Eight European researchers develop Ion AmpliSeq Community Panel for lung and colon cancer – Video

Posted: November 7, 2012 at 2:50 pm




Eight European researchers develop Ion AmpliSeq Community Panel for lung and colon cancer
Life Technologies Ion AmpliSeq trade; Community Panels are a community-driven solution to gene panel sequencing that leverages the expertise of scientific thought leaders and the Ion Community to create gene panels for conditions ranging from cancer to inherited disease. One of the first panels was developed by eight leading European researchers who worked together with Life Technologies scientists to develop a 22-gene Ion AmpliSeq trade; Community Panel for lung and colon cancer. The panel analyzes more than 500 mutations in a single-tube assay that requires just 10 ng of DNA input per primer pool, about 25-fold less than alternative gene panel approaches. The Ion AmpliSeq trade; workflow is a simple PCR reaction that takes just 3.5 hours turn-around time. "Using classical methods to screen for mutations one at a time requires so much DNA sample, you often can #39;t look at all the mutations you want," said Dr. Pierre Laurent-Puig, MD, Ph.D., Professor at the Paris - Descartes University Medical School and a member of the OncoNetwork Consortium. "We have developed a tool that allows us to characterize tumors very easily, using only 10 ng of sample to screen more than 500 COSMIC mutations. Having these kits in our hands will accelerate throughput of the characterization of tumors and make personalized medicine a reality." The research institutions that developed the panel -- dubbed the OncoNetwork -- include Centro Ricerche Oncologiche Mercogliano, Italy; Leiter Genetik / Molekularbiologie ...From:iontorrentViews:9 0ratingsTime:05:38More inScience Technology

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Eight European researchers develop Ion AmpliSeq Community Panel for lung and colon cancer - Video

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