Report of the American Society of Human Genetics Ancestry Inference Roundtable - Malia Fullerton
September 12, 2013 - The African Diaspora: Integrating Culture, Genomics and History.

By: GenomeTV

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Report of the American Society of Human Genetics Ancestry Inference Roundtable - Malia Fullerton - Video

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Report of the American Society of Human Genetics Ancestry Inference Roundtable - Charmaine Royal
September 12, 2013 - The African Diaspora: Integrating Culture, Genomics and History.

By: GenomeTV

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Report of the American Society of Human Genetics Ancestry Inference Roundtable - Charmaine Royal - Video

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Identity and Genetics (Introduction) - Yolanda Moses
September 12, 2013 - The African Diaspora: Integrating Culture, Genomics and History.

By: GenomeTV

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Identity and Genetics (Introduction) - Yolanda Moses - Video

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Report of the American Society of Human Genetics Ancestry Inference Roundtable (Panel)
September 12, 2013 - The African Diaspora: Integrating Culture, Genomics and History.

By: GenomeTV

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Report of the American Society of Human Genetics Ancestry Inference Roundtable (Panel) - Video

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DNA GENETICS AMSTERDAM 2013
DNA GENETICS AMSTERDAM http://www.dnagenetics.com DNA Genetics Sint Nicolaasstraat 41 Amsterdam TheHashCompany Cannabis Entertainment Amsterdam http://www....

By: TheHashCompany

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DNA GENETICS AMSTERDAM 2013 - Video

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Personalized Medicine and its role in Africa by Dr R T Erasmus

By: Genetalk

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Personalized Medicine and its role in Africa by Dr R T Erasmus - Video

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Aspire - James #39;s Story
James has a spinal cord injury and it #39;s turned his life upside down - not because of the injury itself but because he didn #39;t have anywhere accessible to live...

By: Aspire Charity

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A Nurse #39;s Testament on Adult Stem Cell Therapy for Back Pain
A registered nurse describes her experience with an adult stem cell therapy procedure for back pain. More information at medrebels.org.

By: Med Rebels

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A Nurse's Testament on Adult Stem Cell Therapy for Back Pain - Video

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News Release: Dr. Andrew Cappuccino #39;s Insight on Adult Stem Cell Therapy
Dr. Andew Cappuccino, team orthopedist for the Buffalo Bills, gives insight on using Adult Stem Cells to treat back pain. More information at http://medrebel...

By: Med Rebels

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News Release: Dr. Andrew Cappuccino's Insight on Adult Stem Cell Therapy - Video

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Public Lecture; Kevin Mitchell, Smurfit Institute of Genetics, Trinity College Dublin
"The Miswired Brain" Public Lecture 7/17/2013.

By: CSHL Leading Strand

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Public Lecture; Kevin Mitchell, Smurfit Institute of Genetics, Trinity College Dublin - Video

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Great young lyretail genetics,
2 that are lyretails that show 1 red with out lyretail showing but of same genetics as the 2 above remaing are of the same genetics but black.

By: ziouxpioux

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Great young lyretail genetics, - Video

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Alliance for Cancer Gene Therapy- Full Program at Harvard Club on October 15,2013
Alliance for Cancer Gene Therapy #39;s top researchers and physicians discuss the success of gene and cell therapy at the Harvard Club on October 15, 2013.

By: Matthew Lagle

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Alliance for Cancer Gene Therapy- Full Program at Harvard Club on October 15,2013 - Video

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Mom #39;s gene therapy interview
Jake #39;s gene therapy interview with mom.

By: Julie Perine

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Mom's gene therapy interview - Video

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MedRebels: A Quick ACL Recovery due to Adult Stem Cell Therapy [Storm Dunworth]
Storm Dunworth, a highschool athlete, uses adult stem cells to help with the recovery from an ACL injury. Hear her story. More information at http://medrebel...

By: Med Rebels

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MedRebels: A Quick ACL Recovery due to Adult Stem Cell Therapy [Storm Dunworth] - Video

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Report of the American Society of Human Genetics Ancestry (Introduction) - Vence Bonham
September 12, 2013 - The African Diaspora: Integrating Culture, Genomics and History.

By: GenomeTV

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Report of the American Society of Human Genetics Ancestry (Introduction) - Vence Bonham - Video

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Personalized Medicine Partnering Terms and Agreements
Personalized Medicine Partnering Terms and Agreements Report @ http://www.reportsnreports.com/reports/148935-personalized-medicine-partnering-terms-agreement...

By: ohanna johnson

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St. Luke #39;s Personalized Medicine Commercial

By: ASRmediaProductions

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Prof. Charles ffrench-Constant - Why Doesn #39;t the Brain Repair Itself?
Professor Charles ffrench-Constant, Professor of Multiple Sclerosis Research, presents the Medical Detectives lecture, "Why Doesn #39;t the Brain Repair Itself?"...

By: EdinburghUniversity

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What Is Stem Cell Therapy? Get The Candy Coated Illustration - Dr. Bill Johnson, Dallas
http://www.InnovationsStemCellCenter.com (214) 699-6948 Find out just how your own body #39;s stem cells can help you build new cells that have been damaged. SVF...

By: dallasdrj

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What Is Stem Cell Therapy? Get The Candy Coated Illustration - Dr. Bill Johnson, Dallas - Video

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Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into red blood cells, which carry oxygen throughout the body, white blood cells, which fight infections, and platelets, which help the to blood clot.

A bone marrow transplant is a procedure that replaces a person's faulty bone marrow stem cells. Doctors use these transplants to treat people with certain diseases, such as

Before you have a transplant, you need to get high doses of chemotherapy and possibly radiation. This destroys the faulty stem cells in your bone marrow. It also suppresses your body's immune system so that it won't attack the new stem cells after the transplant.

In some cases, you can donate your own bone marrow stem cells in advance. The cells are saved and then used later on. Or you can get cells from a donor. The donor might be a family member or unrelated person.

Bone marrow transplantation has serious risks. Some complications can be life-threatening. But for some people, it is the best hope for a cure or a longer life.

NIH: National Heart, Lung, and Blood Institute

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Bone Marrow Transplantation: MedlinePlus - National Library of ...

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With more than 50 years of experience studying blood-forming stem cells called hematopoietic stem cells, scientists have developed sufficient understanding to actually use them as a therapy. Currently, no other type of stem cell, adult, fetal or embryonic, has attained such status. Hematopoietic stem cell transplants are now routinely used to treat patients with cancers and other disorders of the blood and immune systems. Recently, researchers have observed in animal studies that hematopoietic stem cells appear to be able to form other kinds of cells, such as muscle, blood vessels, and bone. If this can be applied to human cells, it may eventually be possible to use hematopoietic stem cells to replace a wider array of cells and tissues than once thought.

Despite the vast experience with hematopoietic stem cells, scientists face major roadblocks in expanding their use beyond the replacement of blood and immune cells. First, hematopoietic stem cells are unable to proliferate (replicate themselves) and differentiate (become specialized to other cell types) in vitro (in the test tube or culture dish). Second, scientists do not yet have an accurate method to distinguish stem cells from other cells recovered from the blood or bone marrow. Until scientists overcome these technical barriers, they believe it is unlikely that hematopoietic stem cells will be applied as cell replacement therapy in diseases such as diabetes, Parkinson's Disease, spinal cord injury, and many others.

Blood cells are responsible for constant maintenance and immune protection of every cell type of the body. This relentless and brutal work requires that blood cells, along with skin cells, have the greatest powers of self-renewal of any adult tissue.

The stem cells that form blood and immune cells are known as hematopoietic stem cells (HSCs). They are ultimately responsible for the constant renewal of bloodthe production of billions of new blood cells each day. Physicians and basic researchers have known and capitalized on this fact for more than 50 years in treating many diseases. The first evidence and definition of blood-forming stem cells came from studies of people exposed to lethal doses of radiation in 1945.

Basic research soon followed. After duplicating radiation sickness in mice, scientists found they could rescue the mice from death with bone marrow transplants from healthy donor animals. In the early 1960s, Till and McCulloch began analyzing the bone marrow to find out which components were responsible for regenerating blood [56]. They defined what remain the two hallmarks of an HSC: it can renew itself and it can produce cells that give rise to all the different types of blood cells (see Chapter 4. The Adult Stem Cell).

A hematopoietic stem cell is a cell isolated from the blood or bone marrow that can renew itself, can differentiate to a variety of specialized cells, can mobilize out of the bone marrow into circulating blood, and can undergo programmed cell death, called apoptosisa process by which cells that are detrimental or unneeded self-destruct.

A major thrust of basic HSC research since the 1960s has been identifying and characterizing these stem cells. Because HSCs look and behave in culture like ordinary white blood cells, this has been a difficult challenge and this makes them difficult to identify by morphology (size and shape). Even today, scientists must rely on cell surface proteins, which serve, only roughly, as markers of white blood cells.

Identifying and characterizing properties of HSCs began with studies in mice, which laid the groundwork for human studies. The challenge is formidable as about 1 in every 10,000 to 15,000 bone marrow cells is thought to be a stem cell. In the blood stream the proportion falls to 1 in 100,000 blood cells. To this end, scientists began to develop tests for proving the self-renewal and the plasticity of HSCs.

The "gold standard" for proving that a cell derived from mouse bone marrow is indeed an HSC is still based on the same proof described above and used in mice many years ago. That is, the cells are injected into a mouse that has received a dose of irradiation sufficient to kill its own blood-producing cells. If the mouse recovers and all types of blood cells reappear (bearing a genetic marker from the donor animal), the transplanted cells are deemed to have included stem cells.

These studies have revealed that there appear to be two kinds of HSCs. If bone marrow cells from the transplanted mouse can, in turn, be transplanted to another lethally irradiated mouse and restore its hematopoietic system over some months, they are considered to be long-term stem cells that are capable of self-renewal. Other cells from bone marrow can immediately regenerate all the different types of blood cells, but under normal circumstances cannot renew themselves over the long term, and these are referred to as short-term progenitor or precursor cells. Progenitor or precursor cells are relatively immature cells that are precursors to a fully differentiated cell of the same tissue type. They are capable of proliferating, but they have a limited capacity to differentiate into more than one cell type as HSCs do. For example, a blood progenitor cell may only be able to make a red blood cell (see Figure 5.1. Hematopoietic and Stromal Stem Cell Differentiation).

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5. Hematopoietic Stem Cells - NIH Stem Cell Information Home Page

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Population Genetics in the Personal Genome Era - Carlos Bustamante
September 12, 2013 - The African Diaspora: Integrating Culture, Genomics and History.

By: GenomeTV

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Population Genetics in the Personal Genome Era - Carlos Bustamante - Video

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Gene therapy of adrenoleukodistrophy
Dra. Nathalie Cartier.

By: AsociacionAMER

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Gene therapy of adrenoleukodistrophy - Video

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New Cancer Treatment: Stem Cell Therapy
Writing 160 Project #2.

By: Emily Kaschner

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New Cancer Treatment: Stem Cell Therapy - Video

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African scientists in Nairobi to explore stem cell therapy
African Scientists are converging in Nairobi to explore ways of using regenerative medicine or stem cell therapy, to help prevent the increasing cases of non...

By: Kbc Kenya

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African scientists in Nairobi to explore stem cell therapy - Video

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