Centre of the Royal Children's Hospital.

He was diagnosed with idiopathic very severe aplastic anaemia. For unexplained reasons, his bone marrow had spontaneously started shutting down. We were disoriented and devastated.

Without the ability to make blood, Larry required constant transfusions. Every six-to-10 days, when his nose oozed or a blood blister appeared in his mouth, we would race to the clinic or emergency department (sometimes via ambulance) for a bag of platelets: "yellow medicine" our son called it. Once he could clot again we could relax a little.

About every one-to-three weeks, when he struggled to pull himself out of bed or off the couch, when his appetite diminished and his pallor grew too pale, he would receive a bag of "red medicine" to resuscitate his system.

Until mid 2018, I had the privilege and luck of never thinking much about blood donation. But now, the prospect of a shortage terrifies me.

Due to COVID-19, the Australian Red Cross Lifeblood service faces a critical shortage unless thousands of people donate.

Over a period of 14 months, while our son battled bravely through immunosuppressive treatment and multiple infections, he underwent more than 70 platelet transfusions and 40 blood transfusions. The blood of more than 100 kind souls kept him going.

One day last April, Larry's haemoglobin was the lowest it had ever been. In the 50s. Less than half the level of a "normal" person.

It was a Saturday morning, and I'd just raced him through city traffic to the hospital emergency department yet again.

Once we arrived, they ordered a bag of red cells. He dozed on the trolley bed. His lips the same colour as his skin. His skin the same colour as the sheet he had just vomited on.

I fidgeted and hopped back and forth around the doorway of our cubicle watching for the blood bank delivery. Please. Please. Please. An agonising wait. Finally, it arrived.

A rush of immense gratitude. The nurses did their double cross checks. Name, date of birth, patient number. Then it was hooked up to the IV Pump and connected. 235 millilitres over four hours.

I stared at the bag: "Collected 15 April 2019, due to expire 15 May 2019". I wondered who donated it on that Monday two weeks before. A man or a woman? Young or old? Which centre had they attended? Had they congratulated or rewarded themselves for their gift? I hoped so.

After 20 minutes, my dear little boy started to stir. He'd only had 19ml by then but it was already making a difference. A dusky warm colour was creeping into his complexion. Energy was reaching his cells again. By the time one hour had passed, he was sitting up, demanding food, drawing, playing I-spy and cracking jokes.

I assume if everyone could witness this miraculous transformation, we would all run to the blood bank and offer up our veins. By the end of the day, the bag of blood was empty and Larry was full of life again temporarily.

In August 2019, our son underwent a long-awaited bone marrow transplant.

From a pool of more than 30 million bone marrow donors worldwide, only three were a match, all from overseas.

Someone in Europe willingly, with no financial incentive or reward, booked into their local hospital and had stem cells sucked from their hip bones so that a stranger our son might live. An amazing act of generosity.

The sludgy burgundy bag arrived in Melbourne late at night on a commercial flight. Our little Larry had already undergone seven days of heavy chemotherapy in order to be ready to receive the cells. The last scraps of his immune system had been destroyed to make necessary space.

It was either the beginning, or the end of the road.

After a couple of months in isolation, Larry was discharged from hospital. A new beginning.

He is now six months post-transplant and doing well. He plays riotously with his twin brother and big sister. He no longer needs blood. He can make his own again, for now.

But many children at the Children's Cancer Centre cannot. They rely on platelets, plasma and blood to survive day-to-day. A shortage spells disaster.

Many are also relying on a bone marrow transplant for an ultimate cure. And due to travel bans and overwhelmed hospital systems globally, overseas bone marrow donors are now inaccessible indefinitely.

It is painful to imagine Larry's plight if the coronavirus occurred a year earlier.

Let's honour the tremendous courage of kids like Larry by showing ours. Make an appointment at Australia Red Cross Lifeblood today.

Give blood. Give your name to the bone marrow register. Give laughter, hope and life to these incredible kids.

Let's not let cancer treatment become another casualty of the coronavirus crisis.

Jessica Lake is a mother, writer, academic, and member of the Parent's Advisory Group of the Children's Cancer Centre at the Royal Children's Hospital, Melbourne.

Topics:covid-19,diseases-and-disorders,health,blood,children,family-and-children,community-and-society,melbourne-3000,australia

First posted April 12, 2020 05:00:59

Here is the original post:
My son needed regular blood transfusions, but now coronavirus threatens the survival of children like him - ABC News

Recommendation and review posted by Bethany Smith