New technique to decellularize tissues for tissue engineering and regenerative medicine
New technique to decellularize tissues for tissue engineering and regenerative medicine. Subscribe this channel to watch more motivational, inspirational, va...

By: Health Mind Body Spirit

See more here:
New technique to decellularize tissues for tissue engineering and regenerative medicine - Video

Recommendation and review posted by sam

ND|spinal cord injury|13

By: khloody alahmary

Follow this link:
ND|spinal cord injury|13 - Video

Recommendation and review posted by sam

Author: Ian Murnaghan BSc (hons), MSc - Updated: 11 September 2014 | Comment

A bone marrow stem cell transplant uses stem cells derived from bone marrow to provide a fresh and healthy source of new blood cells which in turn, allows for a patient to receive higher doses of chemotherapy to treat certain types of cancer such as leukaemia. This ultimately means that a person has a better chance of surviving cancer. The bone marrow stem cells may be allogeneic and therefore donated by a family member of stranger, or they may be autologous, which utilizes a patient's own stem cells.

Bone marrow stem cells are found in bone marrow and in a person's blood. After stem cells multiply, they form immature blood cells, which are then subject to a collection of changes that allow them to develop into mature blood cells. Once mature, the blood cells migrate from the marrow and are introduced into the bloodstream, where they provide important functions in keeping the body alive and healthy.

A patient will usually receive some chemotherapy to reduce cancer cells before stem cells are collected. The harvested stem cells are also treated to ensure that no cancer cells remain. Higher doses of chemotherapy are then given, sometimes alongside complete body radiation, to confirm that no cancer remains. Stem cells are then transplanted back into the body via a rapid injection. Stem cells will eventually migrate to the bone marrow, where they latch onto other cells there and develop into the different blood cells.

Stem cells are then infused into the patient via an intravenous line over several hours. Stem cells travel to the patient's bone marrow where they develop and produce the blood cells necessary for blood functioning. Patients may also still be given drug therapy for some time to reduce the chances of immune rejection.

Bone marrow stem cell harvests are clearly a life saving technique for those suffering from certain cancers such as leukaemia. They are one of the 'older' stem cell therapies and have been proven effective for decades now. There are, however, still issues of rejection that warrant further development and refinement of stem cell harvesting techniques. It is hoped that scientists will continue to focus on research to improve the odds of success for this important treatment.

You might also like...

Leave a Comment, Ask for Advice or Share Your Story...

Sohaila Reda - 9-Aug-14 @ 5:06 PM

See the article here:
Bone Marrow Stem Cell Harvest

Recommendation and review posted by Bethany Smith

November 29, 2014

"Spider silk' is stronger than conventional silk and could be used for textiles

TOKYO: Japanese scientists have developed through genetic engineering using genes from spiders and silkworms a super resistant silk which could be used for textiles as well as in the surgical field, media reported on Friday.

Known as Spider Silk, which is stronger and smoother than conventional silk, it has been developed by researchers at Shinshu University, the Asahi daily newspaper reported.

Masao Nakagaki from the Faculty of Textile Science and Technology was the first person, in 2007, to implant spider genes in silkworms, resulting in the production of silk which had some components of spider webs.

Several years of research has now led to the development of spider silk which has less than 20 per cent of the components of spider webs.

Several prototypes of socks have also been manufactured using this new material.

It is expected that the hybrid silk would be used in the textile industry, and for manufacturing surgical threads and artificial blood vessels.

The university reached an agreement with the local government to commercially produced the hybrid silk.

Both institutions have decided to collaborate in areas of industrial development, training of personnel, academic research and use of facilities for commercial production of the silk, according to Asahi.

Visit link:
Scientists develop hybrid silk using spider genes

Recommendation and review posted by Bethany Smith

A gene therapy spinout from Childrens Hospital of Philadelphia has added a head of regulatory affairs as it continues Phase 3 clinical trials for its treatment to reverse the effects of inherited retinal degeneration caused by a mutation in the RPE65 gene. It is the latest in a series of additions to the company following a $72.8 million Series B fundraise earlier this year.

Daniel Takefman previously worked for eight years as chief of the gene therapy branch at the Center for Biologics Evaluation and Research at the U.S. Food and Drug Administration, according to a company statement.

Spark Therapeutics, headed by CEO Jeffrey Marrazzo, has been bulking up its management muscle this year. Dr. Katherine High, the former founding director of the Center for Cellular and Molecular Therapeutics at CHOP and a pediatrician at the Perelman School of Medicine, became president and Chief Scientific Officer and has a board seat. It added Stephen Webster as CFO from Optimer Pharmaceuticals and Adolor Corp, whic Cubist Pharmaceuticals acquired in 2011. Steven Gelone joined as head of clinical research and development. Gelone had previously worked for ViroPharma in a similar role Shire acquired the company last year. Diane Blumenthal, another industry veteran, became head of technical operations. She had worked for Eli Lilly for 14 years.

Romuald Corbau, former research project leader for Pfizers gene therapy program for the hepatitis C virus, joined as Sparks translational research lead to help support the companys pipeline of gene therapies.

Earlier this month Spark received breakthrough therapy designation for its SPK-RPE65 treatment. The status speeds up the development and review of investigational therapies for serious or life-threatening conditions, particularly when theres an unmet need.

Marrazzo said earlier this year that the company expects to have data from the Phase 3 trial available in the first half of 2015. In addition to its lead indication, Spark is also working on a Hemophilia B gene therapy treatment to reduce the doses of clotting factor that hemophiliacs need to take to avoid excessive bleeding. The condition is estimated to affect 20,000 people, according to the Centers for Disease Control.

[Photo credit: BigStock Photos]

Get our daily newsletter or follow us.

Please enter your email below:

More:
Spark Therapeutics adds regulatory insider to support gene therapy for retinal degeneration

Recommendation and review posted by Bethany Smith

Global Cell Expansion Market Research Report 2019
New Market Research Report on Cell Expansion Market by Product (Reagent, Media, Serum, Bioreactors, Centrifuge), Cell Type (human, animal), Application (Stem Cell Research, Regenerative...

By: David clark

Read this article:
Global Cell Expansion Market Research Report 2019 - Video

Recommendation and review posted by sam

Stem Cell Therapy Project
Daniel, John, Magno, Thahn, Victor, Vivian show the world just exactly what stem cells really are.

By: John Peterman

See more here:
Stem Cell Therapy Project - Video

Recommendation and review posted by simmons

Stem Cell Therapy - BioLogic Anti-Aging Skin Cream
http://www.ReadTheReviewsFirst.com Truvisage Anti-Aging Skin Care International Is Better Than Botox!

By: Greg Smith

View original post here:
Stem Cell Therapy - BioLogic Anti-Aging Skin Cream - Video

Recommendation and review posted by simmons

Stem Cell Therapy Anti Aging Skin Cream Review and Exclusive Deal
http://www.ReadTheReviewsFirst.com Truvisage Anti-Aging Skin Care International Is Better Than Botox!

By: Greg Smith

Follow this link:
Stem Cell Therapy Anti Aging Skin Cream Review and Exclusive Deal - Video

Recommendation and review posted by simmons

Cell Therapy Limited on Crowdcube - Repairing Broken Hearts
HeartcelTM is a novel stem cell therapy that can regenerate the heart following heart failure - a Cell Therapy Ltd Medicine.

By: Cell Therapy Ltd

The rest is here:
Cell Therapy Limited on Crowdcube - Repairing Broken Hearts - Video

Recommendation and review posted by simmons

Stem Cell Therapy to Treat Equine Tendon Injuries
A brief explanation of tendon injuries and how stem cell therapy can be used to treat them.

By: Animal Science

Read the original here:
Stem Cell Therapy to Treat Equine Tendon Injuries - Video

Recommendation and review posted by simmons

Stem Cells Enhancement Naturally!
How to Enhance Your Bone Marrow Stem Cells.

By: Dave W Easter

Read more here:
Stem Cells Enhancement Naturally! - Video

Recommendation and review posted by Bethany Smith

CBS New York (con't)

Affordable Care Act Updates: CBSNewYork.com/ACA

Health News & Information: CBSNewYork.com/Health

NEW YORK (CBSNewYork) A New York woman battling leukemia was especially grateful this Thanksgiving, as she credited the kindness of a total stranger with helping save her life.

They found the donor, and it was just basically like a weight lifted off my shoulders, said Jeanine Walsh, 38.

As CBS2s Dr. Max Gomez reported Thursday, Walsh the mother of two young children has been battling leukemia for the second time in two years.

I was in total and complete shock, she said.

No members of Walshs family were a match for her, but a willing donor was found through the national registry. Peripheral stem cells were collected from the donor, located in the Western U.S., earlier this week.

The process took just a few hours.

We attach the patient, that is the donor, to a machine. The machine takes blood form the donor, filters out the stem cells if you will, and returns the rest of the blood to the donor, said Dr. Michael Schuster, director of stem cell transplantation at Stony Brook University Hospital.

Originally posted here:
Stranger Donates Stem Cells In Hopes Of Curing New York Woman With Leukemia

Recommendation and review posted by Bethany Smith

Islam, Genetic Engineering and Bioethics /
Interview with Dr. Rana Dajani.

By: TVIslamScience

See the rest here:
Islam, Genetic Engineering and Bioethics / - Video

Recommendation and review posted by Bethany Smith

Get To Know A Scientist: Featuring longevity and genetics experts Aubrey de Grey and Cosmo Mielke
Interview featuring ground breaking longevity, genetics, and aging researchers, Aubrey de Grey and Cosmo Mielke. Video shot a SFU Segel building at 500 Granv...

By: Steve Nygaard

Read the original here:
Get To Know A Scientist: Featuring longevity and genetics experts Aubrey de Grey and Cosmo Mielke - Video

Recommendation and review posted by Bethany Smith

Science Today: Genetics of Monarch Migration | California Academy of Sciences
The epic journey monarch butterflies make is reflected in their genes.

By: California Academy of Sciences

Go here to read the rest:
Science Today: Genetics of Monarch Migration | California Academy of Sciences - Video

Recommendation and review posted by Bethany Smith

Norbreck Genetics Autumn Update
Norbreck Genetics Autumn Update.

By: Marcus Pomfret

Continue reading here:
Norbreck Genetics Autumn Update - Video

Recommendation and review posted by Bethany Smith

Susan Doak

SW Nebraska

Genealogy Society

McCOOK, Neb. -- My cousin received her results from taking the Ancestry.com DNA test and she sent me her results to see how I interpreted them. My first response back to her was that the scope of her Germanic ancestry was so vast that even though we are first cousins, I have a feeling my results would be remarkably different except for the fact that her results show a 99% European heritage.

The first thing that does is eliminate all of the "family rumors" concerning our great-great grandmother being a Native American. The smallest listed ancestry for my cousin was 1% Finnish. Even if our grandmother was only an eighth Native, my cousin would have a greater than 1% Native Heritage which would have been reflected in her results.

The second thing it has eliminated was my theory that our third great-grandmother was perhaps one of the many mixed heritage indentured servants or slaves who escaped into Kentucky and then hid her true heritage by marrying "white." The term for that was "passing," meaning the light color of the escapee's skin gave them access to a lifestyle forbidden by law for African Americans at that time. Again, this test would have shown a greater than 1% heritage from Africa if true.

It's good to know these two answers because it will eliminate any further venturing down those very difficult-to-trace linages. I'm not sure it's going to make finding more information any easier but it does point me in a different direction.

The only reason that I can even make these assumptions considering that my cousin and I are female children of a brother and sister is because the test that she submitted was autosomal (non-gender specific) and the resulting matches will cover both the maternal and paternal sides of a family all inclusively (siblings, parents, aunts, uncles, cousins, grandparents, etc.) for the past few generations or as Ancestry.com states: "Genealogically relevant time periods."

For me, that is an important statement. Y-DNA tests look specifically at your direct paternal lines: Father to father to father and so on. If female, you must have a living father, brother, paternal grandfather, etc., to take the test for you. A male cousin's results would take an alternate path to connect your tree.

On the other hand, mtDNA, which both men and women can have done, looks at only your direct Maternal Lineage: Mother to mother to mother. A mother passes her mtDNA to all her children, but only her daughters pass it on to their children. If you are interested in your maternal ancient history -- the migration pattern of your maternal ancestors -- this test will give you those answers, but it will not be as generation specific as an autosomal or even an YDNA test.

Read more:
Genetics and genealogy

Recommendation and review posted by Bethany Smith

#NotImmune - Alliance for Cancer Gene Therapy
Alliance for Cancer Gene Therapy funds research to: Attack the cancer, not the patient. http://www.acgtfoundation.org/notimmune ACGT is the nation #39;s only nonprofit ...

By: ACGTFoundation

See the rest here:
#NotImmune - Alliance for Cancer Gene Therapy - Video

Recommendation and review posted by Bethany Smith

Personalized Medicine and Mental Health | Don Wright | TEDxCincinnati
This talk was given at a local TEDx event, produced independently of the TED Conferences. Millions of Americans take antidepressant medications but they only...

By: TEDx Talks

More here:
Personalized Medicine and Mental Health | Don Wright | TEDxCincinnati - Video

Recommendation and review posted by sam

JSB Market Research : Personalized Medicine and Companion Diagnostic Market
Personalized Medicine and Companion Diagnostic Market - A Strategic Analysis of Industry Trends, Technologies, Participants, and Environment is a cutting-e...

By: richa patel

More:
JSB Market Research : Personalized Medicine and Companion Diagnostic Market - Video

Recommendation and review posted by sam

OncoPedia the First Show of the Regular Oncology Weekly Hangout
Marco Andre Costa MD, a Head and Neck Cancer Doctor from Sao Paulo, Brazil leads a discussion on the state of Lung Cancer prognosis and treatment. Covered are topics such as Personalized ...

By: John Bennett

Visit link:
OncoPedia the First Show of the Regular Oncology Weekly Hangout - Video

Recommendation and review posted by sam

ND|spinal cord injury|10

By: khloody alahmary

Continued here:
ND|spinal cord injury|10 - Video

Recommendation and review posted by sam

Partner Profile: Rick Hansen Institute
Since 2006, the Michael Smith Foundation for Health Research and the Rick Hansen Institute have jointly funded BC researchers whose work is helping to enhance our understanding of spinal cord...

By: MSFHR

See original here:
Partner Profile: Rick Hansen Institute - Video

Recommendation and review posted by sam

ENFIELD When 7-year-old Emma Duffin came down with strep throat last spring, her family never imagined the journey that illness would begin.

When Emma spiked a 104-degree fever, her mother took her to the emergency room at Johnson Memorial Hospital in Stafford Springs.

A doctor noticed Emma had dangerously low red and white blood cell counts, so she was sent to Connecticut Children's Medical Center for more tests. Her hemogobin level, normally a 12, was at 3. She received three pints of blood.

A few days later, a diagnosis: leukemia. A biopsy indicated the disease was located in her bone marrow.

"That was Mother's Day weekend," Allyson Duffin, Emma's mother, said recently. "We cried and then said, 'Now what?' "

Samples of Emma's bone marrow were sent to the Mayo Clinic Cancer Center in Rochester, Minn., Sloan Kettering Cancer Center in New York, and the Dana Farber Cancer Institute in Boston to determine what type of leukemia she had.

It turned out Emma has a rare form of leukemia called acute undifferentiated leukemia that is especially rare in children, according to Dr. Natalie Bezler, Emma's doctor at CCMC. Effects on the cellular level can differ from patient to patient.

"At first I thought cancer was a disease by itself, you just had 'cancer,' " Emma said. "But no, there's different types of cancer."

'Perfect Match'

The summer brought a new set of challenges for the Duffin family.

More here:
Emma's Journey: Brother's Bone Marrow, Positive Attitude Help Enfield Girl Battle Leukemia

Recommendation and review posted by Bethany Smith