Advanced Genetics (Updated to 1.6.4)
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Genetics practice
genetics practice.

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Mod Spotlight Advanced Genetics 1.6.4 v1.2.1
Minecraft FTB Monster Advanced Genetics Mod Spotlight. Check Out My Other Mod Spotlights! http://j.gs/35Sc Be sure to Like, Comment, Sub, and Share! Subscrib...

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Gene therapy for back pain
Nine News, Melbourne, 6pm, 30/1/2014.

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Questions Answers 208
In This Video: 01:26 -- Curt -- Is there any chance that the growth factors in Deer Antler could grow a tumor or make it harder to remove one? 04:53 -- Jal -...

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Pup Named #39;Abby #39; Learns to Walk With Help From Wheels
Recently, a three-month-old Aussie pup named Abby got to take her first steps with help from a Massachusetts based company, Eddie #39;s Wheels. Her journey in le...

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SCI Short: Staying Active
Concerts, restaurants, nature...you name it. Staying active after a Spinal Cord Injury is easier than you might think!

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Stem Cell Breakthrough
Stem cell researchers are heralding a "major scientific discovery", with the potential to start a new age of personalised medicine. Scientists in Japan showe...

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There are exciting developments in the field of stem cell research which could make the whole thing cheaper, easier, and much quicker. According to a Jan. 29 report on BBC News, scientists have discovered that skin cells can become stem cells when they are dipped in acid, lowering the PH balance of the cell.

Stem cells can adapt to become almost any organ in the body, while other cells in the body have a particular purpose, such as liver or heart. So, by bypassing such controversial methods as the use of embryonic stem cells, the near future could hold a much faster, more personalized use of stem cells in many areas of medicine.

These initial findings have been compiled with research from mice, and the research is now being carried over into the human realm. While the new findings have a way to go before being directly beneficial to patients, once the stem cell research therapies are established, these new findings will make it much more accessible.

You can read more about the basic science of stem cell research on Medical News Today.

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6th Borough - Cell Therapy
Another Track That was in the Vault, Figure I Release it Since It #39;s Throwback Thursday They Say... Shouts Out to The Goodie Mob.

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Adipose Derived Cell Therapy

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Purtier Placenta Stem Cell Therapy Presented By Dr. Chen
Presentasi Purtier Placenta oleh Dr. Chen Nikmati hidup bebas rasa sakit dan selalu awet muda bersama Purtier Placenta: http://www.stemcellworld.net.

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Newswise NEW YORK (January 30, 2014) Steven Libutti, M.D., F.A.C.S., professor and vice chairman in the Department of Surgery at Montefiore Medical Center and Albert Einstein College of Medicine at Yeshiva University, director at the Montefiore Einstein Center for Cancer Care and professor in the Department of Genetics and associate director of clinical services at Albert Einstein College of Medicine has been named Editor-in-Chief of Cancer Gene Therapy, a journal for cancer researchers and clinicians.

Cancer Gene Therapy serves as a respected resource for scientists and clinicians on the latest gene and cellular therapies for cancer. Topics will range from DNA synthesis and repair to the latest original laboratory research and case reports on translational research and tumor immunotherapies.

The progression of personalized cancer treatments and evolution of new technologies for monitoring genetic changes holds new promise for those impacted by cancer, said Dr. Libutti. Cancer Gene Therapy will cover innovative scientific developments and prompt clinical questions that I hope spark new perspectives and industry dialogue about whats next.

As a pioneer in tumor-targeted gene therapy, Dr. Libutti is developing novel cancer therapies through his study of the complex interactions that occur within a tumors microenvironment. Since 2009, he has spearheaded multidisciplinary efforts in research and treatment of cancer at the Montefiore Einstein Center for Cancer Care.

We feel honored to be working in conjunction with an expert of Dr. Libuttis caliber, said Andrea Macaluso, publishing manager, Nature Publishing Group. His vast experience discovering new and effective ways to treat cancer combined with his record of excellent basic research and clinical care made him a natural choice to lead our journal and further strengthen Nature Publishing Groups library of scientific and medical publications.

Dr. Libutti is an internationally recognized expert in surgical oncology and endocrine surgery and has published more than 250 peer-reviewed journal articles and 16 oncology book chapters. He has received the NIH Directors Award and the National Cancer Institutes Directors Gold Star and Intramural Innovation Awards. Dr. Libutti also has appeared on Castle Connollys list of Top Doctors in America and on New York Magazines list of Top Doctors in New York. In 2009, he was named the Marvin L. Gliedman, M.D., Distinguished Surgeon at Montefiore Medical Center. Prior to being appointed director of the Montefiore Einstein Center for Cancer Care, Dr. Libutti was a researcher, surgeon and Section Head at the National Cancer Institute.

About Montefiore Medical Center As the University Hospital for Albert Einstein College of Medicine, Montefiore is a premier academic medical center nationally renowned for its clinical excellence, scientific discovery and commitment to its community. Recognized among the top hospitals nationally and regionally by U.S. News & World Report, Montefiore provides compassionate, patient- and family-centered care and educates the healthcare professionals of tomorrow. The Children's Hospital at Montefiore is consistently named in U.S. News' "America's Best Children's Hospitals." With four hospitals, 1,491 beds and 90,000 annual admissions, Montefiore is an integrated health system seamlessly linked by advanced technology. State-of-the-art primary and specialty care is provided through a network of more than 130 locations across the region, including the largest school health program in the nation and a home health program. Montefiore's partnership with Einstein advances clinical and translational research to accelerate the pace at which new discoveries become the treatments and therapies that benefit patients. The medical center derives its inspiration for excellence from its patients and community, and continues to be on the frontlines of developing innovative approaches to care. For more information please visit http://www.montefiore.org and http://www.montekids.org. Follow us on Twitter; like us on Facebook; view us on YouTube.

About Albert Einstein College of Medicine of Yeshiva University Albert Einstein College of Medicine of Yeshiva University is one of the nations premier centers for research, medical education and clinical investigation. During the 2013-2014 academic year, Einstein is home to 734 M.D. students, 236 Ph.D. students, 106 students in the combined M.D./Ph.D. program, and 353 postdoctoral research fellows. The College of Medicine has more than 2,000 full-time faculty members located on the main campus and at its clinical affiliates. In 2013, Einstein received more than $155 million in awards from the NIH. This includes the funding of major research centers at Einstein in diabetes, cancer, liver disease, and AIDS. Other areas where the College of Medicine is concentrating its efforts include developmental brain research, neuroscience, cardiac disease, and initiatives to reduce and eliminate ethnic and racial health disparities. Its partnership with Montefiore Medical Center, the University Hospital and academic medical center for Einstein, advances clinical and translational research to accelerate the pace at which new discoveries become the treatments and therapies that benefit patients. Through its extensive affiliation network involving Montefiore, Jacobi Medical Center Einsteins founding hospital, and five other hospital systems in the Bronx, Manhattan, Long Island and Brooklyn, Einstein runs one of the largest residency and fellowship training programs in the medical and dental professions in the United States. For more information, please visit http://www.einstein.yu.edu, read our blog, follow us on Twitter, like us on Facebook, and view us on YouTube.

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Jan 31, 2014 by Jennie Matthew Swans are pictured on a lake in Slovakia on December 29, 2010

In Britain, wild swans may be prized for their beauty and protected by the Queen, but the US state of New York has declared war on them, branding them a violent menace.

Draft proposals to kill or resettle the state's 2,200 wild mute swans by 2025 may be supported by some conservationists but have sparked uproar among animal rights activists.

Mute swans were brought to North America by European settlers to adorn their estates in the late 1800s but the authorities no longer consider them a beauty worthy of roaming free.

The New York state department of environmental conservation says swans attack people, destroy vegetation, pose a threat to jetliners and damage water because their feces contain e coli.

Ever since US Airways flight 1549 collided with a flock of geese in 2009 and landed on the Hudson river, the US Department of Agriculture has set about annually culling Canada geese.

Now the New York state conservation department wants to expand the offensive and eliminate free-ranging mute swans by 2025, killing them or allowing "responsible ownership" of the birds in captivity.

"Lethal control methods will include shooting of free-ranging swans and live capture and euthanasia in accordance with established guidelines for wildlife," said the draft proposal.

Nests would also be destroyed, and eggs oiled, punctured or sterilized to prevent hatching, it added.

Pressure group Goose Watch NYC, which was set up to protest against the geese culls, demanded the plan be scrapped.

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New York declares war on swans

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Jan 31, 2014 by Fred Love Amy Toth is one of several ISU faculty members working to understand the decline of pollinating insects. Credit: Bob Elbert.

Last spring, when Mary Harris started looking for particular pesticides in the pollen carried by honey bees in northwest Iowa, she didn't find any. But that changed the week tractors hit the fields to plant crops.

That week, every pollen sample she took tested positive for the presence of neonicotinoids, pesticides often used to coat seeds before they're planted.

Harris, an Iowa State University adjunct assistant professor of natural resource ecology and management, was part of a research team formed by the nonprofit Pollinator Partnership to monitor the level of neonicotinoid pesticides found in plant pollen collected by honey bees. The research, released on Thursday, indicates that the pesticides also contaminate nearby plants that are visited by a range of helpful pollinating insects.

Harris's effort to study pesticides is one thread in a patchwork of research at Iowa State to identify the factors that have led to steep declines in the populations of pollinating insects in Iowa and across the globe.

ISU faculty members have found several causes that likely lie at the heart of the problem, each one compounding the others.

"People want a single issue to blame it on, and that would be great because we could fix it," said Amy Toth, an assistant professor of ecology, evolution and organismal biology. "But it's not that simple."

Over the last five years, average annual winter losses among U.S. beekeepers have totaled about 30 percent, said Andrew Joseph, the state apiarist for the Iowa Department of Agriculture. That means that American beekeepers are losing almost a third of their bees each winter. Iowa beekeepers have seen even higher mortality, with average annual losses reaching 54.1 percent during that time period, Joseph said.

It's a growing crisis that could eventually drive up costs at grocery stores for a range of foods that can't reach store shelves without the help of pollinators.

Neonics on the wind

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Jan 31, 2014 by Bob Yirka Mirabilis jalapa (the four o'clock flower). This plant is the host of Phytophthora mirabilis, the sister species of the Irish potato famine pathogen Phytophthora infestans. Credit: Sophien Kamoun, The Sainsbury Laboratory (Norwich, UK)

(Phys.org) A research team with members from the U.K., Germany and the U.S. has identified an amino acid sequence in effector proteins in two pathogens that helps explain how a firmly established pathogen can leap from one plant to another. In their paper published in the journal Science, the team describes genomic research they conducted on two types of well-known plant pathogens and what it revealed regarding effector proteins and their role in helping the pathogen jump from one plant species to another.

Understanding how plant pathogens jump from one plant to another can help prevent severe outbreaks such as the famous potato famine in Ireland back in the 19th century. Scientists suspect it as to do with evolutionary developments in effector proteinsthose proteins produced by a pathogen that disable pathogen fighting proteins in the host. In this new effort, the researchers looked at two particular types of pathogens, Phytophthora infestans and Phytophthora mirabilisthey are believed to have diverged from a single parent approximately 1,200 years agorecently enough to have left behind evidence of what caused them to go their separate ways.

P. infestans is the pathogen responsible for the potato famine. P. mirabilis on the other hand, is only able to infect a plant known as the four o'clock flower. To uncover what made the divergence possible, the researchers picked up where another team had left off back in 2010that team had found evidence of adaptive evolution in 82 effector genesthose responsible for the creation of effector proteins. The new team looked at just one of those genes and found that the proteins that were produced by each plantprotease inhibitorsbound more strongly to proteases from their host plants than to those of the other host plant, suggesting a genetic predisposition. That explained their ability to infect one host but not another.

In taking a closer look at the effector proteins, the researchers found just one single amino acid difference in the two pathogens. Thus it appears that the divergence of the two pathogens came down to a simple evolutionary development in a single amino acid. More striking perhaps was the realization that such a small difference between pathogens can mean the difference between which types of plants can be infectedjumping to another plant generally renders the pathogen unable to infect its original host.

Explore further: How an aggressive fungal pathogen causes mold in fruits and vegetables

More information: Effector Specialization in a Lineage of the Irish Potato Famine Pathogen, Science 31 January 2014: Vol. 343 no. 6170 pp. 552-555. DOI: 10.1126/science.1246300

Abstract Accelerated gene evolution is a hallmark of pathogen adaptation following a host jump. Here, we describe the biochemical basis of adaptation and specialization of a plant pathogen effector after its colonization of a new host. Orthologous protease inhibitor effectors from the Irish potato famine pathogen, Phytophthora infestans, and its sister species, Phytophthora mirabilis, which is responsible for infection of Mirabilis jalapa, are adapted to protease targets unique to their respective host plants. Amino acid polymorphisms in both the inhibitors and their target proteases underpin this biochemical specialization. Our results link effector specialization to diversification and speciation of this plant pathogen.

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Journal reference: Science

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Researchers identify amino acid change that allows pathogens to jump from one plant to another

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Genetic research is focused on which specific genes are involved in the inflammatory process, immune response, and breakdown of cartilage. Understanding the genetic connection may lead to a cure or better treatment options for arthritis and related conditions.

Is Arthritis Hereditary? If a family member has arthritis, should you worry? Is arthritis hereditary?

HLA-B27 and HLA-DR4 - Arthritis and the Genetic Factor Genetics has become the focal point of new and ongoing arthritis research.

Senior Mobility Gene JAMA reports that the presence of a particular geotype that interacts with exercise to enhance mobility in seniors.

Clinical Trials: Gene Therapy Clinical trials for gene therapy, from ClinicalTrials.gov.

Genomics & Health Weekly Update This weekly update provides information about the impact of human genetic research on disease prevention and public health, from CDC.

The Human Genome Project (1990-2003) Completed in 2003, the Human Genome Project (HGP) was a 13-year project. Explore this site for information about the Human Genome Project (1990-2003), from ORNL.gov.

The New Genetics: National Institute of General Medical Sciences The New Genetics explains how genes affect your health. The New Genetics describes the basics of how DNA and RNA work. It also explains how studies of evolution drive medical research, how genes influence health and disease, and how computer science is advancing genetics in the 21st century.

NHGRI: The National Human Genome Research Institute The National Human Genome Research Institute led the Human Genome Project for the National Institutes of Health, which culminated in the completion of the full human genome sequence in April 2003. Now, NHGRI moves forward into the genomic era with research aimed at improving human health and fighting disease.

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PUBLIC RELEASE DATE:

31-Jan-2014

Contact: Julie O'Connor julie.oconnor@wayne.edu 313-577-8845 Wayne State University - Office of the Vice President for Research

DETROIT A research team led by Wayne State University, in collaboration with Michigan State University, has identified a single gene in honeybees that separates the queens from the workers.

The scientists unraveled the gene's inner workings and published the results in the current issue of Biology Letters. The gene, which is responsible for leg and wing development, plays a crucial role in the evolution of bees' ability to carry pollen.

"The gene Ultrabithorax, or Ubx is responsible for making hind legs different from fore legs so they can carry pollen" said Aleksandar Popadic, associate professor of biological sciences in Wayne State University's College of Liberal Arts and Science and principal investigator of the study. "In some groups, like crickets, Ubx is responsible for creating a 'jumping' hind leg. In others, such as bees, it makes a pollen basket a 'naked,' bristle-free leg region that creates a space for packing pollen."

"Other studies have shed some light on this gene's role in this realm, but our team examined in great detail how the modifications take place," added Zachary Huang, MSU entomologist.

Ubx represses the development of bristles on bees' hind legs, creating a smooth surface that can be used for packing pollen. This important discovery can be used as a foray into more commercial studies focused on providing means to enhance a bee's pollination ability the bigger the pollen basket, the more pollen that can be packed in it and transported back to the hive.

While workers have these distinct features, queens do not. The team confirmed this by isolating and silencing Ubx. This made the pollen baskets completely disappear, altered the growth of the pollen comb and reduced the size of the pollen press. Interestingly, Ubx is also expressed in the same region of the hind legs in bumble bees, which are in the same family as honey bees. This finding suggests that the evolution of the pollen-gathering apparatus in all corbiculate bees may have a shared origin and could be traced to the acquisition of novel functions by Ubx.

In another interesting finding, researchers identified that bees living in more complex social structures have an advantage over isolated populations in developing these important functions.

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Research led by Wayne State discovers single gene in bees separating queens from workers

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Newswise DETROIT A research team led by Wayne State University, in collaboration with Michigan State University, has identified a single gene in honeybees that separates the queens from the workers.

The scientists unraveled the genes inner workings and published the results in the current issue of Biology Letters. The gene, which is responsible for leg and wing development, plays a crucial role in the evolution of bees ability to carry pollen.

The gene Ultrabithorax, or Ubx is responsible for making hind legs different from fore legs so they can carry pollen said Aleksandar Popadic, associate professor of biological sciences in Wayne State Universitys College of Liberal Arts and Science and principal investigator of the study. In some groups, like crickets, Ubx is responsible for creating a jumping hind leg. In others, such as bees, it makes a pollen basket a naked, bristle-free leg region that creates a space for packing pollen.

Other studies have shed some light on this genes role in this realm, but our team examined in great detail how the modifications take place, added Zachary Huang, MSU entomologist.

Ubx represses the development of bristles on bees hind legs, creating a smooth surface that can be used for packing pollen. This important discovery can be used as a foray into more commercial studies focused on providing means to enhance a bees pollination ability the bigger the pollen basket, the more pollen that can be packed in it and transported back to the hive.

While workers have these distinct features, queens do not. The team confirmed this by isolating and silencing Ubx. This made the pollen baskets completely disappear, altered the growth of the pollen comb and reduced the size of the pollen press. Interestingly, Ubx is also expressed in the same region of the hind legs in bumble bees, which are in the same family as honey bees. This finding suggests that the evolution of the pollen-gathering apparatus in all corbiculate bees may have a shared origin and could be traced to the acquisition of novel functions by Ubx.

In another interesting finding, researchers identified that bees living in more complex social structures have an advantage over isolated populations in developing these important functions.

The pollen baskets are much less elaborate or completely absent in bees that are less socially complex, Huang said. We conclude that the evolution of pollen baskets is a major innovation among social insects and is tied directly to more complex social behaviors.

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Research Team Discovers Single Gene in Bees Separating Queens From Workers

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PUBLIC RELEASE DATE:

31-Jan-2014

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 x2156 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, January 31, 2014In recognition of his seminal work on adenoviral vectors, which accelerated the translation of gene therapy from the research laboratory to the clinic, Ronald G. Crystal, MD (Weill Cornell Medical College, Cornell University, New York City), has received a Pioneer Award from Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. Human Gene Therapy is commemorating its 25th anniversary by bestowing this honor on the leading 12 Pioneers in the field of cell and gene therapy selected by a blue ribbon committee* and publishing a Pioneer Perspective by each of the award recipients. The article by Dr. Crystal is available on the Human Gene Therapy website.

Currently it is standard practice to use a modified virus as a transport vehicle to deliver therapeutic genes to patients. But this concept was new, innovative, and technically challenging when Dr. Crystal began developing the molecular tools and methods in the late 1980s. In the Pioneer Perspective "Adenovirus: The First Effective In Vivo Gene Delivery Vector," Dr. Crystal provides historical insights on the many years of research and testing needed to design, optimize, manufacture, and evaluate the performance of adenoviral vectors. He describes the first in vivo studies, the first human studies, and the many current applications of this useful gene delivery system.

"Ron led the way in the clinical translation of adenoviral vectors in the very early days of gene therapy," says James M. Wilson, MD, PhD, Editor-in-Chief of Human Gene Therapy, and Director of the Gene Therapy Program, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.

###

*The blue ribbon panel of leaders in cell and gene therapy, led by Chair Mary Collins, PhD, MRC Centre for Medical Molecular Virology, University College London, selected the Pioneer Award recipients. The Award Selection Committee selected scientists that had devoted much of their careers to cell and gene therapy research and had made a seminal contribution to the field--defined as a basic science or clinical advance that greatly influenced progress in translational research.

About the Journal

Human Gene Therapy, the official journal of the European Society of Gene and Cell Therapy, British Society for Gene and Cell Therapy, French Society of Cell and Gene Therapy, German Society of Gene Therapy, and five other gene therapy societies, is an authoritative peer-reviewed journal published monthly in print and online. Human Gene Therapy presents reports on the transfer and expression of genes in mammals, including humans. Related topics include improvements in vector development, delivery systems, and animal models, particularly in the areas of cancer, heart disease, viral disease, genetic disease, and neurological disease, as well as ethical, legal, and regulatory issues related to the gene transfer in humans. Its sister journals, Human Gene Therapy Methods, published bimonthly, focuses on the application of gene therapy to product testing and development, and Human Gene Therapy Clinical Development, published quarterly, features data relevant to the regulatory review and commercial development of cell and gene therapy products. Tables of content for all three publications and a free sample issue may be viewed on the Human Gene Therapy website.

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Ronald Crystal, M.D., receives Pioneer Award

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MineCraft Modded Survival Cac Tech #4 Advanced Genetics

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Cancer Genetics, Inc. (NASDAQCM: CGIX): RedChip Emerging Growth Showcase (January 22-23, 2014)
Virtual Conference Presentation and Investor Q A with Panna Sharma, CEO of Cancer Genetics, Inc. (NASDAQCM: CGIX), an emerging leader in the field of persona...

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The Biology of Genetics
Learn what goes in to making you, you.

By: Bill Nye

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The Biology of Genetics - Video

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Stretch Goal Cast - Episode #4: Jurassic Genetics, Divinity: Original Sin The Castle Doctrine
Your SGC podcasting crew shrinks to three this week with Jared, Justin and Clinton presiding over the main topics. Jared kicks things off with some genuine, ...

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Stem Cell Therapy - Obat segala penyakit
Stem cell therapy terbukti mampu sembuhkan kanker, stroke, diabetes, jantung, Parkinson, Alzheimer, AIDS, dll.

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