Nano Dangerously Big Feb. 23, 2016 Keywords such as nano-, personalized-, or targeted medicine sound like bright future. What most people do not know, is that nanomedicines can cause severe undesired effects for actually being too ... read more Unique Next Generation Sequencing-Based Panel Designed for Pediatric Cancer Research Feb. 18, 2016 A next-generation sequencing (NGS)-based panel will be designed specifically for pediatric cancer research, say scientists. The assay would be designed to target biomarkers associated with childhood ... read more Study Pinpoints Driver, Potential Target in Aggressive Pediatric Leukemia Subtype Feb. 18, 2016 Scientists report that they have discovered inactivation of the gene EZH2 as a driver and inroad to a potential therapeutic target in aggressive pediatric leukemia ... read more Feb. 15, 2016 Scientists have concluded a study of how inherited genetic variations in the NUDT15 gene cause serious chemotherapy toxicity; findings point to potential genetics-guided precision ... read more Feb. 10, 2016 A cardio-oncology program is focusing on modulating the risk factors for cardiovascular disease in men, especially those receiving androgen deprivation therapy (ADT) to treat their prostate ... read more Professors Use Cadaver DNA to Advance Genetics Literacy in Medical Curricula Feb. 9, 2016 Cadavers have long been one of the most important resources for anatomy teaching in medical school. Now, they are also at the forefront of cutting-edge genetics teaching, thanks to some innovative ... read more Proteomics and Precision Medicine Feb. 5, 2016 Researchers have used personalized proteomics to devise a successful treatment strategy for a patient with uveitis, a potentially blinding eye disease that can have many causes, making it ... read more Single-Lesion Biopsy May Be Insufficient to Choose Therapy Targeting Resistance Mutations Feb. 5, 2016 When metastatic tumors driven by drug-targetable genetic mutations become resistant to a targeted therapy drug, the usual practice is to test a single metastatic lesion for new mutations that can ... read more Researchers Patent New Methods That Allow Them to Identify the Cells Causing Metastasis in Cancer Feb. 4, 2016 Researchers have patented a new method that allows to identify the cells causing metastasis in cancer, with a simple blood ... read more Making the Leap from Sequence Data to Actionable Targets in Clinical Oncology Feb. 1, 2016 The ever-shrinking cost of DNA sequencing improves accessibility for an increasing number of people and, importantly, for the diagnosis and treatment of disease. This is particularly salient in ... read more Jan. 28, 2016 Clinical genomic sequencing is feasible in pediatric oncology and can be used to recommend therapy or pinpoint diagnosis in children with solid tumors, according to the multi-center ... read more In Lung Cancer, Not All HER2 Alterations Are Created Equal Jan. 28, 2016 Study shows two distinct causes of HER2 activation in lung cancer: mutation of the gene and amplification of the gene. In patient samples of lung adenocarcinoma, 3 percent were found to have HER2 ... read more Test Rapidly, Accurately Profiles Genetics and Treatment of Brain Tumors Jan. 27, 2016 Brain tumors can be rapidly and accurately profiled with a next-generation, gene-sequencing test recently developed. The test, called GlioSeq, is now being used by oncologists to help guide treatment ... read more Disclosure of Incidental Genetic Findings Can Have Positive Impact for Patients Jan. 26, 2016 Providing unanticipated information about risk of coronary artery disease during a genetic risk assessment for Alzheimer's disease helped some participants cope with their results, and also ... read more Inherited Genetic Markers May Predict Melanoma Survival -- And Help Plot Course of Disease Jan. 20, 2016 How long will a patient survive following the removal of a melanoma tumor? A more definitive answer to that question could come from new studies. Researchers there have discovered an inherited ... read more Important Associations Between Genetics, Sleep Behavior Identified by Study Jan. 12, 2016 A research initiative exploring the utility of genetic information in the clinical setting has published a study and identified six noteworthy genes that affect human sleep duration. The focus of the ... read more Epigenetic Regulation of Metastatic Breast Cancer Progression May Guide Prognosis, Future Therapy Jan. 7, 2016 A gene that plays a role in the development of breast cancer to metastatic disease has been identified which may help to predict disease progression and serve as a target for the development of ... read more New Approach to Diagnosing Low Back Pain, Revealed by Clinical Study Jan. 7, 2016 A new, personalized approach to diagnosing low back pain has been discovered by researchers. Low back pain is the second most common cause of physician visits in the US and contributes to an ... read more Lung Cancer Clinical Trial Finds Lung Function Without Additional Imaging Jan. 6, 2016 A clinical trial is evaluating a new method for pinpointing and sparing healthy lung tissue during lung cancer radiotherapy. The group is applying advanced image analysis techniques to 4D CT scans ... read more Jan. 6, 2016 Researchers have found the 'bad seeds' of liver cancer and believe they could one day reprogram them to remain responsive to cancer treatment, a new study has found. The key to disrupting ... read more

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