Healthsouth - You Have a Choice (Spine)
This TV campaign for Healthsouth Rehabilitation Hospital is an emotional journey that speaks to the caretakers and family members of people who suffered trau...

By: Ben Consoli

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Healthsouth - You Have a Choice (Spine) - Video

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Sweden Medical Forum, part 14 - Dr. Petter Bjorquist, NovaHep
Dr. Petter Bjrquist, NovaHep AB "Development of biocompatible and individualized tissue engineered products using a novel stem cell technology" Find additio...

By: C0Orinir

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Sweden Medical Forum, part 14 - Dr. Petter Bjorquist, NovaHep - Video

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Marie, Quadriplegic, moves her legs on March 3rd, 2014.
Marie, Quadriplegic, moves her legs on March 3rd, 2014. Marie evaluating at Austin Hospital on September 13th, 2009 http://www.youtube.com/watch?v=l4cSTq6uy0...

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Marie, Quadriplegic, moves her legs on March 3rd, 2014. - Video

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Stem Cell Therapy for NFL Knee / ACL Injuries Sports Medicine - Dr Rodney Dade
WASHINGTONIAN Mag Top Doctor and Regenerative Medicine and Pain Management physician Dr Rodney Dade at StemCell ARTS discusses the tragic uptick in NFL knee ...

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Stem Cell Therapy for NFL Knee / ACL Injuries & Sports Medicine - Dr Rodney Dade - Video

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PUBLIC RELEASE DATE:

16-Mar-2014

Contact: Kara Gavin kegavin@umich.edu 734-764-2220 University of Michigan Health System

ANN ARBOR, Mich. Scientists have discovered a previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks -- a finding that opens the door to using this knowledge in testing or treatment of high cholesterol and other lipid disorders.

But even more significant is how they found the gene, which had been hiding in plain sight in previous hunts for genes that influence cardiovascular risk.

This region of DNA where it was found had been implicated as being important in controlling blood lipid levels in a report from several members of the same research team in 2008. But although this DNA region had many genes, none of them had any obvious link to blood lipid levels. The promise of an entirely new lipid-related gene took another six years and a new approach to find.

In a new paper in Nature Genetics, a team from the University of Michigan and the Norwegian University of Science and Technology report that they zeroed in on the gene in an entirely new way.

The team scanned the genetic information available from a biobank of thousands of Norwegians, focusing on variations in genes that change the way proteins function. Most of what they found turned out to be already known to affect cholesterol levels and other blood lipids.

But one gene, dubbed TM6SF2, wasn't on the radar at all. In a minority of the Norwegians who carried a particular change in the gene, blood lipid levels were much healthier and they had a lower rate of heart attack. And when the researchers boosted or suppressed the gene in mice, they saw the same effect on the animals' blood lipid levels.

"Cardiovascular disease presents such a huge impact on people's lives that we should leave no stone unturned in the search for the genes that cause heart attack," says Cristen Willer, Ph.D., the senior author of the paper and an assistant professor of Internal Medicine, Human Genetics and Computational Medicine & Bioinformatics at the U-M Medical School.

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Novel gene-finding approach yields a new gene linked to key heart attack risk factor

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Ricochet - Teens Discuss Genetic Engineering
This discussion originally took place on CHEK-TV in Victoria, British Columbia, and demonstrates a way to facilitate discussion with teens about challenging ...

By: Rey Carr

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Ricochet - Teens Discuss Genetic Engineering - Video

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Researchers at Virginia Tech and the Massachusetts Institute of Technology have used a computer-aided design tool to create genetic languages to guide the design of biological systems.

Known as GenoCAD, the open-source software was developed by researchers at the Virginia Bioinformatics Institute at Virginia Tech to help synthetic biologists capture biological rules to engineer organisms that produce useful products or health-care solutions from inexpensive, renewable materials.

GenoCAD helps researchers in the design of protein expression vectors, artificial gene networks, and other genetic constructs, essentially combining engineering approaches with biology.

Synthetic biologists have an increasingly large library of naturally derived and synthetic parts at their disposal to design and build living systems. These parts are the words of a DNA language and the "grammar" a set of design rules governing the language.

It has to be expressive enough to allow scientists to generate a broad range of constructs, but it has to be focused enough to limit the possibilities of designing faulty constructs.

MIT's Oliver Purcell, a postdoctoral associate, and Timothy Lu, an associate professor in the Department of Electrical Engineering and Computer Science, have developed a language detailed in ACS Synthetic Biology describing how to design a broad range of synthetic transcription factors for animals, plants, and other organisms with cells that contain a nucleus.

Meanwhile, Sakiko Okumoto, an assistant professor of plant pathology, physiology, and weed science at the Virginia Tech College of Agriculture and Life Sciences, and Amanda Wilson, a software engineer with the Synthetic Biology Group at the Virginia Bioinformatics Institute, developed a language describing design rules for expressing genes in the chloroplast of microalgae Their work was published in the Jan. 15 issue of Bioinformatics.

"Just like software engineers need different languages like HTML, SQL, or Java to develop different kinds of software applications, synthetic biologists need languages for different biological applications," said Jean Peccoud, an associate professor at the Virginia Bioinformatics Institute, and principal investigator of the GenoCAD project.

"From its inception, we envisioned GenoCAD as a framework allowing users to capture their expertise of a particular domain in languages that they could use themselves or share with others."

The researchers said encapsulating current knowledge by defining standards will become increasingly important as the number and complexity of components engineered by synthetic biologists increases.

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Researchers write languages to design synthetic living systems

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GoBigInternational #39;s Harborside GodBody Genetics Quality Cuts
I love my job for one and I appreciate all that watch my show. So today we will be showing the outdoor warm up for the season. The close and seeds are going ...

By: Nattie G

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GoBigInternational's Harborside & GodBody Genetics Quality Cuts - Video

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Formate Overview - Part 1
A brief overview of Formate output management software.

By: Document Genetics

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Formate Overview - Part 1 - Video

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MBC-Mods Week-Advanced Genetics and Vending Machine Mod
Day 6 of Mods Week and today we are looking at the Advance Genetics Mod and the Vending Machine Mod. Links: Resource Pack: Uber Science-http://www.minecraftf...

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MBC-Mods Week-Advanced Genetics and Vending Machine Mod - Video

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Law of Probability and Genetics

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Law of Probability and Genetics - Video

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Dr. Carl June on the Future of Treating Cancer
Dr. Carl June of the University of Pennsylvania School of Medicine discusses cancer gene therapy. When/Where: Alliance for Cancer Gene Therapy #39;s (ACGT) "Achi...

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Dr. Carl June on the Future of Treating Cancer - Video

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It is brain awareness week and University of Auckland researchers say they have developed a promising treatment for the 30 percent of epileptics who do not respond to drugs.

Researchers say it cuts the length of seizures in half and they hope to soon be able to tell whether it reduces the frequency of them too.

Epileptic Bevan McClay has been prescribed a cocktail of pills to help him manage, but the camera shop sales consultant just can't find the right combination to keep his epileptic seizures at bay.

"It gets a little bit frustrating sometimes," says Mr McClay.

Seizures affect one in every 100 people in New Zealand. That's 40,000 people. One-third of sufferers do not respond to conventional treatment.

But University of Auckland researches say they have discovered how to turn the gene off in the brain that is responsible for causing seizures.

"It could have a significant effect on any potential future treatment for epilepsy," says researcher Debbie Young.

How they do it is quite ingenious. They place a piece of synthetic DNA called a gene silencer inside a tiny capsule. That is injected and attaches to the cell containing the overactive gene. As the capsule breaks down, it releases the silencer, which switches off the overactive gene. That in turn releases increased levels of a chemical involved in stopping the seizures.

Researchers say the treatment can halve the length of seizures, and they are now looking at whether it can reduce the frequency of them too. That is giving hope to sufferers and those treating the disease.

"My clinics are full of people whom I feel I can help very little," says Dr Peter Bergin, a neurologist at Auckland Hospital and medical director for the Epilepsy Research programme. "It's enormously frustrating for me and I feel greatly for the patients."

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Gene therapy to help with epileptic seizures

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Turning Stem Cell Biology into Stem Cell Medicine
Mark Noble, Professor of Genetics, Neurology, Neurobiology and Anatomy; Director of the University of Rochester Stem Cell and Regenerative Medicine Institute...

By: UniversityRochester

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Turning Stem Cell Biology into Stem Cell Medicine - Video

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MANILA - The Securities and Exchange Commission (SEC) revoked the corporate registration of the Philippine Society for Stem Cell Medicine (PSSCM) for submitting fabricated endorsement from the Professional Regulation Commission (PRC).

In a five-page order, SEC acting director Ferdinand Sales said the PSSCM committed fraud in procuring its Certificate of Incorporation.

He said that as required under Section 17 of the Corporation Code, the PSSCM submitted a favorable endorsement from the PRC to support its application for corporate registration.

But he said the SEC found that the 2nd PRC Indorsement dated Feb. 20, 2013 submitted by PSSCM was falsified.

Considering the submission of a falsified PRC endorsement, there is fraud in procurement of respondents certificate of registration. The falsified document was relied upon by this Commission in approving the registration application of the respondent, Sales noted.

He added that had the SEC known about such defect early on, it would have not accepted and approved the registration application of the respondent.

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Registration of PH stem cell group revoked

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VIbes-Advanced Stem Cell Therapy PRP Treatment 12 Feb #39;14 - TV5 Hyderabad

By: Vibes Healthcare Ltd

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VIbes-Advanced Stem Cell Therapy & PRP Treatment 12 Feb'14 - TV5 Hyderabad - Video

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Stem Cell Therapy for NFL Knee / ACL Injuries Sports Medicine - Dr Rodney Dade
WASHINGTONIAN Mag Top Doctor and Regenerative Medicine and Pain Management physician Dr Rodney Dade at StemCell ARTS discusses the tragic uptick in NFL knee ...

By: StemCell ARTS

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Stem Cell Therapy for NFL Knee / ACL Injuries & Sports Medicine - Dr Rodney Dade - Video

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Personalized Medicine: Transforming Lung Cancer Treatment
For many years nearly all lung cancer patients received the same standard treatment. But new developments in genetic testing have allowed certain patients wi...

By: Herbert Irving Comprehensive Cancer Center at Columbia

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Personalized Medicine: Transforming Lung Cancer Treatment - Video

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Personalized Medicine in Bladder Cancer: A Summary of the Cancer Genome Atlas Findings
This presentation provides information about personalized medicine and what you should know about the Cancer Genome Atlas research findings in bladder cancer...

By: Bladder Cancer Advocacy Network

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Personalized Medicine in Bladder Cancer: A Summary of the Cancer Genome Atlas Findings - Video

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R3 Stem Cell Overview - Top Regenerative Medicine Clinics (844) GET-STEM
http://r3stemcell.com The top regenerative medicine clinics in the country are R3 Stem Cell Clinics. Stem Cell Therapy is offered for all musculoskeletal con...

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The parents of a 2-year-old Pasadena girl who was diagnosed with an aggressive form of leukemia have renewed their call for help in the search for a bone marrow donor, after stem cells taken from the girls father did not match.

Sofia Flores, shown in a family photo, needs a bone marrow donor.

The latest in a series of donor drives was held Saturday at Orchard Supply Hardware, located at 3425 E. Colorado Blvd. in Pasadena.

Sofia Flores story first came to light in October 2013 when her parents asked for help in finding a bone marrow donor for their daughter.

Sofia needed a marrow transplant to combat acute myeloid leukemia, according to A3M, a Los Angeles nonprofit that is helping Sofias parents seek a match for the little girl.

However, after an extensive search, no match was found.

On Jan. 23, her father donated his stem cells to her, which was the only alternative available at the time, according to Erica Westfall, Sofias mother.

But the treatment was not successful and Sofias cancer relapsed.

Sofias last chance for survival would be a transplant from an unrelated donor in the next two months, according to her mother.

Weve been searching for a bone marrow match even harder because this is her last chance, her father Ignacio Flores said in a video released to news media on Monday.

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Donor Drive Held for Pasadena Girl, 2, in Need of Bone Marrow Transplant

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VIbes-Advanced Stem Cell Therapy PRP Treatment 12 Feb #39;14 - TV5 Hyderabad

By: Vibes Healthcare Ltd

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VIbes-Advanced Stem Cell Therapy & PRP Treatment 12 Feb'14 - TV5 Hyderabad - Video

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By Sean Williams | More Articles March 11, 2014 |

Although we don't believe in timing the market or panicking over market movements, we do like to keep an eye on big changes -- just in case they're material to our investing thesis.

What: Shares of Myriad Genetics (NASDAQ: MYGN) , a company focused on developing molecular diagnostic tests, sank as much as 13% after a U.S. court denied a motion to block a rival from selling a competing BRCA gene diagnostic test.

So what: According to the ruling, a Utah court denied Myriad Genetics' attempt to put a temporary stop to rival Ambry Genetics' ability to market its BRCA 1 and BRCA 2 gene tests. These genes are commonly linked to a higher chance of developing breast and/or ovarian cancer in women. Myriad has laid claim to the patents surrounding the BRCA 1 & BRCA 2 genes for years, using those patent claims to protect its BRACAnalysis test from any competitors. However, a Supreme Court ruling in June last year determined that genes which naturally occur in the body aren't patentable, opening up Myriad's test to competitors. In its 8-K filing, Myriad asserts that it believes its patents are valid, and that it anticipates being victorious. Despite that optimism, no trial date has been scheduled as of yet.

Now what: Following Myriad Genetics is like watching a soap opera just when things begin to calm down a new plot twist enters the picture. As if Myriad didn't have enough ongoing competitive issues, the Centers for Medicare and Medicaid Services recently proposed a nearly 50% reduction in reimbursement rates to its BRACAnalysis test. Although Medicare only makes up a smaller portion of Myriad's total revenue, its BRACAnalysis test made up 69% of total revenue as of the last reported quarter. In other words, Myriad has a lot on the line here.

Ultimately, I'm very excited for the potential of Myriad's prostate cancer diagnostic test, Prolaris, which helps with staging, and feel that as the U.S. population ages the need to offer personalized medical treatment will only further improve the diagnostic landscape. Over the near-term, though, an unclear Medicare reimbursement picture and a bevy of potential competitors makes Myriad a risky investment.

Although Myriad has soared this year, chances are it'll have a tough time keeping up with this top stock in 2014 There's a huge difference between a good stock and a stock that can make you rich. The Motley Fool's chief investment officer has selected his No. 1 stock for 2014, and it's one of those stocks that could make you rich. You can find out which stock it is in the special free report "The Motley Fool's Top Stock for 2014." Just click here to access the report and find out the name of this under-the-radar company.

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Why Myriad Genetics, Inc. Shares Were Spliced

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by Dhaneshi Yatawara

A cancer genetics clinic will be conducted by the Human Genetics Unit of the University of Colombo at the Maharagama National Cancer Institute. The clinic will be held every Friday afternoon.

The purpose of the clinic is to identify individuals having hereditary cancer syndromes and provide thorough evaluation, genetic counselling and testing which will be beneficial for the patients and their families, according to Professor Vajira Dissanayake of the Human Genetics Unit, Colombo University.

"We will work with physicians and surgeons who treat the patients. The clinic is ready to provide service not only to cancer patients but also to their family members as well," Prof. Dissanayake said.

The cancer genetics clinic will conduct risk assessments for each patient for all forms of cancers and screening for early detection management, Genetic counselling and genetic testing.

"Members of families with records of cancer occurring in multiple generations or people with two or more close relatives having the same cancer can come to the clinic and get their risk assessments," he said.

And for those who underwent treatment for cancer that occurred in one section of paired organs of the body have the facility to check whether the cancer has spread to the other half of the organ. Several main genetic tests will be available at the clinic.

Tests to check effectiveness of the drugs on individual cancer patients medically known as pharmacogenomic tests, are also available at the clinic.

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Genetics clinic at Cancer Institute

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Dr. Michel Sadelain: How Gene Therapy Beats Cancer
Dr. Michel Sadelain of Memorial Sloan-Kettering Cancer Center discusses cancer gene therapy. When/Where: Alliance for Cancer Gene Therapy #39;s (ACGT) "Achieving...

By: ACGTFoundation

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Dr. Michel Sadelain: How Gene Therapy Beats Cancer - Video

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