It is astonishing how the cosmetic industry uses medical discoveries and put these formulas into skin cream jars.

In 2009 the American company Voss laboratories was the first that introduced stem cell active ingredients into a cosmetic product. Due to the fact that the company didnt reveal their secret ingredients, it created a worldwide rumor that the company might be using human stem cells.

The world started to question if this would be ethical and safe.

Coming from the medical stand point: with human stem cells you can actually build and rebuild human organs but also carcinogenic cell. For that reason it created great concerns.

Now days many trendsetting companies producing stem cell creams and serums that dont use human stem cells

Stem cells are a class of undifferentiated cells that are able to differentiate into specialized cell types

Adult or somatic stem cells exist throughout the body after embryonic development and are found inside of different types of tissue. These stem cells have been found in tissues such as the brain, bone marrow, blood, blood vessels, skeletal muscles, liver, and the Skin ( basal layer and fat layer) . They remain in a quiescent or non-dividing state for years until activated by disease or tissue injury.

Adult stem cells can divide ( copy) or self-renew indefinitely, enabling them to generate a range of cell types from the originating organ or even regenerates the entire original organ.

Plant Stem Cells benefits human skin.

Stem cells from a rare red grape variety provide the basis for Israel based company On-Macabim latest skin care ingredient.

This variety is one of the few red grapes that have red flesh and juice the majority have red skin but white flesh and juice which is due to the high quantity of anthocyanins in the fruit.

The anthocyanins, also present in the flesh, leading to higher antioxidant levels overall.

The technology was developed last year and allows to extract stem cells from the plant which can then be formulated into a cosmetic ingredient to help protect the stem cells in human skin.

To harvest the stem cells the company first induces a wound in the plant which causes the surrounding cells to dedifferentiate (turn back into stem cells) and form a wound healing tissue called a callus.

Once the wound has healed these cells can differentiate again and build new tissue

According to On-macabim, these plant stem cells contain components and epigenetic factors that can protect human skin stem cells form UV radiation, inflammation, oxidative stress, neutralize free radicals and reverse the effects of photoaging.

Stem cells are found in the epidermal layer of the skin and are involved in skin growth and regeneration. If they are harmed by UV radiation,

their power to regenerate will be jeopardized.

Grape stem cells have the ability to promote healthy skin proliferation.

Grape Stem Cells Counteract Negative

Effects of UV Radiation on

Skin Stem Cells

In an in-vitro study, skin stem cells were treated with and without

the Grape Stem Cells.

Some were exposed to UVA+UVB-light; others were unexposed.

CFE was determined in each case.

Results confirmed that cells treated with the Grape Stem Cells increased

the CFE of the skin stem cells. A 58% decrease in CFE was observed

when skin stem cells were exposed to UV radiation (control).

However, the presence of the Grape Stem Cells counteracted the negative effect of UV radiation on the cells as the CFE remained at the same level when exposed to the UV radiation.

Therefore, the Grape Stem Cells protect skin stem cells against UV stress.

Benefits of the Grape Stem Cell products

Regenerative, repair and rejuvenating properties

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Stem cell and skin care. | Esthetics Association Florida

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