Video Link: https://www.youtube.com/watch?v=yVb4RhQh4Sw

Regenerative medicine from an engineering perspective
The Miyata Group at Keio University is doing research that helps with regenerative medicine, by looking at cells and tissues from the viewpoint of engineering. Q. Growing cells, bone, and cartilage outside the body is usually done just by culturing them, using in jelly- or sponge-like materials. In that case, the cells themselves form 3D tissue from nutrients in the culture medium, resulting in block-like solids. However, the strength and hardness of the tissue are by no means sufficient. Currently, the strength obtained is ten to a hundred times less than that of similar materials in the human body. Our approach is to try giving the materials some kind of stimulus -- in particular, a physical or mechanical stimulus. When making cartilage from cells grown outside the body, we wondered if we could produce harder, stronger cartilage by compressing the cell-containing hydrogel rhythmically, at the same frequency as in walking. The Miyata Group designed, built, and tested their own machine for giving cells a compressive stimulus at the same frequency as walking. Compared with cartilage cells grown in hydrogel without the stimulus, the resulting cartilage was twice as hard. In another project, the researchers are working on cell sorting technology, to separate cells with a therapeutic effect from among all the cultured cells. Q. Currently, there are commercially available technologies that use fluorescent pigments, magnetic particles, and magnetic beads. But equipment like ...From:keiouniversityViews:0 2ratingsTime:04:25More inScience Technology

See the original post here:
Regenerative medicine from an engineering perspective - Video

Comments are closed.