Theo #39;s Strain Reviews Lemon Skunk from DNA Genetics
I love this medicine! Great phenotype from a freebie bean, doesn #39;t get much better than that 🙂 Subscribe, Like, Comment, Share!

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How to solve genetics problems using factorials
The factorial of a number is the product of all the whole numbers, except zero, that are less than or equal to that number. For example, to find the factoria...

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Laser Genetics ND1 SubZero Tactical Laser Sight
http://video.sportsmansguide.com/?v=1914080536 Watch this video featuring products from GAMO USA and buy from a large selection on The Sportsmans Guide. - Pr...

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Pathology Topic 03 Genetics
Live MD Entrance Coaching for AIPGMEE 2014 at http://www.onlinembbs.com. Revise 1200 High yield topics for AIIMS PGI AIPGMEE FMGE in 30 weeks . Every day 3 hours cl...

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Pathology Topic 03 Genetics - Video

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Introduction to Population Genetics - Lynn Jorde (2014)
April 9, 2014 - Current Topics in Genome Analysis 2014 A lecture series covering contemporary areas in genomics and bioinformatics. More: http://www.genome.g...

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Mark Hamalainen: Gene Therapy
Mark #39;s talk at Future Friday 04/04/14.

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Mark Hamalainen: Gene Therapy - Video

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CryoDerm Testimonial Spinal Cord Injury
Check out this testimonial about CryoDerm #39;s affects on those with spinal cord injury. Listen to her results and try CryoDerm for yourself! CryoDerm is commit...

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Scientists Transplant Lab-Made Sexual Organs
The quest to make body parts in the lab has just taken a big step forward. Scientists have successfully transplanted laboratory-made vaginas into four teenag...

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Tissue engineering has been used to construct natural oesophagi, which in combination with bone marrow stem cells have been safely and effectively transplanted in rats. The study, published in Nature Communications, shows that the transplanted organs remain patent and display regeneration of nerves, muscles, epithelial cells and blood vessels.

The new method has been developed by researchers at Karolinska Institutet in Sweden, within an international collaboration lead by Professor Paolo Macchiarini. The technique to grow human tissues and organs, so called tissue engineering, has been employed so far to produce urinary bladder, trachea and blood vessels, which have also been used clinically. However, despite several attempts, it has been proven difficult to grow tissue to replace a damaged esophagus.

In this new study, the researchers created the bioengineered organs by using oesophagi from rats and removing all the cells. With the cells gone, a scaffold remains in which the structure as well as mechanical and chemical properties of the organ are preserved. The produced scaffolds were then reseeded with cells from the bone marrow. The adhering cells have low immunogenicity which minimizes the risk of immune reaction and graft rejection and also eliminates the need for immunosuppressive drugs. The cells adhered to the biological scaffold and started to show organ-specific characteristics within three weeks.

The cultured tissues were used to replace segments of the esophagus in rats. All rats survived and after two weeks the researchers found indications of the major components in the regenerated graft: epithelium, muscle cells, blood vessels and nerves.

"We believe that these very promising findings represent major advances towards the clinical translation of tissue engineered esophagi," says Paolo Macchiarini, Director of Advanced center for translational regenerative medicine (ACTREM) at Karolinska Institutet.

Tissue engineered organs could improve survival and quality of life for the hundreds of thousands of patients yearly diagnosed with esophageal disorders such as cancer, congenital anomalies or trauma. Today the patients' own intestine or stomach is used for esophageal replacements, but satisfactory function rarely achieved. Cultured tissue might eliminate this current need and likely improve surgery-related mortality, morbidity and functional outcome.

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Regenerated esophagus transplanted in rats

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Advanced Cell Technology is testing a stem-cell treatment for blindness that could preserve vision and potentially reverse vision loss.

Vision support: The cells used in Advanced Cell Technologys clinical trials produce dark pigments and cobblestone-like patterns that can be readily recognized in cultures.

A new treatment for macular degeneration is close to the next stage of human testinga noteworthy event not just for the millions of patients it could help, but for its potential to become the first therapy based on embryonic stem cells.

This year, the Boston-area company Advanced Cell Technology plans to move its stem-cell treatment for two forms of vision loss into advanced human trials. The company has already reported that the treatment is safe (see Eye Study Is a Small but Crucial Advance for Stem-Cell Therapy), although a full report of the results from the early, safety-focused testing has yet to be published. The planned trials will test whether it is effective. The treatment will be tested both on patients with Stargardts disease (an inherited form of progressive vision loss that can affect children) and on those with age-related macular degeneration, the leading cause of vision loss among people 65 and older.

The treatment is based on retinal pigment epithelium (RPE) cells that have been grown from embryonic stem cells. A surgeon injects 150 microliters of RPE cellsroughly the amount of liquid in three raindropsunder a patients retina, which is temporarily detached for the procedure. RPE cells support the retinas photoreceptors, which are the cells that detect incoming light and pass the information on to the brain.

Although complete data from the trials of ACTs treatments have yet to be published, the company has reported impressive results with one patient, who recovered vision after being deemed legally blind. Now the company plans to publish the data from two clinical trials taking place in the U.S. and the E.U. in a peer-reviewed academic journal. Each of these early-stage trials includes 12 patients affected by either macular degeneration or Stargardts disease.

The more advanced trials will have dozens of participants, says ACTs head of clinical development, Eddy Anglade. If proved safe and effective, the cellular therapy could preserve the vision of millions affected by age-related macular degeneration. By 2020, as the population ages, nearly 200 million people worldwide will have the disease, estimate researchers. Currently, there are no treatments available for the most common form, dry age-related macular degeneration.

ACTs experimental treatment has its origins in a chance discovery that Irina Klimanskaya, the companys director of stem-cell biology, made while working with embryonic stem cells at Harvard University. These cells have the power to develop into any cell type, and in culture they often change on their own. A neuron here, a fat cell thereindividual cells in a dish tend to take random walks down various developmental paths. By supplying the cultures with fresh nutrients but otherwise leaving them to their own devices for several weeks, Klimanskaya discovered that the stem cells often developed into darkly pigmented cells that grew in a cobblestone-like pattern. She suspected that they were developing into RPE cells, and molecular tests backed her up.

Now that her discovery has advanced into an experimental treatment, Klimanskaya says she is excited by the hints that it may be able to preserve, and perhaps restore, sight. She recalls a voice mail she received during her second year at ACT: a person blinded by an inherited condition thanked her for her work, whether or not there was a treatment available for him. When you get a message like this, you feel like you are not doing it in vain, she says.

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Stem-Cell Treatment for Blindness Moving Through Patient Testing

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MONDAY, April 14, 2014 (HealthDay News) -- A new study found that 10 percent of women with a personal or family history of breast or other cancers had at least one gene mutation that would lead their doctors to recommend changes in their routine care, including increased cancer screening.

These women did not have BRCA1 or BRCA2 mutations that are strongly associated with hereditary breast and ovarian cancer. However, they had mutations in other genes known to be linked with cancer, the Stanford University School of Medicine team said.

For the study, the researchers used what is called a multiple-gene panel -- rather than whole genome sequencing -- to sequence specific genes more quickly and cheaply. Whole genome sequencing is a laboratory process that involves "reading" all the characteristics of your DNA.

"Although whole-genome sequencing can clearly be useful under the right conditions, it may be premature to consider doing on everyone," study senior author Dr. James Ford, director of Stanford's clinical cancer genetics program, said in a university news release.

The researchers analyzed blood samples collected from 198 women who were part of the clinical cancer genetics program between 2002 and 2012. Of those women, 57 had BRCA1/BRCA2 mutations and 14 had mutations in 42 other genes associated with cancer.

Of those 14 women, 11 could be reached by telephone and 10 of them agreed to a follow-up appointment with a genetic counselor and a cancer specialist to discuss their test results. One woman had died since giving her blood sample, but her family members also accepted counseling.

Six of the women were advised to have annual breast MRIs and six were told to have regular screenings for gastrointestinal cancers. Some of the women were given more than one recommendation, according to the study published April 14 in the Journal of Clinical Oncology.

"Gene panels offer a middle ground between sequencing just a single gene like BRCA1 that we are certain is involved in disease risk, and sequencing every gene in the genome," said Ford, an associate professor of medicine and of genetics. "It's a focused approach that should allow us to capture the most relevant information."

However, more research is needed before gene-panel screenings could become routine, the researchers said.

-- Robert Preidt

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Cheaper 'Gene Panel' Screening May Reveal Cancer Risks

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University of Missouri researchers have previously shown that a genetic pre-disposition to be more or less motivated to exercise exists. In a new study, Frank Booth, a professor in the MU College of Veterinary Medicine, has found a potential link between the genetic pre-disposition for high levels of exercise motivation and the speed at which mental maturation occurs.

For his study, Booth selectively bred rats that exhibited traits of either extreme activity or extreme laziness. Booth then put the rats in cages with running wheels and measured how much each rat willingly ran on their wheels during a six-day period. He then bred the top 26 runners with each other and bred the 26 rats that ran the least with each other. They repeated this process through 10 generations and found that the line of running rats chose to run 10 times more than the line of "lazy" rats.

Booth studied the brains of the rats and found much higher levels of neural maturation in the brains of the active rats than in the brains of the lazy rats.

"We looked at the part of the brain known as the 'grand central station,' or the hub where the brain is constantly sending and receiving signals," Booth said. "We found a big difference between the amount of molecules present in the brains of active rats compared to the brains of lazy rats. This suggests that the active rats were experiencing faster development of neural pathways than the lazy rats."

Booth says these findings may suggest a link between the genes responsible for exercise motivation and the genes responsible for mental development. He also says this research hints that exercising at a young age could help develop more neural pathways for motivation to be physically active.

"This study illustrates a potentially important link between exercise and the development of these neural pathways," Booth said. "Ultimately, this could show the benefits of exercise for mental development in humans, especially young children with constantly growing brains."

Booth's study, "Nucleus accumbens neuronal maturation differences in young rats bred for low versus high voluntary running behavior," was published in the Journal of Physiology.

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Attack of the Bteam Mod Tutorials - Advanced Genetics
Advanced Genetics is a mod created by ObsiLP which adds Genetic-Science to Minecraft. Follow me on twitter https://twitter.com/jpplayer11 Minecraft Minecr...

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Hybrid Turkeys / Hendrix Genetics - Animal Aubsers - Office Invasion - Apr 11th, 2014
Below is a statement read by KOALA during the office occupation at Hybrid Turkeys/Hendrix Genetics @ 650 Riverbend Rd in Kitchener, ON on April 11th, 2014: A...

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Let #39;s Play The Sims 3 - Perfect Genetics - Episode 38
My Sims 3 Page: http://mypage.thesims3.com/mypage/Llandros2012 My Blog: http://Llandros09.blogspot.com My Facebook: https://www.facebook.com/Llandros09?

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[FTB][Minecraft] Lets Play Magic Farm 2 Episode 7: Bee Genetics Lesson ?

By: Basil-Leaf

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[FTB][Minecraft] Lets Play Magic Farm 2 Episode 7: Bee Genetics Lesson ? - Video

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Washington (PRWEB) April 15, 2014

Research that resulted in the first stem cells that are pluripotentthose that have the potential to differentiate into almost any cell in the bodywill be the backdrop for a discussion about trends in regulation in the field of regenerative medicine at the DIA 2014 50th Annual Meeting, June 15 to 19 in San Diego.

Chaired by Shinji Miyake, professor of clinical research for the Keio University School of Medicine in Japan, the session Pioneering Regenerative Medicine: Trends in Regulations for New Therapy will introduce the worlds first clinical research of induced pluripotent stem (iPS) cell products, conducted in Japan, and review updated regulatory guidance to bring regenerative medicine to patients who need healthy tissue or organs. The session will be held June 16 at 8:30 a.m. in the San Diego Convention Center.

iPS cells are stem cells that can be generated directly from adult cells. These cells can multiply indefinitely and represent a single source of cells, such as heart, neural, pancreatic and liver, that can be used to replace damaged cells.

In 2006, Japanese physician and researcher Shinya Yamanaka led a team to generate iPS cells from adult mouse tissue using gene therapy. This work led to a Nobel Prize in Physiology or Medicine in 2012 for the discovery that mature cells can be reprogrammed to become pluripotent.

We are honored to host pioneers of this unique field of medicine at the DIA Annual Meeting to share their experiences in the planning of the first clinical research of iPS cell productswhich have the ability to enhance research worldwide, said Barbara L. Kunz, DIA global chief executive. Their expert knowledge of issues and solutions in the application of the regenerative therapies will benefit all who advocate for and drive innovative medicine.

The session will also feature a presentation about the application of iPS cells to retinal diseases by Masayo Takahashi, project leader for the RIKEN Center for Developmental Biology in Japan, along with a European Medicines Agency (EMA) presentation by Dariusz Sladowski, researcher and member of the Committee for Advanced Therapies at EMA.

ABOUT DIA: DIA is the global connector in the life sciences product development process. Our association of more than 18,000 members builds productive relationships by bringing together regulators, innovators and influencers to exchange knowledge and collaborate in an impartial setting. DIAs network creates unparalleled opportunities for the exchange of knowledge and has the interdisciplinary experience to prepare for future developments. DIA is an independent, nonprofit organization with its global center in Washington, D.C., USA; regional offices covering North and South America (Horsham, Pa., USA); Europe, North Africa and the Middle East (Basel, Switzerland); and Japan (Tokyo), India (Mumbai) and China (Beijing). For more information, visit http://www.diahome.org.

ABOUT DIAs 2014 50th ANNUAL MEETING: Celebrate the Past Invent the Future is the largest multidisciplinary event that brings together a community of life sciences professionals at all levels and across all disciplines involved in the discovery, development and life cycle management of medical products. The meeting aims to foster innovation that will lead to the development of safe and effective medical products and therapies for patients. For more information, visit http://www.diahome.org/dia2014.

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Pioneers in Regenerative Therapy to Discuss New Trends in Stem Cell Medicine

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New York, NY (PRWEB) April 15, 2014

The Tisch MS Research Center of New York (Tisch MSRCNY) today announced that they surpassed their campaign goal on Indiegogo.com to raise funds for their FDA-Approved Phase I Clinical Stem Cell Trial. The funding will be directly applied to the study and stem cell research at Tisch MSRCNY.

The target of $300K was met and surpassed within the allotted four weeks of the campaign's launch raising a total amount of $317,540. We are overwhelmed and grateful for the generosity shown by our community of patients and friends, stated Dr. Saud A. Sadiq, Chief Research Scientist at Tisch MSRCNY and the studys principal investigator. He added, Funding is like oxygen for research. Without financial support, our research into regenerative therapy cannot survive.

As a non-profit,Tisch MS Research Center chose Indiegogo as a perfect platform since it has not received federal, state, or corporate funding to cover costs of this study. The crowd sourcing website heightened awareness and introduced new philanthropists to the Centers mission to repair the damage caused by multiple sclerosis.

The show of support has been tremendous, but our work is not done, said David Greenstein, Chairman of the Board of Directors at Tisch MSRCNY. We need the success of this campaign to jump start a steady stream of donations into the research center.

For more information on this study and to make a donation, visit: http://www.tischms.org

ABOUT TISCH MS RESEARCH CENTER OF NEW YORK For over twenty years, Dr. Saud A. Sadiq has believed that combining excellence in clinical care with innovative research targeted at finding the cure for multiple sclerosis would set an exemplary standard in the treatment of MS patients. Today, the Tisch MS Research Center of New York embodies this new model of healthcare, in which your doctor is also your researcher. Dr. Sadiq helps those with MS by conducting cutting-edge, patient-based research to ensure unparalleled care. The close relationship of the non-profit research center and its affiliated clinical practice (International Multiple Sclerosis Management Practice) enables the testing of new MS treatments and accelerates the pace at which research discoveries move from lab bench to bedside. The Tisch MS Research Center of New York aims to identify the disease trigger, optimize treatments for patients, and repair the damage caused by multiple sclerosis.

###

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Tisch MS Research Center of New York Exceeds $300K Crowdfunding Target for FDA-Approved Stem Cell Trial

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PUBLIC RELEASE DATE:

15-Apr-2014

Contact: Sophie Mohin smohin@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, April 15, 2014Transgender individuals are medically underserved and their healthcare needs incompletely understood in part because they represent a subpopulation whose health is rarely monitored by U.S. national surveillance systems. To address these issues, a new study compared methods of collecting and analyzing data to assess health disparities in a clinical sample of transgender individuals, as reported in an article published in LGBT Health, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the LGBT Health website at http://www.liebertpub.com/lgbt.

Sari Reisner, ScD and coauthors, Harvard School of Public Health, Harvard Medical School/Massachusetts General Hospital, and Fenway Health, Boston MA, compared transgender and non-transgender patients on health measures such as substance abuse, HIV infection, lifetime suicide attempts, and social stressors including violence and discrimination. They report their findings in the article "Transgender Health Disparities: Comparing Full Cohort and Nested Matched Pair Study Designs in a Community Health Center".

"Clinic-based samples and patient-related data are under-utilized sources of information about transgender health, particularly in community-based, urban health centers that typically serve large numbers of transgender patients," says Editor-in-Chief William Byne, MD, PhD, Icahn School of Medicine at Mount Sinai, New York, NY. "Reisner and coauthors describe a method of handling such data to provide valid results while maximizing efficiency with respect to time and resources."

###

About the Journal

Spanning a broad array of disciplines LGBT Health, published quarterly online with Open Access options and in print, brings together the LGBT research, health care, and advocacy communities to address current challenges and improve the health, well-being, and clinical outcomes of LGBT persons. The Journal publishes original research, review articles, clinical reports, case studies, legal and policy perspectives, and much more. Tables of content and a sample issue may be viewed on the LGBT Health website at http://www.liebertpub.com/lgbt.

About the Publisher

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New study from Harvard identifies transgender health disparities

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Ahmad Khalil started out studying how to build things like rocket engines and other mechanical systems as a mechanical engineering major in college. But, he added, he also took a liking to biology and the idea of applying engineering ideas to the study of living systems.

His PhD mentor, Angela Belcher at MIT, impressed upon him the reverse as well, that biological systems could also be used to engineer materials, and from her, he said, is where he got his "inspiration for bio-inspired engineering."

In his new lab at Boston University, Khalil is studying how cells respond to various environmental conditions and stressors.

"We develop engineering approaches and technologies to broadly study how cells behave, how they grow, how they develop, how they communicate," Khalil said, "and, in turn, to also re-direct those behaviors for useful applications for human health and energy and societal problems."

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Celera Researchers Investigating Genetic Risk Signature to Predict Atrial Fibrillation

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PUBLIC RELEASE DATE:

15-Apr-2014

Contact: Nathan Hurst hurstn@missouri.edu 573-882-6217 University of Missouri-Columbia

COLUMBIA, Mo. University of Missouri researchers have previously shown that a genetic pre-disposition to be more or less motivated to exercise exists. In a new study, Frank Booth, a professor in the MU College of Veterinary Medicine, has found a potential link between the genetic pre-disposition for high levels of exercise motivation and the speed at which mental maturation occurs.

For his study, Booth selectively bred rats that exhibited traits of either extreme activity or extreme laziness. Booth then put the rats in cages with running wheels and measured how much each rat willingly ran on their wheels during a six-day period. He then bred the top 26 runners with each other and bred the 26 rats that ran the least with each other. They repeated this process through 10 generations and found that the line of running rats chose to run 10 times more than the line of "lazy" rats.

Booth studied the brains of the rats and found much higher levels of neural maturation in the brains of the active rats than in the brains of the lazy rats.

"We looked at the part of the brain known as the 'grand central station,' or the hub where the brain is constantly sending and receiving signals," Booth said. "We found a big difference between the amount of molecules present in the brains of active rats compared to the brains of lazy rats. This suggests that the active rats were experiencing faster development of neural pathways than the lazy rats."

Booth says these findings may suggest a link between the genes responsible for exercise motivation and the genes responsible for mental development. He also says this research hints that exercising at a young age could help develop more neural pathways for motivation to be physically active.

"This study illustrates a potentially important link between exercise and the development of these neural pathways," Booth said. "Ultimately, this could show the benefits of exercise for mental development in humans, especially young children with constantly growing brains."

###

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Genetic pre-disposition toward exercise and mental development may be linked

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Long overdue skunkhouse genetics update
MMMP patient and caregiver in full compliance.

By: BolagnaSheetsMD .

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Long overdue skunkhouse genetics update - Video

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Let #39;s Play The Sims 3 - Perfect Genetics - Episode 37
This is the last of the #39;dark #39; videos #39; - it was buried and almost forgotten as I was cleaning out the computer files. My Sims 3 Page: http://mypage.thesims3....

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Let's Play The Sims 3 - Perfect Genetics - Episode 37 - Video

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Keyword Genetics | Use My Free System To Buy Keyword Genetics
Keyword Genetics - http://mikestotalfunnelsystem.com You found this video because you are probably trying to figure out how to make money from home with Keyw...

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Keyword Genetics | Use My Free System To Buy Keyword Genetics - Video

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Keyword Genetics
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Keyword Genetics - Video

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